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Early Onset of Schizophrenia Spectrum Disorder

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Early Onset of Schizophrenia Spectrum Disorder. Premorbid history. Language abnormalities. Social impairment. Attention problems. Schizophrenia Biologic Etiology. Neuropathology in structure, function, and neurotransmitters, especially in temporal and frontal regions. Genetic diathesis. - PowerPoint PPT Presentation

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  • Early Onset of Schizophrenia Spectrum DisorderPremorbid historyAttention problemsSocial impairmentLanguage abnormalities

  • Schizophrenia Biologic EtiologyNeuropathology in structure, function, and neurotransmitters, especially in temporal and frontal regionsLanguage impairmentNeurocognitive impairmentIntra uterine stressGenetic diathesis

  • Schizophrenia Psychosocial EtiologyCommunication devianceLife events and stress

  • Schizophrenia Differential DiagnosisBipolar DisorderADHDConduct DisorderPTSDPDD

  • Schizophrenia PrognosisPoor - early onset, neurologic abnormalities, negative symptomsGood - higher IQ, precipitant

  • Psychopharmacology for Children and AdolescentsStimulantsAntidepressantsMood stabilizers

  • Psychopharmacology for Children and Adolescents (Contd)NeurolepticsMinor tranquilizersAdrenergic agonists

  • Attention Deficit Disorder Decision TreeInattentionImpulsivitybupropionclonidinetricyclicSSRICombinationsMood StabilizersBusparBeta blockersMethylphenidateDextroamphetamine

  • StimulantsMethylphenidate (Ritalin)Dextroamphetamine (Dexedrine)AdderallMagnesium pemoline (Cylert)

  • Antidepressants for ADHDFluoxetine (Prozac)Bupropion (Wellbutrin)Venlafaxine (Effexor)Tricyclics

  • Other Treatments for ADHDAlpha-adrenergic stimulating agentsBeta-adrenergic blocking agents

  • Depression Decision TreeNoradrenergicSerotoninergicBupropion VenlafaxineRemeronStimulantsB-blockersSSRIBuSparValproateCarbamazepineLithium

  • Treatment of PsychosisAtypical neurolepticsRisperidoneOlanzapineQuetiapineMood stabilizersValproateLithiumCarbamazepine

  • Ideally, one would like to practice medicine without having to bother with actual patients.

  • Other Treatment Modalities for Neurodevelopmental DisordersSocial skills trainingStress managementCognitive-Behavioral Treatment (CBT)School AccommodationSpecialized neuropsychological approachesFamily structure and supportPsychotherapy

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