Our team of specialized thinkers design and execute strategic communications programs that make our clients’ technologies, products, and services known, understandable, and approachable.

www.lavoiehealthscience.com

DOMAIN EXPERTISE

RARE DISEASE CAR-T GENE THERAPY IMMUNO-ONCOLOGY ONCOLOGY CNS NEURODEGENERATION MED TECH & DEVICES

OPHTHALMOLOGY PRECISION MEDICINE RNA AUTOIMMUNE DISEASES CELL THERAPY CRISPR REGENERATIVE MEDICINE AI, SENSORS & WEARABLES

We help our clients extend visibility and optimize value for their

technologies, products, and services.

INTEGRATED COMMUNICATIONS • Strategy Consulting • Investor Relations & Corporate Communications • Public Relations & Marketing HIGH-TOUCH, AWARD WINNING AGENCY

• Specialized expertise in health and science innovations • 360° approach to media relations, social/digital,

in-person events & presentations • Certified in healthcare communications compliance • Top 30 independent healthcare communications agency

(O’Dwyers 2019) • 50+ awards • Two decades in business • Boston Business Journal’s The List: Largest PR Firms in

Massachusetts • INC. 5000 Hall of Fame - Fastest Growing Private

Companies

GLOBAL REACH AND SCALE IN HEALTH Through our alliance signed in 2019 with the DAS Group of Companies, a division of Omnicom Group, Inc. (NYSE:OMC), LaVoieHealthScience provides its clients with extended reach and global capabilities. This alliance was cemented by the two parties so that LaVoieHealthScience can remain true to its innovative company client base, solving complex communications challenges and extending reach of its clients, while offering additional thinking and opening key markets to them as they develop and grow their companies.

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INTEGRATED COMMUNICATIONS

Our vision is to provide the very best strategic, integrated communications to health and science clients worldwide by leveraging our strategic relationships, and providing industry-tested pragmatic counsel and execution.

Proven Methodologies Through our trademarked methodologies, LHS provides its clients with a proven process for establishing its foundational positioning and messaging (The LHS Immersion®) and blueprint plan, all aligned to key stakeholders. The positioning is supported by LHS message testing and development of a strategic communications plan. Our LHS Fifteen Slide Presentation® provides a foundational set of slides for telling your company’s story based on 15 core concepts.

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INTEGRATED COMMUNICATIONS

Strategy Consulting • LHS Immersion® positioning and messaging

(programs for established and emerging companies) • The LHS 15-Slide Presentation® • The LHS Message Testing™ • Partnering and licensing representation • Market research • Crisis planning and execution Investor Relations & Corporate Communications • IPO communication planning & execution • Strategic counsel • LHS Reach™ Targeting • M&A communications • IR analyst relations • Perception audit • Analyst days and KOL events • Meeting management • Investor outreach • Virtual meetings with investors and analysts • Crisis prevention and communications • Virtual roadshows & summits Public Relations & Marketing • PR strategy and execution • Health and disease awareness • Media relations • Executive visibility • Speaker/media training • Advocacy relations • Event/meeting planning • Access to partnering and financing opportunities • Social media content, development and analytics • Pre/Post commercialization • Corporate materials • Corporate and branding visual identity • Digital influence and new media • Internal communications • Thought leadership • Advocacy relations • Issues/Reputation management • Content development • Analytics • Video, web development & SEO • Crisis prevention and management

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CASE STUDIES

Results • Increased awareness and understanding of company's value proposition • Developed new corporate communications assets including a corporate

profile video and investor presentation • Secured high profile institutional analyst coverage and created and

distributed 20 corporate and financial disclosure released within 3 months

• Coordinated more than 50 initial high-value 1-on-1 meetings with investors and potential business partners, and arranged high visibility broadcast interviews with key reporters to further TFF leadership profiles

Our health science expertise uniquely positions us to help clients make their innovations known, understandable, and approachable to target audiences

through carefully executed strategies and plans.

INVESTOR RELATIONS

Challenge • Build investor relations credibility and

visibility for a recently public NASDAQ company with a novel technology for inhalant therapeutics to solve a major drug delivery challenge

LaVoieHealthScience Solution • Implemented the LHS Immersion®

and blueprint planning process to discover key messages and define visibility strategies

• Develop a “full charge” Investor relations infrastructure program based on best practices to ensure disclosure, transparency, and investor confidence

• Use LHS Reach™ to aggressively extend company outreach within the institutional investment community

• Leverage LHS’ extensive capital markets access to introduce management to key analysts and bankers

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Challenges • International company on NASDAQ with

industry-leading license agreements in Alzheimer’s

• Need for cohesive communications approach and plan

• Seeking to increase visibility in national, business and trade publications in the U.S. market

• Coordinate and negotiate joint communications with partners

LaVoieHealthScience Solution • Establish global, cross-functional team

including corporate, IR and PR across the EU and U.S.

• Develop a strategic communications framework

• Collaborate and negotiate joint communication

• Establish media strategy globally • Develop and finalize corporate assets to

facilitate a successful news announcements

PUBLIC & MEDIA RELATIONS

Results • Cohesive integrated communication

strategy plan with flawless execution • ~100 pieces of media – U.S. • Top mentions and original posts/

articles in Reuters, CNBC, Endpoints, Fierce Biotech, Investor’s Business Daily, BioCentury, BioWorld, STAT and Scrip

• Forbes audience reach 120M • On-message earned media and

analyst coverage

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STRATEGIC COMMUNICATIONS & CORPORATE DEVELOPMENT

Challenge • Build awareness for a European

gene therapy viral vector technologies company targeting U.S. drug developers and investors

LaVoieHealthScience Solution • Revised messages, brand image &

corporate materials • Created an investor presentation

based on the LHS 15 Slide Presentation® methodology

• Identified and conducted outreach to gene therapy developers

• Managed and supported SIRION Biotech roadshow and overall awareness campaign

• Drove awareness through increased news flow planning and media outreach

• Developed social media strategy and monthly planning calendar

Results • 11 license agreements signed, LHS assisted with the first • U.S. revenue as percentage of total revenue increased from 6%

in 2012 to 67% in 2019 • Company revenue increased from approx. $648k in 2012 to

approx. $11M in 2019 • Established company as a high value partner with

differentiated value proposition • Increased social media presences with strategic planning and

content • Developed awareness and relationships with U.S. media

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Results • Developed a video series on the

burden of disease employing personal stories from patients and families

• Planned and executed a successful investor event with high in-person and webinar attendance - On target messaging from leading experts in the field

• Developed and shared original content on social channels during Rett Awareness Month, with a focus on Burden of Disease survey

Challenges • Illuminate breathing difficulties as a

critical element of Rett Syndrome within the scope of Newron’s mission

• Drive focused messaging across stakeholders to communicate the severity of Rett Syndrome symptoms

LaVoieHealthScience Solution • Multi-media approach to

communicate impacts of breathing difficulties

• Increase broad awareness on the impact of this fundamental re-understanding

• Build international visibility for Newron’s Rett Burden of Disease “BOD” Study

• Build advocacy

INTEGRATED COMMUNICATIONS

Effective Video Storytelling

On-Target KOL Messaging

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Results • On-message coverage in relevant publications including:

Medgadget, Proactive Investors, Interventional News, and Drug Delivery Business

• Twitter ad generated 8,076 impressions and 71 engagements • 40 attendees at satellite session on TPT payment status at SIO

conference • Advertorial placed in Interventional News (12,200 subscribed

readers) and 14,000+ views on website • Placed CEO as panelist at BIO CEO & Investor Conference

Challenges • Launch of a new drug delivery device which

received highly coveted transitional pass-through payment (TPT) status from the Centers for Medicare and Medicaid Services (CMS)

• Lack of understanding of the benefits of the TPT process among key stakeholder audiences

LaVoieHealthScience Solution • Create differentiated positioning and messaging

for the launch and promote via media outreach • Educate key stakeholders with earned and paid

approach on the unique advantages of TriNav system and its elite CMS TPT status

• Utilize medical meetings to promote awareness with media and Interventional Radiologists

• Develop Twitter ad using geotargeting around Society of Interventional Oncology (SIO) conference

• Identified relevant advertorial opportunities

NEW PRODUCT LAUNCH

Meet the Senior Team

Sharon Correia EXECUTIVE VICE PRESIDENT & CHIEF STRATEGY OFFICER

Lisa DeScenza VICE PRESIDENT, INTEGRATED COMMUNICATIONS

Ella Deych Cerminara VICE PRESIDENT, FINANCE & CHIEF OPERATIONS OFFICER

Sharon Choe SENIOR VICE PRESIDENT, INVESTOR RELATIONS & BUSINESS DEVELOPMENT

Nadia Tran EXECUTIVE BUSINESS PARTNER

Paul Sagan VICE PRESIDENT, INVESTOR RELATIONS & CORPORATE COMMUNICATIONS

Barrett McGrath SENIOR BUSINESS DEVELOPMENT ADVISOR

Gina Nugent SENIOR COMMUNICATIONS ADVISOR

Katie Gallagher ACCOUNT DIRECTOR, PR & MARKETING

Brian Pinkston ACCOUNT DIRECTOR, INVESTOR RELATIONS & CORPORATE COMMUNICATIONS

Donna LaVoie PRESIDENT & CEO

Douglas Russell SENIOR VICE PRESIDENT, CLIENT SERVICES & PR/ MEDIA

Harriet Ullman ASSISTANT VICE PRESIDENT, PR & PRODUCT COMMUNICATIONS

Samantha Choinski MEDIA RELATIONS SPECIALIST

Emmie Twombly MEDIA RELATIONS SPECIALIST

UPDATED 5/20

www.lavoiehealthscience.com

Agency Headquarters One Thompson Square, Suite 503 Boston, MA 02129 617.374.8800 New York 58 Greenpoint Avenue Brooklyn, NY 11222 617.374.8800 x106

Email: info@lavoiehealthscience.com

https://www.linkedin.com/company/lavoie-group

@lavoiegroup