Dr Christine Lebrun Frenay, MD PhD, is a Neurologist and Oncologist. She is head in inflammatory neurological disorders clinical research unit and MS center in the university Nice (South East of France) hospital and Senior Professor at UTSW (Dallas, TX). She is member of French Neurological Society, French MS Society, which she was president and of European and American academies of Neurology. In 2008 she described the first cohort of a subclinical form of MS and subsequently co-founded with American, European and Turkish colleagues the RIS Consortium which expanded worldwide to collect a unique extensive patients cohort. Her particular research interest includes therapeutical and MRI studies in MS with a specific implication in the description of Radiologically Isolated Syndrome (RIS). She is participating in numerous clinical trials and research studies with international publications in neuro inflammatory diseases. She is a member of several editorial boards of scientific journals, scientific boards and involved in medical evaluations for MS patients' associations.