2551

1 2

(Drug Interaction) 3

4 Actinomycin Adriamycin ( course)

Isotonic 5 5 5 2

3 2 5 5 ( )

10 BSC

: ( Surgical Latex) 2 ( Lint Free-Low permeability) : BSC : Luer-Lock : (Aseptic Technique) 18 20 vials Negative Pressure Technique ampules ampule

Vesicant Actinomycin D, Doxorubicin, Mitomycin C, Vincristine (Leak) OSHA

: 2 surgical mask : : (distal part) (scalp vein needle) 21 23

15 20 6 3

1. 1.1 1.2

1.3

1.4

1.5

1.6 2

2.

2.1 2.2 2 2.3

Body Surface Area : BSA = [(4w+7)/(w+90)] X M2, W = . 2.4 2.5 Vincristine

2.6

2.7 2.8

2.9 Doxorubicin 1 mg/ml Endoxan 200 mg/10 ml

2.10 Syringe 2.11 Emergency set 2.12

3.

( 48 ) 100,000 1,500

( Creatinine 1.5 mg/dl) ( Cisplatin Methotrexate)

3.1 3.2 3.3 3.4 3.5 3.6

4. 4.1 Vesicant ( ) 4.2

4.3 2 3 Vial vesicant 2 3

4.4 (Slow leak) Vesicant

4.5 0.9% NSS 5 10 ml

4.6 4.7 Vesicant 4.8 (Direct push)

4.9

4.10 4.11 25 ml (Flush)

4.12 4.13 Vesicant

4.14 Heparin 5. 5.1 10 60,000/ 5.2 5.3 8 10 2 Endoxan, Ifosfamide Methotrexate 5.4 5.5

1. 2. 3. 4. 5. 6. Flow Chart

1. 2. Spill kit Nitrile() 3. 4.

5.

6. 7.

Spill kit

1. Mask, 2. Nitrile () / Disposable glove 3. , 4. 5. , 6.

70% detergent " " "" () (incineration) pH detergent pH "" inactivate detergent

( )

- 11.00 . - 14.00 . - - Antidote () - - 11.00 12.00 . - 14.00 15.00 . - 12.00 . - 14.00 .

1. Disposable glove Nitrile Glove free powder Mask

2. Aseptic technique 3. (Class II Biologic Safely Cabinet)

Alcohol 70%

4. Disposable syringe Syringe

Physician order sheet

5. Gauze, Syringe, Needle, Alcohol

6. 7.

7.1 Ampoule - Ampoule Gauze Alcohol 70% - Ampoule - Ampoule Gauze - Ampoule Ampoule - Ampoule Ampoule Syringe

7.2 Vial - Gauze Alcohol 70% - Vial Vial Vial - Syringe Vial Vial - Syringe Vial - 45 - Vial - Plunger Vial , Vial

8. - Ampoule Ampoule - Vial Vial Vial Syringe Parafilm Gauze

9. -

- 0.9% Normal Saline Solution (NSS) - Alcohol - Mask Syringe