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A Broad-Spectrum Computerized Neurocognitive Testing Platform Coupled with 50+ Clinical and

Quality Rating Instruments

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Enhance Your PracticeWith CNS Vital Signs Neurocognitive Testing Procedure!Objective I Valid I Reliable I Efficient I Reimbursable I Secure

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Does your Cognitive Testing Support Professional Guidelines?

* $ Represents Estimated National Average Practice Reimbursement

96130 $121

+96131After first hour

$91Testin

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od

es

Pro

fession

al Co

des

96112 $132Developmental

For more information refer to the CNS Vital Signs ‘Reimbursement Guide’, schedule a FREE TRAINING

WEBINAR at CNSVS.com or email support@cnsvs.com.

99483In-Clinic & Telehealth Codes

$283Cognitive Assessment & Care Planning

PDF

Optimize Care and Add Anti-Fragile, Incremental Revenue…

9613630 min of testing

$47

+96137After 31+min of testing

$42

1 2

Neuro Evaluation

Psych Evaluation

96132 $133

+96133After first hour

$103

Clinician Testing

Technician Testing

96116, 96121In-Clinic & Telehealth Codes

$97

9613830 min of testing

$37

+96139After 31+ min of testing

$37

Neurobehavioral Status

2

In-Clinic Testing

Telehealth “Remote” Testing

+

Additional Codes

DSM-5 Neurocognitive Disorder, Five Key Cognitive Domains Tested

Recommended Neurocognitive

Domains

Learning and Memory

Perceptual-Motor

Function

Executive Function

Social Cognition

Complex Attention

Language Cannot be tested on a computer.

Does your Cognitive Testing Assess the DSM-5 Neurocognitive Disorder Recommended Brain

Domains, help Collect MIPS Quality Measures and Required Reimbursement Elements?

CNS Vital Signs standardized neurocognitive testing is a non-invasive, reimbursable clinical procedure to efficiently and objectively assess a broad-spectrum of brain function domain performances under challenge (cognition stress test). Enabling the measuring of important clinical symptoms, behaviors, and comorbidities salient to the evaluation and ongoing management of many neurological, psychiatric and other conditions. Serial evaluation of neurocognition can help patients and caregivers navigate problems related to daily living, school or vocational work environment.

“Neurocognitive disorders - are characterized by decline from a previously attained level of cognitive functioning… Objective assessments are essential… The move to evaluate neurocognitive

*** Adapted From: Perminder S. Sachdev, Deborah Blacker, Dan G. Blazer, Mary Ganguli, Dilip V. Jeste, Jane S. Paulsen & Ronald C. Petersen: Classifying neurocognitive disorders: the DSM-5 approach: Nature Reviews Neurology volume 10, pages 634–642 (2014)

disorders as early as possible emerged from the recognition of a long predementia stage in neurodegenerative diseases, improvements in early detection, and the increasing emphasis on early intervention to prevent or postpone dementia…Evaluation criteria: Evidence of modest cognitive decline from a previous level of performance (longitudinal) in one or more cognitive domains…***”

Collecting Required Elements for Procedure Code 99483

Widely Reimbursed… Well Established Billing Codes

1

Select Testing Method

2

Select Tests or Test Panel

3

5

Baseline / Current Cognitive Status

View

Longitudinal View

Rating Instruments Neuropsychiatric Daily Function Sleep Falls

Custom configure test panels (cognitive tests and rating instruments) to optimize your

research, clinical, and quality care activities.

Use CNS VS Cognitive Care Plan Template

4

Easily Add Test Reports to EMR & Bill

Create Care Planand Provide Feedback

Conduct Required Elements Testing

Example

12

3

DOMAIN DASH

BOARD

DETA

ILED TEST R

ESULTS 

See Brief Interpretation Guide on the Next Page 3

Easy to Read… Immediate ReportingReports available in English, Spanish, Japanese, and Korean.

Longitudinally Track

4

The CNS Vital Signs results are presented in a DOMAIN DASHBOARD and DETAILED TEST report format immediately following the brief testing session.Standardized evaluation of neurocognitive and behavioural issues provides a systematic and efficient method of collecting valid and reliable clinical measures currently recommended by most neuro-psych guidelines. Altogether, CNS Vital Signs computerized testing can facilitate a more complete assessment and provide a basis for patient and family feedback. The colorful auto-scored reports are designed to present and share with patients, families, and caregivers.

Additional Clinical and Practice Benefits

Millisecond Precision Hundreds of Peer - Reviewed

Publications Embedded Test Validity

Indicators Millions of Tests Given

Worldwide Since 2006 Over 50 Languages Unlimited Alternate Forms

for Serial Testing No Ceiling Effect… Open

Ended Performance to Identify Superior Subjects

Modular… Easily Configured Custom Testing Panels and Platform

Enhanced Auditability with Automated Systematic Documentation

HIPAA Secure, Data back-up and Data export

Broad Deployment… Solutions for small, medium and large practices, integrated delivery systems, high security environments such as FDA sponsored clinical research, Military, VA Hospitals, Academic Medical Centers, across thousands of clinician and research users worldwide

Test Evaluation Criteria: The CNS VS reports are logical and intuitive making the interpretation by a health professional relatively straightforward. CNS Vital Signs has taken a LIFESPAN approach collecting a large peer neurocognitive normative reference group from ages 8 to 90. The normative comparison helps clinicians grade the level of neurocognitive impairment and compare the evidence of cognitive decline from a previous level of performance which can help rule-in or rule-out certain clinical conditions, help determine the level of impairment or track disease progression or improvement. Clinical insight into the cognitive status of a patient can come from impairment in one or more cognitive domains. Like any laboratory test, an abnormal result should be the occasion for further evaluation.

2Evaluate Validity: The Validity Indicator (VI) helps identify the possibility of an invalid test. Embedded measures helps evaluate whether the patient is manipulating testing performance for a secondary gain or they simply did not read the test instructions. Examples of secondary gain include: drug or disability seeking, academic accommodation, malingering, symptom feigning, etc.

3Evaluate Severity: The scores help identify cognitive deficits and their level of impairment. Assess even slight cognitive impairment (millisecond precision) providing immediate clinical insight into a patient’s cognitive deficits and level of impairment. This gives patients, family members and caregivers knowledge of cognitive domains that underpin the ability to conduct activities of daily living.

4 Evaluate Longitudinally: Track disease progression, outcomes, or treatment effects. Establish a baseline and serially assess cognitive clinical endpoints to aid in the monitoring and management of many clinical conditions and treatments e.g., measure the response to disease and treatment like MS, AD/HD & stimulants, rehabilitation efforts, and used to measure clinical outcomes.

Evaluate Pattern: Impairment pattern helps identify pathologies and possible comorbidities.The CNS VS cognitive pattern profiles (interpretation guide) may assist clinicians in the evaluation of neurological, psychiatric, and developmental disorders. CNS Vital Signs cognitive testing procedure provides valid and reliable clinical endpoints to help in the evaluation and management of patients.

1

Executive Function

03/28/2015 10/16/15 12/15/15

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Standard Score

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Easily Graph Longitudinal Results

One Key Difference – Measuring Cognitive Speed… “CNS Vital Signs is sensitive in detecting cognitive impairment …uses computerized forms of traditional tests such as Symbol Digit Modalities and Stroop …are easy to use, require significantly less time to administer, produce instant scoring and can incorporate alternate forms, necessary to minimize learning effect on follow-up. …also, the capacity to accurately-automatically quantify “speed factor” via multiple parameters such as reaction time, psychomotor speed, and processing speed, increasing their sensitivity in detecting even subtle changes in information processing speed.” ** **Cognitive Impairment in Relapsing Remitting and Secondary Progressive Multiple Sclerosis Patients:

Efficacy of a Computerized Cognitive Screening Battery; ISRN Neurology, 2014 Mar 13;2014:

Single Domain Example:  All Domains are Graphed

4

Evaluate & Manage… Optimize Your Practice Processes

Testing performance should be reviewed with knowledge of a patient's history and physical or diagnostic interview, lab tests, etc. to understand the context of the possible cognitive deficits. Examples of CNS VS use… Neurodegeneration

(Neurocognitive Disorder, MCI, Multiple Sclerosis, Parkinson’s, Sleep, etc.)

Neurotraumatic (mTBI, Concussion, TBI Rehabilitation)

Neurodevelopmental (AD/HD, Asperger’s, etc.)

Neuropsychiatric (ADD, SUD, Bipolar, Depression, PTSD,Schizophrenia, Anxiety, etc.)

Other: HIV-HAND, Cancer Cognition, Chronic Pain Fibro-Fog,Encephalopathy, Metabolic / Diabetes, Cardiovascular, Prion or Lyme Disease, Human Performance, Neurotoxicity, Diet & Exercise, Medication Effects, etc.

■ Learning Words■ Memory for Words■ Word Recognition■ Immediate and Delayed

Recall

Verbal Memory (VBM)

Approx. 3 Minutes

■ Learning Shapes■ Memory for Shapes■ Shapes Recognition■ Immediate and Delayed

Recall

Visual Memory

(VIM)Approx. 3 Minutes

■ Motor Speed ■ Fine Motor Control

Finger Tapping

(FTT)Approx. 2 Minutes

■ Complex Information Processing Accuracy

■ Complex Attention ■ Visual-Perceptual Speed■ Information Processing

Speed

Symbol Digit Coding(SDC)

Approx. 4 Minutes

■ Simple Reaction Time ■ Complex Reaction Time■ Stroop Reaction Time ■ Inhibition / Disinhibition■ Frontal or Executive Skills

StroopTest(ST)

Approx. 4 - 5 Minutes

■ Executive Function■ Shifting Sets: Rules,

Categories, & Rapid Decision Making

■ Reaction Time

Shifting Attention

(SAT)Approx. 2.5 Minutes

■ Social Cognition or Emotional Acuity

■ Choice Reaction Time

Perception of Emotions

(POET)Approx. 2 Minutes

■ Reasoning■ Reasoning Recognition

Speed

Non-Verbal Reasoning

(NVRT)Approx. 3.5 Minutes

■ Sustained Attention■ Working Memory

4-Part Continuous

Performance(FPCPT)

Approx. 7 Minutes

■ Sustained Attention■ Choice Reaction Time■ Impulsivity

Continuous Performance

(CPT)Approx. 5 Minutes

B

10 Normed Neurocognitive Tests… 50+ Rating Scales

Computerized versions of VENERABLE NEUROPSYCHOLOGICAL TESTS. Measures the SPEED and ACCURACY of a patient’s response. TOTAL TEST TIME depends on the number of tests and rating instruments selected. Modular testing panels can be custom configured according to clinical practice or research needs.

Pediatric - Adolescent Instruments:Developmental - Mental Health Pediatric Symptom Checklist (PSC-35, Youth and PSC-17) Vanderbilt ADHD Diagnostic Parent & Teacher Rating Scales Vanderbilt Assessment Follow-up Parent & Teacher Rating Scales PHQ-9 Depression & GAD-7 Anxiety DASS - Depression, Anxiety and Stress Scale 21 & 42 (14 years of age and up) Screen for Child Anxiety Related Disorders (SCARED) Child & Parent Version Social Anxiety Scale for Children and Adolescents (SASCA) Targeted Instruments Child Obsessive-Compulsive Disorder Inventory (OCD-C) Childhood Cancer Survivor Study Neurocognitive Questionnaire (CCSS) Neurobehavioral Symptom Inventory (NSI) DSM -5 PTSD Checklist (PCL-5) & Stressor Specific (PCL-S)Substance Abuse - SBIRT Drug Use Questionnaire (DAST) Alcohol Use Disorders Identification Test (AUDIT)

Adult Instruments:Health Risk - Mental Health Patient Health Questionnaire (PHQ-9) General Anxiety Disorder (GAD-7) DASS - Depression, Anxiety and Stress Scales 21 & 42 Zung Self-Rating Depression & Anxiety Scales Stanford Geriatric Depression Scales (SGDS) 15 & 25Targeted Instruments Quality of Life Medical Outcomes Survey (MOS) SF-36 Adult ADHD Self-Report Scale (ASRS-v1.1) Symptom Checklist DSM-5 PTSD Checklist (PCL-5), also the Civilian (PCL-C), Stressor Specific

(PCL-S) and Military (PCL-M) Fall Risk Questionnaire (FRQ) Health Assessment Questionnaire (HAQ) Disability Scale Modified Fatigue Impact Scale (MFIS) Neurobehavioral Symptom Inventory (NSI) Dizziness Handicap Inventory (DHI) Head Injury Questionnaire (HIQ) Memory Questionnaire (MEMQ) Adult Obsessive-Compulsive Disorder Inventory (OCD-A) MHE Questionnaire Combat Exposure Scale (CES) Life Events Checklist (LEC) Deployment Risk and Resiliency Inventories Life Habits Checklist Medical Symptoms Questionnaire (Past 30 Days) and (Past 48 Hours)Sleep Epworth Sleepiness Scale (ESS) Pittsburgh Sleep Quality Index (PSQI) Sedation Scale (SS) Alertness Rating Scale (ARS)Substance Abuse - SBIRT Drug Use Questionnaire (DAST) Alcohol Use Disorders Identification Test (AUDIT)Pain Numeric Pain Scale Pain Catastrophizing Scale (PCS)

CNS Vital Signs assessment platform includes 50+ medical and health rating instruments helping identify and systematically document PATIENTand INFORMANT ratings of symptoms, behaviors and comorbidities.

5Efficient testing for your patient needs and time constraints.

Fully Integrated System available with VS4 Local Computer Software Testing and Cloud-Based Online Testing Options

Amnestic MCI Baseline: 60-Year-Old Male Initial MMSE 25*

Amnestic MCI Longitudinal View: 60-Year-Old Male

Joe, a 60-year-old male is presenting with memory and concentration concerns and was given CNS Vital Signs Clinical Battery and scored below average compared to his peers in 6 of 11 cognitive domains. His lowest scores were in domains sensitive to amnestic (memory related) MCI. After considering the H&P, lab results, patient and informant memory questionnaire, sleep scales and the cognitive test results; Joe was referred for a sleep study. Later he was prescribed CPAP and appropriate therapy. CNS Vital Signs allowed a fine characterization of Joe’s clinical course, including apparent variation due to compliance with therapy. Patient and wife were positively influenced by revelation of objective cognitive testing performance, which proved useful in demonstrating probable effects of compliance.

03/12/2012 11/16/13 2/07/14

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3/16/13

NCI - Neurocognition Index

...Study included 107 postmenopausal women between the ages of 52 and 65 (mean 56.6 ± 3.5)

…Subjects were qualified as "normal" with MOCA scores between 26 and 30

...Findings revealed ApoE polymorphisms correlated to levels of cognitive function where as expected ε3/ε4, or ε4/ε4 scored poorly while ε2/ε3 groups scored much better.

Correlation to Biological Markers

Adapted from: Bojar, Iwona & Wójcik-Fatla, Angelina & Owoc, Alfred & Lewiński, Andrzej. (2012). Polymorphisms of apolipoprotein E gene and cognitive functions of postmenopausal women, measured by battery of computer tests - Central Nervous System Vital Signs. Neuro endocrinology letters. 33. 385-92.

Case Examples: MCI, DSM-5 Neurocognitive Disorder, Early Intervention

Psychomotor Speed

Complex AttentionCognitive Flexibility

CNS VS Correlation to Alzheimer’s ApoE Polymorphisms

NCI

Memory

Verbal Memory

Visual Memory

Processing Speed

Executive Function

Reaction Time

30 40 50 60 70 80 90 100 110 120

є3/є3 є2/є3є3/є4є4/є4

90.5

93

93.5

90

91

92

88

53.5

70

74

82.5

58.5

42.5

58.5

43

39.5

72

90

90

54

78

82

54

53

102

101

101

90.5

106

97.5

95

106

72

88

71

89 96

109.5

Average Standard Scores for cognitive functions in particular groups of ApoE gene polymorphisms.

78.5

88.5

6“…increasing emphasis on early intervention to prevent or postpone dementia…”***

makes CNS Vital Signs a VALUABLE TOOL for your PRACTICE!

…Study included 360 children and adolescents (277 boys, 83 girls) between 7 and 15 years of age who had been diagnosed with ADHD at the Department of Child and Adolescent Psychiatry using K-SADS-PL and DSM-IV

…Subjects were grouped according to ADHD subtypes as PI (n = 51), R (n = 65), and CB (n = 165). Seventy-nine healthy children were recruited into the study as the control group

...Findings revealed controls scored better than ADHD subjects and ADHD subjects scored better on MPH than with no drug

AD/HD Baseline: 16-Year-Old Female

AD/HD Post Medication: 16-Year-Old Female

Janie, a sixteen-year-old girl struggling in school was given CNS Vital Signs VS4 Clinical Battery and scored below average compared to her peers in 7 of 11 cognitive domains (pre-dose). Her lowest scores were in domains represented by venerable frontal lobe tests. After reviewing H&P, all test results, the PCS -pediatric symptom checklist & the Vanderbilt AD/HD rating scales; Janie was given a prescription medication. Four weeks later she was administered the test again after being on medication (post dose). The CNS Vital Signs report is available immediately after the testing session ends and provides utility as a tool for assessing academic and vocational accommodations, secondary gain, as well as measuring medication effect and helping clinicians tailor medications to achieve optimal clinical benefit.

Psychometric Measures for Treatment Response

Adapted From:Effect of Methylphenidate on Neurocognitive Test Battery;

Journal of Clinical Psychopharmacology;Volume 34, Number 4, August 2014

*** Attention-deficit/hyperactivity disorder (ADHD); Søren Dalsgaard; Eur Child Adolesc

Psychiatry (2013) 22 (Suppl 1):S43–S48

*** RESTRICTIVE (DSM-V): If criterion A1 (inattention) is met, but no more than two symptoms from criterion A2 (hyperactivity / impulsivity) have been present for the past 6 months.

PI R CB

Neurocognition Index 87.62 (14.66) 90.71 (11.77) 90.25 (11.14) 96.91 (10.87) <0.001* (PI=R=CB) < control 95.53 (11.96) 98.66 (11.62) 97.38 (10)Composite Memory 84.56 (21.86) 87.97 (19.5) 91.89 (20.92) 96.73 (18.82) 0.01 PI < control 81.27 (22.57) 85.59 (20.44) 85.9 (17.7)Psychomotor speed 92.96 (10.49) 94.12 (10.87) 93.63 (12.54) 99.77 (16.58) <0.001 (PI=R=CB) < control 98.88 (9.77) 99.8 (11.09) 99.73 (10.52)Reaction time 78.54 (21.63) 83.15 (18.42) 81.86 (16.49) 83.26 (28.57) 0.65* 88.25 (19.19) 89.88 (17.98) 86.43 (17.92) Complex attention 91.38 (24.6) 94.92 (16.81) 90.77 (18.41) 102.15 (12.45) <0.001* (PI=R=CB) < control 105.51 (16.27) 108.53 (17.14) 107.58 (12.63)Cognitive flexibility 90.84 (16.15) 93.32 (15.51) 91.15 (14.1) 102.82 (15.28) <0.001 (PI=R=CB) < control 104.77 (15.63) 108.42 (14.14 106.58 (13.74)

Symbol Digit Coding (Processing Speed Domain) Correct responses 41.24 (12.73) 41.82 (13.8) 40.23 (12.36) 48.18 (11.77) <0.001 (PI=R=CB) < control Errors 0.92 (1.18) 1.09 (1.26) 1 (2.28) 3.6 (5.53) <0.001* (PI=R=CB) < control

Shifting Attention Test (Executive Function Domain)Correct responses 34.44 (10.09) 35.43 (11.33) 34.07 (9.95) 42.23 (9.98) <0.001 (PI=R=CB) < control Errors 15.34 (7.83) 15.71 (9.41) 17.52 (8.02) 11.55 (6.06) <0.001* (PI=R=CB) > controlCorrect reaction time 1290.6 (133.52) 1224.91(236.4) 1233.39 (175) 1188.6 (222.75) 0.01* CB > control

CPT (Simple Attention Domain)CPT Correct 38.54 (2.61) 37.84 (5.25) 38.3 (2.71) 39.19 (1.14) <0.001* R > control Omission 1.46 (2.61) 1.61 (2.15) 1.7 (2.71) 0.81 (1.14) <0.001* CB > control Commission errors 3.42 (4.65) 11.59 (66.7) 3.99 (4.02) 1.71 (1.68) <0.001* R > control, CB > control Choice RT correct 506.84 (79.92) 490.2 (100.28) 515.36 (81.96) 470.5 (68.55) <0.001 PI < control

Baseline Measurements

ControlMean (SD) P

Pairwise Comparisons Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean (SD)

PI R CB

Comparisons of CNSVS Domain Scores Between the AD/HD Groups Before MPH Medication Administration Comparisons After MPH Administration

*The Welch ANOVA test was used for comparisons between diagnostic groups, and post hoc comparisons were performed with Tamhane’s T2 test. All other comparisons were performed with the ANOVA test, and post hoc tests were performed with the Tukey test.

Evaluate the neuropsychological characteristics of PI - predominantly inattentive, R –restrictive, and CB - combined (inattentive & hyperactive) AD/HD subtypes...

Case Examples: AD/HD, Medication Effects

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mTBI / Concussion Post Injury: 20-Year-Old Male

mTBI / Concussion 2nd Post Injury: 20-Year-Old Male

Following a collision in a club rugby match Paul, a 20-year-old college student, visited the ER complaining of a headache and nausea. Not having a cognitive baseline Paul was given CNS Vital Signs VS4 Clinical Battery (1st post injury). Compared to his peers he scored below average in 4 of 11 cognitive domains. His lowest scores were in domains represented by frontal lobe tests. After examining Paul, and reviewing the CT scan, symptom scale as well as the cognitive test results; Paul was started on a concussion management protocol. Two weeks later after he was symptom free, he was administered the test again (2nd post injury). The CNS Vital Signs session and longitudinal reports were available immediately after the testing session allowing the clinician to evaluate and manage Paul efficiently at the office visit. The CNS Vital Signs testing platform is designed to support TBI, mTBI and sports concussion guidelines.

Correlation to Imaging Markers

Examining Microstructural White Matter in Active-Duty Soldiers with a History of Mild Traumatic Brain Injury and Traumatic StressMethod: Seventy-four active-duty U.S. soldiers with PTS (n = 16) and PTS with co-morbid history of mTBI (PTS/mTBI; n = 28) were compared to a military control group (n = 30). Participants received a battery of neurocognitive and clinical symptom measures. The number of abnormal DTI (diffusion tensor imaging) values was determined (>2 SDs from the mean of the control group) for fractional anisotropy (FA) and mean diffusivity (MD), and then compared between groups…Results: The comorbid PTS/mTBI group had significantly greater traumatic stress, depression, anxiety, and post-concussive symptoms, and they performed worse on neurocognitive testing than those with PTS alone and controls. The groups differed greatly on several clinical variables, but contrary to what we hypothesized, they did not differ greatly on primary and exploratory analytic approaches of hetero-spatial whole brain DTI analyses.Conclusion: In conclusion, our findings do not provide strong evidence of compromised white matter integrity between our clinical groups compared to controls using several analytic approaches. In contrast, our groups were best categorized by robust differences in clinical symptoms and neurocognitive scores (i.e., CNS Vital Signs / TOMM). As such, our findings suggest that psychological health conditions rather than pathoanatomical changes may be contributing to symptoms presented by soldiers with comorbid PTS and mTBI.

*Comparing symptom severity, neurocognitive functioning, and self-report measures of the control subjects and the… PCS-PTSD group (green stars). The significance threshold (0.05) is visible as a thick horizontal line. Control subjects exhibited significantly better neurocognitive performance, less sleepiness and anxiety, and less combat exposure. PCS-PTSD subjects exhibited significantly worse neurocognitive performance and higher PCS symptom.

NCI

Zung Anxiety

Verbal Memory

Processing Speed

Executive Function

Epworth Sleep

Reaction Time

Complex Attention

Cognitive Flexibility

PCL5

NSI

Combat Exposure

Statistically Not Significant

Statistically Significant

Log (p value)

log (0.05)

-12

-10 -8 -6 -4 -2 0

*Adapted from: Human Brain Mapping 38:2843–2864 (2017); Compromised Hippocampus-Striatum Pathway as a Potential Imaging Biomarker of Mild-Traumatic Brain Injury and Posttraumatic Stress Disorder; Rangaprakash et al.

Adapted from: Dretsch, Michael N., Rael T. Lange, Jeffery S. Katz, Adam Goodman, Thomas A. Daniel, Gopikrishna Deshpande, Thomas S. Denney, Grant L. Iverson, and Jennifer L. Robinson. 2017. “Examining Microstructural White Matter in Active-Duty Soldiers with a History of Mild Traumatic Brain Injury and Traumatic Stress.” The Open Neuroimaging Journal

Post Concussion Syndrome - PTSD

Case Examples: Concussion, mTBI, PTSD

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Efficient Collection of MIPS Quality Measures!CNS Vital Signs Enabling MCI Guidelines

PRECISION MEDICINE in Your Practice

Key Points:

MCI is clinically important, but often not recognized… Since cognition is the most sensitive indicator of brain function, and is cost effectively assessed, this creates an enormous opportunity to improve neurologic care.

Annual cognitive health assessment for patients 65 years and older

Assessment and treatment of factors contributing to MCI

Use an objective measure of cognition Periodically and routinely assessing cognitive

health with a standardized measure is necessary… should be documented in medical records over time to allow change in cognition to be recognized and addressed early.

The purpose of assessing cognitive health is not limited to identifying disease. Cognitive impairment is a dominant comorbidity…

“MCI generally corresponds to the term “mild neurocognitive disorder” used in the DSM-5”

Adapted from: Norman L. Foster, Mark W. Bondi, Rohit Das, Mary Foss, Linda A. Hershey, Steve Koh, Rebecca Logan, Carol Poole, Joseph W. Shega, Ajay Sood, Niranjan Thothala, Meredith Wicklund, Melissa Yu, Amy Bennett, David Wang Neurology Oct 2019, 93 (16) 705-713

*

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“1 in 9 people aged 45 years and older are experiencing (SCD) Subjective Cognitive Decline”

# Source: Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs; Archives of Clinical Neuropsychology; Volume 21, Issue 7, October 2006, Pages 623–643

“In a survey of its members, AARP found that ‘staying mentally sharp’ was a top

concern of 87 percent of respondents…” ^

^ Cognitive Aging: Progress in Understanding and Opportunities for Action; Institute of Medicine

Let us help you see the EARLY SIGNS!

CNS Vital Signs Turns the Subjective into Objective Insight

CNS VS Composite Memory Norms

CDC and Alzheimer's Association; Healthy Brain Initiative; https://www.cdc.gov/aging/healthybrain/

#

Objective I Valid I Reliable I Efficient I Reimbursable I Secure

www.CNSVS.com888.750.6941

To learn more about the CNS VS Neurocognitive Testing Procedure

for clinicians or to REGISTER for a Free In Clinic Trial

go to CNS Vital Signs…

BEGIN TODAY!In-Clinic & Telehealth Remote Neurocognitive Testing Broad-Spectrum Objective and Scientifically Valid & Reliable Neurocognitive Testing e.g., correlated

to ApoE Polymorphisms Lifespan Norms Ages 8 - 90 Millisecond Precision, Autoscored Reports with Serial Tracking

Memory – Healthy Aging

– Supports the DSM‐5 Neurocognitive Disorder and MCI‐Dementia‐Alzheimer’s Guidelines for Cognitive Assessment.

TBI – mTBI - Concussion Multiple Sclerosis Medication Effects Epilepsy Parkinson's Chronic Pain – Fibro Fog Sleep

AD/HD Substance Use

Disorder Medication Effects Bipolar Schizophrenia Depression /

Anxiety PTSD Asperger's High Functioning

Autism Eating Disorders Mild Hepatic

Encephalopathy

Neuro Psych Other

Cancer Cognition –Chemo Brain

HIV / HAND Metabolic / Diabetes Cardiovascular Prion or Lyme Disease Cardiac Surgery Diet & Exercise Occupational Health Human Performance Forensic Neurotoxicity Genetic Phenotype

…in Neurodegenerative, Neuropsychiatric, Neurotraumatic and Neurodevelopmental Disorders CNS Vital Signs is Widely Used to Measure Neurocognition

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