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[1] DOPAMINE Matt, Ashley, Andrea P.7. HERE IS A SHORT VIDEO... http://www.youtube.com/watch?v=FM- leD0Iyk4&list=PL5E58428F8D64E806&index=5 Interesting Facts / Diseases Parkinson's disease and drug addiction are some of the examples of problems associated with abnormal dopamine levels. Levels of dopamine in the brain, especially the prefrontal cortex, help in improved working memory Dopamine plays a role in pain processing in multiple levels of the central nervous system. Low levels of dopamine are associated with painful symptoms that frequently occur in Parkinson's disease. Dopamine is one of the neurotransmitters implicated in the control of nausea and vomiting Dopamine helps in focus and attention. Dopamine stabilizes the brain activity, regulated flow of information to other parts of the brain and controls movement. It plays a major part in addiction Neurotransmitter: A chemical that is released from a nerve cell which thereby transmits an impulse from a nerve cell to another nerve, muscle, organ, or other tissue. A neurotransmitter is a messenger of neurologic information from one cell to another. Neurons communicate information by movement of chemicals across a microscopic gap called the synapse. Neurotransmitters, which are chemicals located in the brain, are released from one neuron from the presynaptic nerve terminal . Neurotransmitters then go across the synapse , from this point the neurotransmitters can be accepted by the next neuron at a specialized site called a receptor. Drugs Cocaine and meth amphetamines inhibit the re- uptake of dopamine. Cocaine is a dopamine transporter blocker that inhibits dopamine uptake. Amphetamine increases the concentration of dopamine in the synaptic gap. They are similar in structure to dopamine, so can enter the presynaptic neuron via its dopamine transporters. By entering, amphetamines force dopamine molecules out of their storage vesicles. By increasing presence of dopamine both these lead to increased pleasurable feelings.

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Page 1: Dopamine P.7

[1]

DOPAMINEMatt, Ashley, Andrea P.7.

HERE IS A SHORT VIDEO...http://www.youtube.com/watch?v=FM-leD0Iyk4&list=PL5E58428F8D64E806&index=5

Interesting Facts / Diseases

Parkinson's disease and drug addiction are some of the examples of problems associated with abnormal dopamine levels.

Levels of dopamine in the brain, especially the prefrontal cortex, help in improved working memory

Dopamine plays a role in pain processing in multiple levels of the central nervous system. Low levels of dopamine are associated with painful symptoms that frequently occur in Parkinson's disease.

Dopamine is one of the neurotransmitters implicated in the control of nausea and vomitingDopamine helps in focus and attention.

Dopamine stabilizes the brain activity, regulated flow of information to other parts of the brain and controls movement. It plays a major part in addiction

Neurotransmitter: A chemical that is released from a nerve cell which thereby transmits an impulse from a nerve cell to another nerve, muscle, organ, or other tissue. A neurotransmitter is a messenger of neurologic information from one cell to another.

Neurons communicate information by movement of chemicals across a microscopic gap called the synapse. Neurotransmitters, which are chemicals located in the brain, are released from one neuron from the presynaptic nerve terminal . Neurotransmitters then go across the synapse, from this point the neurotransmitters can be accepted by the next neuron at a specialized site called a receptor.

Drugs

Cocaine and meth amphetamines inhibit the re-uptake of dopamine. Cocaine is a dopamine transporter blocker that inhibits dopamine uptake.Amphetamine increases the concentration of dopamine in the synaptic gap. They are similar in structure to dopamine, so can enter the presynaptic neuron via its dopamine transporters. By entering, amphetamines force dopamine molecules out of their storage vesicles. By increasing presence of dopamine both these lead to increased pleasurable feelings.

Page 2: Dopamine P.7

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Part it affects : BRAINHigh levels of dopamine in the brain are found in patients with attention deficit/hyperactivity disorder and Parkinson's patients treated with L-dopa, who exhibit impulsive behavior.Too much or too little dopamine in a brain area or areas can lead to undesirable effects, as can one brain area having too little or too much while the other brain area has toolittle or too much.

http://www.livestrong.com/article/297447-the-effects-of-dopamine-deficiency/#ixzz2Eg34uuqt

http://www.livestrong.com/article/408170-what-are-the-effects-of-too-much-dopamine/#ixzz2Eg2aZDEG

Excitatory DOPAMINE is our main focus neurotransmitter. When dopamine is either elevated or low – we can have focus issues such as not remembering where we put our keys, forgetting what a paragraph said when we just finished reading it or simply daydreaming and not being able to stay on task. Dopamine is also responsible for our drive or desire to get things done – or motivation. Stimulants such as medications for ADD/ADHD and caffeine cause dopamine to be pushed into the synapse so that focus is improved. Unfortunately, stimulating dopamine consistently can cause a depletion of dopamine over time.http://www.neurogistics.com/TheScience/WhatareNeurotransmi09CE.asp

Inhibitory DOPAMINE is a special neurotransmitter because it is considered to be both excitatory and inhibitory. Dopamine helps with depression as well as focus, which you will read about in the excitatory section.

Some of its notable functions are in:

• movement• memory• pleasurable

reward• behavior and

cognition• attention• inhibition of

prolactin production

• sleep• mood• learning