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© Fraunhofer
DAS FRAUNHOFER IKTS ALS INNOVATIVER PARTNER IM BEREICH BIO- UNDMEDIZINTECHNIKAndreas Lehmann, Dr. rer. nat. Jörg Opitz
Medizintechnik in Sachsen
07.12.2016
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Our Business Divisions
MATERIALS ANDPROCESSES
MECHANICAL AND AUTOMOTIVE ENGINEERING
ELECTRONICS ANDMICROSYSTEMS
ENERGYMATERIALS ANDPROCESS ANALYSIS
OPTICS
BIO- AND MEDICALTECHNOLOGY
ENVIRONMENTAL ANDPROCESSENGINEERING
SYSTEMS EXPERTISE
TECHNOLOGY
EXPERTISE
WERKSTOFF-KOMPETENZ
MATERIALS DIAGNOSTICS
ReliabilityQuality assurance
Fraunhofer IKTS in profile
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Business DivisionBio- and Medical Technology
Competencies
� Development, processing and integration ofbiomaterials
� Shaping and surface technologies
� Microsystems technology
� Sensors and actuators
� Integration of functional mechatronic components
� (Bio)medical analytics and diagnostics
Dental technology
Implants/endoprosthetics
Instruments
Medical components
Biosensors and actuators
Analytics and diagnostics
Fraunhofer IKTS - BioMed
Applications
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CompetenciesBiomaterials
Development of customized biomaterials with defined property and structural parameters
Material groups
� Oxide ceramics as a high purity dense or porous bioceramics based on Al2O3 and ZrO2 (ATZ, ZTA, Y-TZP, Ca3(PO4)2) and HAP
� ceramic (lithium)
� Foam ceramic and metal foams
� Oxide and non-oxide ceramics with specific electrical, thermal and mechanical features
� Polymer ceramics and composites
� Individual material development
� DIN EN ISO 9001:2008 und EN ISO 13485
� Scale-Up to the pre-industrial scale
BioMed - competencies
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CompetenciesSensor and actuator
Development of functional materials, miniaturized components and systems
� Ceramic micro system technology (HTCC, LTCC)
� Thick film (screen, template, pad printing)
� Thin film technology (CVD, PECVD, ALD)
� Direct writing method (aerosol, inkjet)
� Biocompatible assembly and packaging technology
� Housing und Interfaces
� Functional components (di-, piezo and ferroelectrics)
� Linking structural and functional ceramics
� Application centres fortechnology testing
BioMed - competencies
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CompetenciesCharacterization
Monitoring & testing and diagnostic methods
� Complex material characterization on nano, micro and macro levels (TEM, SEM, AFM, AFAM)
� Biophysical characterization body and surfaces
� Development of in vivo and in vitro analysis systems and diagnostic systems
� Cell Tissue Monitoring
� Investigation of stimulation and suppression processes
� Fluorescence-based tumor diagnosis
� Quality assurance of production processes (inline und post mortem)� Fraunhofer IKTS branch
materials diagnostics
� Service and methoddevelopment
BioMed - competencies
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ApplicationsImplants
Material development
� Biofunctional and biomimetic ceramics
� Oxid ceramic based on Al2O3 and ZrO2
� High purity dense or porous Al2O3 bioceramics with sub-µm/nano-structures for shaped implants
� Foam ceramics and metal foams for bone replacement material
Technology development
� Foaming- and molding technologies, slip casting, sol-gel and plasma coating, generative techniques
� Bioceramic surface and shape body design
Knee endoprosthesis
BioMed - applications
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ApplicationsDental ceramics
Customer-specific material development
� Oxid ceramic based on Al2O3, ZrO2 and their dispersions with finely dispersed microstructure and high strength
� ceramic materials based on Li2Si2O5
Efficient process development
� Slip casting of ceramic components with complex geometries
� Closed CAD / CAM process chain certified EN ISO 13485:2003 + AC:2009
� 3D digitizer
Dental ceramics under UV illumination
SEM image Y-TZP
BioMed - applications
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ApplicationsBiosensors and -actorsSensors for diagnostics
� Multisensor-Arrays
� Cell Tissue Monitoring
� Development of nanoparticles for diagnostics
Bioactors
� Functional stimulation module (electric / acoustic / mechano-stimulation in vitro and in vivo)
� Ultrasonic transducer arrays for particle manipulation
Energy systems
� Scalable power transmission systems ex-vivo to in vivo (eg. for theranostical hip implants)
Mobile power transmissionsystem
Ultrasonic transducer arrays for particle manipulation
BioMed - applications
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ApplicationsMonitoring systems / testing and diagnostic systems
Process development
� Qualification optical diagnostics for medical and life sciences (OCT, Nanoraman)
� Monitoring of cell and bacterial growth processes
� Sensors for the detection of biogenic and biosynthetic polymers
� Intraocular pressure measurement using air-ultrasound
� Sterility detection by nanoparticles (SteriHealth®)
Device development
� Fluorescence-based cancer diagnostic (OCD) 3D visualization of a tooth using optical coherence tomography
BioMed - applications
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ApplicationsSurgical instruments and components
Materials, technology and component developments
� (Micro) Surgical instruments and cutting materials
� Ceramic tips for minimally invasive surgery
� Functional (conductive, bioactive, biosuppressive) layers
� Functional films
� Ceramic springs
� Components for X-ray equipment
Plasma gel-coated surgicalinstrument
BioMed - applications
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THANK YOU FOR YOUR ATTENTION!
Contact: Andreas Lehmann
Fraunhofer IKTSMaria-Reiche-Str. 201109 Dresden+49 351 [email protected]