Dog bones-Congenital hip dysplasia 2nd OA

Congenital hip dysplasia-2nd OA, small head to neck ratio

Multi epiphyseal dysplasia (w/dwarfism) 2ndOA

Acromegaly=diabetes(inc GH) + 2nd OA

Acromegaly

Achrondoplasia-bowing and overgrowth of joint ends 2nd OA

Ochronosia-alkaptonuria (autosomal recessive) results in black discoloration of cartilage due to deposition of polymers of homogentisic acid.

Ochronosia-2nd OA vertebra patella

JRA

Hemophilia-2nd OA knee Recurrent hemarthroses lead to pannus

Hemophilia-2nd OA radial head

Hemophilia-2nd OA blue=Fe

Hemophilia-2nd OA ankylosis

Acute staphylococcal arthritis.

Acute hemorrhagic synovitis secondary to staphylococcal infection

Acute suppurative bacterial infection

Acute suppurative bacterial infection apple core-shaped remnant w/ residual exuberant synovial reaction around joint.

Acute gonococcal arthritis (common in wrist)

Lyme Dz

Lyme disease (erythema chronic migrans) skin

Vascular thickening w/ Lyme Dz

Lyme Dz-silver stain for spirochete

TB arthritis-pannus (can lead to ankylosis)

TB arthritis-giant cell

TB arthritis-Acid fast stain

RA-MP, PIP (spare DIP)

RA-ulnar deviation

Hypertrophic villous synovitis in RA.

Hypertrophic villous synovitis in RA.

Fibrinoid necrosis in synovium in RA (T cells)

RA-pannus

RA-pannus

RA-rice bodies

RA-rheumatoid nodule

RA-rheumatoid nodule

Rheumatoid nodule in lung shows typical fibrinoid necrosis.

Rheumatoid nodule in myocardium-conduction problem

Pericardium in patient with rheumatoid arthritis shows typical fibrinoid necrosis

Acute valvulitis from rheumatic fever (no arthritis)

Active rheumatoid vasculitis

Rhematoid vasculitis in a nerve biopsy

polyarteritis nodosa

giant cell arteritis

rheumatoid tendonitis

RA in spine

RA-Fibrinoid necrosis of intervertebral disc in cervical spine

RA in spine

RA-compress spinal cord

JRA

Still’s dz-Femoral head small and elongated due to inflammation.

Sago spleen-amyloid (AA) in RA

Kidney-amyloid (AA) in RA

Sjøgren’s syndrome

Sjøgren’s syndrome

Felty’s syndrome is a combo of vasculitis, hypersplenism, severe RA, and intractable leg ulcers.

Felty’s syndrome-big spleen

Anti-DNA protein antibody bound to nuclei after contact with serum from RA patient and staining with fluorescent anti-human IgG.

SLE patient-villous synovitis;also osteoporosis due to taking steroids

Necrosis of end of finger in patient with RA and cryoglobulinemia

Scleroderma

Scleroderma patient w/ circulating cryoglobulins and Raynaud’s phenomenon

ankylosing spondylitis

(bilateral sacroiliitis)

ankylosing spondylitis

Bone bridges=rigid spine

Chronic iritis in ankylosing spondylitis

acute synovitis in Reiter’s sydrome

Reiter’s syndrome

Reiter’s syndrome- balanitis circumscripti

psoriatic arthritis

psoriatic peripheral arthritis (arthritis mutilans)

psoriatic arthritis-hourglass distal phalange