Jennifer Mielnicki Lewis

Director, Grants ManagementCalifornia Institute for Regenerative Medicine

December 21, 2020

1

2004$3B Bond funding -Proposition 71

1000+ProjectsFunded

68ClinicalTrials2700+

PatientsEnrolled

2

Current Research Budget Allocation

Program Allocation Remaining

CLIN Cure Sickle Cell $30M $17.4M

Progression Awards $1.84M $350,851

Total $31.84M $17.8M

*As of 11/30/2020, an additional $8.8M of the current research budget is uncommitted due to returned funds from the active portfolio

Additional Research Funds Requested for January to June 2021

Program Proposed Allocation Awards, Estimated

Clinical Unsolicited $100M 7 CLIN2s & 3 CLIN1s

Translation $60M 11

Quest $22M 15

Total $182M 36

Request for Board Action:

The CIRM team is requesting the ICOC to allocate additional $182M to support research programs planned for January – June 2021.