TKMC

Proudly presents………..

‘13 BATCH

HISTORY ROUND

RULES

Each Question Carries 10 Marks.

Each Team Will Be Given 1 Minute For EachQuestion In Sub Round 1 And 30 Seconds InSub Round 2.

30 + 30 Seconds To Identify The Picture AndAnswer The Question.

Question Passes To The Next Team IfUnanswered.

Such Answered Question Carries Half TheMark Allotted.

Question Cannot Be Passed In Sub Round 2 .

HISTORY ROUND

Identify the person

HISTORY ROUND

Identify the person

what is his contribution

on endocrinology?

HISTORY ROUND

Fredrick Grant Banting

Isolation & use of

insulin for the control of

carbohydrate

metabolism.

HISTORY ROUND

Who is this

personality?

HISTORY ROUND

Who is this personality?

What is his role onendocrinology?

HISTORY ROUND

THOMAS ADDISION

He has given the

details of

adrenocortical

deficiencies

HISTORY ROUND

Identify the person.

HISTORY ROUND

Identify the person.

What is Cushing’s

disease?

HISTORY ROUND

HARVEY WILLIAM

CUSHING

Excessive cortisol

secretion due to

increased pituitary

activity

HISTORY ROUND

Who worked on C Amp ?

EARL SUTHERLAND

HISTORY ROUND

Who introduced radio immunoassay for

the measurement of hormones ?

BERSON & YALOW

HISTORY ROUND

Who described about corticotropin

releasing factor ?

HISTORY ROUND

SUFFRAN & SCHALLY

HISTORY ROUND

Identify the person.

What is his work in

endocrinology?

HISTORY ROUND

WILLIAM MADDOCK BAYLISS

He demonstrated hormonal regulation of

pancreatic secretion.

FUNCTIONAL ANATOMY

Rules

Each question carries 5+5 = 10 marks.

20 + 20 seconds for identification and

answering the related question.

Should answer the first question to unlock

the 2nd question

No pass allowed.

FUNCTIONAL ANATOMY

Identify the picture.

FUNCTIONAL ANATOMY

Identify The Picture.

Why The Cells In The

Marked Zone Appear

Clear And

Homogenous .

FUNCTIONAL ANATOMY

Ans:

a. Histology of adrenal

gland

b. Because of

cholesterol

accumulation

FUNCTIONAL ANATOMY

a. Identify the picture.

FUNCTIONAL ANATOMY

a. Identify the picture.

b. Name the cells

present in the outer

zone

FUNCTIONAL ANATOMY

Ans:

a. Structure of islet of

langer hans

b. Alpha cells

FUNCTIONAL ANATOMY

a. Identify the picture.

FUNCTIONAL ANATOMY

a. Identify the picture.

b. Which is the

predominant cell

FUNCTIONAL ANATOMY

a. IDENTIFY THE

PICTURE.

b. WHICH IS THE

PREDOMINANT

CELL and WHAT IT

SECRETES.

FUNCTIONAL ANATOMY

Ans:

a. Histology of

parathyroid gland

b. Chief cells

,Parathormone

FUNCTIONAL ANATOMY

a. Identify the diagram.

FUNCTIONAL ANATOMY

a. Identify the diagram.

b. Who studied on

goitre about thyroid

dysfunction?

FUNCTIONAL ANATOMY

Ans:

a. Histology of thyroid

gland

b. Emil theodor kocher

FUNCTIONAL ANATOMY

Name the special type of supporting cells

of pituitary gland ?

FUNCTIONAL ANATOMY

Ans :- PITUICYTES

FUNCTIONAL ANATOMY

Adrenal medulla is derived from ?

FUNCTIONAL ANATOMY

Ans :- NEUROECTODERM

FUNCTIONAL ANATOMY

What is epiphysis cerebri ?

FUNCTIONAL ANATOMY

Ans :- PINEAL GLAND

BUZZER ROUND

Rules

Each question carries 10 marks

First team to press the buzzer will be

allowed to answer the question.

If the allowed team gives wrong answer

five marks will be reduced from their

score.

No pass allowed

BUZZER ROUND

What is acromicria?

BUZZER ROUND

What is Acromicria?

Growth horomone deficieny in adults

leads to atrophy of the extremities

BUZZER ROUND

SIMMONDS DISEASE ?

BUZZER ROUND

SIMMONDS DISEASE ?

Ans: PANHYPOPITUITARISM

BUZZER ROUND

What is medical adrenalectomy ?

BUZZER ROUND

What is medical adrenalectomy ?

Ans:

inhibition of cortisol synthesis by

administration of high dose of

ketakonazole of metyrapone

BUZZER ROUND

EXPLANATION OF IRM ASSAY IS

____________

BUZZER ROUND

EXPLANATION OF IRM ASSAY IS

____________

ANS: IMMUNO RADIOMETRIC ASSAY

BUZZER ROUND

WHICH IS AN INDEX OF BONE

RESORPTION

BUZZER ROUND

HYDROXYPROLINURIA

BUZZER ROUND

WHAT IS INCRETINS ?

BUZZER ROUND

What is incretins ?

Ans: gut hormones which stimulate insulin

secretion eg. Gip & glp -1

MCQ ROUND

Rules

Each question carries 5 marks.

Time allotted will be 1 minute

Passing not allowed.

MCQ ROUND

1. Insulin increases the entry of glucose into

A. Reneal tubular cells

B. The mucosa of the smal intestine

C. Most neurons in the cerebral cortex

D. Skeletal muscle

MCQ ROUND

1. Insulin increases the entry of glucose into

A. Reneal tubular cells

B. The mucosa of the smal intestine

C. Most neurons in the cerebral cortex

D. Skeletal muscle

MCQ ROUND

2. Which of the following are incorrectly

paired?

A. Free fatty acid mobilization :

dehydroepiandrosterone

B. Muscle glycogenolysis : epinephrine

C. Kaliuresis : aldosterone

D. Hepatic glycogenesis : insulin

MCQ ROUND

2. Which of the following are incorrectly

paired?

A. Free fatty acid mobilization :

dehydroepiandrosterone

B. Muscle glycogenolysis : epinephrine

C. Kaliuresis : aldosterone

D. Hepatic glycogenesis :insulin

MCQ ROUND

3. Which of the following hormones has the

shortest plasma half life?

A. Corticosterone

B. Dehydroepiandrostrone

C. Aldosterone

D. Norepinephrine

MCQ ROUND

3. Which of the following hormones has the

shortest plasma half life?

A. Corticosterone

B. Dehydroepiandrostrone

C. Aldosterone

D. Norepinephrine

MCQ ROUND

4. Which of the following is not involved in

regulating plasma ca2+ levels?

A. Kidneys

B. Skin

C. Liver

D. Lungs

MCQ ROUND

4. Which of the following is not involved in

regulating plasma ca2+ levels?

A. Kidneys

B. Skin

C. Liver

D. Lungs

MCQ ROUND

5. Which of the following is not characteristic

of hypopituitarism?

A. Cachexia

B. Infertility

C. Low basal metabolic rate

D. Intolerance to stress

MCQ ROUND

5 which of the following is not characteristic

of hypopituitarism?

A. Cachexia

B. Infertility

C. Low basal metabolic rate

D. Intolerance to stress

MCQ ROUND

6. 17-ketosteroids are all except

A. Androsterone

B. Ehocholanolone

C. Dhea-s

D. Corticosterone

MCQ ROUND

6. 17-ketosteroids are all except

A. Androsterone

B. Ehocholanolone

C. Dhea-s

D. Corticosterone

RECENT ADVANCES

Rules

Question carries 10 marks.

Time alloted will be 20 seconds

Passing allowed

If passed time will be reduced to 10

seconds.

Marks for the each passed question will

be 5

RECENT ADVANCES

DEIODINASES CONTAINS _______

TRACE ELEMENT

RECENT ADVANCES

DEIODINASES CONTAINS _______

TRACE ELEMENT

ANS: SELENIUM

RECENT ADVANCES

LEPTIN RECEPTOR IS LINKED TO ____

ENZYME ACTIVITY

RECENT ADVANCES

LEPTIN RECEPTOR IS LINKED TO ____

ENZYME ACTIVITY

ANS: TYROSINE KINASE

RECENT ADVANCES

PROLACTIN ACTIVATE _______

SIGNALLING PATHWAY

RECENT ADVANCES

PROLACTIN ACTIVATE _______

SIGNALLING PATHWAY

ANS: JAK / STAT PATHWAY

RECENT ADVANCES

POINT MUTATIONS IN INSULIN GENE

CAN BE DEFECTED BY _____

TECHNIQUE.

RECENT ADVANCES

POINT MUTATIONS IN INSULIN GENE

CAN BE DEFECTED BY _____

TECHNIQUE.

ANS: OLIGUNUCLEOTIDE PROBE

HYBRIDIZATION

RECENT ADVANCES

RADIO RECEPTOR ASSAY IS MAINLY

USEFUL IN MEASURING THE ACTIVITY

OF ____ HORMONE

RECENT ADVANCES

RADIO RECEPTOR ASSAY IS MAINLY

USEFUL IN MEASURING THE ACTIVITY

OF ____ HORMONE

ANS: 1-25- DIHYDROXY

CHOLECALCIFEROL

RECENT ADVANCES

PROHORMONE TO HORMONE

CONVERSION TAKES PLACE IN WHICH

INTRACELLULAR ORGANELLE?

RECENT ADVANCES

PROHORMONE TO HORMONE

CONVERSION TAKES PLACE IN WHICH

INTRACELLULAR ORGANELLE?

ANS: GOLGI APPARATUS

CASE SCENARIO

Rules

Each question carries 5 + 5 = 10 marks

Time alloted will be 90 seconds.

No passing allowed.

CASE SCENARIO

Identify the condition

CASE SCENARIO

a. Identify the condition

and the disease

causing this

b. Reason behind this

CASE SCENARIO

Ans

a. Hyperpigmentation due

to addisson’s

disease

b. Acth (msh) causes

hyper pigmentation

CASE SCENARIO

Identify the condition

CASE SCENARIO

Identify the marked

lesion

What will be the

visual deffect

produced.

CASE SCENARIO

Ans:

PITUITARY

ADENOMA.

Bitemporal

hemianopia

CASE SCENARIO

a. Identify the picture

CASE SCENARIO

a. Identify the picture

b. What is the O2

consumption in

hypothyroidism ?

CASE SCENARIO

Ans:

a. Multinodular goitre

b. 150ml/dl

CASE SCENARIO

a. Identify the sign and

condition causing

this

CASE SCENARIO

a. Identify the sign and

condition causing this

b. Lethal level of calcium and

mention about calcium

regulatory proteins

CASE SCENARIO

Ans:

a. Trousseau’s sign

hypocalcemic tetany

b. 4mg/dl ,

CALMODULIN AND

CALBINDIN

CASE SCENARIO

An eight year old child has pot belly,

delayed milestones and delayed eruption

of teeth .

1 identify the condition

2 what is the cause of the pot belly

Ans

Cretinism

Hypotonia of anterior abdominal wall

muscles

CASE SCENARIO

A male patient aged 40 years, complaint

of extreme weakness despite voracious

eating , had polyuria and polydipsia. ON

INVESTIGATION HIS BLOOD GLUCOSE

FOUND TO BE 220mg/dl.

1. Glycosylated hb determine the blood

glucose level over a period of ?

2. What is the cause for polyuria?

Ans

1) 6-8wks

2) osmotic diuresis

RUSH OR RELAX ROUND

Rules

Team will be given the choice to opt rush /relax question.

Marks for rush question is 20 marks in 10seconds

For incorrect rush answer 5 marks will bereduced from their score.

Marks for relax question is 10 marks in 45seconds

No negative for relax question.

RUSH

Plasma insulin level rise more rapidly by

ural glucose than iv glucose – true or

false

RUSH

Plasma insulin level rise more rapidly by

ural glucose than iv glucose –

Ans: true

RELAX

I am stimulated by low serum calcium, i

act through osteoblast and i bring down

phosphorus iam metabolised by kupfer

cells

Who am i ?

RUSH

Of all the three layers of adrenal cortex

which is not influenced by ACTH

RUSH

Of all the three layers of adrenal cortex

which is not influenced by ACTH

Ans :zona glomerulosa

RELAX

Sweating

Tachycardia

Headache

Hypertension

Hyperglycemia

Asthma

↑ Urinary vma

Who am i?

RUSH

Prostaglandis was discovered by von-

euler in secretion of which gland

RUSH

Prostaglandis was discovered by von-

euler in secretion of which gland

Ans : prostate gland

RELAX

Calogenic effect of thyroid hormones is

by inducing which enzyme

Diabetic keto acidosis is a state of

intracellular dehydration true or false

RUSH OR RELAX ROUND

Na+/K+ atpase \ INCREASED O2

CONSUMPTION

True

RUSH OR RELAX ROUND

Diabetic keto acidosis is a state of

intracellular dehydration

Ans: true

JUMBLED WORDS

RULES

EACH QUESTION CARRIES 10 + 10 = 20 MARKS.

THE GIVEN WORD WILL BE A JUMBLED MEDICAL TERMINOLOGY.

EACH TEAM WILL BE GIVEN 10 MARKS TO REARRANGE AND FIND THE WORD IN 30 SECONDS.

THE CLUE WILL BE GIVEN AT YOUR REQUEST OR BY THE END OF THE 30 SCONDS FOR WHICH 5MARKS WILL BE REDUCED.

TWO QUESTIONS RELATED TO THE MEDICAL TERM WILL BE ASKED (5+5=10)

EXAMPLE

PEST SOSO ORID

OSTEOPOROSIS

JUMBLED WORDS

GEM CAL YARO

JUMBLED WORDS

Hint:

PITUITARY GLAND

DISORDER

ACROMEGALY

JUMBLED WORDS

What happens to carbohydrate

metabolism in this condition

What happens to internal organs

JUMBLED WORDS

Ans:

Impaired glucose tolerance leading to

diabetes mellitus

Organomegaly

JUMBLED WORDS

HYT DROITS

MOR

JUMBLED WORDS

Hint:

MEDICAL EMERGENCY

OF THYROID GLAND

JUMBLED WORDS

THYROID STROM

JUMBLED WORDS

What symptoms does this condition

presents with?

What are the percipitating events ?

JUMBLED WORDS

Fever, tachycardia, circulatory collapse,

restlessness

Major trauma such as surgery or illness in

a hyper thyroid patient

JUMBLED WORDS

ROMED SONNY

CNS

JUMBLED WORDS

Hint:

“This condition results in sodium and

water retention”

JUMBLED WORDS

CONN’S SYNDROME

JUMBLED WORDS

Cause for this condition?

What happens to ph in this condition?

JUMBLED WORDS

TUMOR OR HYPERPLASIA OF ZONA

GLOMERULOSA (PRIMARY HYPER

ALDOSTERONISM)

METABOLIC ALKALOSIS (Ph INCREASES)

RAPID FIRE ROUND

Rules

Ten questions for each team.

Time alloted will be 90 seconds.

Each question carries 5 marks.

No negative marks

If answer is not known you can pass on to

next question.

RAPID FIRE ROUND

1. ACTH SECRETION IS MAX DURING

2. RECEPTORS FOR CALCITONIN IN BONE IS FOUND IN WHICH CELLS

3. SIADH IS ALSO CALLED AS

4. MAX NO. OF ISLETS OF LANGERHANS ARE SEEN IN

5. FIRST PROTIEN DETECTED TO POSSESS HORMONAL ACTIVITY

6. MOST IMPORTANT STIMULUS FOR SECRETION OF

ERYTHROPROTIEN SECRETION IS

7. MAJOR CATHECHOLAMINE FROM ADRENAL MEDULLA ?

8. NAME THE HORMONE RESPONSIBLE FOR SYMPTOMS OF

HYPOGLYCEMIA

9. BASAL METABOLIC RATE IS MAINLY REGULATED BY WHICH

HORMONE

10. 90% PLASMA CORTISOL IS BOUND TO

RAPID FIRE ROUND

1. ACTH SECRETION IS MAX DURING EARLY MORNING 6-8

2. RECEPTORS FOR CALCITONIN IN BONE IS FOUND IN WHICH CELLS

OSTEOCLAST

3. SIADH IS ALSO CALLED AS DILUTION SYNDROME

4. MAX NO. OF ISLETS OF LANGERHANS ARE SEEN IN TAIL OF

PANCREAS

5. FIRST PROTIEN DETECTED TO POSSESS HORMONAL ACTIVITY

INSULIN

6. MOST IMPORTANT STIMULANT FOR ERYTHROPROTIEN SECRETION

IS HYPOXIA

7. MAJOR CATHECHOLAMINE FROM ADRENAL MEDULLA ? ADRENALIN

8. NAME THE HORMONE RESPONSIBLE FOR SYMPTOMS OF

HYPOGLYCEMIA NOREPINEPHRINE

9. BASAL METABOLIC RATE IS MAINLY REGULATED BY WHICH

HORMONE THYROXINE

10. 90% PLASMA CORTISOL IS BOUND TO TRANSCORTIN

RAPID FIRE ROUND

1. GLUT – 6 ?

2. MAJOR ADRENAL SEX STEROIDS ARE

3. SOMATOSTATIN IS DERIVED FROM WHICH CELLS

4. ENDOGENOUS INSULIN PRODUCTION IS MEASURED BY

5. DAILY DIETRY REQUIREMENT OF CALCIUM IN A PREGNANT

WOMEN/DAY IS

6. DIABETIC KETOACIDOSIS IS A STATE OF INTRA-CELLULAR

DEHYDRATION TRUE OR FALSE

7. GROWTH HORMONE IS SYNTHESISED BY

8. ABSENCE OF GH RECEPTORS RESULTS IN WHICH CONDITION

9. HERRING’S BODIES ARE SEEN IN

10. MELATONIN SECRETION IS MAX DURING ?

RAPID FIRE ROUND

1. GLUT – 6 ? PSUEDOGENE

2. MAJOR ADRENAL SEX STEROIDS ARE (DHEA) ANDROSTENEDIONE

3. SOMETO STATIN IS DERIVED FROM WHICH CELLS DELTA CELL

4. ENDOGENOUS INSULIN PRODUCTION IS MEASURED BY C-PEPTIDE

5. DAILY DIETRY REQUIREMENT OF CALCIUM IN A PREGNANT

WOMEN/DAY IS 1500mg/day

6. DIABETIC KETOACIDOSIS IS A STATE OF INTRA-CELLULAR

DEHYDRATION TRUE OR FALSE

7. GROWTH HORMONE IS SYNTHESISED BY ARCUATE NUCLEUS

8. ABSENCE OF GH RECEPTORS RESULTS IN WHICH CONDITION

AFRICAN PYGMIES PWART

9. HERRING’S BODIES ARE SEEN IN POSTERIOR PITUITARY

10. MELATONIN SECRETION IS MAX DURING ? 11AM TO 7PM

RAPID FIRE ROUND

1. Physiological secretion of insulin stops at what level ofplasma glucose ?

2. Name the only hypoglycemic hormone?

3. What is pendrin ?

4. Renal threshold of blood glucose is

5. Precussor aminoacid for melatonin ?

6. Hyper secretion of thymin results in

7. Thromboxene a2 is systhesised by

8. Urinary vanillyl mandelic acid is elevated in whichcondition

9. Acidophillic cells or pituitary gland secrets

10. Somotomedin c10 also known as

RAPID FIRE ROUND

1. Physiological secretion of insulin stops at what level ofplasma glucose ? 90mg/dl

2. Name the only hypoglycemic hormone? Insulin

3. What is pendrin ? cl -/ i – exchanger

4. RENAL THRESHOLD OF BLOOD GLUCOSE IS180mg/dl

5. Precussor aminoacid for melatonin tryptophan

6. Hyper secretion of thymin results in myathenia gravis

7. Thromboxene a2 is systhesised by platelets

8. Urinary vanillyl mandilic acid is elevated in whichcondition phechromocytoma

9. Acidophillic cells or pituitary gland secrets gh/prolactin

10. Somotomedin c10 also known as igf-1