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Editorial Image Processing in Ophthalmology Robert Koprowski , 1 Anna Nowińska, 2 Sławomir Wilczynski, 3 Michele Lanza , 4 Vasyl Molebny, 5 and Renato Ambrosio Jr. 6,7,8,9,10 1 Department of Biomedical Computer Systems, Faculty of Computer Science and Materials Science (Institute of Computer Science), University of Silesia, Ul. Będzińska 39, 41-200 Sosnowiec, Poland 2 Chair and Department of Ophthalmology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland 3 Department of Basic Biomedical Science, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Sosnowiec, Poland 4 Multidisciplinary Department of Medical, Surgical and Dental Sciences, Università della Campania Luigi Vanvitelli, Napoli, Italy 5 Academy of Technological Sciences of Ukraine, National University of Kiev, Kiev, Ukraine 6 2VisareRIO, Instituto de Olhos Renato Ambrósio, Rio de Janeiro, RJ, Brazil 7 Rio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, RJ, Brazil 8 Brazilian Study Group of Articial Intelligence and Corneal Analysis-BRAIN, Rio de Janeiro, RJ, Brazil 9 Department of Ophthalmology/DECIGE, Federal University of the State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil 10 Department of Ophthalmology, Federal University of São Paulo, São Paulo, SP, Brazil Correspondence should be addressed to Robert Koprowski; [email protected] Received 31 January 2018; Accepted 31 January 2018; Published 20 May 2018 Copyright © 2018 Robert Koprowski et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This special edition concerns image processing in ophthal- mology. This issue is related to a variety of modern imaging methods. Precise discernment of a disease, its correct diag- nosing, eectual planning, and successful realization of treat- ment, especially surgical, in any branch of medicine, including ophthalmology, cannot be provided today without specic techniques of image processing and quantitative data. Each and every obtained quantitative result is the out- come of image analysis and processing algorithms imple- mented in a software. However, the software is not always perfect. Even today, the software does not provide fully auto- matic, reproducible, and quantitative results in the case of high interindividual variability. Therefore, the software in ophthalmology implementing corresponding algorithms must be tailored for specic applicationsanalysis of the ret- ina, cornea, and so on. This area of image processing has been addressed in six articles included in this special edition. Imaging the blood vessels, their accentuation, or even extraction is still the area of interest. It concerns the selection of image analysis and processing methods to extract blood vessels. It is a real art to nd a segmentation method whose results are independent of the image angle (rotation). Z. Yavuz and C. Köse proposed a method using four stages: preparation of a dataset for segmentation; Gabor, Frangi, and Gauss ltration and top-hat transform; and K-means and fuzzy c-means clustering and removal of falsely seg- mented isolated regions. The obtained results relate to the K-means clustering method95.94% and 95.71% of accu- racy for STARE and DRIVE databases. A similar issue was discussed in the article written by R. Ramli et al., who used a dierence of Gaussian pyramid with a saddle detector. This pyramid was tested on the Fundus Image Registration Data- set consisting of 134 retinal image pairs. The authorsresults showed that D-Saddle registered 43% of retinal image pairs with an average registration accuracy of 2.329 pixels. The method proposed by R. Ramli et al. provides much better results compared to the results known today. A new method of analysis and interesting results are also presented in the Hindawi Journal of Healthcare Engineering Volume 2018, Article ID 1545632, 2 pages https://doi.org/10.1155/2018/1545632

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Page 1: Editorial Image Processing in Ophthalmologydownloads.hindawi.com/journals/jhe/2018/1545632.pdf · Editorial Image Processing in Ophthalmology Robert Koprowski ,1 Anna Nowińska,2

EditorialImage Processing in Ophthalmology

Robert Koprowski ,1 Anna Nowińska,2 Sławomir Wilczynski,3 Michele Lanza ,4

Vasyl Molebny,5 and Renato Ambrosio Jr. 6,7,8,9,10

1Department of Biomedical Computer Systems, Faculty of Computer Science and Materials Science (Institute of Computer Science),University of Silesia, Ul. Będzińska 39, 41-200 Sosnowiec, Poland2Chair and Department of Ophthalmology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia,Katowice, Poland3Department of Basic Biomedical Science, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, MedicalUniversity of Silesia, Sosnowiec, Poland4Multidisciplinary Department of Medical, Surgical and Dental Sciences, Università della Campania Luigi Vanvitelli, Napoli, Italy5Academy of Technological Sciences of Ukraine, National University of Kiev, Kiev, Ukraine62VisareRIO, Instituto de Olhos Renato Ambrósio, Rio de Janeiro, RJ, Brazil7Rio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, RJ, Brazil8Brazilian Study Group of Artificial Intelligence and Corneal Analysis-BRAIN, Rio de Janeiro, RJ, Brazil9Department of Ophthalmology/DECIGE, Federal University of the State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil10Department of Ophthalmology, Federal University of São Paulo, São Paulo, SP, Brazil

Correspondence should be addressed to Robert Koprowski; [email protected]

Received 31 January 2018; Accepted 31 January 2018; Published 20 May 2018

Copyright © 2018 Robert Koprowski et al. This is an open access article distributed under the Creative Commons AttributionLicense, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work isproperly cited.

This special edition concerns image processing in ophthal-mology. This issue is related to a variety of modern imagingmethods. Precise discernment of a disease, its correct diag-nosing, effectual planning, and successful realization of treat-ment, especially surgical, in any branch of medicine,including ophthalmology, cannot be provided today withoutspecific techniques of image processing and quantitativedata. Each and every obtained quantitative result is the out-come of image analysis and processing algorithms imple-mented in a software. However, the software is not alwaysperfect. Even today, the software does not provide fully auto-matic, reproducible, and quantitative results in the case ofhigh interindividual variability. Therefore, the software inophthalmology implementing corresponding algorithmsmust be tailored for specific applications—analysis of the ret-ina, cornea, and so on. This area of image processing hasbeen addressed in six articles included in this special edition.

Imaging the blood vessels, their accentuation, or evenextraction is still the area of interest. It concerns the selection

of image analysis and processing methods to extract bloodvessels. It is a real art to find a segmentation method whoseresults are independent of the image angle (rotation). Z.Yavuz and C. Köse proposed a method using four stages:preparation of a dataset for segmentation; Gabor, Frangi,and Gauss filtration and top-hat transform; and K-meansand fuzzy c-means clustering and removal of falsely seg-mented isolated regions. The obtained results relate to theK-means clustering method—95.94% and 95.71% of accu-racy for STARE and DRIVE databases. A similar issue wasdiscussed in the article written by R. Ramli et al., who useda difference of Gaussian pyramid with a saddle detector. Thispyramid was tested on the Fundus Image Registration Data-set consisting of 134 retinal image pairs. The authors’ resultsshowed that D-Saddle registered 43% of retinal image pairswith an average registration accuracy of 2.329 pixels. Themethod proposed by R. Ramli et al. provides much betterresults compared to the results known today. A new methodof analysis and interesting results are also presented in the

HindawiJournal of Healthcare EngineeringVolume 2018, Article ID 1545632, 2 pageshttps://doi.org/10.1155/2018/1545632

Page 2: Editorial Image Processing in Ophthalmologydownloads.hindawi.com/journals/jhe/2018/1545632.pdf · Editorial Image Processing in Ophthalmology Robert Koprowski ,1 Anna Nowińska,2

work of A. Lyssek-Boroń et al. In this work, the authorsanalyse retinal OCT. By comparing the group with open-angle glaucoma and the group without glaucoma, theydemonstrated that the retinal nerve fibre layer thickness inthe temporalis quadrant decreases significantly 6 monthsafter surgery. Measurements of corneal thickness in theeyes with pseudoexfoliation syndrome are presented byK. Krysik et al. They showed that the mean CCT in theeyes with PEX syndrome measured with three instrumentswas thicker compared to that in the normal eyes. The resultsconcerned 128 eyes of patients with diagnosed PEX and 112normal eyes.

Two of the articles concern the cornea and pupil. One ofthe papers written by P. Kasprowski and K. Harezlak isdevoted to the vision diagnostics and treatment system forchildren with disabilities. This system enables to track eyeballmotility. The presented system is equipped with specializedsoftware. This system allows stimulation of children’s visionwith a dedicated stimulus and post hoc analyses of recordedsessions. It is therefore an extremely useful tool for both anophthalmologist and neurologist. The other article writtenby R. Koprowski and S. Wilczyński focuses on the dynamicsof the cornea. Monitoring of the cornea during intraocularpressure measurements provides additional parameters suchas amplitude of vibrations or their phase. This is discussed indetail in the mentioned article.

In summary, this special edition is mainly devoted to themethods based on the detection and segmentation of vesselsand arterioles of the retina; there are also articles discussingOCT, eye tracking, and a high-speed Scheimpflug camera.We hope that this special edition will bring new knowledgeand will be interesting and inspiring for the readers.

Robert KoprowskiAnna Nowińska

Sławomir WilczynskiMichele LanzaVasyl Molebny

Renato Ambrosio

2 Journal of Healthcare Engineering

Page 3: Editorial Image Processing in Ophthalmologydownloads.hindawi.com/journals/jhe/2018/1545632.pdf · Editorial Image Processing in Ophthalmology Robert Koprowski ,1 Anna Nowińska,2

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