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Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa Lilian

Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

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Page 1: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Department of Human Anatomy

The Urinary System

The State Medical and Pharmaceutical University “Nicolae Testemitanu”Republic of Moldova

Lecturer Globa Lilian

Page 2: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Uro-genital Apparatus

Urinary Systemfor secretion and

discharge of the urine

Genital Systemconcerned with process of

reproduction

Have common sources and ways of the development, topographic sites, blood and nerve supply

Page 3: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Overview of the Urinary System

4 components

Page 4: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Functions Controlling the water and electrolyte balance,

maintain the acid-base balance Regulates blood concentrations of sodium,

potassium, chloride and calcium Regulates blood volume and blood pressure Production of urine- waste products (urea and

uric acid) Reabsorb important nutrients from urine Endocrine (rennin, angiotensin, erythropoietin)

Page 5: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Anatomy

1. Kidney

Each kidney is about:

Length 11.25 cm

Breadth 5-7.5 cm

Width 2.5 cm

The weight:

Male 125-175 g

Female 115-155 g

Page 6: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Anatomy

2. Ureter* Connects

kidney to

urinary

bladder

Page 7: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Anatomy

3. Urinary

bladder

* Stores

urine

Page 8: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Anatomy

4. Urethra

* Drains

urine from

bladder

Page 9: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 10: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 11: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Coverings of the Kidneys

The kidneys have the following coverings:

Fibrous capsule Perirenal fat Renal fascia with

anterior and posterior layers

Pararenal fat

Page 12: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Fixation of the Kidneys

The elements that held kidneys in position:

Peri- and para renal fat Renal fascia with anterior and posterior layers Vascular pedicle Intrabdominal pressure

Page 13: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Anatomy of the Kidney

Outer cortexInner medulla

Page 14: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

MedullaMedulla dividedinto pyramids and columa renalis

One pyramid with corresponding cortex form renal lobe

Page 15: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

CortexCortex divided

into pars convoluta and pars radiata

Page 16: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Calyx

One minorcalyx per pyramid

Page 17: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Minor Calyx

Page 18: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Major Calyx

Fusion of severalminor calyces

Usually 2-3major calycesper kidney

Page 19: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Fornical Apparatus

Page 20: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Renal Pelvis

Fusion of major calyces

Opening to theureter

Page 21: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Human Kidney

Page 22: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 23: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Urogram

Page 24: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 25: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 26: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 27: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

The Nephron

Basic structural and functional unit of kidney

Page 28: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 29: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

The Nephron

Filtration of blood Production of urine 1,25 million per kidney 85 miles of tubes per kidney

Page 30: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Components of Nephron

1. Renal corpuscle:a. Glomerulus – a net-work of convoluted capillaries

b. Glomerular (Bowman’s) capsule – a hollow chamber surrounding the glomerulus

2. Proximal convoluted tubule

3. Loop of Henle (descending and ascending limbs)

4. Distal convoluted tubule

Page 31: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

The Nephron

Page 32: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

The Nephron

Epithelia filterthe urine

Page 33: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Glomerulus

Page 34: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Glomerulus and Capsule

afferent arteriole

efferent arteriole

urine

Page 35: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Proximal Convoluted Tubule

Page 36: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Loop of Henle

only part foundin medulla

Page 37: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

The Juxtaglomerular Apparatus

afferent arteriole

efferent arteriole

urine

Page 38: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Distal Convoluted Tubule

Page 39: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Collecting (Straight) Duct

Page 40: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Collecting Duct

Not part of nephron Collects urine from distal convoluted tubules

of many nephrons Opens at tip of pyramid Urine drains into minor calyx

Page 41: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Collecting Duct

Page 42: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 43: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Important Relations, Right KidneyAnteriorly:

the suprarenal gland, the liver, the descended part of the duodenum, coils of jejunum, the right colic flexure.

Posteriorly: the diaphragm, the XII-rib, the psoas, quadratus lumborum, and transversus

abdominis muscles (the renal lodge) the costodiaphragmal recess of pleura, the subcostal, iliohypogastric and ilioinguinal nerves

Page 44: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Important Relations, Left KidneyAnteriorly:

the suprarenal gland, the spleen, the stomach, the pancreas, coils of jejunum, the left colic flexure.

Posteriorly: the diaphragm, the XI-XII rib, the psoas, quadratus lumborum, and transversus

abdominis muscles (the renal lodge) the costodiaphragmal recess of pleura, the subcostal, iliohypogastric and ilioinguinal nerves

Page 45: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Anterior Relation of both Kidneys

1 – area hepatica;

2 – area colica;

3 – area jejunalis;

4 – area duodenalis;

5 – glandulae suprarenales;

6 – aa. renales;

7 – vv. renales;

8 – area gastrica;

9– area lienalis;

10 – area pancreatica;

11– area colica.

Page 46: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 47: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Ureter

Drains urine from kidney to urinary bladderLength 25-30 cm

Four parts:

1. Abdominal

2. Pelvic

3. Intramural

4. Intravesical

Page 48: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Ureter

Three constrictions:

1. Ureteropelvic

2. Iliac

3. Ureterovesical

Page 49: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Urinary Bladder

ureter opensinto posteriorwall ofbladder

Surfaces:*Posterior (fundus or base)*Anterior (contacts with pubic symphysis and retropubic space of Retzius )*Superior (covered by peritoneum)Apex continues with median umbilical ligamentNeck contains internal urethral sphincter

Page 50: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 51: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

External urethral

Sphincter

Internal urethral

Sphincter

Page 52: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Urinary Bladder -- Male

Page 53: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Urinary Bladder -- Female

Page 54: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Development of the kidney

Ureteric Bud• Ureter• Pelvis • Major Calyces• Minor Calyces• Collecting Tubules

Metanephrogenic Cup• Glomerular capsule (covers a cluster

of capillaries - Glomerulus )• Proximal• Loops of Henle• Distal convoluted tubules

Three sets of structures appear during the development of the urinary system:

1. Pronephros2. Mesonephros (Mǖllerian Duct)3. Metanephros (responsible for permanent kidney)

arise from two sources:

Page 55: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

Abnormalities

Page 56: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 57: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 58: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 59: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 60: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa
Page 61: Department of Human Anatomy The Urinary System The State Medical and Pharmaceutical University “Nicolae Testemitanu” Republic of Moldova Lecturer Globa

VVĂ MULȚUMESC PENTRU Ă MULȚUMESC PENTRU ATENȚIE!ATENȚIE!