Sheet1Brand NameManufacturerGeneric NameDrug GroupEffect on VoiceAccolateZenecaZafirlukastantiasthmaticNo effects on voice or speech mechanisms have been reported.AccuprilParke-DavisQuinaprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorAcetaminophen/variousAcetaminophen/narcotic analgesicNarcotics may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to narcotic use.CodeineCodeineAdalat CCBayer PharmNifedipinecardiovascular -No effects on voice or speech mechanisms have been reported.calcium channel blockerAdderallShire RchwdAmphetaminecentral nervousAdderall may have a drying effect on vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.Mixed Saltssystem stimulantAlbuterolvariousAlbuterolantiasthmatic/Inhaled bronchodilators sometimes dry or irritate tissues in the mouth and throat and may lead to hoareseness, soreness, voice changes or laryngititis. Dry vocal tissues may be more prone to injuries, such as nodules, as well.AerosolbronchodilatorAlesse 28Wyeth-AyerstLevonorgestrel/hormoneThe use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveAllegraHoech Mar RFexofenadineantihistamineAntihistamines have a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules.AllopurinolvariousAllopurinolantigoutNo effects on voice or speech mechanisms have been reported.AlprazolamvariousAlprazolamantianxiety/Less than 1% of patients who take benzodiazepines experience slurred speech and symptoms of dysarthria (slow, uncoordinated speech).benzodiazepineAltaceHoech Marion RousselRamiprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorAmarylHoech Mar RGlimepirideantidiabeticNo effects on voice or speech mechanisms have been reported.AmbienSearleZolpidemsedative/The use of sedatives may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to sedative use.hypnoticAmitriptylinevariousAmitriptylinetricyclicTricyclic antidepressants may affect coordination, including the speech production system. Slow or slurred speech may be observed. They also have a drying effect on vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.antidepressantAmoxicillinvariousAmoxicillinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.AriceptEisaiDonepezilcholinergic function enhancer for Alzheimer's patientsInfrequent voice and speech effects may include include tongue edema, pharyngitis and bronchitis.ArthrotecSearleDiclofenac/nonsteroidal anti-inflammatoryThose who use their voices rigorously should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.MisoprostolAtenololvariousAtenololcardiovascular -No effects on voice or speech mechanisms have been reported.beta blockerAtrovent InhalerBoehringer lngelheimIpratropiumantiasthmatic/Inhaled antiasthmatic medications sometimes dry or irritate tissues in the mouth and throat and may lead to hoareseness, soreness, voice changes or laryngititis. Dry vocal tissues may be more prone to injuries, such as nodules, as well.antiallergyAugmentinSmithKline BeechamAmoxicillin/antibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.ClavulanateAvaproBristol-Myers SquibbIrbesartanACE InhibitorAlthough excessive coughing has been associated with the use of ACE inhibitors, which may lead to hoarseness and possible vocal tissue damage, this effect has NOT been associated with Avapro.AxidLillyNizatidinegastrointestinalTwo effects exist: 1) the antihistamine component has a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules; 2) however, this medication may benefit the voice if it is taken to reduce gastro-esophageal reflux. Uncontrolled spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.H2 antihistamineAzmacortRhn-Plnc RrTriamcinoloneantiasthmatic/Patients using inhaled steroids sometimes experience significant voice changes (including complete loss of voice). The onset of symptoms and severity of symptoms is highly variable among patients. Studies show that discontinuation of inhaled steroids restores the voice in dysphonic patients, but symptoms may not resolve immediately.aerosolsteroid (inhaled)BactrobanSmithKline BeechamMupirocintopical antibacterialNo effects on voice or speech mechanisms have been reported.BiaxinAbbottClarithromycinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.BuSparBristol-MyersBuspironeantianxietyNo effects on voice or speech mechanisms have been reported.SquibbCardizem CDHoech Mar RDiltiazemcardiovascular -No effects on voice or speech mechanisms have been reported.calcium channel blockerCarduraPfizerDoxazosincardiovascular -No effects on voice or speech mechanisms have been reported.alpha blockerCarisoprodolvariousCarisoprodolmuscle relaxantThe use of sedatives may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to sedative use.CeftinGlaxo WellcomeCefuroximeantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.CefzilBristol-Myers SquibbCefprozilantibioticCelexaForest PharmCitalopramantidepressantIncreased cough and gastroesophageal reflux have been reported, both of which can adversely affect the voice. Rarely, asthma, laryngitis, bronchospasm or sputum increase may occur.CephalexinvariousCephalexinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.CimetidinevariousCimetidinegastrointestinal -Two effects exist: 1) the antihistamine component has a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules; 2) however, this medication may benefit the voice if it is taken to reduce gastro-esophageal reflux. Uncontrolled spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.H2 antihistamineCiproBayer PharmCiprofloxacinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.Claritin, Claritin D 12HR, Claritin D 24HRScheringLoratadine orantihistamineAntihistamines have a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules.Loratidine/PseudoephedrineClimaraBerlexEstradiolhormone - estrogen/No effects on voice or speech mechanisms have been reported.topicalClonazepamvariousClonazepamanticonvulsantAnticonvulsants may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to their use.ClonidinevariousClonidineantihypertensiveNo effects on voice or speech mechanisms have been reported.CombiventBoehr IngelIpratropium/antiasthmatic/Inhaled bronchodilators sometimes dry or irritate tissues in the mouth and throat and may lead to hoareseness, soreness, voice changes or laryngititis. Dry vocal tissues may be more prone to injuries, such as nodules, as well.AlbuterolbronchodilatorCoumadinDupontWarfarinanticoagulantVocal performers, particularly, should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.CozaarMerckLosartancardiovascularAn infrequently-reported adverse reaction is coughing, which in turn, may cause hoarseness and possible vocal tissue damage.angiotension II antagonistCyclobenzaprinevariousCyclobenzaprinemuscle relaxantThe use of sedatives may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to sedative use. This medication may also have a drying effect on vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.CycrinESI LederleMedroxy-hormone -No effects on voice or speech mechanisms have been reported.progesteroneprogestinDayproSearleOxaprozinnonsteroidalVocal performers, particularly, should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.antiinflammatoryDeltasonePharmacia/Prednisoneantiinflammatory/Deltasone's effect is advantageous when used to shrink swollen vocal tissues, although patients taking Deltasone should be carefully monitored by a physician. It is not advised for patients with vocal fold ulcers, hemorrhages, or acute laryngitis.UpjohnsteroidDepakoteAbbottDivalproexanticonvulsantAnticonvulsants may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to their use.DesogenOrganonDesogestrelhormone -The use of oral contraceptives has not been shown to significantly affect female voices./EthinylEstradioloral contraceptiveDiazepamvariousDiazepamantianxiety/Less than 1% of patients who take benzodiazepines experience slurred speech and symptoms of dysarthria (slow, uncoordinated speech).benzodiazepineDiflucanPfizerFluconazoleantifungalNo effects on voice or speech mechanisms have been reported.DilantinParke-DavisPhenytoinanticonvulsantSlurred speech and other speech coordination tasks are possible adverse reactions to Dilantin use.DiovanNovartisValsartancardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorDyazideSmithKline BeechamHydrochlorothiazide/diuretic combinationDiuretics have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.TriamterineEffexorWyeth-AyerstVenlafaxineantidepressantEffexor may have a drying effect on the body, including vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.EloconScheringMometasonetopical steroidNo effects on voice or speech mechanisms have been reported.EndocetEndoOxycodone/APAPnarcotic analgesicNarcotics may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to narcotic use.Ery-TabAbbottErythromycinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.EstraceB-M SquibbEstradiolhormone - estrogenNo effects on voice or speech mechanisms have been reported.EstradermNovartisEstradiolhormone - estrogen/No effects on voice or speech mechanisms have been reported.patchEstradiolvariousEstradiolhormone - estrogenNo effects on voice or speech mechanisms have been reported.FlomaxAbbottTamsulosinbenign prostatic hypertrophy agentRarely, use of Flomax may cause pharyngitis or increased cough. Excessive coughing may lead to hoarseness and possible vocal tissue damage.FlonaseGlaxo WellcomeFluticasonesteroid decongestantThroat irritation and dryness, cough, hoarseness and voice changes are all possible adverse reactions.(nasal spray)FloventGlaxo WellcomeFluticasonesteroid decongestantPropionate(oral)Folic AcidScheinFolic AcidVitamin/mineral supplementNo effects on voice or speech mechanisms have been reported.FosamaxMerckAlendronateosteoporosis agentNo effects on voice or speech mechanisms have been reported.FurosemidevariousFurosemideloop diureticDiuretics have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.GemfibrozilvariousGemfibrozilantihyperlipidemicNo effects on voice or speech mechanisms have been reported.GlipizidevariousGlipizideantidiabeticNo effects on voice or speech mechanisms have been reported.GlucophageB-M SquibbMetforminantidiabeticNo effects on voice or speech mechanisms have been reported.Glucotrol XLPfizerGlipizideantidiabeticNo effects on voice or speech mechanisms have been reported.GlyburidevariousGlyburideantidiabeticNo effects on voice or speech mechanisms have been reported.GuaifenesinvariousGuaifenesinexpectorantGuaifenesin may have a beneficial effect on vocal tissues, as it helps keep vocal folds well-hydrated when used with plenty of water intake.Humulin 70/30,LillyHuman InsulinantidiabeticNo effects on voice or speech mechanisms have been reported.Humulin N,Humulin RHydro-variousHydrochlorothiazidethiazide diureticDiuretics have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.chlorothiazideHydrocodone w/APAPvariousHydrocodone w/APAPnarcotic analgesicNarcotics may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to narcotic use.HytrinAbbottTerazosincardiovascular -No effects on voice or speech mechanisms have been reported.alpha blockerHyzaarMerckLosartan/HCTZcardiovascular -Two adverse reactions are possible: 1) excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage; and 2) the diuretic component may have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.ACE inhibitorthiazide diureticIbuprofenvariousIbuprofennonsteroidalVocal performers, particularly, should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.anti-inflammatoryImitrexGlaxo WellcomeSumatriptanantimigrainous agentNo effects on voice or speech mechanisms have been reported.IsosorbidevariousIsosorbide MononitrateantianginalVoice-related effects may occur, including vocal tissue dryness (which, in addition to irritation effects, may be more prone to injuries, such as nodules). Bronchitis, bronchospasm and pharyngitis are other possible effects.MononitrateK-Dur-20ScheringPotassium Chloridepotassium supplementNo effects on voice or speech mechanisms have been reported.Klor-ConUpsher-SmithPotassium Chloridepotassium supplementNo effects on voice or speech mechanisms have been reported.LamisilNovartisTerbinafineantifungalNo effects on voice or speech mechanisms have been reported.LanoxinGlaxo WellcomeDigoxincardiovascular - inotropicNo effects on voice or speech mechanisms have been reported.LasixHoech Mar RFurosemideloop diureticDiuretics have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.LescolNovartisFluvastatinantihyperlipidemicNo effects on voice or speech mechanisms have been reported.LevaquinOrtho PharmLevofloxacinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.LevoxylJones PharmaLevothyroxinehormone - thyroidNo effects on voice or speech mechanisms have been reported.LipitorParke-DavisAtorvastatinantihyperlipidemicNo effects on voice or speech mechanisms have been reported.Lo/Ovral 28Wyeth-AyerstNorgestrel/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveLoestrin-Parke-DavisNorethindrone/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.FE 1.5/30Ethinyl Estradioloral contraceptiveLoestrin-Parke-DavisNorethindrone/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Fe 1/20Ethinyl Estradioloral contraceptiveLorabidLillyLoracarbefantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.LorazepamvariousLorazepamantianxiety/Less than 1% of patients who take benzodiazepines experience slurred speech and symptoms of dysarthria (slow, uncoordinated speech).benzodiazepineLotensinNovartisBenazeprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorLotrelNovartisAmlodipine/cardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.Benazeprilcalcium channel blocker/ACE inhibitorLotrisoneScheringClotrimoxazole/topical antifungalNo effects on voice or speech mechanisms have been reported.BetamethasoneMacrobidProcter & GambleNitrofurantoinantibacterialIn general, no effects on voice or speech mechanisms are associated with its use. It should be noted, however, that abuse of this agent can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.MedroxyvariousMedroxyhormone -No effects on voice or speech mechanisms have been reported.progesteroneprogesteroneprogestinMethylvariousMethylantiinflammatory/Methyl prednisolone's effects are beneficial when used to shrink swollen vocal tissues, although patients taking it should be carefully monitored by a physician. It is not advised for patients with vocal fold ulcers, hemorrhages, or acute laryngitis.prednisoloneprednisolonesteroidMetoprololvariousMetoprololcardiovascular -No effects on voice or speech mechanisms have been reported.Tartratebeta blockerMevacorMerckLovastatinantihyperlipidemicNo effects on voice or speech mechanisms have been reported.MiacalcinNovartisCalcitoninosteoporosis agentNo effects on voice or speech mechanisms have been reported.NasalSalmonMonoprilBristol-Myers SquibbFosinoprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorNaproxenvariousNaproxennonsteroidalVocal performers, particularly, should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.antiinflammatoryNasonexScheringMometasonesteroid decongestant nasal sprayThroat irritation and dryness, cough, hoarseness and voice changes are all possible adverse reactions. Rarely, oral or nasal candidiasis may occur.Necon 1/35Watson LabNorethindrone/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveNeomycin/variousNeomycin/topical antibiotic -No effects on voice or speech mechanisms have been reported.Polymx/HCPolymx/HCsteroid comboNeurontinParke-DavisGabapentinanticonvulsantNeurotonin may have a drying effect on the body, including vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.NitrostatParke-DavisNitroglycerinantianginalNo effects on voice or speech mechanisms have been reported.NorvascPfizerAmlodipinecardiovascular -No effects on voice or speech mechanisms have been reported.calcium channel blockerOrtho Tri-CyclenOrtho PharmNorgestimate/hormoneThe use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveOrtho-CeptOrtho PharmDesogestrel/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveOrtho-CyclenOrtho PharmNorgestimate/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveOrtho-Novum 7/7/7Ortho PharmNorethindrone/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveOxycodone/MallinckrodtOxycodone/APAPanalgesicNo effects on voice or speech mechanisms have been reported.AcetaminophenOxycontinPurdueOxycodoneanalgesicNo effects on voice or speech mechanisms have been reported.PaxilSmithKline BeechamParoxetineantidepressantPaxil may have a drying effect on the body, including vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.Penicillin VKvariousPenicillin VKantiboticNo effects on voice or speech mechanisms have been reported.PepcidMerckFamotidinegastrointestinal -Pepcid has a favorable effect on the voice in that it reduces esophageal reflux. Uncontrolled spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.H2 antagonistPhenergan SuppWyeth-AyerstPromethazineantihistamineAntihistamines have a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules.PlavixSanofiClopidogrelplatelet aggregation inhibitorThose who use their voices rigorously should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage. Bronchitis and coughing may occur; excess coughing may lead to hoarseness and possible vocal tissue damage.PlendilAstraFelodipine SRcardiovascularNo effects on voice or speech mechanisms have been reported.calcium channel blockerPotassiumvariousPotassiumpotassium supplementNo effects on voice or speech mechanisms have been reported.ChlorideChloridePravacholB-M SquibbPravastatinantihyperlipidemicNo effects on voice or speech mechanisms have been reported.PrednisonevariousPrednisoneantiinflammatory/Prednisone's effect is beneficial when used to shrink swollen vocal tissues, although patients taking it must be carefully monitored by a physician. It is not advised for patients with vocal fold ulcers, hemorrhages, or acute laryngitis.steroidPremarinWyeth-AyerstConjugated Estrogenshormone - estrogenNo effects on voice or speech mechanisms have been reported.PremproWyeth-AyerstConj. Estrogens/hormone -No effects on voice or speech mechanisms have been reported.Medroxyprogesteroneestrogen/progestinPrevacidTap PharmLansoprazolegastrointestinal -These agents have a favorable effect on the voice in that they reduce esophageal reflux. Uncontrolled spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.antisecretoryPrilosecAstraOmeprazolegastrointestinal -antisecretoryPrinivilMerckLisinoprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorProcardia XLPfizerNifedipinecardiovascular -No effects on voice or speech mechanisms have been reported.calcium channel blockerPromethazinevariousPromethazineantihistamineAntihistamines have a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules.tabsPropacet 100Teva PharmPropoxyphenenarcotic analgesicNarcotics may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to narcotic use.N/APAPPropoxyphenevariousPropoxyphenenarcotic analgesicN/APAPN/APAPPropranolol LAvariousPropranolol LAcardiovascular -No effects on voice or speech mechanisms have been reported.beta blockerPropulsidJanssenCisapridegastrointestinal stimulantNo effects on voice or speech mechanisms have been reported.ProveraPharmacia/Medroxyhormone -No effects on voice or speech mechanisms have been reported.UpjohnprogesteroneprogestinProzacLillyFluoxetineantidepressantProzac may have a drying effect on the body, including vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.RanitidinevariousRanitidinegastrointestinalTwo effects exist: 1) the antihistamine component has a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules; 2) however, this medication may benefit the voice if it is taken to reduce gastro-esophageal reflux. Uncontrolled spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.H2 antihistamineRelafenSmithKline BeechamNabumetonenonsteroidalVocal performers, particularly, should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.anti-inflammatoryRetin-AOrtho DermTretinointopical acne agentNo effects on voice or speech mechanisms have been reported.RezulinParke-DavisTroglitazoneantidiabeticNo effects on voice or speech mechanisms have been reported.RhinocortAstraBudesonidesteroid nasal sprayThroat irritation and dryness, cough, hoarseness and voice changes are all possible adverse reactions. Rarely, oral or nasal candidiasis may occur.RisperdalJanssenRisperidoneantipsychoticRisperdal may have adverse effects on speech, including difficulty in articulating words.RoxicetRoxaneOxycodone/APAPnarcotic analgesicNarcotics may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to narcotic use.SereventGlaxo WellcomeSalmeterolantiasthmatic/Inhaled bronchodilators sometimes dry or irritate tissues in the mouth and throat and may lead to hoareseness, soreness, voice changes or laryngititis. Dry vocal tissues may be more prone to injuries, such as nodules, as well.bronchodilatorSerzoneBristol-MyersNefazodoneantidepressantNo effects on voice or speech mechanisms have been reported.SquibbSingulairScheinMontelukastantiasthmatic maintenanceNo effects on voice or speech mechanisms have been reported.SumycinApotheconTetracycline HCLantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.SynthroidKnollLevothyroxinehormone - thyroidNo effects on voice or speech mechanisms have been reported.TamoxifenvariousTamoxifenantineoplastic/No effects on voice or speech mechanisms have been reported.antiestrogenTemazepamvariousTemazepamhypnotic/The use of sedatives may produce an uninhibited or diminished drive to speak. Symptoms of dysarthria (slow, slurred and uncoordinated speech movements) may also be linked to sedative use.benzodiazepineTiazacForestDiltiazemcardiovascular-calcium channel blockerNo effects on voice or speech mechanisms have been reported.Timoptic XEMerckTimololantiglaucoma agentNo effects on voice or speech mechanisms have been reported.TobradexAlcon LabTobramycin/ophthalmicNo effects on voice or speech mechanisms have been reported.Dexamethasoneantibiotic dropToprol-XLAstraMetoprololcardiovascular -No effects on voice or speech mechanisms have been reported.beta blockerTrazodoneSidmakTrazodoneantidepressantNo effects on voice or speech mechanisms have been reported.Tri-LevlenBerlexL-Norgestrel/hormone -The use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveTriamterene/variousTriamterene/diuretic combinationDiuretics have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.HCTZHCTZTrimethoprim/variousTrimeth/SulfamethantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.SulfaTrimoxApotheconAmoxicillinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush..TriphasilWyeth-AyerstL-Norgestrel/hormoneThe use of oral contraceptives has not been shown to significantly affect female voices.Ethinyl Estradioloral contraceptiveUltramMcNeilTramadolanalgesicNo effects on voice or speech mechanisms have been reported.Vancenase AQ DSScheringBeclomethasonenasal decongestantSore throat, cough, and rarely, perforation of the nasal septum, are possible adverse effects.VasotecMerckEnalaprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorVeetidsApotheconPenicillin VKantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.Verapamil SRvariousVerapamilcardiovascular -No effects on voice or speech mechanisms have been reported.calcium channel blockerViagraPfizerSildenafil Citrateperipheral vasodilatorNo effects on voice or speech mechanisms have been reported.VioxxMerckRofecoxibnonsteroidal anti-inflammatoryInfrequently, this agent may cause acid reflux or cough, both of which may lead to vocal tissue damage.WarfarinBarrWarfarinanticoagulantVocal performers, particularly, should be cautious about using medications that decrease platelet function during periods of strenous voicing demands, due to an increased possibility of vocal fold hemorrhage.Wellbutrin SRGlaxo WellcomeBupropion HCLantidepressantNo effects on voice or speech mechanisms have been reported.XalatanPharmacia/Latanoprostantiglaucoma agentNo effects on voice or speech mechanisms have been reported.UpjohnXanaxPharmacia/Alprazolamantianxiety/Less than 1% of patients who take benzodiazepines experience slurred speech and symptoms of dysarthria (slow, uncoordinated speech).UpjohnbenzodiazepineZantacGlaxo WellcomeRanitidinegastrointestinalTwo effects exist: 1) the antihistamine component has a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules. 2) however, this medication may benefit the voice if it is taken to reduce gastro-esophageal reflux. Uncontrolled spillage of stomach acids into the larynx is harmful to delicate vocal fold tissues.H2 antihistamineZestoreticZenecaLisinopril/HCTZcardiovascular -Two adverse reactions are possible: 1) excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage; and 2) the diuretic component may have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.antihypertensiveZestrilZenecaLisinoprilcardiovascular -Excessive coughing has been associated with the use of ACE inhibitors, which in turn, may lead to hoarseness and possible vocal tissue damage.ACE inhibitorZiacWyeth-Bisoprolol/HCTZcardiovascular -Diuretics have a drying effect on mucous membranes, including those used for speaking and singing. Hoarseness, sore throat, voice changes or laryngitis are possible symptoms. In addition to irritation effects, dry vocal folds may be more prone to injuries, such as nodules.AyerestantihypertensiveZithromax andPfizerAzithromycinantibioticIn general, no effects on voice or speech mechanisms are associated with antibiotic use. It should be noted, however, that antibiotic abuse can lead to an overgrowth of candida in the body, possibly leading to laryngeal thrush.Zithromax SuspZocorMerckSimvastatinantihyperlipidemicNo effects on voice or speech mechanisms have been reported.ZoloftPfizerSertralineantidepressantZoloft may have a drying effect on the body, including vocal fold tissues, which can lead to hoarseness, soreness, voice changes or laryngitis. Additionally, dry vocal tissues may be more prone to injuries such as nodules.ZybanGlaxo WellcomeBupropion HCL SRantidepressantNo effects on voice or speech mechanisms have been reported.ZyprexaLillyOlanzapinepsychotropic agentInfrequent effects may include coughing, pharyngitis, or (non-defined) voice alteration.ZyrtecPfizerCetirizineantihistamineAntihistamines have a drying effect on mucous membranes that may cause hoarseness, sore throat, voice changes or laryngitis. In addition to irritation, dry vocal folds may be more prone to injuries, such as nodules.

Sheet2

Sheet3