2
Creates a moist wound environment, facilitates good wound bed preparation • Cleanses the wound, reduces unpleasant odor • Debrides by autolysis, aids eschar removal • Stimulates wound healing • Anti-inflammatory Package Reorder No. Description Quantity Comparable Products HCPCS 3071 Tulle Dynarex L-Mesitran Tulle Dressings 4˝ × 4˝ 10/10/Cs Dukal Activon ® Manuka Honey Tulle A4649 3073 Border Dynarex L-Mesitran Border Dressings 4˝ × 4˝ 10/10/Cs Derma Sciences MediHoney ® Hydrogel Adhesive A6245 3075 Hydro Dynarex L-Mesitran Hydro-Active Dressings 4˝ × 4˝ 10/10/Cs Derma Sciences MediHoney ® Hydrogel Non-Adhesive A6242 3077 Soft Dynarex L-Mesitran Soft Wound Gel 0.5 oz. 24/1/Cs Medline TheraHoney ® Gel A6250 3078 Soft Dynarex L-Mesitran Soft Wound Gel 1.75 oz. 24/1/Cs Medline TheraHoney ® Gel A6250 is your one-stop medical supply company since 1967 10 Glenshaw Street • Orangeburg, NY 10962 • www.dynarex.com For more information contact your local Dynarex ® distributor sales representative. Or call 888-396-2739 to find your nearest distributor. © 2017 Dynarex Corporation WE CARE LIKE FAMILY Find us on: 3073 Border 3075 Hydro 3078 Soft 3077 Soft 3071 Tulle See website for our Hydrocolloid Dressings (Reorder Nos. 3014-3020) Activon ® is a registered trademark of Brightwake Ltd. MEDIHONEY ® is a trademark of Comvita New Zealand Ltd. and is used with permission by Derma Sciences. TheraHoney ® is a registered trademark of Medline Industries, Inc. See our website for other Marketing & Reference Materials and Related Links! Dynarex L-Mesitran Honey

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Creates a moistwound environment,facilitates goodwound bedpreparation• Cleanses the wound,

reduces unpleasant odor• Debrides by autolysis,

aids eschar removal• Stimulates wound healing• Anti-infl ammatory

Package ReorderNo. Description Quantity Comparable

Products HCPCS

3071Tulle

Dynarex L-MesitranTulle Dressings

4˝ × 4˝10/10/Cs

Dukal Activon® Manuka Honey

TulleA4649

3073Border

Dynarex L-MesitranBorder Dressings

4˝ × 4˝10/10/Cs

Derma SciencesMediHoney®

HydrogelAdhesive

A6245

3075Hydro

Dynarex L-MesitranHydro-Active

Dressings4˝ × 4˝

10/10/Cs

Derma SciencesMediHoney®

HydrogelNon-Adhesive

A6242

3077Soft

Dynarex L-MesitranSoft Wound Gel

0.5 oz.24/1/Cs

MedlineTheraHoney®

GelA6250

3078Soft

Dynarex L-MesitranSoft Wound Gel

1.75 oz.24/1/Cs

MedlineTheraHoney®

GelA6250

Creates a moistwound environment,facilitates goodwound bedpreparation• Cleanses the wound,

reduces unpleasant odor• Debrides by autolysis,

aids eschar removal• Stimulates wound healing• Anti-infl ammatory

Package ReorderNo. Description Quantity Comparable

Products HCPCS

3071Tulle

Dynarex L-MesitranTulle Dressings

4˝ × 4˝10/10/Cs

Dukal Activon®

Manuka Honey Tulle

A4649

3073Border

Dynarex L-MesitranBorder Dressings

4˝ × 4˝10/10/Cs

Derma SciencesMediHoney®

HydrogelAdhesive

A6245

3075Hydro

Dynarex L-MesitranHydro-Active

Dressings4˝ × 4˝

10/10/Cs

Derma SciencesMediHoney®

HydrogelNon-Adhesive

A6242

3077Soft

Dynarex L-MesitranSoft Wound Gel

0.5 oz.24/1/Cs

MedlineTheraHoney®

GelA6250

3078Soft

Dynarex L-MesitranSoft Wound Gel

1.75 oz.24/1/Cs

MedlineTheraHoney®

GelA6250

is your one-stop medical supply company since 1967

10 Glenshaw Street • Orangeburg, NY 10962 • www.dynarex.com

For more information contact your local Dynarex® distributor sales representative.Or call 888-396-2739 to find your nearest distributor.

© 2017 Dynarex Corporation

WE CARE LIKE FAMILY™

Find us on:

3073 Border 3075 Hydro

3078 Soft

3077 Soft

3071 Tulle

Anti-infl ammatory

See website for our HydrocolloidDressings (Reorder Nos. 3014-3020)

Activon® is a registered trademark of Brightwake Ltd.MEDIHONEY® is a trademark of Comvita New Zealand Ltd. and is used with permission by Derma Sciences.

TheraHoney® is a registered trademark of Medline Industries, Inc.

See our website for other Marketing &Reference Materials and Related Links!

Dynarex L-Mesitran Honey

WE CARE LIKE FAMILY™

is your one-stop medical supply company since 1967Find us on:

rev. 0117

10 Glenshaw Street • Orangeburg, NY 10962 • www.dynarex.com

For more information contact your local Dynarex® distributor sales representative.Or call 888-396-2739 to find your nearest distributor.

© 2017 Dynarex Corporation

Dynarex L-Mesitran Tulle Dressings

4˝ × 4˝

Contain 40% honey (Soft ± 4 gram) pH ± 4.0. A synthetic gauze, conformable, easy to apply, can be used with L-Mesitran Soft. Wound types: Acute and chronic wounds, infected wounds with

(lots of) exudate.3071 HCPCS: A4649

Dynarex L-Mesitran Hydro-Active Dressings

4˝ × 4˝

Contain 30% Medical grade honey. They're a bacterial barrier, create a moist wound healing environment, and absorb low to high levels of exudate. Wound types: Acute and chronic wounds with light to high exudate. No contraindications known to date � ve days in-situ (depending on

amount of wound exudate.)3075 HCPCS: A6242

Dynarex L-Mesitran Border Dressings

4˝ × 4˝

Contain 30% Medical grade honey. They're a bacterial barrier, create a moist wound healing environment, and absorb low to high levels of exudate. Wound types: Acute and chronic wounds with light to high exudate. No contraindications known to date � ve days in-situ (depending on

amount of wound exudate.)3073 HCPCS: A6245

Dynarex L-MesitranSoft Wound Gel0.5 oz. & 1.75 oz.

Wound types/indications: Pressure ulcers, � rst & second degree burns, venous and arterial ulcers, diabetic (foot) ulcers, fungating wounds, donor sites, surgical wounds. Contraindications: None, although individuals with a known sensitivity to components should

be careful.3077 & 3078 HCPCS: A6250

Dynarex L-Mesitran

L-Mesitran Tulle

L-Mesitran Tulle is a non-adhering polyethylene dress-

ing, impregnated with L-Mesitran Soft gel that con-

tains 40% medical grade honey, hypo-allergenic lano-

lin, propylene glycol, PEG 4000, and vitamins C & E.

drawn from the surrounding tissues through osmosis.

By doing so, a moist wound healing environment is gnilaeh dnuow eht setalumits tnemnorivne sihT .detaerc

process.

L-Mesitran Tulle is an easy to use presentation as a sin-

gle use dressing and aims to provide patient comfort

and effective use of the gel. The Tulle dressing can stay

on the wound for several days and dressing changes

depend on the amount of wound exudates. The Tulle

will not adhere to the wound.

Indications

- Acute wounds such as cuts, abrasions and donor sites

burns (1st & 2nd degree)

- Chronic wounds e.g. pressure ulcers, venous and

arterial- Diabetic (foot) ulcers

- Fungating wounds (to help deodorise and/or debride)

- Colonised acute and (post-operative) surgical wounds

L-Mesitran Tulle provides a moist wound healing en-

vironment. This environment aids cleansing of the

wound and optimizes wound healing.

The gel does not adhere to the wound (it also prevents

the secondary dressing adhering to the wound). L-Me-

and reduces pain.

Case: Infected diabetic pressure ulcer

A female patient (65yrs) had a pressure sore (stage

II) on her right heel. The blister opened and got in-

fected, despite oral antibiotics. Due to the operation

the patient was weak, hardly had any appetite and was

depressed. She was also diabetic (Type 2) and her glu-

cose was deregulated after surgery.

MethodsAt the start of the honey treatment the wound was pro-

ducing high exudates. These exudates removed the

was changed 1x daily and covered with a foam dress-

only 3-4x per week. The dressing was applied directly

on the wound, after it was cleansed with tap water.

Results

and after approximately four weeks a clean and granu-

epithelised during the next three weeks and after sev-

en weeks the wound was fully healed (fig. 3). The

patient experienced no pain sensation during wear

time or at dressing changes. No maceration was ob-

served and the dressing created a moist wound envi-

ronment.

Product InformationTulle

1. First review

2. After 4 weeks

3. After 7 weeks

1011

604

0

50

100

150

200

250

300

350

Re-e

pith

eliali

zatio

n (μ

m)

SSD LM Soft

Application of L-Mesitran Soft resulted in significantly

more re-epithelialization in burns compared to silver

sulphadiazine.

(stage in-

operation was glu-

oduct Informationoduct Information

1011

601

1. First review

2. 29 days after hospital discharge

3. 60 days after hospital discharge

0

5

10

15

20

Absorption Moisture Vapour Transmission Rate (MVTR)Allevyn

g/m

2 (2

4hrs

) X

1.00

0

Total fluid handling(4 REPS 40ºC, 55% RH, 24hrs)

Fluid handling capacity of L-Mesitran Hydro, Border and Active Large

GranuflexL-Mesitran

L-Mesitran Hydro, BorderThe Hydro is a honey containing dressing for use on acute and chronic wounds. L-Mesitran Border isidentical, but with an adhesive border.

Hydro and Border are sterile, semi-permeable wound dressings containing 30% honey, an acrylic polymer gel and water with a polyurethane film backing, with and without an adhesive border.The honey-hydrogel pad donates moisture tore-hydrate dry tissue, and is also able to absorb low to high levels of exudate to help maintain a moist environment conducive to healing. The film backing provides the dressing with bacterial barrier properties. The adhesive border from the Border allows thedressing to be fixed securely. This is useful when patients need to shower or bathe with the dressingin place.

IndicationsBoth Hydro and Border are indicated for chronic wounds, such as:- pressure ulcers- superficial and partial thickness burns- venous, arterial and diabetic ulcers- fungating wounds.

They are also indicated for acute wounds such as:- donor sites- surgical wounds- cuts and abrasions

EfficacyHydro and Border quickly neutralize wound odors. The products provide a moist wound healing environment. This environment aids cleansing of the wound and optimizes wound healing.

The gel does not adhere to the wound. L-Mesitran hasno influence on blood glucose levels. The productshave a cooling effect, which is helpful with e.g. burns.

Case: BurnAn adult male (42 years), with an accidental burn sustained to the right upper extremity, including hand, after falling into a fire drum with hot coals.

MethodsTangential excision or skin grafting was not indicated and the wounds were initially dressed at the hospital with silver impregnated dressings before intentional conversion to L-Mesitran Hydro after hospital discharge. Before and after burn dressing treatment with the honey based dressings, and clinical outcome in this patient, are reflected in figures 1-3.

ResultsSatisfactory wound healing and burn epithelialization was complete in sixty days, and the rehabilitation at home was successful and facilitated by strict sepsis surveillance and nutritional support. Both a positive subjective and objective end result or measured-out-come followed the use of the honey based dressings of choice.

Three month follow-up after the burn showed minimal depigmentation, hyperpigmentation and hyperplastic scar tissue resulting in no elbow, wrist or finger contractures.

DiscussionBurn surface wound healing was affected bysecondary intention and the use of topical honey-based moist dressings, active movements of both extremity joints and hand to avoid contracture

Product InformationHydro & Border

dressing to be fixed securely. This is useful when patients need to shower or bathe with the dressingin place.

Satisfactory wound healing and burn epithelialization onment is gnilaehd

esentation as a sin-

patient comfort

essing can stay

essing changes

The T

and donor

e ulcers, venous and

and/or debride

surgical wounds

wound healing

cleansing of

wound and optimizes wound healing.

wound (it also pr

the wound).

MethodsAt the start of the honey treatment the wound was

ducing high exudates. These exudates removed

changed 1x daily and covered with a foam d

esulted in significantly

ed to silver

was pro-

emoved the

dress-

comfort stay

changes Tulle Tulle T

donor

e ulcers, venous and

debridewounds

healingof

rwound).

was changed 1x daily and covered with

Infected? No

Yes (*)

Is thewoundwet, moistor dry?

Is thewoundwet, moistor dry?

The wound is YELLOW

hydro-active dressings / provide and mantain moist

wound healing environment / supports optimal healing

Wet

Moist

Dryo Soft

o Soft

o Soft

o Tulle / Softo Hydro / Border

o Tulle / Softo Hydro / Border

o Hydro / Border

o Net

SUPERFICIALWOUNDS

DEEPWOUNDS

CHRONIC AND ACUTE WOUNDSClean the wound first (e.g. saline)

Clean the wound first (e.g. saline)

Infected? No

Yes (*)

Wet

Moist

Dry

o Soft / Tulle

o Tulle o Soft

o Tulleo Soft

o Softo Net

o Soft

o Soft

o Soft

o Soft

o Softo Net

The wound is BLACKo provides and maintains a

moist wound environment

o supports debridement

o provides and maintains a

moist wound environment

o supports optimal healing

and debridement

- closed wounds after suturing

- open wounds after suturing

o Hydro / Border POST-OPERATIVE WOUNDS

© Theo Manufacturing 2016 www.l-mesitran.com/us (*) In the event wounds are infected, seek appropriate advice from a physician

when applying L-Mesitran products.

The wound is REDo protective layer

o provides and maintains

a moist environment

o stimulate epithelisation

Wet

Moist

Dry

o Tulle / Soft

o Tulle / Soft o Hydro / Border

o Tulle / Softo Hydro / Border

o Softo Net

o Soft

o Soft

o Soft

o Soft

o Tulle / Soft

Clean the wound first (e.g. saline)

Wound Care Protocol usingL-Mesitran™ honey dressings

An adult male (42 years), with an accidental burn sustained to the right upper extremity, including hand, after falling into a fire drum with hot coals.

Tangential excision or skin grafting was not indicated and the wounds were initially dressed at the hospital with silver impregnated dressings before intentional conversion to L-Mesitran Hydro after hospital discharge. Before and after burn dressing treatment with the honey based dressings, and clinical outcome in this patient, are reflected in figures 1-3.

Satisfactory wound healing and burn epithelialization

Hydro & Border

Satisfactory wound healing and burn epithelialization

An adult male (42 years), with an accidental burn sustained to the right upper extremity, including hand, after falling into a fire drum with hot coals.

Tangential excision or skin grafting was not indicated and the wounds were initially dressed at the hospital with silver impregnated dressings before intentional conversion to L-Mesitran Hydro after hospital discharge. Before and after burn dressing treatment with the honey based dressings, and clinical outcome

Satisfactory wound healing and burn epithelialization

L-Mesitran SoftL-Mesitran Soft is a gel that contains: 40% medical grade honey, hypo-allergenic lanolin, propylene gly-col, PEG 4000, and vitamins C & E.

drawn from the surrounding tissues through osmosis. By doing so, a moist wound healing environment is created. This environment stimulates the wound heal-ing process.

L-Mesitran Soft is a primary wound dressing that can be covered with most commonly used secondary dressings. The properties of the gel also help prevent the secondary dressing adhering to the wound bed.

Indications- Chronic wounds.- Pressure ulcers (Stage I-IV).- Venous stasis ulcers.- Fungating wounds (to help deodorise and/or debride).

- Colonised acute wounds.- Surgical wounds, post-operative wounds.

L-Mesitran Soft provides a moist wound healing en-vironment. This environment aids cleansing of the wound and optimizes wound healing. The gel does not adhere to the wound (it also prevents the secondary dressing adhering to the wound). L-Me-and reduces pain.

Case: Leg ulcerA woman (57) with a general bad health condition and diabetes had an ulcer on her leg after a vein was re-iodine treatment for a week in the IC-unit.

Methods

Soft was applied in a thin layer. This was done by the home care nurse under supervision of the GP. ResultsIn the course of six weeks roughly 150g of L-Mesitran Soft was used and the wound healed. No adverse ef-shows there is little to no scarring. The necrotic and

-mately four weeks a clean and granulating wound bed the next three weeks and after seven weeks the wound pain during wear time or at dressing changes. No mac-

eration was observed and the dressing created a moist wound environment.

DiscussionThe debridement of the wounds was fast, which is one of the key features of honey based products. This eval-uation shows that this product can effectively combat

.noitasilehtipe dna noitalunarg etalumits dna snoitcefniThe wound healed completely without adverse effects and virtually no scarring.

Product InformationSoft

3. After 7 weeks

2. After 4 weeks

1. First review

1011

603

0

50

100

150

200

250

300

350

Re-e

pith

eliali

zatio

n (μ

m)

SSD LM SoftApplication of L-Mesitran Soft resulted in significantly more re-epithelialization in burns compared to silver sulphadiazine.

Case: Leg ulcer

drawn from the surrounding tissues through osmosis. By doing so, a moist wound healing environment is created. This environment stimulates the wound heal-ing process.

L-Mesitran Soft is a primary wound dressing that can be covered with most commonly used secondary dressings. The properties of the gel also help prevent the secondary dressing adhering to the wound bed.

Indications- Chronic wounds.- Pressure ulcers (Stage I-IV).- Venous stasis ulcers.Venous stasis ulcers.V

- Fungating wounds (to help deodorise and/or debride).- Colonised acute wounds.- Surgical wounds, post-operative wounds.

L-Mesitran Soft provides a moist wound healing en-vironment. This environment aids cleansing of the wound and optimizes wound healing. The gel does not adhere to the wound (it also prevents the secondary dressing adhering to the wound). L-Me-and reduces pain.

iodine treatment for a week in the IC-unit. Methods

Soft was applied in a thin layer.r.r Thishome care nurse under supervision of the GResultsIn the course of six weeks roughlySoft was used and the wound healed.

shows there is little to no scarring.mately four weeks a clean and granulatingthe next three weeks and after sevenpain during wear time or at dressingeration was observed and the dressingwound environment.

DiscussionThe debridement of the wounds was fast,of the key features of honey based products.uation shows that this product can effectivelyffectivelyf

nanoitalunargetalumitsdnasnoitcefniThe wound healed completely withoutand virtually no scarring.

3. After 7 weeks

2. After 4 weeks

1. First review

0

50

100

150

200

250

300

350

Re-e

pith

eliali

zatio

n (μ

m)

SSD LM SoftftfApplication of L-Mesitran Soft resulted in significantly more re-epithelialization in burns compared to silver sulphadiazine.

1. First review

2. 29 days after hospital

3. 60 days after hospital

dressing to be fixed securely. This is useful when patients need to shower or bathe with the dressing

Satisfactory wound healing and burn epithelialization was complete in sixty days, and the rehabilitation at home was successful and facilitated by strict sepsis surveillance and nutritional support. Both a positive subjective and objective end result or measured-outcome followed the use of the honey based dressings

Three month follow-up after the burn showed minimal depigmentation, hyperpigmentation and hyperplastic scar tissue resulting in no elbow, wrist or finger contractures.

Burn surface wound healing was affected bysecondary intention and the use of topical honey-based moist dressings, active movements of both extremity joints and hand to avoid contracture

provide and mantain moist

ent / supports optimal healing

o Soft

o Soft

o Soft

Tulle / Softo Hydro / Border

Tulle / Soft Hydro / Border

Hydro / Border

Net

SUPERFICIALWOUNDS

DEEPWOUNDS

o Soft / Tulle

o Tulleo Soft

o Tulleo Soft

o Softo Net

o Soft

o Soft

o Soft

o Soft

o Softo Net

o Hydro / Border

d, seek appropriate advice from a physician

o Tulle / Soft

o Tulle / Softo Hydro / Border

o Tulle / Softo Hydro / Border

o Softo Net

o Soft

o Soft

o Soft

o Soft

o Tulle / Soft

Wound Care Protocol using honey dressingsWound Care Protocol using honey dressingsWound Care Protocol using

1. First

2. 29 days after hospital

3. 60 days after hospital

home was successful and facilitated by strict sepsis surveillance and nutritional support. Both a positive subjective and objective end result or measured-outcome followed the use of the honey based dressings

Three month follow-up after the burn showed minimal depigmentation, hyperpigmentation and hyperplastic scar tissue resulting in no elbow, wrist or finger contractures.

Burn surface wound healing was affected bysecondary intention and the use of topical honey-based moist dressings, active movements of both extremity joints and hand to avoid contracture

Satisfactory wound healing and burn epithelialization was complete in sixty days, and the rehabilitation at home was successful and facilitated by strict sepsis

eview

2. 29 days after hospital

3. 60 days after hospital

Satisfactory wound healing and burn epithelialization was complete in sixty days, and the rehabilitation at home was successful and facilitated by strict sepsis surveillance and nutritional support. Both a positive subjective and objective end result or measured-outcome followed the use of the honey based dressings

Three month follow-up after the burn showed minimal depigmentation, hyperpigmentation and hyperplastic scar tissue resulting in no elbow, wrist or

Burn surface wound healing was affected bysecondary intention and the use of topical honey-based moist dressings, active movements of both extremity joints and hand to avoid contracture

Satisfactory wound healing and burn epithelialization was complete in sixty days, and the rehabilitation at home was successful and facilitated by strict sepsis surveillance and nutritional support. Both a positive

2. 29 days after hospital

3. 60 days after hospital

surveillance and nutritional support. Both a positive subjective and objective end result or measured-outcome followed the use of the honey based dressings

Three month follow-up after the burn showed minimal depigmentation, hyperpigmentation and hyperplastic scar tissue resulting in no elbow, wrist or

Burn surface wound healing was affected bysecondary intention and the use of topical honey-based moist dressings, active movements of both extremity joints and hand to avoid contracture

1

Clinical Data | Tabular summary May 2016

Case StudiesPublished Data for L-MesitranThis tabular summary is a quick guide to published data on L-Mesitran products.The list has been updated for all The most recent publications are listed �rst.

known published data on or before May 5, 2016.

In-vivo clinical studies (human)

Year Author Study type Wound type# patients

Summary

2015 HariKrishna R Non-randomised controlled case studies

carbuncle wounds, burns

4 Four patients with chronic wounds were treated with hon-ey based products. Wounds became clean and healing was noted. Therefore, this is a modality which we can use to get good wound closure. In these cases L-Mesitran Soft was used as it is more gentle and there was no stinging sensation.

2015 Aparício Case report Gliosarcoma, tumors

1 L-Mesitran Soft contributes to less malodor with malig-nant wounds. Patients diagnosed with gliosarcoma has a life expectancy of approximately 12 months. It is im-portant to control the symptoms caused by malignant wounds. Particulary to preserve as much quality of life as possible for the patient. 2015 Rodrigues

Almeida ACCase report Burns 1 L-Mesitran Tulle speeds up the healing process in the management of burns. The product induces better hy-dration and greater elasticity of the skin. After surgical debridement, application of mesh-shaped autografts onto the burned area (the upper leg and hip) and treat-ment with L-Mesitran Soft, the wound healed within 11 days.

2013 Boggust A Prospective Burns(pediatric)

11 Eleven children (6 girls and 5 boys) in the ages 2-15 years were presented to the Paediatric Emergency Department in Woolwich (UK). From March–September 2013 their burns were treated with L-Mesitran Hydro and Border with very good (cosmetic) results. Erythema was reduced, none of the children developed signs of wound infection, and pain reduced over time. Feedback from clinicians, parents and children was overall positive.2013 Belcher J Case report Lower leg ulcer 1 The use of L-Mesitran Net contributed to the autoly-tic debridement of the necrotic tissue on the lower leg wound of the patient. The honey was acceptable to the

of the success of this product it is an option that is now frequently used and included in the wound management formulary of the author.

See our website forother Marketing &

Reference Materialsand Related Links!

Dynarex L-Mesitran Honey