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Dane County Oral Fluid Pilot Project-
Establishing an Oral Fluid Drug Testing
Program in Alabama
Curt Harper, Ph.D., F-ABFT
Alabama Department of Forensic Sciences
Candace Lightner, Founder and President
We Save Lives
Ted Savage, Forensic Toxicologist
Wisconsin State Laboratory of Hygiene, Forensic Toxicology Section
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
Dane County Oral Fluid Project
Ted SavageWisconsin State Laboratory of Hygiene
Madison, Wi
Overview
• Project design• Screen comparison• Extent of drugged driving• Other areas to investigate• DRE case studies
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
Project Design
• Collect 100 paired OF and blood specimen• Match and deidentify paired specimen
• Determine utility of OF detection device• Complete full drug testing on samples with
BAC>0.100 g/100mL• Extent of drugged driving esp. at high BACs
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
Positive Drug Screening Results:Oral Fluid vs. Blood
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5
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THC COC OP BZ MAMP AMP
OralFluid
Blood
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
OF Compared to BloodAnalyte Sensitivity Specificity
Positive Predictive Value
Negative Predictive Value Accuracy
THC 88% 87% 83% 91% 88%
Cocaine 100% 99% 86% 100% 99%
Amphetamine 100% 88% 14% 100% 88%
Methamphetamine N/A 99% 0% 100% 99%
Opiates 83% 99% 83% 99% 98%
Benzodiazepines 45% 99% 83% 94% 93%
All Drug Categories 82% 96% 70% 98% 94%
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
Phase I Results 104 valid oral fluid collections 24 arrests between 10:00 am-6:00 pm 57 of subjects + OF result in at least 1 category 17 subjects + OF in 2 or more categories Consistent correlation between OF and Blood
results 94% accuracy through all drug categories
76 of 104 subjects with alcohol 73 with BAC greater than 0.080 g/100mL
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
Total Blood Positive Vs. BAC
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
0
10
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ND 0.010-0.079 0.080-0.100 0.101-0.150 0.151-0.200 0.201-0.250 >0.251
No Drugs Present in Blood
Drugs Present in Blood
Phase II Results 116 specimens selected with BAC > 0.100g/100mL 17 (15%) subjects between 10:00am-6:00pm 83 (72%) subjects between 10:00pm-6:00am
81 (70%) subjects positive for 1 or more drug category 60 subjects (52%) positive for THC 10 subjects (9%) positive for cocaine
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
What Else?
• On the roadside testing• Compare correlation with potential time lapse
• Compare with quantified results• More DRE paired data• Push for partnerships from the start
• Help segue the future use and case law
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
DRE Case #1
• Driver with right of way stopped not turning• Eventually pulled into and parked in a lot
• Strong odor of THC• Indicated smoking within an hour prior
• Eyelid tremors and leg tremors• Slightly fast internal clock• Not knowing doesn’t make it legal!
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
DRE Case #2
• Two vehicle crash• Admission of heroin use
• Paraphernalia in vehicle
• Initial observations –slow and unsteady• Progressively more and more sleepy until
unable to coherently answer questions
• Narcotic Analgesic called• Morphine, Codeine, Methadone, BE, Clonaz,
Diaz, Nordiaz, Oxaz
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
DRE Case #3
• Responding to crash as a second crash occurred on scene
• Subject moving things in vehicle• Admits to having THC on person• 2 Lines of cocaine 2 days prior
• Stim and Dep• OF +THC & +Coc
• Only THC in Blood
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
DRE Case #4
• Single vehicle lodged up against house after knocking over utility pole • Heading southbound away from stated
destination
• Confused and repetitive questions• How do I estimate the passage of 30 seconds?• Walked backwards WAT
• “A lot more than THC at party, but I didn’t”• MDMA and Alprazolam detected
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
DRE Case #5
• Individual called in for reckless driving• DRE requested at hospital• Observations of subject
• Packets of synthetic marijuana in car
• DRE calls cannabis• ND by evidentiary and OF• Send-out detected 3 synthetic cannabinoids• Officer’s experience and observations!
WISCONSIN STATE LABORATORY OF HYGIENE - UNIVERSITY OF WISCONSIN
[email protected] Information
WISCONSIN STATE LABORATORY OF HYGIENE - TOXICOLOGY SECTION
Wisconsin State Laboratory of HygieneUW-Madison, School of Medicine and Public Health
2601 Agriculture DriveMadison, WI 53707
608.224.6241
Thank you!!
