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119th NC-ACS Sectional Conference Saturday, April 30, 2005
North Carolina State University Dabney and Cox Halls
On the Cover Our cover picture is taken from the brochure “Resources for Research in Chemistry” in the Research Triangle that was written during the spring of 1957 by William F. Little, then an assistant professor of chemistry at University of North Carolina at Chapel Hill. The information was extracted from a master inventory of research resources and capabilities at the Triangle universities prepared by a committee chaired by Marcus E. Hobbs, then professor of chemistry and dean of the graduate school at Duke University. The brochure was prepared as a recruiting tool for chemical companies throughout the U.S., along with a broader brochure on the Triangle region and the Triangle universities, generally. The objective was to capture the attention of companies planning new research laboratories and looking for potential sites. Brochures were also carried on visits by "faculty traveling salesmen" to companies who were willing to receive a representative from the Triangle effort. The Research Triangle Park was not yet assembled, but the success of faculty member visits to these companies, assessed by follow-up return visits of company representatives to the Triangle area, was in effect a feasibility test that led to the assemblage now known as Research Triangle Park (RTP). RTP was financed and developed entirely by private contributions to the Research Triangle Foundation for the common good of the state of North Carolina. The objectives were to diversify the industrial base of North Carolina, to raise the per capita income with technology-based industries, and to reverse a brain drain by providing a new profile of employment opportunities for the state's youth. On the three corners of the brochure are pictures of the current namesakes for the three major university’s chemistry departments. On the upper left is Francis P. Venable. This picture was taken in 1880 when beards where in fashion from the President on down. Venable’s father encouraged him to let his beard grow in order to look more mature. Charles W. Dabney appears on the lower left. Dabney was seriously considered for the chair of chemistry at UNC-Chapel Hill, but had made a commitment to a school in Kentucky. When Dabney was released from his commitment in Kentucky, Venable had already accepted the chair of chemistry position. Dabney then became the head of the Agricultural Experimental Station and was instrumental in the founding of North Carolina State University. On the middle right is Paul M. Gross, who was one of the organizers of the National Science Foundation and was its first Vice Chairman. He was also president of the AAAS and one of the original board members of RTP, as well as Chairman of the Department '29~'59, Dean of the Graduate School and Vice President of Duke University. The development and growth of RTP has been chronicled in the documentary "North Carolina's Research Triangle Park: An Investment in the Future", produced by PBS and aired by WUNC-TV:
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NORTH CAROLINA SECTION AMERICAN CHEMICAL SOCIETY
Fellow Chemists: Welcome to the 119th Sectional Conference of the NC Section of the American Chemical Society. This year's program was developed by our Chair-Elect 2005, Dr. Charles Goss of GlaxoSmithKline. The technical program features 69 interesting oral and poster presentations and will take place from 8:30 am – 11:40 pm. The General Session will be held immediately after the technical program. The General Session will begin with the 2005 NC-ACS Distinguished Speaker Lecture presented by Dr. Dan Comins, Professor of Chemistry, North Carolina State University. Eric Bigham, ACS Director District IV, will give a short update on issues facing the ACS. Students who have won the Undergraduate Scholarship and Barbara Whittaker Awards, as well as 50-year ACS members, will be recognized. The 2004 Chair’s award will be given to Meredith Storms and Bill Gutknecht. Finally, the Marcus E. Hobbs Service Award will be presented to Howie James of Waters Corporation. Lunch in the Marye Anne Fox Building will follow immediately after the general session. Following lunch, a workshop on Chemical Demonstrations will be held from 2:00 to 3:30 p.m. The goal of the workshop is to present and share demonstrations that relate to volunteering at the NC State Fair, schools or other venues. Many thanks to Dr. Bill Switzer and colleagues at North Carolina State University for organizing this event. The NC-ACS Local Section gratefully acknowledges Dr. Laura Sremaniak, Dr. Bill Switzer, Dr. Susan Hendrickson and other members of the North Carolina State University Chemistry Department for hosting the 2005 Local Section Conference. Dr. Charles Goss is gratefully acknowledged for developing the technical program and making arrangements for this conference. Finally, thanks to all of you for participating in the conference, and sharing your scientific results and thoughts. I might add that this has been a busy year for our section with the State Fair, National Chemistry Week, the NBC Health Fair and our hosting the SERM Meeting. This year promises to be just as busy…….and you can be part of it. Answer the call and volunteer when asked via e-mail and the Tarhelium. Best regards, Sol Levine 2005 Chair NC Section ACS
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Table of Contents
About the Cover ...................................................................................................... 2
Welcome Letter ....................................................................................................... 3
Table of Contents .................................................................................................... 4
Technical Program ............................................................................................. 5-10
2005 NC-ACS Distinguished Speaker ............................................................ 11-12
50-year ACS Members.......................................................................................... 13
Over 50-year ACS Members ........................................................................... 14-17
NC-ACS Awards and Scholarships Programs .............................................. 18-23
2005 NC-ACS Marcus E. Hobbs Award ....................................................... 24-25
NC-ACS Project SEED......................................................................................... 26
NC-ACS Discussion Groups Triangle Area Mass Spectrometry Discussion Group............................. 27 Triangle Chromatography Discussion Group.......................................... 28 19th Triangle Chromatography Symp. & Instr. Exhibit.......................... 29 Triangle Magnetic Resonance Discussion Group ................................... 30 Polymer Discussion Group...................................................................... 31 Younger Chemists Committee................................................................. 32
NC-ACS Local Section Information 2005 NC-ACS Local Section Officers ............................................... 33-35 Past Chairs of the NC-ACS Local Section ......................................... 36-37 NC-ACS Listserver.................................................................................. 38 NC-ACS Sponsors ................................................................................... 39 Facts about the NC-ACS Section ............................................................ 40
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GENERAL SESSION DABNEY HALL Room 124
11:50 am – 1:10 pm 1:15 pm: Buffet Lunch*
Sol Levine, NC-ACS Chair, Presiding
119th North Carolina-ACS Sectional Conference
Saturday, April 30, 2005 Dabney and Cox Halls
North Carolina State University
TECHNICAL PROGRAM General Session NC Distinguished Lecture, Awards,... 11:50 am– 1:10 pm Lunch ................................................. 1:15 pm Oral Presentations
Analytical Chemistry .................. 8:40 am – 11:00 am
Biological Chemistry & Chemical Education .......... 9:20 am – 11:00 am
Inorganic Chemistry & Physical Chemistry ........... 9:00 am – 11:00 pm
Nuclear Magnetic Resonance ..... 8:40 am – 11:20 am
Polymer Chemistry .................... 9:00 am – 11:00 pm Poster Presentations Display Time...................................... 8:30 am – 11:40 pm Presenter Discussion Times ............... 10:00 am – 10:20 am ...................................................... 11:00 am – 11:40 am
Analytical Chemistry Organic Chemistry Biological Chemistry & Chemical Education Inorganic Chemistry Materials Chemistry Nuclear Magnetic Resonance Physical Chemistry Polymer Chemistry
ACKNOWLEDGEMENTS The NC-ACS Local Section gratefully acknowledges the NCSU Chemistry Department for hosting this event, and Drs. Laura S. Sremaniak, Susan Hendrickson and William L. Switzer for coordinating the use of the facilities. Many thanks to the other assistants from NCSU.
• Presentation of the 2005 NC ACS Distinguished Lecture Award to:
Dr. Daniel L. Comins Department of Chemistry
North Carolina State University
Introduction by: Dr. George H. Wahl Department of Chemistry North Carolina State University
• Recognition of 50-year ACS members
• Update on Issues Facing the ACS from Eric Bigham (Director, District IV)
• Recognition of the 2004 Barbara Whittaker Awardees
• Recognition of the 2004 Undergraduate Scholarship Awardees
• Presentation of the 2004 Chair’s Award to Meredith Storms (UNC-Pembroke) and Bill Gutknecht (RTI International)
• Presentation of the Past-Chair Award
• Presentation of the 2005 Marcus E. Hobbs Award to Howie James and Sol Levine
* LUNCH will be served in the Marye Anne Fox Hall Lobby and Courtyard immediately after the General Session
Chemical Demonstration Workshop Marye Ann Fox Hall After lunch (~2:00 - 3:30 pm), Bill Switzer will lead a workshop on doing chemical demonstrations. Anyone considering volunteering at the NC State Fair (October 14-23, 2005), schools or other venues is encouraged to attend. Participants are also encouraged to bring their own demonstrations and ideas to share with the group. Participants should bring safety glasses if possible.
Questions about the program? Please contact: Dr. Charles A. Goss, Program Chair GlaxoSmithKline Five Moore Drive Research Triangle Park, NC 27709-3398 Phone: 919-483-9755 E-mail: [email protected]
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ANALYTICAL CHEMISTRY I Dabney Hall Room 331 8:40 am – 11:00 am Presider: W. Lin Coker III, Department of Chemistry, Campbell University
8:40 FTIR Time-Resolved Spectroscopic Study of Coordination Shell Effects in Iron Transport Systems. Jared J. Heymann, Richard A. Palmer, Alvin L. Crumbliss; Department of Chemistry, Duke University
9:00 Application of Fluorescence Imaging for the Investigation of Packed-Capillary LC Column Packing Density. Dawn M Stickle, James W. Jorgenson; Department of Chemistry, UNC-CH
9:20 Nanoparticle-based Delivery Vectors for Cellular Internalization and Targeting. Yanli Y. Liu, Stefan Franzen, Daniel L. Feldheim; Department of Chemistry, NCSU
9:40 Flow Counterbalanced Capillary Electrophoresis in Packed Capillaries. Wm. Hampton Henley, Richard T. Wilburn, Andrew M. Crouch, James W. Jorgenson; Department of Chemistry, UNC-CH
10:00 BREAK and POSTER DISCUSSION – refreshments in Dabney Hall Room 210
10:20 Micellar Selectivity Triangle for Classification of Chemical Selectivity in MEKC. Cexiong Fu, Morteza G. Khaledi; Department of Chemistry, NCSU
10:40 A Carbon Nanotube/Microfluidic Microsystem for Chemical Sensors. Qiang Fu, Jie Liu; Department of Chemistry, Duke University
ANALYTICAL CHEMISTRY II Dabney Hall Room 330 9:00 am – 11:00 am Presider: David J. Burinsky, Chemical Development Analytical Sciences, GlaxoSmithKline
9:00
Detection and Identification of Isoprene and Secondary Volatile Organics Using Selected Ion Chemical Ionization in a Quadrupole Ion Trap Mass Spectrometer. Karen S. Wendling, Desmond A. Kaplan, Gary L. Glish; Department of Chemistry, UNC-CH
9:20
Applications of Thermally Assisted-Collision Induced Dissociation in a Quadrupole Ion Trap. Alawee H. Racine, Gary L. Glish; Department of Chemistry, UNC-CH
9:40 Simple Software for Complex Instruments - Writing software to control analytical instrumentation. Desmond A. Kaplan, Philip M. Remes, Gary L. Glish; Department of Chemistry, UNC-CH
10:00 BREAK and POSTER DISCUSSION – refreshments in Dabney Hall Room 210
10:20 Characterizing the Thermodynamic Stability of Multi-domain Proteins Using SUPREX. Liangjie Tang, Michael C. Fitzgerald; Department of Chemistry, Duke University
10:40 Fast Collision Induced Dissociation in a 2D Linear Ion Trap and a 3D Quadrupole Ion Trap: More Product Ions in a Shorter Time. Connell Cunningham Jr. (1), Philip M. Remes (1) David J. Burinsky (2) Gary L. Glish (1); (1) Department of Chemistry, UNC-CH, (2) GlaxoSmithKline
ANALYTICAL CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-ANYL Prediction of Two-Dimensional MEKC-CE Separations. Sam Jenkins, Morteza Khaledi; Department of Chemistry, NCSU
2-ANYL Liposome Lysis Immunoassay Using Capillary Electrophoresis with Laser Induced Fluorescence Detection. Emnet Yitbarek, Morteza Khaledi; Department of Chemistry, NCSU
3-ANYL Chemistry of Small Silver Nanoparticles--What Is So Different? Matthew R. Branham, Royce W. Murray; Department of Chemistry, UNC-CH
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4-ANYL Product Ion Charge State Deconvolution Using Simultaneous Ion Molecule Reactions. David M. Black, Gary L Glish; Department of Chemistry, UNC-CH
5-ANYL Humulin® and beta-Cyclodextrin Complex. Daniel Shin (1), Josh Strickland (1), Matthew Lyndon (2), Antoine Al-Achi (1), Lewis Fetterman (1), Alan E. Tonelli (2); (1) Department of Pharmacy, Campbell University, (2) NCSU
6-ANYL Detection of DNA Sequence Variants by Non-Enzymatic Ligation. Mark A. Eckert, Lin He, Xinhui Lou; Department of Chemistry, NCSU
7-ANYL FTIR Analysis of Contaminants and Lichens Ablated from Statues with an Er:YAG Laser. Edward K Nakayama, Richard A. Palmer, Adele de Cruz; Department of Chemistry, Duke University
8-ANYL Theoretical Estimation of Peptide Internal Temperature During Collision Induced Dissociation in a Quadrupole Ion Trap. Philip M. Remes, Connell Cunningham Jr., Gary L. Glish; Department of Chemistry, UNC-CH
BIOLOGICAL CHEMISTRY and CHEMICAL EDUCATION Cox Hall Room 200 9:20 am – 11:00 am Presider: Pei Zhou, Department of Biochemistry, Duke University Medical Center
9:20 Investigation of the Enzyme/Substrate Interaction of Gamma-Glutamyl Carboxylase. Shannon L. Higgins-Gruber, Darrel W. Stafford, James W. Jorgenson; Department of Chemistry, UNC-CH
9:40 Probes for the Study of DNA Repair Mechanisms. Systematic Structural Variations in Interstrand Crosslinked DNA. Mateus Webba da Silva (1), Anne M Noronha (2), David M Noll (2), O. Michael Colvin (1), Paul S. Miller (2) and Michael P Gamcsik (1); (1) Department of Medicine, Duke University Medical Center, (2) Johns Hopkins University, School of Public Health, Baltimore, MD
10:00 BREAK and POSTER DISCUSSION – refreshments in Dabney Hall Room 210
10:20 Structure of a Novel mRNA Polymerase II Carboxy-Terminal-Domainbinding Protein intB. Ming Li, Hemali Phatnani, Arno Greenleaf, Pei Zhou; Department of Biochemistry, Duke University Medical Center
10:40 3D Symmetrical Double Helical DNA Models: Colorful Models for Visual Learners and Tactile Models for Blind and Visually Impaired Students. Susan Cady, Department of Chemistry, NCSU
BIOLOGICAL CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-BIO Conformation Coupled Enzyme Catalysis: Single Molecule and Transient Kinetics Investigation of Dihydrofolate Reductase. Ronald D. Smiley (1), Nina M. Antikainen (2), Stephen J. Benkovic (2), Gordon G. Hammes (1); (1) Department of Biochemistry, Duke University Medical Center, (2) Department of Chemistry, Pennsylvania State University
CHEMICAL EDUCATION POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-CE Rapid Method for the Microscale Extraction of Pigments from Frozen Spinach and Other Greens. Kristina L Toups, Laura E. Godwin, Maria T. Gallardo-Williams; Department of Chemistry, NCSU
2-CE Gold Nanoparticle Layering: From the Research Bench to the Teaching Lab. Ralph W Gerber, Maria Oliver-Hoyo; Department of Chemistry, NCSU
3-CE 3D Symmetrical Double Helical DNA Models: Colorful Models for Visual Learners and Tactile Models for Blind and Visually Impaired Students. Susan Cady; Department of Chemistry, NCSU
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INORGANIC CHEMISTRY AND PHYSICAL CHEMISTRY Dabney Hall Room 220 9:00 am – 11:00 am Presider: Richard A. Palmer, Department of Chemistry, Duke University
9:00
Reaction of TpRu(CO)(Ph)(NCMe) with electron rich olefins. Laurel A. Goj, Marty Lail, Kimberly C. Riley, T. Brent Gunnoe, Jeffrey L. Petersen; Department of Chemistry, NCSU
9:20
Magnetic and Spectroscopic Characterization of Electronically-Labile Cobalt bis(dioxolene) Complexes. Sofi Bin-Salamon (2), Scott H. Brewer (1), Daniel L. Feldheim (2), Stefan Franzen (2), Krishna Kumar (2), Simon Lappi (2), Kathryn E. Preuss (3), David A. Shultz (2); (1) Los Alamos National Laboratory, (2) Department of Chemistry, NCSU, (3) University of Guelph
9:40 The Study of H/D Exchange Reactions Catalyzed by Ruthenium(II). Yuee Feng (1), Marty Lail (1), David M. Conner (1), T. Brent Gunnoe (1), Jeffrey Petersen (2); (1) Department of Chemistry, NCSU, (2) West Virginia University
10:00 BREAK and POSTER DISCUSSION – refreshments in Dabney Hall Room 210
10:20 Temperature and loading rate dependence single molecule force spectroscopy of alpha-synuclein 12-mer. Chad J. Ray, Boris B. Akhremitchev; Department of Chemistry, Duke University
10:40 Dependence of Ligand Recombination as a Function of Temperature and Glycerol Content in Dehaloperoxidase. Jennifer L Belyea (1), Scott Brewer (1), Robin Casey (1), Robert Stanley (2), Martin Vos (3), Audrus Jasaitis (3), Stefan Franzen (1); (1) Department of Chemistry, NCSU, (2) Temple University, (3) Ecole Polytechnique
INORGANIC CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-INOR Synthesis and Characterization of Copper (I) Phenanthroline Compounds. Kevin P. McGowan, Richard A. Palmer; Department of Chemistry, Duke University
2-INOR Development of Copper-Based Catalysts for Carbonylation of Nitroarenes. Colleen Munro-Leighton, T. Brent Gunnoe; Department of Chemistry, NCSU
3-INOR RNA-Mediated Metal-Metal Bond Formation in the Synthesis of Hexagonal Palladium Nanoparticles. Lina A. Gugliotti, Daniel L. Feldheim, Bruce E. Eaton; Department of Chemistry, NCSU
4-INOR Mechanistic Investigations of the C-H Activation of Heteroaromatic Compounds Using a Ru(II) Complex. Karl A. Pittard (1), T. Brent Gunnoe (1), Jeffrey L. Petersen (2), Cynthia S. Day (3); (1) Department of Chemistry, NCSU, (2) West Virginia University, (3) Wake Forest University
5-INOR Study of Insertion Reactions Involving Unsaturated C-X Multiple Bonds (X = N or O) with a Ruthenium(II)-Phenyl Complex. John P. Lee, Karl A. Pittard, T. Brent Gunnoe; Department of Chemistry, NCSU
6-INOR Synthesis and Reactivity of Copper(I) Amido Complexes. Elizabeth D. Blue (1), T. Brent Gunnoe (1), Jeffrey Petersen (2); (1) Department of Chemistry, NCSU, (2) West Virginia University
7-INOR Determining the Mechanism of Crystal Growth of Templated Metal Halide Networks. Amanda A. Josey, Stephen J. Goettler, Jaap Folmer, James D. Martin; Department of Chemistry, NCSU
MATERIALS CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-MAT Bifunctional, Conjugated Oligomers for Orthogonal Self-Assembly. Jennifer A. Ayres, Diana Stefanescu, Christopher, B. Gorman; Department of Chemistry, NCSU
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NUCLEAR MAGNETIC RESONANCE I Cox Hall Room 214 8:40 am – 10:00 am Presider: Jeff MacDonald, Department of Biomedical Engineering, UNC-CH
8:40 Application of Projection-Reconstruction NMR to NOESY on a 29 kDa Protein. Brian E. Coggins (2), Ronald A. Venters (1), Pei Zhou (2); (1) Duke University NMR Center, (2) Duke University Department of Biochemistry
9:00 Zero Quantum and Zero Quantum-Less NMR of Lipid A (Endotoxin). Anthony A. Ribeiro; Duke NMR Center, Duke University
9:20 Metabolomic NMR Analysis of Mouse Urine for Cancer Diagnostics. Jeffrey M. Macdonald (1), Hannah Medford (1), Christopher Seagle (1), Oleg Favorov (1), David Threadgill (2); (1) Department of Biomedical Engineering, UNC-CH, (2) Department of Genetics, UNC-CH
9:40 Small Molecule Spies in Macromolecular Systems. Robert E. London; NIEHS
10:00 BREAK and POSTER DISCUSSION – refreshments in Dabney Hall Room 210
NUCLEAR MAGNETIC RESONANCE II Cox Hall Room 214 10:20 am – 11:20 am Presider: Roopa Thapar, Department of Biochemistry and Biophysics, UNC-CH
10:20 NMR solution structure of the E. coli DNA Polymerase III ? subunit. Geoffrey A. Mueller, Thomas W. Kirby, Eugene F. DeRose, Dawei Li, Roel M. Schaaper, Robert E. London; NIEHS
10:40 Pinning down a phosphate on SLBP and its implications for RNA recognition. Roopa Thapar (1), Christoph Borchers (1), Ram Samudrala (2), William F. Marzluff (1); (1) University of North Carolina at Chapel Hill, (2) University of Washington, Seattle
11:00 Expression, Purification, and Structural Studies of the RNase H Domain of the HIV-2 Reverse Transcriptase. W. Keither Merritt, Koteppa Pari, Thomas W. Kirby, Geoffrey A. Mueller, Eugene F. Derose, Robert E. London; NIEHS
NUCLEAR MAGNETIC RESONANCE POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-NMR Application of Projection Reconstruction Technique in NMR Side-chain Experiments and Ligand Titration of Proteins. Ling Jiang, Ling Jiang, Brian Coggins, Ming Li, Pei Zhou; Department of Biochemistry, Duke University Medical Center
ORGANIC CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-ORG Regioselective Suzuki coupling studies and the applications to the total synthesis of the lamellarins. Yanan Zhang, Scott T. Handy; State University of New York at Binghamton
2-ORG Studies on the Preparation of γ,δ-Unsaturated Ketones via Modified Carroll Rearrangements. Julianne M. Yost, Don M. Coltart; Department of Chemistry, Duke University
3-ORG C-Nitroso Compounds as Exogenous Nitric Oxide Donors. Harinath Chakrapani, David M. Gooden, Eric J. Toone; Department of Chemistry, Duke University
4-ORG Solid Supported [2+2+2]cycloaddition for Combinatorial Chemistry. Ramesh S. Senaiar, Douglas D. Young, Wendy Fields, Megha Sharma, Alexander Deiters; Department of Chemistry, NCSU
5-ORG Photoactivatable RNA Functions. Douglas D. Young, Alexander Deiters; Department of Chemistry, NCSU
6-ORG Synthesis of Modified Nucleotides for DNA Aptamer Selection. Dana A DiDonato, Bruce E. Eaton; Department of Chemistry, NCSU
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7-ORG Toward the Rational Synthesis of Isobacteriochlorins. Dilek Dogutan Kiper, Jonathan S. Lindsey; Department of Chemistry, NCSU
8-ORG The Total Synthesis of (+) – Hyperaspine. James J Sahn, Daniel L. Comins; Department of Chemistry, NCSU
9-ORG Synthesis of Novel Chiral 1,2-Diamines for Applications in Asymmetric Synthesis. Sonja S. Siefert, Daniel L. Comins; Department of Chemistry, NCSU
10-ORG Progress Towards the Total Synthesis of (-)-Lepadiformine. Lucas R. Marks, Daniel L. Comins; Department of Chemistry, NCSU
11-ORG Regioselective Halogenation of (S)-Nicotine and its Application Towards the Total Synthesis of (S)-Brevicolline. Florence C Fevrier, Daniel L. Comins; Department of Chemistry, NCSU
PHYSICAL CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-PHYS Elasticity Measurement of Amyloid Fibrils by Nanoindentation. Senli S. Guo, Boris Akhremitchev; Department of Chemistry, Duke University
POLYMER CHEMISTRY Cox Hall Room 204 9:00 am – 11:00 am Presider: Stephen L. Craig, Department of Chemistry, Duke University
9:00 Thermoplastic Polyacrylonitriles. Shawn R. Hutchinson, Alan E. Tonelli, Bhupender S. Gupta, Juan P. Hinestroza, William Oxenham; College of Textiles, NCSU
9:20 The Rheological Properties of Biopolymers in Synovial Fluid. Wendy E. Krause (1), Rebecca R. Klossner (1), Julie Wetsch (1, 2), Chelsea Davis (1); (1) TECS Department, College of Textiles, NCSU, (2) Currently at AATCC
9:40 Morphological and Mechanical Properties of Carbon Nanotube/Polymer Composites via Melt Compounding. Russell E. Gorga, William E. Dondero; TECS Department, College of Textiles, NCSU
10:00 BREAK and POSTER DISCUSSION – refreshments in Dabney Hall Room 210
10:20 DNA-Based Reversible Polymers in Solution and on Surfaces. Jun Xu, Stephen L. Craig; Department of Chemistry, Duke University
10:40 Layer-by-Layer Deposition of Polyelectrolyte Nanolayers on Natural Fibers. Kevin Hyde, Kevin Hyde, Mariana Rusa, Juan Hinestroza; College of Textiles, NCSU
POLYMER CHEMISTRY POSTER SESSION Dabney Hall 2nd Floor Posted: 8:30 am – 12:00 pm Discussion: 10:00 am – 10:20 am, 11:00 am – 11:40 am
1-POLY Synthesis and Properties of Novel Nylon-like Polymers Containing Methyl-α-Cyclodextrin. Brad J. Busche, C. Maurice Balik; Department of Materials Sciences & Engineering, NCSU
2-POLY Reorganization of Polymers with Small Molecule Hosts. Hyungchol Yang (1), David Jenkins (1), Cristian C. Rusa (2), Alan E. Tonelli (3); (1) College of Textiles, NCSU, (2) Family Health International, (3) NanoTex
3-POLY Reorganization of structure to alter the properties of PET. Jyotsna Vedula, Alan E. Tonelli; College of Textiles, NCSU
4-POLY Electrospun Nanofibers With Discrete Magnetic Domains. Juan Hinestroza (1), Carola Barrera (2), Carlos Rinaldi (2); (1) College of Textiles, NCSU, (2) University of Puerto Rico Mayaguez
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2005 NC-ACS Distinguished Speaker
Dr. Daniel L. Comins
Department of Chemistry North Carolina State University
“Asymmetric Synthesis and Synthetic Utility of Heterocyclic Building Blocks”
Abstract Over the years, heterocycles have been found to be versatile building blocks for the synthesis of functionalized organic compounds and structures of diverse architecture. In this area of organic synthesis, my research group has contributed by exploring the synthesis and synthetic utility of N-acylpyridinium salts I and N-acyldihydropyridones of the type II.
N
CO2R2
R1
O
I
5 electrophilicsubstitution
enolatealkylation
12
36
cycloadditions
4
1,4-addition
a
1,2-addition
N
OMe
CO2R*
TIPSSynthetic Intermediates
II
These heterocycles can be prepared enantiopure and have the potential to be used as precursors to indolizidines, quinolizidines, perhydroquinolines, various substituted piperidines, indole alkaloids, pipecolic acids, benzomorphans, peptide mimics, novel amino acids, scaffolds for combinatorial chemistry, and ligands for asymmetric synthesis. The importance of nitrogen heterocycles in natural products, biologically active compounds, and synthetic pharmaceuticals continues to drive research in the development of new strategies and methods for their synthesis and stereoselective substitution reactions. Our latest progress in this area will be presented.
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Biographical Sketch Professor Daniel Comins received his B.A. degree in Chemistry in 1972 from the State University of New York at Potsdam and his Ph.D. in 1977 from the University of New Hampshire. During 1977-1979, he was a Postdoctoral Associate under the direction of Professor A.I. Meyers at Colorado State University working on the total synthesis of the antitumor alkaloids N-methylmaysenine and maysine. He joined the faculty of Utah State University in 1979, became an Associate Professor in 1984, and moved to North Carolina State University as a Full Professor in 1989. In 1994, Professor Comins received the NCSU Alumni Association Outstanding Research Award and was an NCSU Inventors Award Recipient in the years 1993-96, 2000, and 2002-05. He is presently a consultant with Johnson and Johnson, Scynexis, ChiraChem International Company, BioCryst Pharmaceuticals, BioNumerik Pharmaceuticals, and the Research Triangle Institute. In 1995 and again in 1999, he was elected to the Advisory Board of the International Society of Heterocyclic Chemists. In 1995, he was selected as a member of the SUNY Alumni Honor Roll, and in 1997 he received the Minerva Award from SUNY-Potsdam. He has been a member of the Editorial Advisory Boards of Progress in Heterocyclic Chemistry and ARKIVOC. In October 1996, Professor Comins was appointed an Associate Editor of the Journal of Organic Chemistry. In 1998, he became a Japan Society Promotion of Science (JSPS) Research Fellow. A travel fellowship was awarded in 2002 to allow Dr. Comins to be a Medium Term Visitor at the University of Auckland, New Zealand. In addition to 9 book chapters and review articles, Professor Comins and coworkers have published over 140 papers and have been awarded over 25 patents in various areas of organic synthesis. The Comins group has accomplished the synthesis of over 40 alkaloids. Recent synthetic achievements include asymmetric syntheses of (+)-elaeokanine A, (+)-elaeokanine C, (-)-septicine, (-)-tylophorine, (-)-laudanosine, (+)-carnegine, (+)-glaucine, (-)-xylopinine, (-)-pumiliotoxin C, (-)-lasubine I, (+)-subcosine I, (-)-sedamine, (+)-camptothecin, (+)-10-hydroxycamptothecin, (-)-porantheridine, (-)-indolizidine 235B, (-)-indolizidine 205A, (+)-indolizidine 209D, (-)-indolizidine 207A, trans-decahydroquinoline alkaloid (+)-219A, piperidine alkaloid (+)-241D, (+)-dienomycin C, (+)-benzomorphan, (+)-metazocine, (-)-Nα-acetyl-Nβ-methylphlegmarine, (-)-perhydrohistrionicotoxin, (+)-luciduline, (+)-cannabisativine, (+)-streptazolin, (+)-desoxoprosopinine, (+)-deoxynojirimycin, (+)-allopumiliotoxin 267A, (-)-Nα-methyl-Nβ-acetylphlegmarine, (-)-phlegmarine, (-)-Nα-methylphlegmarine, (-)-Nβ-methyl-phlegmarine, (+)-lennoxamine, and (+)-hyperaspine. It is with great pleasure that the North Carolina Section of the American Chemical Society recognizes the accomplishments of Dr. Daniel L. Comins with the presentation of the 2005 North Carolina ACS Distinguished Lecturer Award.
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THE NC-ACS RECOGNIZES THESE INDIVIDUALS FOR 50-YEARS OF SERVICE
JOHN E. BARRY PINEHURST, NC ANDREW H. NICKOLAUS LAURINBURG, NC VLADIMIR PETROW CHAPEL HILL, NC JOHN EARL SIGSBY RALEIGH, NC VERNON E. SUMMERFELT CARY, NC
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THE NC-ACS RECOGNIZES THESE INDIVIDUALS FOR OVER 50-YEARS OF SERVICE*
* Members in bold have over 75 years of service
EDMUND H ALBRECHT, BS DURHAM, NC
HARRY C ALLEN, JR., PHD WEST END, NC
DON MARTIN ALSTADT, BS LORD CORPORATION, CARY,NC
EDWARD MCCOLLIN ARNETT, PHD DURHAM, NC
JOHN GELDART ASTON CHAPEL HILL, NC KENNETH ORION BEATTY JR., PHD RALEIGH, NC
LILIA BEAUCHAMP RALEIGH, NC
R O BEAUCHAMP RALEIGH, NC
THOMAS A BELL, MS RALEIGH, NC
ROY L BENNETT, PHD RALEIGHT, NC
ROBERT A BERNTSEN, PHD DURHAM, NC
EUGENE G BEZGELA, BS RALEIGH, NC
BARBARA BLAIR, PHD DURHAM, NC
ARTHUR C BOND, PHD CARY, NC
JAMES BENJAMIN BORDEN, PHD CHAPEL HILL, NC
HORACE DEAN BROWN, PHD DURHAM, NC
CARL E BRYAN, PHD RALEIGH, NC
RICHARD PIERSON BUCK, PHD DEPT. OF CHEM., UNC-CH
RALPH HARLAN BURROUGHS, JR PHD DURHAM, NC
BENJAMIN H CARPENTER, MS CARY, NC
CHESTER J CAVALLITO, PHD CHAPEL HILL, NC
DAVID W CHANEY, PHD RALEIGH, NC
RICHARD CHANG, PHD RALEIGH, NC
ARTHUR R CLARK, PHD PINEHURST, NC
HOWARD G CLARK, III PHD DURHAM, NC
S ROBERT COLLINS DURHAM, NC
WILLIAM COPULSKY, PHD RALEIGH, NC
WINFIELD PAUL COWGILL, MS RALEIGH, NC
ADRIAN H CUBBERLEY, BS DURHAM, NC
JOHN ANTHONY CUCULO, PHD RALEIGH, NC
CHICITA F CULBERSON, PHD DEPT. OF BIOLOGY, DUKE
JACK W DAUM, MS PINEHURST, NC
H MAUZEE DAVIS, PHD CHAPEL HILL, NC
CHARLES DICKSON, BS PINEHURST, NC
Page 14
HARRY M DONALDSON, BS RALEIGH, NC
JOHN A DURDEN, PHD RALEIGH, NC
WILLIAM F DURHAM, PHD RALEIGH, NC
ROBERT EBY, PHD CHAPEL HILL, NC
ERNEST L ELIEL, PHD DEPT. OF CHEM., UNC-CH
ALFRED H ELLISON, PHD RALEIGH, NC
GEORGE L EVANS, PHD CHAPEL HILL, NC
LEON FREEDMAN, PHD RALEIGH, NC
ROBERT ELLERY FULMER PHD CARY, NC
WILLARD MAX GENTRY, PHD DURHAM, NC
RICHARD D GILBERT, PHD APEX, NC
MURRELL K GLOVER, PHD CHAPEL HILL, NC
IRVING S GOLDSTEIN, PHD RALEIGH, NC
ARTHUR PAGE GOUGH, JR GARNER, NC
RONALD C. GREENE, PHD DURHAM, NC
PAUL S. GREER, MS CHAPEL HILL, NC WILLIAM F HAMNER, PHD RALEIGH, NC
MORTON HARFENIST, PHD CHAPEL HILL, NC
GEORGE C HARRISON, PHD APEX, NC
DONALD LEE HEYWOOD, PHD CHAPEL HILL, NC
RICHARD G. HISKEY, PHD CHAPEL HILL, NC
MARCUS EDWIN HOBBS, PHD DEPT. OF CHEM., DUKE
PATRICK HENRY HOBSON, PHD CHAPEL HILL, NC
GUNTHER C. HOLSING, PHD RALEIGH, NC
HENRY LIEN HSIEH, PHD FEARRINGTON
JOHN R HUIZENGA, PHD PINEHURST, NC
WILLIAM CECIL HUNT, PHD WEST END, NC
TONY M IMMEDIATA, PHD RALEIGH, NC
GRANNIS SAMUEL JOHNSON, PHD DURHAM, NC
PETER RAMSEY JOHNSTON, BS CARRBORO, NC
IVAN D JONES, PHD RALEIGH, NC
WILLIAM C KAY, PHD PINEHURST, NC
HENRY L. KING, CARY, NC
LAURANCE A KNECHT, PHD CHAPEL HILL, NC
JOSEPH KNOLL, PHD CARY, NC
SAMUEL E KRIKORIAN, PHD LITTLETON, NC
H GEORGE LATHAM JR., MS PITTSBORO, NC
MARGARET M LAYTON RALEIGH, NC
HARVEY D LEDBETTER, PHD PINEHURST, NC
SAMUEL G. LEVINE DEPT. OF CHEM., NCSU
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WALDO B LIGETT, PHD CHAPEL HILL, NC
WILLIAM F LITTLE, PHD CHAPEL HILL, NC
WILLIAM GILBERT LLOYD, PHD DURHAM, NC
RICHARD H LOEPPERT, PHD RALEIGH, NC
G. GILBERT LONG, PHD RALEIGH, NC
ROBERT J LOVIN, MS CARY, NC
T S MA, PHD CHAPEL HILL, NC
EUGENE E MAGAT, PHD DURHAM, NC
DAVID T MANNING, PHD CARY, NC
RALPH B MARCH CHAPEL HILL, NC
KENNETH SCOTT MCCARTY, PHD DURHAM, NC
EVA G. MCKENNA RESEARCH TRIANGLE PARK,NC
ARNOLD LAWRENCE McPETERS RALEIGH, NC
NARIMAN BOMANSHAW MEHTA, PHD CHAPEL HILL, NC
FRANK W MELPOLDER, BS DURHAM, NC
EDMUND MENDELL RALEIGH, NC
VIRGINIA C MENIKHEIM, PHD PITTSBORO, NC
STEPHEN JOSEPH METRO, PHD PINEHURST, NC
PAUL VIRGIL MEYER, BS PINEHURST, NC
JAMES W L MONKMAN, BS PINEHURST, NC
A E MONTAGNA, BS SOUTHERN PINES, NC
WILLIAM J MORAN, BS CARY, NC
EUGENE MORIARTY, BS PITTSBORO, NC
ELMER E MOST, PHD CHAPEL HILL, NC
HAROLD R MURDOCK JR, PHD CHAPEL HILL, NC
JAMES E MURPHY TARBORO, NC
LEWIS HAGOOD OWEN DURHAM, NC
ROBERT G PARR, PHD DEPT. OF CHEM., UNC-CH
CLAUDE PIANTADOSI, PHD CHAPEL HILL, NC
LEONARD PIERCE, JR., MS WEST END, NC
FREDERICK P PIKE, PHD RALEIGH, NC
DONALD M PREISS, PHD N MYRTLE BEACH, SC
MARJORIE S REMICK CHAPEL HILL, NC
FRANCES M RICHARDSON, MS RALEIGH, NC
EDWARD A. RICK, PHD RALEIGH, NC
EDGAR J ROBERTS, PHD BLADENBORO, NC
OLIVER A ROHOLT, JR., PHD RALEIGH, NC
JOHN N ROPER, JR., MS CHAPEL HILL, NC
JAMES K ROSSER, PHD FAYETTEVILLE, NC
BARBARA ROTH, PHD CHAPEL HILL, NC
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WALTER C SAEMAN, BS CHAPEL HILL, NC
AHMAD SAM, PHD KNIGHTDALE, NC
EDWARD GEORGE SAMSA, PHD CHAPEL HILL, NC
EDWARD SHERMAN, PHD DURHAM, NC
JOHN WARREN SLOAN, BS CARY, NC
ROMAN SLYSH, PHD RALEIGH, NC
PETER SMITH, PHD DURHAM, NC
F H SMITH, MS RALEIGH, NC PAUL S STENBUCK, BS CARY, NC
W N STOOPS, PHD CARY, NC HOWARD A STROBEL, PHD DEPT. OF CHEM., DUKE
PAUL N STROTHER, JR., CHAPEL HILL, NC
WILLIAM J TAPP, PHD APEX, NC
EDWARD A. TYCZKOWSKI DURHAM, NC
THOMAS E WALKER, PHD CUMBERLAND, NC
MATHIAS H J WEIDEN, PHD CHAPEL HILL, NC
RAYMOND CYRUS WHITE, PHD DEPT. OF CHEM., NCSU
EVERETT S WHITEHEAD SOUTHERN PINES, NC
PELHAM WILDER, JR., PHD DEPT. OF CHEM., DUKE UNIV
JOHN E WILSON, PHD DEPT. OF BIO-CHEM., UNC-CH
RICHARD ENOS WILSON, PHD FAYETTEVILLE, NC
WILLIAM E WILSON, JR., EPA, DURHAM, NC
WILLIS C WOOTEN JR., PHD CHAPEL HILL, NC
ROBERT W WORK, PHD RALEIGH, NC
GEORGE M WYMAN, PHD DURHAM, NC
LEO W ZIEMLAK, PHD RALEIGH, NC
CHARLES L ZIRKLE, PHD RALEIGH, NC
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Awards and Scholarship Programs
North Carolina ACS Distinguished Speaker The N.C. Distinguished Speaker Award gives the local section the opportunity to recognize an individual who has made a significant contribution to the NC-ACS Section, and who has made a distinguishable contribution to the chemical sciences.
2005 Daniel L. Comins, North Carolina State University 2004 Joseph M. DeSimone, University of North Carolina at Chapel Hill and North Carolina State
University 2003 Mansukh C. Wani, Research Triangle Institute 2002 Myung-Hwan Whangbo, North Carolina State University 2001 Aziz Sancar, University of North Carolina at Chapel Hill 2000 Radhakrishna M. Jayanty, Research Triangle Institute 1999 Louis D. Quinn, Duke University 1997 Monroe Wall, Research Triangle Institute 1996 Roger E. Miller, University of North Carolina at Chapel Hill 1994 James Jorgenson, University of North Carolina at Chapel Hill 1993 F. Ivy Carroll, Research Triangle Institute 1992 Maurice S. Brookhart, University of North Carolina at Chapel Hill 1991 Bertram O. Fraser-Reid, Duke University 1990 Richard V. Wolfenden, University of North Carolina at Chapel Hill 1989 Royce W. Murray, University of North Carolina at Chapel Hill 1988 Irwin Fridovich, Duke University 1987 Pedro Cuatrecasas, Burroughs Wellcome Company 1986 George H. Hitchings, Burroughs Wellcome Company 1986 Mary Ellen Jones, University of North Carolina at Chapel Hill Prior to 1986:
Ernest L. Eliel, University of North Carolina at Chapel Hill Edward M. Arnett, Duke University Ned A. Porter, Duke University Robert G. Parr, University of North Carolina at Chapel Hill Vivian T. Stannett, North Carolina State University Gertrude Elion, Burroughs Wellcome Company
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Marcus E. Hobbs Award The Marcus E. Hobbs award was established in 1988 to recognize members who have made significant, long-term contributions to the North Carolina Section of the American Chemical Society. The award was named for Marcus E. Hobbs, Department of Chemistry, Duke University, a model member who has worked closely with the North Carolina Section since he was Chair in 1945.
2005 Howie James – Waters Corporation Sol Levine – IBM and North Carolina State University, Retired 2004 Robert W. Morrison – North Carolina State University Brad Sturgeon – Western Caroplina State University 2003 Alvin L. Crumbliss – Duke University 2002 Thomas A. Lehman – Environmental Science & Technology 2001 Richard A. Palmer – Duke University 2000 Richard D. Gilbert – North Carolina State University 1999 John W. Hines – Research Triangle Institute 1997 Suzanne T. Purrington – Dept. of Chemistry, North Carolina State University 1996 Ernest L. Eliel – Dept. of Chemistry, UNC-Chapel Hill 1995 James L. Chao – IBM Corporation 1994 Joan T. Bursey – Radian Corporation 1993 William E. Hatfield – Dept. of Chemistry, UNC-Chapel Hill 1991 Eric C. Bigham – Burroughs Wellcome Company Peter Smith – Department of Chemistry, Duke University 1989 William L. Switzer – Dept. of Chemistry, North Carolina State University Halbert H. Carmichael – Dept. of Chemistry, North Carolina State University William F. Gutknecht, Research Triangle Institute 1988 Maurice M. Bursey – Dept. of Chemistry, UNC-Chapel Hill Robert G. Ghirardelli – Army Research Office Marcus E. Hobbs – Dept. of Chemistry, Duke University William F. Little – Dept. of Chemistry, UNC-Chapel Hill Monica R. Nees, Research Triangle Institute
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Undergraduate Research Scholarships 2004 NCACS Scholarship Committee Activity Report In 2004, the Scholarship Committee members were Bryce Chaney of BD Technologies, Dr. John Hines of RTI International, and Dr. James Chao of IBM. In 2004 we received 9 applications for the undergraduate scholarship. Two scholarship of $1,000 each were granted to the following students to assist them with their undergraduate research activities. Award certificates will be presented to these students at the 2005 NC-ACS Sectional Conference that will be held at NCSU on Saturday, April 30. 2005. Undergraduate Research Scholarship Awardees 2004 Kristina L. Toups, North Carolina State University; Maria Gallardo-Williams, Advisor John R. Williamson, North Carolina State University; Jonathan S. Lindsey, Advisor 2003 Laura Wingler, North Carolina State University; Bruce Eaton, Advisor
Patrick James Cleary, North Carolina State University; John Kadla, Advisor 2002 Andrew Garvin Taube, Duke University; Richard Palmer, Advisor
Anda Maria Cornea, Duke University; John York, Advisor 2001 Joyce E. Kung, Duke University; Eric J. Toone, Advisor Matthew Dedmon, UNC-Chapel Hill; Gary Pielak, Advisor Dave Chokshi, Duke University; Dhavalkumar Patel, Advisor 2000 Melanie Pribisko, UNC - Chapel Hill; Michael Gagne, Advisor 1999 Matthew Crowe, UNC - Chapel Hill; Gary L. Glish, Advisor
Lan-Anh Ngoc Nguyen, UNC - Chapel Hill; Roger E. Miller, Advisor Roger Alphonso Thornhill, III, UNC - Pembroke; Harold Teague, Advisor
1998 Michael Weaver, North Carolina State University; David Schultz, Advisor
Andrew Nyabwari, North Carolina Central University; Shawn Sendlinger, Advisor Porter Mason, Duke University; Weitao Yang, Advisor Julius Lucks, University of North Carolina, Chapel Hill; Tom Sorrell, Advisor
1997 Bogdon R. Cosofret, University of North Carolina, Chapel Hill
Brent Presley, Duke University Crystal Zerrad, Fayetteville State University
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Undergraduate Research Scholarship Awardees Continued 1996 Paul B. Glaser, Duke University
Ellen S. Gawalt, Duke University Frederick Wilson, Duke University Donna L. Phillips, North Carolina Central University Meredith Wilcox, Pembroke State University
1994 Preston T. Snee, University of North Carolina, Chapel Hill
Sunil Sudarshan, Duke University 1993 Lawrence P. Cogswell, III, Duke University
Edgar G. Estupinan, North Carolina State University Maria C. Garci, Duke University Dana B. Lacy, University of North Carolina, Chapel Hill Stephen Schneider, University of North Carolina, Chapel Hill
1992 Jason Altom, University of North Carolina, Chapel Hill
Mark Dransfield, University of North Carolina, Chapel Hill Melissa Hayworth, North Carolina State University Kim Kane-Maguire, Duke University Brian Scott, Pembroke State University Benjamin Trotter, University of North Carolina, Chapel Hill
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Barbara A. Whittaker Memorial Scholarship This award was created September 4, 1997 by the World-Wide Toxicology Department of Becton Dickinson in RTP to be given to an outstanding North Carolina State University senior majoring in chemistry who exemplified the personal qualities of dedication and scholarship which Barbara A. Whittaker possessed. It was endowed through contributions from Becton Dickenson, co-workers, and many friends and colleagues. The North Carolina Section of the American Chemical Society assisted in the establishment of this scholarship. Dr. Whittaker served many years as the editor of the ACS Section Newsletter, the TarHelium. A plaque presented by the American Chemical Society hangs in the lobby of Becton Dickinson in RTP and serves as a lasting tribute and reminder to her colleagues of the numerous contributions that she made as chemistry manager. It is fitting that this scholarship is one of the threads in the fabric woven between the local scientific academic community and scientific research industry in Research Triangle Park, NC. The scholarship is administered by the PAMS Foundation office at N.C. State University. Donations for this Memorial Scholarship may be sent to that office in care of the Barbara A. Whittaker Memorial Scholarship Endowment. Current Recipients 2004 Past Recipients: 2004 2003 2002 2001 Ed E. Cole 2000 Shawn Robert Campagna - Jonathan Lindsey, Advisor 1999 Larken Euliss
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2004 NC-ACS Chair’s Award
Meredith Storms from the Department of Chemistry at UNC-Pembroke receives a 2004 NC-ACS Chair’s Award for her leadership in continuation of the work with National Chemistry Week. William F. Gutknecht from RTI International receives a 2004 NC-ACS Chair’s Award for his excellent work compiling, editing, printing and distributing the program book for the 2004 Southeastern Regional Meeting of the ACS held in RTP.
Past Chair’s Award
Darrell S. Coleman receives this award for his distinguished service as the 2004 Chair of the North Carolina Section of the ACS.
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2005 Marcus E. Hobbs Award
Howie James
Waters Corporation
Howie James receives the 2005 Marcus E. Hobbs Award in recognition of his service to the North Carolina Section of the American Chemical Society. Howie has a B.A. degree in Chemistry from Syracuse University and an M.S. degree in Polymer Science from the University of Akron Polymer Institute. He has been a member of the American Chemical Society for 39 years and also a member of Sigma Xi. He was involved for several years on the ASTM D20.70.04 subcommittee on size exclusion chromatography and co-editor of the ASTM Bibliography on Liquid Exclusion Chromatography. Prior to joining Waters Corporation in 1977, he spent several years in polymer research with the General Tire & Rubber Co., Calgon Corporation, and Standard Oil of Ohio. He has held various field sales and marketing positions while at Waters and is currently an Executive Technical Sales Representative. He resides in Cary with his wife. Howie James has been an active participant in the Triangle Chromatography Discussion Group (TCDG) almost from the moment he arrived in the Triangle area in the mid-1980s, over 15 years ago. During that time he has been an active contributor in planning and executing TCDG activities such as workshops, seminars, and the annual Triangle Symposium and Instrument Exhibit. Most recently, Howie has served the TCDG as Acting President, replacing a lost officer in a time of group need, and then as the elected Program Chair (President-Elect), and President of the TCDG (1999). Howie has selflessly shared his experience, time, and energy with the TCDG throughout his involvement with the group. In addition to his direct contributions to the group, Howie has also found ways to contribute as a liaison with other discussion groups in the area (e.g., the South Carolina Laboratory Management Society, the Western Carolina Chromatography Discussion Group). His efforts with, and participation in, these groups translated into a sharing of information and ideas which would not have been otherwise available.
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2005 Marcus E. Hobbs Award
Sol Levine
IBM and NCSU, Retired
Sol Levine receives the 2005 Marcus E. Hobbs Award in recognition of his service to the North Carolina Section of the American Chemical Society. Sol is a long-time member of the American Chemical Society. After taking early retirement from IBM, Sol moved to the Triangle area in the 1990s. He has worked in teaching positions at North Carolina Central University, Durham Tech and North Carolina State University. Upon arriving in North Carolina, Sol immediately became involved with the Local Section by serving as Registration Chair for the 1998 Southeastern Regional meeting. He was the "guinea pig" registration chair for the first ever attempt at on-line registration at a regional meeting. This meant that he often had to enter the registration information himself because of the inevitable bugs in the software. After serving the 1998 Regional Meeting, he was elected Local Section Secretary for two consecutive terms and then stepped up to serve as General Chair of the 2004 Southeastern Regional Meeting. Most recently, he has allowed himself to be appointed Local Section Chair for 2005, after the Chair-Elect was forced to resign when he moved from the area. Sol also represents the NC Section at the regional level, having been elected to a 3-year term as treasurer of the Southeastern Regional Meeting Corporation. Sol has made and continues to make an admirable contribution to both Local Section and Regional ACS activities. Although it is a bit unusual to nominate a standing section Chair for the Marcus E. Hobbs service award, Sol Levine's history of involvement is unusual and outstanding.
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Project SEED
Summer Educational Experiences for the Disadvantaged Winner of the 2001 Presidential Awards for Excellence in Science, Mathematics, and Engineering Mentoring
Project SEED is designed to encourage economically disadvantaged high school students to pursue career opportunities in the chemical sciences. The program places economically disadvantaged high school students in academic, industrial and government research laboratories for 8-10 weeks during the summer to experience “hands-on” research. Each student completes a chemical research project under the supervision of a scientist mentor and receives an educational award. Since 1968, the Project SEED Program has made it possible for more than 4500 talented high school students to conduct research in local chemical laboratories across the country. National direction for Project SEED is provided by the ACS Committee on Project SEED. Our local Project SEED Director is Kenneth Cutler.
Project SEED is for students from an economically disadvantaged background with an annual family income below $32,000 or does not exceed 200% of the Federal Poverty Guidelines for family size. Exceptions can be made for incomes of up to $44,000, depending on family size and circumstances.
Students who have not graduated from high school are eligible for the Summer I program, and those returning for a second summer of research may participate in the Summer II program.
College scholarships (for a first-year nonrenewable) are available for SEED students who have graduated from high school and plan to attend college. The scholarships are restricted to students who will major in a chemical science field such as chemistry, chemical engineering, biochemistry, or materials science. The scholarships are intended to assist former SEED participants in their transition from high school to college.
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NC-ACS Discussion Groups
The Triangle Area Mass Spectrometry Discussion Group (TAMS) serves a diverse group of scientists, from both academia and industry. TAMS is based in the Research Triangle Park, conveniently located between Chapel Hill, Durham, and Raleigh. Attendance at the meetings is typically 35-45 scientists and students, with some meetings drawing in excess of 100 people. To meet the interests of such a variety of scientists with diverse interests, a balanced program between theory and applications is attempted, as well as covering a variety of applications. Due to the large number of scientists in the biotechnology and pharmaceutical industries, the application seminars are weighted towards these areas. More information, as well as a list of previous seminars and speakers is located at the following URL:
http://membership.acs.org/N/NCarolina/tamsdg/tams1.htm
To join the TAMS group, please send an e-mail to one of the officers below.
Co-Chairs Affiliation E-mail address Dr. Jon Williams GlaxoSmithKline [email protected] Dr. Michael Fitzgerald Duke University [email protected] Dr. Michael Goshe
North Carolina State University
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NC-ACS Discussion Groups
The purpose of the Triangle Chromatography Discussion Group is to maintain and promote an interest in and to provide an opportunity for discussion and exchange of information with respect to all fields of chromatography. The membership is open to anyone interested in the field of chromatography.
The TCDG sponsors a number of speakers throughout the year and an annual Triangle Symposium and Instrument Exhibit. The 22nd Triangle Symposium and Instrument Exhibit will be held at the McKimmon Center at North Carolina State University on Thursday, May 19th, 2005.
CURRENT OFFICERS
PRESIDENT Steve Klose Varian Inc.
PRESIDENT-ELECT Sherry Movassaghi Bayer Crop Science
PAST PRESIDENT Amir Malek
Wyeth Vaccine Research [email protected]
SECRETARY Joe Hudson
Bayer Crop Science joe.hudson@bayercropscien
ce.com
TREASURER James Blake
Research Triangle Institute [email protected]
For more information, visit: http://RTPnet.org/~tcdg
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The 22nd Triangle Chromatography Symposium and Instrument Exhibit
McKimmon Center
N.C. State University Thursday
May 19th, 2005
Register at: http://www.rtpnet.org/tcdg/registration.html
Registration fees for Symposium and Exhibit - all fees include lunch on May 19th Advanced Registration: $35 Regular, $10 for Students On-Site Registration: $55 Regular, $15 for Students
Exhibit-Only Registration is free
• Refreshments: Available in the Exhibit Hall (AM and PM) • Exhibitor Seminars: Seminar Rooms for exhibitor presentations on state-of-the-art topics • Continued Training: GLP/GMP Certificates of Attendance • Prize Drawing: Contributions by many of the Exhibitors - Grand Prize contributed by the TCDG • Posters: Local student competition; local university/industry research; vendor developments • TCDG Election: Opportunity to vote for TCDG Officers
Invited Speakers
Dr. David Hage University of Nebraska Lincoln, NE
Analysis of Proteins & Biomolecules by Ultra fast Affinity Chromatography
Dr. Ruth Winecker NC Office of the Chief Medical Examiner
Post-mortem Forensic Toxicology, Medicine Chemistry and The Law
Dr. Nicolle S. Tulve US EPA/ORD/NERL, Exposure Measurements
and Analysis Branch, RTP, NC Data Collected in the EPA's NERLHEM Program
to Evaluate Children's Aggregate Exposure to Pesticides in the Residential Environment
Dr. Gary Glish Department of Chemistry
University of North Carolina, Chapel Hill Characterizing Intact Proteins with
Quadruple Ion Trap Mass Spectrometer
Paul St. Jean Waters Corporation
Scientific Approach to Analytical Instrument Qualification
Dr. Philip Wyatt Wyatt Technology, Santa Barbara, CA Mysteries of Light Scattering Revealed
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NC-ACS Discussion Groups
It is the goal of the Triangle Magnetic Resonance Discussion Group to promote interactions and foster a stimulating and collaborative environment for the local NMR community. The Triangle NMR Discussion Group is an American Chemical Society Group of scientists interested in all areas of magnetic resonance, working in the North Carolina area. The group’s web page below is regularly updated with information on local events.
http://membership.acs.org/N/NCarolina/tmrdg/ The group also maintains an email list for updates on local seminars and symposia. To subscribe to this list go to http://listserv.unc.edu/, search for trimr and fill out the form. For further information contact any of the Officers listed below.
2004 - 2005 Executive Committee
Tom O'Connell, Chair GlaxoSmithKline R & D 5 Moore Drive P.O. Box 13398 Research Triangle Park, NC 27709 919-483-1535 Thomas.M.O'[email protected]
Hanna Gracz, TreasurerN.C. State University Dept. of Biochemistry P.O. Box 7622 Raleigh, NC 27695-7622 919-515-8907 [email protected]
Jim Beery, Secretary BASF Corporation Agricultural Products 26 Davis Drive Research Triangle Park, NC 27709-3528 919-547-2589 [email protected]
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NC-ACS Discussion Groups
POLYMER DISCUSSION GROUP
The Polymer Discussion Group was founded in 1967 to promote polymer chemistry and physics in all aspects, foster the educational and professional growth of its members, increase contacts between people engaged in polymer work in order to exchange knowledge and stimulate ideas, sponsor lectures, conferences, and other means to promote these objects and the general cause of polymer chemistry and physics. The Polymer Discussion Group meets on the second Thursday of each month at the N.C. State University Club for dinner and a seminar by a noted polymer scientist. The May meeting of each year is devoted to the Richard Gilbert Student Symposium, in which graduate students at local universities present their research and compete for cash awards. The symposium is sponsored by Lord Corporation.
2004-2005 OFFICERS
Chair Dr. Stephen Craig Duke University (919) 660-1538
Treasurer Dr. Juan Hinestroza NC State University
(919) 515-9426 [email protected]
Chair-Elect
Dr. Bruce Novak NC State University
(919) 515-2996 [email protected]
Secretary Dr. Russell E. Gorga NC State University
(919) 515-6553 [email protected]
For more information, visit: http://membership.acs.org/N/NCarolina/pdg/
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NC-ACS Discussion Groups
YOUNGER CHEMISTS COMMITTEE
The Younger Chemists Committee (NC-YCC) was founded in 1999 to encourage greater participation in the ACS in the Local Section by its younger members. Membership is targeted toward those chemists in the NC Section of the ACS who are under 35 years of age who show an interest in the group. There is no membership fee. The YCC’s primary goal is to make the ACS more accessible to the younger chemist. The YCC also has the responsibility to ensure that the special needs of the younger chemists are included in the goals and operations of the ACS. The YCC has events designed to provide informative lectures and discussions for career development and advancement. Events are not limited to scientific talks nor restricted to younger members. At all functions a social atmosphere is intended to bring younger chemists in the area to meet and network in a friendly environment. The YCC is also involved in events to bring chemistry to the community through projects such as National Chemistry Week and the NC State Fair.
YCC OFFICERS
President Darrell Coleman
Secretary Cindy Mitman PPD Discovery
Vice President Chris Lowden PPD Discovery
Treasurer Matt Clapham
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2005 NC-ACS Local Section Officers
Chair, 2005 Sol Levine PO Box 98996 Raleigh, NC 27624 (919) 676-3740 [email protected]
Chair-Elect, 2005 Charles A. Goss GlaxoSmithKline Five Moore Drive PO Box 13398 RTP, NC 27709 (919) 483-9755(W) [email protected]
Past-Chair, 2004 Darrell S. Coleman [email protected]
Secretary, 2005-2006 Jay M. Brown, Esq. Law Offices of Jay M. Brown 123 Barnes Spring Court Cary, NC 27519 (919) 303-0206 [email protected]
Editor, Tarhelium, 2003-present Keith Levine RTI International 3040 Cornwallis Road PO Box 12194 Research Triangle Park, NC 27709-2194 (919) 541-8886 (V) (919) 541-7208 (F) [email protected]
Treasurer, 2005-2006 Joan T. Bursey 101 Longwood Pl Chapel Hill, NC 27514-9584 [email protected]
Director, District IV Eric C. Bigham GlaxoSmithKline Five Moore Drive PO Box 13398 RTP NC 27709-3398 (919) 483-9844 (W) (919) 315-0430 (F) [email protected]
Councilor, 2005-2007 Robert W. Morrison, Jr. 5009 Larchmont Drive Raleigh, NC 27612 (919) 787-2397 [email protected]
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Councilor, 2005-2007 Laura S. Sremaniak Department of Chemistry-8204 North Carolina State University Raleigh NC 27695 (919) 515-2937 (W) [email protected]
Alt. Councilor, 2005-2007 Richard M. Forbis Department of Chemistry-Campus Box 3290 University of North Carolina at Chapel Hill Chapel Hill, NC 27599-3290 (919) 962-2096 (W) (919) 962-2388 (F) [email protected]
Councilor, 2003-2005 James L. Chao IBM Corporation PO Box 12195 Dept WUO/667 RTP, NC 27709 (919) 543-3054 (W) (919) 558-0066 (F) [email protected]
Alt. Councilor, 2005-2007 Alan E. Tonelli Textile Engineering, Chemistry and Science North Carolina State University Raleigh NC 27695 (919) 515-6588 (W) [email protected]
Councilor, 2004-2006 Alvin L. Crumbliss Chemistry-Box 90346 Duke University Durham NC 27708-0346 (919) 660-1540 (W) (919) 660-1605 (F) [email protected]
Alt. Councilor, 2004-2006 Nick Oberlies RTI International 3040 Cornwallis Road PO Box 12194 RTP, NC 27709-2194 (919) 541-6958 (W) [email protected]
Councilor, 2004-2006 Richard A. Palmer Chemistry-Box 90346 Duke University Durham NC 27708-0346 (919) 660-1539 (W) (919) 660-1605 (F) [email protected]
Alt. Councilor, 2004-2006 Christopher T. Lowden Synthematix 4815 Emperor Blvd. Suite 214 Durham, NC 27703 (919) 274-5842 (V) (919) 474-0762 (F) [email protected]
Ex-officio Maurice M. Bursey 101 Longwood Pl. Chapel Hill, NC 27514-9584 (919) 493-3025 (H) [email protected]
Alt. Councilor, 2003-2005 Shawn C. Sendlinger Department of Chemistry North Carolina Central University 1801 Fayetteville St. Durham, NC 27707 (919) 560-6297 (W) (919) 530-5135 (F) [email protected]
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Ex-officio Ernest L. Eliel Department of Chemistry-Campus Box 3290 University of North Carolina at Chapel Hill Chapel Hill, NC 27599-3290 (919) 962-6198 (W) (919) 962-2388 (F) [email protected]
Ex-officio Project SEED Coordinator Kenneth A. Cutler Department of BBRI North Carolina Central University 1801 Fayetteville St. Durham, NC 27707 (919) 530-6172 (V) (919) 530-7998 (F) [email protected]
Ex-officio TAMSDG Co-Chairs Dr. Jon D. Williams GlaxoSmithKline Five Moore Drive RTP, NC 27797-3398 919-483-5270 (W) [email protected] Dr. Michael Fitzgerald Dept. of Chemistry Duke University 919-660-1547 [email protected] Dr. Michael B. Goshe North Carolina State University Department of Molecular and Structural Biochemistry 139 Polk Hall Raleigh, NC 27695 919-513-7740 [email protected]
Ex-officio TCDG Chair Steve Klose Varian, Inc. [email protected] Ex-officio TMRDG Chair Thomas M. O'Connell GlaxoSmithKline (919) 483-1535 (W) [email protected] Ex-officio PDG Chair Stephen Craig Dept. of Chemistry - Box 90346 Duke University Durham, NC 27708-0346 (919) 660-1538 (W) (919) 660-1605 (F) [email protected] Ex-officio YCC Chair Darrell S. Coleman [email protected]
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ree, UNC, Chapel 2005 Sol LevIBM, N
2004 Darrell
2003 John A.
2002 Susan CParadigm
2001 Maury
2000 BradleyNIEHS
1999 George
1998 Russell NCSU
1997 Daniel LMagella
1996 ThomasUniversLaborat
1995 MichaeGlaxoW
1994 MichaeUNC Ch
1993 Robert BurrougCompan
1992 CharlesNCSU
1991 James L
1990 Donald
1989 Alvin LUnivers
1988 WilliamChapel H
1987 William
1986 Eric C. Wellcom
1985 Robert
1984 BernardResearc
1983 Louis DUnivers
1982 KathryMallinc
1960 S. Y. Ty1981 William F. Gutknecht, ine, retired from
Past Chairs of the NC-ACS Local Section**Founded February 22, 1896
Hill Research Triangle Institute CSU
1959 John W. Dawson, Office of Ordnance Research, Duke University
1980 Forrest W. Getzen, NCSU S. Coleman, Lilly
1979 Eric Wiechert, Cutter Laboratories
Myers, NCCU
. J. Sumner, Genetics 1958 Frederick R. Darkis,
Liggett & Myers Tobacco Company
1978 Richard A. Palmer, Duke University Balik, NCSU
1977 Suzanne T. Purrington, NCSU 1957 George O. Doak, United
States Public Health Service E. Sturgeon,
1976 Monica R. Nees, NC Science and Technology Research Center
1956 Frances C. Brown, Duke University
H. Wahl, NCSU
J. Linderman, 1955 Pelham Wilder, Duke
University 1975 Maurice M. Bursey, UNC Chapel Hill . Norwood,
n Laboratories 1954 Walter J. Peterson North Carolina State College 1974 Richard J. Thompson, EPA
A. Lehman, Duke ity/Magellan ories
1973 Halbert H. Carmichael, NCSU 1953 Arthur Roe, UNC Chapel
Hill 1972 Peter Smith, Duke
University 1952 Frank H. Smith, North Carolina State College
l T. Riebe, ellcome Inc.
1971 Vivian Stannett, NCSU 1951 John W. Nowell, Jr., Wake Forest College
l T. Crimmins, apel Hill 1970 Robert G. Ghirardelli,
Army Research Office-Durham
1950 Charles K. Bradsher, Duke University
W. Morrison, hs Wellcome y 1949 Samuel B. Knight, UNC,
Chapel Hill 1969 G. Gilbert Long, NCSU G. Moreland,
1948 Douglas G. Hill, Duke University
1968 Monroe E. Wall, Research
Triangle Institute . Chao, IBM
1947 Charles S. Black, Wake Forest College
M. Preiss, IBM
. Crumblis, Duke ity 1946 Oscar K. Rice, UNC,
Chapel Hill 1967 E. Clifford Toren, Duke
University E. Hatfield, UNC ill 1945 Marcus E. Hobbs, Duke
University 1966 J. Charles Morrow, UNC
Chapel Hill L. Switzer, NCSU 1965 J. Keith Lawson,
Chemstrand Research Center 1944 Willis A. Reid, NCSU Bigham, Burroughs e Company
1943 Sherman Smith, UNC, Chapel Hill
1964 Ralph C. Swann, NCSU Izydore, NCCU 1963 William F. Little, UNC
Chapel Hill Spielvogel Army h Office 1942 Charles S. Black, Wake
Forest College 1962 Howard A. Strobel, Duke University . Quin, Duke
ity 1941-42 Ivan D. Jones, North Carolina State College 1961 Richard H. Leoppert,
NCSU n MacLeod, krodt, Inc.
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1911 G. M. McNider, Ag. Experiment Station
1926 James T. Dobbins, UNC 1940-41 Walter Earl Jordan, North Carolina State College 1925 Frank E. Rice, North
Carolina State College 1910 William M. Allen, Ag. Experiment Station
1939-40 Edwin C. Markham, UNC, Chapel Hill 1924 Francis W. Sherwood,
North Carolina State College 1909 William A. Syne, Ag. and Mechanical College
1938-39 Nevill Isbell, Wake Forest Collge 1923 John O. Halverson, North
Carolina State College 1908 James E. Mills, UNC 1937-38 Warren C. Vosburgh, Duke University 1907 William H. Pegram, Trinity
College 1922 Alvin S. Wheeler, UNC
1936-37 Edward Mack, UNC Chapel Hill 1921 Paul M. Gross, Trinity
College 1906 Charles H. Herty, UNC 1935-36 Ralph W. Bost, UNC,
Chapel Hill 1905 C. B. Williams, N C Department of Ag.
1920 James M. Bell, UNC
1918-19 John W. Nowell, Wake Forest College 1934-35 John H. Saylor, Duke
University 1904 Alvin S. Wheeler, UNC
1902-03 Charles E. Brewer, Wake Forest College
1917 Howard B. Arbuckle, Davidson College 1933-34 Horace D. Crockford,
UNC Chapel Hill 1901 William A. Withers, Ag.
and Mechanical College 1916 James K. Plummer, Ag.
Experiment Station 1932-33 Francis W. Sherwood, North Carolina State College
1900 B. W. Kilgore, N C Experiment Station
1915 John W. Nowell, Wake Forest College 1930-32 Lucius A. Bigelow, Duke
University 1899 Charles Baskerville, UNC 1914 James M. Bell, UNC 1929 Frank K. Cameron, UNC 1896-98 Francis P. Venable, UNC 1913 Leon F. Williams, Ag. and
Mechanical College 1928 L. G. Willis, North Carolina State College
1912 Lucius B. Lockhart, Raleigh 1927 Paul M. Ginnings,
Greensboro College
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NC-ACS Listserver We encourage all people with an interest in the chemistry profession to subscribe to the NC-ACS Listserver, which is the email equivalent of bulk mailing. The list is moderated so that only approved messages are sent; the subscriber's email will not become overwhelmed with "junk" email. Approved postings include ACS meeting announcements and all job announcements. Contact Bill Switzer ([email protected]) to post a message. There is no charge to the subscriber and no charge to anyone listing either a job or a job opening. Jobs openings can be permanent or temporary, such as post-doctoral positions. ACS membership is not required. This is a public service of the NC Section of the ACS and N.C. State University. Subscription instructions are given on the local section web page, but they require sending one message address to: [email protected] The message field should say: subscribe ncacs <your name> The field <your name> is required. The subject line is ignored. The subscription address is your return address. If your address has changed, or you have recently transferred into the North Carolina section, please go to the national ACS web page at http://www.acs.org/ and click on the update address link under ACS Programs and Services. You cannot change your address of record through the local section.
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NC-ACS Sponsors
North Carolina Section American Chemical Society
The CIIT Centers for Health Research is a not-for-profit research institute,
conducting fundamental research that focuses on the action of chemicals on
biological systems
Founded in 1886, Sigma Xi is the international honor society of research
scientists and engineers, with a distinguished history of service to
science and society.
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Facts about the NC-ACS Local Section
Courtesy of Professor Maurice M. Bursey, The University of North Carolina, Chapel Hill
• The American Chemical Society was founded in 1876 in New York, then the center of chemical research in the country.
• Local Sections were not started outside of New York until 1890, when Rhode Island members formed a section. Earlier they had threatened to start a new chemical society because of the restriction of activities to New York.
• The North Carolina Section (1896) was the first in the South. About half a dozen local sections had been established in the North.
• Members of the North Carolina Section in 1896 were mostly professors at colleges and university and scientists at the North Carolina Experiment Station.
• Drive for a section in North Carolina came primarily from Charles Baskerville, a new professor at the University of North Carolina, Chapel Hill.
• The first president of the North Carolina Section was Francis Venable, head of the chemistry department at the University of North Carolina, Chapel Hill. He was president for three years, a record so far unmatched by any successor.
• The first meeting was in Raleigh, on February 22. Undoubtedly this date was chosen because it was a school holiday (George Washington's birthday). Travel to the meeting would have taken a long time. For example, from the University of North Carolina, Chapel Hill, attendees would have had to take the spur train to University Station, then the main railroad line through Durham to Raleigh!
• The program was quite extensive. Several members doing their own research gave research reports on their work.
• At first the North Carolina Section's area covered the whole state. Meetings were held all over the state accessible by train in spite of the substantial amount of travel involved. Often travel involved one or two night's stay at the meeting city.
• B. W. Kilgore of the Experiment Station was the first government/industrial chemist to be the section president.
• William Withers of the Agricultural and Mechanical College, now North Carolina State University, was another early president. He was famous for his research on the poisonous constituent of untreated cotton, gossypol.
• In time other Sections were split off from the North Carolina Section, as the number of chemists grew in North Carolina and demands on their time prevented far-ranging travel. Today there are five sections or parts of section of the American Chemical Society in North Carolina, covering all but a few of the most rural of the 100 counties.
• Fewer than 20 chemists were at the first meeting 100 years ago. Today there are over 3000 chemists in the five sections of North Carolina. Of these five, the North Carolina Section is still the largest. It extends from the Research Triangle north and south to the borders with Virginia and South Carolina, and has about 2600 members.
• Most of these 2600 members are employed in the Research Triangle Park, with its heavy research basis in pharmaceuticals, agricultural products, electronics, environmental research, and basic chemical and biochemical research. There are also large numbers of chemists at area colleges and universities in chemistry, biochemistry, chemical engineering, textile chemistry, environmental science, and materials science departments.