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Dr.F.Shariati

Dr. F.Shariati

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Dr. F.Shariati. DERMATITIS AND ECZEMA. Topics discussed. 􀂄 Diagnosis of eczema 􀂄 Incidence 􀂄 Aggravators 􀂄 History and assessment 􀂄 Treatments 􀂄 Clinical Cases. TERMINOLOGY. Eczema = Greek term “To boil over” - PowerPoint PPT Presentation

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Page 1: Dr. F.Shariati

DrFShariati

DERMATITIS AND ECZEMADERMATITIS AND ECZEMA

1048708 Diagnosis of eczema1048708 Incidence1048708 Aggravators1048708 History and assessment1048708 Treatments1048708 Clinical Cases

Topics discussed

TERMINOLOGY

Eczema =

Greek term ldquoTo boil overrdquo

Usually refers to severely inflamed dermatitis and the signs and symptoms associated with such an acute process (itching sting burning of the skin with

drainage from lesions)

Types of common eczemasbull Atopic eczema (infantile e flexural e atopic dermatitis) bull Seborrhoeic dermatitis (cradle capldquoin infants)bull Contact dermatitis is of two types(Allergic contact dermatitis

` Irritant contact dermatitis)bull Xerotic eczema (asteatotic e e craquele or craquelatum

winter itch pruritus hiemalis)

Less common eczemas bull Dyshidrosis (dyshidrotic e pompholyx vesicular)

(palmoplantar dermatitis)bull Discoid eczema (nummular e exudative e microbial e)bull Venous eczema (gravitational e stasis dermatitis varicose e)bull Neurodermatitis (lichen simplex chronicus localized scratch

dermatitis)bull Autoeczematization (id reaction autosensitization)bull Dermatitis herpetiformis (Duhringrsquos Disease)

Types of common eczemas

Clinical classification

bull Acute eczema

bull Subacute eczema

bull Chronic eczema

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 2: Dr. F.Shariati

DERMATITIS AND ECZEMADERMATITIS AND ECZEMA

1048708 Diagnosis of eczema1048708 Incidence1048708 Aggravators1048708 History and assessment1048708 Treatments1048708 Clinical Cases

Topics discussed

TERMINOLOGY

Eczema =

Greek term ldquoTo boil overrdquo

Usually refers to severely inflamed dermatitis and the signs and symptoms associated with such an acute process (itching sting burning of the skin with

drainage from lesions)

Types of common eczemasbull Atopic eczema (infantile e flexural e atopic dermatitis) bull Seborrhoeic dermatitis (cradle capldquoin infants)bull Contact dermatitis is of two types(Allergic contact dermatitis

` Irritant contact dermatitis)bull Xerotic eczema (asteatotic e e craquele or craquelatum

winter itch pruritus hiemalis)

Less common eczemas bull Dyshidrosis (dyshidrotic e pompholyx vesicular)

(palmoplantar dermatitis)bull Discoid eczema (nummular e exudative e microbial e)bull Venous eczema (gravitational e stasis dermatitis varicose e)bull Neurodermatitis (lichen simplex chronicus localized scratch

dermatitis)bull Autoeczematization (id reaction autosensitization)bull Dermatitis herpetiformis (Duhringrsquos Disease)

Types of common eczemas

Clinical classification

bull Acute eczema

bull Subacute eczema

bull Chronic eczema

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 3: Dr. F.Shariati

1048708 Diagnosis of eczema1048708 Incidence1048708 Aggravators1048708 History and assessment1048708 Treatments1048708 Clinical Cases

Topics discussed

TERMINOLOGY

Eczema =

Greek term ldquoTo boil overrdquo

Usually refers to severely inflamed dermatitis and the signs and symptoms associated with such an acute process (itching sting burning of the skin with

drainage from lesions)

Types of common eczemasbull Atopic eczema (infantile e flexural e atopic dermatitis) bull Seborrhoeic dermatitis (cradle capldquoin infants)bull Contact dermatitis is of two types(Allergic contact dermatitis

` Irritant contact dermatitis)bull Xerotic eczema (asteatotic e e craquele or craquelatum

winter itch pruritus hiemalis)

Less common eczemas bull Dyshidrosis (dyshidrotic e pompholyx vesicular)

(palmoplantar dermatitis)bull Discoid eczema (nummular e exudative e microbial e)bull Venous eczema (gravitational e stasis dermatitis varicose e)bull Neurodermatitis (lichen simplex chronicus localized scratch

dermatitis)bull Autoeczematization (id reaction autosensitization)bull Dermatitis herpetiformis (Duhringrsquos Disease)

Types of common eczemas

Clinical classification

bull Acute eczema

bull Subacute eczema

bull Chronic eczema

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 4: Dr. F.Shariati

TERMINOLOGY

Eczema =

Greek term ldquoTo boil overrdquo

Usually refers to severely inflamed dermatitis and the signs and symptoms associated with such an acute process (itching sting burning of the skin with

drainage from lesions)

Types of common eczemasbull Atopic eczema (infantile e flexural e atopic dermatitis) bull Seborrhoeic dermatitis (cradle capldquoin infants)bull Contact dermatitis is of two types(Allergic contact dermatitis

` Irritant contact dermatitis)bull Xerotic eczema (asteatotic e e craquele or craquelatum

winter itch pruritus hiemalis)

Less common eczemas bull Dyshidrosis (dyshidrotic e pompholyx vesicular)

(palmoplantar dermatitis)bull Discoid eczema (nummular e exudative e microbial e)bull Venous eczema (gravitational e stasis dermatitis varicose e)bull Neurodermatitis (lichen simplex chronicus localized scratch

dermatitis)bull Autoeczematization (id reaction autosensitization)bull Dermatitis herpetiformis (Duhringrsquos Disease)

Types of common eczemas

Clinical classification

bull Acute eczema

bull Subacute eczema

bull Chronic eczema

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 5: Dr. F.Shariati

Types of common eczemasbull Atopic eczema (infantile e flexural e atopic dermatitis) bull Seborrhoeic dermatitis (cradle capldquoin infants)bull Contact dermatitis is of two types(Allergic contact dermatitis

` Irritant contact dermatitis)bull Xerotic eczema (asteatotic e e craquele or craquelatum

winter itch pruritus hiemalis)

Less common eczemas bull Dyshidrosis (dyshidrotic e pompholyx vesicular)

(palmoplantar dermatitis)bull Discoid eczema (nummular e exudative e microbial e)bull Venous eczema (gravitational e stasis dermatitis varicose e)bull Neurodermatitis (lichen simplex chronicus localized scratch

dermatitis)bull Autoeczematization (id reaction autosensitization)bull Dermatitis herpetiformis (Duhringrsquos Disease)

Types of common eczemas

Clinical classification

bull Acute eczema

bull Subacute eczema

bull Chronic eczema

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 6: Dr. F.Shariati

Clinical classification

bull Acute eczema

bull Subacute eczema

bull Chronic eczema

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 7: Dr. F.Shariati

CARDINAL FEATURES OF INFLAMMATIONampeczema

bull Calor (warmth) - increased blood flow

bull Rubor (redness) -dilated blood vessels

bull Dolor (pain)- irritation of nerves in inflamed tissues

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 8: Dr. F.Shariati

bull Serum IgE levels

bull Skin prick tests(Allergy test)

bull Skin patch tests

bull RAST(checks to see if the body is producing

antibodies against common things like house

dustmitepollenscat and dog hair and food

substances)

bull Skin biopsy

INVESTIGATIONS

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 9: Dr. F.Shariati

Patch Test

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 10: Dr. F.Shariati

Skin biopsy

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 11: Dr. F.Shariati

Xerotic eczema

(Charlesworth Am J Med 2002)

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 12: Dr. F.Shariati

CHILDHOOD ECZEMA

Atopic Eczema

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 13: Dr. F.Shariati

Infantile stage ( 0-2 years ) tends to start around 3-6 monthsUsually affects the face

wristsnappy area and when severe every part of the bodyOften gets infected

Childhood stage( 2-12 years )the skin starts to become dry cracked and thickenedUsually

affects the elbowsback of kneesankles and back of earsSevere thickening of the skin is

very common in Afro-Caribbeans and Asians

Adolescent and adult phase (puberty onwards) lichenification of the skin is very

prominent nowAffects the elbowsknees neck and bottom of the eyes

STAGES of Atopic EczemaPHASES

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 14: Dr. F.Shariati

Distribution

Infantile stage

adult phase

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 15: Dr. F.Shariati

Atopic Derm Adults

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 16: Dr. F.Shariati

Hand Eczema

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 17: Dr. F.Shariati

Foot Eczema

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 18: Dr. F.Shariati

lichenification of the skin

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 19: Dr. F.Shariati

lichenification of the skin

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 20: Dr. F.Shariati

Must haveMajor Features

itchy skin

family history of atopy

typical picture( facial flexures lichenification)

Plus three or more of the followingMinor Features

Xerosisichthyosishyper linear palms keratosis pilaris

periaricular fissuresdennie-morgan lines

chronic scalp scalingpityriasis albacataract

UK Diagnostic criteria Sampson et al

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 21: Dr. F.Shariati

Associated Findings

bull Pityriasis alba

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 22: Dr. F.Shariati

Associated Findings

bull Xerosis

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 23: Dr. F.Shariati

Associated Findings

bull Keratosis Pilaris

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 24: Dr. F.Shariati

Associated Findings

bull Ichthyosis

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 25: Dr. F.Shariati

Hyperlinear Palmar Creases

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 26: Dr. F.Shariati

1048708 VERY 10-20 of children in developed countries (Harper et al2000)1048708 Incidence has trebled over the last 30 years (Harper et al

2000)1048708 Positive correlations of eczema with higher social classes

and airpollution has been confirmed (Simpson Hanifin 2005)

1048708 80 of children will develop eczema in 1st year1048708 50 of children will clear by 2 years of age1048708 85 of children will clear by 5 years of age1048708 About 5 of children with eczema will continue into adulthood

How common is Atopic Eczema

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 27: Dr. F.Shariati

1048708 Onset after 2 years of age (Vickers)1048708 Severe eczema in infancy1048708 Atypical location for age of the patient (Eczema to extensors wrists and hands to be more prone to persistence of eczema)1048708 Severity and duration of eczema are correlated to

the incidence of asthma1048708 Biparental history of atopy have shown to be unfavourable

Factors influencing poor prognosis Atopic Eczema

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 28: Dr. F.Shariati

1048708 Intractable itch1048708 Sleep depravation1048708 Disruption to family life1048708 Schoolwork absenteeism1048708 Parental marriage problems1048708 Chronic disease1048708 Teasing1048708 Low self esteem

Effects on Life Atopic Eczema

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 29: Dr. F.Shariati

1048708 Heat1048708 Dry skin and environment1048708 Prickle1048708 Allergies1048708 Irritants1048708 Infection1048708 Saliva1048708 Water

What aggravates Atopic Eczema

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 30: Dr. F.Shariati

1048708 Too many clothes1048708 Hot baths gt29 degrees1048708 Too many blankets1048708 Sportrunning around1048708 Hot cars1048708 Heaters1048708 Hot school classrooms

What makes eczema hot and itchy

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 31: Dr. F.Shariati

1048708 Soap use bath oils or washes1048708 Air blowing heaters1048708 Swimming pools1048708 Australia1048708 Therefore apply moisturiser from top to toe regularly and

more often when flaring

What makes eczema dry and itchy

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 32: Dr. F.Shariati

1048708 Animal hairdander1048708 Woolen clothes1048708 Sharp seams1048708 Tags1048708dust mitesmolds1048708 rough fabrics

What prickles eczema and makes it itchy

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 33: Dr. F.Shariati

Diagnosis

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 34: Dr. F.Shariati

First appointment is important in managing the eczema effectively and gain the trust of the patient and family

1048708 Family history1048708 Coexisting atopic disease1048708 Immunization1048708 Allergies tests diet manipulation and adequacy1048708 Growth1048708 Previous treatments used and outcomes1048708 Most distressing element1048708 Sleep disturbance1048708 Environmental aggravators assess heatprickledryness1048708 Effect on family life school1048708 Parents expectations from treatment1048708 YOUR expectation from treatment

Taking a good history

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 35: Dr. F.Shariati

Immunological Features of Atopic Dermatitis

bull Increased IgE productionbull Specific IgE to multiple antigensbull Increased basophil spontaneous histamine releasebull Decreased CD8 suppressorcytotoxic number and

functionbull Increased expression of CD 23 on mononuclear cellsbull macrophage activation with increased secretion of

GM-CSF(IL-5) PGE2 and IL-10bull Decreased numbers of IFN-gamma-secreting from Th

1-like cells

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 36: Dr. F.Shariati

1048708 Completely undress child1048708 Look for (SCORAD) httpadserversanteuniv-nantesfrScoradhtml )1048708 Extent (1-10)1048708 Infection (1-3)1048708 Broken skin (1-3)1048708 Erythema (1-3)1048708 Lichenification (1-3)1048708 Xerosis (1-3)1048708 Sleep pattern (1-10)1048708 Itch (1-10) Tottal 8-45

Assessment

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 37: Dr. F.Shariati

Assessment of severity

Clear ndash normal skin no evidence of active atopic eczema

Mild ndash areas of dry skin frequent itching +- small areas of redness

Moderate - areas of dry skin frequent itching redness +- excoriation and localised thickening

Severe ndash widespread areas of dry skin incessant itching redness (+- excoriation extensive skin

thickening bleeding oozing cracking

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 38: Dr. F.Shariati

Selection of treatment

This depends on

bull Disease severity

bull Age

bull Compliance

bull Efficacy

bull Safety data

bull Treatment costs

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 39: Dr. F.Shariati

Every day1048708 avoid aggravators1048708 moisturiser1048708 bath oil

Eczema TreatmentsTopical Treatments

Flaring Treatments 1048708 every day treatments +

1048708 steroid ointments1048708 wet dressings1048708 cool compresses1048708 antibiotics

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 40: Dr. F.Shariati

bull Antibiotics(for infected eczema)bull Antiviral agents(for eczema herpeticum)

bull Steroids are better avoided at this stagebull Antihistamines(for itching)

bull Pimecrolimus(thought to work by modifying the immune system)A new form of treatment but its

place in the management is not clearbull Patient may require admission as they

tend to be very unwell

Treatment (contrsquod)

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 41: Dr. F.Shariati

1048708 Within 24 hours if cortisone ointments are not clearing the eczema1048708 Child is waking at night1048708 Itchy1048708 Skin is thickened1048708 If there is blood on the sheets

When to use a wet dressing

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 42: Dr. F.Shariati

1048708 Reduce itch1048708 Treat Infection1048708 Moisturise the skin1048708 Protect the skin1048708 Promote sleep

Why apply wet dressings

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 43: Dr. F.Shariati

bull Phototherapy(using ultraviolet rays UVAnUVB)bull Immunity suppressing drugs(egoral steroidsazathioprineciclosporintacrolimus)bull Diet and nutrition (food allergy)bull Alternative therapies (Chinese medicine herbalism)

Second line treatment(severe cases)All these require specialist treatment in the

Hospital

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 44: Dr. F.Shariati

bull Viral infections like eczema herpeticumwarts and

molluscum contagiosum

bull Bacterial infections like impetigo(caused by staph aureus)

bull Cataracts

bull Growth retardation(10 of children are

affected but not thought to be related to steroid use)

COMPLICATIONS

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 45: Dr. F.Shariati

1048708 NO TOPICAL STEROIDS1048708 remove crusts1048708 +- oralIV acylovir1048708 most often oral keflex1048708 admission prn

Eczema Herpeticum

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 46: Dr. F.Shariati

1048708 REMOVE CRUSTS1048708 Oral keflex 10 days if well1048708 IV flucloxacillin ONLY if unwell or febrile1048708 General Eczema Care1048708 Admission prn

Bacterial infected eczema

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 47: Dr. F.Shariati

Education and information Explain cause and course of disease

Demonstrate quantities and frequency of treatments

Inform symptoms and signs of bacterial infections

How to recognise eczema herpeticum about use of complementary therapies explain have not be assessed for safety Should continue

to use emollients as well as complimentary therapies

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 48: Dr. F.Shariati

1048708 11 month old1048708 2 month past history of eczema1048708 Erythema1048708 itchy1048708 weeping1048708 waking every 1-2 hours overnight1048708 general flare

Case OneHistory

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 49: Dr. F.Shariati

1048708 Infected atopic eczema1048708 admission1048708 remove crustsweeping1048708 oral keflex1048708 cool compressing 1 hourly1048708 wet dressings to limbs bd1048708 baby soap1048708 2 layers of clothing to bed 1048708 heater in the bedroom 1048708 Diet breast fed full diet

Case oneWhat is the diagnosisWhat is the plan

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 50: Dr. F.Shariati

1048708 bath oil1048708 dermeze to face1048708 dermeze to limbs qid1048708 hydraderm to trunk qid1048708 wet t-shirt when red or itchy1048708 sigmacort 1 or elidel bd prn

Case oneplan continued

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 51: Dr. F.Shariati

1048708 Sigmacort 1 bd to face prn1048708 dermeze(50 soft 50 liquid paraffin) face qid1048708 Elocon nocte to limbs and trunk prn1048708 hydraderm to body qid1048708 keflex for 10days total1048708 cool compress prn1048708 bath oil1048708 follow up 1 -2 weeks

Case oneDischarge plan

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 52: Dr. F.Shariati

SUMMARYDermatitis is a common type of skin inflammationDermatitis is a common type of skin inflammation

There are many causes of dermatitisThere are many causes of dermatitis

Dermatitis disrupts the normal functions of skinDermatitis disrupts the normal functions of skin

Investigating causes of dermatitis is as important as Investigating causes of dermatitis is as important as using drug therapy using drug therapy

Traditional agents (glucocorticoids antihistamines) and Traditional agents (glucocorticoids antihistamines) and newer agents are available to treat this conditionnewer agents are available to treat this condition

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
  • Slide 9
  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
  • Slide 23
  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
  • Slide 30
  • Slide 31
  • Slide 32
  • Slide 33
  • Slide 34
  • Slide 35
  • Slide 36
  • Slide 37
  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
  • Slide 43
  • Slide 44
  • Slide 45
  • Slide 46
  • Slide 47
  • Slide 48
  • Slide 49
  • Education and information
  • Slide 51
  • Slide 52
  • Slide 53
  • Slide 54
  • SUMMARY
  • Slide 56
Page 53: Dr. F.Shariati

If you require a copy of this seminarplease Visit website atwwwkomakdarscom

Thank you

  • Slide 1
  • Slide 2
  • Slide 3
  • TERMINOLOGY
  • Slide 5
  • Clinical classification
  • CARDINAL FEATURES OF INFLAMMATIONampeczema
  • Slide 8
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  • Patch Test
  • Slide 11
  • Xerotic eczema
  • CHILDHOOD ECZEMA
  • Slide 14
  • Distribution
  • Slide 16
  • Slide 17
  • Atopic Derm Adults
  • Hand Eczema
  • Foot Eczema
  • lichenification of the skin
  • Slide 22
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  • Associated Findings
  • Slide 25
  • Slide 26
  • Slide 27
  • Hyperlinear Palmar Creases
  • Slide 29
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  • Immunological Features of Atopic Dermatitis
  • Slide 39
  • Assessment of severity
  • Selection of treatment
  • Slide 42
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  • Education and information
  • Slide 51
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  • SUMMARY
  • Slide 56