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Do Now:• What is color blindness?
Homework due today
• Re-read pg. 377 to 381 stopping Genetic Control, complete the 10% as a group (each person will have their own sheet to complete.– For you to keep
• Completion of Genetics Worksheet• Also, read and take notes from pages 380-381. • Cell Specialization• “Dicer” enzyme (not in bold)• RNA Interference• Embryonic development • Differentiation
Homework due Friday
• Completion of Movie journal one • See handout• As a class we will begin to watch the movie Gattaca, it is
futuristic movie that deals with the topics of Eugenics and caste system (class).
• As the movie goes on you are expected to take short notes then the following day turn in a movie journal detail the previous day’s viewing.
• At the end of each class (last 10 minutes) you will be grouped to discuss what happened and why is it important. This is a chance for International students to ask questions of domestic students so that everyone has the same understanding. 12
Group Work • Get into the following pairings:• Sarah & Simon & Chris Nelson• Hannah & Dorje & Jim• Marcus & Bill & Joanna• Alex Wang & Tony Mao• Jason Zheng & Mike Vulpis• Henry & Sam Taylor• Re-read pg. 377 to 381 stopping Genetic
Control, complete the 10% as a group (each person will have their own sheet to complete)
Gene regulation - review• Single celled organism without a
nucleus are known as prokaryotes.• When they are replicating DNA, it only
uses the genes necessary for cell function rather than like humans where hundreds of cells are reproduced (replicated) but are never used.
• The organism has certain proteins that cause cells to replicate or regulate
Gene regulation• What is an operon?• These are involved in regulation. They
are cells with similar or connected functions.
• For example for a bacterium to utilize a sugar such as lactose (milk sugar) it would need operon to produce the proteins to allow it to be use absorb the lactose nutrients. The lac operon allows this to happen
Promoters & Operators• On one side of the regulatory region are
Promoters which is where RNA –polymerase binds to begin transcription.
• The other region is known as the Operator. This is where the binding of the lac operon proteins bind to the DNA.
• This is where the proteins can either block reproduction or allow it to proceed depending on the need of the organism.
Eukaryotic gene regulation• Transcription definition:• Transcription is the process by which the
information in a strand of DNA is copied into a new molecule of messenger RNA (mRNA). DNA safely and stably stores genetic material in the nuclei of cells as a reference, or template.
• When binding DNA sequences, regions of the cell will regulate the eukaryotic genes
Eukaryotic gene regulation• Transcription factors control the expression
of those genes. • Some factors promote or block expression
through RNA polymerase.• RNA polymerase - an enzyme that creates
or starts the formation of RNA from a DNA template during transcription. This is how cells reproduce.
Eukaryotic gene regulation• Promoters can activate binding sites for
transcription. Some factors can have major influences on what sites get activated (eventually expressed).
• Some factors need a chemical agent to become activated, like steroids.