* Antiseptic treatment* Barrier to infections* Insect repellent*
Fly Strike treatment
HEALTH AND HYGIENE (PTY) LTD (Reg. No. 94/00853/07)PO Box 906,
Florida Hills, 1716, South Africa
Tel: + 27 11 474 1668 Fax: +27 11 474 1670
www.healthandhygiene.co.za [email protected] THE BEST
FOR YOUR BEST FRIENDS!
GERMICIDAL WOUND SPRAY
VETERINARY PRACTICE
®®
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DOSAGE AND DIRECTIONS FOR USE• USE ONLY AS DIRECTED.• Remove all
organic material and clean the wound using an approved
irrigating
solution.• A maximum of 5 applications per animal with multiple
wounds (1- 2 sprays per wound).• Repeat twice at 4-5 day intervals
or as directed by a veterinarian.
PRECAUTIONS• Wear gloves and an eye mask during use.• Avoid
inhalation of spray mist.• Ingestion: DO NOT induce vomiting. Give
milk or water to drink.• Eye contact: Rinse eyes with water. Seek
medical advice if necessary.• IN CASE OF POISONING CONTACT A DOCTOR
AND MAKE THE PRODUCT
LABEL AVAILABLE.
WARNINGS• NO WITHDRAWAL PERIOD.• DO NOT MIX WITH SOAP AND OTHER
CHEMICALS.• Avoid contact with eyes.• Avoid contact with domestic
cats.• Keep out of reach of children, uniformed persons and pets.•
Although this product has been extensively tested under a large
variety of
conditions, failure thereof may ensue as a result of a wide
range of reasons. If this is suspected, seek veterinary advice and
notify the registration holder.• Flammable, keep away from naked
flames when spraying.• Cypermethrin is dangerous to fish or aquatic
life. Do not contaminate aquaria, fish
bowls, ponds or waterways with the insecticidal product.
PRESENTATIONHPE bottles of varying sizes. 100ml, 500ml (has a
trigger operated spray) and 5 litres.
IDENTIFICATIONClear pale straw liquid with ethanol odour.
Alternatively with a red soluble marker dye.
STORAGE INSTRUCTIONSo Store below 30 C in dry conditions and
away from direct sun.
AUTHORISATIONSouth Africa: DAFF, Act 36/1947, Reg. No. G3818USA:
FDA, MUMS Index, MIF 900-010UK: VMD, SAES
MANUFACTURED BYHealth and Hygiene (Pty) Ltd in accordance with
GMP License no. M7294 APVMA, SABS permit no.6656/99863
InsecticideInsecticideInsecticideWithWithWith
GermicidalWound Spraywith Insecticide
GermicidalWound Spraywith Insecticide
®
F10 GERMICIDAL WOUND SPRAY WITH INSECTICIDE (RTU)(Liquid, use as
is, in 100ml, 500 ml with trigger spray and 5 litre jerry cans.
Available in natural clear solution and with a red water soluble
dye)
Reg No. G3818 Act 36/1947 COMPOSITIONQuaternary ammonium and
biguanide compound
.................................................0,44%Non toxic
ampholytic surfactants and sequesterants
.............................................7,06%Cypermethrin
........................................................................................................0,25%Piperonyl
Butoxide
...............................................................................................1,25%Water
..............................................................................................................to
balance
INDICATIONSA topical application spot treatment spray as an
antiseptic and long-acting barrier to infection. For use in open
wound sites caused by e.g. trauma, muelsing, castration, de-budding
and de-horning. Also for abscesses, foot rot, dart wounds,
de-gloving injuries as well as over primary closure sites.
It incorporates an insecticide to repel insects from wound sites
and to repel insects such as biting flies (sweet itch) and ticks.
It is effective to eliminate infestations due to fly strike (the
larvae migrate out of the wound without the need for mechanical
elimination) whilst at the same time creating an effective
antiseptic barrier and effective repellent to further fly
strikes.
APPLICATIONField trials took place over 2 years and included
over 8000 animals across many species covering production animals
including cattle, sheep, goats ostriches, companion animals
including dogs and horses, exotics including rabbits, guinea pigs,
tortoises, hedgehogs, birds of prey and wildlife species including
Bactrian Camel, Leopard Tortoise, Black and White rhino, Bushbuck,
Blue Duiker, Mona monkey, Pygmy hippo, Axis deer, Red duiker,
Arabian oryx, Scimitar horned oryx, Eland, Waterbuck, Cape buffalo,
Fallow deer, Cape vulture, Nyala, Polar Bear, Mandrill, Ducks and
Sitatunga , large cats including lions, tigers, cheetah and snow
leopard.
The product demonstrated good long acting antimicrobial action,
in excess of 10 days on both open wounds and primary closure sites
which were maintained free of insects during the healing period due
to the insecticidal action. It was also found to be effective in
the treatment of wound infestations due to fly strike.
The product is water soluble and can be rinsed clear with
water.
ANTIMICROBIAL ACTIONThe antimicrobial action of the product is
based upon core actives of the F10 compound as used in other F10
antiseptic and disinfectant products.
At the concentrations in this product, the efficacy achieved is
> log5 (100,000 times) reduction in microbial counts against
gram positive and gram negative bacteria, as well as fungi, yeast
and moulds. F10 has proven virucidal effectiveness against both
enveloped and non-enveloped viruses.
INSECTICIDAL ACTIONThe insecticidal action is based upon
cypermethrin (a pyrethroid) and aided by piperonyl butoxide. In the
testing phases the indicator species used was Lucilia cuprina, a
commonly occurring blow fly species. As soon as the larvae were
sprayed they immediately began to migrate from the test site and
within 30 minutes were dead. Other tests on L. cuprina eggs
resulted in a 100% kill. The product was equally effective against
adult flies and showed a 77% kill in 15 minutes rising to 100%
within 30 minutes.
Cypermethrin is a broad spectrum insecticide and is effective
against other insects, e.g. biting flies, fleas, midges,
mosquitoes, and ticks.
RESIDUAL ACTIONResidual action tests showed the product was 100%
effective after 5 days. Extended field trials demonstrated that the
residual action could extend beyond 2 weeks. However the product is
water soluble and should be re-applied if the animal has been
washed or exposed to heavy rain.
TOXICOLOGYThese studies were carried out in accordance with the
test requirements as specified by the EPA. All studies were subject
to an independent GLP compliance audit.
Acute oral toxicity (rats) – >2000 to 5000mg/kgOPPTS 870.1100
– EPA category III
Acute dermal toxicity (rats) – > 5000mg/kgOPPTS 870.12000 –
EPA category III
Acute dermal irritation (guinea pigs) – very slight erytherma
(grade 1) OPPTS 870.2400 for a few hours but reversible within 24
hrs – EPA category IV
Acute eye irritation (rabbits) – after 24 hrs contact the cornea
OPPTS 870.2500 and iris showed no reaction. The eyelids and
nictating membranes were
graded 1 after 1 hour and were reversible after 72 hrs
– EPA category IV
Acute skin sensitization (guinea pigs) – no sensitizationOPPTS
870.200
Acute inhalation toxicity (rats) – LC50 > 2mg/litreOPPTS
870.200 – EPA category IV
STABILITYRepeat efficacy tests and chemical analysis confirm a
shelf life in excess of 3 years.
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