2003 Alkaloids

AlkaloidsU 0600 Dichloroketene—Chiral Olefin-Based Approach to Pyrrolizidines: Highly Stereo-

controlled Synthesis of (+)-Amphorogynine A (VIII). — A highly stereocontrolled approach to a new class of pyrrolizidines, based on diastereofacially selective [2 + 2] cycloaddition of dichloroketene with a chiral enol ether, [cf. cyclobutane (IV)] has been developed. — (ROCHE, C.; DELAIR*, P.; GREENE, A. E.; Org. Lett. 5 (2003) 10, 1741-1744; Lab. Etud. Dyn. Struct. Sel., CNRS, Univ. Joseph Fourier,F-38041 Grenoble, Fr.; Eng.) — Steudel

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