Diseases and Dependencies Alzheimer Disease

Parkinsons Disease

Drugs

Alcohol

Alzheimer Disease Plaque

Nerve tangles

Parkinson’s Disease Decrease CNS dopamine

secretion

General drug actions

Cocaine: stimulant

Cocaine

Coca Plant

Increases dopamine

Cocaine

Cocaine

What are the short-term effects of Cocaine Use?

•Increased energy •Decreased appetite •Mental alertness •Increased heart rate and blood pressure •Constricted blood vessels •Increased temperature •Dilated pupils

CocaineWhat are the long-term effects of Cocaine Use? Addiction Irritability and mood disturbances Restlessness Paranoia Auditory hallucinations Numerous effects on

HEART RESPIRATION

Examples of some drug opiates

Morphine

Heroine

Codeine

Heroine

Heroin is processed from morphine, a naturally occurring substance extracted from the seed pod of the Asian poppy plant.

Poppy Plant

Street names associated with heroin include "smack," "H," "skag," and "junk."

HeroineSoon after injection (or inhalation), heroin crosses the blood-brain barrier. In the brain, heroin is converted to morphine and binds rapidly to opioid receptors.

Methampethamines street names: Chalk, Crank, Croak,

Crypto, Crystal, Fire, Glass, Meth, Tweek , White Cross.

Methamphetamine can be taken orally, injected, snorted, or smoked.

Methampethamines

It rapidly enters the brain and causes a cascading release of norepinephrine and dopamine (and to a lesser extent, serotonin) resulting in euphoria and the availability of undirected energy.

LSD (lysergic acid diethylamide)

LSD: has a chemical structure that is very similar to the neurotransmitter called serotonin.

Originally from fungus of ryePlants: 1938

Cannabis

Tetrahydrocannabinol (THC) stimulates receptors of pain and appetite

Ectasy

Methylenedioxymethamphetamine (MDMA)Street Names: X, XTC, E, Adam, Lovers Speed, Eve, Beans, Clarity, Essence, etc.

Potential to damage the serotonin receptor sites as well as the serotonin neurons of the brain

Alcohol

Stimulates inhibitory receptors at high doses

Can be excitatory at low doses

Stimulant

Binds to acetylcholine receptors

Acetylcholine receptor