DYNHOM symposium May 2017 : the homeopathic … · DYNHOM symposium May 2017 : the homeopathic remedy and its action, new scientific evidence. Table 2: HPLC-UV quantification of sempervirine

DYNHOM symposium May 2017 : the homeopathic remedy and its action, new scientif ic

evidence.

Ahomeopathicdilutionisnotjustasimpledilution:

Dilutingun-ionisedwaterinapharmaceuticalvialinsuccessivestepsforciblyandsystematicallyremovesmaterialdepositedontheglass;thisphenomenondoesnotoccurwithpolyethylenevials.(Schema1)

Homeopathicrawmaterialsdilutedandvigorouslyshaken(sucussion)ateachstepallowsfordetectionofadditionalmaterialderivedfromthehomeopathicstock.Thismaterialcanalsobefoundwhenusingpolyethylenevialsandismaterialclearlyderivedfromthestock.(Schema2)

Thismethodofdilutionincludingsuccessiveandsystematicshaking(providesadditionalenergy)betweeneachdilution+dynamisationallowspreservinguniquecompositematerial.(Table1)

Ahomeopathicdilution+dynamisationisspecific:

Usingtraditionalmethods,itispossibletodetecttherawmaterialsformingthestockupto6D(3CH);at4CH(10-8)onecanstilldetectsomepartsofthestockbutbeyondthatdilution,thisisnolongerpossible.(Table2)

Themostmodernmethods(NTA)allowfordetectionofthequantity,sizeanddistributionofparticles,whicharestockspecific,beyondthedilution4CH.(Schema3)

Usinglaserelectronicmicroscopy(SEM),onecanobservespecificanddistinctshapesofparticles(whichcanbedistinguishedonefromanother).Theirchemicalcompositions(EDX)arealsodistinct.(Schema4&5).

Thebehaviourofaqueoussolventismodifiedbythepresenceoftheseparticles.Thiscanbeobservedusingnuclearmagneticresonance.Itispossibletotellthedifferencebetweendiluted+dynamisedstocks,whereasitisimpossibletodiscernadifferencebetweenstockswhichareonlydiluted.(Schema6)

Onecandistinguishoneremedyfromanotherthroughelectro-photonicanalysisofadrop(classichydro-alcoholdynamisedsolutions)orofanimpregnatedpill,evenatthehighestdilutions+dynamisations.(PicturesAqua/Cuprum/Gelsemium).


evidence.

DYNHOMCONCLUSIONS:Homeopathicremediesareuniqueandcanbedistinguishedfromoneanotheronthebasisoftheirphysico-chemicalandparticulatecharacteristicsinalloftheirdilutions+dynamisations,butalso,thankstotheirsignatureinthesolvent.

Thesignatureofimpregnatedpillsisstableanddurable.

GENERALCONCLUSIONSFORHOMEOPATHY:• Otherresearchteamshavepublishedmodificationsofobservedgeneexpressionusingtechniquestraditionallyemployedinuniversityand

hospitalcentres(DNAchipmicroarraysandPCR)andeachremedy,evenathighdilutions+dynamisations,directlyregulatesalimitedandspecificseriesofgenes.Themalfunctioningofthesegenesisexpressedbyspecificsymptomsobservedinhumanbeings.(Schema7)

• Thespecificsignatureofaremedyisdirectly(throughperlingualabsorption)transmittedtothebloodandtransportedtospecificreceptivegeneswhichare,thus,regulatedandwhich,inturn,causesthesymptomstodisappear.

• Thismodeofactioncanbefullyexplainedbytheprinciplesofquantumphysics.

• Basicresearch,aswellasclinicalobservations,areanintegralpartofevidencebasedmedicine(EBM) .

Water Copper Gelsemium


evidence.

References1. VanWassenhovenM.,GoyensM,CapieauxE,DevosP(2017).NanoparticleCharacterizationofTraditionalHomeopathically-ManufacturedGelsemiumSempervirens

MedicinesandControls.Homeopathy(2017)Inpublication.2. VanWassenhovenM.,GoyensM,CapieauxE,DevosP(2017).NanoparticleCharacterizationofTraditionalHomeopathically-ManufacturedCopper(Cuprum

metallicum)MedicinesandControls.Homeopathy(2017)Inpublication.3. VanWassenhovenM.,GoyensM,HenryM,CapieauxE,DevosP(2017).NuclearMagneticResonanceCharacterizationofTraditionalHomeopathically-Manufactured

Copper(CuprumMetallicum)andaplant(GelsemiumSempervirens)MedicinesandControls.Homeopathy(2017)Inpublication.4. HenryM,VanWassenhovenM.,GoyensM,CapieauxE,DevosP(2017).Electro-photonicCharacterizationofTraditionalHomeopathically-Manufacturedcopper

(CuprumMetallicum)andaplant(GelsemiumSempervirens)SolutionsandImpregnatedpillsandControls.(2017)Inpublication.5. CapieauxE(2014).Exemplesdevérificationsdeshautesdynamisationsparlatechnique“Microarrays”(invitroetinvivo).ColloqueDynhom2014.6. CapieauxE(2016).BiologicalEvidenceforanEffectofHighHomeopathicPotenciesusingBiomolecularTools.VIICongresoNationalHomeopatia.Donostia2016.


evidence.


evidence.

Schema1:Nanotrackinganalyses:Numberofparticlescountedforeachframe.


evidence.

0

0,5

1

1,5

2

2,5

3

Aquapura30KPET Aquapura30CGlass

LimitforvalidcounengofpareclesforNTA


evidence.

Schema2:Nanotrackinganalyses:Numberofparticlescountedforeachframe.


evidence.

Table1:Atompercentagesdetected*atomicmass*quantityofcollectedmaterialinµg.

0

0,5

1

1,5

2

2,5

3

Aquapura30CGlass Gelsemium30CGlass Aquapura30KPET Cuprum30KPET


evidence.

A q u a 3 0 C

C u p r 4 C

C u p r 3 0 C

C u p r 2 0 0 K

C u p r 1 0

- 6 0

C u p r 3 0 C P E T

A r g 3 0 C

A r g 2 0 0 K

A r g 1 0

- 6 0

S i l 3 0 C

S i l 2 0 0 K

S i l 1 0

- 6 0

K a l i - m 3 0 C

G e l s 3 0 C

C a r b o n 4 0 0 , 8 2 4 0 9 9 , 1 2 1 9 8 , 1 2 5 0 8 , 2 9 9 3 , 9 6 3 4 0 , 0 2 4 3 6 4 , 4 1 0 9 4 , 5 2 4 5 8 8 , 8 2 3 2 7 , 0 4 2 6 1 7 , 9 2 3 4 8 1 , 5 6 9 6 9 4 , 0 8 1 5 6 0 3 , 8 4

O x y g e n 1 6 2 3 , 0 4 1 0 8 5 1 , 8 4 8 1 1 , 8 4 2 0 4 7 , 2 2 2 6 3 , 2 1 2 1 1 , 0 4 6 9 8 2 , 4 5 9 3 3 , 7 6 1 6 9 6 3 , 2 9 7 2 4 , 8 5 7 8 8 , 1 6 1 5 0 4 4 , 9 6 8 6 1 4 , 2 4 2 4 1 4 5 , 9 2

N a t r i u m 8 5 0 , 5 4 6 8 , 3 1 4 2 4 , 5 8 1 2 1 5 , 5 5 1 0 2 3 , 2 7 9 0 1 , 4 8 5 3 7 7 6 , 6 3 5 8 8 , 6 9 6 6 8 3 , 8 4 5 5 6 , 7 6 3 8 4 9 , 2 8 4 2 3 4 , 5 3 2 7 9 9 , 5 6 1 4 5 5 6 , 2 4

S i l i c i u m 4 6 3 , 6 8 2 7 9 , 7 2 1 8 7 , 0 4 3 9 4 , 8 4 8 8 , 0 4 5 0 , 8 2 3 8 9 , 2 1 2 6 6 , 1 6 3 0 8 5 , 6 1 7 6 0 , 6 4 8 0 8 , 6 4 1 0 5 1 7 , 6 4 3 4 3 6 , 7 2 1 4 3 1 , 3 6

C a l c i u m 2 3 9 , 2 0 1 6 1 , 2 2 5 3 2 5 4 , 4 2 7 2 4 0 3 6 1 , 2 3 3 9 2 3 2 7 3 , 6 3 0 4 1 1 3 2 , 4 1 8 9 7 , 2 0

M a g n e s i u m 5 9 , 2 9 2 0 1 7 , 9 8 2 4 9 , 2 0 7 5 7 9 , 4 6 1 3 9 , 7 3 0 5 8 2 , 6 2 4 0 1 , 4 3 6 4 0 3 , 3 8 2 0 9 , 9 5 2 1 8 2 , 7 3 6 7 8 9 , 5 0 7 3 3 0 , 4 8 0

S u l f u r 1 4 , 0 8 0 1 4 , 0 8 1 3 , 6 2 5 , 9 2 1 7 , 2 8 1 4 7 , 2 1 0 9 , 7 6 2 3 0 , 4 9 9 , 8 4 6 4 0 1 0 1 7 , 2 8 1 3 2 4 , 8

A l u m i n i u m 1 3 , 5 0 1 0 , 2 6 2 2 , 9 5 3 0 , 7 8 1 7 , 0 1 6 4 , 8 3 4 , 0 2 2 2 1 , 4 1 4 5 , 8 5 6 , 1 6 6 6 6 , 9 1 4 6 , 8 8 8 2 6 , 2

K a l i u m 6 5 , 5 2 0 4 2 , 9 7 0 , 2 6 0 , 8 4 3 3 , 3 4 5 1 4 0 , 4 1 4 7 , 4 2 7 4 8 , 8 1 0 6 2 , 3 6 1 2 4 , 8 6 3 7 , 2 6 3 4 4 , 7 6 7 7 2 , 2

M o l y b d e n u m 0 0 0 0 0 0 0 0 0 0 0 2 5 5 , 3 6 0 0

C h l o r i n e 2 0 , 5 9 0 2 4 , 1 4 4 7 , 9 2 5 2 1 , 3 8 0 , 4 0 7 5 6 3 , 9 9 4 , 4 3 7 3 1 , 3 3 8 7 , 6 6 5 3 , 9 6 1 2 8 , 1 5 5 7 8 , 4 5 5 5 3 6 , 7 6

B a r i u m 0 0 0 0 0 0 0 0 0 0 0 7 5 4 , 8 7 0 0


evidence.

Table2:HPLC-UVquantificationofsempervirineandgelsemine(alkaloidsmarkers)inGelsemium.

Sempervirine Gelsemine (Mean ± standard deviation) (Mean ± standard deviation) Mother Tincture (dilution 50x) 577.1 µg/ml ± 1.1 354.0 µg/ml ± 1.5 Mother Tincture (dilution 20x) 577.5 µg/ml ± 3.8 360.2 µg/ml ± 0.3 1D 165.5 µg/ml ± 1.7 116.1 µg/ml ± 1.7 10-1 179.0 µg/ml ± 0.8 111.6 µg/ml ± 1.7 2D 16.1 µg/ml ± 1.8 15.5 µg/ml ± 1.5 10-2 16.0 µg/ml ± 2.5 17.9 µg/ml ± 5.1 3D 1.51 µg/ml ± 1.8 1.44 µg/ml ± 2.2 10-3 1.56 µg/ml ± 2.7 1.44 µg/ml ± 3.3 4D 0.117 µg/ml ± 8.3 0.115 µg/ml ± 2.8 10-4 0.117 µg/ml ± 5 0.112 µg/ml ± 2.7 5D 0.00722 µg/ml ± 11.1 0.01076 µg/ml ± 11.2 10-5 0.00749 µg/ml ± 2.4 0.01074 µg/ml ± 0.7 6D Non quantifiable Non quantifiable 10-6 Non quantifiable Non quantifiable


evidence.

Schemas3:Particlessizesinnanometersandparticlessizesdistributions.


evidence.


evidence.

Schema4:Identifiedchemistryindilutions/potentizations(atom%*atomicmass*µgquantity)forthe5mostconcentratedatomsinthedifferentpreparations.

CONaSiCaThereisadifferenceinchemistrybetweenthedifferentsamples.TheproportionofCarbon,Oxygen,Sodiumarealwayshigh,SiliciumandCalciumarealsogooddiscriminantfactors.Cuprum4Cisalmostpuresugar(C11H22O11)andrealvaluesareabout9000timeshigherthanpresentedhere.Atthisscale,the

-20

4980

9980

14980

19980

24980

29980

Aqua30C

Cupr4C

Cupr30C

Cupr200K

Cupr10-60

Cupr30CPET

Arg30C

Arg200K

Arg10-60

Sil30C

Sil200K

Sil10-60

Kali-m30C


evidence.

differentdilutions/potentizationsofcopperarenoteasilydiscriminatedfromeachotherbutitiseasytodiscriminatefromothermetalsorsaltorplant.Forsilverandsilicathedifferencesbetweendilutions/potentizationsareclearlyexpressed.

Schema5:Identifiedchemistryindilutions/potentizations(atom%*atomicmass*µgquantity)for6lowerconcentratedatomsinthedifferentpreparations.

-20

180

380

580

780

980

1180

1380

1580

Aqua30C

Cupr4C

Cupr30C

Cupr200K

Cupr10-60

Cupr30CPET

Arg30C

Arg200K

Arg10-60

Sil30C

Sil200K

Sil10-60

Kali-m30C


evidence.

MgSAlKMoClAlsoforlowerconcentratedatoms,thereisadifferenceinchemistrybetweenthedifferentsamplesandaregooddiscriminantfactors.Atthisscale,Cuprumdilutions/potentizationschemistryisnotaseasytodiscriminatebetweeneachotherfortheseatomsbuteasytodiscriminatefromotherpreparations.


evidence.

Schema6:ComparisonofmeanrelaxationtimesofGelsemium&Cuprum.


evidence.

Schema7:ExampleofGelsemium2-3-4-5-9-30CH&micro-arrays45.033Humangenesexpressedononemicroplate.

Ref.Marzottoetal.ExtremesensitivityofgeneexpressioninhumanSH-SY5Yneurocytestoultra-lowdosesofGelsemiumsempervirens.BMCComplementaryandAlternativeMedicine2014,14:104.

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DYNHOM symposium May 2017 : the homeopathic … · DYNHOM symposium May 2017 : the homeopathic remedy and its action, new scientific evidence. Table 2: HPLC-UV quantification of sempervirine