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VISIT OUR WEBSITE lynnsagebreastcancer.org

19TH ANNUAL

LYNN SAGE BREAST CANCER SYMPOSIUM SEPTEMBER 14-17, 2017Chicago Marriott Downtown Magnificent Mile

SYMPOSIUM CHAIR William Gradishar, MD

SYMPOSIUM CO-CHAIRS Monica Morrow, MD V. Craig Jordan, OBE, PhD, DSc Nora Hansen, MD

Referred to as the most valuable breast cancer meeting worldwide for the practicing clinician, the Lynn Sage Breast Cancer Symposium provides 3.5 days of formal presentations and interactive case discussions. For 19 years, this multidisciplinary CME program has been bringing together leading national and international medical, surgical, and radiation oncologists to present, debate, and evaluate cutting-edge technology and approaches in the management of breast cancer.

Progress across all aspects of patient care, including prevention, screening, detection, and survivorship, as well as in the primary treatment modalities of surgery, radiation therapy, endocrine therapy, cytotoxic chemotherapy, and novel biologic therapies are leading to new strategies and therapeutic options. The symposium focuses on the close cooperation required for effective multidisciplinary management of patients with breast cancer.

Educational Objectives

At the conclusion of this activity, participants will be able to:

» Practice current management approaches to high-risk benign breast lesions.

» Describe factors influencing the choice of initial therapeutic approaches— neoadjuvant chemotherapy, mastectomy or oncoplastic breast conservation in operable breast cancer.

» Identify the multidisciplinary challenges and opportunities associated with the use of neoadjuvant chemotherapy in operable breast cancer.

» Apply optimal pain management strategies in patients with breast cancer.

» Employ optimal strategies for overcoming endocrine resistance by incorporating targeted therapies.

» Cite the clinical and molecular factors that determine the optimal duration of adjuvant endocrine therapy.

» Utilize optimal surgical and medical interventions in the elderly with breast cancer.

PROGRAM DESCRIPTION

CONFIRMED FACULTY

Benjamin Anderson, MD University of Washington

Jose Baselga, MD, PhD Memorial Sloan Kettering Cancer Center

Richard Bleicher, MD Fox Chase Cancer Center

Thomas Buccholz, MD The University of Texas MD Anderson Cancer Center

Harold Burstein, MD, PhD Harvard Medical School

Massimo Cristofanilli, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Sarah Friedewald, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

William Gradishar, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Nora Hansen, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Kevin Hughes, MD Massachusetts General Hospital

Arti Hurria, MD City of Hope

Reshma Jagsi, MD, PhD University of Michigan

V. Craig Jordan, OBE, PhD, DSc The University of Texas MD Anderson Cancer Center

Malcolm Kell, MD Mater Misericordiae University Hospital

Seema Khan, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

John Kim, MD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Tari King, MD Dana-Farber Cancer Institute of Harvard Medical School

Jennifer Ligibel, MD Harvard University

Elizabeth Mittendorf, MD, PhD The University of Texas MD Anderson Cancer Center

Monica Morrow, MD Memorial Sloan Kettering Cancer Center

Hyman Muss, MD University of North Carolina Lineberger Comprehensive Cancer Center

Ruth O’Regan, MD University of Wisconsin Carbone Cancer Center

Joyce O’Shaughnessy, MD Texas Oncology & US Oncology/ Baylor Sammans Cancer Center

Judith Paice, PhD, RN Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Lajos Pusztai, MD Yale University

Abram Recht, MD Beth Israel Deaconess Medical Center/ Harvard Medical School

Mark Robson, MD Memorial Sloan Kettering Cancer Center

Stuart Schnitt, MD Beth Israel Deaconess Medical Center/ Harvard Medical School

Andrew Seidman, MD Memorial Sloan Kettering Cancer Center

Kalliopi Siziopikou, MD, PhD Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Dennis Sgroi, MD Massachusetts General Hospital

Lawrence Solin, MD Albert Einstein Healthcare Network

Fraser Symmans, MD The University of Texas MD Anderson Cancer Center

Melinda Telli, MD Stanford University

Julia Trosman, PhD, MBA Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Gary Ulaner, MD Memorial Sloan Kettering Cancer Center

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Register by July 31, 2017 for early bird discount

Faculty Disclosure Current guidelines state that participants in CME activities should be made aware of any affiliation of financial interest that may affect the speaker’s presentation. Each speaker has been requested to complete a faculty disclosure form. The names of faculty members declaring a relationship or who will be discussing off–label usage will be indicated in the course syllabus.

SEPTEMBER 14 THURSDAY8:00 am Breakfast & Exhibits

9:00 am Symposium Welcome William Gradishar, MD Symposium Chair

Session 1: Supportive Issues or Art of Oncology Session Chair: Nora Hansen, MD

9:15 am Current Pain Management Guidelines Judith Paice, PhD, RN

9:45 am The Imperative of Mandated Care Models Julia Trosman, PhD, MBA

10:15 am Exercise, Diet, Obesity, and Breast Cancer Jennifer Ligibel, MD

10:45 am Break

11:00 am Computer-Based Physician Support in Breast Cancer Decision Making Andrew Seidman, MD

11:30 am Questions and Answers

11:45 am Lunch Break

Session 2: Breast Pathology for the Non-Pathologist Session Chair: Kalliopi Siziopikou, MD, PhD

1:00 pm Do All High Risk Lesions Still Require Surgical Excision? Stuart Schnitt, MD

1:30 pm Classic and Newer Multiparametric Prognostic and Predictive Markers for Breast Cancer Dennis Sgroi, MD

2:00 pm International Guidelines for pCR or Updates to Staging Fraser Symmans, MD

2:30 pm Lobular Carcinoma in Situ (LCIS) Current Concepts and Challenges Tari King, MD

3:00 pm Questions and Answers

3:15pm Break

Session 3: Challenging Clinical Cases Moderator: William Gradishar, MD 3:45 pm Case Discussions Confirmed Faculty 5:00 pm Adjourn

5:00 – 6:00 pm Welcome Reception

7:30 am Breakfast & Exhibits

Session 4: Imaging and Risk Session Chair: Sarah Friedewald, MD

8:30 am Refining Indications for PET Scanning: Present and Future Gary Ulaner, MD

9:00 am MRI: What is the Evidence? Lawrence Solin, MD

9:30 am Understanding and Managing Genetic Risk Beyond BRCA Mark Robson, MD

10:00 am Break

10:30 am Topical Approaches to Chemoprevention Seema Khan, MD

11:00 am Questions and Answers

11:15 am LYNN SAGE DISTINGUISHED LECTURER TARGETING THE BREAST CANCER GENOME AND THE SHAPING OF PRECISION MEDICINE Jose Baselga, MD, PhD

12:15 am Lunch Break

Session 5: Current Issues in Surgery and Adjuvant Therapy Session Chair: Seema Khan, MD

1:30 pm Adjuvant Considerations in Premenopausal Women Ruth O’Regan, MD

2:00 pm Fat Grafting: Indications, Safety, Results Malcolm Kell, MD

2:30 pm TN Breast Cancer: Where are We Now? Joyce O’Shaughnessy, MD, PhD

3:00 pm Break

3:30 pm Oncoplastic Surgery or Mastectomy and Reconstruction: Which is the Best Choice? Elizabeth Mittendorf, MD, PhD 4:00 pm What is the Optimal Duration of Endocrine Therapy? William Gradishar, MD

4:30 pm Making Endocrine Therapy Better V. Craig Jordan, OBE, PhD, DSc

5:00 pm Questions and Answers

5:15 pm Adjourn

SEPTEMBER 15 FRIDAY

7:30 am Breakfast & Exhibits

Session 6: Challenging Clinical Scenarios Session Chair: Massimo Cristofanilli, MD

8:30 am Overcoming Resistance in ER+ Disease Massimo Cristofanilli, MD

9:00 am Surgery or RT for Oligometastases Thomas Buchholz, MD

9:30 am Sequencing of HER-2 Therapy Harold Burstein, MD, PhD

10:00 am Break

10:30 am Controversies in DCIS Management Richard Bleicher, MD

11:00 am Questions and Answers

11:15 am THE CONNIE MOSKOW MEMORIAL LECTURE: BREAST CANCER AS A GLOBAL DISEASE – ARE WE UP TO THE CHALLENGE? Benjamin Anderson, MD

12:15 pm Lunch Break

Session 7: Breast Cancer in the Elderly and Reconstructive Issues Session Chair: Monica Morrow, MD

1:30 pm Why do We Need Geriatric Assessment? Arti Hurria, MD

1:50 pm Local Therapy Issues in Elders Kevin Hughes, MD

2:10 pm Adjuvant Therapy for HER-2+ and TN cancer in Elders Hyman Muss, MD

2:30 pm Selecting the Right Reconstruction for the Right Patient John Kim, MD

2:50 pm Reconstruction and Radiation Reshma Jagsi, MD, PhD

3:10 pm Questions and Answers

3:30 pm Break

3:45 pm Multidisciplinary Tumor Board Monica Morrow, MD

5:00 pm Adjourn

SEPTEMBER 16 SATURDAY

Session 8: Neoadjuvant Controversies Session Chair: William Gradishar, MD

8:30 am Predicting Response to NAC Melinda Telli, MD

9:00 am Selecting Operable Patients for Primary Surgery vs NAC Monica Morrow, MD

9:30 am Managing Residual Disease after NAC Lajos Pusztai, MD, PhD

10:00 am RT after NAC: What to do While Awaiting Trial Results? Abram Recht, MD

11:00 am Adjourn

SEPTEMBER 17 SUNDAY

Registration Advance registration is encouraged, as space and materials are limited. The registration fee includes conference tuition, CME credits, materials, four breakfasts, breaks and an evening reception.

Type Discounted Regular Through July 31 After July 31

General $525 $625

Fellow/Student/Trainee $275 $375

Nurse/Physician Assistant/Nurse Practitioner $275 $375

Industry Representative $725 $825

ADDITIONAL FEES

Lunch Ticket (no refunds) $25/day

Breakout Session Ticket $50/day

Refund/Cancelation Policy Registration fees less a $50 administrative handling fee are refundable if a written request is received on or before August 18, 2017. For further information, please call 312.695.1392 or email cancer@northwestern.edu.

Award ProgramsThe Lynn Sage Symposium Scholars Program is available for fellows and residents, and the Chicago Sister Cities Medical Initiative Program is available for international physicians. Detailed information on these award programs and application processes is available online at lynnsagebreastcancer.org. Awards are made possible through the generous support of the Lynn Sage Cancer Research Foundation.