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CYP450 Inhibitors or Herbal CYP450 Inhibitors INDUCERS - CYTOCHROME P450 (CYP) ENZYMES DRUG TABLE Copyright Pharmacology Weekly Inc CYP1A2 CYP2B6 CYP2C8 CYP2C9 CYP2C19 CYP2D6 CYP2E1 CYP3A4 Genetic Polymorphis ms Genetic Polymorphism s Genetic Polymorphis ms Genetic Polymorphis ms Carbamaz epine Clotrima zole Phenobar bital Phenytoi n Primidon e Psoralen Smoking Barbitu ates Mepheny toin Phenoba rbital Phenyto in Primido ne Roflumi last Carbamaz epine Phenytoi n Rifabuti n Rifampin Aprepitan t Barbitura tes Carbamaze pine Primidone Rifampin Vigabatri n Barbitur ates Norethin drone Phenytoi n Rifampin Carbamaz epine Ethanol Phenobar bital Phenytoi n Primidon e Rifampin 4- methylpy razole Ethanol Isoniazi d Amprenavi r Barbituat es Carbamaze pine Clotrimaz ole Dexametha sone Efavirenz Ethosuxim ide Griseoful vin Modafinil Nevirapin e Oxcarbaze pine Phenobarb ital Phenytoin Prednison e Primidone Rifabutin

CYP450 Inhibitors Inducer

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Page 1: CYP450 Inhibitors Inducer

CYP450 Inhibitors or Herbal CYP450 Inhibitors

INDUCERS - CYTOCHROME P450 (CYP) ENZYMES DRUG TABLECopyright Pharmacology Weekly Inc

CYP1A2 CYP2B6 CYP2C8 CYP2C9 CYP2C19 CYP2D6 CYP2E1 CYP3A4

GeneticPolymorphisms

GeneticPolymorphisms

GeneticPolymorphisms

GeneticPolymorphisms

CarbamazepineClotrimazolePhenobarbitalPhenytoinPrimidonePsoralenSmoking

BarbituatesMephenytoinPhenobarbitalPhenytoinPrimidoneRoflumilast

CarbamazepinePhenytoinRifabutinRifampin

AprepitantBarbituratesCarbamazepinePrimidoneRifampinVigabatrin

BarbituratesNorethindronePhenytoinRifampin

Carbamazepine EthanolPhenobarbitalPhenytoinPrimidoneRifampin

4-methylpyrazoleEthanolIsoniazid

AmprenavirBarbituatesCarbamazepineClotrimazoleDexamethasoneEfavirenzEthosuximideGriseofulvinModafinilNevirapineOxcarbazepinePhenobarbitalPhenytoinPrednisonePrimidoneRifabutinRifampinRifapentineRitonavirTopiramate

HerbalsCYP1A2

HerbalsCYP2B6

HerbalsCYP2C8

HerbalsCYP2C9

HerbalsCYP2C19

HerbalsCYP2D6

HerbalsCYP2E1

HerbalsCYP3A4

GeneticPolymorphisms

GeneticPolymorphisms

Hypericum     perforatum

Eleutherococcus   senticoccusHypericum    perforatum

Eleutherococcus    senticoccusHypericum   perforatum

Page 2: CYP450 Inhibitors Inducer

Panax ginsengPanax    quinquefolius

Panax ginsengPanax    quinquefolius

Page 3: CYP450 Inhibitors Inducer

CYP450 Inducers (or) Herbal   CYP450 Inducers

INHIBITORS - CYTOCHROME P450 (CYP) ENZYMES DRUG TABLECopyright Pharmacology Weekly Inc

CYP1A2 CYP2B6 CYP2C8 CYP2C9 CYP2C19 CYP2D6 CYP2E1 CYP3A4

GeneticPolymorphisms

Genetic   Polymorphisms

GeneticPolymorphisms

GeneticPolymorphisms

AmiodaroneAtazanavirCimetidineCiprofloxacinCitalopramClarithromycinDiltiazemEnoxacinErythromycinEstradiolFluvoxamineInterferonIsoniazid KetoconazoleMethoxsalenMibefradilTegaserod

ThiopetaTiclodipine

AnastrozoleEzetimibe (p)GemfibrozilMontelukastNicardipineSulfinpyrazoneTrimethoprim

AmiodaroneAtazanavirCimetidineClopidogrelCotrimoxazoleDelavirdineDisulfiramEfavirenzFenofibrateFluconazoleFluorouracilFluoxetineFluvastatinFluvoxamineGemfibrozilImatinibIsoniazidItraconazoleKetoconazoleLeflunomideLovastatinMethoxsalenMetronidazoleMexiletineModafinilNalidixic acidNorethindroneNorfloxacinOmeprazoleContraceptivesParoxetinePhenylbutazoneProbenecidSertralineSulfamethoxazoleSulfaphenazoleSulfonamidesTacrineTeniposide

CimetidineCitalopramDelavirdineEfavirenzFelbamateFluconazoleFluoxetineFluvastatinFluvoxamineIndomethacinIsoniazidKetoconazoleLansoprazoleModafinilOmperazoleOxcarbazepineProbenecidTiclodipineTopiramate

AbirateroneAmiodaroneAsenapineBuproprionCelecoxibChloroquineChlorpheniramineChlorpromazineCimetidineCinacalcetCitalopramClemastineClomipramineCocaineDarifenacinDesipramineDiphenhydramineDoxepinDoxorubicinDuloxetineEscitalopramFebuxostatFluoxetineFluphenazineHalofantrineHaloperidolHydroxychloroquineHydroxyzineImatinibLevomepromazineMethadoneMetoclopramideMibefradilMidodrineMoclobemideNefazodone NorfluoxetineParoxetinePerphenazine

Disulfiram AmiodaroneAmprenavirAprepitantAtazanavirBoceprevir CimetidineCiprofloxacinClarithromycinCyclosporineDanazolDelavirdineDiltiazemEfavirenzErythromycinEthinyl EstradiolEzetimibe (p)FluconazoleFluoxetineFluvoxamineGestodeneImatinibIndinavirIsoniazidItraconazoleKetoconazoleMethylprednisoloneMibefradilMiconazoleMifepristoneNefazodoneNelfinavirNicardipineNifedipineNorethindroneNorfloxacinNorfluoxetineOxiconazolePosaconazolePrednisone

Page 4: CYP450 Inhibitors Inducer

TiclodipineTipranavirTroleandomycinVoriconazoleZafirlukastZileutin

PropafenonePropoxyphenePropranololQuinacrineQuinidineRanitidineRanolazineRitonavirSertralineTegaserodTerbinafineThioridazineTiclodipineTipranavirTripelennamine

QuinineRanolazineRitonavirRoxithromycinSaquinavirSertralineTelaprevirTelithromycinTroleandomycinVerapamilVoriconazoleZafirlukastZileutin

HerbalsCYP1A2

HerbalCYP2B6

HerbalsCYP2C8

HerbalsCYP2C9

HerbalsCYP2C19

HerbalsCYP2D6

HerbalsCYP2E1

HerbalsCYP3A4

GeneticPolymorphisms

GeneticPolymorphisms

Allium sativumBergamottinHarpagophytum   ProcumbensLycium barbarum

Allium sativumHarpagophytum   procumbens

Alpinia glangaAlstonia scholarisAndrographis    paniculataCatharanthus roseusCimicifuga racemosaCinnamomum   burmanniiEleutherococcus   senticoccusGycyrrhiza glabraHydrastis canadensisMelaleuca   leucadendronPanax ginsengPanax   quinquefoliusPiper nigrumPunica granatumRheum palmatumSantalum albumStrychnos ligustrinaSyzygium aromaticumTinospora crispaZingiber aromaticum

Piper Methysticum

Allium sativumAmmi visnagaAzadirachta indicaCimicifuga racemosaHarpagphytum   procumbensHydrastis canadensisNaringenin compoundsPanax ginsengPanax quinquefoliusStrychnos ligustrinaUncaria tomentosa

Note: (p) = parent drug


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