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DRUGS (outside you) vs. TOXICOLOGY (inside you)

DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

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Page 1: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

DRUGS (outside you)

vs. TOXICOLOGY

(inside you)

Page 2: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Importance to Forensic Science

• 75% of evidence being examined in forensic laboratories is drug-related.

Evidence from a drug bust in Hawaii, 6-26-06

Page 3: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Costs

To Society• $110 billion/year• Drug-related

violence and crime– 75% of males

arrested in NY tested positive for drugs

Page 4: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Costs

To Families• Violence and abuse

– 1/4 -1/2 domestic violence is drug related

– 81% of child abuse or neglect is drug related

• 3.2% of pregnant women use drug regularly

Page 5: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Costs to the BodyMeth as an example

Page 6: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Faces of Meth

To the individual

Multnahoma Sheriff’s Office

http://www.drugfree.org/Portal/DrugIssue/MethResources/faces/index.html

Costs

Page 7: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

What is a “drug”

• Natural or synthetic

• Affect psychology or physiology

• Most produced legitimately for Rx

• If taken just for pleasure = “illicit drug” or “drugs of abuse”

• If taken in excess causing illness or death = poison

Page 8: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Drugs that are restricted by law = “Controlled Substances”

Controlled Substances Act of 1970 Lists illegal drugs, their category and

their penalty for possession, sale or use.

• Five categories of controlled drugs

Page 9: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Categories Schedule I— high potential for abuse; no currently acceptable

medical use in the US; a lack of accepted safety for use under medical supervision

Schedule II— high potential for abuse; a currently accepted medical use with severe restrictions; abuse may lead to severe psychological or physical dependence

Schedule III— lower potential for abuse than the drugs in I or II; a currently accepted medical use in the US; abuse may lead to moderate physical dependence or high psychological dependence

Schedule IV— low potential for abuse relative to drugs in III; a currently accepted medical use in the US; abuse may lead to limited physical or psychological dependence relative to drugs in III

Schedule V— low potential for abuse relative to drugs in IV; currently accepted medical use in the US; abuse may lead to limited physical or psychological dependence relative to drugs in IV

Page 10: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule I — Heroin

White

Off-White

Brown

Page 11: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule I - LSD

Page 12: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule I - marijuana

Page 13: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule II—cocaine

Cocaine in powder form

Crack cocaine

Cocoa leaves

Crack and powder

Page 14: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule II - morphine

Various Forms

Page 15: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule II - amphetamines (including methamphetamines)

Amphetamines

Methamphetamines

Page 16: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule II - PCP

Page 17: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule II - Ritalin

Page 18: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule III—intermediate acting barbiturates

Page 19: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule III - anabolic steroids

Page 20: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule III - ketamine

Page 21: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule IV—other stimulants and depressants including Valium, Xanan, Librium

Page 22: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule IV - phenobarbital

Page 23: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule IV - Darvon

Page 24: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Controlled Substances Examples

Schedule V—codeine found in low doses in cough medicines

Cough syrup with DMX

DXM is a synthetically produced substance that is chemically related to codeine, though it is not an opiate.

Page 25: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

Hallucinogens

Mostly naturally occurring

Marijuana most widely used – decreases ability to concentrate, slows reactions, impairs coordination.

Page 26: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

Hallucinogens

LSD – from fungus Ergot- extremely dangerous. Causes psychosis, falshbacks, impaired memory & attention span. Possible teratogen.

Page 27: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

Hallucinogens

MDMA – Or “ectasy” (methylenedioxymethamphetamine) is synthetic. Causes stimulation and hallucinations, confusion, depression, addiction, severe anxiety, paranoia – sometimes even weeks after taking. Long term brain damage.

Page 28: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

Hallucinogens

Ketamine - (“Special K”) – legitimately used as an animal tranquilizer. A powerful hullucinogen. Causes delerum, amnisia, depression, and long-term memory difficulties.

Page 29: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

StimulantsAct on CNS and increases

energy level while decreasing appetite and fatigue. Problems: increases anxiety, restlessness, and causes depression after it wears off.

Caffeine to amphetamines and methamphetamines.

Coacine – from leaf of cocoa plant. Used to be snorted as powder, now recrystalized “crack”. Highly addictive, causes anxiety, insomnia, weight loss, paranoia, mental deterioration.

Page 30: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

Narcotics Analgesics (pain

relievers) Legal OTCs like aspirin Illegal ones come from

opium from poppy flower 4-21% morphine from

which heroin is made highly addictive. Overdoses cause death

Page 31: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Classification- based on pharmacological effects

Depressants Alcohol

$40 billion industry in USA Not a controlled substance

Barbiturates (“downers”) Highly addictive Withdrawal is dangerous Small dose Rx used to

reduce anxiety and help sleep Quaaludes

Page 32: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

More Pretty Meth Pictures

Page 33: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

More Pretty Meth Pictures

Page 34: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

More Pretty Meth Pictures

Page 35: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

More Pretty Meth Pictures

Page 36: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

More Pretty Meth Pictures

Page 37: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

More Pretty Meth Pictures

Page 38: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

Drug Analysis

Microscopic crystaline structure

Spot Tests (use chemical indicators = presumptive precipitation test OR presumptive color test)

TLC (Thin layer chromatography)

Spectroscopy (tell by light wave absorbance)

Liquid chromatography (send liquid thorough a solid phase and see what comes out first, second, etc.)

Gas Chromatography/Mass Spectroscopy (separate in gaseous phase, then identify by mass)

Page 39: DRUGS (outside you) vs. TOXICOLOGY (inside you). Importance to Forensic Science 75% of evidence being examined in forensic laboratories is drug-related

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