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CurriculumVitae
11/2016-Phd Student in Basic And Applied Biomedical Sciences
Laboratory of Biochemistry and Advanced Biology Department of Drug
Science University of Catania, Catania, Italy 01/2016Pharmacist
Professional
Qualification.10/2007-07/2015MasterDegreeinPharmacy.VOTE97/110UniversityofCatania,Catania,Italy09/2013–07/2015ExperimentalthesiscarriedoutattheDepartmentofDrugScience,Biochemistrysection.Titleofthethesis:RoleofHemeOxygenaseinbenignprostatichypertrophyRapporteur:Prof.LucaVanella.09/2001–07/2006Diplomaofcomputerexpertwithvote100/100ITIS"E.Torricelli",Sant'Agata(ME)Practical-theoreticalknowledgeofthefollowingtechniques:WesternBlot,IncellWestern,homogenizationandproteinquantificationoftissues,spectrophotometry,cellularviability(MTT),cellcultures,RT-PCR,ROSmeasurement,DNA-damage,assaysGSH,ELISA,OILREDmethod,cellsmigration,LOOHassay.Mainsubjects/professionalskillspossessed:anatomy,generalandanalyticalchemistry,organicchemistry,microbiology,Biology,molecularbiology,biochemistry,Generalphysiology,pharmacology,toxicology,technicalandpharmaceuticallegislation,pharmaceuticalchemistry.
MarcoRaffaeleDateofbirth:20/04/1987
Address:ctrdaSanFrancesco235,98063GioiosaMarea(ME)Nationality:ItalianMobile:+393272442419E-mail:[email protected]
PersonalSkillsandCompetencesLanguagesMotherlanguage:ItalianOtherslanguages:EnglishB1SpanishA2ComputerskillsandcompetencesWindows:ExcellentOthersOS:GoodOffice:ExcellentInternet:ExcellentSocialskillsandcompetencesGoodandprofessionalcommunicationskillsandpropensitytoteamwork.Motivationforlearning,reliabilityandseriousness,tolerancetostress.Drivinglicence:TypeA3andB
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Professionalexperience
06/2019Scholarshipaward“OutgoingVisitingStudent”05/2018–12/2018VisitingPhDstudentNewYorkMedicalCollege,15DanaRoad,Valhalla,NY10595,UnitedStatesofAmerica.05-2017ParticipationintheorganizationoftheInternationalWorkshop"NewFrontiersinBiochemistryandMolecularMedicine"atScuolaSuperiorediCataniaUniversityofCatania.09-2016PhDstudentin"BasicandAppliedBiomedicalSciences"attheDepartmentofDrugScience,biochemistrysection.UniversityofCatania09-2016ObtainingacertificateofparticipationintheInternationalWorkshop"9thInternationalConferenceonHemeOxygenasePrague2016",atPurkyneInstitute(Prague)03/2016-09/2016VolunteerResearchassistantattheDepartmentofDrugScience,biochemistrysection.UniversityofCatania.In-cellWestern,cellcultures,extractionandtransplantationofpancreaticislandsinrats,LOOHassay,ELISA,immunohistochemistry,cellularviability,ROSmeasurement,DNA-damage,annex,caspase,celltreatments,cellsmigration,RT-PCR,MiRNA.04/2015–05/2015ExperimentalthesiscarriedoutabroadNewYorkMedicalCollege,15DanaRoad,Valhalla,NY10595,UnitedStatesofAmerica.WesternBlot,cellcultures;Electrophoresis;Proteinhomogenizationandquantificationoftissues,spectrophotometry,celltreatmentsandinductionadipogenesis,RT-PCR,OILREDmethod.11/2012–04/2013InternshipinPharmacyPharmacyDr.RagusaVincenzo,ViaUmberto41,12,MilitelloinValdiCatania(CT).Assistancetothesaletothepublic,managementofthecashier,customerrelationship,ordersandwarehousemanagement.
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Pubblications
HemeOxygenase-1InhibitionSensitizesHumanProstateCancerCellstowardsGlucoseDeprivationandMetformin-MediatedCellDeath.RaffaeleM,PittalàV,ZingalesV,BarbagalloI,SalernoL,LiVoltiG,RomeoG,CarotaG,SorrentiV,VanellaL.IntJMolSci.2019May27;20(10).pii:E2593ProtectiveEffectsofCaffeicAcidPhenethylEster(CAPE)andNovelCapeAnalogueasInducersofHemeOxygenase-1inStreptozotocin-InducedType1DiabeticRats.SorrentiV,RaffaeleM,VanellaL,AcquavivaR,SalernoL,PittalàV,IntagliataS,DiGiacomoC.IntJMolSci.2019May17;20(10).pii:E2441.BeneficialEffectsofThymoquinoneonMetabolicFunctionandFattyLiverinaMurineModelofObesity.MariaLicari,MarcoRaffaele,ZacharyF.Rosman,JosephSchragenheim,LarsBellner,LucaVanella,RitaRezzani,LuigiRodella,FrancescaBonomini,EdithHochhauser,MichaelAradandNaderG.AbrahamJNutrFoodSci2019,9:1,DOI:10.4172/2155-9600.1000751Mesentericlymphnodesasalternativesiteforpancreaticislettransplantationinadiabeticratmodel.VerouxM,BottinoR,SantiniR,BerteraS,CoronaD,ZerboD,LiVoltiG,EkserB,PuzzoL,RaffaeleM,LoBiancoS,GiaquintaA,VerouxP,VanellaL.BMCSurg.2019Apr24;18(Suppl1):126.EpoxyeicosatrienoicinterventionimprovesNAFLDinleptinreceptordeficientmicebyanincreaseinHO-1-PGC1α-mitochondrialsignaling.RaffaeleM,BellnerL,SinghSP,FaveroG,RezzaniR,RodellaLF,FalckJR,AbrahamNG,VanellaL.ExpCellRes.2019Apr27.pii:S0014-4827(19)30213-7BeneficialEffectsofPomegranatePeelExtractandProbioticsonPre-adipocyteDifferentiation.SorrentiV,RandazzoCL,CaggiaC,BallistreriG,RomeoFV,FabroniS,TimpanaroN,RaffaeleM,VanellaL.FrontMicrobiol.2019Apr3;10:660.N-Acetylcysteine(NAC)AmelioratesLipid-RelatedMetabolicDysfunctioninBoneMarrowStromalCells-DerivedAdipocytes.RaffaeleM,BarbagalloI,LicariM,CarotaG,SferrazzoG,SpampinatoM,SorrentiV,VanellaL.EvidBasedComplementAlternatMed.2018Oct17;2018:5310961DevelopmentofNASHinObeseMiceisConfoundedbyAdiposeTissueIncreaseinInflammatoryNOVandOxidativeStress.SacerdotiD,SinghSP,SchragenheimJ,BellnerL,VanellaL,RaffaeleM,MeissnerA,GrantI,FaveroG,RezzaniR,RodellaLF,BamshadD,LebovicsE,AbrahamNG.IntJHepatol.2018Jul2;2018:3484107.Ablationofsolubleepoxidehydrolasereprogramwhitefattobeige-likefatthroughanincreaseinmitochondrialintegrity,HO-1-adiponectininvitroandinvivo.LiuL,PuriN,RaffaeleM,SchragenheimJ,SinghSP,BradburyJA,BellnerL,VanellaL,ZeldinDC,CaoJ,AbrahamNG.ProstaglandinsOtherLipidMediat.2018Sep;138:1-8.
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HemeOxygenaseInhibitionSensitizesNeuroblastomaCellstoCarfilzomibBarbagalloI,GiallongoC,VoltiGL,DistefanoA,CamioloG,RaffaeleM,SalernoL,PittalàV,SorrentiV,AvolaR,DiRosaM,VanellaL,DiRaimondoF,TibulloD.MolNeurobiol.2019Feb;56(2):1451-1460.doi:10.1007/s12035-018-1133-6.Epub2018Jun10.TheeffectsofoliveleafextractfromaSiciliancultivarinanexperimentalmodelofhepaticsteatosisBarbagalloI,LiVoltiG,RaffaeleM,DistefanoA,PalmeriR,ParafatiL,LicariM,ZingalesV,AvolaR,VanellaL.RendicontiLincei,Volume28,Issue4,1December2017,Pages643-650Metformin:AbridgebetweendiabetesandprostatecancerZingalesV,DistefanoA,RaffaeleM,ZanghiA,BarbagalloI,VanellaL.FrontOncol.2017Oct11;7:243.doi:10.3389/fonc.2017.00243.eCollection2017.Review.
CaffeicAcidPhenethylEsterRestoresAdipocyteGeneProfileExpressionFollowingLipopolysaccharideTreatmentIgnazioBarbagallo,GiovanniLiVolti,ValeriaSorrenti,ClaudiaDiGiacomo,RosariaAcquaviva,MarcoRaffaele,FabioGalvano,LucaVanella.LettersinDrugDesign&Discovery14(4):481-487·February2017AnewantioxidantformulationreducestheapoptoticanddamagingeffectofcigarettesmokeextractonhumanbronchialepithelialcellsVanellaL,LiVoltiG,DistefanoA,RaffaeleM,ZingalesV,AvolaR,TibulloD,BarbagalloI.EuropeanReviewforMedicalandPharmacologicalSciencesVolume21,Issue23,2017,Pages5478-5484(+)-PentazocineattenuatesSH-SY5Ycelldeath,oxidativestressandmicroglialmigrationinducedbyconditionedmediumfromactivatedmicroglia.HeissK,RaffaeleM,VanellaL,MurabitoP,PrezzaventoO,MarrazzoA,AricòG,CastracaniCC,BarbagalloI,ZappalàA,AvolaR,LiVoltiG.NeurosciLett.2017Mar6;642:86-90.NovelCaffeicAcidPhenethylEster(Cape)AnaloguesasInducersofHemeOxygenase-1.PittalàV,VanellaL,SalernoL,DiGiacomoC,AcquavivaR,RaffaeleM,RomeoG,ModicaMN,PrezzaventoO,SorrentiV.CurrPharmDes.2017Feb10.OliveLeafExtractfromSicilianCultivarReducedLipidAccumulationbyInducingThermogenicPathwayduringAdipogenesis.PalmeriR,MonteleoneJI,SpagnaG,RestucciaC,RaffaeleM,VanellaL,LiVoltiG,BarbagalloI.FrontPharmacol.2016May31;7:143.TherapeuticEfficacyofStemCellsTransplantationinDiabetes:RoleofHemeOxygenase.MarcoRaffaele,GiovanniLiVolti,IgnazioA.BarbagalloandLucaVanella.FrontCellDevBiol.2016Aug5;4:80
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Posters27-30/06/2019Asmall-moleculeinhibitorofhemeoxygenase-1enhancesmetforminantiproliferativeactivity.V.Pittalà,M.Raffaele,L.Salerno,A.N.Fallica,V.Ciaffaglione,V.Sorrenti,andL.Vanella11thJointMeetingonMedicinalChemistry2019,Prague24-25/11/2016Roleofnitricoxideinexperimentalmodelofdiabeticnephropathy:effectsofBetulaaetnensisRafinextractAcquavivaR.,TomaselloB.,SorrentiV.,MalfaG.,DiMauroM.,RaffaeleM.,RagusaS.,DiGiacomoC.2ndSino-ItaliansymposiumonBioactiveNaturalProducts–SISBNP2016,Napoli(Internazionale)IauthorizetheprocessingofpersonaldatapursuanttoART.13ofLegislativeDecree196/2003
