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1 DNA Replication http://www.infection.bham.ac.uk/Teaching/minchin/jmol/Tutorials/DNA/DNA.html

DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

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Page 1: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

1

DNA Replication

http://www.infection.bham.ac.uk/Teaching/minchin/jmol/Tutorials/DNA/DNA.html

Page 2: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

2

Page 3: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

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Page 4: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

4

Page 5: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

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http://www.youtube.com/watch?v=teV62zrm2P0

Page 6: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

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http://www.youtube.com/watch?v=-mtLXpgjHL0&feature=related

http://www.youtube.com/watch?v=4jtmOZaIvS0&feature=related

Page 7: DNA Replication - University of Delaware › chem › bahnson › chem527 › DNA-replication.pdf · DNA template Primase RNA primer DNA polymerase Newly synthesized DNA . DnaB (helicase)

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Three-step pathway of nick sealing by DNA ligase.

Shuman S J. Biol. Chem. 2009;284:17365-17369

©2009 by American Society for Biochemistry and Molecular Biology