DETAILEDCURRICULUM of BachelorofScienceinChemistry · 2019-07-17 · its limitations. Packing of ions in crystals. Born-Landé equation with derivation and importance of Kapustinskii

DETAILED CURRICULUM

of

Bachelor of Science in Chemistry(B.Sc. Chemistry)

School of Science

Course Curriculum,B.Sc. ChemistrySchool of Science

2

FIRST YEAR

Semester - ISr. No. Course Code Course Title L T P C MarksCore Courses1. BSCM101 Inorganic Chemistry – I 4 0 2 6 1502. BSCM102 Physical Chemistry - I 4 0 2 6 150

Generic Elective (Any One)

3.BSPY103 Physics - I 4 0 2

6 150BSMA103 Mathematics - I 5 1 0BSBO103 Biomolecules 4 0 2

Ability Enhancement Compulsory Course4. BSEN101 Functional English - I 2 0 0 2 505. BSFC101 Foundation Course 0 1 1 2 50

TOTAL 22 550Total Marks for Practical is 50 out of 150 where ever applicable

Semester – IISr. No. Course Code Course Title L T P C MarksCore Courses1. BSCM201 Organic Chemistry – I 4 0 2 6 1502. BSCM202 Physical Chemistry - II 4 0 2 6 150Generic Elective (Any One)

3.BSPY203 Physics - II 4 0 2

6 150BSMA203 Mathematics - II 5 1 0BSBO203 Biotechnology and Human Welfare 4 0 2

Ability Enhancement Compulsory Course4. BSES201 Environmental Science 2 0 0 2 505. BSFC201 Foundation Course 0 1 1 2 50

22 550Total Marks for Practical is 50 out of 150 where ever applicable


3

SECOND YEAR

Semester – IIISr. No. Course Code Course Title L T P C MarksCore Courses1. BSCM301 Inorganic Chemistry - II 4 0 2 6 1502. BSCM302 Organic Chemistry - II 4 0 2 6 1503. BSCM303 Physical Chemistry – III 4 0 2 6 150Generic Elective (Any One)

3.BSPY304 Physics - III 4 0 2

6 150BSMA304 Mathematics - III 5 1 0BSBO304 IPR, Bioethics & Biosafety 4 0 2

Ability Enhancement Elective Course (Skill Based) (Any One)

4.BSCM305 Statistics - I 2 0 0

2 50BSCM306 Fuel Chemistry 2 0 0

Internship5. BSCM307 Internship 0 0 2 2 50


Semester – IVSr. No. Course Code Course Title L T P C MarksCore Courses1. BSCM401 Inorganic Chemistry – III 4 0 2 6 1502. BSCM402 Organic Chemistry – III 4 0 2 6 1503. BSCM403 Physical Chemistry – IV 4 0 2 6 150Generic Elective (Any One)

3.BSPY404 Physics – IV 4 0 2

6 150BSMA404 Mathematics - IV 5 1 0BSBO404 Enterpreneurship Development 4 0 2

Ability Enhancement Elective Course (Skill Based) (Any One)

4.BSCM405 Statistic – II 2 0 0

50BSCM406 Quantum Chemistry 2 0 0


TOTAL 28 700Total Marks for Practical is 50 out of 150 where ever applicable,


4

THIRD YEAR

Semester – VSr. No. Course Code Course Title L T P C MarksCore Courses1. BSCM501 Organic Chemistry – IV 4 0 2 6 1502. BSCM502 Physical Chemistry – V 4 0 2 6 150Discipline Specific Elective (Any Two)

3.BSCM503 Industrial Chemistry 4 0 2

6 150BSCM504 Green Chemistry 4 0 2

4.BSCM505 Polymer Chemistry 4 0 2

6 150BSCM506 Novel Inorganic Chemistry 4 0 2



Semester – VISr. No. Course Code Course Title L T P C MarksCore Courses1. BSCM601 Inorganic Chemistry – IV 4 0 2 6 1502. BSCM602 Organic Chemistry – V 4 0 2 6 150Discipline Specific Elective (Any Two)

3.BSCM603 Drug and Dyes 4 0 2

6 150BSCM604 Application of Computers 4 0 2

4.BSCM605 Analytical Chemistry 4 0 2

6 150BSCM606 Instrumental Chemistry 4 0 2



5

CORE COURSE (IN CHEMISTRY)

SEM-ICourse Title Inorganic Chemistry ICourse Code BSCM101Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives

Aim of the Course

This course explains the importance atomic theory and its role in developing the modelof the atom. It also discusses the origin of Schrodinger wave equation and itsapplication in calculating the energy and wave functions of various atomic andmolecular systems.It also involves periodicity of elements in addition to reflection ofchemical bonding concept.It also describes the redox reactions and its applications.

After completing this course student will be able to:1. Explain the importance of atomic theory in developing the model of the atom.2. Understand the origin of Schrodinger wave equation and its application in calculatingthe energy and wave functions of various atomic and molecular systems.3. Understand the concepts of periodic table,redox reactions and chemical bonding.

UNIT-I Atomic Structure:Bohr’s theory, its limitations and atomic spectrum of hydrogen atom. Wave mechanics:de Broglie equation, Heisenberg’s Uncertainty Principle and its significance,Schrödinger’s wave equation, significance of ψ and ψ2. Quantum numbers and theirsignificance. Normalized and orthogonal wave functions. Sign of wave functions. Radialand angular wave functions for hydrogen atom. Radial and angular distribution curves.Shapes of s, p, d and f orbitals. Contour boundary and probability diagrams.Pauli’s Exclusion Principle, Hund’s rule of maximum multiplicity, Aufbau’s principle andits limitations, Variation of orbital energy with atomic number. (14 Lectures)

Periodicity of Elements:s, p, d, f block elements, the long form of periodic table. Detailed discussion of thefollowing properties of the elements, with reference to s & p-block.(a) Effective nuclear charge, shielding or screening effect, Slater rules, variation ofeffective nuclear charge in periodic table.(b) Atomic radii (van der Waals)(c) Ionic and crystal radii.(d) Covalent radii (octahedral and tetrahedral)(e) Ionization enthalpy, Successive ionization enthalpies and factors affectingionization energy. Applications of ionization enthalpy.(f) Electron gain enthalpy, trends of electron gain enthalpy.(g) Electronegativity, Pauling’s/ Mulliken’s/ Allred Rachow’s/ and Mulliken-Jaffé’selectronegativity scales. Variation of electronegativity with bond order, partial charge,hybridization, group electronegativity. Sanderson’s electron density ratio.

(16 Lectures)

Oxidation-Reduction:Redox equations, Standard Electrode Potential and its application to inorganicreactions. Principles involved in volumetric analysis to be carried out in class. 4 lectures

UNIT-II

UNIT-III


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Chemical Bonding:(i) lonic bond: General characteristics, types of ions, size effects, radius ratio rule andits limitations. Packing of ions in crystals. Born-Landé equation with derivation andimportance of Kapustinskii expression for lattice energy. Madelung constant,Born-Haber cycle and its application, Solvation energy.(ii) Covalent bond: Lewis structure, Valence Bond theory (Heitler-London approach).Energetics of hybridization, equivalent and non-equivalent hybrid orbitals. Bent’s rule,Resonance and resonance energy, Molecular orbital theory. Molecular orbital diagramsof diatomic and simple polyatomic molecules N2, O2, C2, B2, F2, CO, NO, and their ions;HCl, BeF2, CO2, (idea of s-p mixing and orbital interaction to be given). Formal charge,Valence shell electron pair repulsion theory (VSEPR), shapes of simple molecules andions containing lone pairs and bond pairs of electrons, multiple bonding (σ and π bondapproach) and bond lengths.Covalent character in ionic compounds, polarizing power and polarizability. Fajan’srules and consequences of polarization. Ionic character in covalent compounds: Bondmoment and dipole moment. Percentage ionic character from dipole moment andelectronegativity difference.(iii) Metallic Bond: Qualitative idea of valence bond and band theories. Semiconductorsand insulators, defects in solids.(iv) Weak Chemical Forces: van der Waals forces, ion-dipole forces, dipole-dipoleinteractions, induced dipole interactions, Instantaneous dipole-induced dipoleinteractions. Repulsive forces, Hydrogen bonding (theories of hydrogen bonding,valence bond treatment) Effects of chemical force, melting and boiling points, solubilityenergetics of dissolution process. (26 Lectures)

UNIT-IV

Text and References Reference Books:1. Lee, J.D. Concise Inorganic Chemistry, ELBS, 1991.2. Douglas, B.E. and Mc Daniel, D.H., Concepts & Models of Inorganic Chemistry,Oxford, 19703.Atkins, P.W. & Paula, J. Physical Chemistry, Oxford Press, 2006.4. Day, M.C. and Selbin, J. Theoretical Inorganic Chemistry, ACS Publications 1962.

Course Title Physical Chemistry–ICourse Code BSCM102Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course describes the three states of matter are the three distinct physical forms

that matter can take in most environments: solid, liquid, and gas. It includes kinetictheory of gases, collision theory,behaviour of real gases,qualitative funda of liquids, Itfocuses on the importance of various fundamental concepts of physicalchemistry,Nature of the solid state, basics of symmetry, analysis by crystallographicmethods and Ionic Equilibrium.It deals with equilibrium reactions between ions inaqueous solution. It introduces the concept of pH and calculations related to it for acidsand bases.


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UNIT-I Gaseous state:Kinetic molecular model of a gas: postulates and derivation of the kinetic gas equation;collision frequency; collision diameter; mean free path and viscosity of gases, includingtheir temperature and pressure dependence, relation between mean free path andcoefficient of viscosity, calculation of σ from η ; variation of viscosity withtemperature and pressure.Maxwell distribution and its use in evaluating molecular velocities (average, root meansquare and most probable) and average kinetic energy, law of equipartition of energy,degrees of freedom and molecular basis of heat capacities.

Behaviour of real gases: Deviations from ideal gas behaviour, compressibility factor, Z,and its variation with pressure for different gases. Causes of deviation from idealbehaviour. vander Waals equation of state, its derivation and application in explainingreal gas behaviour, mention of other equations of state (Berthelot, Dietrici); virialequation of state; van der Waals equation expressed in virial form and calculation ofBoyle temperature. Isotherms of real gases and their comparison with van der Waalsisotherms, continuity of states, critical state, relation between critical constants andvan der Waals constants, law of corresponding states. (18 Lectures)

Liquid state:Qualitative treatment of the structure of the liquid state; Radial distribution function;physical properties of liquids; vapour pressure, surface tension and coefficient ofviscosity, and their determination. Effect of addition of various solutes on surfacetension and viscosity. Explanation of cleansing action of detergents. Temperaturevariation of viscosity of liquids and comparison with that of gases. Qualitativediscussion of structure of water.

(6 Lectures)

Solid state:Nature of the solid state, law of constancy of interfacial angles, law of rational indices,Miller indices, elementary ideas of symmetry, symmetry elements and symmetryoperations, qualitative idea of point and space groups, seven crystal systems andfourteen Bravais lattices; X-ray diffraction, Bragg’s law, a simple account of rotatingcrystal method and powder pattern method. Analysis of powder diffraction patterns ofNaCl, CsCl and KCl. Defects in crystals. Glasses and liquid crystals. (16 Lectures)

Ionic equilibria:Strong, moderate and weak electrolytes, degree of ionization, factors affecting degreeof ionization, ionization constant and ionic product of water. Ionization of weak acidsand bases, pH scale, common ion effect; dissociation constants of mono-, di-andtriprotic acids (exact treatment).Salt hydrolysis-calculation of hydrolysis constant, degree of hydrolysis and pH fordifferent salts. Buffer solutions; derivation of Henderson equation and its applications;buffer capacity, buffer range, buffer action and applications of buffers in analyticalchemistry and biochemical processes in the human body.Solubility and solubility product of sparingly soluble salts – applications of solubilityproduct principle. Qualitative treatment of acid – base titration curves (calculation ofpH at various stages). Theory of acid–base indicators; selection of indicators and theirlimitations. Multistage equilibria in polyelectrolyte systems; hydrolysis and hydrolysisconstants. (20 Lectures)

UNIT II:

UNIT-III:

UNIT-IV:


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Reference Books:

1. Ball, D. W. Physical Chemistry Thomson Press, India (2007).2. Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004).3. Mortimer, R. G. Physical Chemistry 3rd Ed. Elsevier: NOIDA, UP (2009).

Course Title Physics – ICourse Code BSPY103Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of physics up to 10+2 level.Course objectives The course is an introduction to Classical Mechanics, and is designed to impart basic

understanding of the laws of motion of objects and some material properties, withrelevant applications.

Unit-I

Unit-II

Unit-III

Unit-IV

Laws of Motion: Frames of reference. Newton’s Laws of motion. Dynamics of a systemof particles. Centre of Mass. Momentum and Energy: Conservation of momentum.Work and energy. Conservation of energy. Motion of rockets. Rotational Motion:Angular velocity and angular momentum. Torque. Conservation of angular momentum.Oscillations: Simple harmonic motion. Differential equation of SHM and its solutions.Kinetic and Potential Energy, Total Energy and their time averages. Damped oscillations.

Gravitation: Newton’s Law of Gravitation. Motion of a particle in a central force field(motion is in a plane, angular momentum is conserved, areal velocity is constant).Kepler’s Laws (statements only). Satellite in circular orbit and applications.Geosynchronous orbits. Basic idea of global positioning system (GPS). Weightlessness.Physiological effects on astronauts.

Elasticity of materials: Hooke’s law - Stress-strain diagram - Elastic moduli-Relationbetween elastic constants - Poisson’s Ratio-Expression for Poisson’s ratio in terms ofelastic constants - Work done in stretching and work done in twisting a wire - Twistingcouple on a cylinder - Determination of Rigidity modulus by static torsion - Torsionalpendulum - Determination of Rigidity modulus and moment of inertia - q, η and σ bySearle's method.

Speed Theory of Relativity: Constancy of the speed of light. Postulates of SpecialTheory of Relativity. Length contraction. Time dilation. Relativistic addition of velocities.

Text and References Reference Books:1.University Physics. F.W. Sears, M.W. Zemansky and H.D. Young, 13/e, 1986,Addison-Wesley.2.Mechanics Berkeley Physics, v.1: Charles Kittel, et. al. 2007, Tata McGraw-Hill.3. Physics – Resnick, Halliday & Walker 9/e, 2010, Wiley.4. University Physics, Ronald Lane Reese, 2003, Thomson Brooks/Cole


9

Course Title Mathematics-ICourse Code BSMA103Course Credits L T P Credits

5 1 0 6Prerequisites Students should have basic knowledge of maths up to 10+2 level.Course objectives This course describes the basics of mathematics that involves Trigonometry and its

identities,the concept and utilization of differentiation and integration,introduction ofmatrices.

Unit-I

Unit-II

Unit-III

Unit-IV

Trigonometry and its identities, inverse trigonometric functions, Concept of a limit andfunctions, Continuity and derivative of elementary functions, Rules of differentiation(without proof), Chain rule (without proof), differentiation of implicit functions,Indeterminate forms, L.Hospital’s rules, Applications of Derivatives: maxima andminima of function. (15 Lectures)

Standard integration formulae, Integration by the method of substitution, Integrationby parts, Integration by the method of partial fractions, definite integration,fundamental theorem of calculus Applications of Integrations: Area and volume

(15 Lectures)

Introduction to matrices, different types of matrices, Elementary operations onmatrices and types of matrices, Symmetric and skew-symmetric matrices, Hermitianand skew – Hermitian matrices. Rank of a matrix. Row Reduced Echelon form of amatrix and matrix inversion using it. (15 Lectures)

Homogeneous and Non-homogeneous linear equations. Application of matrices insolving a system of simultaneous linear equations. Eigen values, Eigen vectors and thecharacteristic equation of a matrix. Cayley Hamilton theorem (without proof) and itsuse in finding inverse of a matrix. (15 Lectures)

Text and References Reference Books:1. Shanti Narayan, Integral Calculus, S. Chand & Co. Ltd, 1999.2. V. M. Shah, Introductory Calculus, Acharya Book Depot,1980.3. Erwin Kreyszig, Advanced Engineering Mathematics, John Wiley and Sons Inc, 1983.4. G. B. Thomas Jr. and R. L. Finney, Calculus and Analytic Geometry, Addison-WesleyPublishers, 1999. 8. David V. Widder, Advanced Calculus, Prentice-Hall of India, 1989.5. T. M. Apostol, Calculus, Volumes 2, Wiley Eastern. 6. Linear Algebra and itsApplications, David C. Lay, Pearson Education.

Course Title BiomoleculesCourse Code BSBO103Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of biology up to 10+2 level.Course objectives This course introduces large macromolecules such as Carbohydrates,Proteins,Lipids,Nucleic

acids,Enzymes involving the introduction, biological functions,purification and their reactivityto get general information in terms of biochemistry.


10

Unit-I

Unit-II

Unit-III

Unit-IV

Carbohydrates: Structure, Function and properties of Monosaccharides, Disaccharides andPolysaccharides. Homo & Hetero Polysaccharides, Mucopolysaccharides, Bacterial cell wallpolysaccharides,Glycoproteins and their biological functions . (10 lectures)

Proteins: Structure & Function. Structure and properties of Amino acids, Types of proteins andtheir classification, Forces stabilizing protein structure and shape. Different Level of structuralorganization of proteins, Protein Purification. Denaturation and renaturation of proteins.Fibrous and globular proteins. (10 lectures)

Lipids: Structure and functions –Classification, nomenclature and properties of fatty acids,essential fatty acids. Phospholipids, sphingolipids, glycolipids, cerebrosides, gangliosides,Prostaglandins, Cholesterol.

Nucleic acids: Structure and functions: Physical & chemical properties of Nucleic acids,Nucleosides & Nucleotides, purines & pyrimidines, Biologically important nucleotides, Doublehelical model of DNA structure and forces responsible for A, B & Z – DNA, denaturation andrenaturation of DNA. (20 lectures)

Enzymes: Nomenclature and classification of Enzymes, Holoenzyme, apoenzyme, Cofactors,coenzyme, prosthetic groups, metalloenzymes, monomeric & oligomeric enzymes, activationenergy and transition state, enzyme activity, specific activity, common features of active sites,enzyme specificity: types & theories, Biocatalysts from extreme thermophilic andhyperthermophilic archaea and bacteria. Role of: NAD+, NADP+, FMN/FAD, coenzymes A,Thiamine pyrophosphate, Pyridoxal phosphate, lipoic-acid, Biotin vitamin B12,Tetrahydrofolate and metallic ions. (20 lectures)

Text and References REFERENCE BOOKS:

1.Berg, J. M., Tymoczko, J. L. and Stryer, L. (2006). Biochemistry. VI Edition. W.H Freeman andCo.2.Buchanan, B., Gruissem, W. and Jones, R. (2000) Biochemistry and Molecular Biology ofPlants.American Society of Plant Biologists.3.Nelson, D.L., Cox, M.M. (2004) Lehninger Principles of Biochemistry, 4th Edition, WHFreeman and Company, New York, USA.4.Hopkins, W.G. and Huner, P.A. (2008) Introduction to Plant Physiology. John Wiley andSons.5. Salisbury, F.B. and Ross, C.W. (1991) Plant Physiology, Wadsworth Publishing Co. Ltd.


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Course Title Functional English – ICourse Code BSEN101Course Credits L T P Credits

2 0 2Prerequisites Students should have basic knowledge of English up to 10+2 level.Course objectives Students should get the basic knowledge of Grammar

Unit-I

Unit-II

Unit-III

Unit-IV

BasicsArticles, Prepositions, Degrees of comparison, Tenses; Kinds and Uses, Active and PassiveVoice, Phrases Clauses and Sentences, Kinds of sentences, Reported Speech. (12 Lectures)

Basic CompositionParagraph Writing, Business Correspondence, Official Reports (07 Lectures)

Basic PhoneticsThe Production of Speech, The Sounds of English, Phonetic Transcription, Syllable and Stress,Intonation (08 Lectures)

Basic ConversationEnglish in use, English for routine communicative functions, Speech practice (03 Lectures)

Text and References Reference Books:

1.Murphy R., Intermediate English Grammar: Reference and Practice for South Asian Students,Cambridge University Press, 2001.2. Thaker P.K., Desai S. and Purani T.J. (eds), Developing English Skills : A Composite Course forIntermediate Students, Oxford University Press, 1997.3.Mohan K. and Banerji M., Developing Communication Skills, Mc.Millan Co. Publication 1990.4. Krishnaswami N and Sriram T., Creative English for Communication, Mc.MillanCo.Publication 1992.5. Board of Editors,Written and Spoken Communication in English, University Press PrivateLimited,


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SEM-IICourse Title Organic Chemistry-ICourse Code BSCM201Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of organic chemistry up to 10+2 level.Course objectives This course in consideration to Basics of Organic Chemistry,Electronic Displacements,

fission by homolytic and heterolytic pathway,type of organic reactions,aspects ofstereochemistry, Chemistry of Aliphatic Hydrocarbons.It enhances the idea aboutproperty of conjugated cycloalkenes.

Unit-I

Unit-II

Unit-III

Basics of Organic ChemistryOrganic Compounds: Classification, and Nomenclature, Hybridization, Shapes ofmolecules, Influence of hybridization on bond properties.Electronic Displacements: Inductive, electromeric, resonance and mesomeric effects,hyperconjugation and their applications; Dipole moment; Organic acids and bases; theirrelative strength.Homolytic and Heterolytic fission with suitable examples. Curly arrow rules, formalcharges; Electrophiles and Nucleophiles; Nucleophlicity and basicity; Types, shape andtheir relative stability of Carbocations, Carbanions, Free radicals and Carbenes.Introduction to types of organic reactions and their mechanism: Addition, Eliminationand Substitution reactions. (6 Lectures)

Stereochemistry:Fischer Projection, Newmann and Sawhorse Projection formulae and theirinterconversions; Geometrical isomerism: cis–trans and, syn-anti isomerism E/Znotations with C.I.P rules.Optical Isomerism: Optical Activity, Specific Rotation, Chirality/Asymmetry,Enantiomers, Molecules with two or more chiral-centres, Distereoisomers, mesostructures, Racemic mixture and resolution. Relative and absolute configuration: D/Land R/S designations. (18 Lectures)

Chemistry of Aliphatic HydrocarbonsA. Carbon-Carbon sigma bondsChemistry of alkanes: Formation of alkanes, Wurtz Reaction, Wurtz-Fittig Reactions,Free radical substitutions: Halogenation -relative reactivity and selectivity.Reactions of alkenes: Electrophilic additions their mechanisms (Markownikoff/ AntiMarkownikoff addition), mechanism of oxymercuration-demercuration,hydroboration-oxidation, ozonolysis, reduction (catalytic and chemical), syn andanti-hydroxylation (oxidation). 1,2-and 1,4-addition reactions in conjugated dienes and,Diels-Alder reaction; Allylic and benzylic bromination and mechanism, e.g. propene,1-butene, toluene, ethyl benzene.Reactions of alkynes: Acidity, Electrophilic and Nucleophilic additions. Hydration toform carbonyl compounds, Alkylation of terminal alkynes.

B. Carbon-Carbon pi bonds:Formation of alkenes and alkynes by elimination reactions, Mechanism of E1, E2, E1cbreactions. Saytzeff and Hofmann eliminations.

C. Cycloalkanes and Conformational AnalysisTypes of cycloalkanes and their relative stability, Baeyer strain theory, Conformationanalysis of alkanes: Relative stability: Energy diagrams of cyclohexane: Chair, Boat andTwist boat forms; Relative stability with energy diagrams. (24 Lectures)


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Unit-IVAromatic HydrocarbonsAromaticity: Hückel’s rule, aromatic character of arenes, cyclic carbocations/carbanionsand heterocyclic compounds with suitable examples. Electrophilic aromaticsubstitution: halogenation, nitration, sulphonation and Friedel-Craft’salkylation/acylation with their mechanism. Directing effects of the groups.(12 Lectures)


1.Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (PearsonEducation).2. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry ofNatural Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).3. Eliel, E. L. & Wilen, S. H. Stereochemistry of Organic Compounds; Wiley: London,1994.4. Kalsi, P. S. Stereochemistry Conformation and Mechanism; New Age International,2005.

Course Title Physical Chemistry -IICourse Code BSCM202Course Credits L T P Credits

4 0 2 6Course objectives This course describes the concept of thermodynamics by different proposed laws, free

energy functions, Systems of Variable Composition, Criteria of thermodynamicequilibrium, degree of advancement of reaction, chemical equilibria in ideal gases,concept of fugacity. The information about the property of a solvent that dependsupon the total number of solute particles present in a solution is involved.

Unit-I

Unit-II

Chemical ThermodynamicsIntensive and extensive variables; state and path functions; isolated, closed and opensystems; zeroth law of thermodynamics.First law: Concept of heat, q, work, w, internal energy, U, and statement of first law;enthalpy, H, relation between heat capacities, calculations of q, w, U and H forreversible, irreversible and free expansion of gases (ideal and van der Waals) underisothermal and adiabatic conditions.

Thermochemistry: Heats of reactions: standard states; enthalpy of formation ofmolecules and ions and enthalpy of combustion and its applications; calculation ofbond energy, bond dissociation energy and resonance energy from thermochemicaldata, effect of temperature (Kirchhoff’s equations) and pressure on enthalpy ofreactions. Adiabatic flame temperature, explosion temperature.

Second Law: Concept of entropy; thermodynamic scale of temperature, statement ofthe second law of thermodynamics; molecular and statistical interpretation of entropy.Calculation of entropy change for reversible and irreversible processes.

Third Law: Statement of third law, concept of residual entropy, calculation of absoluteentropy of molecules.

Free Energy Functions: Gibbs and Helmholtz energy; variation of S, G, A with T, V, P;Free energy change and spontaneity. Relation between Joule-Thomson coefficient andother thermodynamic parameters; inversion temperature; Gibbs-Helmholtz equation;Maxwell relations; thermodynamic equation of state. (36 Lectures)

Systems of Variable Composition:Partial molar quantities, dependence of thermodynamic parameters on composition;Gibbs-Duhem equation, chemical potential of ideal mixtures, change in thermodynamicfunctions in mixing of ideal gases. (8 Lectures)


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Unit-III

Unit-IV

Chemical Equilibrium:Criteria of thermodynamic equilibrium, degree of advancement of reaction, chemicalequilibria in ideal gases, concept of fugacity. Thermodynamic derivation of relationbetween Gibbs free energy of reaction and reaction quotient. Coupling of exoergic andendoergic reactions. Equilibrium constants and their quantitative dependence ontemperature, pressure and concentration. Free energy of mixing and spontaneity;thermodynamic derivation of relations between the various equilibrium constants Kp ,Kc and Kx. Le Chatelier principle (quantitative treatment); equilibrium between idealgases and a pure condensed phase. (8 Lectures)

Solutions and Colligative Properties:Dilute solutions; lowering of vapour pressure, Raoult’s and Henry’s Laws and theirapplications. Excess thermodynamic functions.Thermodynamic derivation using chemical potential to derive relations between thefour colligative properties(i) relative lowering of vapour pressure, (ii) elevation of boiling point,(iii) Depression of freezing point, (iv) osmotic pressure] and amount of solute.

Applications in calculating molar masses of normal, dissociated and associated solutesin solution. (8 Lectures)


1. Peter, A. & Paula, J. de. Physical Chemistry 9th Ed., Oxford University Press (2011).2. Castellan, G. W. Physical Chemistry 4th Ed., Narosa (2004).3. Engel, T. & Reid, P. Physical Chemistry 3rd Ed., Prentice-Hall (2012).4. McQuarrie, D. A. & Simon, J. D. Molecular Thermodynamics Viva Books Pvt. Ltd.: New

Delhi (2004).5. Assael, M. J.; Goodwin, A. R. H.; Stamatoudis, M.; Wakeham, W. A. & Will, S.

Commonly Asked Questions in Thermodynamics. CRC Press: NY (2011).6. Levine, I .N. Physical Chemistry 6th Ed., Tata Mc Graw Hill (2010).7. Metz, C.R. 2000 solved problems in chemistry, Schaum Series (2006)

Course Title Physics – II

Course Code BSPY203Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of physics up to 10+2 levelCourse objectives The course is an introduction to Electricity and Magnetism, and is designed to impart

basic understanding of the related laws and material properties. Course also includeselementary introduction of electromagnetic radiation.

Unit-I

Unit-II

Vector Analysis: Scalar and Vector product, gradient, divergence, Curl and theirsignificance, Vector Integration, Line, surface and volume integrals of Vector fields,Gauss-divergence theorem and Stoke's theorem of vectors (statement only).

Electrostatics: Electrostatic Field, electric flux, Gauss's theorem of electrostatics.Applications of Gauss theorem- Electric field due to a point charge, infinite line ofcharge, uniformly charged spherical shell and solid sphere, plane charged sheet,charged conductor. Electric potential as line integral of electric field, potential due to apoint charge, electric dipole, uniformly charged spherical shell and solid sphere.Calculation of electric field from potential. Capacitance of an isolated sphericalconductor. Parallel-plate, spherical and cylindrical condenser. Energy per unit volume in


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Unit-III

Unit-IV

electrostatic field. Dielectric medium, Polarisation, Displacement vector. Gauss'stheorem in dielectrics. Parallel-plate capacitor completely filled with dielectric.

Magnetostatics: Biot-Savart's law and its applications- straight conductor, circular coil,solenoid carrying current. Divergence and curl of magnetic field. Magnetic vectorpotential. Ampere's circuital law. Magnetic properties of materials: Magnetic intensity,magnetic induction, permeability, magnetic susceptibility. Brief introduction of dia-,para- and ferromagnetic materials. Electromagnetic Induction: Faraday's laws ofelectromagnetic induction, Lenz's law, self and mutual inductance, L of single coil, M oftwo coils. Energy stored in magnetic field.

Maxwell's equations and Electromagnetic wave propagation: Equation of continuity ofcurrent, Displacement current, Maxwell's equations, Poynting vector, energy density inelectromagnetic field, electromagnetic wave propagation through vacuum and isotropicdielectric medium, transverse nature of EM waves, polarization.

Text and References Reference Books

1. Electricity and Magnetism, E. M. Purcell, 1986, McGraw-Hill Education.2. Electricity & Magnetism, J. H. Fewkes & J. Yarwood. Vol. I, 1991, Oxford UniversityPress.3. Electricity and Magnetism, D. C. Tayal, 1988, Himalaya Publishing House.4. University Physics, Ronald Lane Reese, 2003, Thomson Brooks/Cole.5. Introduction to Electrodynamics, D. J. Griffiths, 3rd Edn, 1998, Benjamin Cummings

Course Title Mathematics-II ( Ordinary Differential Equations and Partial Differentiation )Course Code BSMA203Course Credits L T P Credits

5 1 0 6Prerequisites Students should have basic knowledge of maths up to 10+2 level.Course objectives This course reflects the ordinary differential equation, Equations in which variables are

separable, Exact differential equations, Linear differential equations, applications ofCardiography (ECG) and Partial Derivatives in detail.

Unit-I

Unit-II

Unit-III

Unit-IV

Unit-V

Ordinary Differential Equations, Degree and order of a differential equation, Equationsof first order and first degree, Equations in which variables are separable,Homogeneous equations, Linear equations and equations reducible to the linear form.

(12 Lectures)

Exact differential equations, Integrating factors. Applications of first order equations:Mixture problem, Orthogonal trajectories, Decay and Growth problems, Temperatureproblem. (12 Lectures)

Linear differential equations of higher order, Homogeneous equations, Differentialoperators, Method of solving homogeneous equations, Non-homogeneous equations,Inverse operators, Methods of solving non-homogeneous equations. ApplicationCardiography (ECG). (12 Lectures)

Function of several variables, Limit and continuity of function of several variables,partial derivatives of function of two variables, Total differential, Chain rule, implicitdifferentiation, Euler’s theorem for homogeneous function. (12 Lectures)

Applications of Partial Derivatives, Tangent plane, Normal line, Linear approximation,Maximum and minimum values by second derivative test, Lagrange’s method ofmultipliers, Taylor’s formula for two variables. (12 Lectures)


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Text and References Reference Books:1. Shanti Narayan, Integral Calculus, S. Chand & Co. Ltd, 1999.2. V. M. Shah, Introductory Calculus, Acharya Book Depot,1980.3. Erwin Kreyszig, Advanced Engineering Mathematics, John Wiley and Sons Inc, 1983.4. G. B. Thomas Jr. and R. L. Finney, Calculus and Analytic Geometry, Addison-WesleyPublishers, 1999. 8. David V. Widder, Advanced Calculus, Prentice-Hall of India, 1989.5. T. M. Apostol, Calculus, Volumes 2, Wiley Eastern. 6. Linear Algebra and itsApplications, David C. Lay, Pearson Education.

Course Title BIOTECHNOLOGY AND HUMAN WELFARE

Course Code BSBO203Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of biology up to 10+2 level.Course objectives This course describes industrial analysis of boimolecules ,art of cultivating plants and

live stock,study of science which applies on the criminal side-during criminalinvestigation as governed by the leagel standards of admissible evedence and criminalprocedure.It also states the health science.

Unit- I

Unit- II

Unit- III

Unit- IV

Unit-V

Industry: protein engineering; enzyme and polysaccharide synthesis, activity andsecretion, alcohol and antibiotic formation. (10Lectures)

Agriculture: N2 fixation: transfer of pest resistance genes to plants; interactionbetween plants and microbes; qualitative improvement of livestock. (10Lectures)

Environments: e.g. chlorinated and non-chlorinated organ pollutant degradation;degradation of hydrocarbons and agricultural wastes, stress management,development of biodegradable polymers such as PHB. (15Lectures)

Forensic science: e.g. solving violent crimes such as murder and rape; solving claims ofpaternity and theft etc. using various methods of DNA finger printing (12Lectures)

Health: e.g. development of non-toxic therapeutic agents, recombinant livevaccines, gene therapy, diagnostics, monoclonal in E.coli, human genome project.

(13Lecture)


1. Sateesh MK (2010) Bioethics and Biosafety, I. K. International Pvt Ltd.2. Sree Krishna V (2007) Bioethics and Biosafety in Biotechnology, New ageinternational publishers

Course Title Environmental Studies

Course Code BSES201Course Credits L T P Credits

2 0 0 2Prerequisites Students should have basic knowledge of environmental science up to 10+2 level.Course objectives This course appeals introduction of the branch of biology that deals with the relations

of organisms to one another and to their physical surroundings through ecofriendlysystem. It consists the introduction and classification of air pollutants and their effects,Characteristics and biochemical effects of some important water pollutants and itscontrol, solid and hazardous waste : treatment for the kinds of pollution.


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Unit-I

Unit-II

Unit-III

Unit-IV

Introduction of Environment, Ecology and EcosystemsEcology-Objectives and Classification Concepts of an ecosystem-structure & function ofecosystem components of ecosystem,Hydrological cycle, carbon cycle,oxygen cycle, Nitrogen cycle, Sulphur cycle, EcologicalPyramids major ecosystems:Forest Ecosystem, Grassland Ecosystem, Desert Ecosystem,Aquatic ecosystem, Estuarine Ecosystem. (8 Lectures)

Air pollution and its controlIntroduction, Classification of air pollutants, air pollutants and their effects, acid rain,photochemical smog, particulates.Characteristics and biochemical effects of someimportant air pollutants, Effect of air pollutants on man and environment, Air qualitystandard, air monitoring and control of air pollution. (7 Lectures)

Water pollution and its controlIntroduction, Classification of water pollutants, physical, chemical and biologicalcharacteristics of waste water, waste water treatment: Primary treatment-Sedimentation, coagulation, equalization, neutralization, secondary treatment-aerobictreatment-aerated lagoons, trickling filter, activated sludge process, oxidation ditchprocess, oxidation pond, anaerobic treatment-anaerobic sludge digestion, sludgetreatment and disposal and tertiary treatment-evaporation, ion exchange, adsorption,chemical precipitation, Electrodialysis, reverse osmosis. (8 Lectures)

Solid and hazardous waste: pollution, treatment and disposalIntroduction, Classification and origin, characteristics of solid wastes, objectives andconsiderations in solid waste management, methods of solid waste treatment anddisposal - composting, land filling, thermal processes-incineration, pyrolysis, recyclingand reuse of solid waste-co-disposal, bioconversion. (7 Lectures)

Text and References REFERENCE BOOKS:

1. Bharucha E., Textbook of Environmental Studies, UGC universities Press 2005.2. Mishra, D.D., Fundamental concepts in Environmental Studies, S.Chand & Co Ltd.20103. R. Rajagopalan, Environmental Studies, Oxford University Press.

SEM-IIICourse Title Inorganic Chemistry – IICourse Code BSCM301Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives It explains the importance of general principle of metallurgy imparting Chief modes of

occurrence of metals based on standard electrode potentials,theory proposed to defineacid base.It also gives the information about chemistry of s and p-block elements,studyand behaviour of noble gases . It also discusses the type and applications of inorganicpolymer.

Unit-I

Unit-II

General Principles of MetallurgyChief modes of occurrence of metals based on standard electrode potentials. Ellinghamdiagrams for reduction of metal oxides using carbon and carbon monoxide as reducingagent. Electrolytic Reduction, Hydrometallurgy. Methods of purification of metals:Electrolytic Kroll process, Parting process, van Arkel-de Boer process and Mond’sprocess, Zone refining. (6 Lectures)

Acids and BasesBrönsted-Lowry concept of acid-base reactions, solvated proton, relative strength of


18

Unit-III

Unit-IV

Unit-V

acids, types of acid-base reactions, levelling solvents, Lewis acid-base concept,Classification of Lewis acids, Hard and Soft Acids and Bases (HSAB) Application of HSABprinciple. (8 Lectures)

Chemistry of s and p Block Elements:Inert pair effect, Relative stability of different oxidation states, diagonal relationshipand anomalous behaviour of first member of each group. Allotropy and catenation.Complex formation tendency of s and p block elements.Hydrides and their classification ionic, covalent and interstitial. Basic beryllium acetateand nitrate.Study of the following compounds with emphasis on structure, bonding, preparation,properties and uses.Boric acid and borates, boron nitrides, borohydrides (diborane) carboranes andgraphitic compounds, silanes, Oxides and oxoacids of nitrogen, Phosphorus andchlorine. Peroxo acids of sulphur, interhalogen compounds, polyhalide ions,pseudohalogens and basic properties of halogens. (30 Lectures)

Noble Gases:Occurrence and uses, rationalization of inertness of noble gases, Clathrates;preparation and properties of XeF2, XeF4 and XeF6; Nature of bonding in noble gascompounds (Valence bond treatment and MO treatment for XeF2). Molecular shapesof noble gas compounds (VSEPR theory). (8 Lectures)

Inorganic Polymers:Types of inorganic polymers, comparison with organic polymers, synthesis, structuralaspects and applications of silicones and siloxanes. Borazines, silicates andphosphazenes, and polysulphates. (8 Lectures)

Text and References Reference Books:1.Lee, J.D. Concise Inorganic Chemistry, ELBS, 1991.2.Douglas, B.E; Mc Daniel, D.H. & Alexander, J.J. Concepts & Models of InorganicChemistry 3rd Ed., John Wiley Sons, N.Y. 1994.3.Greenwood, N.N. & Earnshaw. Chemistry of the Elements, Butterworth-Heinemann.1997.4.Cotton, F.A. & Wilkinson, G. Advanced Inorganic Chemistry, Wiley, VCH, 1999.5. Miessler, G. L. & Donald, A. Tarr. Inorganic Chemistry 4th Ed., Pearson, 2010.6. Shriver & Atkins, Inorganic Chemistry 5th Ed.

Course Title Organic Chemistry – IICourse Code BSCM302Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course explores the importance of chemistry of halogenated hydrocarbons,

preparation, properties and reactivity of alcohols, phenols, ethers, epoxides, study ofcarboxylic acid and their derivatives. It also in consideration of preparation, reactivityand applications of sulphur containing compounds.


19

Unit-I

Unit- II

Unit- III

Unit-IV

Unit-V

Chemistry of Halogenated Hydrocarbons:Alkyl halides: Methods of preparation, nucleophilic substitution reactions – SN1, SN2and SNi mechanisms with stereochemical aspects and effect of solvent etc.; nucleophilicsubstitution vs. elimination.Aryl halides: Preparation, including preparation from diazonium salts. nucleophilicaromatic substitution; SNAr, Benzyne mechanism.Relative reactivity of alkyl, allyl/benzyl, vinyl and aryl halides towards nucleophilicsubstitution reactions.Organometallic compounds of Mg and Li – Use in synthesis of organic compounds.

(16 Lectures)

Alcohols, Phenols, Ethers and EpoxidesAlcohols: preparation, properties and relative reactivity of 1°, 2°, 3° alcohols,Bouvaelt-BlancReduction; Preparation and properties of glycols: Oxidation by periodicacid and lead tetraacetate, Pinacol-Pinacolone rearrangement;Phenols: Preparation and properties; Acidity and factors effecting it, Ring substitutionreactions, Reimer–Tiemann and Kolbe’s–Schmidt Reactions, Fries and Claisenrearrangements with mechanism; Ethers and Epoxides: Preparation and reactions withacids. Reactions of epoxides with alcohols, ammonia derivatives and LiAlH4

(16 Lectures)

Carbonyl Compounds:Structure, reactivity and preparation; Nucleophilic additions, Nucleophilicaddition-elimination reactions with ammonia derivatives with mechanism; Mechanismsof Aldol and Benzoin condensation, Knoevenagel condensation, Claisan-Schmidt,Perkin, Cannizzaro and Wittig reaction, Beckmann and Benzil-Benzilic acidrearrangements, haloform reaction and Baeyer Villiger oxidation, α - substitutionreactions, oxidations and reductions (Clemmensen, Wolff-Kishner, LiAlH4, NaBH4, MPV,PDC and PGC);Addition reactions of unsaturated carbonyl compounds: Michael addition.Activemethylene compounds: Keto-enol tautomerism. Preparation and synthetic applicationsof diethyl malonate and ethyl acetoacetate. (14 Lectures)

Carboxylic Acids and their DerivativesPreparation, physical properties and reactions of monocarboxylic acids: Typicalreactions of Dicarboxylic acids, hydroxy acids and unsaturated acids: succinic/phthalic,lactic, malic, tartaric, citric, maleic and fumaric acidsPreparation and reactions of acid chlorides, anhydrides, esters and amides;Comparative study of nucleophilic sustitution at acyl group -Mechanism of acidic andalkaline hydrolysis of esters, Claisen condensation, Dieckmann and Reformatskyreactions, Hofmann-bromamide degradation and Curtius rearrangement.

(10 Lectures)

Sulphur containing compounds:Preparation and reactions of thiols, thioethers and sulphonic acids. (4 Lectures)

Text and References Reference Books

1.Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.(Pearson Education).2.Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (PearsonEducation).3. Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.


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Course Title PHYSICAL CHEMISTRY-III

Course Code BSCM303Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course describes the concept of phase euilibria, understanding the rates of

chemical reactions through chemical kinetics, the acceleration of a chemical reaction bya catalysis, study of physical and chemical phenomena that occur at the interface oftwo phases,kins of surface physics is concern.

Unit-I

Unit-II

Unit-III

Unit-IV

Phase Equilibria:Concept of phases, components and degrees of freedom, derivation of Gibbs PhaseRule for nonreactive and reactive systems; Clausius-Clapeyron equation and itsapplications to solid-liquid, liquid-vapour and solid-vapour equilibria, phase diagram forone component systems, with applications.Phase diagrams for systems of solid-liquid equilibria involving eutectic, congruent andincongruent melting points, solid solutions.Three component systems, water-chloroform-acetic acid system, triangular plots.Binary solutions: Gibbs-Duhem-Margules equation, its derivation and applications tofractional distillation of binary miscible liquids (ideal and nonideal), azeotropes, leverrule, partial miscibility of liquids, CST, miscible pairs, steam distillation.Nernst distribution law: its derivation and applications. (28 Lectures)

Chemical KineticsOrder and molecularity of a reaction, rate laws in terms of the advancement of areaction, differential and integrated form of rate expressions up to second orderreactions, experimental methods of the determination of rate laws, kinetics of complexreactions (integrated rate expressions up to first order only): (i) Opposing reactions (ii)parallel reactions and (iii) consecutive reactions and their differential rate equations(steady-state approximation in reaction mechanisms) (iv) chain reactions.Temperaturedependence of reaction rates; Arrhenius equation; activation energy. Collision theoryof reaction rates, Lindemann mechanism, qualitative treatment of the theory ofabsolute reaction rates. (18 Lectures)

Catalysis:Types of catalyst, specificity and selectivity, mechanisms of catalyzed reactions at solidsurfaces; effect of particle size and efficiency of nanoparticles as catalysts. Enzymecatalysis, Michaelis-Menten mechanism, acid-base catalysis. (8 Lectures)

Surface chemistry:Physical adsorption, chemisorption, adsorption isotherms. nature of adsorbed state.

(6 Lectures )


1. Peter Atkins & Julio De Paula, Physical Chemistry 9th Ed., Oxford University Press(2010).2. Castellan, G. W. Physical Chemistry, 4th Ed., Narosa (2004).3. McQuarrie, D. A. & Simon, J. D., Molecular Thermodynamics, Viva Books Pvt. Ltd.:New Delhi (2004).4. Engel, T. & Reid, P. Physical Chemistry 3rd Ed., Prentice-Hall (2012).5. Assael, M. J.; Goodwin, A. R. H.; Stamatoudis, M.; Wakeham, W. A. & Will, S.Commonly Asked Questions in Thermodynamics. CRC Press: NY (2011).6. Zundhal, S.S. Chemistry concepts and applications Cengage India (2011).7. Ball, D. W. Physical Chemistry Cengage India (2012).8. Mortimer, R. G. Physical Chemistry 3rd Ed., Elsevier: NOIDA, UP (2009).9. Levine, I. N. Physical Chemistry 6th Ed., Tata McGraw-Hill (2011).


21

10. Metz, C. R. Physical Chemistry 2nd Ed., Tata McGraw-Hill (2009).

Course Title Physics –III

Course Code BSPY304Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of Physics up to 10+2 level.Course objectives The course is an introduction to Thermal Physics, and is designed to impart basic

understanding of the related laws and applications. Course also includes elementaryintroduction of Statistical Mechanics.

Unit-I

Unit-II

Unit-III

Unit-IV

Laws of Thermodynamics: Thermodynamic Description of system: Zeroth Law ofthermodynamics and temperature. First law and internal energy, conversion of heatinto work, Various Thermodynamic Processes, Applications of First Law: GeneralRelation between CP and CV, Work Done during Isothermal and Adiabatic Processes,Compressibility and Expansion Coefficient, Reversible and irreversible processes,Second law and Entropy, Carnot’s cycle & theorem, Entropy changes in reversible &irreversible processes, Entropy-temperature diagrams, Third law of thermodynamics,Unattainability of absolute zero.

Thermodynamic Potentials: Enthalpy, Gibbs, Helmholtz and Internal Energy functions,Maxwell’s relations and applications - Joule-Thomson Effect, Clausius-ClapeyronEquation, Expressions for (CP – CV), CP/CV, TdS equations.

Kinetic Theory of Gases: Maxwell’s law of distribution of velocities and its experimentalverification, Mean free path (Zeroth Order), Transport Phenomena: Viscosity,Conduction and Diffusion (for vertical case), Law of equipartition of energy (withoutderivation of expressions) and its applications to specific heat of gases; mono-atomicand diatomic gases.

Theory of Radiation: Blackbody radiation, Spectral distribution, Concept of EnergyDensity, Derivation of Planck's law, Deduction of Wien’s distribution law, Rayleigh-JeansLaw, Stefan Boltzmann Law and Wien’s displacement law from Planck’s law. StatisticalMechanics: Maxwell-Boltzmann law - distribution of velocity - Quantum statistics -Phase space - Fermi-Dirac distribution law - electron gas - Bose-Einstein distribution law- photon gas - comparison of three statistics.

Text and reference Recommended Books:

1. Thermal Physics, S. Garg, R. Bansal and C. Ghosh, 1993, Tata McGraw-Hill.2. A Treatise on Heat, Meghnad Saha, and B. N. Srivastava, 1969, Indian Press.3. Thermodynamics, Enrico Fermi, 1956, Courier Dover Publications.4. Thermodynamics, Kinetic theory & Statistical thermodynamics, Sears & Salinger,1988, Narosa.5. University Physics, Ronald Lane Reese, 2003, Thomson Brooks/Cole

Course Title Mathematics-III(Numerical Methods and computations)

Course Code BSMA304Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of Maths up to 10+2 level.Course objectives This course introduces types of errors, errors in numerical computations ,Solution of

Algebraic and Transcendental Equation,solution of algebraic and transcendentalequations,numerical differentiation and numerical integration.


22

Unit-I

Unit-II

Unit-III

Unit-IV

Errors: Notions of round off, truncation and other errors, Errors in numericalcomputationsSolution of Algebraic and Transcendental Equations: Bisection, False position, IterativeMethod, Newton Raphson Method, Secant Method. Solution using Matlab.

Solution of system of Linear Equations: Gauss Elimination method, Gauss JordanMethod, LU decomposition method, Gauss Jacobi Method, Gauss Seidel method.Solution using Matlab.Interpolation: Newton’s forward and backward interpolation, Newton’s divideddifference interpolating polynomials, Lagrange Interpolating polynomials. Solutionusing Matlab.

Numerical Differentiation: First and second order differentiation Equations of EquallySpaced Data. Solution using Matlab.Numerical Integration: Trapezoidal rule, Simpson’s one third and 3/8th rule. Solutionusing Matlab.

Numerical methods for Solution of ordinary differential equation: Taylor’s seriesmethod, Euler’s method, Modified Euler’s method, Runge Kutta forth ordered method,Milne’s Predictor Corrector Method. Finite element method to solve second order ODE.Solution using Matlab.Curve Fittings: General Linear Least Squares, Fitting of quadratic and exponentialcurves. Solution using Matlab.

Text and References Reference Books:1. G. Shankar Rao, Numerical Analysis, New Age International Pvt. Ltd, 2006.2. S. S. Sastry, Introductory methods of Numerical Analysis, Prentice-Hall of India, 2006.3. Ralp G. Stanton, Numerical methods for science and Engineering, Prentice-Hall ofIndia, 1967.4. P. C. Biswal, Numerical Analysis, Prentice-Hall of India, 2008.5. Narsingh Deo, Graph theory with applications to Engineering and Computer Science,Prentice-Hall of India, 1993.6. J. P. Trembley and R. Manohar, Discrete Mathematical Structure with applications toComputer Science, Mc Graw Hill Book Company, 2001.

Course Title INTRODUCTION TO IPR, BIOETIHCS & BIOSAFETYCourse Code BSBO304Course Credits L T P Credits

4 2 6Prerequisites Students should have basic knowledge of Biology up to 10+2 level.Course objectives This course indroduces Indian Patent Law, Entrepreneurship,concept of

Bioethics,information about biosafety and health hazards concerning biotechnology.Itwill develop the skill in the biotechnology field.


23

Unit-I

Unit-II

Unit-III

Unit-IV

Introduction to Indian Patent Law. World Trade Organization and its related intellectualproperty provisions. Intellectual/Industrial property and its legalprotection in research,design and development. Patenting in Biotechnology,economic, ethical and depositoryconsiderations . (15 Lectures)

Entrepreneurship: Selection of a product, line, design and development processes,economics on material and energy requirement, stock the product and release thesame for making etc. The basic regulations of excise: Demand for a given product,feasibility of its production under given constraints of raw material, energy input,financial situations export potential etc. (20 Lectures)

Bioethics – Necessity of Bioethics, different paradigms of Bioethics – National &International. Ethical issues against the molecular technologies. (10 Lectures)

Biosafety– Introduction to biosafety and health hazards concerning biotechnology.Introduction to the concept of containment level and Good Laboratory Practices (GLP)and Good Manufacturing Practices (GMP). (15 Lectures)

Text and References Reference Books:1. Entrepreneurship: New Venture Creation : David H. Holt2. Patterns of Entrepreneurship : Jack M. Kaplan3. Entrepreneurship and Small Business Management: C.B. Gupta, S.S. Khanka, SultanChand & Sons.4. Sateesh MK (2010) Bioethics and Biosafety, I. K. International Pvt Ltd.

Course Title General Aptitude and Logical reasoningCourse Code BSCM305Course Credits L T P Credits

2 0 0 2Courseobjectives

This course gives the chance of an opprtunity to demonstrate student’s ability andoutcompete other applicants through different types of basic shortcut tricks in mathematics.

Unit-I

Unit-II

1. Basic Shortcut TricksAddition TricksMultiplication TricksDivision Tricks

2. Square and Cube TricksSquare and Square root TricksCube and Cube root Tricks (20 Lectures)

1. Number Series2. Percentage3. Profit and loss4. Simple interest and Compound Interest5. Average6. Ratio and proportion7. Problems based on Ages8. Problems on Trains9. Speed Time and Distance10. Probability Tricks11. Permutation and Combination12. Mensuration13. Logical Reasoning (10Lectures)


24

Course Title FUEL CHEMISTRY


2 0 0 2Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course discribes the subject of chemistry which concerns the use of coal in

different industries, the study and introduction of petrochemicals, classification oflubricants and its application.

Unit-I

Unit-II

Coal: Uses of coal (fuel and nonfuel) in various industries, its composition, carbonizationof coal.Coal gas, producer gas and water gas—composition and uses. Fractionation ofcoal tar, uses of coal tar bases chemicals, requisites of a good metallurgical coke, Coalgasification (Hydro gasification and Catalytic gasification), Coal liquefaction and SolventRefining. (10 Lectures)

Petroleum and Petrochemical Industry: Composition of crude petroleum, Refining anddifferent types of petroleum products and their applications.Fractional Distillation (Principle and process), Cracking (Thermal and catalytic cracking),Reforming Petroleum and non-petroleum fuels (LPG, CNG, LNG, bio-gas, fuels derivedfrom biomass), fuel from waste, synthetic fuels (gaseous and liquids), clean fuels.Petrochemicals: Vinyl acetate, Propylene oxide, Isoprene, Butadiene, Toluene and itsderivatives Xylene.Lubricants: Classification of lubricants, lubricating oils (conducting and non-conducting)Solid and semisolid lubricants, synthetic lubricants.Properties of lubricants (viscosity index, cloud point, pore point) (20 lectures)


1. E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.2. P.C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.3. B.K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.

SEM-IVCourse Title Inorganic Chemistry – IICourse Code BSCM401Course Credits L T P Credits

4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives The course deals with the idea about the coordination chemistry ,chemistry of

transition elements,lanthanoids and actinoids.In addition, it also includes the role ofmetals in biology .

Unit-I

Unit-II

Coordination Chemistry:Werner’s theory, valence bond theory (inner and outer orbital complexes),electroneutrality principle and back bonding. Crystal field theory, measurement of 10Dq (o), CFSE in weak and strong fields, pairing energies, factors affecting the magnitudeof 10 Dq (o,t). Octahedral vs. tetrahedral coordination, tetragonal distortions fromoctahedral geometry Jahn-Teller theorem, square planar geometry. Qualitative aspectof Ligand field and MO Theory.IUPAC nomenclature of coordination compounds, isomerism in coordinationcompounds. Stereochemistry of complexes with 4 and 6 coordination numbers. Chelateeffect,polynuclear complexes, Labile and inert complexes. (26 Lectures)

Transition Elements:General group trends with special reference to electronic configuration, colour,


25

Unit-III

Unit-IV

variable valency, magnetic and catalytic properties, ability to form complexes. Stabilityof various oxidation states and e.m.f. (Latimer & Bsworth diagrams). Differencebetween the first, second and third transition series.Chemistry of Ti, V, Cr Mn, Fe and Co in various oxidation states (excluding theirmetallurgy) (18 Lectures)

Lanthanoids and Actinoids:Electronic configuration, oxidation states, colour, spectral and magnetic properties,lanthanide contraction, separation of lanthanides (ion-exchange method only).

(6 Lectures)

Bioinorganic Chemistry:Metal ions present in biological systems, classification of elements according to theiraction in biological system. Geochemical effect on the distribution of metals. Sodium /K-pump, carbonic anhydrase and carboxypeptidase. Excess and deficiency of sometrace metals. Toxicity of metal ions (Hg, Pb, Cd and As), reasons for toxicity, Use ofchelating agents in medicine.Iron and its application in bio-systems, Haemoglobin; Storage and transfer of iron.

(10 Lectures)


1. Purcell, K.F & Kotz, J.C. Inorganic Chemistry W.B. Saunders Co, 1977.2. Huheey, J.E., Inorganic Chemistry, Prentice Hall, 1993.3. Lippard, S.J. & Berg, J.M. Principles of Bioinorganic Chemistry Panima PublishingCompany 1994.4. Cotton, F.A. & Wilkinson, G, Advanced Inorganic Chemistry. Wiley-VCH, 19995. Basolo, F, and Pearson, R.C., Mechanisms of Inorganic Chemistry, John Wiley &Sons, NY, 1967.6. Greenwood, N.N. & Earnshaw A., Chemistry of the Elements,Butterworth-Heinemann,1997.

Course Title ORGANIC CHEMISTRY-III


4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course involves the information and chemistry of Nitrogen Containing Functional

Groups, Effect of substituent and solvent on basicity,preparation and derivatives ofpolynuclear hydrocarbons.It also imparts the basics of heterocyclic chemistry andvarious type of alkaloids found in nature.

Unit-I

Unit-II

Nitrogen Containing Functional GroupsPreparation and important reactions of nitro and compounds, nitriles and isonitrilesAmines: Effect of substituent and solvent on basicity; Preparation and properties:Gabriel phthalimide synthesis, Carbylamine reaction, Mannich reaction, Hoffmann’sexhaustive methylation, Hofmann-elimination reaction; Distinction between 1°, 2° and3° amines with Hinsberg reagent and nitrous acid. Diazonium Salts: Preparation andtheir synthetic applications. (18 Lectures)

Polynuclear HydrocarbonsReactions of naphthalene phenanthrene and anthracene Structure, Preparation andstructure elucidation and important derivatives of naphthalene and anthracene;Polynuclear hydrocarbons. (8 Lectures)


26

Unit-III

Unit-IV

Unit-V

Heterocyclic CompoundsClassification and nomenclature, Structure, aromaticity in 5-numbered and6-membered rings containing one heteroatom; Synthesis, reactions and mechanism ofsubstitution reactions of: Furan, Pyrrole (Paal-Knorr synthesis, Knorr pyrrole synthesis,Hantzsch synthesis), Thiophene, Pyridine (Hantzsch synthesis), Pyrimidine, Structureelucidation of indole, Fischer indole synthesis and Madelung synthesis), Structureelucidation of quinoline and isoquinoline, Skraup synthesis, Friedlander’s synthesis,Knorr quinoline synthesis, Doebner-Miller synthesis, Bischler-Napieralski reaction,Pictet-Spengler reaction, Pomeranz-Fritsch reactionDerivatives of furan: Furfural and furoic acid. (22 Lectures)

AlkaloidsNatural occurrence, General structural features, Isolation and their physiological actionHoffmann’s exhaustive methylation, Emde’s modification, Structure elucidation andsynthesis of Hygrine and Nicotine. Medicinal importance of Nicotine, Hygrine, Quinine,Morphine, Cocaine, and Reserpine. (6 Lectures)

TerpenesOccurrence, classification, isoprene rule; Elucidation of stucture and synthesis of Citral,Neral and α-terpineol. (6 Lectures)


1. Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.(Pearson Education).2. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (PearsonEducation).3. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry ofNatural Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).4. Acheson, R.M. Introduction to the Chemistry of Heterocyclic compounds, John Welly& Sons (1976).5. Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.6. Kalsi, P. S. Textbook of Organic Chemistry 1st Ed., New Age International (P) Ltd. Pub.7. Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, OxfordUniversity Press.8. Singh, J.; Ali, S.M. & Singh, J. Natural Product Chemistry, Prajati Parakashan (2010).

Course Title Physical Chemistry – III


4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course describes the principle and working of conductometer,different types of

conductivity,quantitative aspects of electrochemistry,magnetic properties of molecules.

Unit-I ConductanceArrhenius theory of electrolytic dissociation. Conductivity, equivalent and molarconductivity and their variation with dilution for weak and strong electrolytes. Molarconductivity atinfinite dilution. Kohlrausch law of independent migration of ions.Debye-Hückel-Onsager equation, Wien effect, Debye-Falkenhagen effect, Walden’srules.Ionic velocities, mobilities and their determinations, transference numbers and theirrelation to ionic mobilities, determination of transference numbers using Hittorf andMoving Boundary methods. Applications of conductance measurement: (i) degree ofdissociation of weak electrolytes, (ii) ionic product of water (iii) solubility and solubilityproduct of sparingly soluble salts, (iv) conductometric titrations, and (v) hydrolysis


27

Unit-II

Unit-III

constants of salts. (20 Lectures)

ElectrochemistryQuantitative aspects of Faraday’s laws of electrolysis, rules of oxidation/reduction ofions based on half-cell potentials, applications of electrolysis in metallurgy andindustry.Chemical cells, reversible and irreversible cells with examples. Electromotive force of acell and its measurement, Nernst equation; Standard electrode (reduction) potentialand its application to different kinds of half-cells. Application of EMF measurements indetermining (i) free energy, enthalpy and entropy of a cell reaction, (ii) equilibriumconstants, and (iii) pH values, using hydrogen, quinone-hydroquinone, glass andSbO/Sb2O3 electrodes. Concentration cells with and without transference, liquidjunction potential; determination of activity coefficients and transference numbers.Qualitative discussion of potentiometric titrations (acid-base, redox, precipitation).

(28 Lectures)

Electrical & Magnetic Properties of Atoms and MoleculesBasic ideas of electrostatics, Electrostatics of dielectric media, Clausius-Mosottiequation, Lorenz-Laurentz equation, Dipole moment and molecular polarizabilities andtheir measurements. Diamagnetism, paramagnetism, magnetic susceptibility and itsmeasurement, molecular interpretation. (12 Lectures)


1. Atkins, P.W & Paula, J.D. Physical Chemistry, 9th Ed., Oxford University Press (2011).2. Castellan, G. W. Physical Chemistry 4th Ed., Narosa (2004).3. Mortimer, R. G. Physical Chemistry 3rd Ed., Elsevier: NOIDA, UP (2009).4. Barrow, G. M., Physical Chemistry 5th Ed., Tata McGraw Hill: New Delhi (2006).5. Engel, T. & Reid, P. Physical Chemistry 3rd Ed., Prentice-Hall (2012).6. Rogers, D. W. Concise Physical ChemistryWiley (2010).7. Silbey, R. J.; Alberty, R. A. & Bawendi, M. G. Physical Chemistry 4th Ed., John Wiley &Sons, Inc. (2005).


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Course Title Physics – IV

Course Code BSPY404

Course Credits L T P Credits4 0 2 6

Prerequisites Students should have basic knowledge of physics up to 10+2 level.Course objectives The course is an introduction to wave phenomena, and is designed to impart basic

understanding of the related laws and applications.

Unit – I

Unit – II

Unit – III

Unit – IV

Superposition of Two Collinear Harmonic oscillations: Linearity & SuperpositionPrinciple. (1) Oscillations having equal frequencies and (2) Oscillations having differentfrequencies (Beats). Superposition of Two Perpendicular Harmonic Oscillations:Graphical and Analytical Methods. Lissajous Figures (1:1 and 1:2) and their uses. WavesMotion - General: Transverse waves on a string. Travelling and standing waves on astring. Normal Modes of a string. Group velocity, Phase velocity. Plane waves. Sphericalwaves, Wave intensity.

Sound: Simple harmonic motion - forced vibrations and resonance - Fourier’s Theorem -Application to sawtooth wave and square wave - Intensity and loudness of sound -Decibels - Intensity levels - musical notes - musical scale. Acoustics of buildings:Reverberation and time of reverberation - Absorption coefficient - Sabine’s formula -measurement of reverberation time - Acoustic aspects of halls and auditoria

Wave Optics: Electromagnetic nature of light. Definition and Properties of wavefront.Huygens Principle. Interference: Interference: Division of amplitude and division ofwavefront. Young’s Double Slit experiment. Fresnel’s Biprism. Phase change onreflection: Stokes’ treatment. Interference in Thin Films: parallel and wedge-shapedfilms. Fringes of equal inclination (Haidinger Fringes); Fringes of equal thickness (FizeauFringes). Newton’s Rings: measurement of wavelength and refractive index.Michelson’s Interferometer: (1) Idea of form of fringes (no theory needed), (2)Determination of wavelength, (3) Wavelength difference, (4) Refractive index, and (5)Visibility of fringes

Wave Optics: Diffraction: Fraunhofer diffraction- Single slit; Double Slit. Multiple slitsand Diffraction grating. Fresnel Diffraction: Half-period zones. Zone plate. FresnelDiffraction pattern of a straight edge, a slit and a wire using half-period zone analysis.Polarization: Transverse nature of light waves. Plane polarized light – production andanalysis. Circular and elliptical polarization.


1. Fundamentals of Optics, F. A. Jenkins and H. E White, 1976, McGraw-Hill.2. Principles of Optics, B. K. Mathur, 1995, Gopal Printing.3. Fundamentals of Optics, H. R. Gulati and D. R. Khanna, 1991, R. Chand Publications.4. University Physics, F. W. Sears, M. W. Zemansky and H. D. Young. 13/e, 1986,Addison-Wesley.


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Course Title Mathematics-IV( Operation Research )

Course Code BSMA404Course Credits L T P Credits

5 1 0 6Prerequisites Students should have basic knowledge of Mathematics up to 10+2 level.

Unit-I

Unit-II

Unit-III

Unit-IV

Unit-V

General discussions of Linear programming problems and their illustrations, Graphicalmethod of solving two variable problem, Convex sets and their properties, Feasiblesolution, optimum solution, Slack and Surplus variables, L.P.P. in a standard form,Properties of a solution (without proof), Simplex method and its computationalprocedure, Artificial basis technique. (15 lectures)

Transportation problem, Methods for finding initial basic feasible solution: Northwestcorner rule, Matrix minima method, Vogel’s approximation method, optimal solution:MODI Method. Assignment problem: Hungarian Method. (15 lectures)

Project Management (PERT): Construction of networks, Network computations, Floats(free floats and total floats), Critical path method (CPM), Crashing. (15 lectures)

Game Theory: Definitions, Rules for Game Theory, Dominance Principle, Two-personzero-sum game, Game with mixed strategies, Graphical method. (15 lectures)

Sequencing Problem, Assumptions, Processing n jobs through 1 machine, 2 machinesand 3 machines, Processing 2 jobs through m machines, Processing n jobs through mmachines. (20 lectures)

Text and References Reference Books :1. Erwin Kreyszig, Advanced Engineering Mathematics, John Wiley and Sons Inc., 1983.2. Louis Leithold, The Calculus with Analytic Geometry, Harper-Collins Publishers,

1981.3. Shanti Narayan, Differential Calculus, S. Chand & Co. Ltd., 2005.4. G. B. Thomas Jr. and R. L. Finney, Calculus and Analytic Geometry, Addison-Wesley

Publishers, 1999. 8. David V. Widder, Advanced Calculus, Prentice-Hall of India,1989.

5. S. I. Gass, Linear programming, Mc Graw Hill Book Company, 1985.6. Kanti Swaroop, Man Mohan and P.K. Gupta, Operations Research, Sultan Chand

and Sons, 2005.7. Hamdy A. Taha, Operations Research: An Introduction, McMillan Publishing

Company, 2007.

Course Title ENTERPRENEURSHIP DEVELOPMENTCourse Code BSBO404Course Credits L T P Credits

2 1 0 2Course objectives This course introduces students to the theory of entrepreneurship and its practical

implementation. It focuses on different stages related to the entrepreneurial process,including business model innovation, monetization, small business management as wellas strategies that improve performance of new business ventures.

Unit-I IntroductionMeaning, Needs and Importance of Entrepreneurship, Promotion of entrepreneurship,Factors influencing entrepreneurship, Features of a successful Entrepreneurship.

(10 Periods)


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Unit-II

Unit-III

Unit-IV

Unit-V

Establishing an EnterpriseForms of Business Organization, Project Identification, Selection of the product, Projectformulation, Assessment of project feasibility. (12 lectures)

Financing the EnterpriseImportance of finance / loans and repayments, Characteristics of Business finance,Fixed capital management: Sources of fixed capital, working capital its sources andhow to move for loans, Inventory direct and indirect raw materials and itsmanagement. (15 lectures)

Marketing ManagementMeaning and Importance, Marketing-mix, product management – Product line, Productmix, stages of product like cycle, marketing Research and Importance of survey,PhysicalDistribution and Stock Management. (13 lectures)

Entrepreneurship and International BusinessMeaning of International business, Selection of a product, Selection of a marketfor international business, Export financing, Institutional support for exports.

(10 Periods)Project Report on a selected product should be prepared and submitted.

Text and References Reference Books:1. Entrepreneurship: New Venture Creation : David H. Holt2. Patterns of Entrepreneurship : Jack M. Kaplan3. Entrepreneurship and Small Business Management: C.B. Gupta, S.S. Khanka,

Sultan Chand & Sons.4. Sateesh MK (2010) Bioethics and Biosafety, I. K. International Pvt Ltd.

Course Title Introduction to Statistics


2 0 0 2Prerequisites Students should have basic knowledge of Statistics up to 10+2 level.Course objectives This course defines the Basics of Statistics,data analysis,survey and sampling.

Unit-I

Unit-II

Introduction to Statistics, Collection and Presentation of Data, Types of Data,Tabulation presentation of data, Summarization of Data, Frequency distribution ofvariables, Graphical representation of the frequency distribution, Types of distribution,Measures of central tendency, Measures of Dispersion.

Data on two or more attributes, Independence and association, bivariate data, Scatterdiagram, Correlation Analysis, Regression Analysis distribution, Types of distribution,Measures of central tendency, Measures of Dispersion.


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SEM-V

Course Title Organic Chemistry – IV


4 0 2 6Prerequisites Students should have basic knowledge of chemistry up to 10+2 level.Course objectives This course defines the large macromolecules such as Carbohydrates, Proteins, Lipids,

Nucleic acids, Enzymes involving the introduction, biological functions,purification andtheir reactivity to get general information in terms of biochemistry, Concept of Energyin Biosystems,Pharmaceutical Compounds: Structure and Importance.

Unit-I

Unit-II

Unit-III

Unit-IV

Unit-V

Unit-VI

Nucleic AcidsComponents of nucleic acids, Nucleosides and nucleotides;Structure, synthesis and reactions of: Adenine, Guanine, Cytosine, Uracil and Thymine;Structure of polynucleotides. (9 Lectures)

Amino Acids, Peptides and ProteinsAmino acids, Peptides and their classification.α-Amino Acids - Synthesis, ionic properties and reactions. Zwitterions, pKa values,isoelectric point and electrophoresis;Study of peptides: determination of their primary structures-end group analysis,methods of peptide synthesis. Synthesis of peptides using N-protecting, C-protectingand C-activating groups -Solid-phase synthesis. (16 Lectures)

EnzymesIntroduction, classification and characteristics of enzymes. Salient features of active siteof enzymes.Mechanism of enzyme action (taking trypsin as example), factors affecting enzymeaction, coenzymes and cofactors and their role in biological reactions, specificity ofenzyme action (including stereospecificity), enzyme inhibitors and their importance,phenomenon of inhibition (competitive, uncompetitive and non-competitive inhibitionincluding allosteric inhibition). (8 Lectures)

LipidsIntroduction to oils and fats; common fatty acids present in oils and fats,Hydrogenntion of fats and oils, Saponification value, acid value, iodine number.Reversion and rancidity. (5 Lectures)

Concept of Energy in BiosystemsCells obtain energy by the oxidation of foodstuff (organic molecules).Introduction to metabolism (catabolism, anabolism).ATP: The universal currency of cellular energy, ATP hydrolysis and free energy change.Agents for transfer of electrons in biological redox systems: NAD+, FAD.Conversion of food to energy: Outline of catabolic pathways of carbohydrate-glycolysis, fermentation, Krebs cycle.Overview of catabolic pathways of fat and protein.Interrelationship in the metabolic pathways of protein, fat and carbohydrate. Caloricvalue of food, standard caloric content of food types. (7Lectures)

Pharmaceutical Compounds: Structure and ImportanceClassification, structure and therapeutic uses of antipyretics: Paracetamol (withsynthesis),Analgesics: Ibuprofen (with synthesis), Antimalarials: Chloroquine (withsynthesis). An elementary treatment of Antibiotics and detailed study ofchloramphenicol, Medicinal values of curcumin (haldi), azadirachtin (neem), vitamin Cand antacid (ranitidine). (12 Lectures)


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1. Berg, J.M., Tymoczko, J.L. and Stryer, L. (2006) Biochemistry. VIth Edition. W.H.Freeman and Co.2. Nelson, D.L., Cox, M.M. and Lehninger, A.L. (2009) Principles of Biochemistry. IVEdition. W.H. Freeman and Co.3. Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W. (2009) Harper’sIllustrated Biochemistry. XXVIII edition. Lange Medical Books/ McGraw-Hill.

Course Title Physical Chemistry – V


4 0 2 6Prerequisites --Course objectives The course is an introduction to Quantum chemistry, and is designed to impart basic

understanding of Molecular Spectroscopy and photochemistry.

Unit-I

Unit-II

Quantum ChemistryPostulates of quantum mechanics, quantum mechanical operators, Schrödingerequation and its application to free particle and “particle-in-a-box” (rigoroustreatment), quantization of energy levels, zero-point energy and HeisenbergUncertainty principle; wavefunctions, probability distribution functions, nodalproperties, Extension to two and three dimensional boxes, separation of variables,degeneracy.

Qualitative treatment of simple harmonic oscillator model of vibrational motion:Setting up of Schrödinger equation and discussion of solution and wavefunctions.Vibrational energy of diatomic molecules and zero-point energy.Angular momentum:Commutation rules, quantization of square of total angular momentum andz-component.Rigid rotator model of rotation of diatomic molecule. Schrödinger equation,transformation to spherical polar coordinates. Separation of variables. Sphericalharmonics. Discussion of solution.Qualitative treatment of hydrogen atom and hydrogen-like ions: setting up ofSchrödinger equation in spherical polar coordinates, radial part, quantization of energy(only final energy expression). Average and most probable distances of electron fromnucleus.

Setting upof Schrödinger equation for many-electron atoms (He, Li). Need forapproximation methods. Statement of variation theorem and application to simplesystems (particle-in-a-box, harmonic oscillator, hydrogen atom).

Chemical bonding: Covalent bonding, valence bond and molecular orbital approaches,LCAO-MO treatment of H2 +. Bonding and antibonding orbitals. Qualitative extension toH2. Comparison of LCAO-MO and VB treatments of H2 (only wavefunctions, detailedsolution not required) and their limitations. Refinements of the two approaches(Configuration Interaction for MO, ionic terms in VB). Qualitative description ofLCAO-MO treatment of homonuclear and heteronuclear diatomic molecules (HF, LiH).Localised and non-localised molecular orbitals treatment of triatomic (BeH2, H2O)molecules. Qualitative MO theory and its application to AH2 type molecule.

(24 Lectures)

Molecular SpectroscopyInteraction of electromagnetic radiation with molecules and various types of spectra;Born-Oppenheimer approximation.Rotation spectroscopy: Selection rules, intensities of spectral lines, determination ofbond lengths of diatomic and linear triatomic molecules, isotopic substitution.

Vibrational spectroscopy: Classical equation of vibration, computation of force


33

Unit-II

constant, amplitude of diatomic molecular vibrations, anharmonicity, Morse potential,dissociation energies, fundamental frequencies, overtones, hot bands, degrees offreedom for polyatomic molecules, modes of vibration, concept of group frequencies.Vibration-rotation spectroscopy: diatomic vibrating rotator, P, Q, R branches.

Raman spectroscopy: Qualitative treatment of Rotational Raman effect; Effect ofnuclear spin, Vibrational Raman spectra, Stokes and anti-Stokes lines; their intensitydifference, rule of mutual exclusion.

Electronic spectroscopy: Franck-Condon principle, electronic transitions, singlet andtriplet states, fluorescence and phosphorescence, dissociation and predissociation,calculation of electronic transitions of polyenes using free electron model.

Nuclear Magnetic Resonance (NMR) spectroscopy: Principles of NMR spectroscopy,Larmor precession, chemical shift and low resolution spectra, different scales, spin-spincoupling and high resolution spectra, interpretation of PMR spectra of organicmolecules.

Electron Spin Resonance (ESR) spectroscopy: Its principle, hyperfine structure, ESR ofsimple radicals. (24 Lectures)

PhotochemistryCharacteristics of electromagnetic radiation, Lambert-Beer’s law and its limitations,physical significance of absorption coefficients. Laws, of photochemistry, quantumyield, actinometry, examples of low and high quantum yields, photochemicalequilibrium and the differential rate of photochemical reactions, photosensitisedreactions, quenching. Role of photochemicalreactions in biochemical processes,photostationary states, chemiluminescence. (12 Lectures)


1. Banwell, C. N. & McCash, E. M. Fundamentals of Molecular Spectroscopy 4th Ed. TataMcGraw-Hill: New Delhi (2006).2. Chandra, A. K. Introductory Quantum Chemistry Tata McGraw-Hill (2001).3. House, J. E. Fundamentals of Quantum Chemistry 2nd Ed. Elsevier: USA (2004).4. Lowe, J. P. & Peterson, K. Quantum Chemistry, Academic Press (2005).5. Kakkar, R. Atomic & Molecular Spectroscopy, Cambridge University Press (2015).

Course Title INDUSTRIAL CHEMISTRY


4 0 2 6Course objectives This course provides an inroduction to management practices in chemistry.The course

provides the iomportant information regarding basic tools to design industrial gasesand chemicals.It covers the information about matallurgy and Environment and itssegments and biocatalysis at industrial level.Extensive use is made of industrialexamples and analogies between the various transport mechanism to encourage lateralthinking.

Unit-I Industrial Gases and Inorganic ChemicalsIndustrial Gases: Large scale production, uses, storage and hazards in handling ofthe following gases: oxygen, nitrogen, argon, neon, helium, hydrogen, acetylene,carbon monoxide, chlorine, fluorine, sulphur dioxide and phosgene.Inorganic Chemicals: Manufacture, application, analysis and hazards in handling thefollowing chemicals: hydrochloric acid, nitric acid, sulphuric acid, caustic soda, commonsalt, borax, bleaching powder, sodium thiosulphate, hydrogen peroxide, potash alum,chrome alum, potassium dichromate and potassium permanganate. (10 Lectures)


34

Unit-II

Unit-III

Unit-IV

Unit-V

Industrial MetallurgyPreparation of metals (ferrous and nonferrous) and ultrapure metals forsemiconductor technology. (4 Lectures)

Environment and its segmentsEcosystems. Biogeochemical cycles of carbon, nitrogen and sulphur.Air Pollution: Major regions of atmosphere. Chemical and photochemical reactionsin atmosphere. Air pollutants: types, sources, particle size and chemical nature;Photochemical smog: its constituents and photochemistry. Environmental effects ofozone, Major sources of air pollution.

Pollution by SO2 , CO2, CO, NOx, H2S and other foul smelling gases. Methods ofestimation of CO, NOx, SOx and control procedures.

Effects of air pollution on living organisms and vegetation. Greenhouse effect andGlobal warming, Ozone depletion by oxides of nitrogen, chlorofluorocarbons andHalogens, removal of sulphur from coal. Control of particulates.

Water Pollution: Hydrological cycle, water resources, aquatic ecosystems, Sources andnature of water pollutants, Techniques for measuring water pollution, Impacts of waterpollution on hydrological and ecosystems.

Water purification methods. Effluent treatment plants (primary, secondary and tertiarytreatment). Industrial effluents from the following industries and their treatment:electroplating, textile, tannery, dairy, petroleum and petrochemicals, agro, fertilizer,etc. Sludge disposal.

Industrial waste management, incineration of waste. Water treatment and purification(reverse osmosis, electro dialysis, ion exchange). Water quality parameters for wastewater, industrial water and domestic water. (30 Lectures)

Energy & EnvironmentSources of energy: Coal, petrol and natural gas. Nuclear Fusion / Fission, Solar energy,Hydrogen, geothermal, Tidal and Hydel, etc.

Nuclear Pollution: Disposal of nuclear waste, nuclear disaster and its management.(10 Lectures)

CorrosionIntroduction – Definition of Corrosion , overall classification of types of corrosion.

(6 Lectures)


1. E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.2. R.M. Felder, R.W. Rousseau: Elementary Principles of Chemical Processes, WileyPublishers, New Delhi.3. J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.4. S. S. Dara: A Textbook of Engineering Chemistry, S. Chand & Company Ltd. New Delhi.5. K. De, Environmental Chemistry: New Age International Pvt., Ltd, New Delhi.6. S. M. Khopkar, Environmental Pollution Analysis: Wiley Eastern Ltd, New Delhi.7. S.E. Manahan, Environmental Chemistry, CRC Press (2005).8. G.T. Miller, Environmental Science 11th edition. Brooks/ Cole (2006).9. A. Mishra, Environmental Studies. Selective and Scientific Books, New Delhi (2005)


35

Course Title GREEN CHEMISTRYCourse Code BSCM504Course Credits L T P Credits

4 0 2 6Courseobjectives

This course is defined to introduce green chemistry, Principles of Green Chemistry andDesigning a Chemical synthesis, microwave assisted organic reactions.

Unit-I

Unit-II

Unit-III

Unit-IV

Introduction to Green ChemistryWhat is Green Chemistry? Need for Green Chemistry. Goals of GreenChemistry. Limitations/ Obstacles in the pursuit of the goals of Green Chemistry. (4 Lectures)

Principles of Green Chemistry and Designing a Chemical synthesisTwelve principles of Green Chemistry with their explanations and examples; Designing aGreen Synthesis using these principles; Prevention of Waste/ byproducts; maximumincorporation of the materials used in the process into the final products (Atom Economy);prevention/ minimization of hazardous/ toxic products; designing safer chemicals – differentbasic approaches to do so; selection of appropriate auxiliary substances (solvents, separationagents), green solvents, solventless processes, immobilized solvents and ionic liquids;

(24 Lectures)

Examples of Green Synthesis/ Reactions1. Green Synthesis of the following compounds: adipic acid, catechol, BHT, methylmethacrylate, urethane, aromatic amines (4-aminodiphenylamine), benzyl bromide,acetaldehyde, disodium iminodiacetate (alternative to Strecker synthesis), citral, ibuprofen,paracetamol, furfural.2. Microwave assisted reactions in water: Hofmann Elimination, Hydrolysis (of benzylchloride, benzamide, n-phenyl benzamide, methylbenzoate to benzole acid), Oxidation (oftoluene, alcohols). Microwave assisted reactions in organic solvents: Esterification, Friesrearrangement, Orthoester Claisen Rearrangement, Diels-Alder Reaction, Decarboxylation.Microwave assisted solid state reactions: Deacetylation, Deprotection. Saponification ofesters, Alkylation of reactive methylene compounds, reductions, synthesis of nitriles fromaldehydes; anhydrides from dicarboxylic acid; pyrimidine and pyridine derivatives;1,2-dihydrotriazine derivatives; benzimidazoles.3. Ultrasound assisted reactions: Esterification, saponification, substitution reactions,Alkylations, oxidation, reduction, coupling reaction, Cannizaro reaction, Strecker synthesis,Reformatsky reaction.4. Selective methylation of active methylene group using dimethylcarbonate: Solid-statepolymerization of amorphous polymers using diphenylcarbonate; Use of “Clayan”, anonmetallic oxidative reagent for various reactions; Free Radical Bromination; Role ofTellurium in organic syntheses; Biocatalysis in organic syntheses. (24 Lectures)

Future Trends in Green ChemistryOxidation reagents and catalysts; Biomimetic, multifunctional reagents; Combinatorial greenchemistry; Proliferation of solventless reactions; oncovalent derivatization; Green chemistry insustainable development. (8 Lectures)

Text andReferences

Reference Books:

1. V.K. Ahluwalia & M.R. Kidwai: New Trends in Green Chemistry,2. Anamalaya Publishers (2005).3. P.T. Anastas & J.K. Warner: Oxford Green Chemistry- Theory and Practical, University Press(1998).4. A.S. Matlack: Introduction to Green Chemistry, Marcel Dekker (2001).5. M.C. Cann & M.E. Connely: Real-World cases in Green Chemistry, American ChemicalSociety, Washington (2000).6. M.A. Ryan & M. Tinnesand, Introduction to Green Chemistry, American Chemical Society,Washington (2002).


36

Course Title NOVEL INORGANIC SOLIDS


4 0 2 6Course objectives This course is in consideration of Synthesis and modification of inorganic solids of

technological importance. Overview of nanostructures. Introduction to engineeringmaterials for mechanical construction, Composite materials, Speciality polymers.

Unit-I

Unit-II

Unit-III

Unit-IV

Unit-V

Unit-VI

Synthesis and modification of inorganic solidsConventional heat and beat methods, Co-precipitation method, Sol-gel methods,Hydrothermal method, Ion-exchange and Intercalation methods. (10 Lectures)

Inorganic solids of technological importance:Solid electrolytes – Cationic, anionic, mixed Inorganic pigments – coloured solids, whiteand black pigments.Molecular material and fullerides, molecular materials & chemistry – one-dimensionalmetals, molecular magnets, inorganic liquid crystals. (10 Lectures)

Nanomaterials:Overview of nanostructures and nanomaterials: classification.Preparation of gold and silver metallic nanoparticles, self-assemblednanostructures-control of nanoarchitecture-one dimensional control. Carbonnanotubes and inorganic nanowires. Bio-inorganic nanomaterials, DNA andnanomaterials, natural and antisical nanomaterials, bionano composites.(10 Lectures)

Introduction to engineering materials for mechanical construction:Composition, mechanical and fabricating characteristics and applications of varioustypes of cast irons, plain carbon and alloy steels, copper, aluminum and their alloys likeduralumin, brasses and bronzes cutting tool materials, super alloys thermoplastics,thermosets and composite materials. (10 Lectures)

Composite materials:Introduction, limitations of conventional engineering materials, role of matrix incomposites, classification, matrix materials, reinforcements, metal-matrix composites,polymer-matrix composites, fibre- reinforced composite , environmental effects oncomposites, applications of composites. (10 Lectures)

Speciality polymers:Conducting polymers - Introduction, conduction mechanism, polyacetylene,polyparaphenylene and polypyrole, applications of conducting polymers, Ion-exchangeresins and their applications. Ceramic & Refractory: Introduction, classification,properties, raw materials, manufacturing and applications. (10 Lectures)


1. Shriver & Atkins. Inorganic Chemistry, Peter Alkins, Tina Overton, Jonathan Rourke,Mark Weller and Fraser Armstrong, 5th Edition, Oxford University Press (2011-2012)2. Adam, D.M. Inorganic Solids: An introduction to concepts in solid-state structuralchemistry.3. Frank J. Ovens, Introduction to Nanotechnology.


37

SEM-VICourse Title Organic Chemistry – V


4 0 2 6Course objectives The course is formulated to learn the fundamentals of organic spectroscopic

techniques such as UV,IR,NMR.It also includes the Occurrence, classification and theirbiological importance of carbohydrates. It involves the introduction, synthesis andapplications of dyes and polymers.

Unit-I

Unit-II

Unit-III

Unit-IV

Organic SpectroscopyGeneral principles Introduction to absorption and emission spectroscopy.

UV Spectroscopy: Types of electronic transitions, λ max, Chromophores andAuxochromes, Bathochromic and Hypsochromic shifts, Intensity of absorption;Application of Woodward Rules for calculation of λmax for the following systems: α,βunsaturated aldehydes, ketones, carboxylic acids and esters; Conjugated dienes:alicyclic, homoannular and heteroannular; Extended conjugated systems (aldehydes,ketones and dienes); distinction between cis and trans isomers.

IR Spectroscopy: Fundamental and non-fundamental molecular vibrations; IRabsorption positions of O, N and S containing functional groups; Effect of H-bonding,conjugation, resonance and ring size on IR absorptions; Fingerprint region and itssignificance; application in functional group analysis.

NMR Spectroscopy: Basic principles of Proton Magnetic Resonance, chemical shift andfactors influencing it; Spin – Spin coupling and coupling constant; Anisotropic effects inalkene, alkyne, aldehydes and aromatics, Interpetation of NMR spectra of simplecompounds.

Applications of IR, UV and NMR for identification of simple organic molecules.(24 Lectures)

CarbohydratesOccurrence, classification and their biological importance.

Monosaccharides: Constitution and absolute configuration of glucose and fructose,epimers and anomers, mutarotation, determination of ring size of glucose and fructose,Haworth projections and conformational structures; Interconversions of aldoses andketoses; Killiani-Fischer synthesis and Ruff degradation;

Disaccharides – Structure elucidation of maltose, lactose and sucrose.

Polysaccharides – Elementary treatment of starch, cellulose and glycogen. (16 Lectures)

DyesClassification, Colour and constitution; Mordant and Vat Dyes; Chemistry ofdyeing; Synthesis and applications of: Azo dyes – Methyl Orange and Congo Red(mechanism of Diazo Coupling); Triphenyl Methane Dyes -Malachite Green, Rosanilineand Crystal Violet; Phthalein Dyes – Phenolphthalein and Fluorescein; Naturaldyes –structure elucidation and synthesis of Alizarin and Indigotin; Edible Dyes withexamples

(8 Lectures)PolymersIntroduction and classification including di-block, tri-block and amphiphilic polymers;Number average molecular weight, Weight average molecular weight, Degree of


38

polymerization, Polydispersity Index.Polymerisation reactions -Addition and condensation -Mechanism of cationic, anionicand free radical addition polymerization; Metallocene-based Ziegler-Nattapolymerisation of alkenes; Preparation and applications of plastics – thermosetting(phenol-formaldehyde, Polyurethanes) and thermosoftening (PVC, polythene);

Fabrics – natural and synthetic (acrylic, polyamido, polyester); Rubbers – natural andsynthetic: Buna-S, Chloroprene and Neoprene; Vulcanization; Polymer additives;Introduction to liquid crystal polymers; Biodegradable and conducting polymers withexamples. (12 Lectures)


1. Kalsi, P. S. Textbook of Organic Chemistry 1st Ed., New Age International (P) Ltd. Pub.2. Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.(Pearson Education).3. Billmeyer, F. W. Textbook of Polymer Science, John Wiley & Sons, Inc.4. Gowariker, V. R.; Viswanathan, N. V. & Sreedhar, J. Polymer Science, New AgeInternational (P) Ltd. Pub.5. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry ofNatural Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).6. Graham Solomons, T.W. Organic Chemistry, John Wiley & Sons, Inc.7. Clayden, J.; Greeves, N.; Warren, S.; Wothers, P.; Organic Chemistry, OxfordUniversity Press.8. Singh, J.; Ali, S.M. & Singh, J. Natural Product Chemistry, Prajati Prakashan (2010).9. Kemp, W. Organic Spectroscopy, Palgrave

Course Title Inorganic Chemistry –I V


4 0 2 6Course objectives This course discribes the theoretical principles in Qualitative Analysis,chemistry of

organometallic compounds,reaction meachanisms for the inorganic reactions.

Unit-I

Unit-II

Theoretical Principles in Qualitative Analysis (H2S Scheme)Basic principles involved in analysis of cations and anions and solubility products,common ion effect. Principles involved in separation of cations into groups and choiceof group reagents. Interfering anions (fluoride, borate, oxalate and phosphate) andneed to remove them after Group II. (10 Lectures)

Organometallic CompoundsDefinition and classification of organometallic compounds on the basis of bondtype. Concept of hapticity of organic ligands.Metal carbonyls: 18 electron rule, electroncount of mononuclear, polynuclear and substituted metal carbonyls of 3d series.General methods of preparation (direct combination, reductive carbonylation, thermaland photochemical decomposition) of mono and binuclear carbonyls of 3d series.Structures of mononuclear and binuclear carbonyls of Cr, Mn, Fe, Co and Ni using VBT.π-acceptor behaviour of CO (MO diagram of CO to be discussed), synergic effect anduse of IR data to explain extent of back bonding.

Zeise’s salt: Preparation and structure, evidences of synergic effect and comparison ofsynergic effect with that in carbonyls.

Metal Alkyls: Important structural features of methyl lithium (tetramer) and trialkylaluminium (dimer), concept of multicentre bonding in these compounds. Role of


39

Unit-III

Unit-IV

triethylaluminium in polymerisation of ethene (Ziegler – Natta Catalyst). Speciespresent in ether solution of Grignard reagent and their structures, Schlenk equilibrium.

Ferrocene: Preparation and reactions (acetylation, alkylation, metallation, MannichCondensation). Structure and aromaticity. Comparison of aromaticity and reactivitywith that of benzene. (22 Lectures)

Reaction Kinetics and MechanismIntroduction to inorganic reaction mechanisms. Substitution reactions in square planarcomplexes, Trans- effect, theories of trans effect, Mechanism of nucleophilicsubstitution in square planar complexes, Thermodynamic and Kinetic stability, Kineticsof octahedral substitution, Ligand field effects and reaction rates, Mechanism ofsubstitution in octahedral complexes. (18 Lectures)

Catalysis by Organometallic CompoundsStudy of the following industrial processes and their mechanism:

1. Alkene hydrogenation (Wilkinsons Catalyst)2. Hydroformylation (Co salts)3. Wacker Process4. Synthetic gasoline (Fischer Tropsch reaction)5. Synthesis gas by metal carbonyl complexes

(10 Lectures)

Text and References Reference Books:1. Vogel, A.I. Qualitative Inorganic Analysis, Longman, 19722. Svehla, G. Vogel's Qualitative Inorganic Analysis, 7th Edition, Prentice Hall,1996-03-07.3. Cotton, F.A. G.; Wilkinson & Gaus, P.L. Basic Inorganic Chemistry 3rd Ed.; WileyIndia.4. Huheey, J. E.; Keiter, E.A. & Keiter, R.L. Inorganic Chemistry, Principles of Structureand Reactivity 4th Ed., Harper Collins 1993, Pearson,2006.5. Sharpe, A.G. Inorganic Chemistry, 4th Indian Reprint (Pearson Education) 20056. Douglas, B. E.; McDaniel, D.H. & Alexander, J.J. Concepts and Models in InorganicChemistry3rd Ed., John Wiley and Sons, NY, 1994.6. Greenwood, N.N. & Earnshaw, A. Chemistry of the Elements, Elsevier 2nd Ed, 1997(Ziegler Natta Catalyst and Equilibria in Grignard Solution).7. Lee, J.D. Concise Inorganic Chemistry 5th Ed., John Wiley and sons 2008.8. Powell, P. Principles of Organometallic Chemistry, Chapman and Hall, 1988.9. Shriver, D.D. & P. Atkins, Inorganic Chemistry 2nd Ed., Oxford University Press, 1994.10. Basolo, F. & Person, R. Mechanisms of Inorganic Reactions: Study of MetalComplexes in Solution 2nd Ed., John Wiley & Sons Inc; NY.11. Purcell, K.F. & Kotz, J.C., Inorganic Chemistry, W.B. Saunders Co. 197712.Miessler, G. L. & Donald, A. Tarr, Inorganic Chemistry 4th Ed., Pearson, 2010.13. Collman, James P. et al. Principles and Applications of Organotransition MetalChemistry. Mill Valley, CA: University Science Books, 1987.14. Crabtree, Robert H. The Organometallic Chemistry of the Transition Metals. j NewYork, NY: John Wiley, 2000.15. Spessard, Gary O., &Gary L. Miessler. Organometallic Chemistry. Upper SaddleRiver, NJ: Prentice-Hall, 1996.

Course Title DRUGS & DYES


4 0 2 6Prerequisites --Course objectives Drugs and Dyes plays an important role in improving quality of life. Properties,

discovery and manufacturing have strong roots in chemistry and organic chemistry. This


40

course in Drugs and Dyes will help understand the characteristics of the molecules thatmake it drug like or dye like. Students will develop familiarity with the terms that areused to describe these products, the classification systems adopted based on actionand application. Last chapters on Dyes discusses methods of application of dyes tofabrics and the chemistry behind it.

Unit-I

Unit-II

DRUGSDefinition of a drug, sources of drugs, requirements of an ideal drug, classification ofdrugs (based on therapeutic action)Nomenclature of drugs: Generic name, Brand name, Systematic nameDefinition of the following medicinal terms: Pharmacon,Pharmacology,Pharmacophore, Prodrug, Half – life efficiency, LD50, ED50Brief idea of the following terms: Receptors, Agonists, Antagonists, Drug-receptorinteraction, Drug Potency, Bioavailability, Drug Toxicity.Routes of drug administration – Oral and Parenteral. Brief and broad idea ofFormulations.CNS Drugs:Classification based on pharmacological actions: CNS Depressants & CNS Stimulants.Concept of sedation and hypnosis, anaesthesia- Few examples to illustrate structureand actions: Phenytoin (Hydantoin),Trimethadione (Oxazolidinediones), Alprazolam(Benzodiazepines), Levetiracetam (Pyrrolidines), Amphetamine (Phenethylamine),Chlorpromazine (Phenothiazines).Analgesics and Antipyretics – ExamplesMorphine (Phenanthrene alkaloids), Tramadol (Cyclohexanols), Aspirin (Salicylates),Paracetamol (p-Amino phenols)Anti-inflammatory Drugs with examplesSteroids: Betamethasone, Sodium Diclofenac, Aceclofenac (N- Aryl anthranilic acids),Cetrizene (Piperazine), Chlorpheniramine maleate (Ethyl amines), Pantoprazole(Benzimidazoles)Cardiovascular drugs – Generic structuresClassification based on pharmacological actionIsosorbide dinitrate (Nitrates), Valsartan (Amino acids) (structure not expected),Atenolol (Aryloxy propanol amines), Amlodipine (Pyridines), Frusemide /Furosemide(Sulfamoyl benzoic acid), Rosuvastatin (Pyrimidine)Antidiabetic AgentsGeneral idea and types of diabetes with few examples from below:Glibenclamide (Sulphonyl ureas), Metformin (Biguanides), Dapagliflozin (Pyranose),Pioglitazone (Thiazolidinediones)Drugs for Respiratory SystemGeneral idea of: Expectorants; Mucolytes; Bronchodilators, Decongestants; Antitussiveswith few examples: Ambroxol (Cyclohexanol), Salbutamol (Phenyl ethyl amines),Oxymetazoline (Imidazolines) (30 Lectures)

DYES

Introduction to the dye-stuff IndustryDefinition of dyes, requirements of a good dye i.e. Colour,Chromophore andAuxochrome, Solubility, Linearity, Coplanarity, Fastness, Substantivity, Economicviability.Definition of fastness and its properties and Mordants with examples,Explanation of nomenclature or abbreviations of commercial dyes with few examplesNatural and Synthetic DyesNatural Dyes: Definition and limitations of natural dyes.Examples and uses of natural dyes w.r.t Indigo, Turmeric, Saffron, (structure notexpected)Synthetic dyes: Definition of synthetic dyes, primaries and intermediates. Important


41

milestones in the development of synthetic dyes– Emphasis on Name of the Scientist,dyes and the significance of the discovery (structure is not expected)Substrates for Dyes: Types of fibresNatural: cellulosic and proteinaceous fibres, examples – of dyes applied on them.Synthetic: Example of Nylon, structures and names of dyes applied on it.Binding forces of dyes on substrate: ionic forces, covalent linkages, hydrogen bonding,Van der-waals forcesClassification of dyes based on applicability on substrates (examples with structures)(a) Acid Dyes, (b) Basic Dyes, (c) Direct cotton Dyes, (d) Azoic Dyes(e) Mordant Dyes, (f) Vat Dyes, (g) Sulphur Dyes, (h) Disperse Dye(i) Reactive DyesClassification of dyes based on applications and dyeing methods – General methods-Basic Operations involved in dyeing process; Dyeing method of cotton fibresa) Direct b) Vat c) Mordant d) Disperse (30 Lectures)

Course outcomes After studying this topic, students are expected to know:Definition of drug, classification of drugs based on therapeutic action, requirement ofan ideal drug. Definition of terms related to drugs and its action – Drug receptor,Agonist, Antagonist, Pharmocophore, Prodrug, Toxicity terms etc. Classification of drugsbased on pharmacological actions. Different Pharmacodynamic agents as listed in thesyllabus, its structural features with select synthesis of few drugs. General idea of actionof the different pharmacodynamic agents. The structural aspects and thepharmacophores that produces drug like action and its similarity. How changes instructural features determine enhanced activity. Not required to memorize thestructures but understand the features that make a product drug like. Learn thetherapeutic class with few examples’ drugs related to CNS, Anti-inflammatory,Anti-pyretics, Analgesic, Antihistaminic, Antidiabetic, Cardiovascular and drugs forrespiratory diseases. Definition of dyes, chromophore, auxochrome and related terms,nomenclature of commercial dyes. Relation between colour and chemical constitution.Definition of natural dyes, its limitations, definition of synthetic dyes and its history.Substrates for dyes-natural and synthetic, the binding actions on the substrates.Classification of dyes based on applicability on substrates with examples -structuralfeatures important. Classification of dyes based on applications and dyeing methods.

Text and References Reference Books:1.Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd.(Pearson Education)2. A text book of organic Chemistry by Arun Bahl and B S Bahl S. Chand publication3. Chemistry of Synthetic Dyes, Vol I – VIII, Venkatraman K., Academic Press 19724. The Chemistry of Synthetic Dyes and Pigments, Lubs H.A., Robert E KriegerPublishing Company, NY ,19955. Chemistry of Dyes and Principles of Dyeing, Shenai V.A., Sevak Publications, 19736. Text book of organic medicinal & pharmaceutical chemistry. Wilson &Gisovolds, 11thEdition by John H Block, John M Beale Jr.7. Medicinal chemistry. Ashutosh Kar, New Age International Pvt. Ltd Publisher. 4thedition.8. Medicinal chemistry. V.K. Ahluwalia and Madhu Chopra, CRC Press.9. The organic chemistry of drug design & drug action. 2nd ed. By Richard B Silvermann,Academic Press.


42

Course Title Applications of Computers in Chemistry


4 0 2 6Course objectives This Course provides the knowledge of utilization of computers in field of

chemistry.Chemistry and chemical engineering, like many other disciplines, are beingprofoundly influenced by increased computing power.The small applications developedin programming aims to produce results for given values of constants and for observedvalues of inputs for various experiments from curriculum.

Unit-I

Unit-II

Basics and MS office:MS office :-Excel, Word and Power pointConstants, variables, bits, bytes, binary and ASCII formats, arithmetic expressions,hierarchy of operations, inbuilt functions. Elements of the BASIC language. BASICkeywords and commands. Logical and relative operators. Strings and graphics.Compiled versus interpreted languages. Debugging. Simple programs using theseconcepts. Matrix addition and multiplication. Statistical analysis. (30 Lectures)

Numerical methods:Roots of equations: Numerical methods for roots of equations: Quadratic formula,iterative method, Newton-Raphson method, Binary bisection and Regula-Falsi.Differential calculus: Numerical differentiation.Integral calculus: Numerical integration (Trapezoidal and Simpson’s rule), probability

distributions and mean values.

Simultaneous equations: Matrix manipulation: addition, multiplication. Gauss-Siedalmethod.Interpolation, extrapolation and curve fitting: Handling of experimental data.Conceptual background of molecular modelling: Potential energy surfaces. Elementary

ideas of molecular mechanics and practical MO methods. (30 Lectures)

Text and References Reference Books:1. Harris, D. C. Quantitative Chemical Analysis. 6th Ed., Freeman (2007) Chapters 3-5.2. Levie, R. de, How to use Excel in analytical chemistry and in general scientific dataanalysis, Cambridge Univ. Press (2001) 487 pages.3. Noggle, J. H. Physical chemistry on a Microcomputer. Little Brown & Co. (1985).4. Venit, S.M. Programming in BASIC: Problem solving with structure andstyle.Jaico Publishing House: Delhi (1996).

Course Title ANALYTICAL CHEMISTRYCourse Code BSCM605Course Credits L T P Credits

4 0 2 6Course objectives The course deals with the basic analytical methods and offers sound knowledge of

chemistry involved in an analysis and to understand the concept of analyticaltechniques. In the beginning of the course it discusses the Qualitative and quantitativeaspects of analysis . It also describes the Optical methods ,thermal and electrochemicalmethod of analysis,seperation techniques I.e.extraction and chromatography.

Unit-I Qualitative and quantitative aspects of analysis:Sampling, evaluation of analytical data, errors, accuracy and precision, methods of theirexpression, normal law of distribution if indeterminate errors, statistical test of data; F,Q and t test, rejection of data, and confidence intervals. (5 Lectures)


43

Unit-II

Unit-III

Unit-IV

Unit-V

Optical methods of analysis:Origin of spectra, interaction of radiation with matter, fundamental laws ofspectroscopy and selection rules, validity of Beer-Lambert’s law.UV-Visible Spectrometry: Basic principles of instrumentation (choice of source,monochromator and detector) for single and double beam instrument;Basic principles of quantitative analysis: estimation of metal ions from aqueoussolution, geometrical isomers, keto-enol tautomers. Determination of composition ofmetal complexes using Job’s method of continuous variation and mole ratio method.Infrared Spectrometry: Basic principles of instrumentation (choice of source,monochromator & detector) for single and double beam instrument; samplingtechniques.Structural illustration through interpretation of data, Effect and importance of isotopesubstitution.Flame Atomic Absorption and Emission Spectrometry: Basic principles ofinstrumentation (choice of source, monochromator, detector, choice of flame andBurner designs. Techniques of atomization and sample introduction; Method ofbackground correction, sources of chemical interferences and their method of removal.Techniques for the quantitative estimation of trace level of metal ions from watersamples . (25 Lectures)

Thermal methods of analysis:Theory of thermogravimetry (TG), basic principle of instrumentation.Techniques for quantitative estimation of Ca and Mg from their mixture. (5 Lectures)

Electroanalytical methods:Classification of electroanalytical methods, basic principle of pH metric, potentiometricand conductometric titrations. Techniques used for the determination of equivalencepoints. Techniques used for the determination of pKa values. (10 Lectures)

Separation techniques:Solvent extraction: Classification, principle and efficiency of the technique.Mechanism of extraction: extraction by solvation and chelation.Technique of extraction: batch, continuous and counter current extractions.Qualitative and quantitative aspects of solvent extraction: extraction of metal ions fromaqueous solution, extraction of organic species from the aqueous and nonaqueousmedia.Chromatography: Classification, principle and efficiency of the technique.Mechanism of separation: adsorption, partition & ion exchange.Development of chromatograms: frontal, elution and displacementmethods.Qualitative and quantitative aspects of chromatographic methods of analysis:IC, GLC, GPC, TLC and HPLC.Stereoisomeric separation and analysis: Measurement of optical rotation, calculation ofEnantiomeric excess (ee)/ diastereomeric excess (de) ratios and determination ofenantiomeric composition using NMR, Chiral solvents and chiral shift reagents.Chiralchromatographic techniques using chiral columns (GC and HPLC).Role ofcomputers in instrumental methods of analysis. (15 Lectures)


1. Vogel, Arthur I: A Test book of Quantitative Inorganic Analysis (Rev. by G.H. Jefferyand others) 5th Ed. The English Language Book Society of Longman .2. Willard, Hobert H. et al.: Instrumental Methods of Analysis, 7th Ed. WardsworthPublishing Company, Belmont, California, USA, 1988.3. Christian, Gary D; Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.4. Harris, Daniel C: Exploring Chemical Analysis, Ed. New York, W.H. Freeman, 2001.


44

5. Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age, InternationalPublisher, 2009.6. Skoog, D.A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, ThomsonAsia Pvt. Ltd. Singapore.7. Mikes, O. & Chalmes, R.A. Laboratory Hand Book of Chromatographic & AlliedMethods, Elles Harwood Ltd. London.8. Ditts, R.V. Analytical Chemistry – Methods of separation.

Course Title INSTRUMENTAL METHODS OF CHEMICAL ANALYSIS


4 0 2 6Prerequisites Student should have required knoledge of general chemistry,physics and selected

topics of mathematics and statistics.Course objectives This course concerns the theory and practice of instrumental methods for the

seperation,identification and quantitative analysis of chemical substances.Itunderstands to apply the theory and operational principles of analyticalinstruments.Overview of spectroscopic techniques like on IR,NMR and UV is explainedin brief.

Unit-I

Unit-II

Unit-III

Introduction to spectroscopic methods of analysis:Recap of the spectroscopic methods covered in detail in the core chemistry syllabus:Treatment of analytical data, including error analysis. Classification of analyticalmethods and the types of instrumental methods. Consideration of electromagneticradiation. (4 Lectures)

Molecular spectroscopy:Infrared spectroscopy:Interactions with molecules: absorption and scattering. Means ofexcitation (light sources), separation of spectrum (wavelength dispersion, timeresolution), detection of the signal (heat, differential detection), interpretation ofspectrum (qualitative, mixtures, resolution), advantages of Fourier Transform (FTIR).Samples and results expected. Applications: Issues of quality assurance and qualitycontrol, Special problems for portable instrumentation and rapid detection.

UV-Visible/ Near IR – emission, absorption, fluorescence and photoaccoustic. Excitationsources (lasers, time resolution), wavelength dispersion (gratings, prisms, interferencefilters, laser, placement of sample relative to dispersion, resolution), Detection of signal(photocells, photomultipliers, diode arrays, sensitivity and S/N), Single and DoubleBeam instruments, Interpretation (quantification, mixtures, absorption vs. fluorescenceand the use of time, photoaccoustic, fluorescent tags). (16 Lectures)

Separation techniquesChromatography: Gas chromatography, liquid chromatography, supercritical fluids,Importance of column technology (packing, capillaries), Separation based on increasingnumber of factors (volatility, solubility, interactions with stationary phase, size,electrical field), Detection: simple vs. specific (gas and liquid), Detection as a means offurther analysis (use of tags and coupling to IR and MS), Electrophoresis (plates andcapillary) and use with DNA analysis. Immunoassays and DNA techniques

Mass spectroscopy: Making the gaseous molecule into an ion (electron impact,chemical ionization), Making liquids and solids into ions (electrospray, electricaldischarge, laser desorption, fast atom bombardment), Separation of ions on basis ofmass to charge ratio, Magnetic, Time of flight, Electric quadrupole. Resolution, timeand multiple separations, Detection and interpretation (how this is linked to


45

Unit-IV

Unit-V

Unit-VI

Unit-VII

Unit-VIII

excitation). (16 Lectures)

Elemental analysis:Mass spectrometry (electrical discharges).Atomic spectroscopy: Atomic absorption, Atomic emission, and Atomic fluorescence.Excitation and getting sample into gas phase (flames, electrical discharges, plasmas),Wavelength separation and resolution (dependence on technique), Detection ofradiation (simultaneous/scanning, signal noise), Interpretation (errors due to molecularand ionic species, matrix effects, other interferences). (8 Lectures)

NMR spectroscopy: Principle, Instrumentation, Factors affecting chemical shift,Spin-coupling, Applications. (4Lectures)

Electroanalytical Methods: Potentiometry & Voltammetry (4 Lectures)

Radiochemical Methods (4 Lectures)

X-ray analysis and electron spectroscopy (surface analysis) (4 Lectures)


1. Instrumental Methods of Analysis, 7th ed, Willard, Merritt, Dean, Settle.2. P.W. Atkins: Physical Chemistry.3. G.W. Castellan: Physical Chemistry.4. C.N. Banwell: Fundamentals of Molecular Spectroscopy.5. Brian Smith: Infrared Spectral Interpretations: A Systematic Approach.6. W.J. Moore: Physical Chemistry.


46

CHEMISTRY PRACTICAL SYLLABUS

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Semester I

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CHEMISTRY LAB- C I LAB:

(A) Titrimetric Analysis(i)Cleaning of apparatus(ii) Calibration and use of apparatus(iii) Preparation of solutions of different Molarity/Normality of titrants(iv) Determination of Hardness by EDTA method

(B) Acid-Base Titrations(i) Simple acidimetry-Alkalimetry (12)(ii) Estimation of carbonate and bicarbonate present together in a mixture(iii) Estimation of carbonate and hydroxide present together in mixture

(C) Oxidation-Reduction Titrimetry(i) Estimation of Fe(II) and oxalic acid using standardized KMnO4 solution.(ii) Estimation of Fe(II) with K2Cr2O7 using internal (diphenylamine, anthranilic acid) and external indicator(iii) Estimation of H2SO4 and H2C2O4 per litre of solution.

Any other experiment carried out in the class.

Reference text:

1. Vogel, A.I. A Textbook of Quantitative Inorganic Analysis, ELBS.

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CHEMISTRY LAB-C II LAB

Physical Chemistry

1. Surface tension measurements.a. Determine the surface tension by (i) drop number (ii) drop weight method.(8)b. Study the variation of surface tension of detergent solutions with concentration.

2. Viscosity measurement using Ostwald’s viscometer.a. Determination of viscosity of various organic liquids at room temperature.b. Study the variation of viscosity of sucrose solution with the concentration of solute.

3. pH metry.a. Preparation of buffer solutions of different pH

(i) Sodium acetate-acetic acid(ii) Ammonium chloride-ammonium hydroxide


Reference Books

1. Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand & Co.: New Delhi (2011).2. Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8th Ed.; McGraw-Hill: New York(2003).3. Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3rd Ed.;W.H. Freeman & Co.: New York (2003).

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Semester II

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CHEMISTRY LAB-C III LAB

Organic Chemistry

1. Spotting of mono-functional Organic Compounds via elemental analysis and functional group analysis (16)

2. Purification of organic compounds by crystallization using the following solvents:a) Waterb) Alcoholc) Alcohol-Water

3. Determination of boiling point of liquid compounds. (boiling point lower than and more than 100 °C by distillationand capillary method)

References Books

1. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)2. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed., Pearson(2012)

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CHEMISTRY LAB- C IV LAB

Physicalchemistry(a) pH metric titration of

(i) strong acid vs. strong base(ii) weak acid vs. strong base

(b) Perform the following conductometric titrations:(i) Strong acid vs. Strong base(ii) strong acid vs. Weak base

(c) To study the effect of rate of reaction

(d) Surfactant and colloidal based experiments.


Reference Books

1. Khosla, B. D.; Garg, V. C. & Gulati, A., Senior Practical Physical Chemistry, R. Chand & Co.: New Delhi (2011).2. Athawale, V. D. & Mathur, P. Experimental Physical Chemistry New Age International: New Delhi (2001).---------------------------------------------------------------------------------------------------------------------------------------------------

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Semester III

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CHEMISTRY LAB-C V LAB

(A) Inorganic Chemistry(a) Qualitative semi-micro analysis of subtance containing one cation and one anion(12)(b) Complexometry titrations(3)(c) Idometric titration

Reference Books:

1. Vogel, A.I. A Textbook of Quantitative Inorganic Analysis, ELBS. 1978---------------------------------------------------------------------------------------------------------------------------------------------------

CHEMISTRY LAB- C VI LAB

(B) Organic Chemistry(i) Spotting of bi-functional Organic Compounds via elemental analysis and functional group analysis (14)(ii) Organic Preparations:

1. Bromination of any one of the following:(a) Acetanilide by conventional methods(b) Acetanilide using green approach (Bromate-bromide method)

2. Nitration of any one of the following:(a) Acetanilide/nitrobenzene by conventional method

Reference Books

1. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)2. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed., Pearson (2012)3. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry: Preparation and Quantitative Analysis,University Press (2000).4. Ahluwalia, V.K. & Dhingra, S. Comprehensive Practical Organic Chemistry: Qualitative Analysis, University Press(2000).---------------------------------------------------------------------------------------------------------------------------------------------------

CHEMISTRY PRACTICAL-C VII LAB

(C) Physical Chemistry(i) Chemical kinetics (4)

(ii) Phase equilibria: Construction of the phase diagram using cooling curves or ignition tube method:a). simple eutectic andb). congruently melting systems.

(iii) Distribution of acetic/ benzoic acid between water and cyclohexane.

(iv) Adsorption (2)

a). Verify the Freundlich and Langmuir isotherms for adsorption of acetic acid on activatedcharcoal.


Reference Books:

1. Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand & Co.: New Delhi (2011).


49

2. Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8th Ed.; McGraw-Hill: New York(2003).3. Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3rd Ed.;W.H. Freeman & Co.: New York (2003).---------------------------------------------------------------------------------------------------------------------------------------------------

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Semester IV

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CHEMISTRY-C VIII LAB

(A) Inorganic Chemistry

Gravimetric Analysis:i. Estimation of nickel (II) using Dimethylglyoxime (DMG).ii. Estimation of copper as CuSCNiii. Estimation of iron as Fe2O3 by precipitating iron as Fe(OH)3.iv. Estimation of Al (III) by precipitating with oxine and weighing as Al(oxine)3 (aluminium oxinate).

Inorganic Preparations:i. Cuprous Oxide, Cu2oii. Preparation of Ferrous Ammonium Sulfateiii. Preparation of Aluminium potassium sulphate KAl(SO4)2.12H2O (Potash alum) or Chrome alum.iv. Qualitative semi-micro analysis of subtance containing two cations and two anions(8)

Reference Book:

1. Vogel, A.I. A text book of Quantitative Analysis, ELBS 1986.

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CHEMISTRY PRACTICAL-C IX LAB

(B) Organic Chemistryi. Organic Analysis (8)ii. Chromatographic sepeartion technique: Thin layer Chromatography (4)

Reference Books

1. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)2. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed., Pearson (2012)3. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry: Preparation and Quantitative Analysis,University Press (2000).4. Ahluwalia, V.K. & Dhingra, S. Comprehensive Practical Organic Chemistry: Qualitative Analysis, University Press(2000).

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CHEMISTRY PRACTICAL-C X LAB

(C) Physical Chemistry

Conductometry


50

Perform the following conductometric titrations:i. Weak acid vs. strong baseii. Mixture of strong acid and weak acid vs. strong base

PotentiometryPerform the following potentiometric titrations:

i. Strong acid vs. strong baseii. Weak acid vs. strong base

pHmetrya. Study the effect on pH of addition of HCl/NaOH to solutions of acetic acid, sodium acetate and their

mixtures.1. Determination of dissociation constant of a weak acid.

Colourimetry (2)


Reference Books:

1. Khosla, B. D.; Garg, V. C. & Gulati, A. Senior Practical Physical Chemistry, R. Chand & Co.: New Delhi (2011).2. Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8th Ed.; McGraw-Hill: New York(2003).3. Halpern, A. M. & McBane, G. C. Experimental Physical Chemistry 3rd Ed.;W.H. Freeman & Co.: New York (2003).

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Semester V

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CHEMISTRY PRACTICAL-C XI LAB

Organic Chemistry1. Study of the action of salivary amylase on starch at optimum conditions.2. Effect of temperature on the action of salivary amylase.3. Saponification value of an oil or a fat.4. Isolation and characterization of DNA from onion/ cauliflower/peas/bananas.5. Synthesis of drugs.6. Preparation of polymers.

Reference Books:

1. Manual of Biochemistry Workshop, 2012, Deptt of Chemistry, University of Delhi.2. Arthur, I. V. Quantitative Organic Analysis, Pearson.---------------------------------------------------------------------------------------------------------------------------------------------------

CHEMISTRY PRACTICAL-C XII LAB

Physical Chemistry

UV/Visible spectroscopyi. Study the 200-500 nm absorbance spectra of KMnO4 and K2Cr2O7 (in 0.1 M H2SO4) and determine the λ max

values. Calculate the energies of the two transitions in different units (J molecule-1, kJ mol-1, cm-1, eV).


51

ii. Study the pH-dependence of the UV-Vis spectrum (200-500 nm) of K2Cr2O7.iii. Record the 200-350 nm UV spectra of the given compounds (acetone, acetaldehyde, 2-propanol, acetic acid) in

water. Comment on the effect of structure on the UV spectra of organic compounds.

Extraction Based Experiments

Water Analysis


Reference Books

1. Khosla, B. D.; Garg, V. C. & Gulati, A., Senior Practical Physical Chemistry, R. Chand & Co.: New Delhi (2011).2. Garland, C. W.; Nibler, J. W. & Shoemaker, D. P. Experiments in Physical Chemistry 8th Ed.; McGraw-Hill: New York(2003).

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Semester VI

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CHEMISTRY PRACTICAL-C XIII LAB

(A) Inorganic Chemistryi. Qualitative semimicro analysis of mixtures containing 3 anions and 3 cations. Emphasis should be given to the

understanding of the chemistry of different reactions. (10)ii. Complex Preparation(4)iii. Bleaching Powder Analysis

Mixtures should preferably contain one interfering anion, or insoluble component (BaSO4, SrSO4, PbSO4, CaF2 orAl2O3)or combination of anions e.g. CO3

2-and SO32-, NO2

- and NO3-, Cl- and Br-, Cl- and I-, Br-and I-, NO3

- and Br-, NO3- and

I-.

Reference Books

1. Vogel’s Qualitative Inorganic Analysis, Revised by G. Svehla.2. Marr & Rockett Inorganic Preparations.---------------------------------------------------------------------------------------------------------------------------------------------------

CHEMISTRY PRACTICAL-C XIV LAB

(B) Organic Chemistry1. Synthesis of Dyes2. Spotting of three-functional Organic Compounds via elemental analysis and functional group analysis3. Argentometric titration4. Benzoylation


Reference Books:

1. Vogel, A.I. Quantitative Organic Analysis, Part 3, Pearson (2012).2. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education (2009)3. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed., Pearson (2012)


52

4. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry: Preparation and Quantitative Analysis,University Press (2000).5. Ahluwalia, V.K. & Dhingra, S. Comprehensive Practical Organic Chemistry: Qualitative Analysis, University Press(2000).

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DISCIPLINE ELECTIVE- PRACTICAL SYLLABUS

APPLICATIONS OF COMPUTERS IN CHEMISTRY

1. Computer programs based on numerical methods for Roots of equations: (e.g. volume of van der Waals gas andcomparison with ideal gas, pH of a weak acid).

2. Numerical differentiation (e.g., change in pressure for small change in volume of a van der Waals gas,potentiometric titrations).

3. Numerical integration (e.g. entropy/ enthalpy change from heat capacity data), probability distributions (gas kinetictheory) and mean values.

4. Matrix operations. Application of Gauss-Siedel method in colourimetry.

5. Simple exercises using molecular visualization software.

Reference Books:

1. McQuarrie, D. A. Mathematics for Physical Chemistry University Science Books (2008).

2. Mortimer, R. Mathematics for Physical Chemistry. 3rd Ed. Elsevier (2005).

3. Steiner, E. The Chemical Maths Book Oxford University Press (1996).

4. Yates, P. Chemical Calculations. 2nd Ed. CRC Press (2007).

5. Harris, D. C. Quantitative Chemical Analysis. 6th Ed., Freeman (2007) Chapters 3-5.

6. Levie, R. de, How to use Excel in analytical chemistry and in general scientific data analysis, Cambridge Univ. Press(2001) 487 pages.

7. Noggle, J. H. Physical Chemistry on a Microcomputer. Little Brown & Co. (1985).

8. Venit, S.M. Programming in BASIC: Problem solving with structure and style. Jaico Publishing House: Delhi(1996).

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ANALYTICAL METHODS IN CHEMISTRY

I. Separation Techniques1. Chromatography:

(a) Separation of mixtures(i) Paper chromatographic separation of Fe3+, Al3+, and Cr3+.


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II.Solvent Extractions:1. To separate a mixture of Ni2+ & Fe2+ by complexation with DMG and extracting the Ni2+-DMGcomplex in chloroform, and determine its concentration by spectrophotometry.

2. Solvent extraction of zisconium with amberliti LA-1, separation from a mixture of irons and gallium.3. Determine the pH of the given aerated drinks fruit juices, shampoos and soaps.4. Determination of Na, Ca, Li in cola drinks and fruit juices using fame photometric techniques.5. Analysis of soil:

(i) Determination of pH of soil.(ii) Total soluble salt(iii) Estimation of calcium, magnesium, phosphate, nitrate

III. Spectrophotometry1. Determination of pKa values of indicator using spectrophotometry.2. Structural characterization of compounds by infrared spectroscopy.3. Determination of dissolved oxygen in water.4. Determination of chemical oxygen demand (COD).5. Determination of Biological oxygen demand (BOD).6. Determine the composition of the Ferric-salicylate/ ferric-thiocyanate complex by Job’s method.

Reference Books

1. Vogel, Arthur I: A Test book of Quantitative Inorganic Analysis (Rev. by G.H. Jeffery and others) 5th Ed. The EnglishLanguage Book Society of Longman .

2. Willard, Hobert H. et al.: Instrumental Methods of Analysis, 7th Ed. Wardsworth Publishing Company, Belmont,California, USA, 1988.

3. Christian, Gary D; Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.

4. Harris, Daniel C: Exploring Chemical Analysis, Ed. New York, W.H. Freeman, 2001.

5. Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age, International Publisher, 2009.

6. Skoog, D.A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Thomson Asia Pvt. Ltd. Singapore.

7. Mikes, O. & Chalmes, R.A. Laboratory Hand Book of Chromatographic & Allied Methods, Elles Harwood Ltd. London.

8. Ditts, R.V. Analytical Chemistry – Methods of separation.

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NOVEL INORGANIC SOLIDS

1. Determination of cation exchange method2. Determination of total difference of solids.3. Synthesis of hydrogel by co-precipitation method.4. Synthesis of silver and gold metal nanoparticles.

Reference Book:


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1. Fahan,Materials Chemistry, Springer (2004).

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POLYMER CHEMISTRY

1. Polymer synthesis1. Preparation of nylon 66/62. Redox polymerization of acrylamide3. Precipitation polymerization of acrylonitrile4. Preparation of urea-formaldehyde resin5. Preparations of novalac resin/resold resin.6. Microscale Emulsion Polymerization of Poly(methylacrylate).

Polymer characterization

1. Determination of molecular weight by viscometry:(a) Polyacrylamide-aq.NaNO2 solution(b) (Poly vinyl proplylidine (PVP) in water

2. Determination of the viscosity-average molecular weight of poly(vinyl alcohol) (PVOH) and the fraction of“head-to-head” monomer linkages in the polymer.

3. Determination of molecular weight by end group analysis: Polyethylene glycol (PEG) (OH group).4. Testing of mechanical properties of polymers.5. Determination of hydroxyl number of a polymer using colorimetric method.

Polymer analysis1. Estimation of the amount of HCHO in the given solution by sodium sulphite method2. Instrumental Techniques3. IR studies of polymers4. DSC analysis of polymers5. Preparation of polyacrylamide and its electrophoresis

*at least 7 experiments to be carried out.

Reference Books:

1. Malcohm P. Stevens, Polymer Chemistry: An Introduction, 3rd Ed.2. Harry R. Allcock, Frederick W. Lampe and James E. Mark, Contemporary Polymer Chemistry, 3rd ed. Prentice-Hall(2003)3. Fred W. Billmeyer, Textbook of Polymer Science, 3rd ed. Wiley-Interscience (1984)4. Joel R. Fried, Polymer Science and Technology, 2nd ed. Prentice-Hall (2003)---------------------------------------------------------------------------------------------------------------------------------------------------

GREEN CHEMISTRY

I. Organic preparations by green chemistry using Microwave

II. Photochemical based Synthesis

Reference Books:

1. Anastas, P.T & Warner, J.C. Green Chemistry: Theory and Practice, Oxford University Press (1998).


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2. Kirchoff, M. & Ryan, M.A. Greener approaches to undergraduate chemistry experiment. American Chemical Society,Washington DC (2002).

3. Ryan, M.A. Introduction to Green Chemistry, Tinnesand; (Ed), American Chemical Society, Washington DC (2002).

4. Sharma, R.K.; Sidhwani, I.T. & Chaudhari, M.K. I.K. Green Chemistry Experiment: A monograph InternationalPublishing House Pvt Ltd. New Delhi. Bangalore CISBN 978-93-81141-55-7 (2013).

5. Cann, M.C. & Connelly, M. E. Real world cases in Green Chemistry, American Chemical Society (2008).

6. Cann, M. C. & Thomas, P. Real world cases in Green Chemistry, American Chemical Society (2008).

7. Pavia, D. L. Lamponan, G. H. &Kriz, G.S.W B Introduction to organic laboratory

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INDUSTRIAL CHEMICALS & ENVIRONMENT

1. Determination of dissolved oxygen in water.2. Determination of Chemical Oxygen Demand (COD)3. Determination of Biological Oxygen Demand (BOD)4. Percentage of available chlorine in bleaching powder.5. Measurement of chloride, sulphate and salinity of water samples by simple titration method (AgNO3and potassium chromate).6. Estimation of total alkalinity of water samples (CO3

2-, HCO3-) using double titration method.

7. Measurement of dissolved CO2.8. Study of some of the common bio-indicators of pollution.9. Preparation of borax/ boric acid.

Reference Books:

1. E. Stocchi: Industrial Chemistry, Vol-I, Ellis Horwood Ltd. UK.

2. R.M. Felder, R.W. Rousseau: Elementary Principles of Chemical Processes, Wiley Publishers, New Delhi.

3. J. A. Kent: Riegel’s Handbook of Industrial Chemistry, CBS Publishers, New Delhi.

4. S. S. Dara: A Textbook of Engineering Chemistry, S. Chand & Company Ltd. New Delhi.

5. K. De, Environmental Chemistry: New Age International Pvt., Ltd, New Delhi.

6. S. M. Khopkar, Environmental Pollution Analysis: Wiley Eastern Ltd, New Delhi.

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INSTRUMENTAL METHODS OF CHEMICAL ANALYSIS

1. Safety Practices in the Chemistry Laboratory2. Determination of the isoelectric pH of a protein.3. Potentiometric Titration of a Chloride-Iodide Mixture4. Nuclear Magnetic Resonance5. Detection of pollutants or illegal dumping

Reference Books:


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1. Principles of Instrumental Analysis - 6th Edition by Douglas A. Skoog, F. James Holler, and Stanley Crouch(ISBN 0-495-01201-7).2. Instrumental Methods of Analysis, 7th ed, Willard, Merritt, Dean, Settle.

GENERIC ELECTIVE- PHYSICS PRACTICALS

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Semester I

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1. Error Analysis-I: (i) Uncertainties and error propagation. (ii) use of significant figures in the propagation ofuncertainty. (iii) Plotting of graph and curve fitting.

2. Error Analysis-II: (i) Combining and reporting uncertainties in measurements. (ii) Estimation of the uncertainty inan averaged measurement.

3. Young’s Modulus of metal bar: To determine the young’s modulus of elasticity of given material.4. Young’s Modulus of a wire: To determine the young’s modulus of elasticity of given material.5. Bar-Pendulum- Measurement of value of acceleration due to gravity ‘g’.6. Moment of Inertia: Determination of the moment of inertia of an irregular body about an axis passing through its

centre of gravity and perpendicular to its plane.7. Torsional Pendulum: To determine the moment of inertia of the given disc using torsion pendulum, with identical

masses.8. Free Vibration of spring mass system in Virtual lab: To obtain the natural frequency of the spring-mass system and

observe its response to an initial disturbance and the type of the system based on damping ratio.-----------------------------------------------------------------------------------------------------

Semester II

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1. Vibration magnetometer: Determination of the ratio of magnetic moment of the given bar magnets.2. Deflection magnetometer: Determination of the magnetic moment of a given magnet using magnetometer at

Gauss A and Gauss B position.3. Magnetic effect of current: (i) To study the variation of magnetic field with distance along the axis of a circular coil

carrying current by plotting a graph. (ii) Determination of the radius of the coil using given laboratory setup.4. Introduction to CRO/DSO: (i)To understand the functions of CRO/DSO. (ii)Measure frequency of AC signal and AC

& DC voltage.5. Hysteresis loss: To calculate Retentivity, Coercivity and Saturation Magnetization by studying hysteresis loop for a

given ferromagnetic material.6. Charging and discharging of capacitor: To determine the capacitance of a capacitor by studying the variation

during its charging and discharging.7. Temperature coefficient of resistance: To find the TCR of a given coil.8. Barkhausen effect in Virtual lab: To understand the barkhausen effect on ferromagnetic material.

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Semester III

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1. Stefan-Boltzmann’s law : To verify Stefan-Boltzmann law of thermal radiation by electrical method.2. Determination of Planck constant.3. Photoelectric effect: (i) To find the value of Planck’s constant and photoelectric work function of the

material of the cathode using a photo-electric cell. (i) To verify the inverse square law of radiation using aphoto-voltaic cell.


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4. Newton’s law of cooling: Study the relationship between the temperature of a hot body and time byplotting a cooling curve.

5 Heat capacities of gases: Determine the molar heat capacities of air at constant volume Cv and atconstant pressure Cp.

6. To determine the Coefficient of Thermal Conductivity of Copper by Searle’s Method.7. Heat Transfer by Radiation in Virtual lab: (i) To compare heat transfer between different material surface

and the black body surface by radiation. (ii) To find the emissivity of different material surfaceThermo-couple Seebeck effect in Virtual lab: To verify the relation between thermo emf of a thermocouple andtemperature difference between two hot junctions.

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Semester IV

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1. Sonometer: Determination of frequency of A.C. Mains using Sonometer.2. Melde’s Experiment: Determine the frequency of an electrically maintained tuning fork by transverse and

longitudinal mode of vibration.3. Spectrometry: (i) Determination of angle of Prism. (ii) Determination of refractive index of prism using

spectrometer.4. Michelson interferometer: To determine the wavelength of a light using the Michelson interferometer.5. Newton’s ring: To determine the wavelength of source light and radius of curvature of the given convex

lens by measuring the diameters of Newton’s rings.6. Diffraction Grating- Determination of wavelength of given light source using spectrometer diffraction

grating.7. Abbe’s Refractometer in Virtual lab: To find the refractive index of the given liquid samples.

a) To study the variation of refractive index withb) temperature of the liquid sample.c) wavelength of the light source.d) To determine the polarisability of the given liquid samples at a given temperature.

8. Brewster’s Angle determination in Virtual lab: To verify the Brewster's law and to find the Brewster'sangle.

Reference Books1. B.Sc. Physics practical, Agrawal, Jain & Sharma,Krishna Publishing House, 20142. B.Sc. Physics Practical, C L Arora, S.Chand Publishing House 20103. B.Sc. Physics Practical, S.Harnam, P.S. Hemne, S.Chand 2002

GENERIC ELECTIVE- BIOTECHNOLOGY PRACTICAL

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Semester I

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1. To study activity of any enzyme under optimum conditions.2. To study the effect of pH, temperature on the activity of salivary amylase enzyme.


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3. Determination of - pH optima, temperature optima, Km value, Vmax value, Effect of inhibitor (Inorganicphosphate) on the enzyme activity.4. Estimation of blood glucose by glucose oxidase method.5. Principles of Colorimetry: (i) Verification of Beer's law, estimation of protein. (ii) To study relation

between absorbance and % transmission.6. Preparation of buffers.7. Separation of Amino acids by paper chromatography.8. Qualitative tests for Carbohydrates, lipids and proteins

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Semester II

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1. Perform of ethanolic fermentaion using Baker’s yeast2. Study of a plant part infected with a microbe3. To perform quantitative estimation of residual chlorine in water samples4. Isolation and analysis of DNA from minimal available biological samples5. Case studies on Bioethics (any two)

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Semester III

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1. Proxy filing of Indian Product patent2. Proxy filing of Indian Process patent3. Planning of establishing a hypothetical biotechnology industry in India4. A case study on clinical trials of drugs in India with emphasis on ethical issues.5. Case study on women health ethics.6. Case study on medical errors and negligence.7. Case study on handling and disposal of radioactive waste

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Semester IV

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Project Report on a selected product should be prepared and submitted.

Documents

DETAILEDCURRICULUM of BachelorofScienceinChemistry · 2019-07-17 · its limitations. Packing of ions in crystals. Born-Landé equation with derivation and importance of Kapustinskii