UNIVERSITY OF OXFORD

Department of Chemistry

Undergraduate Course Handbook

Academic year 2016 - 2017

http://www.chem.ox.ac.uk

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ContentsContents iMessagefromHeadofDepartment 1HowtousethisHandbook 1Introduction 2AimsandObjectives,TeachingandExamination 3ExaminationConventionsinChemistry 6FirstYear2016-17 12SecondYear2016-17 14ThirdYear2016-17 16FourthYear2016-17 17Prizes 17RecommendedCoreTextbooks 18CalculatorsforWrittenExaminationsinChemistry 18ImportantDates 19SyllabusforPrelims2016-17 20SyllabusforPartIA2016-17 22SyllabusforPartIB2016-17 27SyllabusforSupplementarySubjects2016-17 32AcademicStaff 34UniversityPolicies 36

This Handbook applies to students starting the course inMichaelmas Term 2016. The information in thishandbookmay be different for students starting in other years. Suggestions for future editions are alwayswelcomepleasecontactnina.jupp@chem.ox.ac.uk

The Examination Regulations relating to this course are available athttp://www.admin.ox.ac.uk/examregs/2016-17/pexaminchem/studentview/and

http://www.admin.ox.ac.uk/examregs/2016-17/hschoofchem/studentview/. If there is a conflict betweeninformation in this handbook and the Examination Regulations then you should follow the ExaminationRegulations.IfyouhaveanyconcernspleasecontactNinaJupp,<nina.jupp@chem.ox.ac.uk>.

TheinformationinthishandbookisaccurateasSeptember2016,howeveritmaybenecessaryforchangestobe made in certain circumstances, as explained at http://admissions.chem.ox.ac.uk/course.aspx(www.ox.ac.uk/coursechanges)/PG (www.graduate.ox.ac.uk/coursechanges) webpage. [If such changes aremade the departmentwill publish a new version of this handbook togetherwith a list of the changes andstudentswillbeinformed.]

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MessagefromHeadofDepartmentI would like to offer a warm welcome to all newstudents starting the Chemistry course here inOxford.Youarejoiningagroupof180-190ChemistsinthefirstyearfromallovertheUK,EuropeandtheWorld. Although many of your initial contacts atOxford will be with students and tutors from yourowncollege,Iamsurethatyouwillalsogettoknowmany of the Chemists from other colleges as youmeet them in lecturesand in the teaching labshereintheDepartment.InfacttheChemistryDepartmentis one of the largest, if not THE largest, Chemistrydepartments in the world with around 750undergraduates, 450 postgraduates and 500 or soacademic,research,supportandadministrativestaff.ThisDepartmentisconsistentlyrankedamongstthevery best for teaching in the UK, and its researchstanding places it in the top 10 of Chemistrydepartments worldwide. But Oxford Chemistry isalsoavibrantandfriendlycommunityandIamsurethatastimegoesonyouwillstart to feelasenseofbelonginghere!

We hope that you will find Chemistry an exciting,challenging,satisfyingandenjoyablesubjecttostudyatUniversity.Ouraimsarenotsimplytoprovideyouwithavastknowledgeofchemistrybutalsotohelpyou develop your intellectual and creative skills,(such as logical and lateral thinking, problemsolving), and your practical skills. We aim toencourage and stimulate you to become the nextgeneration of leading researchers and teachers inchemistry. At the same time there is a need forscientificallyeducatedleadersinallwalksoflife,andwhatever your ultimate career choice we areconfident that an Oxford Chemistry degree willprovideavaluablefoundation.

Overthenextfewyearsyouwillcometounderstandjust how broad Chemistry is as a subject, and how

central a science. The Chemistry curriculum rangesfrom the boundaries with applied mathematics tomolecularbiologyandhasimportantapplicationsinmost of the major global challenge areas such asHealth, Energy, Environment and Climate, Securityand Communications. But you will also experiencethe rigour and depth of Chemistry as an academicdiscipline,whichenablesittolieatthecoreofmanyscientificendeavours.

Oxfordhasworld-classChemistryresearchfacilities,providedbyourChemistryResearchLaboratory,andmanyofyouwillhaveanopportunitytoworkthereinaresearchprojectorinyourPartIIyear.ThePartII experience – a full year of research – remainsunique amongstUK Chemistry courses. In 2017wereachthe100thanniversaryofthecompletionofthefirstPart IIyearatOxfordand Ihopeyouwillhavethe opportunity to celebrate this anniversary withus.

My final word is simply to remind you of thefantasticopportunityyouhavehere–butlikemanythings in life, youwillonlygetoutwhatyouput in,and it is up to you whether youmake the most ofthatopportunity.

Although we will teach you in lectures, lab classesandtutorials,anOxfordChemistryeducation isalsoabout you developing your ability to learn foryourself,toresearchnewmaterialsandengageyourmindintheintellectualrigourandexcitementofthissubject. I wish you all an enjoyable and successfultimeatOxford.

MarkBrouard,HeadofDepartment

HowtousethisHandbookFirstYearstudentsshouldreadthewholeHandbook.Those in subsequent years need only look at therelevantyearsections.

Appendicesgivethelecturecontentsrelevantforthevarious Examinations. Also given are someimportante-mailaddresses forcontactingmembersoftheAcademicStaff,ashortreadinglistfortheFirstYears and information about the Chemist’s JointConsultativeCommittee(CJCC).

Members of the Academic Staff will be happy toanswer any questions you might have, but forparticular information about College teaching,studentsshouldcontacttheirTutors.

Further information about the course can beobtainedfromtheDepartmentofChemistrywebsitehttp://www.chem.ox.ac.uk/ and from the FacultyOfficeintheInorganicChemistryLaboratory.

Lecturetimetablesaresubjecttochange.Fullanduptodateinformationonlecturetimetablesmaybefoundon theDepartment's lecture timetablewebpage:http://teaching.chem.ox.ac.uk/ or indiary form from themain Chemistry web page: http://www.chem.ox.ac.uk/ by selecting Course Information from theUndergraduatemenuandthenclickingonLecturetimetable.TheExaminationdatesgiveninthishandbookarebasedoninformationavailableinSeptember2016.Theyareonlyaroughguide,andthedefinitivedatesare thosepublishedby theExaminers.Forup todate informationregarding theExaminationscheckon thewebpage:http://www.ox.ac.uk/students/academic/exams/entrytheonlyofficialtimetable.

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IntroductionThe Oxford Chemistry School has recently beenadmitting around 180 - 200 undergraduates p.a.Thereareapproximately65full-timeProfessorsandLecturerswithalargesupportstaff.

Safety

Chemistry is a practical subject, and an importantpart of the course is to train you to conductexperiments safely and to assess andminimise anyrisks before starting an experiment. Your safety isourtoppriority,butalargepartofthisisdependenton you. An important resume of the main safetyconcerns in the lab can be found on the web athttp://course.chem.ox.ac.uk/safety.aspx. In additionthe lab manuals have more detail on eachexperimentandtheprocedureforriskassessment.

Libraries

Undergraduateswillfindmostoftheirneedsmetbywell-resourced College libraries. If your library iswithoutabookyouneed,youshouldtellyourTutororyourCollegeLibrarianorinformthelibrariansintheRadcliffeScienceLibrary(RSL).TheRSLinParksRoad has a comprehensive collection of chemistrybooksandjournals,whichyoumayborrowprovidedyouhave youruniversity cardwith you.TheRSL isboth a reference and a lending library. It is aninvaluableresourceforstudents.AccesstotheRSLisfromParksRoad.

The RSL has a web page detailing both print andelectronic chemistry resources available,http://www.bodleian.ox.ac.uk/science/subjects/chemistry

InformationTechnology

UndergraduateswillhaveChemistryfocusedITskillstraining workshops as part of the undergraduatepractical course and opportunity to use the centralIT services training courses for more general ITtrainingrequirements.Collegesalsohavecomputingfacilities for their undergraduates and there is aUniversity-wide network and wireless network,whichenablesstudentstoaccessdepartmentalsites,thepracticalcourseandtheInternet,withoutcharge.

Undergraduateswill also receive an e-mail accounton the University computing system. All new userswillbeaskedtosignanundertakingtoabidebytheUniversity rules on the use of computershttp://www.it.ox.ac.uk/rules/. The URL for theUniversity Computing Service ishttp://www.it.ox.ac.uk/.

The Chemistry Department follows the generalguidelines laid downby theUniversity in regard tothe provisions of the Data Protection Act 1998(http://www.admin.ox.ac.uk/councilsec/dp/index.shtmlfordetails).

ChannelsofCommunication

Academic Staff have pigeon-holes in the buildingswhere they have offices and in their Colleges. Staffmay also be contacted by telephone or by e-mail.Mostofthempreferemail,whichisusuallythemostefficientway. A list of e-mail addresses and collegeaffiliationsisgiveninAppendixF.

Much administrative information about the courseandtheExaminationsissenttostudentsbye-mail.Itis very important therefore that students using e-mail accounts other than their college account(joe.bloggs@college.ox.ac.uk), set the forwardingfacility appropriately and check their e-mailregularly. The majority of information that is sentfromtheFaculty,forexample,regardinglastminutelecture changes, examination information anddeadlines that need to bemet, is sent to individualstudents using email. It is therefore necessary formailboxestobekeptclearatalltimes.

SupportforStudents

Colleges provide pastoral support through subjecttutors and other welfare officers. The universitycounselling service offers confidential help andadvice to students, who can access it through theircollegewelfareofficers.

TheDisabilityAdvisoryServicehttps://www.ox.ac.uk/students/welfare/disabilityshould be contacted for advice on sensory ormobility impairments, health conditions, specificlearning difficulties, autistic spectrum conditions ormental health difficulties. The disability lead in theDepartmentisnicholas.green@chem.ox.ac.uk,whoisresponsible for strategic oversight or provision fordisabled students, and the disability co-ordinator isnina.jupp@chem.ox.ac.uk, who coordinates andorganisestheimplementationofthisprovision.

TheChemist’sJointConsultativeCommittee(CJCC)

The CJCC is a forum for the exchange of viewsconcerning the undergraduate and postgraduatecourses. The matters covered by this Committeeinclude, i) the teaching arrangements, lectures, andseminars;organisationandcoverage;ii)thepracticalcourses: composition, organisation, and formalrequirements, safety; iii) the syllabus and structureofExaminations; iv) library facilities; v) thegeneralwelfare of students, in so far as it affects theDepartment(welfaremattersareprimarilyaCollegeconcern).

Meetings are held twice a term (except in TrinityTerm,whenthereisonlyonemeeting).Collegesarepaired, and each pair of Colleges provides arepresentativeforoneyear.Forfurtherdetailssee

http://teaching.chem.ox.ac.uk/

The CJCC comprises fourteen undergraduatemembers, three postgraduate representatives and

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six seniormembers. It is chairedby theDirector ofStudies.Thereisaseparatecommitteeforgraduates.The Maths, Physical and Life Sciences Division(MPLS)has a similar forumwith a broader agenda,on which the chemistry department has studentrepresentation.

There is also student representation on theChemistryAcademicBoard,which is the committeethatoverseestheteachinginthedepartment.

AimsandObjectives,TeachingandExamination

TheChemistryCourse-AimsandObjectives

• toengendersuchqualitiesaswillbeneededbyour students for them to become the nextgeneration of outstanding research chemistsandteachersofchemistry

• to stimulate in our students a deep interest inchemistry as a rich academic discipline in itsown right, and an appreciation of howmodernchemistry underpins a vast range of science,technologyandmedicine

• to provide intellectual development, skillsdevelopment and academic challenge for thebestandbrightestofstudentsinthiscountry,soastoequipthemforawiderangeofcareersandrolesinsociety

TheMasterofChemistrydegreeisfullyaccreditedattheMasters levelbytheRoyalSocietyofChemistry.TheUniversityAwardsFramework(UAF)awardthecourseFHEQLevel7,minimumcreditvalueof180.Thefullcoursespecificationcanbefoundfromwebaddress:http://teaching.chem.ox.ac.uk/

Researchandteaching

The Department of Chemistry has an internationalreputation for researchand thisUniversitybelievesthat there are many benefits to the teaching of itscourses that flow from this high level of researchactivity.Thetutorsandlecturerswithwhomyouwillinteractduringthiscoursearenotonlyemployedtoteachyou, but are also (innearly all cases) activelyengaged in the direction of, or participation in, oneormoreof thewide rangeof researchprojects thatcontribute to the department’s research reputation.Many of the academic staff in this department arerecognised internationally as leaders in their ownfieldofspecialisation.

The impact of research on teaching in thisdepartment may take many forms: tutors andlecturers including their own data or ideas fromresearch in their teaching; the regular updating ofreading lists and curricula to reflect researchdevelopments; the development of research skillsand research-based approaches to study throughyourparticipation in researchprojects (particularlyin thePart II); special topicsprovidedasoptions inthe third year; the use of research equipment inpractical classes; access to research seminars; themanyopportunities tomeetwith research studentsand members of the faculty, particularly at the

research project stage; experience of preparingresearch reports including papers for externalpublicationinsomecases.Youwillbeencouragedtodevelop the ability to interpret and criticallyappraisenewdataandtheresearchliterature,andtobuild the sense that scientific knowledge iscontestable and that its interpretation may becontinuallyrevisited.

DepartmentalandCollegeTeaching

The teaching of the course is carried out throughlectures,practicalworkinthelaboratories,tutorialsin the colleges (to which academic staff are alsoattached),andclasses.

The lecture courses are comprehensive andchallenging.Lecturersareallowedflexibilityintheirapproach,whichfrequently leadstothe inclusionofmaterial reflecting developments in the field, notcontained in standard textbooks. Lectures aregenerally regardedasessential,but technically theyarenotcompulsory.Noattendancechecksaremade,but only foolish idlers cut lectures. Printed notes,problem sheets and other handouts frequentlysupport lectures and where appropriate they areonline:http://course.chem.ox.ac.uk/home.aspx

Students need to learn how to take good lecturenotes, andsupplement themwith theirownprivatestudy, using textbooks and other sourcesrecommended by the Lecturers and their Tutors.Feedback questionnaires are provided and theircompletion is encouraged because it helps usimprovewhatweoffer.During the first threeyearspractical work is compulsory. Practical work isassessed and practicals have to be written up indetail andmarked. Themarks for second and thirdyearpracticalscount towards the finaldegreeclass.There is a practical course database onwhich bothyou and your tutors can follow your progress andwhere you can book laboratory slots. You can findthis at http://teaching.chem.ox.ac.uk/. Details ofarrangements for the practical courses is online:http://course.chem.ox.ac.uk/practicals.aspx

Tutorial teaching (typically 2 or 3 in a group) isbased in your College. Your tutor will provideguidance as to what to study, and in what order,coupled with week-by-week work assignments.Theseassignmentsaregenerallyproblems,withtheoccasional essay. College Examinations 'Collections'monitor students' progress during the intervalsbetweenUniversity Examinations, and students are

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given termly reports on their progress. Each termyour tutors will write a report on your progress,whichwillbeavailabletoyourCollegeandtoyouviaanonline systemcalledOxCORT, andyoualsohavetheopportunitytogivefeedbackonyourtutorials.

TheRelationshipbetweenTutorialTeachingandtheLectureCourse

There isno formal linkbetweenthe lecturecoursesand the tutorial teaching you will get from yourCollege Tutors, but most of the College Tutors arealso University Lecturers and so know what isneededandwillmatchwhattheyteachtothelecturecourses, backing up areas of difficulty and helpingyouwithproblems.Theywillalsoas faraspossibletailor your tutorial work to your needs. Lecturerssupplyproblemsets to their courseson theWebathttp://course.chem.ox.ac.uk/home.aspx and thesemaybeusedasthebasisoftutorialwork.

Teachingnorms

Ineachofthefirstthreeacademicyearsstudentscanexpect aminimum of 190 lectures provided by thedepartment, and a norm of 48 hours of collegetutorials and classes. The department will alsoprovide at least 400 timetabled hours of practicalsoverthefirstthreeyears.

Skillsdevelopment

Students taking the Oxford Chemistry course areexpected to gain the following skills via lectures,classesandtutorials:

• Theabilitytocollate,assimilateandrationaliseawide range of chemical facts, concepts andprinciples.

• An awareness and understanding of issueswherechemistryimpingesonotherdisciplines.

• Theabilitytoreasonlogicallyandcreatively.• The ability to communicate effectively, both in

writingandorally.• Problem solving in a variety of contexts, both

familiar and unfamiliar, including thedemonstration of both self-direction andoriginality.

• Numeracyandmathematicalskillsincludingtheappropriateuseofunitsandtheassessmentandpropagationoferrors.

• Numerical, computational and IT informationretrievalcapabilities.

• and the following skills, primarily via theundergraduate practicals, including compulsoryITpracticals,andthePartIIresearchyear:

• The ability to conduct an experimentalinvestigationpreciselyandsafely.

• Theabilitytodesignanappropriateexperimenttosolveaproblem.

• The ability to interpret complex experimentalinformationandinferappropriateconclusions.

• TheabilitytoapplyITmethodsfordataretrievaland archiving and to use a wide variety ofstandard Chemistry orientated software

packages such as those for structure drawing,spectralsimulationetc.

• The ability to read and interpret the primaryliterature.

• Abilitytoworkinateamandinteractpositivelywith other people, including those in otherdisciplines.

• The ability to exercise initiative and personalresponsibility.

• Time management, project organisation anddecisionmakingabilities

• An ability to communicate effectively via bothwrittenandverbalreportsandpresentations.

Awiderangeofinformationandtrainingmaterialsisavailabletohelpyoudevelopyouracademicskills–including time management, research and libraryskills, referencing, revision skills and academicwriting–throughtheOxfordStudentswebsite

http://www.ox.ac.uk/students/academic/guidance/skills

Vacations

AtOxfordtheteachingtermsareshort.Itisthereforeessential that you set aside a significant amount oftime each vacation for academic work. The courseassumesthatyouwilldothis.YourTutorsmayalsosetyousomespecificvacationwork.

Guidanceonpaidwork

www.ox.ac.uk/students/life/experience

Examinations

There are Examinations in the first three years:Prelims,PartIAandPartIBrespectively.ThePartIAandPartIBsystemwasintroducedin2004/5andarevised system was introduced in 2010/11. Pastpapers and examiners’ reports can be viewed fromthe link http://teaching.chem.ox.ac.uk/. Part II isexaminedbythesisandviva.

Instructions for entering University Examinationsand examination timetables can be found viahttp://www.ox.ac.uk/students/academic/exams/entry

Information on (a) the standards of conductexpected in examinations and (b)what todo if youwouldlikeexaminerstobeawareofanyfactorsthatmay have affected your performance before orduring an examination (such as illness, accident orbereavement) are available on the Oxford Studentswebsite

www.ox.ac.uk/students/academic/exams/guidance

Thecurrentexaminersresponsibleforexaminationsin years 1 – 4, can be found fromhttp://intranet.chem.ox.ac.uk/committee-members.aspx

Prelims

This Examination comprises four papers coveringthe traditional areas of Inorganic, Organic and

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Physical chemistry, together with Mathematics forChemistry.The first threeof theseareverybroadlybased,and include topics fromBiologicalChemistryand Physics, which are presented in a chemicalcontext.StudentssitthePreliminaryExaminationinallfoursubjectsinJuneofthefirstyear.Thelevelofthe Examinations is set so that with reasonablecommitment the vast majority of students arecapable of passing. Distinctions are awarded forexcellent performance in the Examination. Failedpapers can be re-taken in the following September,with thepermissionof the student’sCollege,butallmust be passed at no more than two sittings. It isnecessary to have passed all the examinations inPrelims, including fulfilling practical and ITrequirements,beforeproceeding to thesecondyearcourse.

Thematerial in the firstyearcourse is fundamentalcore material. It is necessary to assimilate it allthoroughly,notjusttopassPrelimsbutalsobecauselater parts of the course depend and build on it.Prelimsmaterial isgenerallyassumedknowledgeinlaterExaminations.

PartIA

This Examination, taken at the end of the secondyear, comprises three general papers coveringaspectsof thesubjectcovered in the first twoyearsof the course; the results are carried forward to betaken into account togetherwith Parts IB and II todetermine your final degree classification. Part IAmustnormallybe satbeforePart IB, andnot in thesame year. Part IA is weighted 15% in the finalclassification.

PartIB

PartIBconsistsofsixgeneralpaperscoveringallthecore material in the course and one options paperwith a wide choice of options. At the end of thisExamination candidates are divided into thosejudgedworthyofHonours(whocanproceedtoPartII, but who may leave, if they wish, with anunclassified BA Honours Degree), those passing(whocannotproceedbutwhogetaBAPassDegree),andthosefailing.PartIBisweighted50%inthefinalclassificationattheendofPartII.

PartII

This is a research year, culminating in presentationofathesisandaviva(oralexamination),followedbyclassificationandawardoftheM.ChemDegree.PartIIisweighted25%inthefinalclassification.

The oral Examinations will be usually held in 10thand11thweekofTrinityTerm.Themainpurposeofthe viva is to assure the Examiners that you havecarried out and understood the work described inthe thesis, but you may be asked more general

questionsrelatingtoyourproject.Thevivamayalsoprovide an opportunity for you to clarify points inyourthesisthatwereuncleartotheExaminers.

Theabovenotessummarisethemainpoints,butareneitherauthoritativenorcomplete;thedetailedandauthoritative regulations are contained in theExaminationRegulationsoftheUniversity

http://www.admin.ox.ac.uk/examregs/andthe

ExaminationConventionsbelow.Incasesofdifficultyconsult the Senior Tutor of your College. TheProctors are the ultimate authority for interpretingtheRegulationsatthedetailedlevel.

Appropriate allowances and arrangements may bemade for medical or other special circumstancesaffecting Examination performance. Senior Tutorswilladviseandassist;butcandidatesarenotallowedto communicate directly with the Examinersthemselves.

Candidates who have a year out for any reason(permissionandarrangements for thisareamatterforColleges)arenotdisadvantagedinanyway.

Written Examinations are marked anonymously,candidates are identifiedbynumberonly; atPart IIanyExaminerwhoknowsacandidatepersonallywillneitherexaminetheirthesisnorconducttheirviva.

For the conventions regarding marking and theweighting of the various parts see ExaminationConventions in Chemistry below, any changes madeafter theprintingof thisbookmaybe foundon thewebversionhttp://teaching.chem.ox.ac.uk/

Each Board of Examiners is nominated by a smallcommitteewithin thedepartment,andapprovedbythe MPLS (Division). The Board of Examiners isformallyappointedbytheUniversity.

Once appointed, the Examiners operate as a bodysharing responsibility with considerable discretionwithin guidelines set by the Regulations and theChemistry Academic Board (CAB), but the Proctorsare the ultimate authority on everything exceptacademicjudgement.

Thecurrentsetofexaminersandthemembersofthenominating committee may be found athttps://intranet.chem.ox.ac.uk/committee-members.aspx

SeeAppendix B for informationabout the typesofcalculators that may be used in writtenExaminations.

ForsyllabusesseetherelevantAppendices.

MostCollegessetinformalexaminationsoftheirowncalled 'Collections',usuallyat thestartofeach term.They are formutualmonitoring of progress anddonotformpartoftheofficialUniversityassessmentatanystage.

ComplaintsProcedure

If your concern or complaint relates to teaching orother provision made by the faculty/department,then you should raise it with the Associate Head(teaching)(Dr.N.J.B.Green)orhisdeputy(TBA).Theofficer concerned will attempt to resolve yourconcern/complaint informally. General areas ofconcern about provision affecting students as awhole should be raised through Chemists’ JointConsultativeCommittee(CJCC).

If you are dissatisfied with the outcome, you maytake your concern further by making a formalcomplaint to the Proctors under the UniversityStudentComplaintsProcedure

(https://www.ox.ac.uk/students/academic/complaints).

On the role of the Proctors and Assessor, see theirEssentialInformationforStudents,onthewebat

http://www.admin.ox.ac.uk/proctors/info/pam/index.shtml

If your concern or complaint relates to teaching orother provision made by your college, you shouldraise it either with your tutor or with one of thecollegeofficers/SeniorTutor.Yourcollegewillalso

be able to explain how to take your complaintfurtherifyouaredissatisfiedwiththeoutcomeofitsconsideration. Further information on thecomplaints procedure is on the web athttp://teaching.chem.ox.ac.uk/.

Academicappeals

Anacademicappealisanappealagainstthedecisionof an academic body (e.g. boards of examiners,transferandconfirmationdecisionsetc.),ongroundssuchasproceduralerrororevidenceofbias.Thereisnorightofappealagainstacademicjudgement.

If you have any concerns about your assessmentprocess or outcome it is advisable to discuss thesefirst informally with your subject or college tutor,Senior Tutor, course director, director of studies,supervisororcollegeordepartmentaladministratoras appropriate. They will be able to explain theassessmentprocessthatwasundertakenandmaybeable toaddressyourconcerns.Queriesmustnotberaiseddirectlywiththeexaminers.

If you still have concerns you can make a formalappeal to the Proctors who will consider appealsunder the University Academic Appeals Procedure(https://www.ox.ac.uk/students/academic/complaints).

ExaminationConventionsinChemistry

Introduction

These conventions have been approved by theChemistry Academic Board (CAB) and the MPLSDivision. They should be read together with thecurrentExaminationRegulations(availableonlineathttp://www.admin.ox.ac.uk/examregs/information/contents/) and the Undergraduate Course Handbook(http://teaching.chem.ox.ac.uk/Data/Sites/58/media/courseinfo/undergradhandbook2016.pdf). CABreviews the conventions, regulations andhandbookannually, and the Examination Conventionsmay besubject to minor adjustment during any academicyear. The Examiners have discretion to deviateslightly fromwhat is laid down,where appropriateandaccordingtocircumstances.

If any student or academic staff member finds anypart of the Regulations, Conventions or Handbookobscure, enquiries should be addressed to theChairman of CAB, through the Faculty office in thefirst instance (nina.jupp@chem.ox.ac.uk). Suchenquiries are welcome, as clarification helpseverybody.ItisnotappropriatetoaddressChairmenofExaminersonsuchmatters.

Detailsofthemembershipoftheexaminationboardscan be found at the following web address:https://intranet.chem.ox.ac.uk/committee-members.aspx. The Part IA, Part IB and Part IIboards each consist of 9 internal and 3 externalexaminers in addition to the chair. The Prelimsboard consists of 8 examiners, oneofwhom is also

chair.Candidatesmustnotcontactexaminersorthechaironexaminationmattersdirectlyunderanycircumstances.

Prelims

See especially the relevant part of the ExaminationRegulations:

(http://www.admin.ox.ac.uk/examregs/2016-17/pexaminchem/studentview/), but general reg-ulationsfoundelsewherealsoapply.

Each paper is set as a two and a half hour exam,except for the Organic Chemistry paper, whichwillbeathreehourexam.

Eachpaperwillbemarkedoutof100, according totheoutlinemarkingschemeprintedonthequestionpaper. Marks may be rescaled if necessary. AllPrelimpapershaveequalweightings.

Thepassmarkoneachpaperwillbe40.AfailmarkinMathematicsof38orhigherwillbeallowedasacompensated pass, provided that the candidatepasses all three Chemistry papers and has anaggregatemark on all four papers of 180 (45%) ormore. The aggregate will be the sum of all fouragreedmarks. NocompensationwillbeallowedonanyofthethreeChemistrypapers.

Distinctionsareusuallyawardedtocandidateswithan aggregate score of about 280 (70%) or higher,approximatelythetop30%ofcandidates.

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Except in special circumstances no candidate maypassPrelimswithouthavingcompletedsatisfactorilythe practical requirement. The first year practicalrequirementconsistsof11daysineachofthethreeteaching labs and a compulsory IT exercise,includinganintroductorydayineachlab.

A candidate who has failed in one or two subjectsmay offer those subjects at a subsequentexamination,andwillbedeemed tohavepassedallParts of Prelims if they pass these resitexaminations.

Acandidatewhohasfailed inthreeor foursubjectsmayretakePrelimsatasubsequentexamination,butmustofferallfoursubjectsandwillnotbedeemedtohave passed Prelims unless they pass all four resitexaminations.

The maximum number of attempts permitted atPrelimsistwo.

Progressionandclassification

No studentmay enter for Part IA unless they havealready passed all parts of Prelims. Prelimsmarksdonotcounttowardstheclassificationofthedegree.

Parts IAand IB, togetherwith the secondand thirdyear practical course and Part II, are conceived asparts of one examination, the Second PublicExamination.

There will be no pass/fail mark in Part IA; allcandidates who complete this Part of theexamination will have their marks carried forwardto Part IB, and candidates will not be permitted totakePart IAagain. PracticalworkwillnotbetakenintoaccountforPartIA.

AfterPartIBadecisionismadetoidentifythosewhoareworthyofHonours.Thisdecisionisbasedonanaggregate of Part IA and Part IB exam marks andmarks for the practical course with a relativeweighting of 15:50:10 respectively. The award ofHonours is also conditional on completion of theminimumpracticalrequirement.

The views of the External Examiners will beconsidered carefullybefore any candidate is deniedHonours. The honours threshold is expected to beabout40%. Studentsbelow thisborderlinemaybecalled for a viva voce examination with anexaminationboardnormally consisting of the ChairofExaminersandtheExternalExaminers.

Candidates who are judged not to be worthy ofhonours may not enter for Part II. The examinersmay recommend that they be awarded a B.A. PassDegreeorthattheyfailoutright.InrecentyearsthenumberofoutrightfailuresinPartIhasbeen0or1andthenumberofPassdegreesawardedhasbeen0-2 (total candidate numberswere of the order 150-190).

Candidates who are judged worthy of honours butwhodonotwishtocontinuetoPartIImaygraduatewithanunclassifiedB.A.Honoursdegree.

The final degree classification for those worthy ofhonoursdependsonperformanceinPartsIA,IB,thepractical course and Part II together, weighted15:50:10:25respectively.

PartsIAandIB

SeeExaminationRegulations,

(http://www.admin.ox.ac.uk/examregs/2016-17/hschoofchem/studentview/), but general reg-ulationsfoundelsewherealsoapply.

PartIAconsistsofthreeGeneralPapers,andistakenattheendofyeartwo.EachGeneralPaperissetasatwoandahalfhourexam,with10minutes readingtime, and students will be expected to attempt sixoutofeightquestions.

Part IB consists of six General Papers and oneOptionsPaper,andistakenattheendofyearthree.General Papers are three hour exams and studentswillbeexpectedtoattemptfouroutofsixquestions.Thelengthanddifficultyofthequestionswillbethesameaswhentheexamsweretwoandahalfhours,but candidateswillbegiven threehours toattemptthem, giving time for reading, reflection andreviewinganswers.Candidatesarediscouragedfromwasting the extra time by attempting additionalquestions.TheOptionsPaperisthreehours,plus10minutesreadingtime,andstudentswillbeexpectedtoattemptthreequestionsfromawidechoice.

All papers will be marked according to the outlinemarking scheme shownon the question paper. Themark scheme is a guide, and examiners have thediscretion to vary it if necessary. Marks may berescaled to ensure that they conform to theUniversity Standardised Mark (USM) scale. Themark will be reported as a percentage. The threeGeneral Papers in Part IA have equal weight, andcontribute 15% to the final degree classification.ThesixGeneralPapersinPartIBhaveequalweight,and contribute 42% towards the final degree. TheOptionspapercontributes8%.

Practicalcourse

Except in special circumstances, no candidate maypassPartIBwithouthavingcompletedsatisfactorilythesecondandthirdyearpracticalcourses,andtheIT practicals (a reduced third year course may beofferedifaSupplementarySubjecthasbeenpassed,asoutlinedbelow).

Thesecondyearpracticalcourseconsistsofastintof10 days (60 credit hours) in each of the threelaboratories.Thenormalthirdyearpracticalstint is12 days (72 credit hours), with a free choice ofexperiments across the three laboratories, plus thethird year IT practical. A candidate who has notcompletedthecorerequirementoutlinedabovemaystill qualify for a Pass Degree if they havesatisfactorily completed at least 20 days of thesecondandthirdyear laboratorycourse inadditionto the first year requirement and provided thathe/she satisfies the examiners in the Part IB

8

examination. Below this limit a candidate willautomaticallyfailPartIB.

Supplementarysubjects

ApassordistinctioninaSupplementarySubjectmaybe offered as an alternative to 6 days (36 credithours)ofthethirdyearpracticalrequirement.Whilethe majority of candidates who choose to take aSupplementary Subject will take a single courseduring their second year, a Supplementary Subjectmaybetakeninyears2,3,or4,withtheprovisothatamaximumofthreeSupplementarySubjectsmaybepassed. GoodmarksinSupplementarySubjectswillberecognisedbytheallocationofextracreditforthefinal assessment after Part II. For science basedsubjects this applies tomarksof 60%ormore, andformodernlanguagesamarkof70%ormore.

These bonus marks will be credited for eachSupplementary Subject passed at the appropriatelevel,butonlyoneSupplementarySubjectpassmaybeofferedinlieuofpracticalwork.Candidateswhoachieve a pass may not retake the sameSupplementarySubjectinasubsequentyear.

PartII

SeeExaminationRegulations:

(http://www.admin.ox.ac.uk/examregs/2016-17/hschoofchem/studentview/)

Part II is examined by Thesis and by viva voceexamination.TheChairmanofthePartIIExaminerswill circulate instructions on the preparation oftheses and information about other pertinentmatters in Hilary Term. Examiners may refuse toexamine a thesis if it fails to conform to theseinstructions.

TheseswillbereadbytwoExaminers,eachofwhomwill assignamarkoutof100. Becauseof thewiderange of subject matter in Part II projects it is notappropriate to prescribe a single marking scheme,buta setofguidelines forexaminers isavailableonthedepartmentalwebpageat

http://teaching.chem.ox.ac.uk/assessment-guidelines.aspx

The twoprincipal readersof the thesiswill alsoactasexaminersintheviva,whichwillbemarkedoutof20. ThesismarksmayonlybealteredfollowingthevivawiththeagreementofathirdexaminerandtheChair. Other than inexceptional circumstances, thevivacannotresultinadecreaseinthethesismarks.

ThepassmarkforPartIIshallbeanoverallscoreof40%(88/220).

Supervisorswillbeaskedtoreportontheworkofallcandidates and on any special difficulties oradvantagesthecandidatesmayhavehad.Nopartofthe Part II mark is given by the supervisor orallocatedtothesupervisor’sreport.

Supplementary Subjects may be taken during thePart IIyear, andmarkbonuseswillbeallocated for

goodperformance,asoutlinedpreviously.However,no retrospective compensation for shortfalls inpractical work or IT work reported to the Part IBexaminerswillbeallowed:candidateswhohavenotcompleted the practical requirement will not havebeen adjudged worthy of honours and will not bepermittedtostartthePartIIyear.

The two thesis marks and the viva mark will beaddedtogivethePartIImark.ThePartIImarkwillbe aggregated with the total (scaled) Part I markwithaweighting25:75,andexpressedasamarkoutof 1000. Bonuses for good performance inSupplementary Subjects will be added afteraggregation.

PartIIthesesmustbesubmittedtotheExaminationschoolsbeforethedeadlineofnoonontheFridayof7th week. Applications for late submission, forexample because of illness, must be made to theProctors. All unauthorised submissions after thedeadline will be reported to the Proctors forinvestigationofthereasonsforlatesubmission,andinadditiontoanysanctiontheProctorsmayimpose,an academic penalty will be applied to the Part IImarkatthediscretionoftheexaminers,accordingtothefollowingscheme.

Lateness Penaltymarks

Upto5pmontheFridayof7thweek 2.2(1%)

Up to 5 pm on the Monday of 8thweek

11(5%)

Up to 5 pm on the Tuesday of 8thweek

22(10%)

Upto5pmontheWednesdayof8thweek

44(20%)

UptonoonoftheFridayof8thweek 66(30%)

Morethanaweeklate Fail

Forexample,athesisgivenanoverallPartIImarkof141/220(64%)bytheexaminersonthebasisofthethesisandtheviva,butsubmittedontheMondayof8th week will be penalised 11 marks (5%) andawarded a final mark of 130/220 (59%). Anypenalty assessedwill be capped so that it does nottakethePartIImarkbelowthepassmark,40%,withthe exception of theses more than a week late.Candidates failing Part II remain entitled to theunclassifiedBAhonoursdegreetheyqualifiedforatPartIB.

Medicalcertificates

Medicalandothercertificateswillbeconsideredbythe Examination board for the set of examinationstheyapplytoandineachsubsequentyearuptoPartII. Most commonly, action will be taken when thecandidate’s full results are available after Part II.Medical certificates will also be considered forcandidates at the Pass/Fail or Pass/Honours

9

borderline after Part IB. Examination boards maytake account of medical and other certificatescovering a single paper by an appropriateadjustmentofthemarkorbydisregardingthatmarkindecidingaclassification.

Markingconventions

All written papers are marked according to anoutlinemarkingschemeprintedontheexaminationpaper. Examiners have discretion to vary thisschemeasnecessary. Paperswill eitherbedouble-marked or the marks checked against the markingschemebya secondexaminer. UniversityStandardMarks (USM)will be used for each paper, inwhichclassboundariesaredrawnatorcloseto70%,60%,50% and 40%, i.e. marks 70% and above are firstclass, marks between 60% and 70% are 2.1, etc.Marks may be rescaled (see below). If scaling isused, detailswill be provided in the Chair’s report.AnyscalingofindividualpapersatPartIA,PartIBorPartIIwillbeappliedintheyeartheexaminationistaken.

Amarkofzeroshallbeawardedforanyquestionorpartsofquestionsthathavenotbeenansweredbyacandidate,butwhichshouldhavebeenanswered.

All parts of questions answered will be markedunlessclearlycrossedoutbythecandidate.Thebestsetofmarksconsistentwiththeexaminationrubricwill be taken, e.g. if the number of questionsspecifiedbytherubricis4andacandidateanswers5,thenthebest4markswillbetakenandthelowestmarkdiscarded.Studentsarestronglyadvisednottoattempt more questions than required: time spentdoinganextraquestion thatwillnotcount towardsthe total is time wasted. Any spare time is muchbetterspentincheckingandcorrectinganswers.

Errors may be carried forward at the discretion oftheexaminer,dependingonthenatureandseverityoftheerror.Similarly,partialcreditmaybegivenatthe discretion of the examiner for incorrect butreasonableanswers,particularlyiftheydemonstratethatthecandidateisthinkingthroughtheprobleminarationalway. Thesearebothmattersofacademicjudgement.

Discrepancies between the marks awarded bydifferent examiners will be resolved as follows.Marks will be averaged if they differ by less than10%ofthemaximumavailable,withathirdmarkerarbitrating if theydifferbymore than10%and themarkerscannotagree.

Practical marks will be awarded according to adetailed scheme that assesses the pre-lab, practicalskills,resultsandthewrite-up.Therelativeweightsof these components vary from experiment toexperiment.Practicalmarksmaybescaledtoensureuniformity of standard between experiments andmarkers. The final sign-off will be performed by aseniordemonstratororapprovedbya labmanager.Marks for practicals submitted formarking beyondthe 2-week deadline without good reason will becapped at 40%. Practicals submitted for marking

more than 4 weeks after the start without goodreasonwillbeawardedzeromarks.Practicalsmustbesubmittedformarking,andjudgedsatisfactory,inordertobecountedtowardsthePartIrequirement(252 or 216 credit hours, according to whether aSupplementarySubjecthasbeenpassed).

Unless there is very good reason, any student whofails to attend a timetabled or booked lab sessionandwhohasnotcontactedalabmanagerinadvanceto make alternative arrangements will receive amarks penalty of 50% for that session, even if thepracticaliscompletedatalaterdate.

The aggregate practicalmarkwill be reported as apercentage, and will be a weighted average of themarks for all the practicals that contribute to theappropriate requirement. The relative weight ofeach practical in this average will be advertised inthe laboratory manual. Detailed rules for thepractical course can be found on the website athttp://course.chem.ox.ac.uk/practicals.aspx

Scalingofexaminationmarks

It is university policy to awardUniversity StandardMarks (USMs) forexaminations, so thata first classperformancecorrespondstoamarkof70%ormore,an upper second class mark is between 60% and70%, a lower second classmark between 50% and60%andathirdclassmarkbetween40%and50%.Examinationmarksmay be scaled for any or all ofthefollowingreasons:

(a) a paper was easier or more difficult than inpreviousyears;

(b) an optionwasmore or less difficult than otheroptionstakenbystudentsinaparticularyear;

(c)apaperhasgeneratedaspreadofmarkswhichisnot a fair reflection of student performance on theUniversity’s standard scale for the expression ofagreedfinalmarks.

Scaling is not automatic. The decision aboutwhether to scale, the extent of the scaling and themethod of scalingwill bemade by the examinationboardaccordingtotheiracademicjudgement.

The choice of scaling method will depend on ananalysis of the examination scripts, the marksdistribution, marks obtained on the other paperstaken by the candidates in question, the historicalrecordandtheclassdescriptors. Forexample, ifanexaminationhasbeenharderthanexpected,andthishaspersistedacrossthewholeschool,asjudgedbyacumulative sum analysis, then a straightforwardlinearscalingmaybeselected. However, if thebestcandidates have been less affected by the problem,but the majority of candidates have found theexamination too hard, then regular scaling may beemployed. This isasingleparameterscaling,basedon the theory of regular solutions:

( )2exp (100 )y x x= α − .

10

Classification

The class borderlines will be drawn at or close to70%, 60%, 50% and 40%. The Examination Boardwill have the discretion to decide the exactborderlines, but they will not normally be higherthan these norms, nor more than 1% lower. Eachpaper will contribute the following proportions tothemaximumaggregatemark:

EachPartIApaper 5%

EachPartIBGeneralpaper 7%

PartIBOptionpaper 8%

PartIPracticalcourse 10%

PartII 25%

It is expected that the percentages of the classesawardedwill be in the rangesof recent years, i.e. I,33-42%;IIi,42-50%;IIii,10-15%;III,0-5%. Theserangesarenotmandatory:occasionallyacandidate’sthesisandvivaaredeemedinadequateforanyclassofM.Chem.degree. Suchcandidates remainentitledtotheunclassifiedB.A.HonoursdegreegainedafterPartIB.

ThefollowingQualitativeDescriptorsofClasseshavebeenadopted:-

Class General Markrange

Problems PartIIandessays

Class1 Excellent problem-solving skills andexcellentknowledgeofthe material over awide range of topics,and ability to use thatknowledge inunfamiliarcontexts.

90% -100%

Complete understanding,formulation correct, allsteps and assumptionsexplained properly.Technicallywithoutfault.

High degree of commitment tothe project. Clear evidence ofinitiative and independence.Excellent organisation, logicaldevelopment, thorough criticalanalysis of literature and data,excellentpresentation.

80% -90%

Excellent understanding,formulation correct, clearexplanations, very fewerrors.

Strong intellectual input intodesign and implementation ofproject. Excellent, original, wellwritten and structured. Criticalanalysisofdataandcommandofthe literature. High qualitypresentation.

70% -80%

Very good understanding,formulation correct,principal steps clear, anyerrorsareminor.

Clear evidence of intellectualinput and engagement withproject. Good understanding ofthe topic and the literature.Critical analysis of data. Wellwrittenandclearlystructured.

Class2.1

Good or very goodproblem-solving skills,andgoodorverygoodknowledge of much ofthe material over awiderangeoftopics.

60% -70%

Sound to goodunderstanding, principalsteps explained. Someerrors.

Evidence of some intellectualinput. Competent and coherentwriting. Good presentation,literature knowledge andanalysisofdata.

Class2.2

Basic problem-solvingskills and adequateknowledge of most ofthematerial.

50% -60%

Adequate understanding,not all steps explained andmaybe some gaps in logic.Some errors leading toincorrect or incompleteanswers.

Routine treatment of data,literature coverage may havegaps,writingcompetent,butlittlesign of critical thinking orintellectualinput.

Class3 Reasonableunderstanding of atleast part of the basic

40% -50%

Incomplete understandingand formulation. Stepsnotexplained, assumptionsnot

Shallow,narrowapproach. Poorunderstanding and little sign ofthought in selection of material

11

material and someproblem-solving skills.Althoughtheremaybea few good answers,the majority ofanswers will containerrors in calculationsand/or show in-complete under-standingofthetopics.

stated. Errors lead toimpossible answers. Lackofcriticalthought.

or structure of report.Conclusions may be lacking orflawed.

Pass Limited grasp of basicmaterial over arestricted range oftopics, but with largegaps inunderstanding.Thereneednotbeanygood quality answers,but there will beindications of somecompetence.

30% -40%

Limited understanding,large gaps. Some sign ofthought, but little actuallycorrect.

Little evidence of understandingorattempttoapproachthetopic.

Fail Inadequate grasp ofthebasicmaterial.Thework is likely to showmajormisunderstanding andconfusion, and/orinaccuratecalculations; theanswerstomostofthequestions attemptedare likely to befragmentaryonly.

<30% Inadequate understanding,fragmentaryanswers.

No engagementwith the project.Nosignofeffortorthought

TheinterpretationoftheseDescriptorsisatthediscretionoftheExaminers.Forproblemquestionsanswersmaybeverypatchy,excellentinsomeplacesanderroneousormissinginothers,itisthereforehardtoapplythesedescriptorstoproblems,althoughitshouldstillbeahelpfulchecklist.

12

FirstYear2016-17Lectures and Practicals The lecture timetable andinformation regarding practicals can be accessedfromtheChemistrywebpage:

http://teaching.chem.ox.ac.uk/.

ExperimentalChemistryistaughtinrotationateachof the three main departments. You will betimetabledasingleintroductorydayplustendaysineach of the three laboratories. The practical courseteaches essential experimental skills, from thesynthesis and characterisationof compounds to theoperation of spectrometers and other instrumentsfor physicochemical measurements. It makestangible much that is covered in lectures andtutorials. There is also an IT course concerningcomputer applications and chemistry softwarepackages(�approx.8hours).

The need to cope with large numbers of studentsmeans that you will go through the First Yearlaboratories on a rota system and you will bedesignated to a Group through your College.Attendance is compulsory, therefore please checkthe practical information web page:http://course.chem.ox.ac.uk/practicals.aspx

Strictdeadlinesforsubmissionoflaboratoryreportsmust be adhered to. Problems resulting in delay ofsubmissions should be reported to the responsiblepracticalcoordinatorattheearliestopportunity.Thefollowing people are responsible for the first yearpracticalcourses:

Organic:Dr.MalcolmStewartInorganic:Dr.VladKuznetsovPhysical:Dr.ZsuzsaMayerITPractical:Dr.KarlHarrisonTheywillwelcomeyour comments and suggestionsonthepracticalcourse.

Allpracticalworkmustbecompletedandmarkedoffby 5 pmon the Friday of 6thweek of Trinity Term.This is a University examination deadline and mayonlyberelaxedbypermissionof theProctors.Eachpractical is designed to teach you an importanttechnique,andyouwillnotbepermittedtoproceedto the second year unless the first year practical

coursehasbeensuccessfullycompleted.Ask for theDemonstrators’ advice over any problems that youmayhaveinthelaboratories.

Tutorials and Classes Most chemistry tutorials areorganised through your colleges, and classes willalso be offered in other subjects, particularlymathematics.YourCollegeTutorswillarrangethese.

ComputingThereisanareaofthewebsitecalled‘myDegree’ which produces online timetableinformation and practical booking, marking andcompletion information. The Department Web sitehttp://www.chem.ox.ac.uk provides a gateway to avastarrayofusefulinformation.Ifyouareinterestedin doing more computing, numerous courses areorganised at the IT Services, 13BanburyRoad, andinweek8ofTTyouwillbegivena short course inprogrammingusingPython.

e-mailPleasemakesureyoukeepyoure-mailboxesin good working order and delete old/unwantedmessagesasimportantinformationwillbecirculatedtoyouviae-mailfromtheFacultyOffice.Youshouldcheckyoure-maildaily.

Books Do not rush out immediately and buy newbooks as there are frequently second-hand booksadvertised on departmental notice boards for afraction of the cost. However, you are stronglyadvised tobuyonly the latesteditionof texts, sinceold editions areoftenout-of-date; Lecturersusuallyuse and give references to only the most recentedition. A list of the books recommended by theLecturers for the first-year course is given inAppendix A your Tutor will advise you as to whatbooksyoushouldobtain.

SocietiesTheChemistrySocietyholds regular socialfunctions, special interest lectures and otheractivities and is open to all chemistryundergraduates. You will receive informationdirectly from the officers of the Society. TheScientificSocietyalsoarrangestalksbydistinguishedvisitingspeakersonawidevarietyoftopics.

Refreshments Coffee and chocolate machines areavailableineachofthefoyersofthelaboratories.Asever, if in doubt, ask your College Tutor.

13

TheCourse

Chemistry lectures in the first year will provideintroductorycoverageofthefollowingtopics:

• physicalbasisofchemistry• quantumtheoryofatomsandmolecules• chemicalthermodynamics• reactionkinetics• equilibriumelectrochemistry• statesofmatter• atomicstructureandtheperiodictable• the ionic model, pre-transition metal

chemistryandsolidstatestructures• reactionsinsolution• introductorytransitionmetalchemistry

• chemical bonding and molecular orbitaltheory

• non-metalchemistry• introductiontoorganicchemistry• reactivityinorganicchemistry• introductiontoorganicspectroscopy• substitution and elimination at saturated

carbons• introductiontoorganicsynthesis• carbonylgroupchemistry• chemistryofC–Cπ-bonds• introductiontobiologicalchemistry

Formoredetail,seeAppendixD.

Examinations(Prelims)Seepage6.

ScheduleforFirstYearLectures

FormoredetailsseetheChemistryDepartment’sLecturewebpage

http://teaching.chem.ox.ac.uk/timetables.aspxM=MichaelmasTerm,H=HilaryTerm,T=TrinityTerm

Subject HoursperTerm M H TInorganicChemistry AtomicStructureandPeriodicTrends 6 IonicModelandStructuresofSolids 10 Molecular Shapes, Symmetry and Molecular OrbitalTheory 6

Acids,BasesandSolutionEquilibria 4 Non-metalChemistry 6 TransitionMetalChemistry 4Revisiontopics 4OrganicChemistry IntroductiontoOrganicChemistry 7 IntroductiontoOrganicSpectroscopy 2 OrbitalsandMechanisms 7 SubstitutionandEliminationofSaturatedCarbons 8 ChemistryofC–CπBonds 8 CoreCarbonylChemistry 8 IntroductiontoBiologicalChemistry 12RevisionCourse 4PhysicalChemistry FoundationsofPhysicalChemistry:ChemicalThermodynamics 13

ThePhysicalBasisofChemistry:Classicalmechanics 4

ThePhysicalBasisofChemistry:Propertyofgases 4 ThePhysicalBasisofChemistry:Theroleofchargel 4 ThePhysicalBasisofChemistry:TheroleofchargeII 4 QuantumTheoryofAtomsandMolecules 10 ReactionKinetics 6 Electrochemistry 4 StatesofMatter 4MathematicsforChemistry TheCalculusofOneandTwoVariables 20 IntroductiontoVectors 2 VectorAlgebraandDeterminants 6 Complex Numbers, Multiple Integrals and OrdinaryDifferentialEquations 10

MatrixAlgebra 8

14

SecondYear2016-17

TheCourseSome of the lectures develop further the topicsintroduced in the first year. There are additionallymanycoursesonessentiallynewtopics

• principlesofquantummechanics• symmetryanditsimplications• bondinginmolecules• solidstatechemistry• diffractionmethods• atomicandmolecularspectroscopy• statisticalmechanics• rateprocesses• valence• transitionmetalchemistry• coordinationchemistry• non-metalchemistry• organometallicchemistry• highenergyintermediates• chemistryofthelanthanidesandactinides• liquidsandsolutions• reactiveintermediatesinorganicchemistry• aromaticandheterocyclicchemistry• heteroatomchemistry• biologicalchemistry• organicsynthesis• physicalorganicchemistry• conformationalanalysisandringchemistry• mathsforchemists• organicspectroscopy

Practicals

Therewillbeanintroductorytalkatthebeginningofeach part of the course. Attendance is compulsory,thereforepleasecheckthepracticalinformationwebpage: http://course.chem.ox.ac.uk/practicals.aspx.YouwillgothroughthelaboratoriesonarotasystemandyouwillbedesignatedtoaGroupthroughyourCollege.

Strictdeadlinesforsubmissionoflaboratoryreportsmust be adhered to. Problems resulting in delay ofsubmissions should be reported to the practicalorganiserattheearliestopportunity.

Askforthedemonstrators’adviceoveranyproblemsthatyouhaveinthelaboratories.

Thefollowingpeopleareresponsibleforthesecondyearpracticalcourses:

OrganicPracticals:Dr.MalcolmStewartInorganicPracticals:Dr.VladKuznetsovPhysicalPracticals:Dr.ZsuzsaMayerITpractical:Dr.KarlHarrison

SupplementarySubjects

A number of Supplementary Subjects is availableeach year, on an optional basis; the titles will beadvertisedinthefinaltermofthepreviousyear.Forup to date information see the SupplementarySubjectpage:

http://course.chem.ox.ac.uk/supplementary-sub.aspx

Onofferfor2016-17are:

• QuantumChemistry• Aromatic, Heterocyclic and Pharmaceutical

Chemistry• ChemicalCrystallography• ChemicalPharmacology• ModernLanguages• HistoryandPhilosophyofScience

EachSupplementarySubjectExamination(allat theendofHilaryTermexceptforlanguageswhichissatinTrinityTerm)comprisesonepaper;whichresultsinfail/pass/distinction.APassgivesexemptionfromone year’s practical requirement in one laboratory(seepage8);amarkover60%inthesciencebasedsupplementary subjects, gives extra credit for thefinal assessment inPart II. Formodern languages amarkover70%givesextracredits.

AlthoughitisusualforSupplementarySubjectstobetakenintheSecondYear,theymaybetakeninanyofyears 2, 3 or 4, with a maximum of three in total.CandidateswhogetaPassmaynotretakethesameSupplementarySubjectExamination.

Formoredetail,seeAppendixE1.

Examination(PartIA)seepage7.

15

ScheduleforSecondYearLectures

FormoredetailsseetheChemistryDepartment’sLecturewebpage

(http://teaching.chem.ox.ac.uk/timetables.aspx).M=MichaelmasTerm,H=HilaryTerm,T=TrinityTerm

Subject Hours per

Term M H TInorganicChemistry Diffraction 4 TransitionMetalChemistry 6 BondinginMolecules 8 Co-ordinationChemistry 4 ChemistryoftheLanthanidesandActinides 4 OrganometallicChemistry 8 Electronicpropertiesofsolids 8 Periodictrendsinmain-groupChemistry 5NMRinInorganicChemistry 4Courseoverview 8RevisionTopics 2OrganicChemistry AromaticandHeterocyclicChemistry 4 OrganicSynthesisI 4 OrganicSpectroscopyI 6 ConformationalAnalysisandRingChemistry 10 PhysicalOrganicChemistry 8 RearrangementsandReactiveIntermediates 8 HeteroatomsinOrganicSynthesis 8 OrganicSynthesisII 8OrganicChemistryofBiomolecules 8ProblemSolving 2PhysicalChemistry QuantumMechanics:PrinciplesandApplications 12 LiquidsandSolutions 8 StatisticalMechanics 12 AtomicandMolecularSpectroscopy 10 Valence 8 RateProcesses 8RevisionLectures 3GeneralChemistry SymmetryI 5 SymmetryII 4 MathsforChemists 5 IntroductiontoNMR 4 SupplementarySubjects Aromatic, Heterocyclic and PharmaceuticalChemistry

16 14

QuantumChemistry 16 14 ChemicalCrystallography 12 9 HistoryandPhilosophyofScience 8 8 ChemicalPharmacology 4 14 ModernLanguage 32

16

ThirdYear2016-17

TheCourse

In the third year core course, the topics to becoveredare:

• posttransitionmetalchemistry• inorganicreactionmechanisms• bioinorganicchemistry• maingroupchemistry• solidstatechemistry• spectroscopyandmagnetism• organometallic reaction mechanisms and

catalysis• organicspectroscopy• pericyclicreactions• transition metal catalysis in organic

synthesis• radicalreactionsinorganicchemistry• curlyarrowsofbiology• strategiesinsynthesis• magneticresonance• photophysics&photochemistry• softcondensedmatter• physicalprinciplesofsolids• statisticalmechanics

Additionally 15 option courses are available aslisted in the “Schedule for 3rd year Lectures” below

and described in detail in the appendix. Theseoption courses will each comprise 8 lectures inHilary Term and 1 problem class in Trinity Term.The single, compulsory examination paper willcontain one question on the material taken fromeach of the 15 option courses. Candidates will berequiredtoansweratotalof3questionsin3hours.

PracticalWork

Before sitting Part IB, except in specialcircumstances,eachcandidatemusthavecompletedtheir practical requirement, which is a core secondyear requirement of 60 credit hours in eachlaboratoryplusathirdyearrequirementof72credithours plus the IT practicals; except that thosecandidates who take and pass a SupplementarySubjectwill have a reduced third year requirementof 36 credit hours plus the IT practicals. The thirdyear requirement is a free choice of third yearexperimentsofferedbythethreeteachinglabs,

Allpracticalworkmustbecompletedandmarkedoffby5pm,Friday,4thweekofTrinityTerm.

Formoredetail,seeAppendixE2.

Examination(PartIB)Seepage7.

ScheduleforThirdYearLectures

FormoredetailsseetheChemistryDepartment’sLecturewebpage:(http://teaching.chem.ox.ac.uk/)

M=MichaelmasTerm,H=HilaryTerm,T=TrinityTerm

Subject Hours perterm

M H TInorganicChemistry InorganicReactionMechanisms 4 Modernmaingroupchemistry 5 OrganometallicChemistry 5 SolidStateChemistry 5 Spectroscopy and Magnetism inInorganicChemistry

5

BioinorganicChemistry 4 Revision of Topics InorganicChemistry

6

ReviewofPeriodicTable 3OrganicChemistry AdvancedOrganicSpectroscopy 6 CurlyArrowsofBiology 4 OrganicSynthesisIII 8 TransitionMetalCatalysis 4 PericyclicReactions 6 RadicalReactions 4 RevisionLectures 4PhysicalChemistry PhysicalPrinciplesofSolids 8 SoftCondensedMatter 8 PhotophysicsandPhotochemistry 8

M H TOptionCourses MolecularSpectroscopy 8 1StructuralMethods 8 1Organometallic Chemistry:Structures,BondingandCatalysis

8 1

Solid State Compounds inTechnology

8 1

Supramolecular Nano andMedicinalInorganicChemistry

8 1

NaturalProductChemistry 8 1Advanced Synthesis and TotalSynthesis

8 1

ContemporaryMethodsinCatalysisforOrganicSynthesis

8 1

AdvancedChemicalBiology 8 1Functional Organic Polymers andMaterialsChemistry

8 1

Fundamentals of Atmospheric andAstrochemistry

8 1

MolecularReactionDynamics 8 1TheoreticalChemistry 8 1AnIntroductiontotheLiquidState 8 1MagneticResonance 8 1

17

FourthYear2016-17The fourth year is spent exclusively on research,providing you with the opportunity to immerseyourself in a significant project. A wide choice ofresearch projects is available in both pure andapplied Chemistry and also in related sciences. Youwill be supervised by a senior member of theacademic staff and have full access to the researchfacilities of your host laboratory. The year's workresults in a thesis, the assessment of which isweighted one quarter in the final determination oftheclassofM.Chemhonoursdegree.

Current researchnowspansahuge rangeof topics,many of which are interrelated. The students areencouraged to look at the web pages onhttp://www.chem.ox.ac.uk/researchthemes.asp andtoselect thearea theywishtowork inby followingthelinkstotheindividualmembersofacademicstaffworld wide web pages. Each page will contain arecent summary of their current research interestsand some have links to their own further researchinformation.Thiswillbe followedupbyOpenDaysusually held in Michaelmas Term. Each LaboratoryoffersanOpenDaywhereyouareinvitedtovisitthelabs,meetthesupervisorsanddiscusspotentialPartIIprojects.Youmaywish toreturn later for furtherdiscussion, but Open Days provide the idealopportunitytolearnabouttheresearchconductedin

Oxford.TherearepossibilitiesforPartIIstudentstocarry out a portion of the research project at aUniversityabroad.

Supplementary Subject courses (seehttp://course.chem.ox.ac.uk/supplementary-sub.aspx and Examinations are open to Part IIstudents.

For further information regarding the allocationprocess look at the web pages accessed from:http://teaching.chem.ox.ac.uk/.

Guidance for approaching the Part IImay be foundon the departmental web page fromhttp://teaching.chem.ox.ac.uk/.Detailedinstructionsto Part II candidates about the preparation andassessment of the thesis will be posted on theDepartmentalwebsitebythechairmanofexaminers,andnotifiedtoyoubye-mail.

ThereisaDataAnalysis lecturecoursedesignedforPart II students. There are also induction lecturesorganised on a Sectional basis and there areDepartmental Colloquia which Part II students areencouraged (indeed expected) to attend. These canbe found on the following web page:http://faculty.chem.ox.ac.uk/

PrizesAnumberofsubstantialPrizesandBursariesareavailable.In2016thefollowingwereawarded:

Bruker(UK)Ltd.forexcellenceinPrelims:totalof£300

SABMillerPlc.forexcellenceinPartIA:totalof£1,000

OUPBookPrize£150forthemostimprovedcandidate/sbetweenPrelimsandPartIA

GibbsPrizeinChemistryforexcellenceinPartIB:firstprize,proximeaccessitandthreebookprizestotalling£1,700

In addition therewere Thesis Prizes for excellence in Part II, and in practicalwork, and there are CollegePrizesaswell.

HistoryofAlchemyandChemistryPrize,inPartII,£150

18

AppendixA

RecommendedCoreTextbooksThefollowingwillbeuseful fromtheoutset,moredetailedrecommendationswillbemadebylecturersandtutors.

• PhysicalChemistry,Atkins,dePaula;OUP[10thedn.,2014].• InorganicChemistry,Weller,Overton,Rourke,,Armstrong,Atkins;OUP[6thed.2014].• ChemistryoftheElements,Greenwood&Earnshaw;Butterworth-Heinemann[2ndedn.],1997• FoundationsofOrganicChemistry,Hornby&Peach;OxfordChemistryPrimer,OUP,1997:• llustratededition2000• OrganicChemistry,Clayden,Greeves,Warren;OUP,[2nded.2012].• OrganicChemistry,MaitlandJones,Fleming;Norton[5thedn.2014]• AGuidetoMechanisminOrganicChemistry,Sykes;Pearson[6thedn.]1986• FoundationMathematicsforthePhysicalSciences,K.F.RileyandM.P.Hobson,Cambridge• UniversityPress,2011

AppendixB

CalculatorsforWrittenExaminationsinChemistryA candidatemay bring a pocket calculator into anyExamination,except thePrelimsMathematics forChemistrypaper,providedthecalculatormeetstheconditionssetoutasfollows:

The calculator must not require connection to anyexternalpowersupply

It must not be capable of communicating with anyotherdevice

It must not make a noise that could irritate ordistractothercandidates

It must not be capable of displaying functionsgraphically

Itmustnotbecapableofstoringanddisplayingtext,other than thenamesof standard functions suchas'sin'or'cosh'

Itmustnotbeabletostoreprogramsoruser-definedformulae

It must not be able to perform symbolic algebra,symbolicintegrationordifferentiation

Within the above, the calculatormay be capable ofevaluating elementarymathematical functions suchas sin(x), log(x), exp(x), xy and it may containconstantssuchasπ.

Notes

These guidelines follow the regulations but,supersede on detail, the 'Use of calculators inExaminations' in the University ExaminationRegulations.

Theintentionoftherulesistopreventthepossibilityof a candidate obtaining an advantage by having apowerful calculating aid (or of reading storedinformation as a substitute for knowing it). It isappreciated that candidates may already owncalculatorsthatareexcludedbytheserules. Insuchcase the candidate is responsible for obtaining amorebasiccalculatorthatiswithintherules,andforbecoming familiar with it in advance of theExamination.

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AppendixC

ImportantDatesDATESOFFULLTERM2016-17MICHAELMASTERM

Sunday9October-Saturday3December

HILARYTERM

Sunday15January-Saturday11March

TRINITYTERM

Sunday23April-Saturday17June

DATESOFFULLTERM2017-18MICHAELMASTERM

Sunday8October-Saturday2December

HILARYTERM

Sunday14January-Saturday10March

TRINITYTERM

Sunday22April-Saturday16June

DATESOFEXTENDEDTERMforPartIICandidatesinChemistry2016-17MICHAELMASTERM

Thursday22September-Tuesday20December

HILARYTERM

Tuesday3January-Wednesday12April

TRINITYTERM

Monday24April-Saturday8July

DATESOFEXTENDEDTERMforPartIICandidatesinChemistry2017-18MICHAELMASTERM

Thursday21September–Tuesday19December

HILARYTERM

Tuesday2January-Wednesday28March

TRINITYTERM

Monday9April-Saturday7July

ImportantdatesfortheDiary

Examinationentriesmustbemade throughyourCollege,whowilladviseyouof theappropriatedeadlines:detaileddates arenot available at the timeof printing, butmaybe foundon theuniversitywebpagehttp:http://www.ox.ac.uk/students/exams/timetables/ and more examination information can be found onhttp://teaching.chem.ox.ac.uk/examinations.aspx. . Students need to enter for optional examinations, i.e.Supplementary subjects and Prelims resits. All other entries will take place automatically. SpecialarrangementswillbemadeforChemistryPartIIbecauseoftheneedtoregistertheThesistitle.

SupplementarySubjectExaminations Begins8thweekHilaryTerm

(exceptModernLanguages) Tobetakenin8thweekTrinityTerm

Prelims Begins7thweekTrinityTerm

PartIAExamination Begins8thweekTrinityTerm

PartIBExamination Begins6thweekTrinityTerm

PartIIThesisdeadline 7thweek(Friday,12noon)TrinityTerm

PartIIVivas Begin10thweekTrinityTerm

Thesedatesareprovisionalandsubjecttochange

StudentsmayberequiredtobeinattendancebyColleges(PartIstudents)orSectionsandSupervisors(PartIIstudents)outsidetheFullTermandExtendedTermdatesgiven.

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AppendixD

SyllabusforPrelims2016-17

SUBJECT1,Chemistry1:Inorganic

Aims:Theaimofthefirstyearinorganicchemistrycourseistolayfoundationsintheareasofatomicstructure,bondingand the structures of molecules and solids, and chemicalreactivity. These areas and their importance will beillustrated by a wide-ranging descriptive chemistry of theelements.

AtomicStructureandPeriodicTrendsThe Bohr model, wave properties of electrons, the BornInterpretation:probabilitydensities.

The Schrödinger equation and the H atom. The quantumnumbersn,l,m1,theirvaluesandinterpretation(hence2s,3d, 4f, etc.) Shapes and energies of orbitals. Radialwavefunctionandtheradialdistributionfunction.

Polyelectronic atoms: Orbital approximation, sphericalaverage of electron repulsion. Helium and the PauliExclusion Principle: electron spin, antisymmetry.Screening and penetration, effective nuclear charge.StructureofthePeriodicTable:s-,p-,d-,f-blocks.Trendsinionisationenergies,electronaffinities,ionicradii,3dand4fcontractions.

IonicModel,Pre-TransitionMetalandSolidStateChemistryGeneral atomic and chemical properties of elements ofGroups 1, 2,within the framework of the Periodic Table.Elements, halides, hydrides, oxides. Born-Haber cycles,Born-LandéandKapustinskiiequation.Hess’sLawcycles.Trendsinthestabilityofbinarycompounds.Structuresofionic solids based on closed packing and filling ofinterstitialholes.Closepacking,unitcells,spaceefficiency.Fractional coordinates, plan views and projections.Location, number and size of octahedral and tetrahedralinterstitialholes.CommonABandAB2structures.Factorsaffectingstructure:relativesizes,charges,ionicity,vanderWaals,theNiAsclassofcompounds.Chemistryinaqueoussolution, trends in solubility of compounds, complexformation, nature of ligands and driving force. Chemistryin non-aqueous solution, metals in liquid ammonia,unusual oxidation states, organometallic chemistry (e.g.methyllithium).

Shapes,SymmetryandMolecularOrbitalTheoryLewis structures, VSEPR rules. Symmetry of molecules,symmetryelements,pointgroupdetermination.

Molecularorbital theory:H2+,H2, homonucleardiatomics,s/pmixing,bondstrengthandbondorder,paramagnetism.Heteronuclear diatomics, HF and CO. 3-centre-2-electron,3-centre-4-electronbonds:H3+,H3–HF2–,B2H6,XeF2.

Acids,BasesandSolutionEquilibriaDefinitions(Brønsted,Lewis),pKa,trendsinacidstrength,Pauling's rules for oxy-acids. Buffers. Redox potentials,Nernstequation,pHdependence,Latimerdiagrams,Frostdiagrams - constructionand interpretation.Calculationofequilibriumconstantsfromredoxpotentials.

Non-MetalChemistrySurvey of group trends. Electronegativity, size andpolarisability: implications for "ionic" compounds formedwith metals. Covalent bonds: trends in bond strength;formation of multiple bonds; hypervalence. Bonding

models for hypervalent compounds. Catenation andpolymerisation. Catenated andmultiple bonds with Si, P,and S. Polymeric structures formed by Si-O, P-N and S-Ncompounds.Boranes: structural classification andWade'srules;aspectsofpreparationandreactivity.

Donor/acceptor properties. Major trends in Lewisacid/base chemistry. HSAB classification. Ligandproperties.

High oxidation states. Group trends: the "Alternationeffect". Formation of polycations. Aspects of xenonchemistry.

TransitionMetalChemistryTransition elements and the Periodic Table. Survey ofatomic properties, oxidation states, energetics andcoordination environments. Key ideas of coordinationchemistry.Introductiontoligandfields.

SUBJECT2,Chemistry2:Organic

AknowledgeofthedynamicandevolvingscienceofOrganicChemistry is central to the discovery, understanding anddevelopment ofmany important breakthroughs in biology,medicine,andmaterialsscience.Thiscoursewillprovideanintroduction of the concepts and fundamental reactions ofOrganic Chemistry, show how these discoveries aresupported experimentally, and how this knowledge can beusedinaproblem-solvingandpredictivecapacity.

Aims:The course is designed to introduce and develop thefundamentalconceptsoforganicchemistry;toshowsomeofthe key experimental evidence which supports theseconcepts; to apply these data and concepts to chemicalproblemsolving.

IntroductiontoOrganicChemistryLewisbonding, bondpolarisation. Lewis acids. Structuresand isomers. Stereochemistry. Enantiomers: chirality,stereogenicity.Molecularorbitaltheoryhybridisation.

Functional groups: carbonyls, imines, oximes, nitriles.Lewis acids and bases. Curly arrows and mechanism.Resonance.

IntroductiontoOrganicSpectroscopyIntroductiontospectroscopy.Nuclearspinandresonance.Thechemical shift.Factors that influencecarbonchemicalshifts. Spin-spin coupling. Multiplet patterns for carbon-hydrogen couplings. Correlating carbon chemical shiftswithorganicstructures.

OrbitalsandMechanismsAcids and bases: resonance and inductive effects.Thermodynamics and kinetics. Hammond postulate. FMOinteractions.Conjugation;vinylogy.Reactions:curlyarrowrules, formal charges, mechanism and structure as aconsequenceofFMOinteractions.Solventeffects,reactiveintermediates:C–,C•,C+.

A unified approach to mechanism. Neutralisation andionisation, SN1. 1,2-Addition to C=O and β-elimination(E1cB, E2). SN2. Electrophilic addition with H+ &regiochemistry. E1. Electrophiles and stereospecificity.Attackbycarbenes,dienes=pericyclic.

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SubstitutionandEliminationatSaturatedCarbonsKinetics and mechanism of SN1 and SN2 reactions. MOtheory of substitution reactions. Stereoelectronics.Nucleophilicity and basicity. Activation of leaving groups.Carbocations. Substrates, leaving group, nucleophile andsolvent. Intermolecular substitutions giving alkyl halides,ethers, esters, amines, azides, thiols and sulfides,phosphonium salts. Substitution with nitriles/isonitriles.Intramolecularsubstitutionsgivingcyclicproducts.

KineticsofmechanismofE1andE2reactions,mechanismof E1cb reactions. MO theory of elimination.Stereoelectronics. Competition between substitution andelimination. Elimination for alkene and alkyne synthesis.E1cbincarbonylchemistry.

CoreCarbonylChemistryNucleophilic addition to C=O, reversible and irreversible.Nucleophilic substitution of C=O, (acetals; imines, oximesand hydrazones; enamines, Wittig and Horner-Emmonsreactions, Wolff-Kishner reaction). Nucleophilicsubstitution at C=O, (acid chlorides; anhydrides; esters;amides). Simple IR stretch of C=O groups. Chemistry ofcarboxylicacids.

Keto-enoltautomerism:α-racemisationinacidorbase.pKaof simple FGs includingmalonates. Reactions of enolates.Alkylation,Claisencondensation,halogenationofketones.Thehaloform,ReformatskyandDarzensreactions.

Condensation reactions with carbonyl groups. The aldolreaction.Conjugateadditions.

ChemistryofC–Cπ -BondsAlkene and alkyne chemistry: influence of orbitals onreactivity.Overviewoftypesofreaction.Alkenereactivity:electrophilic addition, pericyclic addition, free radicaladdition,catalytichydrogenation.Allylicbromination.

Alkyne reactivity: electrophilic addition, hydration toketones, alkylation of terminal alkynes, reduction.Conjugation/delocalisation in non-aromatic systems:conjugated alkenes and alkynes, allenes. Modifications toreactivity,conjugateadditionreactions.

Structure and Reactivity of Aromatic compounds.Electrophilicaromaticsubstitution.Mechanism.Reactions:halogenation, nitration, sulfonation, Friedel-Craftsalkylation/acylation,formationofazodyes(couplingwithdiazonium salts). Directing effects. Nucleophilic aromaticsubstitution.Radicalreactionsatthebenzylicposition.

IntroductiontoBiologicalChemistry.Introduction, context and structure of a cell, highlightingmolecules that are important in biology. Amino acidstructure, chemistry and synthesis. Peptide structure,conformation and simple synthesis. Primary proteinstructure and sequencing, secondary, tertiary andquaternaryproteinstructure.

Introduction to the importance of enzymes in catalysingthediverse chemical reactionsof life; howenzymeactivesites enable catalysis including through the use ofcofactors; how enzymes achieve specificity in catalysis;introduction to transition state stabilisation and thethermodynamics of enzyme-catalysed reactions; a simpleenzymemechanism to illustratehow the conformationofaminoacidsidechainsenablesefficientcatalysis.

The chemical structure and fundamental properties ofnucleic acids and their building blocks; the nucleobasesthatoccur inDNAandRNA, theirphysicalproperties, theribose and deoxyribose sugars, nucleosides, nucleotides,andsinglestrandednucleicacids.

ThechemicalstructureofdoublestrandedDNA,A,B,andZ-DNA structures, how the structure of the double helixwas determined. Chargaff’s rules. Watson-Crick A.T andG.C base pairs, the importance of base stacking andhydrogen bonding in stabilising the double helix.Replication, involvementof dNTPs and the importanceofenzymatic control to ensureahigh levelof efficiencyandaccuracy.Basemispairingandthestructuresandphysicalpropertiesofmispairedbases.

SUBJECT3,Chemistry3:Physical

Aims: The first-year physical chemistry course laysfoundations in the key areas of quantum mechanics,physics, thermodynamicsand reactionkinetics,uponwhichthewholeofmodernphysicalchemistryisbased.

StatesofmatterandequilibriumThermodynamicsLe Chatelier’s principle. Equations of state. Systems andsurroundings.Workandheat.

First law. Internal energy. State functions. Expansionwork. Reversible and irreversible changes. Heat capacityandenthalpy.Thermochemistry.Standardstates.Standardenthalpy changes (transition, reaction, formation).Kirchhoff law. Second law. Direction of change. Entropy.Condition of equilibrium. Entropy changes of phasetransition. Temperature and pressure dependence ofentropy.Thirdlaw.Statisticalinterpretation.

Free energy. A and G. Available work. Temperature andpressuredependenceofGibbsenergy.

Phase equilibria. Clapeyron and Clausius-Clapeyronequations.One-componentphasediagrams.

Chemical equilibrium. Thermodynamics of mixtures.Chemicalpotential.Entropyandenthalpyofmixing.Extentof reaction. Reaction quotient. Condition for equilibrium,equilibrium constant and its temperature dependence;relationtostandardGibbsfunction.

ElectrochemistryThemetal/solutioninterface.Electrochemicalpotential.

Equilibrium Nernstian electrochemistry. Activity andactivity coefficients and their determination. Nernstequation. Cells and half cells. Reference electrodes.Reversibility and irreversibility of cells. Relation ofstandard potentials to thermodynamic quantities.Conductivityofionicsolutions- liquidjunctionpotentials.Measurementofstandardelectrodepotentials.

StatesofMatterMicroscopic view of structure and motion in the threestates; radial distribution function. Density, mechanicalproperties, diffusion and viscosity, degrees of freedom,equipartitionandheatcapacity.

Intermediatestatesofmatter:liquidcrystals,gels,glasses.

Intermolecular forces and pair potentials. Gas im-perfection, van der Waals equation, virial expansion.Relationshipbetweenpotentialenergycurveandthevirialcoefficients/internalenergy.

Single component phase diagrams (e.g., H2O, CO2, He);phasecoexistenceandstability, triplepoint,criticalpoint,multiplesolidphases.

QuantumMechanicsandSpectroscopyThephysicalbasisofChemistry:ElectromagnetismCoulomb’sLaw,electrostaticforcesandfieldsElectricenergyandpotential.

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Electricdipolemoment.Electriccurrent,resistanceandconductivity.Magneticforces–theLorentzforce.MagneticfieldsandtheBiot-Savartlaw.Magneticdipolesandmagneticmaterials.Waves,theE.M.spectrum.Superpositionanddiffraction.Refraction(Snell’sLaw).

QuantumtheoryofatomsandmoleculesQuantumtheory.Failuresofclassicalphysics.Quantizationofelectromagneticradiation.Wave-particleduality.ThedeBroglierelation.

The Schrödinger equation. Solution for particle in a one-dimensionalsquarewellandresults forann-dimensionalsquarewell;particleona ringand therigidrotor; simpleharmonic oscillator; hydrogen atom. Born interpretation.Correspondence principle. Zero point energy. QuantumTunnelling.

Eigenvalue equations. Position, momentum andHamiltonian operators. Expectation values, uncertaintyprinciple.

Atomic spectra: one-electron atoms and alkali metals.Orbitals, energy levels andquantumnumbers.Radial andangular distributions. Term and level symbols. Spin-orbitcoupling. Penetration and shielding. Selection rules andspectra.Structureofmany-electronatomsandtheAufbauprinciple.

KineticsThephysicalbasisofchemistry:ClassicalmechanicsandpropertiesofgasesNewton’s Laws of motion: forces, momentum andacceleration. Work, and kinetic and potential energy.Rotations: angular momentum and moments of inertia.Vibrations:simpleharmonicmotion.

Properties of gases: the perfect gas equation. Kinetictheory of gases, origin of pressure,Maxwell-Boltzmanndistribution.

Molecularmotionsandequipartition.

Collisions between molecules, mean free path, collisionfrequency,effusion,diffusion.

ReactionkineticsRatesof reactions.Orderandmolecularity.Rate lawsandtheirdetermination.

Experimentalmeasurementofreactionrates.

Sequentialandreversiblereactions,pre-equilibrium,thesteady state approximation: applications to unimolecularreactions,enzymecatalysis,andchainreactions.

Temperature dependence of reaction rates: ArrheniusEquation,activationenergies,elementarycollisiontheory.

SUBJECT4,MathematicsforChemistry

Calculators will not be permitted in the Examination butTables containing standard results from calculus andtrigonometrywillbeprovided.

SyllabusLinear equations and determinants. Vector algebra andcalculus, and applications to mechanics. Planepolar,spherical polar and cylindrical polar coordinates.Inverse functions. Hyperbolic functions. Limits and theirdetermination.

Elementary calculus of one and of two variables.TaylorseriesandL'Hopital'srule.Integration,integrationbyparts.Transformationofcoordinates.Theoryoferrors.MultipleIntegralsintwoandthreedimensions.

Complex Numbers. Argand diagram, Euler equation, deMoivre’stheorem.Solutionsoftheequationzm=a+ib

FirstOrderDifferentialEquations,exact,separable, linear,homogeneous.SecondorderLinearDifferentialEquations,linear homogeneous differential equations, equation ofharmonic motion, damping terms. Second order linearinhomogeneousdifferentialequations.Matrixadditionandmultiplication. Inverse matrices. Orthogonal matrices.Eigenvalues and eigenvectors. Properties of symmetricandofHermitianmatrices.

AppendixE1

SyllabusforPartIA2016-17

INORGANICCHEMISTRY

The content of the Part IA Examination in InorganicChemistry will be based on the content of the lecturesdelivered to 2nd year students. Candidates will also beexpectedtobefamiliarwithmaterialcoveredinthe1styearcourse.Insomequestionsitmaybenecessarytomakeuseofsimple symmetry arguments at the level covered in theSymmetry I and Symmetry II General Chemistry course.Candidateswillbeexpectedtobe familiarwiththecontentofthe1stand2ndyearpracticalcourses.

TransitionMetalChemistryAtomic properties. Relative energies of s and d orbitals.Electronic configurations. Ionisation energies. Zeff. Therelative stability of oxidation states. The ‘stability of thehalf-filled shell’. Sublimation energies of the elements.Heats of formation of cations. Trends in stability ofbinary compounds. Rationalisation of electrode

potentials. Ligand field splittings: high and low spincomplexes, spin-pairing energies; LFSE effects in latticeenergies, heats of formation, hydration energies, etc.; sitepreferenceenergiesinspinels.Dependenceonligandtype,oxidationstate,andtransitionmetalseries.

The Jahn-Teller effect and its consequences. Stability ofoxidation states in the 1st transition series. Trends inreduction potentials for M3+/M2+(aq). Oxidation state(Frost)diagrams.

TheeffectofpHandofligandsonredoxpotentials.Factorsandligandsstabilisinghighandlowoxidationstates(egpiacceptorligandsversuspidonorligands).Roleofentropy.Main differences between the 1st and the 2nd and 3rdtransitionseries.Maindifferencesbetweenthe1standthe2ndand3rdtransitionseries:stabilityofoxidationstates;trends in covalence; metal-metal bonding. Highcoordination numbers. Comparative survey of thechemistry of transition metal groups, e.g. titanium,

23

zirconium and hafnium; chromium, molybdenum andtungsten; iron, ruthenium and osmium; nickel, palladiumandplatinum.

Introduction to transition metals in biology: iron andcopperinelectrontransferproteins,abriefsurveyofhaemironandcobaltenzymes.

Lanthanides&ActinidesLanthanides: Occurrence of the elements; electronicproperties: the nature of f-electrons; periodicity in the f-block.Extractionandseparation.Propertiesofthemetals.The predominance of the 3+ oxidation state. Structuralchemistry of the lanthanide compounds. Aqueouschemistry, complex formation, nature of ligands, redoxchemistry.Examinationofbinaryhalides,hydrides,oxidesand borides: structures and electronic properties.Organometallic chemistry. Comparisons/contrasts withtransitionmetals.Actinides:Occurrenceandpropertiesofthe metals. Periodicity and general chemistry of theactinides including comparisons with lanthanides andtransition series: oxidation states; aqueous chemistry;coordination stereochemistry. Focus on uraniumchemistry: halides, hydrides, oxides, aqueous chemistry(especiallyoftheuranylion),organometallicchemistry.

CoordinationChemistryThermodynamics and kinetics of complex formation:monodentatevspolydentateligands,includingacyclicandmacrocyclic examples. Isomerism (geometric, chiral).Thermodynamics of complex formation: stabilityconstants. Factors affecting the magnitude of stabilityconstants–IrvingWilliamsseries,chelateeffect,classaand class b classification, requirements of ligands.Macrocyclic Ligand Complexes: biological importance,macrocyclic effect. Concept of preorganisation.Macrocyclic ligand syntheses – template and non-template syntheses. Template effect: thermodynamicand kinetic contributions. Metal template synthesis ofinterlockedstructures.

BondinginMoleculesTheorbitalapproximation,theLCAOapproach.Theuseofsymmetry in polyatomicmoleculesMO treatment of AH2(linearandbent),AH3(planarandpyramidal),AH4(Td).

Walshdiagrams:TheshapesofAH2molecules,thebondingand shapes of H3+ and H3–: 3-centre-2-electron and 3-centre-4-electronbonds.

Photoelectron spectroscopy and "experimental" MOdiagrams,spectraofAHnmolecules.

AB2molecules from CO2 to XeF2, 12-electronmain groupoctahedral systems: SF6 as an example. 8-electron maingroup octahedral systems: [C(AuPR3)6]2+ as a relative ofCH62+.

Octahedral transition metal systems, α-bonding,comparison with electrostatic model. MO filling inoctahedral complexes: π-interactions and factors thataffect the magnitude of Δ . Molecular orbitals for 4-coordinategeometries:ML4(TdandD4h).

First-andsecond-orderJahn-Tellerdistortions.

OrganometallicChemistryGeneral principles: valence electron count, formaloxidation state, number of d-electrons. The 18- and 16-electron rules: applications and exceptions. Classificationof reactions: addition, dissociation, ligand substitution,migratory insertion, extrusion, oxidative addition,reductiveeliminationandattackoncoordinatedligands.

Synthesis, bonding and selected reactions: Transitionmetalalkyl,alkylidene(carbene),alkylidyne(carbyne)andcarbonyl complexes. Hydride, dinitrogen and dihydrogencomplexes. Alkene, alkyne and allyl complexes.Cyclopentadienyl, arene and other CnHn (n = 4 - 8)sandwichandhalf-sandwichcomplexes.Synergicbondingand π-complexes: CO as a ligand, alkene complexes,bondinginferrocene.

StructuresandElectronicpropertiesofsolidsDiffraction methods Distinction between lattices andstructures. Unit cells and Bravais lattices. Fractionalcoordinates.

Millerindices(hkl)and{hkl}.Calculationofdhkl.Derivationof Bragg's Law. Indexing powder diffraction patterns. X-raypowderdiffraction:techniquesanduses.Considerationof the peak intensity: the structure factor; systematicabsences. Use of powder diffraction for following solid-statereactions.

ElectronicpropertiesofsolidsModels of electronic structure: introduction to energybandsinionic,covalentandmetallicsolids.Bandgapsandtheirimportanceinthepropertiesofsolids.

Free Electron and Tight Binding models (treatedsomewhatmathematically).SimpleTightBindingpicturesfor elements such as: Li, Be, transition metals, diamondandSi,solidI2.Comparisonwiththemolecularpicture.

Extension of bandmodel to simple ionic compounds: e.g.NaClandCaO;transitionmetaloxides:TiO,ReO3,TiO2andVO2, and sulfides: ZrS2, NbS2, MoS2. Trends in theproperties of solids and how they relate to the generalchemistryofthetransitionmetalsinparticular.

BriefdescriptionofSpectroscopictechniquesforstudyingband structure. Mott-Hubbard insulators and breakdownof the bandmodel. Chemical trends in theMott-Hubbardtransition – competition between bandwidth andinterelectronrepulsion.

Low-dimensional metals and the Peierls distortion withexamples – electronically-driven structural distortions.Intrinsicandextrinsicsemiconductors;theeffectofdopinglevelontheproperties.

Structuresofsolids

Reviewofimportantstructuretypes;relationshipbetweencrystal structure and electronic structure – electronicstructure-directingeffectsandcomparisonwithmolecularsystems.

InorganicNMRMultinuclearNMR.Reviewof the fundamentals: chemicalshielding (diamagnetic & paramagnetic shielding terms)and scalar spin-spin coupling (multiplets, sequential stickdiagrams, coupling constant values, satellites). Structuresfrom NMR data (e.g. 19F NMR of main group fluorides).QuadrupolarNuclei.IntroductiontoNMRinthesolidstate.Dynamical processes and NMR: a range of examplesincluding trigonal bipyramidal molecules andorganometallicsystems.

Non-MetalChemistrySurvey of group trends. Electronegativity, size andpolarisability: implications for "ionic" compounds formedwith metals. Covalent bonds: trends in bond strength;formation of multiple bonds; hypervalence. Bondingmodels for hypervalent compounds. Catenation andpolymerisation. Catenated andmultiple bonds with Si, P,and S. Polymeric structures formed by Si-O, P-N and S-N

24

compounds.Boranes: structural classification andWade'srules;aspectsofpreparationandreactivity.

Donor/acceptor properties. Major trends in Lewisacid/base chemistry. HSAB classification. Ligandproperties.

High oxidation states. Group trends: the "Alternationeffect". Formation of polycations. Aspects of xenonchemistry.

ORGANICCHEMISTRY

The course is designed to develop the concepts of organicchemistry introduced in the first year; to show someof thekeyexperimentalevidencewhichsupportstheseconcepts;toapplythesedataandconceptstochemicalproblemsolving;andtodemonstratethatthesubjectisstillevolvingandthatit has a key role to play in modern technologicaldevelopments in diverse fields, ranging from chemicalsynthesis to biological science. Questions on the Part IAExaminationwillbebasedupon topicscoveredbyboth thefirst and second year lecture courses and in the practicalcourses.

Topicstobecoveredare:

OrganicSynthesisIA logical approach to synthesis illustrated by arene andcarbonyl chemistry. Retrosynthesis, disconnections, andsynthons. Order of events guided by functional groupcompatibility and selectivity principles; protecting andblocking groups. Carbon-carbon bond formation andfunctional group interconversion both separately and incombination. Synthesis ofmono- and 1,n-difunctionalisedmolecules.

OrganicSpectroscopyIIR spectroscopy. Vibrational transitions as a source ofbonding information; characteristic group frequencies;interpretationofspectra.

NMRSpectroscopy.Nuclear spinand resonance, chemicalshifts, factors that influence 1H chemical shifts. Spin-spincoupling, 1H coupling patterns and resonancemultiplicities, coupling to chemically equivalent spins,weak and strong coupling. Chemical and magneticequivalence; 1H spin couplings and chemical structure-geminal, vicinal and long-range couplings, chirality andNMR, chiral solvating agents. 13C NMR spectroscopy, 13Cchemicalshifts.

Mass Spectrometry. An introduction to MassSpectrometry; basic principles and applications;relationship between molecular weight and chemicalcomposition; processes of ion formation andinterpretation of a radical cation mass spectrum.Determining location of charge and predictingfragmentation patterns based on product ion stability.Interpreting fragmentation patterns for saturated andunsaturated aliphatics, aromatics and simple heteroatomcompounds. Examples. Application of all the abovespectroscopic techniques to the solution of structuralproblems.

AromaticandHeterocyclicChemistryThe nature and origin of aromaticity; the reactions ofaromatic compounds; the introduction of functionalgroups onto aromatic substrates; and the difference inreactivity of heteroaromatic compounds (furan, pyrrole,thiophene;pyridine;indole;quinoline;isoquinoline).

OrganicSynthesisProblemSolvingProblem-solving lectures relating to the 1st year course‘IntroductiontoOrganicSynthesis’.

ConformationalAnalysisandRingChemistryThis course examines the factors that controlconformationandreactivityinorganicmolecules,coveringstereoelectronic, steric, and electronic effects. Theconformationof acyclic andcyclicmolecules isdiscussed,and the concept of strain. Using this understanding, weanalyze how conformational and stereoelectronic effectsinfluencethereactivityandselectivityofreactionsofcyclicand acyclic organic molecules, focusing particularly onreactions of C=O and C=C functional groups. The coursealsocoversmethodsforringsynthesis.

PhysicalOrganicChemistryStructure and reactivity in organic chemical reactions.Kinetics,thermodynamics,transitionstates,intermediates.Rateequationsandkinetics,kineticisotopeeffects,solventeffects, linear free energy relationships, elucidatingreactionmechanism.Catalysisoforganicreactions.

RearrangementsandReactiveIntermediatesStructure, reactivity and rearrangement reactions ofcarbocations and carbanions. Neutral reactiveintermediates including carbenes, nitrenes and radicals,structure, synthesis, and reactivity. Rearrangements,including to electron deficient oxygen and nitrogen.Generalreactionsofradicals.

HeteroatomsinOrganicSynthesisThe chemistry of organic compounds containing boron,silicon, phosphorus and sulfur including their use in theconstruction of complex organic molecules andmechanisticandstereochemicalaspects.Briefextensiontootherelementse.g.Se.

OrganicSynthesisIIRegioselectivity, chemoselectivity, and stereoselectivity.Oxidation, reduction, selective alkene oxidation andreduction. Site blocking and protecting groups and theirutility;selectivecarbohydratemanipulationsasexemplars.Principlesofretrosyntheticanalysisandworkedexamples.

OrganicChemistryofBiomoleculesChemical synthesis of nucleic acids: solid-phasephosphoramidite DNA synthesis, synthesis of buildingblocks, synthesis of modifications that are commonlyintroduced into syntheticDNA for biological applications.Microarray DNA synthesis for the synthesis of entiregenomes. Solid-phase RNA synthesis: protecting groupstrategies. Large scale oligonucleotide synthesis fordiagnostic and therapeutic applications: backbone-modifiedDNAandDNAanalogues.Applications:antisenseoligonucleotides,exonskippingoligonucleotides,siRNA.

Enzyme kinetics; Michaelis-Menten model to determinesteady stateparameters, theuse of kinetic parameters tounderstand enzyme mechanisms, multi-substratereactions,reactionintermediates,othertoolstoinvestigateenzyme mechanisms, e.g. isotopes. Enzyme inhibition;pharmaceutical motivation, classes of enzyme inhibitorandmechanism of action, effects on enzyme kinetics anduse of kinetic data to identify potent inhibitors. Conceptswill be illustrated throughout with case studies,highlighting the contribution of enzyme structure tofunction.

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PHYSICALCHEMISTRY

The Examination will consist of questions relating to thelecture courses given in the second year, together with allthefirstyearmaterial:

QuantumTheoryOperators:basicnotionsandproperties; linearoperators,eigenvalue equations; degeneracy; expansion in acompleteset.

Postulates of QM and deductions therefrom; expectationvaluesandthemeaningofmeasurement inQM;thetime-dependentSchrödingerequation;stationarystatesandthetime-independentSchrödingerequation.

Commutators: definition, evaluation, properties. Physicalsignificanceofcommutators;complementaryobservables,simultaneous dispersion-free measurement and theuncertaintyprinciple(weakandstrong).Bra-ketnotation;definition and properties of Hermitian operators. One-body problems: the free particle (wave-particle duality;commutation and measurement; peculiarities). Theparticleinad-dimensionalbox(quantizationviaboundaryconditions; zero-point energy; the correspondenceprinciple; degeneracy). Rotational motion: angularmomentum; angular momentum operators, commutationrelationsandtheirsignificance;particleonaring;particleona sphereandeigenfunctionsofL2; the rigid rotor.TheH-atom. The simple harmonic oscillator: wavefunctions,energy levels and properties. The variational principle.Theexistenceofelectronspin.Spinfunctionsforasingleelectron. Spin functions for two electrons; singlet andtriplet states. The Pauli principle, antisymmetricwavefunctions, Slater determinants. Introduction toatomicspectra.Heatom:variationalcalculationofgroundstate 1s2; orbital approximation. 1s12s1 configuration;singletsandtriplets.Atomicstates:LScoupling;treatmentof spin-orbit coupling. The Zeeman effect in atoms(magnetic fields), g-factors. The Stark effect (electricfields).

LiquidsandSolutionsIdealsolutions:entropyofmixing,zeroenthalpyofmixing,Raoult’s law, idealsolubility,depressionof freezingpoint,osmotic pressure. Regular solutions: the effects of non-zero interactions, non-zero enthalpy of mixing, Henry’slaw,vapourpressure,phaseseparation.Polymersolutions:polymerdimensions insolution (thetaandgoodsolvents,radius of gyration), Flory-Huggins model, entropy andenthalpyofmixing,osmoticpressure.

Electrolyte solutions: activity coefficients of ions insolution, Debye-Hückel (D-H) theory, Debye-length, ionicstrength,applicationofD-H tosolubilityanddissociation.Surfaceofliquidsandsolutions:surfacetension,Laplace’slaw,theKelvinequation,theGibbsdividingsurfaceandtheGibbsadsorptionequations.

StatisticalMechanics.Systems of independent particles. Aims of statisticalmechanics. Distribution of molecules over molecularquantum states: microstates, configurations and theweightofaconfiguration.ThemostprobableconfigurationandderivationofBoltzmanndistribution for independentmolecules. Definition and significance of molecularpartition function,q. Factorization ofq into translational,rotational etc. components; calculation of qtrans and qelec.Determination of internal energy,E, and specific heat,Cv,from q; application to monatomic gas. Limitations ofMaxwell-Boltzmannstatistics.Meanvaluesofobservables;applications to bulk magnetization, paramagneticsusceptibility and derivation of Curie Law. Interacting

particles.Conceptofanensemble.Thecanonicalensembleand the canonical distribution. The canonical partitionfunction,Q, its physical significance anddeterminationofinternal energy fromQ. Entropy in statistical mechanics,anditsrelationtoQ.Determinationofenthalpy,Helmholtzfreeenergy,GibbsfreeenergyandchemicalpotentialfromQ.

IndependentparticlesII.ReductionofQforspecialcaseofindependent molecules: the relation of Q to q for (i)independent distinguishable and (ii) independentIndistinguishableparticles.

Summary of thermodynamic functions for independentparticles expressed in terms of q; separability ofthermodynamic functions into contributions fromdifferentmodes.

Calculation of molecular partition function and selectedapplications.qtrans,qelecandthestatisticalthermodynamicsof a monatomic gas; molar entropies and the Sackur-Tetrode equation. Rotational contribution to q forheteronuclear molecules; the high temperature limit andcharacteristic rotational temperature, θ rot. Rotationalcontributions to S and Cv. The effects of nuclear spin:symmetry numbers and qrot for homonuclear diatomicsand other symmetrical molecules. Applications torotational spectroscopy. Vibrational partition functions,qvib, for diatomic molecules and polyatomics. Chemicalequilibrium. Statistical mechanical result for theequilibrium constant K of a general chemical reaction.Calculating the equilibrium constant and selectedexamples: dissociation reactions, isotope exchangereactions, thermal ionization equilibria. Transition statetheory– thederivations.Conceptof the transitionstateand the reaction coordinate. Transition state theory interms of separable motion. The quasi equilibriumhypothesis.Derivationoftheexplicitexpressionfork(T)intermsofpartitionfunctions.

AtomicandMolecularSpectroscopyGeneral aspects of Spectroscopy: Energy levels ofmolecules; Born-Oppenheimer separation; the photon;interactionofradiationwithmatter;absorption;emission;transitionmoments;EinsteinCoefficients,selectionrules

AtomicSpectroscopy:RevisionofH-atom;wavefunctions;atomic orbitals; selection rules; Grotrian diagrams;Manyelectron atoms; Alkali metal (and pseudo-1-electron)atoms; Penetration and shielding; The quantum defect;Selection rules and spectra; Determination of ionisationenergies;RussellSaunderscoupling;Atomictermsymbols;TheHeliumatom;Singletandtripletstates;configurations,terms and levels; Hund’s rules; electron correlation;Effectsofexternalfields–Zeemaninteractions;spin-orbitcoupling;

MolecularSpectroscopy(General)

Molecular Rotational Spectroscopy; Rotors and theirsymmetry; revision of rigid rotor; moments of inertia;isotopeeffects;centrifugaldistortion;selectionrules;Starkeffect; Complications of nuclear spin statistics. MolecularVibrational Spectroscopy; Revision of harmonic oscillatorandselectionrules;Anharmonicity;normalvslocalmodes;symmetryconsiderations;vibrationrotationspectroscopy.

Molecular electronic spectroscopy; Potential energycurves/surfaces; Description of diatomic (linear)molecules;Classificationofelectronicstates;

Electronic selection rules; Franck-CondonPrinciple;Bandheads; Dissociation energies; Birge-Sponer extrapolation;Predissociation.

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RamanandRayleighScattering;rotationalandvibrationaltransitions; selection rules; mutual exclusion incentrosymmetricmolecules;Ramanvs.IR

ValenceBorn-OppenheimerApproximation;natureoftheproblemand the approximation; limitations in the Born-Oppenheimerapproximation.

Solving the electronicproblem:bonding inH2+; theLCAOapproximation.

Many electron molecules: the orbital approximation andits strengths and weaknesses; Pauli exclusion principle;binding of H2 and He2; splitting of degenerateconfigurations,dissociationofH2.

Applications of the variation principle: the LCAOapproximation and the secular equations; bonding inheteronucleardiatomics.

Bonding in the first row diatomic molecules: generalconsiderations;splittingintoterms(O2)andlevels(NO).

Walshdiagrams:bondanglesinAH2systems.

Hückeltheoryforpolyatomicmolecules:useofsymmetry;π-bondinginbutadienebondorder,electrondensitiesandorganicreactivity.

ApplicationsofHückeltheory:aromaticity;illustrationsofuseofperturbationtheory;correlationdiagrams.

RateProcessesSimple collision theory. Collision frequency and collisioncross section. Reaction cross section and steric factor.Potentialenergysurfaces.ClassicalmotionoverPES’s.Linkbetweenreactioncrosssectionsandrateconstants.

Transition state theory. Comparisonwith simple collisiontheory. Calculation of rate constants. Estimation of pre-exponential factors. Temperature dependence of rateconstants. Kinetic isotope effects. Quantum mechanicaltunnelling. Non-Arrhenius behaviour. Thermodynamicformulation of TST. Liquid-phase kinetics. Comparison ofliquid-phase and gas-phase reactions. Encounter pairs,cageeffect, andgeminaterecombination.Wavelengthandviscosity dependence of photodissociation, radicalscavenging, kinetics of I2 photodissociation, clusterreactions,spineffects.

Diffusion controlled reactions. Smoluchowski theory.Stokes-Einstein relation. Effects of solvent viscosity andtemperature, reactions between ions,spin effects.Activation controlled reactions. Gibbs energy of reaction,effect of electrostatic interactions, influence of solventpermittivity, entropy and volume of activation,electrostriction,influenceofpressureandionicstrength.

Electron transfer reactions. Marcus theory. Gibbs energyand reorganization energy. Marcus inverted region.Homogeneousandheterogeneouselectrontransfers.

Interfacial kinetics. Electric potential and its effect oninterfacialreactionrates.Butler-Volmerequation.Transfercoefficients.Overpotential.Tafelrelations.Voltammetry.

GENERALCHEMISTRY

SymmetryI-Molecularsymmetry,grouptheory,andchemicalbondingSymmetryoperations and symmetry elements. Symmetryclassification ofmolecules – point groups. Symmetry andphysicalproperties:Polarity,Chirality.

Combiningsymmetryoperations:‘groupmultiplication’

Mathematical definition of a group. Review of Matrices.Definitions, matrix algebra, inverse matrices anddeterminants. Transformation matrices. Matrixrepresentations of groups. Properties of matrixrepresentations. Similarity transforms. Characters ofrepresentations.

Reduction of representations. Irreducible representationsand symmetry species. Character tables. Orthogonalityrelationshipsingrouptheory.UsingtheLOTtodeterminethe irreps spanned by a basis. Symmetry adapted linearcombinations.

Bonding in diatomics. Bonding in polyatomics -constructingmolecularorbitalsfromSALCs.

SymmetryIICharacter tables and their meaning: C2v, C3v and Tdrevisited.

ThereductionformulaanditsapplicationtoSALCsinCH4.Projection operators and the SALCS of NH3. p orbitals inC6H6.

Another look at the origins of degeneracy in molecularsystems.Ligandfieldsplittingofdlevels.Tablesofdescentin symmetry. Jahn-Teller theorem. 2nd order Jahn Tellereffect.

Direct products - symmetry of many electron states.Selection rules in electronic spectroscopy: octahedralversustetrahedralsystems. IRandRamanselectionrules.Overtonesandcombinationbands.Vibronictransitions.

Vibrationalspectroscopy:stretchingvibrationsofCF4,SF4and XeF4. The mutual exclusion rule. Complete 3N basissetsandthevibrationsofNH3.ThevibrationsofC60.

MathsforChemistsOrdinarydifferentialequations:Seriessolution,Frobeniusmethod. Special functions: Bessel functions, Legendre,Laguerre,Hermitepolynomials.

Partialdifferential equations, separationof variables.TheSchrödingerequation;particlesinrectangularandcircularboxes, the H atom. The diffusion equation. Numericalmethods.Finitedifferenceand finite elementapproaches.Explicitandimplicitmethods.COMSOL.

Fourier series and Fourier transforms. FT infra-redspectroscopy and the Michelson interferometer. TheFellgettadvantage.

IntroductiontoNMRIntroduction to magnetic resonance, including thebackground physics of magnetic resonance, the origin ofshielding, multiplet structures, exchange phenomena andanoverviewofexperimentalmethods.

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APPENDIXE2

SyllabusforPartIB2016-17

INORGANICCHEMISTRY

GeneralPapers

TheexaminationpapersinPart1Bwillincludeallthetopicsconsidered in the core courses in Inorganic Chemistrydelivered in the 1st, 2nd and 3rd years of the course.Candidates should also be familiar with the materialcoveredinthepracticalcourse.Thestyleofquestionswillbesimilar to questions used recently in Part1B examinationpapers. For each paper, candidates will be required toanswer4questionstakenfromachoiceof6.

CoreLectureCoursesInorganicSpectroscopyandMagnetismElectronicspectraofmetalcomplexes

Thedifferenttypesofelectronictransition.Characteristicsof absorption bands: transition energy, intensity andbandwidth.

Selectionrules:allowedand forbiddentransitions.Ligandfield(d-d)spectra:trendsintheorbitalsplittingparameter(spectrochemical series); ligand field terms; Orgeldiagramsandspectralassignment.TheRacahparameterBandthenephelauxeticeffect.Tanabe-Suganodiagrams.

Charge-transfer (CT) spectra: (a) ligand-to-metal CTtransitions in tetrahalide, tetroxo and hexahalidecomplexes; the redox connection; (b) metal-to-ligand CTtransitionsinoctahedralML6.

Magneticpropertiesofmetalcomplexes.

Definitionofmagneticquantities.

Curie paramagnetism: the Curie law and the effectivemagnetic moment; the spin-only formula. Lanthanidecompounds: the Hund-Landé formula and its scope.Compounds of the transition elements: (a) quenching ofthe orbital magnetic moment; scope of the spin-onlyformula; (b) residual orbital angular momentum anddeviationsfromthespin-onlymagneticmoment.

BioinorganicChemistryIntroduction to bioinorganic chemistry: Cellularcompartmentalisation.TherolesoftheGroup1andGroup2 ions Na+, K+, Mg2+, Ca2+. Electrolytes, ion channels,signalling. Properties of complexes between metals andproteins–howoneinfluencesthechemistryofother.

Haem proteins and enzymes. Cytochrome c and electrontransfer.Thebiologicalchemistryofoxygen:haemoglobin,peroxidases, catalases, and monooxygenases. Oxygenbinding.Reactiveoxygenspeciesandoxidativedamage.

Cobalt and radical chemistry. The cobalamin co-factor.Cobalt oxidation states and their stabilization andchemistry.Mutasesandmethyltransferases.

The bioinorganic chemistry of proteins and enzymescontainingM–SandM–Oclusters.Iron-sulphurclustersinelectron transfer, nitrogen fixation, and hydrogenases.Manganese-oxochemistryandtheoxygen-evolvingcentre.

SolidsstatechemistryOverview of the material covered in the 2nd year: thebasicelectronicpropertiesofstoichiometricsolidsandtheeffectofintroducingdefects.

Defectsandiontransport

Stoichiometric defects: thermodynamic andstructural aspects. Ionic conductivity via defectmigration.Applicationsinbatteries,sensorsandfuelcells.

Non-stoichiometric defects: Thermodynamic equilibria.Structuralaccommodationofnon-stoichiometryinsolids-vacancies vs interstitials, ‘colour-centres’ and sheardefects.Electronicconsequencesofnon-stoichiometry.

Structures,ReactivityandSynthesis

Synthetic aspects of solid-state chemistry. Solid-statediffusionasthelimitingfactorforsolid-statereactivity.

High-temperature reactions performed underthermodynamic control: Precursor synthesis routes, co-precipitation, sol-gel synthesis. Flux and hydrothermalsynthesis.Solid-gasreactions.

Low-temperature reactions performed under kineticcontrol:intercalationreactions(graphite,C60,metaloxidesandsulphides);intercalation-deintercalationreactionsandapplications to lithium ion batteries; cation exchangereactions; anion intercalation and deintercalationreactions.

Superconductivity

Magnetic and electronic properties of superconductors.QualitativedescriptionofBCStheory.ChemicalaspectsofBCS superconductors – A3C60 and MgB2 as examples.Structural and chemical features of high-Tc cupratesuperconductors.Ironbasedsuperconductors.

ModernMainGroupChemistry"Traditional" conceptions of chemical behaviour in maingroup and transition metal systems. Moderninterpretationsofelectronicstructureandbondinginmaingroup compounds: Multiple bonding; Carbenes and theirheavieranalogues;Stablemaingroupradicals.

Novel modes of reactivity of main group systems:Frustrated Lewis Pairs; Small molecule activation usingsingletcarbenesandheaviergroup14carbeneanalogues;Reactivity of group 14 alkyne analogues. Catalysis usingmain group systems: Catalysis using Frustrated LewisPairs; "Redox" based catalysis using p-block elements -formal oxidative-additions, reductive eliminations;Catalysisusings-blockcomplexes.

InorganicReactionMechanismsLigand substitution reactions in square planar metalcomplexes (including the trans effect) and in octahedralmetal complexes: D, A, Ia, Id mechanisms, anation andsolvolysis reactions. Electron transfer reactions: innersphereandoutersphereelectrontransfer.IntroductiontoMarcus theory: interplay between donor-acceptoroverlap,thermodynamicdrivingforceandreorganisationenergy. Two-electron transfer and non-complementaryreactions.

OrganometallicReactionMechanismsandCatalysisOxidativeadditionand reductiveelimination.Mechanisticevidence including: dihydrogen compounds, agosticbonding.BriefmentionofC−Hbondactivation.

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α-andβ-hydrogentransfer;migratoryinsertionreactions.Introduction to homogeneous catalysis and aconsideration of various important and representativesystems.Includingtheisomerisationandhydrogenationofolefins; hydroformylation; Monsanto acetic acid process;Wacker process. Brief introduction to olefinpolymerizationbymetalloceneorsimilarsystems.

ORGANICCHEMISTRY

The course is designed to develop the concepts of organicchemistry introduced inthe firstandsecondyears; toshowsomeofthekeyexperimentalevidencewhichsupportstheseconcepts; to apply these data and concepts to chemicalproblem solving. The core course will provide acomprehensivetreatmentofmoreelaborateaspectsorganicchemistry, with an emphasis on synthesis and biologicalchemistry.

GeneralPapers

The examination paperswill be based upon topics coveredby the third year organic chemistry core lecture coursesbelow,andwillalso include topics covered in the first andsecondyearorganicchemistrylecturecoursesandpossiblyfrom the practical laboratory course. For each paper,candidates will be required to answer 4 questions takenfromachoiceof6.

AdvancedOrganicSpectroscopyNMR Spectroscopy: Assigning 1H NMR spectra: Spindecoupling and 2D NMR, 1H COSY; Assigning 13C NMRspectra: 13CNMRchemical shiftsand their interpretation,carbon spin coupling and spectrum editing (DEPT), 2DNMR-one-bond(HSQC)andmultiple-bond(HMBC)1H-13Ccorrelations.DefiningmolecularstereochemistryusingthenuclearOverhausereffect(NOE).

MassSpectrometry: Differences between radical cationandpseudomolecularionformation,stabilityandchemicaldetermination. Qualitative mass spectrometryanalysis:Chemical formulae calculation; nitrogen rule; highresolutionanalysis of isotopes signatures. Tandem massspectrometry: Post-sourcefragmentation processes;molecular and structural identification. Selectedapplicationsofmassspectrometry.

OrganicSynthesisIIIThe following questions will be addressed: Why do wewant to synthesisemolecules-what sort ofmolecules doweneedtomake?Whataspectsofselectivitydoweneedto exert to accomplish a good synthesis (think aboutchemo-, regio- and stereoselectivity, control of absolutestereo-chemistry).Whatistheperfectsynthesis?Whatarethe constraints imposed on an academic versus anindustrial synthesis? Where does chirality come from?Othertopicscovered include:Protectinggroupchemistry,which is central to almost any synthetic effort (includingthemajor typesofPGandtactics forprotectingmostandleast hindered functional groups). Retrosynthesis –learning to think backwards. Importance of making C-Cbonds and controlling oxidation state. Umpolung.Examplesofretrosynthesis/synthesisinaction.

For each case-study molecule, there will be a detailedretrosynthetic analysis and then a full discussion of thecompleted synthesis. Key points of interest in eachsynthesisaredescribed.

PericyclicReactionsHückel molecular orbitals; conservation of orbitalsymmetry; frontiermolecular orbital theory;Woodward-Hoffmann rules. Cycloaddition Reactions. Diels-Alder

reaction: endo-preference, Lewis acid catalysis; [2+2]cycloadditionofketenes,dipolarcycloaddition,cheletropicreactions; photochemical reactions. ElectrocyclicReactions. ring opening of cyclobutenes, ring closure ofhexatrienes, cyclopropyl halide solvolysis; chargedsystems. Sigmatropic Rearrangements. Dewar methodcomparedtoFMOapproach,[1,n]H-atomshifts,CopeandClaisen variants; ene reactions. Applications of pericyclicreactionsinsynthesis

TransitionMetalCatalysisIntroduction to organometallic chemistry of transitionmetals.Organopalladiumchemistry:Suzukicoupling,Heckcoupling and related cross couplings. Copper-catalysedcross-couplingreactions.Alkenemetathesis.

CurlyArrowsofBiologyAnIntroduction to the Chemistry of Metabolism/Bioenergy.Primaryandsecondarymetabolism.Glycolysisand the citric acid cycle. Amino acid metabolism andthenitrogencycle.

RadicalReactionsOccurrence and structure of free radicals; definitions;characteristic reactions. Free radical substitutionreactions; reactivity and regioselectivity. Kinetics andmechanism: addition to multiple bonds; selectivity andchain reactions. Kinetics and mechanism: rearrangementchemistry;kineticandthermodynamiccontrol.Radicalsinsynthesis: functional group chemistry; tandem, cascadeprocesses in complexity generation and application fornaturalproductsynthesis.

Revision –Molecular Structure and ReactivityThis courseprovides revision for essential knowledge of the organicchemistry course taken over the three years of theundergraduate course, considered under two broadheadings, molecular structure and molecular reactivity.Eachofthereactiontypeswillbeillustratedwithexamplesshowingtheirapplicationtosyntheticorganicchemistry.

PHYSICALCHEMISTRY

GeneralPapers

Candidateswillberequired toanswer4questionsoutof6.The style of questions on the two paperswill be similar tothatofthe2012-2016papersandofPartIBpapersintheyearsupto2011.

MagneticResonanceArevisionoftheprinciplesofNuclearMagneticResonance(NMR): magnetic moment, space quantization, theresonance condition, the vector model, populations andbulkmagnetization,selectionrules,theoriginofshielding,diamagnetic and paramagnetic shielding, neighbouringgroup anisotropy, ring current effects, electronic effects,intermolecular interactions. J-coupling,multiplet splitting,couplingtospinswithIgreaterthan½,discussionofFermicontact interaction, an introduction to dipolar coupling.Magnetic resonance spectroscopyof two coupled spin-½ particles: a quantum mechanical treatment. The rotatingframe, linear and circularly polarized fields, NMR as acoherence phenomenon; experimental methods:continuous wave and pulsed NMR, Free Induction Decay(FID) and Fourier Transformation for simple FIDs. Spinrelaxation: spin-lattice and spin-spin relaxation, therotational correlation time and the spectral densityfunction, spin relaxation and the vector model,measurement of relaxation times, the inversion recoveryexperiment,thespin-echoexperiment.

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SoftCondensedMatterInteraction between surfaces: dispersion forces; Van derWaals attraction; Hamaker constant; double layerrepulsion; measurements of forces. Surfactants: Gibbsadsorption equation; thermodynamics of micelleformation; geometric model for micelle shapes; interfacecurvature, wetting, capillarity. Colloidal phase behaviour;hard sphere crystallization; fluid-fluid phase separation;entropy driven phase transitions; polymers; elasticproperties of polymers; depletion interaction; polymerbrushes; Brownian motion; Langevin equation; Einstein-Smoluchowski equation; velocity auto-correlationfunction;diffusion;meansquaredisplacement;Timescales.

PhotophysicsandphotochemistryElectronic transitions of polyatomic molecules. Beer-Lambert law, selection rules and absorption strength,vibronic transitions, radiative lifetime, Franck-CondonPrinciple. Fates of excited states: Jablonski diagram,fluorescenceandphosphorescence,vibrational relaxation,intersystem crossing and internal conversion,Intramolecular vibrational redistribution,dissociation/predissociation. Lifetimes of excited states:quantum yield, photochemical kinetics, fluorescence /phosphorescence quenching, Stern-Volmer plot.Intramolecular energy transfer: application of Fermi'sGoldenRule,ratesofintersystemcrossing(El-Sayedrule),and internal conversion, energy-gap law, isotope effects,conicalintersections.Delayedfluorescence.Intermolecularenergy transfer, Electronic energy transfer, long-range(dipolar, FRET) and short-range (exchange)mechanisms,spin correlation rules. Triplet annihilation. Tripletsensitizationanddelayedfluorescence.Exciplexformation.Chemical reactivity of electronically excited molecules;isomerisation, acidity, redox, orbital character etc. Therole of intersections in returning to the ground state.Geminate recombination, escape probability andrecombination timescale. Photoionisation andphotoelectron spectroscopy. Ion chemistry, ZEKE.Photodissociation,andpredissociation,ozonedestruction.Ultrafastphotochemistryandphotophysics.Pulsed lasers.Pump-probespectroscopy.Generationand fateofnuclearwavepackets.Chemistryinrealtime.

PhysicalPrinciplesofSolidsElectrons in solids: free electron gas in differingdimensionality, DOS and Fermi energy, electronic heatcapacity, Pauli paramagnetism, electrical conductivity,Wiedemann-Franzlaw,deficienciesinfreeelectronmodel.Phonons in solids: Einstein theory of heat capacity,deficiencies, Debye model, optical and acoustic phonons,thermalconductivityininsulators.

Defects and disorder in solids: Classification of defects,thermal population of point defects, Schottky heatcapacity, theoryof theorder-disorder transition inalloys.Surfaces: structure of surfaces, types of adsorption,LangmuirandBETisotherms,dissociativeandcompetitiveadsorption,heterogeneouscatalysis,heatofadsorption.

OptionsPaper

The option courses are designed to develop advancedconcepts andmethods in chemistry to cover some areas ofcontemporaryinterest,forexampleintechnologyandintheenvironment.Theoptionsaredynamic,andwillbeupdatedannuallytoreflectmoderndevelopments.ThecoursesareM(Masters level), assume knowledge of the core material inthefirstthreeyearsofthecourseandbuildonit.Theoptionsexamination will be three hours and students will beexpected toanswer threequestions.Eachof the16optionsoffered will have one 1-hour question on the paper. Each

option course comprises 8 lectures in Hilary Term and 1problemclassinTrinityterm.

AdvancedChemicalBiologyFunctional groups in proteins and nucleic acids. Peptidesynthesis:Methods,strategy,factorscompromisingyields,including loss of stereo-chemistry, and analysis. Use ofdifferent types of protectinggroups, coupling reagents(includinguseofprotein-splicingand,inoutline,enzymes)forsolidandsolutionphasepeptidesynthesis.Comparisonwithnucleicacidsynthesis,and,inoutline,withbiologicalpeptidebiosynthesis. Roles (in brief) and extent of post-translational modifications including enzyme catalyzedpeptide hydrolysis. Preparation and applications ofunnatural biopolymers prepared by mutagenesis andchemicalmethods.Conceptsinorthogonalchemistry.Useof reactions that do not occur in nature, e.g. selectedcycloadditions.

Synthesis of modified nucleic acids. Phosphoramiditereagents and post synthetic modifications.Phosphorothioates, dithioates, PNA and other DNAanalogues. Applications of modified oligonucleotides,fluorescentprobes–Taqman,MolecularBeacons,Forensicanalysis of DNA. Applicants of modified biopolymers:post-translation modification, spin labels, fluorescentprobes,etc.Florescentprobesasanexample.ChemistryofGFP,anaturalmodification.

AdvancedSynthesisandTotalSynthesisThis course builds from the core 3rd year lecture courseOrganic Synthesis III and will draw together many coresynthesistopics.Thecoursewillillustrateadvancesinthetotal synthesis of major classes of natural products,selectedpharmaceuticals,andotherchallengingmolecules,with asides to cover important reactions, reagents,reactivityandstrategyprinciples.

ContemporaryMethodsinCatalysisforOrganicSynthesisThelecturecoursewillfocusonnewmethodsofcatalysis,both organometallic and organocatalytic, applied toorganic synthesis. Sustainability (Green), industriallyrelevant chemistry, asymmetric syntheses, mechanisticstudies, and applications of key reactions will all beconsidered.

FunctionalOrganicPolymersandMaterialsChemistryDyes:Chromophores, commercial dyes, synthesis of azodyesandcyanines,directdyes,reactivedyesforcellulose,fluorescence, chemiluminescence, photochromics,photoinducedelectron-transfer.

Polymers:Polymerisation reactions: condensation vs.addition, step-growth vs. chain-growth, DP, Mn, Mw,polydispersity, Carothers equation, epoxy-resins, ringopening, stereochemistry, Ziegler Natta, metallocenecatalysts, living polymerisation (anionic, cationic, ringopeningmetathesis)architecture,dendrimers.

LivingPolymerisationand Conjugated Polymers: Livingfree-radical polymerisation (nitroxide-mediatedpolymerization, ATRP and RAFT). Approaches to thesynthesis of conjugated polymers, using polyacetylene,polyphenylene vinylene, poly-para-phenylene andpolythiopheneasexamples.

Liquid Crystals: classification: thermotropic/ lyotropic,calamitic/discotic, nematic/smectic/ columnar; examples;molecular structural requirements; synthesis; techniques:polarised optical microscopy, differential scanningcalorimetry; orientation: by electric fields, by rubbedsurfaces, by surfactants; twisted nematic LCD; LCthermometers; LC polymers:main-chain e.g. Kevlar, side-chain.

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OrganicSurfaceChemistry:Why is thereaneed tomodifysurfaces?Comparisonofdifferenttechniquesforpreparingand analysing organic surface functions: self-assembledmonolayers, chemical methods for surface modification,grafting to and grafting from, chemically activatedpolymers.

Organic Surface Chemistry: Post-polymerisationmodifications:physicalandchemicalmethods.Changes inmacroscopicbehaviour–wetting,biomoleculeandcellularadhesion.Dynamicsurfacesbehaviour.

OrganicElectronicMaterials: Types of organicmetals andsemiconductors: charge-transfer salts, conjugatedpolymers,molecularcrystals;bandstructure,solitonsandbipolarons; electroluminescence: how an LED works;photovoltaic devices: the basic principles, dye-sensitisedcells, polymer blend devices;controlling energy transferandelectrontransfer.

Fundamentals of Atmospheric and Astro-chemistryIntroduction to astrochemistry; spectroscopicmeasurementsonextraterrestrialenvironments;theearlyuniverse; synthesis of the elements in stars; cosmicabundance of the elements. The interstellar medium,molecular gas clouds and chemistry in interstellar space;ionization, gas-phase reaction, dust-grain chemistry, andneutralisation processes in interstellar gas clouds. Asimple model for the rate of ion-molecule reactions;chemicalmodellingofmolecularclouds.

IntroductiontotheEarth’satmosphere:verticalstructureof the atmosphere, pressure, composition, temperature;thehydrostaticequation;blackbodyradiation,absorptivityand emissivity, scattering and absorption of solarradiation; radiative balance and the green-house effect;role of boundary layer processes and clouds; photolysisrates.

Half-life, residence timeandrenewal timeofchemicals intheatmosphere, the importanceof trace species; sources,transformation, transport, and sinks of chemicals in thetroposphere; tropospheric chemical cycles; air pollution.The stratospheric ozone layer, catalytic cycles,perturbations to the ozone layer; polar ozone loss.Heterogeneous chemistry; aerosol concentration and sizedistribution, sources of aerosols, transformations,chemicalcomposition,atmosphericeffects.

Measurement methods for atmospheric sensing. Groundbased methods for minor constituents, absorption,scattering,fluorescence.

InorganicMolecularSpectroscopyHow various spectroscopic techniques are used tocharacterise inorganic systems. The complementarynatureofallthetechniqueswillbeillustrated.

Electronic spectroscopy –The use of spectroscopictechniques to probe transition metal and lanthanidesystems.

Vibrational spectroscopy – Underpinned by the course“Symmetry II”, but going further and demonstrating thevalue of matrix isolation, the use of polarised light andtimeresolvedstudiestoprobevarioussystems.

NMRspectroscopy-ExamplesofapplicationsofarangeofNMRmethods includingdoubleresonance techniques,2DNMR, cross polarization and magic angle spinning NMR.Use of NMR to study dynamic systems including theextraction of quantitative data, mechanistic informationandrealtimeNMRstudies.

AnIntroductiontotheLiquidStateClassicalstatisticalmechanics:classicalpartitionfunction,phasespace;pairwiseadditivity,secondvirialcoefficient.

Statisticalmechanics of the liquid state: pair distributionfunction, osmotic compressibility, Ornstein-Zernikeequation,structurefactor.

Light scattering: Rayleigh scattering (point scatterer),Rayleigh-Gans-Debyetheory(largerparticles),formfactor,Guinier and Porod's laws, structure factor and link tostatistical mechanics of liquids, partial structure factors,contrastvariation,computersimulationofliquids.

MagneticResonanceOverview of how modern NMR experiments work.Conceptual and theoretical tools needed to understandsomething of the inner workings of some of the moreimportant multi-pulse, multi-nuclear, multidimensionaltechniques used to probe the structures anddynamics ofmolecules.

Brief review of spin interactions in NMR. Zeemaninteraction, chemical shift. J-coupling. Energy levels.Appearanceofspectra.

Vector model. Magnetization. Rotating frame.Radiofrequency pulses. Free precession. T1 and T2relaxation. Free induction decay. Spin echoes, echomodulation. Fourier transformation, lineshapes. Productoperatorsforonespin.

Product operators for two coupled spins. Spin echoes,homonuclearandheteronuclear.

INEPT.Polarizationtransfer.Multiplequantumcoherence.Double quantum filter, INADEQUATE. Two-dimensionalNMR.COSY.NOESY.

Reviewofquantummechanicsofspinangularmomentum.SpinHamiltonian.

Density matrix. Time-dependent Schrödinger equation.Liouville-vonNeumannequation.Pulsesanddelays.Two-spinsystems.

MolecularReactionDynamicsIntroduction: Types of collisions: definitions of impactparameter,crosssections,differentialcrosssections,state-to-stateprocesses;conservationofenergyandmomentum.

Potential energy surfaces and trajectories: introduction topotential energy surfaces; types of potential energysurface;quasi-classical trajectoryandquantumscatteringcalculations as a link between experiment and theory;centrifugalbarriers.

Experimental techniques for control of initial states:spatial/temporalisolation;laserphotolysisandpumpandprobemethods;molecular beammethods, includingbriefexamplesofstate-selection,decelerationandorientation.

Experimentaltechniquesforprobingproductstates:crossedmolecular beams with mass spectrometric detection;chemiluminescence and laser induced fluorescence;resonantlyenhancedmultiphoton ionizationandRydbergtagging; velocity map ion-imaging; the lab to centre-of-massframetransformation.

Elastic and Inelastic scattering: total (integral) anddifferential cross sections; examples of molecular beaminelastic scattering experiments; types of energy transferandtheirrelationshiptointermolecularforces.

Reactive scattering: examples of crossed molecular beamreactive scattering experiments; reaction mechanisms,

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including stripping mechanism and the harpoon model,reboundreactions,andcomplexformation.

Controlling reagentsandcharacterizingproducts: effect oftranslational energy on the reaction cross-section forreactions with and without a barriers; effect of initialvibrational state on the reaction cross-section andPolanyi’s rules; selective disposal of energy, includingmicroscopic reversibility, and the potential energysurfaces for attractive and repulsive energy release;examples of mass effects and angular momentumconservationeffects;statisticalreactions.

Probing the transition state: examples of control ofmolecular orientation, stereochemistry and cone ofacceptance, angularmomentumpolarization; applicationsof femtochemistry; photoelectron detachmentspectroscopy.

NaturalProductChemistryThis course builds upon previous courses on primarymetabolism and synthesis and covers secondarymetabolism and biosynthesis of polyketides, fatty acids,terpenes,andalkaloids.Thetotalsynthesisofmembersofthese classes of natural product using a biomimeticapproach will be discussed. The course will include: thelink between primary and secondary metabolism;enzymes, cofactorsandcommonmetabolicpathways; theacetate hypothesis, fatty acid, prostaglandin andpolyketide biosynthesis; mevalonic acid formation,terpene, squalene and steroid biosynthesis; amino acidbiosynthesis; biosynthesis of alkaloids derived fromlysine/ornithineandphenylalanine/tyrosineleadingtothebiosynthesis of complex polycyclic alkaloids such asmorphine.

OrganometallicChemistry:Structures,BondingandCatalysisAnadvanced–leveloptionscoursethatwillcoverstructureand bonding in organometallic chemistry from anexperimental and theoretical viewpoint, and theapplication of organometallic compounds in variouscatalyticprocesses.

Homogeneousolefinpolymerisation

Homogeneous vs. heterogeneous olefin polymerisationcatalysts; examples of homogeneous transition metalcatalysts focussing on metallocene-types; co-catalysts:typesandmodeofoperation;polymerisationmechanism:initiation, propagation, termination; a-olefins and controloftacticity.

RingopeningPolymerisation

Introduction to synthesis of “green” polymers using ROPfocussingone-caprolactoneandlactide;examplesoftypesof catalyst (initiator); initiator and propagation bycoordination-insertion and activated monomermechanisms; transesterification processes; living andimmortalROP;controloftacticity.

E–Hsigmacomplexes:structureandbonding

Fundamentalissuesofelectronicstructureandbondinginsigmacomplexes featuringH-H,C-H, Si-HandB-Hbonds,relevance to oxidative addition chemistry, spectroscopicprobesofthenatureoftheinteractionwiththemetal.

C–Hactivation:Fundamentalsandcatalysis

C–H···Mbondsinorganometallicchemistry,abriefsurvey.C–Hactivationprocessesandtheirmechanisms.UseofC–H activation in synthesis. A discussion of representative

catalyticprocessesusingC–Hactivation,concentratingonmechanism.

Catalytic functionalisation of organic molecules by boranereagents.

Metal catalysed hydroboration and diboration of alkenesandalkynes,directborylationofC-halogenandC-Hbondsinarenesandalkanes.

SolidStateCompoundsinTechnologyThisbuildsonthecoretopicsofsolidstatechemistry.Thefocusisonpropertieswhichconfertechnologicalvalueonsolid state compounds (e.g. telecommunications, ICT,energygenerationandstorage).Forexample:

Materials for Energy applications. Photovoltaics, BatteryMaterials, Transparent Conductors, Fuel Cell materials,Thermoelectricmaterials.Howdoweuseourknowledgeof Inorganic Chemistry to devise new compounds withparticularproperties?

Superconductivity. Classical and non-BCS super-conductors. Factors affecting Tc. Recent developments;superconductorsinaction.

Magnetism.Thecollectivemagnetisminsolids.Theusesofmagnetic materials in technology – magnetoresistance,multiferroicmaterials.

StructuralMethodsThefocusisonusingvariousstructuralmethodstoprobematerials in the solid state. The complementarity of thevarious techniques will be emphasised and moderninstrumentation will be described. 1. Diffractiontechniques – X-ray, neutron and electron diffractiontechniquesforcharacterisinglongrangeorderinextendedandmolecular solids. 2. Local Probes – EXAFS and X-rayabsorption techniques forelucidating local structure.Pairdistribution function analysis. Xray photoelectronspectroscopy for probing electronic structure. NMRspectroscopy

Supramolecular,NanoandMedicinalInorganicChemistryThis course focuses on specific examples of uses ofcoordinationcompounds.

Supramolecular Chemistry: nature of the non-covalentinteractions involved, illustrated with biological andsynthetic examples of cation, anion and neutral guestrecognition.Importanceofpreorganisationinhostdesign.ExtensionofTemplateEffecttoself-assembly,inparticularmetal-directedself-assemblyofpolymetallicarchitecturesdictatedbypolydentate liganddesignand stereochemicalpreference of metal. Catalysis within polymetallic cageframeworks. Anion coordination chemistry: biologicalimportance; exploiting electrostatics, hydrogen bondingandLewisAcidityinanionreceptordesignillustratedwithsynthetic examples. Simultaneous cation and anion (ion-pair)bindingbyheteroditopichostsystemsforextraction,salt solubilisation and membrane transport applications.Case studies will be discussed which highlight theprinciplesof transitionmetalopticalandredoxselectivesensing of cation and anion analytes of biological andenvironmentalimportance.

InorganicMedicinalChemistry:howinorganiccompoundsandcomplexescanbeusedtotreatanddiagnosedisease.For example: Therapy: platinum complexes in cancerchemotherapy, lithium carbonate, photodynamic therapyusing porphyrin complexes), radiotherapy (choice ofradioisotopes. Ligand design), targeted radiotherapy(bifunctional chelating agents, antibody and peptidetargeting,antibodydirectedprodrugtherapies).Diagnosis:

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Magnetic Resonance Imaging: principles of contrastimaging, development of paramagnetic contrast agents;factors influencing contrast agent design; targeted andresponsiveMRI imagingagents.RadioisotopeTomography(Positron Emission Tomography and Single PhotonComputer Tomography): blood pool and organ targetedimaging agents, application of bifunctional chelatingagents to targeted imaging of receptors. Luminescentimaging (responsive probes for endogenous metal ionsand anions): time-resolved imaging using lanthanidecomplexes, lanthanide based bioassay in drug discoveryanddiagnosis.Multi-modalimaging(MRI-PET,optical-PETandoptical-MRI).

Supramolecular cation and anion receptors and derivedoptical and redox sensors. Molecular machine design,examples of molecular switches and surface assembly.Multimodality in molecular imaging, nanoparticle imagecontrast and drug delivery systems. Supramolecularswitchesindrugdelivery.

TheoreticalChemistryTime-DependentQuantumMechanics

(1) Review of time dependence in quantum mechanics;stationaryandnon-stationarystates.Twolevelsysteminarotatingfield(e.g.,ESR/NMR),Rabioscillations.

(2) Perturbation theory: derivation of 1st orderamplitudes, application to two-level systems and acontinuous final spectrum (Fermi Golden rule rates).Applications of Fermi Golden rule rates to non-radiativeprocesses in molecules, e.g. inter-system crossing andinterconversion.

(3) The interaction of light and matter: dipoleapproximation, derivation of the Einstein A and Bcoefficients.DerivationoftheEinsteinAandBcoefficients.

(4)Conditionsforadiabaticandnon-adiabatictransitions,via the Landau-Zener theory, and application to asimplifiedtheoryofelectrontransfer.

StatisticalMechanics–Mean-fieldtheory

Recapofstatisticalmechanicsofnon-interactingsystems;consequences of interactions; role of theory, models andsimulation.Introductiontomean-fieldtheoryandconceptofmolecularfield.

Ferromagnetictoparamagnetictransition;Isingmodelanditsmean-fielddescription.

Liquid-gas phase transition; classical partition functions;mean-fieldderivationofvanderWaalsequationofstate.

APPENDIXE3

SyllabusforSupplementarySubjects2016-17

CHEMICALCRYSTALLOGRAPHY

A supplementary course exploring the way in whichcrystallography is used to determine the atomic scalestructure of chemical compounds covering crystalstructure, symmetry, diffraction, reciprocal space,experiments, structure solutions, modelling andrefinement.

1. Describing structure in real and reciprocal space.Understanding symmetry in diffraction patterns.Relationship between space group symmetry anddiffractionpatterns.

2. Space group symmetry notation and conventions.Lattices,symmetryoperationsandspacegroups.

3. Experimental considerations. Structure solutionmethods.Parameterisationofstructure.Obtainingthebestfit of amodel todata.Analysis and comparisonof crystalstructures.

QUANTUMCHEMISTRY

Timeindependentquantummechanics

Operators and Commutators. Postulates of quantummechanics; Linear operators; Hermitian operators; Theunit operator; Commutators; The uncertainty principle;Constantsofthemotion.

The Harmonic Oscillator. Hamiltonian. Creation andannihilation operators; Eigenvalues and eigenstates;Matrixelements.AngularMomentum.Angularmomentumoperators; Commutation relations; Raising and loweringoperators; Eigenvalues and eigenstates; Coupling ofangularmomenta.

Matrix Formulation. Matrix representations; Hermitianmatrices; Hamiltonian matrices; The variational method;Secularequations;Examples.

GroupTheory

Group Theory in the abstract: definition of a group,examples,multiplication tables,abeliangroups,conjugacyclasses. Symmetry and Quantum Mechanics: ‘true’symmetriesofthemolecularHamiltonian.Molecularpointgroups, Matrix representations and similaritytransformation, Reducible and Irreduciblerepresentations.

GreatandLittleOrthogonalitytheorems, includingresultsarising from them. Reduction of representations.Projection formula and SALCs. Direct Productrepresentations, Full Rotation Groups and Russell-Saunders coupling. Symmetry Properties of integrals andapplicationtoselectionrules.Applicationofgrouptheorytoelectronictransitionsandmolecularvibrations.

Perturbation Theory and Time Dependent QuantumMechanics

StationaryStatePerturbationTheory,Non-degenerateanddegenerate cases Applications, e.g. helium atom, StarkEffect,TimeDependenceinQuantumMechanicsEquationsofMotion,Time-independentHamiltonians,StationaryandNon-stationaryStates;Time-dependentHamiltonians

MolecularElectronicStructure

Introduction: Schrödinger equation, Born-Oppenheimer,wavefunctions; The linear combination of atomic orbitals(LCAO) approach to molecular orbitals; Pauli principle,Slater determinants Formulation of the Hamiltonian forH2+, H2. Matrix formulation and the secular determinants

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for a 1-electron system (H2+); Formulation ofH2 + in theLCAO approach; Formulation of Hamiltonian for H2. ;Coulomb integrals, Triplet state of H2 and the exchangeintegral,ExpansionoftheCoulombandexchangeintegralsinanatomicbasis,Self-consistentfieldsandHartree-Focktheory, Hartree-Fock and Roothaan equations, Basis sets,SlatersvsGaussians,Hierachyofbasissets,BeyondtheHFapproximation, Configuration interaction, Densityfunctional theory, Semi-empirical methods, Hückel andExtendedHückeltheory.

AROMATICANDHETEROCYCLICCHEMISTRY

Aromatic and heterocyclic chemistry is a very large andimportantbranchofchemistrywithwhichthosestudentswhoenterthechemicalindustryarealmostcertainlygoingto intimately involved. Mechanistic rationales for thesynthetic basis of aromatic chemistry that is practisedtoday will be presented; more descriptive organicchemistry than would be reasonable in a main lecturecourse will be given. The relationship of reactions inaromaticchemistrytothoseofaliphaticchemistrywillbeemphasised. This is an area that provides a substantialpart of the profits of the pharmaceutical industry, thesyntheses of some of the past and potential blockbusterswill be exemplified. The coursewill consist of 5moduleseachhaving5lecturesand1problemsclass.

HeterocyclicSynthesisI Objectivesofthecourse.Rangeof5ring heterocycles: synthesis of 1,4-dicarbonyls in manydifferentguises.Cheapnaturalsources.Fusedsystemsandinparticularindole.

Benzenoid Chemistry Comparison with heterocyclicreactions. Reactions of benzenoid systems: electrophilicaromatic substitution; early and late transition states;reactivity-selectivity in electrophilic and oxidative attack;electrophilic reactivity; ipso attack; kinetics versusthermodynamics; nucleophilic substitution; SNAr, SRN1,benzynemechanisms; applications in synthesis. Aromaticrearrangements.Arenemetallationsandcrosscouplings.

HeterocyclicSynthesis II Range of 6 ring heterocycles:1,5-dicarbonyls by aldol, base-catalysed dehydration andMichael reactions. Synthesis of frameworks with morethanoneheteroelementtowardspurinesandpyrimidines.

Reactions of Heterocycles - C=C versus C=O frameworks.Electrophilic attack easy on pyrroles and pyridines (atnitrogen). Dichotomies of electrophilic substitutionmechanisms. Mannich and Vilsmeier in aromatic andaliphatic systems. Decarboxylation and other ipsosubstitutions.Easyattackbynucleophiles - sometimesbyelectrophilic catalysis. Ring opening reactions. Differencefrombenzene.

Introduction toPharmaceuticalChemistry - Drug discoveryprocess: sildenafil. Physicochemical properties.Pharmacology: drug targets; potency; enzymes; receptors(cimetidine); transporters (omeprazole). Drug design:drug-protein Interactions; structure-based drug design(crizotinib). Pharmacokinetics: half-life, dose; volume ofdistribution (amlodipine and azithromycin); clearance.Drug safety: central nervous system; drug-druginteractions(ketoconazole,terfenadineandfexofenadine);anti-HIV(maraviroc).

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APPENDIXF

AcademicStaffAllStaffintheDepartmentcanbecontactedbye-mailwhichisgenerallythebestmethod.Addchem.ox.ac.uktothee-mailaddresseslistedbelow.

Name Section Office College e-mailAartsProfDGAL PTC PTCL ChristChurch dirk.aarts@AdlingtonProfRM OC CRL LMH robert.adlington@AldridgeProfS IC ICL Queen’s simon.aldridge@AndersonProfE OC CRL Jesus edward.anderson@AndersonProfHL OC CRL Keble harry.anderson@ArmstrongProfFA,FRS IC ICL St.John’s fraser.armstrong@BaldwinProfA PTC PTC Pembroke andrew.baldwin@BarfordProfW PTC PTCL Balliol william.barford@BattleProfPD IC ICL St.Catherine’s peter.battle@BayleyProfJHP CB CRL Hertford hagan.bayley@BeerProfPD IC CRL Wadham paul.beer@BeneschProfJLP PTC PTCL University justin.benesch@BrouardProfM PTC PTCL Jesus mark.brouard@BrownProfT PTC PTCL tom.brown@BurtonProfJW OC CRL Somerville jonathan.burton@ChippindaleDrA IC Pembroke ann.chippindale@ClaridgeProfTDW OC CRL tim.claridge@ClarkeProfSJ IC ICL Exeter simon.clarke@ClaryProfDC,FRS PTC PTC Magdalen david.clary@ComptonProfRG PTC PTCL StJohn’s richard.compton@ConwayProfSJ OC CRL StHugh’s stuart.conway@CooperProfRI IC CRL Pembroke richard.cooper@DavidProfW IC CRL bill.david@DaviesProfSG OC CRL Magdalen steve.davies@DavisProfBG OC CRL Pembroke ben.davis@DavisProfJJ IC PTCL ChristChurch jason.davis@DixonProfDJ OC CRL Wadham darren.dixon@DonohoeProfTJ OC CRL Magdalen timothy.donohoe@DoyeProfJPK PTC PTCL Queen’s jonathan.doye@DullensProfRPA PTC PTCL Lincoln roel.dullens@EdwardsProfPP,FRS IC ICL St.Catherine’s peter.edwards@FaulknerProfS IC ICL Keble stephen.faulkner@FlashmanDrE OC CRL emily.flashman@FletcherDrSP OC CRL stephen.fletcher@FoordProfJS PTC CRL StCatherine’s john.foord@GalpinDrM PTC PTCL martin.galpin@GildayDrLC IC IC St.Anne’s lydia.gilday@GoicoecheaProfJ IC IC LMH jose.goicoechea@GoodwinProfA IC St.Anne’s andrew.goodwin@GouverneurProfV OC CRL Merton veronique.gouverneur@GreenDrNJB PTC ICL nicholas.green@HarrisonDrK IC PTCL karl.harrison@HaywardProfMA IC ICL Somerville michael.hayward@HeazlewoodDrB IC CRL brianna.heazlewood@HillDrC PTC PTCL Somerville christian.hill@HodgsonProfDM OC CRL Oriel david.hodgson@HoreProfPJ PTC PTCL CorpusChristi peter.hore@JacobsDrRMJ PTC CRL Magdalen robert.jacobs@KuznetsovDrV ICL ICL vladimir.kuznetsov@KukuraProfP PTC PTC Exeter philipp.kukura@LaidlawDrWM IC ICL Jesus michael.laidlaw@LeeDrV OC CRL victor.lee@LoganProfDE PTC PTCL University david.logan@

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McCullaghProfJ OC CRL james.mccullagh@McGradyProfJ IC PTCL New john.mcgrady@MackenzieProfSR PTC PTC Magdalen stuart.mackenzie@ManolopoulosProfDEDEMDE

PTC PTCL SEH david.manolopoulos@MoloneyProfMG PTC PTCL St.Peter’s mark.moloney@MountfordProfP IC CRL SEH philip.mountford@O’HareProfDM IC CRL Balliol dermot.ohare@PatonProfR OC CRL St.Hilda’s robert.paton@PenfoldProfJ PTC PTCL j.penfold@rl.ac.ukPerkinProfS PTC PTCL Trinity susan.perkin@QuarrellDrREL OC Balliol rachel.quarrell@balliolReesDrNH IC ICL nick.rees@RennickDrC PTC PTC Pembroke chris.rennick@RitchieProfGAD PTC PTCL Worcester grant.ritchie@RobertsDrPM OC CRL St.Hilda’s paul.roberts@RobertsonProfJ OC CRL Brasenose jeremy.robertson@RobinsonProfCV PTC PTCL Exeter carol.robinson@RussellProfA OC CRL St.John’s angela.russell@SchofieldProfCJ OC/CB CRL Hertford christopher.schofield@SennDrM IC ICL mark.senn@SmithProfLJ CB CRL St.Hilda's lorna.smith@SmithProfMD OC CRL University martin.smith@StewartDrMI OC DP/T.Lab malcolm.stewart@ThompsonDrAL IC CRL amber.thompson@ThomsonDrJE OC CRL St.Catherine's james.thomson@TimmelProfCR IC ICL New christiane.timmel@TranterDrGE PTC CRL Merton george.tranter@Tsang,ProfSC IC CRL University edman.tsang@VallanceProfC PC PTCL Hertford claire.vallance@VincentProfK IC IC Jesus kylie.vincent@WellerProfAS IC CRL Magdalen andrew.weller@WillisProfMC OC CRL Lincoln michael.willis@WilsonProfM PTC PTC Brasenose mark.wilson@WongProfLL IC ICL St.Hugh's luet.wong@

PrincipalOfficials

HeadofMPLSDivision: ProfD.Bradley donal.bradley@mpls

HeadofDepartmentofChemistry: ProfM.Brouard mark.brouard@chem

AssociateHead(Teaching) DrN.J.B.Green nicholas.green@

AssociateHead(Research) ProfT.Brown tom.brown@

HeadsofSection: ProfS.FaulknerInorganicChemistry stephen.faulkner@

ProfC.J.SchofieldOrganicChemistry christopher.schofield@

ProfS.MackenziePhysicalChemistry stuart.mackenzie@

ProfJ.H.P.BayleyChemicalBiology hagan.bayley@

Chairman,ChemistryAcademicBoard Dr.N.J.B.Green nicholas.green@

Chairman,Chemists’JointConsultativeCommittee Dr.N.J.B.Green nicholas.green@

UndergraduateAdministrators MsN.Jupp,MrM.Shott nina.jupp@;mike.shott@

DisabilityContact MsN.Jupp nina.jupp@

Commonlyusedabbreviations:

OC=OrganicChemistryIC=InorganicChemistry

PTC=PhysicalandTheoreticalChemistryCB=ChemicalBiology

CRL=ChemistryResearchLaboratoryICL=InorganicChemistryLaboratory

PTCL=PhysicalandTheoreticalChemistryLaboratoryDP=DysonPerrinsBuildingT.Lab=TeachingLaboratory

MPLS=Mathematical,PhysicalandLifeSciencesDivision

36

APPENDIXG

UniversityPoliciesTheUniversityhasawiderangeofpoliciesandregulationsthatapplytostudents.Theseareeasilyaccessiblethrough the A-Z of University regulations, codes of conduct and policies available on the Oxford Studentswebsitewww.ox.ac.uk/students/academic/regulations/a-z

Toensurethattheseareuptodate,pleaseconsulttherelevantUniversitywebpages.

Intellectualproperty:http://www.admin.ox.ac.uk/researchsupport/ip/

Plagiarism:http://www.ox.ac.uk/students/academic/guidance/skills/plagiarism

Plagiarism is presenting someone else’s work or ideas as your own, with or without their consent, byincorporating it into your work without full acknowledgement. All published and unpublished material,whether in manuscript, printed or electronic form, is covered under this definition. Plagiarism may beintentional or reckless, or unintentional. Under the regulations for examinations, intentional or recklessplagiarismisadisciplinaryoffence

Equalopportunities:http://www.admin.ox.ac.uk/eop/

Disability:www.ox.ac.uk/students/welfare/disability

Harassment:http://www.admin.ox.ac.uk/eop/harassmentadvice/

Healthandsafety:http://www.admin.ox.ac.uk/safety/hs-mgement-policy/

ChemistryDepartmentsafety:http://safety.chem.ox.ac.uk/

Computerusage:http://www.ict.ox.ac.uk/oxford/rules/.

Examinationregulations:http://www.admin.ox.ac.uk/examregs/

TheProctors’Memorandum:http://www.admin.ox.ac.uk/proctors/info/pam/

DataProtectionAct1998:http://www.admin.ox.ac.uk/councilsec/dp/

OUSUStudentAdviceService-https://ousu.org/advice/student-advice-service/

Resources

UniversityCareersService:www.careers.ox.ac.uk

EnterprisingOxford:EnterprisingOxford:http://www.eship.ox.ac.uk/

Whatarethetopskillsneededtobeanexcellentresearcher?

Creativeproblem-solving?Resourcefulness?Confidenceanddetermination?Didyouknowthesearealsokeyattributesofanenterprisingorentrepreneurialmind-set?

Butwhatdoes“enterprising”actuallymean?If“Dragon’sDen”or“TheApprentice”isthefirstthingyouthinkabout,thencheckoutEnterprisingOxford,whereyouwillseewhatbeingenterprisingisandwhereitcantakeyou.

Enterprising Oxfordis an online map and guide to innovation and entrepreneurship in Oxfordshire,developedhere at theUniversity ofOxford. Start at the beginning,withEntrepreneurship 101, to discoverhowbeingentrepreneurialcanhelpwithresearchoremployability,orgostraightintoExplore&Buildyouridea.Readaboutentrepreneursatallstagesofthejourney,minglewithsuccessfulstart-ups,andfindcreativewaystofundyourideasandinitiatives.Whetheryouhaveanidea,astart-uporawellandtrulyestablishedventure,EnterprisingOxfordhighlightsopportunitiestodevelopfurtherorhelpsupportothers.

Commonly used abbreviations: PTCL = Physical and Theoretical Chemistry Lab. DP = Dyson Perrins Building ICL = Inorganic Chemistry Laboratory CRL = Chemistry Research Laboratory UM = University Museum RSL = Radcliffe Science Library