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Simulated Body Shape for Dose Determination in Phototherapy D.McG.Clarkson, Department of Clinical Physics and Bioengineering, UHCW NHS Trust, Coventry.

Dose Determination in Phototherapy D.McG.Clarkson, Department …resource.npl.co.uk/optical_radiation/ormclub/member/... · 2008. 2. 6. · Scottish UV dosimetry guidelines, "ScUViDo"

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  • Simulated Body Shape for Dose Determination in Phototherapy

    D.McG.Clarkson,Department of Clinical Physics and

    Bioengineering,UHCW NHS Trust, Coventry.

  • ISSUES

    Complex pattern of UV irradiance over a body surface.

    Bodies come in all shapes and sizes.

    Choice of timed dose or automated internal dosimetry.

    How effective is internal dosimetry

    system –

    if

    utilised?

  • ISSUES

    If checking cabinet irradiance, how is this best done –

    direct or

    indirect?

    How good is measurement technology accuracy -

    calibration and

    traceability?

  • Measurement Framework

    Moseley H.

    Scottish UV dosimetry

    guidelines, "ScUViDo". Photodermatol

    Photoimmunol

    Photomed. 2001 Oct;17(5):230-3.

    Taylor DK et al, Guidelines for dosimetry

    and calibration in ultraviolet radiation therapy: a report of a British Photodermatology

    Group workshop. Br J Dermatol. 2002

    May;146(5):755-63.

  • Measurement Techniques

    Martin CJ, Currie GD, Pye

    SD,The importance of radiometer angular response for ultraviolet phototherapy dosimetry. Phys Med Biol. 1999 Apr;44(4):843-55.

    Fulljames

    CA, Welsh AD.Measurement of patient dose in ultraviolet therapy using a phantom. : Br J Dermatol. 2000 Apr;142(4):748-51

    Currie GD, Evans AL, Smith D, Martin CJ, McCalman

    S, Bilsland

    D

    An automated dosimetry

    system for testing whole-body ultraviolet phototherapy cabinets. Phys Med Biol. 2001 Feb;46(2):333-46.

    Martin CJ, Clouting H, Aitken

    A A study of the correction factor for ultraviolet phototherapy dose measurements made by the indirect method. Br J Dermatol. 2003 Dec;149(6):1227-31.

    Clarkson DM, The use of simulated body shape for determination of patient dosimetry

    within whole body treatment cabinets, Phys. Med.

    Biol. 2006, 51, N51-N58

  • Unit ConstructionBody shape constructed by L. Franks of Radiotherapy Physics Section, Walsgrave Hospital.

    Styrofoam used extensively within Radiotherapy Physics

    Unit fabricated within three sections.

  • Body Shape Advantages

    Safety aspect of not being present in cabinet when measurements made.

    Reproducible positions makes comparisons more relevant.

    Potential to verify internal cabinet dosimetry

    systems.

    Potential for inter cabinet Comparisons.

  • Male(1)

    Female (2)

    Mean (1)+(2)

    Body Shape

    Mean height(cm)

    175.1 161.9 168.5 172.5

    Mean weight (Kg)

    83.8 70.1 76.95 -

    Est. Body surface area(m2)

    1.994 1.783 1.889 1.67

  • Item Value

    Total Height 172.5 cmMaximum Breadth 53.5 cmTotal weight 4.815 Kg

    Total Volume 0.1605 m2

    Density Styrofoam 30 Kg/m-3

    Major axis cross section area

    0.617 m2

    Minor axis cross section

    0.343 m2

    Material Styrofoam(building insulation)

  • Measurement System Bentham

    dmc150 spectroradiometer

    Detector DH-10 photomultiplier

    Calibration light source CL6-H

    Detector D6 diffuser f2 error 0.84% at 400 nm linked to 2 m fibre optic cable

    Slit width 1 nm

    Measurement interval 1 nm

  • Single parameter value for dosimetry.

  • Surface Uniformity

    ∑fi

    (h)Ai

    (h)Wi

    (h) dh

    --------------------------

    i = 0 to H

    ∑Ai(h) dh

    Where fi

    (h) = fraction of peak irradiance at height h

    Ai

    (h) = body shape area at height h per cm of height

    Wi

    (h) = arbitary weighting (

  • Variation of console/dmc150 reading with orientation

    of body shape

  • Coefficient of Overdosing

    MAX(reference -

    console irradiance value)/mean

    Where reference > console irradiance value

    Coefficient of Underdosing

    MAX(console irradiance value –

    reference)/mean

    Based on e.g. Rotation of body shape in cabinet in units of 90 degrees

  • Movement Compensation

    Describes gradient of function of reference measurements and of indicated console values. For two sites Ref1

    and Ref2 -

    eg front and rear of patient, a Positional Compensation term (PcxRef) can be described as :-

    PcxRef1

    = (dRef1

    /dx -

    dCon/dx)

    PcxRef2

    = (dRef1/dx -

    dCon/dx)

    Where Con is console indicated value.

    These terms can be understood in the sense of x axis in direction normal to entrance door. One side of patient appears to

    have some

    form of compensation -

    the other does not. These are constants of the physical design of the cabinet and the physical characteristics of the body shape.

  • Movement Compensation Sideways

    No compensation present

  • Considerations

    •Body shapes for ‘child’ -

    ‘teeny’ -

    ‘adult’.

    •Surface reflectance -

    application of paint an advantage -

    5% reflectance target in UV

    •Profile of detector.

  • Summary

    A rigid lightweight body shape has proved of value for routine Quality Control issues.

    The scope of such devices should encourage their development within the framework of a

    specific medical device standard for whole body treatment cabinets for ultra violet radiation.

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