Daily Essentials (Pack #2) • Multi-Probiotic • Omega-3 EPA • Omega-3 DHA • Co-Q10 • Multivitamin

DESCRIPTION Daily Essential Pack (# 2) of Functionalab, offers a complete supplement solution combining a multivitamin, a multi-strain probiotic, Omega-3 fatty acids and Co-Q10 to support optimal general health and vitality. This comprehensive pack includes Key ingredients combined together for optimal results;

• Multi-Probiotic helps support healthy digestive functions

• Omega-3 EPA helps support healthy cardiovascular functions

• Omega-3 DHA helps support healthy brain functions

• Co-Q10 impedes the formation of free radicals, and helps support optimal cardiovascular and immune health

CONTENT Functionalab’s line of Advanced Nutraceuticals offers potent nutrient blends of vitamins, minerals and other natural extracts to achieve optimal health. Our health scientists have selected only the purest and highest quality natural ingredients to maximize effectiveness. Our Personalized Packs propose complete supplement solutions in daily packets that combine the perfect assortment of vitamins, nutrients and natural extracts tailored to individual profiles or objectives. Daily Essential pack main objective is to

complement healthy food intake and regular exercise. This program also addresses general health and appearance. The bioactive combination of ingredients for optimal general health, cardiovascular health, as well as digestive health includes:

• 2 Ultra Health multivitamin with over 50 nutritional ingredients to support optimal health and vitality

• 2 Omega-3 softgels for optimal cardiovascular health

• 1 Co-Q10 tablet, an antioxidant that helps support cardiovascular and immune health

• 1 Multi-probiotic capsule that helps support healthy intestinal flora by delivering a clinically meaningful dose of beneficial microorganisms

FUNCTIONS Studies show that a high percentage of adults eat less than the minimum daily recommendation of 10 or more essential nutrients. Adequate amounts and proper balance of these nutrients are needed not only for maintaining good health, but also for the dietary management of the body’s structure as well as the optimal functioning of the body, such as the immune and gastrointestinal systems. Ultra Health has been carefully developed to contain the right proportions of vitamins, minerals, trace elements, and other nutrients without danger of toxic build-up or other side effects. The omega-3 softgels included in this pack offer essential fatty acids that help support cardiovascular health. It is specially coated to prevent fishy taste. Made from ultra-pure fish oil, it includes EPA (eicopentaenoic acid) and DHA

(docosahexanoic acid). The omega-3 fatty acid EPA is the direct precursor for the anti-inflammatory prostaglandins E1 and E3, whereas DHA is of primary importance for the structural integrity of neuronal membranes. DHA is essential for brain and visual development and is vital throughout pregnancy to support fetal brain growth and formation of the retina and visual cortex. Studies have shown that DHA, along with EPA may play an important role in cardiovascular health.

CoQ10 is a well known antioxidant that helps support the immune system and promote cardiovascular health by impeding the formation of free radicals. Coenzyme Q10 is a naturally-occurring antioxidant nutrient which retards free radical formation in biological systems. Coenzyme Q10 resembles vitamin E and vitamin K in chemical structure. Biochemically, it functions much like vitamin E in that it participates in certain antioxidant and free radical reactions. According to some experts, coenzyme Q10 should be considered an essential nutrient, as it is well established that coenzyme Q10 is essential for the health of every cell in the human body. Numerous studies indicate coenzyme Q10 also plays an important role in the maintenance of the entire cardiovascular system. Supplementation with coenzyme Q10 in patients has shown to be useful for the maintenance of already healthy blood pressure. Coenzyme Q10 is also important for the maintenance of blood vessels and heart muscle function.

Multiprobiotics formula helps support healthy intestinal flora by delivering a clinically meaningful dose of beneficial microorganisms. Oral supplements of live, beneficial intestinal micro-organisms for nutritional health and well-being are known as probiotics. When potent probiotic supplements, such as Multi-Probiotic, are supplied regularly, chances are greatly increased for establishing and maintaining a healthy population of beneficial intestinal microorganisms. Once established, a normal intestinal microflora rich in lactobacilli creates acidic conditions that are unfavorable for the settlement of pathogenic microorganisms. The special formulation of this comprehensive pack, Daily Essentials (#2), is providing a complete daily supplement solution to support optimal cardiovascular, immune, digestive, as well as general health.

SUGGESTED USE Take 1 pack per day with meals for a period of 3 months for optimal results. Do not exceed the recommended dose.

SIDE EFFECTS No adverse effects have been reported.

STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.

REFERENCES Cebra JJ. Influences of microbiota on intestinal immune system development. Am J Clin Nutr 1999;69:1046S-1051S. Collins MD, Gibson GR. Probiotics, prebiotics, and synbiotics: approaches for modulating the microbial ecology of the gut. Am J Clin Nutr 1999;69:1052S-1057S. Donnet-Hughes A, Rochat F, Serrant P, Aeschlimann JM, Schiffrin EJ. Modulation of nonspecific mechanisms of defense by lactic acid bacteria: effective dose. J Dairy Sci 1999;82:863-9. Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections [see comments]. Jama 1996;275:870-6. Gibson GR. Dietary modulation of the human gut microflora using prebiotics. Br J Nutr 1998;80:S209-12. Goldin BR. Health benefits of probiotics. Br J Nutr 1998;80:S203-7. Jacobsen CN, Rosenfeldt Nielsen V, Hayford AE, Moller PL, Michaelsen KF, Paerregaard A, Sandstrom B, Tvede M, Jakobsen M. Screening of probiotic activities of forty-seven strains of lactobacillus spp. by In vitro techniques and evaluation of the colonization ability of five selected strains in humans [In Process Citation]. Appl Environ Microbiol 1999;65:4949-56. Kirjavainen PV, Ouwehand AC, Isolauri E, Salminen SJ. The ability of probiotic bacteria to bind to human intestinal mucus. FEMS Microbiol Lett 1998;167:185-9. Pessi T, Sutas Y, Saxelin M, Kallioinen H, Isolauri E. Antiproliferative effects of homogenates derived from five strains of candidate probiotic bacteria [In Process Citation]. Appl Environ Microbiol 1999;65:4725-8. Tejada-Simon MV, Lee JH, Ustunol Z, Pestka JJ. Ingestion of yogurt containing Lactobacillus acidophilus and Bifidobacterium to potentiate immunoglobulin A responses to cholera toxin in mice. J Dairy Sci 1999;82:649-60. Venturi A, Gionchetti P, Rizzello F, Johansson R, Zucconi E, Brigidi P, Matteuzzi D, Campieri M. Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis. Aliment Pharmacol Ther 1999;13:1103-8. Wang X, Ma G, Zheng B, Tian H. [Effects of SL-probiotic preparation on the body weight and phagocytosis of white mice]. Wei Sheng Wu Hsueh Pao 1995;35:455-9. Giovannucci E, Stampfer MJ, Colditz GA, et al. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study [see comments]. Ann Intern Med 1998;129:517-24. Hughes DA. Effects of dietary antioxidants on the immune function of middle-aged adults. Proc Nutr Soc 1999;58:79-84. Johnson K, Kligman EW. Preventive nutrition: an 'optimal' diet for older adults. Geriatrics 1992;47:56-60. Kelly GS. Nutritional and botanical interventions to assist with the adaptation to stress. Altern Med Rev 1999;4:249-65. Miranda MS, Cintra RG, Barros SB, et al. Antioxidant activity of the microalga Spirulina maxima. Braz J Med Biol Res 1998;31:1075-9. Mukhtar H, Ahmad N. Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr 2000;71:1698S-1702S. Prior RL, Cao G. Antioxidant capacity and polyphenolic components of teas: implications for altering in vivo

antioxidant status. Proc Soc Exp Biol Med 1999;220:255-61. Shobana S, Naidu KA. Antioxidant activity of selected Indian spices . Prostaglandins Leukot Essent Fatty Acids 2000;62:107-10. van Poppel G, Verhoeven DT, Verhagen H, et al. Brassica vegetables and cancer prevention. Epidemiology and mechanisms. Adv Exp Med Biol 1999;472:159-68. Weisburger JH. Approaches for chronic disease prevention based on current understanding of underlying mechanisms. Am J Clin Nutr 2000;71:1710S-1714S. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 1999 Aug 7;354(9177):447-55. Markides M, Neumann MA, Byard RW, Simmer K, Gibson RA. Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants. Am J Clin Nutr 1994;60:189-194. Makrides M, Neumann MA, Gibson RA. Effect of maternal docosahexaenoic acid (DHA) supplementation on breast milk composition. Europ J Clin Nutr 1996;50:352-357. Martinez MJ. Tissue levels of polyunsaturated fatty acids during early human development. J Pediatr 1992; 120:S129-138. Morrow-Tlucak M, et al. Breastfeeding and cognitive development in the first 2 yes of life. Soc Sci Med 1988;26:635-639. Neuringer M, Anderson GJ, Conner WE. The essentiality of n-3 fatty acids for the development and function of the retina and brain. Ann Rev Nutr. 1988;8:517-541. Fux M, Levine J, Aviv A, et al. Inositol treatment of obsessive-compulsive disorder. Am J Psychiatry. 1996;153:1219–1221. Gelber D, Levine J, Belmaker RH. Effect of inositol on bulimia nervosa and binge eating. Int J Eat Disord 2001 Apr;29(3):345-8 Levine J. Controlled trials of inositol in psychiatry. Eur Neuropsychopharmacol. 1997;7:147–155. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001 Jun;21(3):335-9 Folkers K. Relevance of the biosynthesis of coenzyme Q10 and of the four bases of DNA as a rationale for the molecular causes of cancer and a therapy. Biochem Biophys Res Commun 1996;224:358-61. Folkers K, Osterborg A, Nylander M, Morita M, Mellstedt H. Activities of vitamin Q10 in animal models and a serious deficiency in patients with cancer. Biochem Biophys Res Commun 1997;234:296-9. Folkers K, Simonsen R. Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. Biochim Biophys Acta 1995;1271:281-6. Hofman-Bang C, Rehnqvist N, Swedberg K, Wiklund I, Astrom H. Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. The Q10 Study Group. J Card Fail 1995;1:101-7. Hofman-Bang C, Rehnquist N, Swedberg K, et al. Coenzyme Q10 as an adjunctive treatment of congestive heart failure. J Am Coll Cardiol. 1992;19:216A. Koroshetz WJ, Jenkins BG, Rosen BR, Beal MF. Energy

metabolism defects in Huntington's disease and effects of coenzyme Q10. Ann Neurol 1997;41:160-5. Langsjoen PH, Langsjoen A, Willis R, Folkers K. Treatment of hypertrophic cardiomyopathy with coenzyme Q10. Mol Aspects Med 1997;18:S145-51. Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors. 2005;25(1-4):147-52 Langsjoen H, Langsjoen P, Langsjoen P, et al. Usefulness of coenzyme Q10 in clinical cardiology: a long-term study. Mol

Aspects Med. 1994;15(suppl):S165–S175 Mortensen SA, Leth A, Agner E, Rohde M. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med 1997;18 Suppl:S137-44. Sander S, Coleman CI, Patel AA, Kluger J, White CM. The impact of coenzyme Q10 on systolic function in patients with chronic heart failure. J Card Fail. 2006 Aug;12(6):464-72.

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