Department of Chemistry, College of Science, Sultan Qaboos … · 2015-10-21 · Name: Osama Kamal Abou-Zied Date of Birth: February 1967 Nationalities: American, Egyptian Marital

Curriculum Vitae

Department of Chemistry, College of Science, Sultan Qaboos University

P.O. Box 36, Postal Code 123, Muscat, Sultanate of Oman

Tel: (+968) 2414-1468 (Office); (+968) 9955-1937 (Mobile)

Fax: (+968) 2414-1469; Email: [email protected]

Personal Information

Name: Osama Kamal Abou-Zied

Date of Birth: February 1967

Nationalities: American, Egyptian

Marital Status: Married, two children

Education

Ph.D. Physical Chemistry

University of Saskatchewan, Canada (September 1995)

Dissertation Title: “A Study of the Electronic Spectroscopy and Vibrational

Dynamics of Jet-Cooled Azulene, Its Derivatives and van der Waals Clusters”

M.Sc. Physical/Inorganic Chemistry (course work)

Cairo University, Egypt (September 1990)

B.Sc. Chemistry

Cairo University, Egypt (honors with distinction) (May 1988)

Updated October 2015

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Employment Information

Title Institution Period

Professor Sultan Qaboos University May 2015 – present

Associate Professor Sultan Qaboos University May 2009 – May 2015

Assistant Professor Sultan Qaboos University Aug 2003 – May 2009

Muscat, Sultanate of Oman

Research Consultant Prima Pharm, Inc. Aug 2002 – Aug 2003

San Diego, CA, U.S.A.

Research Associate The Scripps Research Institute Aug 1999 – Aug 2003

San Diego, CA, U.S.A.

Postdoctoral Scholar California Institute of Technology Nov 1997 – July 1999

Pasadena, CA, U.S.A.

Postdoc. Res. Associate University of Illinois Oct 1996 – Oct 1997

Urbana-Champaign, IL, U.S.A.

Postdoctoral Fellow University of California Oct 1995 – Sep 1996

Riverside, CA, U.S.A.

Teaching Assistant University of Saskatchewan Sep 1991 – Sep 1995

Saskatoon, Saskatchewan, Canada

Demonstrator Cairo University Nov 1988 – Aug 1991

Cairo, Egypt

Awards and Fellowships

1. Best Researcher Award, University Day, College of Science, Sultan Qaboos University

(2013)

2. Best Researcher Award, College of Science annual retreat, Sultan Qaboos University

(2010, 2013)

3. Brain Gain Malaysia Recipient, Ministry of Science, Technology and Innovation

(MOSTI), University of Malaya, Malaysia (2009-2011)

4. Research Associate fellowship, The Scripps Research Institute, U.S.A. (1999-2002)

5. Visiting fellowship in Canadian government laboratories, NRC, Ottawa, Canada (1999)

6. Postdoctoral fellowship, California Institute of Technology, U.S.A. (1997-1999)

7. Postdoctoral Research Associate fellowship, University of Illinois, Urbana-Champaign,

U.S.A. (1996-1997)

8. Postdoctoral fellowship, University of California, Riverside, U.S.A. (1995-1996)

9. Herzberg award for best Ph.D. student in physical sciences, University of Saskatchewan,

Canada (1995)

10. Ph.D. scholarship, University of Saskatchewan, Canada (1991-1995)

11. Faculty of Science award for top graduate, Cairo University (1989)

12. First degree honor award, Department of Chemistry, Cairo University (1988)

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Teaching

Sultan Qaboos University (September 2003-present) Lecture Courses

CHEM 6631, Topics in Physical Chemistry (postgraduate-level course; Spectroscopy

and Dynamics in the Excited States with Biophysical Applications)

CHEM 5531, Physical Chemistry III (Photochemistry)

CHEM 4433, Physical Chemistry II (Molecular Spectroscopy)

CHEM 2102, General Chemistry II

Laboratory Courses CHEM 4435, Physical Chemistry II

CHEM 3335, Physical Chemistry I

CHEM 2107, General Chemistry for Medicine

CHEM 2102, General Chemistry II

CHEM 2101, General Chemistry I

Undergraduate Research Supervision Supervised 26 final-year B.Sc. projects

University of Malaya, Malaysia (June 2009)

Advanced Spectroscopy Series Course: Spectroscopy and Femtosecond Dynamics in the

Excited States

Postgraduate Supervision Ph.D. Supervision

Saba Sulaiman (started September 2013), Enhancing Drug Delivery Using Albumin-

Coated Nanoparticles: A Steady-State and Time-resolved Spectroscopic Study

Najla Al-Lawatia (degree awarded May 2013), Characterization of the Drug-Binding

Site Subdomain IIA of Human Serum Albumin Using Hydroxyquinolines as Molecular

Probes: A Combined Experimental and Theoretical Study

M.Sc. Supervision

Khadija Al-Maamari (started September 2015), Spectroscopy of Fluorescein in

Confined Nanocavities

Ghalia Al-Rasbi (degree awarded April 2012), Spectroscopy of Fisetin in Solution,

Confined Media, and in Protein

Badriya Al-Busaidi (degree awarded May 2010), Steady-State and Time-Resolved

Spectroscopy of Anthranilic Acid in Solution and in Human Serum Albumin Protein

Othman Al-Shihi (degree awarded June 2008), Using Small Probes to Study Human

Serum Albumin in Its Native, Unfolded and Refolded States

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Chair, Thesis Examining Committee Hilal Al-Shekaili (M.Sc., September 2011)

Thesis Examiner Salim Al-Habsi (M.Sc., August 2010)

Zulaikha Al-Harthi (M.Sc., September 2008)

Butheina Al-Haddabi (M.Sc., September 2007)

Thesis Committee Member Said Al-Faraji (Ph.D., September 2015)

Sami Al-Rashdi (M.Sc., September 2015)

Juwairiya Al-Shaqsi (M.Sc., February 2012)

Zakia Al-Mawali (M.Sc., September 2010)

International Co-Supervision Noor Idayu Zahid (Ph.D. degree awarded July 2013 (Department of Chemistry,

University of Malaya, Malaysia), Investigation of Glycolipids Self-Assemblies Using

Fluorescence Spectroscopy and Small-Angle X-Ray Scattering

Administrative Committees at Sultan Qaboos University

Chair, Post-Graduate Studies Committee (Chemistry)

Chair, Instructor Peer-Reviewing Committee (Chemistry)

Seminar Coordinator (Chemistry)

Time-Tabling Officer (Chemistry)

Exam Liaison Officer (Chemistry)

General Chemistry Committee

Academic Employment Committee (Chemistry)

Academic Promotions Committee (Chemistry)

Acting Head of Department (Chemistry)

Physical Chemistry Division Coordinator

Pre-Major Probation Committee (College)

Reviewer, The Research Council of Oman

Workshops and Conferences Organizing

Co-Chair, First SQU Chemistry Conference: Recent Trends in Drug Development (10-12

November 2015)

Member, Organizing Committee, Amber Workshop For Molecular Dynamics

Simulations (6-10 February 2010)

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Research/Professional Experience

Sultan Qaboos University, Oman (Aug 2003-present)

One of the challenging problems in physical chemistry is to understand protein-ligand

interaction at a molecular level and integrate this microscopic picture to explain chemical

processes in biology such as protein folding and unfolding, enzyme catalysis, and drug

binding and transport. We are particularly interested in studying protein-ligand binding

processes, local hydration, complex rigidity and conformation dynamics. Intrinsic probes,

such as the amino acid residues tryptophan and tyrosine, are characterized in various

biological systems in order to probe local electrostatic interactions. We also design and test

(in my group and through a network of international collaboration) novel probes that can

be used to understand certain chemical mechanisms inside DNA, lipids and proteins such

as proton transfer and tautomerization.

Techniques: We use various spectroscopic techniques in both energy and time domains.

We can resolve nanosecond dynamics using a time-resolved setup that is equipped with

laser and light-emitting diodes for different excitation wavelengths. A new femtosecond

laser lab was just completed in 2015 which enables us to resolve molecular dynamics in

the femtosecond time scale using fluorescence up-conversion and transient absorption

techniques. The experimental work is complemented by theoretical modeling (molecular

docking, molecular dynamics simulations, and ab initio/density functional theory

calculations) utilizing the High-Performance Computing facility at SQU.

Prima Pharm, Inc., San Diego, California, USA (Aug 2002-Aug 2003) Provided consulting services to the company regarding various chemical and

spectroscopic-related issues in pharmaceutical as well as skin care product development.

The Scripps Research Institute, San Diego, California, USA (Aug 1999-Aug 2003)

With Prof. Floyd E. Romesberg

Investigated the ultrafast photochemical proton transfer reactions of optical probes

incorporated in DNA duplexes. The research explored the storage and transfer of biological

information and the mechanism of DNA mutagenesis.

Techniques: Employed pump-probe technique based on the use of a femtosecond

Ti:sapphire laser coupled with optical parametric amplifier. Single-photon counting

technique was used to probe the dynamics in the picosecond-nanosecond time regime.

Molecular dynamics simulations were used to explain the results.

California Institute of Technology, Pasadena, California, USA (Nov 1997-July 1999)

With Prof. Ahmed H. Zewail

Studied the ultrafast dynamics of organic reactions that produce intermediate radicals. The

study analyzed and controlled certain radical reactions that cause air pollution as well as

disintegration of vital biological functions.

Techniques: Pump-probe technique was employed using a Nd:YAG laser and an Ar-ion

laser in order to produce femtosecond pulses of light by mode locking. The study was

carried out in the gas phase in supersonic-jet expansion. Ab initio calculations were used

to explain the results.

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University of Illinois, Urbana-Champaign, Illinois, USA (Oct 1996-Oct 1997)

With Prof. J. Douglas McDonald

Studied the mechanisms of photochemical reactions which play a crucial role in

atmospheric pollution.

Techniques: Pump-probe technique was employed using a Nd:YAG laser to produce sub-

picosecond pulses for excitation and probing the samples in supersonic-jet expansion.

Several models of calculations were used to fit and explain the results.

University of California, Riverside, California, USA (Oct 1995-Sep 1996)

With Prof. Gary W. Scott

Conducted spectroscopic investigations on organic photodimers imbedded in thin polymer

films to explore their suitability as substrates for optical information storage.

Techniques: An Excimer laser was used to provide the excitation light. Experiments were

performed at room temperature as well as at low temperatures, down to 77 K.

University of Saskatchewan, Canada (Sep 1991-Sep 1995)

With Prof. Ronald P. Steer (Ph.D. advisor)

Studied the spectroscopy and dynamics of solute-solvent interactions at a molecular level.

The study analyzed the role of solvation in changing the photochemical behavior of certain

organic molecules which may have useful applications.

Techniques: An Excimer laser and a Nd:YAG laser were used to provide the excitation

light at different wavelengths. Laser-induced fluorescence method was used to measure the

steady-state spectroscopic changes, and single-photon counting technique was used for

time-resolved study.

Cairo University, Egypt (Sep 1990-Aug 1991)

With Prof. Waheed Badawy

Started a project to study the electrochemical behavior of mammalian nervous tissue

extracts. The research examined the role of the presence of certain substances in the brain

in causing disorders that are related to Parkinson’s disease.

Techniques: Cyclic voltametry and current-potential measurements.

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List of Publications

*: corresponding author

Total number of citations: 935, h index = 16 (source: Scopus, October 2015)

Cumulative Impact Factor: 154.29

Highest single Impact Factor: 12.11

Largest number of citations for a single paper: more than 200 (published in 2008)

Since joining Sultan Qaboos University

2015 1. N.I. Zahid, O.K. Abou-Zied,* N.A.N. Saari, and R. Hashim

Comparative Study of the Inverse versus Normal Bicontinuous Cubic Phases of the β-D-

glucopyranoside Water-Driven Self Assemblies Using Fluorescent Probes

RSC Advances, under review, September 2015

Impact Factor: 3.84 (Royal Society of Chemistry), Q1

2. O.K. Abou-Zied,* N.I. Zahid, M.F. Khyasudeen, D.S. Giera, J.C. Thimm, R. Hashim

Detecting Local Heterogeneity and Ionization Ability in the Head Group Region of Different

Lipidic Phases Using Modified Fluorescent Probes

Scientific Reports, 2015, 5:8699, 1–9

Impact Factor: 5.58 (Nature Publishing Group), Q1

3. O.K. Abou-Zied* (invited review) Understanding the Physical and Chemical Nature of the Warfarin Drug Binding Site in Human

Serum Albumin: Experimental and Theoretical Studies

Current Pharmaceutical Design, 2015, 21, 1800–1816

Impact Factor: 3.45 (Bentham Science), Q1

4. M. Salim, O.K. Abou-Zied,* H.U. Kulathunga, A. Baskaran, U.R. Kuppusamy, and R. Hashim*

Alkyl Mono- and Di-Glucoside Sugar Vesicles as Potential Drug Deliveries: Detecting Drug

Release Using Fluorescence

RSC Advances, 2015, 5, 55536– 55543


5. O.K. Abou-Zied,* A. Barbour, N.A. Al-Sharji, and K. Philip*

Elucidating the Mechanism of Peptides Interaction with Membranes Using the Intrinsic

Fluorescence of Tryptophan: Perpendicular Penetration of Cecropin B-Like Peptides into

Pseudomonas Aeruginosa

RSC Advances, 2015, 5, 14214–14220


6. R.J. Abdel-Jalil,* T. Steinbrecher, T. Al-Harthy, A. Mahal, O.K. Abou-Zied, and W. Voelter

Stereoselective Synthesis and Molecular Modelling of Chiral Cyclopentanes

Carbohydrate Research, 2015, 5, 14214–14220

Impact Factor: 1.93 (Elsevier), Q2

7. S.A.J. Sulaiman and O.K. Abou-Zied*

Spectroscopic Characterization of the Binding Mechanism of Fluorescein and Carboxyfluorescein

in Human Serum Albumin

Proceedings of SPIE, The International Society for Optical Engineering, 2015, 9339, (8)1-10

8. N.I. Zahid,* O.K. Abou-Zied, and R. Hashim

Fluorescence Characterization of Water-Driven Self-Assembled Lipids and Their Temperature-

Induced Phase Transitions

Proceedings of SPIE, The International Society for Optical Engineering, 2015, 9339, (L)1-13

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9. O.K. Abou-Zied,* R. Hashim,* and B.A. Timimi

Amphitropic Liquid Crystal Phases from Polyhydroxy Sugar Surfactants: Fundamental Studies

Proceedings of SPIE, The International Society for Optical Engineering, 2015, 9338, (18)1-10

2014 10. O.K. Abou-Zied,* S.A.J. Sulaiman

Site-Specific Recognition of Fluorescein by Human Serum Albumin: A Steady-State and Time-

Resolved Spectroscopic Study

Dyes and Pigments, 2014, 110, 89–96


11. O.K. Abou-Zied,* J. Husband, N. Al-Lawatia, and T. B. Steinbrecher

Ground State Spectroscopy of Hydroxyquinolines: Evidence for the Formation of Protonated

Species in Water-Rich Dioxane/Water Mixtures

Physical Chemistry Chemical Physics, 2014, 16, 61–70


12. O.K. Abou-Zied,* B. Al-Busaidi, and J. Husband

Solvent Effect on Anthranilic Acid Spectroscopy

Journal of Physical Chemistry A, 2014, 18, 103–109

Impact Factor: 2.69 (American Chemical Society), Q2

2013 13. N.I. Zahid, O.K. Abou-Zied,* and R. Hashim

Evidence of Basic Medium in the Polar Nanochannels of the Inverse Bicontinuous Cubic Phase of

a Guerbet Glycolipid: A Steady-State and Time-Resolved Fluorescence Study

Journal of Physical Chemistry C, 2013, 117, 26636–26643


14. O.K. Abou-Zied* Spectroscopy of Hydroxyphenyl Benzazoles in Solution and Human Serum Albumin: Detecting

Flexibility, Specificity and High Affinity of the Warfarin Drug Binding Site

RSC Advances, 2013, 3, 8747–8755


15. O.K. Abou-Zied* Effect of NH2 Rotation on the Fluorescence of 2-Aminopurine in Solution

Journal of Photochemistry and Photobiology A: Chemistry, 2013, 261, 1–6


16. O.K. Abou-Zied,* N. Al-Lawatia, M. Elstner, and T. B. Steinbrecher*

Binding of Hydroxyquinoline Probes to Human Serum Albumin: Combining Molecular Modeling

and Förster's Resonance Energy Transfer Spectroscopy to Understand Flexible Ligand Binding

Journal of Physical Chemistry B, 2013, 117, 1062–1074


2012 17. O.K. Abou-Zied*

Revealing the Ionization Ability of Binding Site I in Human Serum Albumin Using 2-(2′-

Hydroxyphenyl)benzoxazole as a pH Sensitive Probe



18. N.I. Zahid, O.K. Abou-Zied,* R. Hashim, and T. Heidelberg

Fluorescence Probing of the Temperature-Induced Phase Transition in a Glycolipid Self-Assembly:

Hexagonal ↔ Micellar and Cubic ↔ Lamellar

Langmuir, 2012, 28, 4989–4995


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19. N. Al-Lawatia, T. Steinbrecher, and O.K. Abou-Zied*

Water Participation in Molecular Recognition and Protein-Ligand Association: Probing the Drug

Binding Site "Sudlow I" in Human Serum Albumin

Proceedings of SPIE, The International Society for Optical Engineering, 2012, 8233, (D)1–11

2011 20. N.I. Zahid, O.K. Abou-Zied,* R. Hashim, and T. Heidelberg

Characterization of the Head-Group and the Hydrophobic Regions of a Glycolipid Lyotropic

Hexagonal Phase Using Fluorescent Probes

Journal of Physical Chemistry C, 2011, 115, 19805–19810


21. N. Al-Lawatia, J. Husband, T. Steinbrecher, and O.K. Abou-Zied*

Tautomerism in 7-Hydroxyquinoline: A Combined Experimental and Theoretical Study in Water

Journal of Physical Chemistry A, 2011, 115,4195–4201


22. O.K. Abou-Zied* and N. Al-Lawatia

Exploring the Drug-Binding Site ″Sudlow I″ of Human Serum Albumin: The Role of Water and

Trp214 in Molecular Recognition and Ligand Binding

ChemPhysChem, 2011, 12, 270–274

Impact Factor: 3.42 (Wiley), Q1


Steady-State and Time-Resolved Spectroscopy of 2,2′-Bipyridine-3,3′-diol in Solvents and

Cyclodextrins: Polarity and Nanoconfinement Effects on Tautomerization



24. O.K. Abou-Zied* and N. Al-Lawatia

Specific Interaction of 7-Hydroxyquinoline with Trp-214 in the Drug-Binding Site IIA of Human

Serum Albumin

Proceedings of SPIE, The International Society for Optical Engineering, 2010, 7576, (18)1–11

2009 25. O.K. Abou-Zied* and O.I.K. Al-Shihi

Caging and Solvent Effects on the Tautomeric Equilibrium of 3-Pyridone/3-Hydroxypyridine in

the Ground State: A Study in Cyclodextrins and Binary Solvents



2008 26. O.K. Abou-Zied* and O.I.K. Al-Shihi

Characterization of Subdomain IIA Binding Site of Human Serum Albumin in its Native, Unfolded

and Refolded States Using Small Molecular Probes

Journal of the American Chemical Society, 2008, 130, 10793–10801


27. O.K. Abou-Zied* and O.I.K. Al-Shihi

Steady-State and Time-Resolved Fluorescence Investigation of 2-pyridone and 3-pyridone in

Solution and their Specific Binding to Human Serum Albumin

Proceedings of SPIE, The International Society for Optical Engineering, 2008, 6867, (K)1–12

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Investigating 2,2’-Bipyridine-3,3’-diol as a Microenvironment-Sensitive Probe: Its Binding to

Cyclodextrins and Human Serum Albumin



29. O.K. Abou-Zied* The Role of Water in Solvating the Hydrogen Bonding Center of 2-(2’-

hydroxyphenyl)benzoxazole

Chemical Physics, 2007, 337, 1–10


30. O.K. Abou-Zied* Steady-State Spectroscopy of New Biological Probes

Proceedings of SPIE, The International Society for Optical Engineering, 2007, 6449, (L)1–11

2006 31. O.K. Abou-Zied* and A.T. Al-Hinai

Caging Effects on the Ground and Excited States of 2,2′-bipyridine-3,3′-diol Embedded in

Cyclodextrins



32. O.K. Abou-Zied* Examining [2,2′-bipyridyl]-3,3′-diol as a Possible DNA Model Base Pair

Journal of Photochemistry and Photobiology A: Chemistry, 2006, 82, 192–201


2005 33. O. K. Abou-Zied*

A Spectroscopic Study of the Inclusion of Azulene by - and -cyclodextrins

Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, 2005, 62, 245–251


Before Joining Sultan Qaboos University

34. H. Wang, H. Zhang, O.K. Abou-Zied, C. Yu, F.E. Romesberg, and M. Glasbeek*

Femtosecond Fluorescence Upconversion Studies of Excited-State Proton Transfer Dynamics in 2-

(2’-hydroxyphenyl)benzoxazole (HBO) in Liquid Solution and DNA

Chemical Physics Letters, 2003, 367, 599–608


35. O.K. Abou-Zied, R. Jimenez, H.Z. Thompson, D.P. Millar, and F.E. Romesberg*

Solvent-Dependent Photoinduced Tautomerization of 2-(2’-hydroxyphenyl)benzoxazole

Journal of Physical Chemistry A, 2002, 106; 3665–3672


36. O.K. Abou-Zied, R. Jimenez, and F.E. Romesberg*

Tautomerization Dynamics of a Model Base Pair in DNA



37. A.K. Ogawa, O.K. Abou-Zied, V. Tsui, R. Jimenez, D. Case, and F.E. Romesberg*

A Photo-Tautomerizable Model DNA Base Pair

Journal of the American Chemical Society, 2000; 122; 9917–9920


11

38. E. W.-G. Diau, O.K. Abou-Zied, A.A. Scala, and A.H. Zewail*

Femtosecond Dynamics of Transition States and the Concept of Concertedness: Nitrogen Extrusion

of Azomethane Reactions



39. O.K. Abou-Zied and J.D. McDonald*

Picosecond Real Time Study of the Bimolecular Reaction O(3P) + C2H4 and the Unimolecular

Photodissociation of CH3CHO and H2CO

Journal of Chemical Physics, 1998, 109, 1293–1301

Impact Factor: 2.95 (American Institute of Physics), Q1

40. O.K. Abou-Zied, H.K. Sinha, and R.P. Steer*

Van der Waals Complexes of 2-Chloro-, 2-Methyl- and 1,3-Dimethylazulene with Rare Gases:

Microscopic Solvent Shifts, Structures and Binding Energies



41. O.K. Abou-Zied, D.R. Demmer, S.C. Wallace, and R.P. Steer*

Picosecond Dynamics of the S2 Excited States of Azulene and Its van der Waals Complexes with

Ar and Xe




S2-S0 Spectroscopy of Azulene and Its 2-Chloro, 2-Methyl, and 1,3-Methyl Derivatives

Journal of Molecular Spectroscopy, 1997, 183, 42–56



S2-S0 Spectroscopy of van der Waals Complexes of Azulene with Rare Gases

Journal of Physical Chemistry, 1996, 100, 4375–4381


44. O.K. Abou-Zied* A Study of the Electronic Spectroscopy and Vibrational Dynamics of Jet-Cooled Azulene, Its

Derivatives and van der Waals Clusters

Dissertation for Doctoral Degree, University of Saskatchewan, 321 pp. From: Diss. Abstr. Int., B

1995, 57(6), 3749

45. H.K. Sinha, O.K. Abou-Zied, M. Ludwiczak, A. Maciejewski, and R.P. Steer*

Origins of the Difference in Solvation by Alkanes and Perfluoroalkanes: Evidence from the S2-S0

Spectra of Jet-Cooled van der Waals Complexes of Xanthione and Azulene



46. H.K. Sinha, O.K. Abou-Zied, and R.P. Steer*

Ground and Excited State Dipole Moments of Pyranthione and Xanthione by the Electro-Optic

Method


Impact Factor: 1.90, # Citations: 13 (Elsevier); Ranking: Q3

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Participation in Conferences and Scientific Meetings

(presenter is underlined)

Since joining Sultan Qaboos University

1. O.K. Abou-Zied, S.A.J. Sulaiman, and H.U. Kulathunga

Interaction of fluorescein with human serum albumin: A model of a fluorescent tracer in

medicine, Photonics West, San Francisco, USA, February 2015

2. N.I. Zahid, O.K. Abou-Zied, and R. Hashim

Fluorescence probing of the temperature-induced phase transitions in water-driven self-

assembly of lipids, Photonics West, San Francisco, USA, February 2015

3. R. Hashim, O.K. Abou-Zied, and B.A. Timimi

Amphitropic liquid crystal phases from polyhydroxy sugar surfactants: Fundamental and

application studies, Photonics West, San Francisco, USA, February 2015

4. O.K. Abou-Zied Characterization of the warfarin drug-binding site of human serum albumin using fluorescent

probes, 1st International Caparica Conference on Chromogenic and Emissive Materials,

Costa de Caparica, Portugal, September 2014 (Invited Talk)

5. O.K. Abou-Zied Origin of the intense fluorescence of 2-aminopurine in aqueous solution, 13th Conference on

Methods and Applications of Fluorescence, Genoa, Italy, September 2013

6. O.K. Abou-Zied and N. Al-Lawatia

Estimating the ionization strength of the drug binding site “Sudlow I” of human serum albumin,

American Chemical Society, 243rd Meeting, San Diego, USA, March 2012

7. N. Al-Lawatia, T. Steinbrecher, and O.K. Abou-Zied

Interaction of 7-hydroxyquinoline with human serum albumin: Revealing the mode of molecular

recognition, Photonics West, San Francisco, USA, January 2012

8. J. Husband, N. Al-Lawatia, T. Steinbrecher, and O.K. Abou-Zied

7-Hydroxyquinoline: Characterization of a binding-site probe, Gordon Research Conference

(Photochemistry), Easton, USA, July 2011

9. N.I.M. Zahid, R. Hashim, T. Heidelberg, and O.K. Abou-Zied

Fluorescence spectroscopy of a glycolipid self-assembly using pyrene and tryptophan ester as

probes, International Conference on Materials for Advanced Technologies, Suntec, Singapore,

June 2011

10. O.K. Abou-Zied, N. Al-Lawatia, and J. Husband

Tautomerization in 7-hydroxyquinoline: A combined experimental and theoretical study in

different solvents, American Chemical Society, 241st Meeting, Anaheim, USA, March 2011

11. O.K. Abou-Zied and N. Al-Lawatia

Characterization of the drug binding site (subdomain IIA) of human serum albumin using 7-

hydroxyquinoline as a molecular probe, Photonics West, San Francisco, USA, January 2010

12. O.K. Abou-Zied Investigating the nature of subdomain IIA binding site of human serum albumin using resonance

energy transfer measurements

Gordon Research Conference (Molecular Energy Transfer), Ventura, USA, January 2009

13. O.K. Abou-Zied and O.I.K. Al-Shihi

Spectroscopy of pyridone/hydroxypyridine tautomerization mechanisms in N-heterocyclic systems

and their applications as potential biological probes, Photonics West, San Jose, USA, January 2008

13

14. O.K. Abou-Zied Steady-state spectroscopy of new biological probes, Photonics West, San Jose, USA, January 2007

15. O.K. Abou-Zied Effect of water solvation on the hydrogen bonding centers of a Watson-Crick base pair model:

Spectroscopic and molecular dynamics simulations studies, American Chemical Society, 40th

Western Regional Meeting, Anaheim, USA, January 2006

16. O.K. Abou-Zied Spectroscopic studies of tautomerization mechanisms in Watson-Crick A-T base pair models

American Chemical Society, 229th Meeting, San Diego, USA, March 2005

Before joining Sultan Qaboos University

17. O.K. Abou-Zied, R. Jimenez and F.E. Romesberg

Probing the tautomerization environment of base-pairs in DNA, American Chemical Society, 221st

Meeting, San Diego, USA, April 2001

18. R. Jimenez, O.K. Abou-Zied and F.E. Romesberg

Spectral probes of antigen-antibody dynamics, American Chemical Society, 221st Meeting, San

Diego, USA, April 2001

19. O.K. Abou-Zied, R. Jimenez, A.K. Ogawa and F.E. Romesberg

Femtosecond dynamics in model base pairs: The role of tautomerization, American Chemical

Society, 219th Meeting, San Francisco, USA, March 2000

20. R. Jimenez, O.K. Abou-Zied and F.E. Romesberg

Novel probes of antigen-antibody interactions and the progress of adaptive immunity, American

Chemical Society, 219th Meeting, San Francisco, USA, March 2000

21. O.K. Abou-Zied 37th SAS Pacific Conference on Chemistry and Spectroscopy, Ontario, USA, October 1999

22. O.K. Abou-Zied, H.K. Sinha, and R.P. Steer

4th International Conference in Solar Energy Storage and Applied Photochemistry, Cairo, Egypt,

January 1997


43rd Annual Western Spectroscopy Association Conference, Pacific Grove, USA, February 1996


3rd International Conference in Solar Energy Storage and Applied Photochemistry, Cairo, Egypt,

January 1995


XVIIth International Conference in Photochemistry, London, UK, July 1995


78th Canadian Society for Chemistry, Guelph, Canada, May 1995


Center of Excellence in Molecular and Interfacial Dynamics, Vancouver, Canada, May 1994


XVIth International Conference in Photochemistry, Vancouver, Canada, August 1993

29. O.K. Abou-Zied 75th Canadian Society for Chemistry, Edmonton, Canada, May 1992

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Research Grants

1. Principal-Investigator

Funding Agency: The research Council of Oman

Amount: 320,700 Omani Rials (equivalent to ~ 834,000 US dollars)

Duration: January 2014 – December 2016

Title: Towards a better understanding of protein-ligand interaction: The role of protein

flexibility in ligand recognition, biological function, and drug binding

2. Principal-Investigator

Funding Agency: Sultan Qaboos University



Title: Protein flexibility: Its role in ligand recognition and biological function

3. Co-Investigator Funding Agency: High Impact Research (HIR) Grant, University of Malaya, Malaysia

Amount: 8,665,500 Malaysian Ringgits (equivalent to ~ 2,662,622 US dollars)


Title: Fundamental science of self-assembly: Synthesis, characterization, formulation, and

implementation

4. External Principal-Investigator Funding Agency: Ministry of Science, Technology and Innovation (MOSTI), Malaysia

Program: Research and Development Collaboration Program

Amount: 170,000 Malaysian Ringgits (equivalent to ~ 55,000 US dollars)


Title: Ultrafast dynamics of water in lyotropic liquid crystal phases of branched chain

glycolipids

5. Co-Principal-Investigator Funding Agency: Sultan Qaboos University



Title: Synthesis and use of model base pair analogues for tautomerization studies in DNA

and its role in biological mutagenesis

6. Principal and Sole Investigator

Funding Agency: Sultan Qaboos University



Title: Investigating the role of proton transfer process in changing the genetic code and

causing mutations in biological systems

7. Co-Investigator

Funding Agency: University of California Energy Institute

Amount: 25,000 US dollars

Duration: March 1996 – February 1997

Title: Polymeric squaraine dyes for solar photovoltaics

15

International Collaboration University of Malaya, Malaysia

Karlsruhe Institute of Technology, Germany

Glycoteam GmbH, University of Hamburg, Germany

Washington University, St. Louis, Missouri, U.S.A.

Reviewer for:

Journal of Physical Chemistry Langmuir

Physical Chemistry Chemical Physics Chemical Communications

Molecular BioSystems ChemPhysChem

European Biophysics Journal Journal of Molecular Structure

Chemical Physics Letters Journal of Luminescence

Journal of Fluorescence Journal of Spectroscopy

Journal of Photochemistry and Photobiology A Spectrochimica Acta Part A

Journal of Photochemistry and Photobiology B ISRN Physical Chemistry

Journal of Pharmaceutical and Biomedical Analysis

Editorial Board Member of the Editorial Board for the ISRN Physical Chemistry Journal

Documents

Department of Chemistry, College of Science, Sultan Qaboos … · 2015-10-21 · Name: Osama Kamal Abou-Zied Date of Birth: February 1967 Nationalities: American, Egyptian Marital