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    Eddie Cabrera, skype user eddie.cabrera6 | 3

    READ THE FOLLOWING TEXT AND ANSWER THE QUESTIONS BELLOW

    How to eliminate 50 percent of all coronary events

    By Dr. Barry Sears, founders of zone diet

    The European Society of Cardiology estimates a 50 percent reduction of coronaryevents if you can stabilize soft, vulnerable plaques (1). We are often led to believethat plaques you can see on an angiogram are killer plaques. Its true that if they

    are large enough to obstruct blood flow, they will decrease oxygen transfer to theheart muscle cells making them more tired with less effort.

    This is the definition of stable angina. It simply means it takes less effort to over-exert the heart muscles before they fatigue. However, you need approximately a 90

    percent total obstruction of the blood vessel to develop stable angina. Theseplaques account for most of the plaques you might find in an angiogram. This iswhy if you take an angiogram, you are often immediately wheeled into theoperating room to have a stent put into the artery with the belief you are only

    seconds away from an immediate heart attack and death.However, the same angiogram cant see a few plaques (because they are so small),known as the soft, vulnerable ones. When soft, vulnerable plaques rupture (like a

    pimple), then you have the death and disability (i.e., damaged heart tissue) that

    truly characterize heart disease. Technically, this is called an acute coronary event,and it has very little to do with the stable plaques that can cause angina. It is this

    small number of rogue soft, vulnerable plaques that are the true killers in heartdisease (2,3).

    The ultimate cause of plaque rupture is cellular inflammation inside the plaque.

    Cellular inflammation degrades the fibrous external coating of the plaque. Usuallyinside these soft, vulnerable plaques are also a lot of macrophages engorged withlipids. This is called the necrotic core. When the plaque bursts, these lipid pools

    are released into the bloodstream causing platelet aggregation and the rapid

    blockage of the artery resulting in a complete restriction of blood flow (as opposed

    to a limited restriction of blood flow with a typical stable plaque that will neverrupture). It is estimated that about 75 percent of all coronary events are caused byruptures of the soft, vulnerable plaques (2).

    As I mentioned above, the really scary part of this story is that there is no type ofimaging technology that can detect dangerous soft, vulnerable plaques. In essence,you dont know if you have them or not. This is why the prediction of impeding

    cardiovascular events remains a guessing game. Even more interesting is that

    these soft, vulnerable plaques seem to form rather quickly (in about 10 years) asopposed to growing slowly over a lifetime (4). Moreover, the rate of growth of

    these soft, vulnerable plaques is strongly correlated with increasing insulin levelsin the blood (4).

    So what does this mean for people who dont want to die from a sudden rupture of

    soft, vulnerable plaques that cant be detected? The first thing is to reduce theinflammation within the plaque. Surprisingly, there is only one clinical study that

    has ever been published that addressed this question, and it used fish oil (5). Thisstudy indicated that if you give patients relatively high doses of fish oil, you could

    http://www.zonediet.com/blog/2011/01/31/another-good-reason-to-eat-your-fruits-and-vegetables/http://www.zonediet.com/blog/2011/01/31/another-good-reason-to-eat-your-fruits-and-vegetables/
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    see a definite remodeling of the soft, vulnerable plaques in about 40 days

    compared to subjects taking a placebo composed of safflower oil. The plaques inthe subjects taking the fish oil became less inflamed, had higher levels of omega-3fatty acids, fewer macrophages and more well-formed fibrous caps compared to

    those taking the placebo. So taking a therapeutic level of fish oil for a lifetime

    seems to be a good way to reduce the rupture of these plaques.Another way to potentially reduce their formation in the first place is lower insulin

    levels. The reason insulin levels are elevated is because organs, such as the adiposetissue, the liver and the muscles, are also inflamed (6). The best way to reduce that

    systemic inflammation is to follow the anti-inflammatory diet and take therapeutic

    levels of fish oil for a lifetime. Your success is best measured by the AA/EPA ratioin the blood. Call me crazy, but I think thats what I have been recommending for

    the past 16 years (7).

    References

    Yia-Herttulala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Merrmann J,

    Hoefer IM, Juekma JW, Krams R, Kwak BR, Marx N, Maruszeqica M, Newby A,

    Pasterkamp G, Serruys PWJC, Waltenberger J, Weber C, and Tokgozoglu L.Stabilization of atherosclerotic plaques. Thomobosis and Haemostasis 106: 1-19

    (2011)Schaar JA, Muller JE, Falk E, Virmani R, Fuster V, Serruys PW, Colombo A,

    Stefanadis C, Ward Casscells S, Moreno PR, Maseri A, and van der Steen AF.

    Terminology for high-risk and vulnerable coronary artery plaques. Report of ameeting on the vulnerable plaque. Eur Heart J 25: 1077-1082 (2004)

    Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, Ford E,

    Furie K, Go A, Greenlund K, Haase N, Hailpern S, Ho M, Howard V, Kissela B, Kittner

    S, Lackland D, Lisabeth L, Marelli A, McDermott M, Meigs J, Mozaffarian D, Nichol G,ODonnell C, Roger V, Rosamond W, Sacco R, Sorlie P, Stafford R, Steinberger J,Thom T, Wasserthiel-Smoller S, Wong N, Wylie-Rosett J, and Hong Y. Heart disease

    and stroke statistics2009 update: a report from the American Heart Association

    Statistics Committee and Stroke Statistics Subcommittee. Circulation 119:480-486(2009)Hagg S, Salehpour M, Noori P, Lundstrom J, Possnert G, Takolander R, Konrad P,

    Rosfors S, Ruusalepp A, Skogsberg J, Tegner J, and Bjorkegren J. Carotid plaque

    age is a feature of plaque stability inversely related to levels of plasma insulin.

    PLoS One 6: e1824 (2011)Thies F, Garry JM, Yaqoob P, Rerkasem K, Williams J, Shearman CP, Gallagher PJ,

    Calder PC, and Grimble RF. Association of n-3 polyunsaturated fatty acids withstability of atherosclerotic plaques: a randomized controlled trial. Lancet 2003361: 477-485 (2003)Sears, B. Toxic Fat. Thomas Nelson. Nashville, TN (2008)

    Sears B. The Zone. Regan Books. New York, NY (1995)

    Nothing contained in this blog is intended to be instructional for medial diagnosisor treatment. If you have a medical concern or issue, please consult your personal

    physician immediately.

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    Eddie Cabrera, skype user eddie.cabrera6 | 5

    Questionsa) What is the definition of angina?b) How you can control de coronary events?c) How inflammatory processes affecting the liver and other tissues acids in coronary

    events?

    d) How could we develop a diet-inflammatory?

    Prepare a Little presentation about the following text of Dr. Sears

    Changing gene expression

    I have often stated that the real power of the Zone Diet is to change geneexpression, especially the expression of anti-inflammatory genes. What I never

    realized is how rapid gene expression could occur. Now, new research from

    Norway gives me the answer (1). It takes about 24 hours!This pilot study is on the effect of diet on gene expression in healthy obeseindividuals. Interestingly, when the researchers calculated the estimated daily

    calorie requirements for these subjects necessary to maintain their weight, theywere surprised that they were already eating 250 fewer calories per day thanpredicted to maintain their current weight. So much for the fact that obese

    individuals are fat because they eat more calories than they need to maintain their

    weight. In fact, this observation was confirmed in an earlier study in which thenumber of calories consumed by obese and lean individuals did not vary, but the

    obese individuals consumed fewer meals consisting of larger servings (2).So what the Norwegian researchers did was simply maintain the same number of

    calories the subjects were already eating and change the macronutrient balance tobe very close to the Zone Diet (30 percent carbohydrates, 30 percent protein, and40 percent fat). Then the subjects consumed six meals containing about 460

    calories evenly spaced throughout the day so that the total calories consumed at

    any one time was moderate. Just making those two simple dietary changes resultedin more than an eight-poundweight lossin 28 days. The levels of body fat didnt

    change since the number of calories consumed was exactly the same as they werepreviously consuming. However, it appears that evenly spacing the meals andreducing the calorie size of the meals resulted in less insulin production and

    therefore less retained water.Then they looked to see if they could find any changes in gene expression in both

    the fat cells and the blood with the dietary changes. Amazingly they founddramatic changes in only 24 hours. Of the 16,000 genes they could identify, about

    60 percent remained unchanged in their expression, but 40 percent were eitherturned on (i.e., up-regulated) or turned down (i.e., down-regulated). Interestingly,

    the changes seen in the first 24 hours were held constant throughout the 28 daysof the experiment.

    Upon further analysis, the up-regulated genes corresponded to those that had anti-

    inflammatory properties, and the down-regulated genes were those associatedwith chronic disease conditions, such asdiabetesandheart disease. Furthermore,

    since these changes in gene expression occurred within 24 hours of the dietary

    change, they could not be attributed to any change in body weight and fat loss.

    http://www.zonediet.com/blog/2011/01/01/weight-loss-or-fat-loss-it-makes-a-difference/http://www.zonediet.com/blog/2011/01/01/weight-loss-or-fat-loss-it-makes-a-difference/http://www.zonediet.com/blog/2011/01/01/weight-loss-or-fat-loss-it-makes-a-difference/http://www.zonediet.com/blog/2010/10/05/for-losing-weight-exercise-is-good-diet-is-better/http://www.zonediet.com/blog/2010/10/05/for-losing-weight-exercise-is-good-diet-is-better/http://www.zonediet.com/blog/2010/10/05/for-losing-weight-exercise-is-good-diet-is-better/http://www.zonediet.com/blog/2011/01/31/another-good-reason-to-eat-your-fruits-and-vegetables/http://www.zonediet.com/blog/2011/01/31/another-good-reason-to-eat-your-fruits-and-vegetables/http://www.zonediet.com/blog/2011/01/31/another-good-reason-to-eat-your-fruits-and-vegetables/http://www.zonediet.com/blog/2011/01/31/another-good-reason-to-eat-your-fruits-and-vegetables/http://www.zonediet.com/blog/2010/10/05/for-losing-weight-exercise-is-good-diet-is-better/http://www.zonediet.com/blog/2011/01/01/weight-loss-or-fat-loss-it-makes-a-difference/
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    Fortunately, I had the opportunity to have dinner with the lead author of the study

    to discuss her work while I was in Europe last week. She told me that she hasexpanded the number of subjects in several new trials, and the results remain thesame. I also found out that she has been following my work for many years.

    This type of study only confirms the power of genetic analysis to demonstrate how

    a highly structured diet with the correct macronutrient content can rapidly altergenetic expression and hence controls your future health. But the door swings both

    ways. An unbalanced diet will have just the opposite genetic effects. While I havealways been impressed by the power of the Zone Diet, this new experimental data

    takes my respect for the Zone Diet to a new level of awe, even by me.

    ReferencesBrattbakk H-R, Arbo I, Aagaard S, Lindseth I, de Soysa AK, Langaas M, Kulseng B,

    Lindberg, and Johansen B. Balanced caloric macronutrient composition down

    regulates immunological gene expression in human blood cells-adipose tissue

    diverges. OMICS 15: doi:1089/omi.2010.0124 (2011)

    Berg C, Lappas G, Wolk A, Strandhagen E, Toren K, Rosengren A, Rosengren A,Thelle D, and Lissner L. Eating patterns and portion size associated withobesityina Swedish population. Appetite 52: 21-26 (2009)

    http://www.zonediet.com/blog/2010/06/21/united-states-major-export-obesity/http://www.zonediet.com/blog/2010/06/21/united-states-major-export-obesity/http://www.zonediet.com/blog/2010/06/21/united-states-major-export-obesity/http://www.zonediet.com/blog/2010/06/21/united-states-major-export-obesity/
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    STUDY GUIDE N 5

    Muscles sequence and Booster sequence

    I.- Elija la alternativa correcta

    1. - Todas las sequencias fitnes comienzan la morning routine con el producto

    a) Sharp shower gel

    b) Tea tree SOS spray and elemis skin brush

    c) Nourishing milk bath

    d) ninguna de las anteriores

    2. - La funcin de Elemis skin brush es:

    a) Remove dead skin cells

    b) Kick start the circulation

    c) prepare the skin for absobs the oils

    d) all previous

    3. - La funcin de rosemary en Musclease active body oil es

    a) Descontracturar, relajar

    b) Embellecer, fortalecer

    c) Calmar, humectard) ninguna de las anteriores

    4.- Instant refreshing gel puede ser usado

    a) Para relajar los msculos en especial, los hombros, las sienes y despus de un viaje

    cuando los msculos estn cansados

    b) Para refrescar la piel

    c) para los pies cansados

    d) ninguna de las anteriores

    5.- Se utiliza burning lime essential oil en la maana porque

    a) los ctiricos estimulan y es perfecta para empezar el dia

    b) porque el limn no irrita

    c) porque tiene un aroma agradable

    d) ninguna de las anteriores

    6.- Burning lavander essential oil es buena para la noche porque

    a) relaja los hombros

    b) embellece y mejora el sueo

    c) ayuda en las afeitadasd) ninguna de las anteriores

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    II.- Preguntas de desarrollo

    1.- Mencione tres ingredientes de Muscleases herbal bath

    2.- Mencione dos beneficos de muscle super soak

    III. Cross words

    Across

    3. What is the principal power of tea tree sos spray?

    5. Vitallity capsules boost the level of

    6. ingrediente principal en deep drenaige capsules

    7. Sharp shower gel contain...

    Down

    1. the bristles of the elemis skin brush are made from...

    2. algae from Cal-metab plus

    4. Silhouette capsules help control ...

    1 2

    3 4

    5

    6

    7

    EclipseCrossword.com

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    Eddie Cabrera, skype user eddie.cabrera6 | 9

    Answers

    Across

    3. ANTISEPTICWhat is the principal power of tea tree sos spray?

    5. STAMINAVitallity capsules boost the level of

    6. PARSLEYingrediente principal en deep drenaige capsules

    7. PEPPERMINTSharp shower gel contain...

    Down

    1. CACTUSthe bristles of the elemis skin brush are made from...

    2. ASCOPHYLLUMalgae from Cal-metab plus

    4. CELLULITESilhouette capsules help control ...

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    Eddie Cabrera, skype user eddie.cabrera6 | 10

    STUDY GUIDE N 6

    Stress sequence

    I.- Elija la alternativa correcta

    1.- Exotic island flower body balm contiene

    a) Calendula and rosemary

    b) Calendula and spirulina

    c) Calendula and St Johns wort

    d) ninguna de las anteriores

    2.- Tea tree SOS spray tiene propiedades antispticas porque

    a) Limpia la piel y la deja suaveb) elimina virus y bacterias

    c) puede ser usado con agua

    d) ninguna de las anteriores

    3.- En instant refreshing gel el rnica tiene la funcin de

    a) relajar

    b) descontracturar y eliminar los traumas musculares

    c) humectar

    d) ninguna de las anteriores

    4.- Los productos que corresponden a la evening routine of stress sequence son

    a) Tea tree SOS body spray, instante refreshing gel and devils apron cream

    b) Tea tree Sos body spray, elemis skin brush, wild lavender shower gel, De stress

    massage oil, burning lavender oil

    c) Los mismos productos de morning routine

    d) ninguno de los anteriores

    5.- En weekly routine Devils mint body scrub contiene

    a) Apron and see weedb) Devils apron seaweed and peppermint

    c) strawberry and apple

    d) ninguna de las anteriores

    6.- Milk bath es bueno para las personas que padecen de

    a) insolation

    b) psoriasis and ecsema

    c) cncer

    d) ninguna de las anteriores

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    Cross words

    Across

    3. the burning oil of the evening routine

    5. instant refreshing gel is perfect for pregnant ladies on those swollen...

    6. aching muscle super soak is special for .... man and women

    Down

    1. The first ingredients of exotic island flower body balm

    2. De- stress massage il contain lavender and...

    4. in aching muscle super the key ingredients are Rosemary and...

    1

    2

    3

    4

    5

    6

    EclipseCrossword.com

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    Answers

    Across

    3. LAVANDERthe burning oil of the evening routine

    5. ANKLESinstant refreshing gel is perfect for pregnant ladies on those swollen...

    6. SPORTSaching muscle super soak is special for .... man and women

    Down

    1. CALENDULAThe firts ingredients of exotic island flower body balm

    2. CHAMOMILEDe- stress massgae il contain lavender and...

    4. JUNIPERin aching muscle super the key ingredients are Rosemary and...

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    STUDY GUIDE N 7

    DETOXIFICATION SEQUENCEI.- Choose the correct alternative

    1.- Cellutox active body concentrate is

    a) an energising citrus body oil

    b) an aromatherapeutic product of skin care

    c) an essencial oil

    d) ninguna de las anteriores

    2.- Cellutox active body concentrate contain

    a) lemon and arnica

    b) lemon and lime

    c) lemon and juniper

    d) ninguna de la anteriores

    3.- Vitamin-rich body lotion is a

    a) nourishing serum

    b) potent sources of nourishing minerals

    c) is a care lotion for illness skin

    d) ninguna de las anteriores

    4.- Cellutox herbal bath combats again

    a) fatigue and mental dullnes

    b) cellulite and toxins

    c) help to reduce the excess of fat

    d) ninguna de las anteriores

    5.- Exotic lime and ginger salt glow contain

    a) lime and rosepetal essential oil

    b) lime and pomegrades

    c) lime and ginseng

    d) ninguna de las anteriores

    6.- Japanese camellia oil is present in

    a) Cellutox line

    b) Cal metab plus capsules

    c) Milk bath

    d) ninguna de las anteriores

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    Eddie Cabrera, skype user eddie.cabrera6 | Cross words 14

    CROSS WORDSAcross

    1. the milk bath can be used incluses for...5. essential oil enhance the sleep of the guest

    6. second ingredient of witamin-rich body lotion

    Down

    2. capsules for the second month of the booster sequence

    3. second ingredient of sharp shower gel4. principal ingredients of the salt glow

    1 2

    3 4

    5

    6

    Ecli seCrossword.com

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    Eddie Cabrera, skype user eddie.cabrera6 | Enviromental safety and waste

    magement

    16

    a) What equipment requires a substance labeled with the letter E?

    b) Name three products considered as the basis

    c) How should be stored acids?

    d) Why many acids and oxidizers are rated red?

    III. link the right list of equipment with the right letter

    A Air line hood or mask, gloves, special body protection, bootsB Safety glasses, gloves, dust respirator

    C Safety glasses, gloves dust and vapor respiratorD Splash goggles, gloves, apron, vapor respirator

    E Safety glasses and glovesF Face shield, gloves, apron

    G Safety glasses

    H Safety glasses, gloves and apron

    I Safety glasses and glovesJ Ask supervisor or fleet safety programs for handling instructions

    K Safety glasses, gloves, vapor respiratorX Splash goggles, gloves, apron, dust and vapor respirator

    IV.- Complete de following grid with the missing information

    Flamable liquids

    Must be stored on lowers two shelves with

    a containment tray placed under bottomshelf i.e. Cool blue

    Oxidizers

    Must be stored on lowers two shelves witha containment tray placed under bottom

    shelf i.e. Cleaning soaps, oils, etc.

    General storage

    Must be stored in a separate room from any

    food packaging

    V.- Complete the following statements

    a) For storage and usage of each product, read the ______________ carefully on the product

    bottle or box

    b) For disposal of each product, refer to the specific _____________ for that product and

    contact the _______________ on board

    c) Many products used in our spas can be ____________ and combustible

    d) ________________ must be stored in a flammable storage cabinet. They are identified, in red

    on the product listing on the nest frame. They must be cared for property.

    e) Product classified in _____, ______, _______ or ________ require less care, but ensure

    instructions are followed.

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    magement

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    f) Items in _______ are toxic and have to be stored in a separate room

    VI. Cross word

    Following the example of waste program of Carnival Cruises line, complete the crossword

    Across

    2. Glass only

    4. plastic and paper

    Down

    1. Cans only

    3. broken chinaware

    5. Food only....

    1

    2 3

    4 5

    Ecli seCrossword.com

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    Eddie Cabrera, skype user eddie.cabrera6 | Enviromental safety and waste

    magement

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    VII.- Complete the following grid with the missing information

    These are 4 classifications defined by US regulations for manage the waste

    Universal waste

    This is any discarded material that is nor

    hazardous or regulates i.e. food waste,regular solid waste.

    Hazardous Waste

    This is defined as certain types of waste,

    that due to their chemical and biological

    composition, must be controlled for proper

    storage and disposal

    Appendix 1

    Attached information from the training DVD and respect the symbols of chemical hazardclassification

    & SAFETY

    Health & SafetyChemical Spills

    Spills of this nature can potentially release harmful toxic vapours

    In the event of a chemical spill:

    Dont attempt to clean it up, instead report it to your supervisor

    and warn others to keep away until help arrives

    Hazards are classed by severity on a rating scale from

    0-4; 0 representing a minimum hazard and 4 indicating

    a severe hazard.

    Each hazard class also uses a different primary colour to

    represent a different type of hazard. Blue means health,

    red means flammability and yellow means reactivity.

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    Appendix 2

    NFPAHAZARD RATING SYSTEM

    Northeastern University's laboratory doors are posted with emergencyinformation to warn occupants and The Boston Fire Department personel of thepresence and identification of hazardous materials inside each laboratory. The

    National Fire Protection Association (NFPA) has developed a system for indicating

    the health, flammability, reactivity and special hazards for many common

    chemicals through use of the NFPA 704 Diamond. The hazard rating for thelaboratory is determined by looking at all the chemicals, gases and special lab usesin the laboratory and coming up with a rating for each hazard category based on

    criteria established below.

    Please read the rating information in each catergory, take an inventory of yourlaboratory and rate each category accordingly. To look up a rating for a particular

    chemical click on the link at the bottom of the page. If you do not find the chemicallisted, a review of the chemicals MSDS sheet may help you rate the chemical in

    question. To look up a chemicals MSDS click on the "MSDS" link at the bottom of

    the page.If there are any questions regarding a chemical rating, please either email yourquestion or call the Office of Environmental Health and Safety at x2769.

    If you have a new laboratory or are a new Principal Investigator, please click one ofthe following links:

    New Laboratory or Add LaboratoryNew Principal Investigator

    Rating SummaryHealth

    Use the most severe rating code regardless of volume.Health (Blue)Detailed Description of Health Rating

    4 DangerMay be fatal on short exposure. Specialized protective equipmentrequired

    3 Warning Corrosive or toxic. Avoid skin contact or inhalation

    2 Warning May be harmful if inhaled or absorbed1 Caution May be irritating

    0 No unusual hazard

    FlammabilityThe greatest volume of one code determines the marking. The only exception is if a

    more severe code has a volume of 3 gallons or greater, then that code is used

    instead of a lower code of greater volume. If the laboratory total volume offlammables or combustibles is less than one pint for all, then the rating for the

    laboratory for this area shall be zeroFlammability (Red)Detailed Description of Flammable Rating

    4 Danger Flammable gas or extremely flammable liquid

    http://www.ehs.neu.edu/departments/updatedata.htmlhttp://www.ehs.neu.edu/departments/updatedata.htmlhttp://www.ehs.neu.edu/departments/updatedata.htmlhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/health/documents/health.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/health/documents/health.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/health/documents/health.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/flammability/documents/flammabi.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/flammability/documents/flammabi.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/flammability/documents/flammabi.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/flammability/documents/flammabi.htmhttp://www.ehs.neu.edu/laboratory_safety/general_information/nfpa_hazard_rating/health/documents/health.htmhttp://www.ehs.neu.edu/departments/updatedata.htmlhttp://www.ehs.neu.edu/departments/updatedata.html
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    3 Warning Flammable liquid flash point below 100F

    2 Caution Combustible liquid flash point of 100 to 200F

    1 Combustible if heated

    0 Not combustible

    ReactivityUse the most severe rating code regardless of volume.

    Reactivity (Yellow)Detailed Description of Reactivity Rating

    4 Danger Explosive material at room temperature

    3 DangerMay be explosive if shocked, heated under confinement or mixed with

    water

    2 Warning Unstable or may react violently if mixed with water

    1 Caution May react if heated or mixed with water but not violently

    0 Stable Not reactive when mixed with water

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