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NPL Management Ltd - Public Electron Beam Dosimetry at NPL Julia Snaith Practical Course in Reference Dosimetry 19 22 January 2016

Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

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Page 1: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Electron Beam Dosimetry at NPL

Julia Snaith

Practical Course in Reference Dosimetry

19 – 22 January 2016

Page 2: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Overview

• IPEM Code of Practice

– Theory

– Dose conversion

– Beam quality

– Phantoms

• Electron beam calorimeter

• Calibration of secondary standards

Covered in greater detail during

electron practical session

Page 3: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

The IPEM 2003 Code

of Practice

• 1989: NPL introduced

calorimeter-based protocols

for MV X-ray beams

• 1990: IPSM published

photon CoP based on this

• 1996: Air kerma based

electron protocol

• 2003: Calorimetry-based

protocol, referenced to

absorbed dose to water

Page 4: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

The IPEM 2003 Code

of Practice

• Based on the NPL absorbed

dose calibration service,

which gives direct factors for

electron chambers in terms

of absorbed dose to water

• A simple procedure to follow

in the clinic and a

significantly reduced

uncertainty

• Electron dosimetry now on

the same footing as MV

photons

Page 5: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Outline of Code

• Section 1: Introduction

• Section 2: Code of Practice

• Appendices:

– A – Corrections

– B – Chambers

– C – Formalism

– D – Data

– E – Uncertainties

Everything needed to measure

absorbed dose to water in an

electron beam is described in this

document

Page 6: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (1)

(1) define reference depth in water for beams at NPL

(2) use range scaling to get depth in graphite

(3) calibrate chamber against the calorimeter at NPL, in graphite, at

zref,g

ND

MD ref g

g

ref g

, ,

,

zref,g = zref,w R50,g / R50,w

zref = 0.6 R50,D – 0.1 cm

Page 7: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (2)

(4) theoretical conversion from graphite to water

N Np

p

s

sD ref w D ref g

ref w

ref g

w air

g air

, , , ,

,

,

/

/

(5) compare user and reference chambers at NPL, at zref,w in water

N NM

MD user w D ref w

ref w

user w

, , , ,

,

,

The formalism is described in detail in Appendix C.

Page 8: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (1)

(1) define reference depth in water for beams at NPL

(2) use range scaling to get depth in graphite

(3) calibrate chamber against the calorimeter at NPL, in graphite, at

zref,g

ND

MD ref g

g

ref g

, ,

,

zref,g = zref,w R50,g / R50,w

zref = 0.6 R50,D – 0.1 cm

Page 9: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(1) Reference depth zref = 0.6 R50,D – 0.1 cm

R100

depth in water, z/cmR85 R50 Rp

• Electron energy as a specifier

can be confusing – what does

it refer to?

• Mean energy emerging

from linac?

• Mean energy at phantom

surface?

• Choose R50,D as the specifier:

• Defines reference depth

• Calibration factors on the

NPL certificate given as a

function of R50,D

Page 10: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(1) Reference depth zref = 0.6 R50,D – 0.1 cmDepth-dose curves for NPL Clinical Linac

0

20

40

60

80

100

120

0 20 40 60 80 100 120

Depth,mm

Re

lati

ve d

os

e

4 MeV

6 MeV

8 MeV

10 MeV

12 MeV

15 MeV

18 MeV

20 MeV

22 MeV

Page 11: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(1) Reference depth zref = 0.6 R50,D – 0.1 cm

NPL

Royal London SL18

Edinburgh WG LA20

Mount Vernon SL20

Rogers SL75/20, 2100C, Therac 20

NKI SL75/20

NRC

R1

00

in w

ate

r (c

m)

R50 in water (cm)

Linear fit below R50 = 3.5cm: R100 = 0.60 R50 - 0.10

0 1 2 3 4 5 6 7 8 9

0

1

2

3

4

5

6 NPL

Royal London SL18

Edinburgh WG LA20

Mount Vernon SL20

Rogers SL75/20, 2100C, Therac 20

NKI SL75/20

NRC

R1

00

in w

ate

r (c

m)

R50 in water (cm)

Linear fit below R50 = 3.5cm: R100 = 0.60 R50 - 0.10

0 1 2 3 4 5 6 7 8 9

0

1

2

3

4

5

6

• Burns et al 1996

Page 12: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (1)

(1) define reference depth in water for beams at NPL

(2) use range scaling to get depth in graphite

(3) calibrate chamber against the calorimeter at NPL, in graphite, at

zref,g

ND

MD ref g

g

ref g

, ,

,

zref,g = zref,w R50,g / R50,w

zref = 0.6 R50,D – 0.1 cm

Page 13: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(2) Range scaling

• If the reference depth in graphite, zref,g, is chosen such that

• then the electron spectrum at the reference depth will be similar for

each phantom.

zref,g = zref,w R50,g / R50,w

Page 14: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (1)

(1) define reference depth in water for beams at NPL

(2) use range scaling to get depth in graphite

(3) calibrate chamber against the calorimeter at NPL, in graphite, at

zref,g

ND

MD ref g

g

ref g

, ,

,

zref,g = zref,w R50,g / R50,w

zref = 0.6 R50,D – 0.1 cm

Page 15: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(3) The NPL electron beam graphite calorimeter

Electron beam

Core

1mm air gaps

Backscatter plates

Buildup plates Kapton insulator

Page 16: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

The calorimeter core

• Disc 50mm diameter, 2mm thick

• Contains 2 bead thermistors

• Polystyrene sprung support

strips

• Octagonal plates near to the

core to minimise the effect of the

unirradiated ‘cold’ corners

Page 17: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Calibration of NPL transfer standard

chambers• Deliver 200MU alternately to calorimeter and chambers

• Use the calorimeter to determine Dose (Gy) / MU

• Use the chamber readings to measure Charge (C) / MU

• Combine these to determine chamber calibration factor:

Gy / C

Page 18: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Corrections to calorimeter dose

Dg = cg.∆Traw.funif.fgap.fdist.fdepth.fscat.fmat.fheat.fback

Page 19: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Corrections to the ion chamber reading

Mref,g = Mraw.fTP.funif.fdist.fdepth.fscat.fion.fpol.felec.fnon-lin.fback

Page 20: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (1)

(1) define reference depth in water for beams at NPL

(2) use range scaling to get depth in graphite

(3) calibrate chamber against the calorimeter at NPL, in graphite, at

zref,g

zref,g = zref,w R50,g / R50,w

zref = 0.6 R50,D – 0.1 cm

ND

MD ref g

g

ref g

, ,

,

Page 21: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (2)

(4) theoretical conversion from graphite to water

N Np

p

s

sD ref w D ref g

ref w

ref g

w air

g air

, , , ,

,

,

/

/

(5) compare user and reference chambers at NPL, at zref,w in water

N NM

MD user w D ref w

ref w

user w

, , , ,

,

,

The formalism is described in detail in Appendix C.

Page 22: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(4) Conversion from graphite to water

• The perturbation factors for the reference chamber (pref,w and

pref,g ), correct for the presence of the chamber in water and

graphite respectively

• sw/air and sg/air are the stopping power ratios of water and

graphite, respectively, to that of air for the spectrum at this

position.

N Np

p

s

sD ref w D ref g

ref w

ref g

w air

g air

, , , ,

,

,

/

/

Page 23: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

IPEM 2003 Theory (2)

(4) theoretical conversion from graphite to water

N Np

p

s

sD ref w D ref g

ref w

ref g

w air

g air

, , , ,

,

,

/

/

(5) compare user and reference chambers at NPL, at zref,w in water

N NM

MD user w D ref w

ref w

user w

, , , ,

,

,

The formalism is described in detail in Appendix C.

Page 24: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(5) Compare user and reference chambers

in water

• Calibration at 6 beam qualities

• Polarity and recombination measured at

each beam quality

N NM

MD user w D ref w

ref w

user w

, , , ,

,

,

M(zref) = Mraw.fTP.fion.fpol.felec

Page 25: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(

Page 26: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

(

Page 27: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

A few notes – non-water phantoms

• Calibration in a water phantom recommended

• Solid phantoms allowed, especially for low energy beams

(see Code of Practice section 2.2.8)

• Order of preference:

• 1. Water

• 2. Epoxy resin materials

• 3. PMMA, polystyrene

N.B. Uncertainties increase

Page 28: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Non-water phantoms

• Solid phantoms offer significant

advantages:

• Robust

• Dry!

• Mechanically stable

• Easy to set up

• but we need absorbed dose to

water

Page 29: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Non-water phantoms – Code of Practice 2.2.8

• Solid phantoms offer significant

advantages:

• Robust

• Dry!

• Mechanically stable

• Easy to set up

• but we need absorbed dose to

water

Page 30: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

A note on the recombination correction

• It is important that a chamber is operated in the linear region

1/V (V-1)

0.000 0.005 0.010 0.015 0.020 0.025 0.030 0.035

1/I (

no

rmalised

)

0.998

1.000

1.002

1.004

1.006

1.008

1.010

1.012

1.014

1.016

Page 31: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Overview

• IPEM Code of Practice

– Theory

– Dose conversion

– Beam quality specifier

• Electron beam calorimeter

• Calibration of secondary

standards

• Use in the clinic – covered in

next presentation

• Code of Practice – very

thorough

– You will need to read the

entire CoP to implement it

Covered in greater detail during

electron practical session

Page 32: Electron Beam Dosimetry at NPL · • Electron dosimetry now on the same footing as MV photons. NPL Management Ltd - Public Outline of Code • Section 1: Introduction • Section

NPL Management Ltd - Public

Electron practical session

• Gaining familiarity with the

IPEM 2003 Code of Practice

through both calculations and

measurements.

• Calculations:

• fluence scaling factor

• range scaling factor

• stopping power ratio

• determination of ND,w

• Measurements:

• beam quality

• beam output, including

corrections for ion

recombination and

polarity