Engineering and Physical Sciences Research Council

Manufacturing the FutureENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL

Dr Mark Claydon-SmithTheme Lead

EPSRC Delivery Plan: 2011 - 2015

Investigator-DrivenResearch

Energy

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Digital Economy

ETI

£439M

£1645M

£322M

£304M

£72M£107M

£48M£68M

Research Grants

Fellowships &Studentships

Knowledge Transfer

Projected Spend by Theme

Values shown are cumulative over four years

HEALTHCARE TECHNOLOGIESRe-Distributed Manufacturing

Healthcare Technologies Vision

• Build critical mass around UK research strengths in engineering and physical sciences that underpin healthcare

• Maximising business, charity and clinical engagement in research - increasing translation to products / practices

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MRC (including UK Regenerative Medicine Platform, Biomedical Catalyst, AMR)

EPSRC, BBSRC

Innovate UK, including Health KTN, Biomedical Catalyst, Cell Therapy & Precision Medicine

Catapult, Innovation Platforms (Stratified Medicine, Assisted Living )

National Centre for the Replacement Refinement and Reduction of Animals In Research (NC3Rs)

Wellcome Trust, Cancer Research UK

DoH, including NIHR HTCs, NHS England and AHSNs

Developing the Healthcare Technologies strategy

New Healthcare Technologies Strategy

Grand Challenges

Healthcare focussed challenges to which EPS researchers can make a significant contribution:

Developing Future TherapiesSupporting the development of novel therapies with technologies to enhance efficacy, minimise costs and reduce risk to patients.

Frontiers of Physical InterventionRestoring function, and optimising surgery and other physical interventions to achieve high precision with minimal invasiveness.

Optimising TreatmentOptimising care through effective diagnosis, patient-specific prediction and evidence-based intervention.

Transforming Community Health and CareUsing real-time information to support self-management of health and wellbeing, and to facilitate timely interventions.

Cross-cutting research capabilities

Areas of research which are essential for delivering the grand challenges:

Advanced materialsDevelopment, characterisation & processing of advanced materials with novel chemical, physical or mechanical properties, for health-related applications.

Disruptive technologies for sensing and analysisInnovative sensing systems or analytical technologies that could have a transformative impact on prediction, diagnosis and monitoring in healthcare.

Future manufacturing technologiesTechnologies that will enable health-related manufacturing processes, products and systems to function with high precision, efficiency, reliability and repeatability.

Cross-cutting research capabilities (2)

Medical device design and innovation Design, development, evaluation and production of cost-effective, reliable and effective medical devices.

Novel computational and mathematical sciencesDevelopment of innovative computational and mathematical methods for prediction, analysis and modelling in healthcare.

Novel imaging technologiesDevelopment of next generation imaging technologies for diagnostic, monitoring and therapeutic applications; with improved accuracy, affordability and incorporating new modalities.

Impact and translation toolkit

To encourage researchers to embed thinking about translation and impact into the planning and development of research.

Highlights a number of topics for researchers to consider:

Ethics Health economics and evaluation Public engagement Regulation Research project design Responsible innovation User engagement

Could form part of the pathways to impact for proposals, and associated resources may be requested.

Will be key part of future HT calls for proposals.

Priorities for HT for 15/16

Finalising and launching grand challenges

Investing in early career researchers to build multidisciplinary teams

Encouraging environments that support multidisciplinary working in healthcare technologies and supporting multidisciplinary teams

Continuing to work with other funders e.g. Antimicrobial Resistance (led by MRC) Regenerative Medicine Platform (MRC, BBSRC, ARUK) Molecular Pathology (MRC) CRUK and Wellcome Trust

Continuing to grow critical mass Programme Grants Longer term support

Further support for translating research along the pathway

Current Funding Opportunities

Healthcare Technologies Challenge Awards (£10M)

Closing date: 14th May 2015

Support available for 10 personal awards

Aimed at future leaders – within 8 years of first

permanent post

Applications invited in the 4 grand challenges

Contacts: Vicky Marlow, Mark Tarplee

Translational Alliance Platforms (£4M)

Closing date: 28th May 2015

Support for developing new partnerships to deliver

impact from EPSRC research grants

Engineering and Healthcare Technologies only

Remit covers: Synthetic Biology, Chemical and

Formulation Engineering, Robotics and Autonomous

Systems, and Microsystems

Contacts: Anna Angus-Smyth, Martin Champion

Current Funding Opportunities (2)

Cancer Research UK Multidisciplinary Project Awards Encouraging collaborations between biomedical researchers and the

EPS community

Creative research ideas across the breadth of areas relevant to cancer

including detection technologies, drug delivery technologies, imaging

CRUK to commit £5M per annum for next 5 years

EPSRC to co-fund 2nd and future calls

1-page outline to CRUK by 25th March 2015 for next round

Full proposal deadline (if accepted) 25th May 2015

Contact: David Clarke (CRUK)

Developing non-animal technologies CR&D competition Led by Innovate UK with partners: BBSRC, EPSRC, MRC and NC3Rs

Will support projects that will improve the discovery of new human and

veterinary medicines, agrochemicals and chemicals. In particular, their

assurance for effectiveness and safety as they are developed.

Contact: Katie Daniel

Future Funding Opportunities

Healthcare Technologies Grand Challenges NetworkPlus

(~£2M)

Call published June 2015

Aim to build interdisciplinary communities aligned to our

grand challenges and cross-cutting research capabilities.

Support available for preliminary or feasibility style

research to kick start new collaborations within the

network.

Contacts: Sarah Hobbs, Katie Daniel

MANUFACTURING THE FUTURERe-Distributed Manufacturing

Compelling research opportunity

Pathway to manufacturing:

Products

Production at scale

Industrial system

Science for Production

Cross-cutting strategies

EPSRC Centres for Innovative Manufacturing

Strategic focus in areas of national importance

Manufacturing Leadership

Next generation of manufacturing innovators and research leaders

Access to Global Economies

Align international collaboration with manufacturing value chains

Working across the UK Innovation Landscape

Partnerships with business, Innovate UK and Government

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Research challenges

Priorities for Investment 2011-2016

Innovative Production Processes

Transformative processes and technologies for advanced manufacturing industries.

Sustainable Industrial Systems

Technologies and operations to reduce usage of material, water and energy resources in manufacturing processes.

Manufacturing Informatics

Novel ICT and computer science applied to manufacturing processes and systems.

Frontier Manufacturing

Creating new manufacturing opportunities from emergent scientific developments.

Emerging Manufacturing Technologies

DRAFT

CURRENT RESEARCH PORTFOLIORe-Distributed Manufacturing

Svetan Ratchev, Nottingham UniversityCloud Manufacturing - Towards Resilient and Sustainable High Value Manufacturing(EP/K014161/1 £2.4M)

Enabling, Transformative ICTDelocalised, distributed, “cloud” manufacturing

Bit by Bit: Capturing the value from the digital fabrication ‘revolution’

Aims• How will digital fabrication affect the

manufacturing landscape?

• What impacts will digital fabrication have on manufacturing in the UK?

• How can UK firms become leaders in the age of digital manufacturing?

Approach > Mapping• What are the barriers /enablers in the

emergence and diffusion of digital fabrication?

• What traditional/disruptive business models have digital fabrication technologies enabled?

• What future scenarios may result from the diffusion of digital fabrication technologies?

www.gartner.com

Phaal, R., E. O'Sullivan, M. Routley, S. Ford and D. Probert (2011). "A framework for mapping industrial emergence." Technological Forecasting and Social Change 78(2): 217-230.

www.dfab.info

EPSRC Centre for Innovative Manufacturing in Medical DevicesProf John Fisher, University of Leeds

Personalised healthcare, Localised production

Near patient cell processing Dave Williams, Mark McCall (Loughborough), May Win Naing (now Singapore)

Develop from current clinical practice

Demonstrate modular technology/automation of near patient cell (blood) processing

Process design/redesign needed to accommodate variability (e.g. for patient-patient, donor-patient input)

Further research to address regulatory “show-stopper” and build scientific consensus

ADVANCED MATERIALS

Developing applications, production technologies and future processes that incorporate advanced functional materials.

Manufacturing Advanced

Functional Materials

Material

Sciences

Material Manufacturing

Material Engineering

Successful MAFuMa Programmes (Announced 19 Dec 2014)

Research Programme Title/Grant Principal Investigator Lead Organisation Co-Investigator OrganisationsTotal Grant Value

Novel manufacturing methods for functional electronic textiles

Stephen Beeby University of Southampton Southampton Nottingham Trent £2.8m

Wearable and flexible technologies enabled by advanced thin-film manufacture and metrology

Harish Bhaskaran University of OxfordUniversity of ExeterUniversity of Southampton University of Oxford

£3.1m

Advanced Nanotube Application and Manufacturing Initiative (ANAM initiative)

Norman Fleck University of CambridgeUniversity of Cambridge University of Ulster

£3.6m

Advanced Flow Technology for Healthcare Materials Manufacturing

Asterios Gavriilidis UCL UCL Brunel £3.2m

Manufacturing and Application of Next Generation Chalcogenides

Daniel Hewak University of SouthamptonSouthampton Exeter Cambridge Heriot-Watt Oxford

£3.1m

Self-assembling Perovskite Absorbers - Cells Engineered into Modules (SPACE-Modules)

Peter Holliman Bangor University Swansea Oxford £3.2m

Ultrafast Laser Plasma Implantation- Seamless Integration of Functional Materials for Advanced Photonics (SeaMatics)

Gin Jose University of Leeds Leeds Cambridge York Sheffield £3.1m

Manufacturing of nano-engineered III-nitride semiconductors

Philip Shields University of Bath Bath Sheffield Bristol Strathclyde £3.0m

Strategic Equipment Project Title Principal Investigator Host OrganisationTotal Grant value

Pilot Manufacturing with Ultrafast Laser Plasma Implantation (ULPI)

Gin Jose University of Leeds £1.3 m

Manufacturing of nano-engineered III-N semiconductors

Philip Shields University of Bath £ 0.5 m

Materials for Healthcare Core

Materials for ICT Core

Materials for Demanding Environments Core

Materials for Energy Core

Space

Materials Discovery &

Development

Materials Sustainability

Reducing Lead times

Big Data

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Industrial Strategy Sectors

Resource Efficiency

Eight Great Technology

Links

Robotics

Synth. Bio

Advanced Materials Framework (draft)

Skills

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Research Nodes

GROWING INTEREST IN NEW INDUSTRIAL SYSTEMS

Re-Distributed Manufacturing

McKinsie Global InstituteMarket-Product Characteristics

Segment Key requirements Industry examples

Global innovation for local markets(34% of global value added)

Proximity to demandGovernment regulation and interventionAbility to innovateAccess to supply chains

Chemicals and pharmaceuticals

Transport equipment Machinery and

appliances

Regional processing(28% of global value added)

Access to raw materials and suppliersTransport costs and infrastructureProximity to demand

Rubber and plastics Fabricated metals Food and beverages Printing and publishing

Energy/resource-intensive commodities(22% of global value added)

Access to raw materialsProximity to demandTransport costs and infrastructureCost and availability of energy

Wood products Paper and pulp Basic metals Minerals-based products Oil, coal and nuclear

Global technologies/innovators(9% of global value added)

Ability to innovateLow labour costsAccess to supply chains

Computers Semi-conductors and

electronics Medical, precision and

optical equipment

Labour-intensive tradables(7% of global value added)

Low labour costsShort lead times to market

Textiles, apparel, leather Furniture Jewellery , toys

Characteristics of Future Manufacturing

Faster, more responsive and closer to customers

Exposed to new market opportunities

More sustainable

Increasingly dependent on highly skilled workers

Future Geography of Manufacturing

Driver Of particular relevance for for Potential spatialimplications

Narrowing of differentials in labour costs

Production activities offshored to take advantage of lower labour costs

Onshoring of some production activity to the UK

Higher transport costs Production activities offshored to take advantage of lower labour costs

Onshoring of some production activity to the UK

Need to be close to the market

Products customised to the market with short-term fashion cycles

Combination of manufacturing in high cost and low cost locations

Product quality concerns

All products, especially those where a premium is placed on quality

Onshoring of some activities

Theft of intellectual property

Product innovation, process innovation less easy to copy due to

tacit knowledge

Onshoring of activities where intellectual property is important

Economic downturn and reductions in sizeof orders

Large scale components orders from low cost locations

Opportunities for local suppliers willing to supply small batch

orders

Advantages of co-location of design, R&D and production

Spatially separated activities Greater co-location of activity in the UK and/ or outside the UK

Changing energy costs Energy-intensive activities Relocation to areas with low costs

Industrial StrategyStrengthening Supply Chains

Improve the performance and competitiveness of domestic supply chains:

Innovation

Skills

Access to finance

SME capability

Supply chain collaboration

Supply chain resilience

World Economic Forum: Distributed ManufacturingThe factory of the future is online – and on your doorstep

Distributed manufacturing turns on its head the way we make and distribute products. In traditional manufacturing, raw materials are brought together, assembled and fabricated in large centralized factories into identical finished products that are then distributed to the customer. In distributed manufacturing, the raw materials and methods of fabrication are decentralized, and the final product is manufactured very close to the final customer.

HOW DID WE GET TO HERE?Re-Distributed Manufacturing

Re-Distributed Manufacturing Workshop November 2013

Multidisciplinary and cross sector debate

Definition and scope

Explore potential research areas

Build a community

Develop shared understanding of future directions

Identify next steps

Technology, systems and strategies that change the economics and organisation of manufacturing,

…. particularly with regard to location and scale.

£3M for six multidisciplinary “agenda forming” networks

Re-DistributedManufacturing

Related themes

Personalised healthcare

Circular economy

Industrial symbiosis

Maker/crowd movements

Mass localisation

New design paradigms

Cloud manufacturing

Autonomous production

Manufacturing geographies

Building sustainable local nexuses of food, energy & water

Dr A YangUniversity of Oxford

Re-distributed manufacturing and the resilient, sustainable city

Prof Chris McMahonUniversity of Bristol

RECODE: Consumer goods, Big Data and re-distributed manufacturingDr Fiona Charnley, Cranfield University

Re-distributed manufacturing healthcare research

Dr Wendy PhilipsUniversity of the West of England

3DP-RDM: Defining the research agenda for 3D printing enabled re-distributed manufacturingDr Tim MinshallCambridge University

The role of makespaces in re-distributed manufacturing

Prof Sharon BaurleyRoyal College of Art

Re-Distributed Manufacturing NetworksTechnology, systems & strategies that change the economics and organisation of manufacturing ….

particularly with regard to location and scale.

LANGUAGE, CULTURE & CONTEXTSMULTI-DISCIPLINARITY AND TRANSLATION

Re-Distributed Manufacturing

Production & Fabrication

Simulation & Design

Systems & Enablers

Manufacturing Research

Fundamentals & Theory

Applications & Outcomes

The Research Council for Manufacturing

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MRC (including UK Regenerative Medicine Platform, Biomedical Catalyst, AMR)

EPSRC, BBSRC

Innovate UK, including Health KTN, Biomedical Catalyst, Cell Therapy & Precision Medicine

Catapult, Innovation Platforms (Stratified Medicine, Assisted Living )

National Centre for the Replacement Refinement and Reduction of Animals In Research (NC3Rs)

Wellcome Trust, Cancer Research UK

DoH, including NIHR HTCs, NHS England and AHSNs

Manufacturing Value Chain

Institute for Manufacturing, University of Cambridge

Physical Production Engineering Advanced Manufacturing Manufacturing Machines & Equipment Materials Process & Performance Control Fabrication & Processing Technology Advanced Processing & Packaging Production scale-up (emerging industries)

Decision Systems Engineering Reconfigurable Manufacturing Systems System Design & Simulation Engineering Product Development Innovation Visualizing & virtual prototyping systems Sensors and Sensing Systems Control Systems

Industrial Innovation Systems Innovation Systems & Design Eng Operations Systems research Logistics & Distribution Value chain research Product-service systems Industrial Organizational Systems

Applied science & Technology Materials science Device physics Applied chemistry Biotechnology

Industrial Systems-Market/Society Interface Innovation Systems & Design Service Enterprise Systems Industrial Economics Industrial policyECONOMIC &

SOCIAL SCIENCE

RESEARCH

APPLIED SCIENCE

RESEARCH

ENGINEERING RESEARCH

Industrial Innovation and Research Fields

(Eoin O’Sullivan, IfM Cambridge)

Identify

Societal / Market Needs& define system requirements & barriers

Develop Useful Insights from

Fundamental Knowledge

Integrate Fundamental Knowledge into

Enabling Technology

Research SystemsInteracting research activities

(E O’Sullivan: Adapted from NSF ERC Strategy Framework)

FINAL (CAUTIONARY) THOUGHTSRe-Distributed Manufacturing

Re-Distributed Manufacturing

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Re-Distributed Manufacturing

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