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E-Seminar Protocols

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your phone line while listening

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One-Minute NMR2007 demo tour

• University of Buffalo: Buffalo, NY; January 8• TriMR Regional Meeting: Research Triangle Pk, NC; Feb 15-16• Southwest Regional Demonstration, San Diego, CA; Mar 27 (anticip)• ENC: Daytona Beach, FL; April 22 – 26 (anticip)• Schedule a live demo in your area! Call Protasis for details.

6 March, 2007

Presented by Tim Peck

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One-Minute NMRWinter 2006-07

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Metabonomics Research DayUniversity of Buffalo Amherst

January 8, 2007

Natural Sciences Complex Center for Tomorrow

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Metabonomics Research DayUniversity of Buffalo Amherst

Morning SessionMetabonomics and Top-Down Systems Biology:From Personalized Healthcare to Molecular Epidemiology

Plenary Speaker:Professor Jeremy Nicholson

1H-NMR Metabonomics for Detecting Epithelial Ovarian Cancer

Dr. Kunle OdunsiDept of Gynecologic OncologyRPCI

Prof. Gail WillskyDept of BiochemistryUniv. Buffalo

Effects of Ligand and Ability to Lower Blood Glucose on Global Gene Expression in STZ-Diabetic Rats Treated with Oxovanadium Compounds

Prof. Frank SchroederCornell University and Harvard Medical School

The virtue of the impure: chemical biology revealed by direct NMR

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Metabonomics Research DayUniversity of Buffalo Amherst

Afternoon Roundtable

Session 1: Scientific Infrastructure for Metabonomics – Instrumentation, Software and Databases

Dinesh Sukumaran, Ph.D.Director, Magnetic Resonance CenterDepartment of Chemistry, U. Buffalo

Session 2: Synergy of NMR Spectroscopy and Mass Spectrometry in MetabonomicsProf. Thomas SzyperskiDept. of Chemistry and BiochemistryU. Buffalo

Session 3: Metabonomics – Related Research

Prof. George DeTittaDept. Structural BiologyU. Buffalo

Session 4: Metabonomics in an ‘ohmics’ world

Prof. Jeremy NicholsonDept. of Biological ChemistryImperial College

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TriMR Regional MeetingResearch Triangle Park

Feb. 15, 2007

• Hosted at GlaxoSmithKline

Vs.

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TriMR Regional MeetingResearch Triangle Park

Feb. 15, 2007

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One-Minute NMR:Integrated System Approach

6- or 12-TrayCapacityfor Vialsor Trays

Multi-SolventWash Station

SampleReturn

Accident-FreeSyringeand Needle

Web-basedSoftware

Well Plate or VialSample Format

CapNMR Probe5- or 10-µL

DiscoveryTower

On-BoardInstrument

Server

• Microliter precision• 0.1 mm xyz positioning

Well Plate orVial Tray

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Automation: Accident-Free Syringe and Needle

Carriage comes to restbefore needle is lowered

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Automation: Solvent Conditioner

Solvent BottlesUnder Positive Pressure

Solvent ConditionerVacuum Pump

Result: Dry, Degassed, ProtectedDeuterated Solvent

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IntegratedApproach

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MicroFlow NMR Literaturewww.microNMR.com

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Your MicroFlow NMR Product Sourcewww.protasis.com