BIOMEDICAL

Biomedical Hands in Designing life!!!!

Presentation Driving Thought!!

GET READY For THE

SCINTILLATING

EXPERIENCE!!!

Biomedical on NI platform

Role of Virtual Instrumentation

• User-friendly GUI for experiments and analysis

• Modular development scheme

• Flexibility/adaptability

Relating Heart to waveform

Advantages using NI

products

• Efficient and cost-effective way of acquiring and analyzing these signals.

• The advanced analysis techniques becoming invaluable to the practicing becoming invaluable to the practicing physician

• Diagnostic decision accurate.

• Lot of in build signal processing algorithms

• Filtering biomedical signals in different ways is a challenge that has to be solved.

Introduction to DAQ

• Data Acquisition – “Sampling of the real world to generate data that can be

analyzed and presented by a computer.”

Biomedical Fields for DAQ

• Common mechanical stimuli

• Pressures, flows, temperatures

• Biopotentials

• ECG, EMG, ERG, EEG, ENG, etc

• µV/mV levels, > 20 kHz sample rate

• Imaging techniques

• Echocardiogram, blood vessel contraction

• Edge detection, microscopic imaging

• Clinical instrumentation

• Acquisition from existing equipment (mostly serial)

Work at CBME, IIT Delhi on

National Instruments Platform

Brain-Computer interface using

Electroencephalograph(EEG)

Brain Computer Interface using

Peripheral Blood Flow Measure

Photoplethysmograph (PPG) Impedance Plethysmograph (IPG)

EOG Signal Analysis –

Horizontal Eye Movement

`

Synergy based Adaptive Prosthesis for Unilateral

Transfemoral amputee

Correlation

Regression

Artificial Neural Network

Fuzzy Logic

Dynamic Modeling (State Variable Approach)

Prosthesis Electronic mechanism

Mental

Task

`NetworkWireless transmission of

signals

Markers Position Patella movement monitoring

Study of muscle fatigue resulting from different load/bag

carrying positions, amongst school children

�Changes in gait pattern

�Gait kineticsoGravity

oInertia

oJoint reaction

oGround reaction

oMuscles and other joint

structures

�Gait kinematicsoExtent, speed and direction of

movement of joints or body

segments

Load carrying positions

US- 17.7% Body Weight

Italy-20% BW

Hong Kong-20% BW

Australia-10% BW

India- 10% = 2.6 BW

Fatigue, muscle soreness, back pain, numbness, shoulder pain,

Spinal Deformity

Grimmer et al., 1999;

Negrini and Carabalona,2002;

Pascoe et al., 1997;

Sheir-Neiss et al., 2003

Positioning the backpack on the upper spine

has thelargest negative effect on posture,

which can effect the development of the spine.

segments

oGoniometric analysis

oObservational gait analysis

oStride analysisStep length

Stride length

Velocity

Cadence

�Gait changes: Effect of

loads on the walking pattern

�Forward lean trunk:Effect on spine, shoulders, yolk

and neck muscles

No pattern

vision

•Acuity:6/36

•Motion

sensitivity

•Acuity:6/30

•Motion

sensitivity

•Shape

matching

•Acuity:6/30

•Motion

sensitivity

•Shape

matching

•Color

naming

•Acuity:6/24

•Motion

sensitivity

•Shape

matching

•Color

naming

•Face

detection

•Acuity:6/18

•Motion

sensitivity

•Shape

matching

•Color naming

•Face detection

•Object

recognition

Cortical Reorganization after Sight Onset

Of Cataract Blind Children

Sight

onsetTime

Nadi YantraNadi YantraNadi YantraNadi Yantra – A non-invasive

Diagnostic tool

Physio-Mouse

PPGPPG

IPG

GSR

Temp sensor

Finger Recog.

Nasal Dominance

• Nasal Dominance Tester (NDT) based on Piezo sensor

developed at CBME-IITD

LabVIEW based Pulse-oximeter

Pulse-Oximetry sensorPulse-Oximetry sensor

LabVIEW Block diagram of Pulse-OximeterResult

itie Product

Biomedical Amplifier (ECG, EEG, EMG, EOG) and Data Acquisition software using LabVIEW (works with different DAQ cards of NI)

CSF Dynamics

HP ABF

ATARCM

CBF VBF VS

VT

ACOP CNST CSFF

IP

Pulmonary Data Acquisition

(Others work)

• Classical Pulmonary Function Testing•

Using Graphical System

Design for Tumor Treatment

NI CompactRIO platform, NI

LabVIEW Real-Time, and the

LabVIEW FPGA Module to

develop a flexible and reliable GUI

and control system under extreme

Using the off-the-shelf Compact RIO

platform, Sanarus was able to quickly

develop a working prototype

and control system under extreme

time-to-market pressure to deliver

a device that would dramatically

reduce the emotional and physical

discomfort of patients undergoing

tumor treatment.

Further Applications

� Artificial intelligence programming with LabVIEW: genetic algorithms for instrumentation control and optimization

� Comparison of STFT and wavelet transform methods in determining epileptic seizure methods in determining epileptic seizure activity in EEG signals for real-time application:

� Virtual instrumentation for human factors studies in surgery and anesthesia

� The Eye Tracker System – A System to

Measure and Record Saccadic Eye Movements

How are NI products being

used in Biomedical field….

• Automating a Capillary Electrophoresis DNA

Spectrometer with LabVIEW

• Lookout and FieldPoint Provide Around-the-Clock

Monitoring of Biotech Experiment Storage

Environments

• Celera Genomics Uses LabVIEW in Human Genome

Sequencing

• Endothelial Evaluation of Corneal Transplants by

Knowledge-Based Digital Image Processing

• Prototyping of a Digital Flow Cytometer the NI Way

• Development of a Virtual Instrument for Control and

Data Acquisition of a Cardiovascular Pulse

Duplicator System Using LabVIEW

Using LabVIEW for Heart Rate

Variability Analysis

• HRV analysis a quantitative marker of the autonomic

nervous system (ANS)

UPCOMING BOOK!

Biomedical Series

Authors:Prof. Sneh Anand

Dr. Jayashree SantoshMr. Sanjeev Kubakaddi

Biomedical Engineering Biomedical Engineering Biomedical Engineering Biomedical Engineering ---- A practical approach to LabVIEWA practical approach to LabVIEWA practical approach to LabVIEWA practical approach to LabVIEW

Coming to the trailing end…

RIDES HAVE ENDED, IT IS NOW FOR US TO RIDES HAVE ENDED, IT IS NOW FOR US TO RIDES HAVE ENDED, IT IS NOW FOR US TO RIDES HAVE ENDED, IT IS NOW FOR US TO

MAKE IT MORE REALISTICMAKE IT MORE REALISTICMAKE IT MORE REALISTICMAKE IT MORE REALISTIC

LETS JOIN HANDS AND WORK TOWARDS LETS JOIN HANDS AND WORK TOWARDS LETS JOIN HANDS AND WORK TOWARDS LETS JOIN HANDS AND WORK TOWARDS

MAKING IT A MUCH POPULAR FIELD!!!!!!MAKING IT A MUCH POPULAR FIELD!!!!!!MAKING IT A MUCH POPULAR FIELD!!!!!!MAKING IT A MUCH POPULAR FIELD!!!!!!

“Technology, unlike science, is a group

activity. It is not based on individual activity. It is not based on individual

intelligence, but on the interaction

of many people”(H.E. Dr. A. P. J. Abdul Kalam, from “Wings of Fire”)