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NPL Management Ltd - Public
Electron Beam Dosimetry at NPL
Julia Snaith
Practical Course in Reference Dosimetry
19 – 22 January 2016
NPL Management Ltd - Public
Overview
• IPEM Code of Practice
– Theory
– Dose conversion
– Beam quality
– Phantoms
• Electron beam calorimeter
• Calibration of secondary standards
Covered in greater detail during
electron practical session
NPL Management Ltd - Public
The IPEM 2003 Code
of Practice
• 1989: NPL introduced
calorimeter-based protocols
for MV X-ray beams
• 1990: IPSM published
photon CoP based on this
• 1996: Air kerma based
electron protocol
• 2003: Calorimetry-based
protocol, referenced to
absorbed dose to water
NPL Management Ltd - Public
The IPEM 2003 Code
of Practice
• Based on the NPL absorbed
dose calibration service,
which gives direct factors for
electron chambers in terms
of absorbed dose to water
• A simple procedure to follow
in the clinic and a
significantly reduced
uncertainty
• Electron dosimetry now on
the same footing as MV
photons
NPL Management Ltd - Public
Outline of Code
• Section 1: Introduction
• Section 2: Code of Practice
• Appendices:
– A – Corrections
– B – Chambers
– C – Formalism
– D – Data
– E – Uncertainties
Everything needed to measure
absorbed dose to water in an
electron beam is described in this
document
NPL Management Ltd - Public
IPEM 2003 Theory (1)
(1) define reference depth in water for beams at NPL
(2) use range scaling to get depth in graphite
(3) calibrate chamber against the calorimeter at NPL, in graphite, at
zref,g
ND
MD ref g
g
ref g
, ,
,
zref,g = zref,w R50,g / R50,w
zref = 0.6 R50,D – 0.1 cm
NPL Management Ltd - Public
IPEM 2003 Theory (2)
(4) theoretical conversion from graphite to water
N Np
p
s
sD ref w D ref g
ref w
ref g
w air
g air
, , , ,
,
,
/
/
(5) compare user and reference chambers at NPL, at zref,w in water
N NM
MD user w D ref w
ref w
user w
, , , ,
,
,
The formalism is described in detail in Appendix C.
NPL Management Ltd - Public
IPEM 2003 Theory (1)
(1) define reference depth in water for beams at NPL
(2) use range scaling to get depth in graphite
(3) calibrate chamber against the calorimeter at NPL, in graphite, at
zref,g
ND
MD ref g
g
ref g
, ,
,
zref,g = zref,w R50,g / R50,w
zref = 0.6 R50,D – 0.1 cm
NPL Management Ltd - Public
(1) Reference depth zref = 0.6 R50,D – 0.1 cm
R100
depth in water, z/cmR85 R50 Rp
• Electron energy as a specifier
can be confusing – what does
it refer to?
• Mean energy emerging
from linac?
• Mean energy at phantom
surface?
• Choose R50,D as the specifier:
• Defines reference depth
• Calibration factors on the
NPL certificate given as a
function of R50,D
NPL Management Ltd - Public
(1) Reference depth zref = 0.6 R50,D – 0.1 cmDepth-dose curves for NPL Clinical Linac
0
20
40
60
80
100
120
0 20 40 60 80 100 120
Depth,mm
Re
lati
ve d
os
e
4 MeV
6 MeV
8 MeV
10 MeV
12 MeV
15 MeV
18 MeV
20 MeV
22 MeV
NPL Management Ltd - Public
(1) Reference depth zref = 0.6 R50,D – 0.1 cm
NPL
Royal London SL18
Edinburgh WG LA20
Mount Vernon SL20
Rogers SL75/20, 2100C, Therac 20
NKI SL75/20
NRC
R1
00
in w
ate
r (c
m)
R50 in water (cm)
Linear fit below R50 = 3.5cm: R100 = 0.60 R50 - 0.10
0 1 2 3 4 5 6 7 8 9
0
1
2
3
4
5
6 NPL
Royal London SL18
Edinburgh WG LA20
Mount Vernon SL20
Rogers SL75/20, 2100C, Therac 20
NKI SL75/20
NRC
R1
00
in w
ate
r (c
m)
R50 in water (cm)
Linear fit below R50 = 3.5cm: R100 = 0.60 R50 - 0.10
0 1 2 3 4 5 6 7 8 9
0
1
2
3
4
5
6
• Burns et al 1996
NPL Management Ltd - Public
IPEM 2003 Theory (1)
(1) define reference depth in water for beams at NPL
(2) use range scaling to get depth in graphite
(3) calibrate chamber against the calorimeter at NPL, in graphite, at
zref,g
ND
MD ref g
g
ref g
, ,
,
zref,g = zref,w R50,g / R50,w
zref = 0.6 R50,D – 0.1 cm
NPL Management Ltd - Public
(2) Range scaling
• If the reference depth in graphite, zref,g, is chosen such that
• then the electron spectrum at the reference depth will be similar for
each phantom.
zref,g = zref,w R50,g / R50,w
NPL Management Ltd - Public
IPEM 2003 Theory (1)
(1) define reference depth in water for beams at NPL
(2) use range scaling to get depth in graphite
(3) calibrate chamber against the calorimeter at NPL, in graphite, at
zref,g
ND
MD ref g
g
ref g
, ,
,
zref,g = zref,w R50,g / R50,w
zref = 0.6 R50,D – 0.1 cm
NPL Management Ltd - Public
(3) The NPL electron beam graphite calorimeter
Electron beam
Core
1mm air gaps
Backscatter plates
Buildup plates Kapton insulator
NPL Management Ltd - Public
The calorimeter core
• Disc 50mm diameter, 2mm thick
• Contains 2 bead thermistors
• Polystyrene sprung support
strips
• Octagonal plates near to the
core to minimise the effect of the
unirradiated ‘cold’ corners
NPL Management Ltd - Public
Calibration of NPL transfer standard
chambers• Deliver 200MU alternately to calorimeter and chambers
• Use the calorimeter to determine Dose (Gy) / MU
• Use the chamber readings to measure Charge (C) / MU
• Combine these to determine chamber calibration factor:
Gy / C
NPL Management Ltd - Public
Corrections to calorimeter dose
Dg = cg.∆Traw.funif.fgap.fdist.fdepth.fscat.fmat.fheat.fback
NPL Management Ltd - Public
Corrections to the ion chamber reading
Mref,g = Mraw.fTP.funif.fdist.fdepth.fscat.fion.fpol.felec.fnon-lin.fback
NPL Management Ltd - Public
IPEM 2003 Theory (1)
(1) define reference depth in water for beams at NPL
(2) use range scaling to get depth in graphite
(3) calibrate chamber against the calorimeter at NPL, in graphite, at
zref,g
zref,g = zref,w R50,g / R50,w
zref = 0.6 R50,D – 0.1 cm
ND
MD ref g
g
ref g
, ,
,
NPL Management Ltd - Public
IPEM 2003 Theory (2)
(4) theoretical conversion from graphite to water
N Np
p
s
sD ref w D ref g
ref w
ref g
w air
g air
, , , ,
,
,
/
/
(5) compare user and reference chambers at NPL, at zref,w in water
N NM
MD user w D ref w
ref w
user w
, , , ,
,
,
The formalism is described in detail in Appendix C.
NPL Management Ltd - Public
(4) Conversion from graphite to water
• The perturbation factors for the reference chamber (pref,w and
pref,g ), correct for the presence of the chamber in water and
graphite respectively
• sw/air and sg/air are the stopping power ratios of water and
graphite, respectively, to that of air for the spectrum at this
position.
N Np
p
s
sD ref w D ref g
ref w
ref g
w air
g air
, , , ,
,
,
/
/
NPL Management Ltd - Public
IPEM 2003 Theory (2)
(4) theoretical conversion from graphite to water
N Np
p
s
sD ref w D ref g
ref w
ref g
w air
g air
, , , ,
,
,
/
/
(5) compare user and reference chambers at NPL, at zref,w in water
N NM
MD user w D ref w
ref w
user w
, , , ,
,
,
The formalism is described in detail in Appendix C.
NPL Management Ltd - Public
(5) Compare user and reference chambers
in water
• Calibration at 6 beam qualities
• Polarity and recombination measured at
each beam quality
N NM
MD user w D ref w
ref w
user w
, , , ,
,
,
M(zref) = Mraw.fTP.fion.fpol.felec
NPL Management Ltd - Public
(
NPL Management Ltd - Public
(
NPL Management Ltd - Public
A few notes – non-water phantoms
• Calibration in a water phantom recommended
• Solid phantoms allowed, especially for low energy beams
(see Code of Practice section 2.2.8)
• Order of preference:
• 1. Water
• 2. Epoxy resin materials
• 3. PMMA, polystyrene
N.B. Uncertainties increase
NPL Management Ltd - Public
Non-water phantoms
• Solid phantoms offer significant
advantages:
• Robust
• Dry!
• Mechanically stable
• Easy to set up
• but we need absorbed dose to
water
NPL Management Ltd - Public
Non-water phantoms – Code of Practice 2.2.8
• Solid phantoms offer significant
advantages:
• Robust
• Dry!
• Mechanically stable
• Easy to set up
• but we need absorbed dose to
water
NPL Management Ltd - Public
A note on the recombination correction
• It is important that a chamber is operated in the linear region
1/V (V-1)
0.000 0.005 0.010 0.015 0.020 0.025 0.030 0.035
1/I (
no
rmalised
)
0.998
1.000
1.002
1.004
1.006
1.008
1.010
1.012
1.014
1.016
NPL Management Ltd - Public
Overview
• IPEM Code of Practice
– Theory
– Dose conversion
– Beam quality specifier
• Electron beam calorimeter
• Calibration of secondary
standards
• Use in the clinic – covered in
next presentation
• Code of Practice – very
thorough
– You will need to read the
entire CoP to implement it
Covered in greater detail during
electron practical session
NPL Management Ltd - Public
Electron practical session
• Gaining familiarity with the
IPEM 2003 Code of Practice
through both calculations and
measurements.
• Calculations:
• fluence scaling factor
• range scaling factor
• stopping power ratio
• determination of ND,w
• Measurements:
• beam quality
• beam output, including
corrections for ion
recombination and
polarity