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Curriculum Vitae Lise BANKIR French Citizen Professional address : INSERM Unit 1138-E2 Centre de Recherche des Cordeliers and Université Pierre et Marie Curie 15 rue de l'Ecole de Médecine, 75006 Paris, France E-mail: lise.bankir@inserm.fr

Training Baccalaureat (Scientific section) "Licence es Sciences" (Biology) "Doctorat de 3ème Cycle" in Physiology (equivalent to Ph.D.) "Doctorat d'Etat" (French degree higher than Ph.D) Positions

1970 à 2008: Full time investigator at INSERM with the following grades: - 1972-1975 : Attaché de Recherche - 1976-1982 : Chargé de Recherche (equivalent to MR2) - 1983-1986 : Maître de Recherche (equivalent to MR1) - 1986-1993 : Directeur de Recherche (DR2) - 1993-2008 : Directeur de Recherche (DR1) 1986 - 2008 : Head of a Renal Physiology Research Group Since 2008 : Directeur de Recherche Emeritus Research experience in foreign countries 1981: For 9 months, Invited Investigator at the Physiologisches Institut der Univeristät Munich

(Germany). Laboratory of Pr Klaus Thurau. 2001-2002: For 6 months, Invited Investigator in Department of Medicine, University of

California in San Francisco. Laboratory of Alan S. Verkman.

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Memberships

French Societies Société Française de Néphrologie Société Française d'Hypertension Artérielle Société Francophone du Diabète Fonds Français pour l'Alimentation et la Santé American and International Societies American Physiological Society American Society of Nephrology International Society of Nephrology International Society of Nephrology, Education Committee American Heart Association (Kidney Research Council)

Editorial Boards - American Journal of Physiology (1991-1995) (1998-2001) (2001-2002) - News in Physiological Sciences (Associate Editor, 1991-1995) - Kidney International (1995 -1997) - Journal of Nephrology (1993-2003) Awards 1982 : Prix Carré-Bessault from the French Academy of Sciences 2002 : "Michael Kirschenbaum Lecturer", Los Angeles 2005 : Prix Achard-Médecine from the French Academy of Medicine 2011 : Berliner Award from the Renal Section of the Amer. Physiol. Soc. 2011 : Prix Eloy Collery from the French Academy of Medicine 2013 : Prize of the SPA Foundation (Belgium) Mains fields of research

Renal hemodynamics, control of glomerular filtration rate Physiology and pharmacology of vasopressin and/or water intake and their effects

on the kidney Nutritional and hormonal factors involved in progression of chronic renal failure Urinary concentrating mechanism and anatomo-functional correlations in the kidney Development of vasopressin antagonists (in collaboration with drug companies) Influence of of vasopressin or the level of water intake on kidney function and

morphology, consequences in several pathological conditions including kidney disease, hypertension, diabetes mellitus, metabolic syndrome

Present fields of research Contribution of vasopressin to salt-sensitive hypertension Nitrogen metabolism, renal handling of urea, urea transporters, water channels Genetic factors involved in hypertension (in relation to kidney function) Circadian rhythms in water and salt excretion, and blood pressure Role of vasopressin and/or water intake in diabetes mellitus and obesity, and in

diabetic nephropathy

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List of Publications (in inverse chronological order)

From 2000 to March 2015

(see further for papers before 2000)

Taveau C, Chollet C, Waeckel L, Bankir L, et al. Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats. Diabetologia 2015, DOI 10.1007/s00125-015-3496-9.

Roussel R, Fezeu L, Marre M, Bankir L, et al. Comparison between copeptin and vasopressin in a

population from the community and in people with chronic kidney disease. The Journal of clinical endocrinology and metabolism 2014; 99: 4656-4663.

Plischke M, Kohl M, Bankir L, et al. Urine osmolarity and risk of dialysis initiation in a chronic

kidney disease cohort--a possible titration target? PloS one 2014; 9: e93226. Johnson RJ, Rodriguez-Iturbe B, Roncal-Jimenez C, Bankir L, et al. Hyperosmolarity drives

hypertension and CKD--water and salt revisited. Nature reviews Nephrology 2014; 10: 415-420.

Fezeu L, Bankir L, Hansel B, et al. Differential circadian pattern of water and Na excretion rates in

the metabolic syndrome. Chronobiology international 2014; 31: 861-867. Bankir L. Active urea transport in lower vertebrates and mammals. Sub-cellular biochemistry

2014; 73: 193-226.

Dong Z, Ran J, Zhou H, Chen J, Lei T, Wang W, Sun Y, Lin G, Bankir L, Yang B. Urea Transporter UT-B deletion induces DNA damage and apoptosis in mouse bladder urothelium. Plos One 2013, 8(10): e76952. doi:10.1371/journal.pone.0076952

Stenvinkel P, Fröbert O, Anderstam B, Palm F, Eriksson M, Bragfors-Helin AC, Qureshi AR,

Larsson T, Friebe A, Zedrosser A, Josefsson J, Svensson M, Sahdo B, Bankir L, Johnson RJ. Metabolic changes in summer active and anuric hibernating free-ranging brown bears (Ursus arctos). Plos One 2013, 8(9):e72934. doi: 10.1371/journal.pone.0072934

Layton A, Bankir L. Impacts of active urea secretion into pars recta on urine concentration and

urea excretion rate. Physiological Reports 2013, Sep 10;1(3). doi:pii: e00034 Bankir L. Water and kidney physiology. Nutrition Today 2013; 48:S13-S17 Bankir L, Yang B. Urea handling in acute renal failure: The authors' reply. Kidney international

2012; 82: 1137-1138. Bankir L, Bouby N, Ritz E. Vasopressin: a novel target for the prevention and retardation of kidney

disease? (Invited review) Nature Reviews Nephrol. 9: 223–239, 2013

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Velho G, Bouby N, Hadjadj S, Matallah N, Mohammedi K, Fumeron F, Potier L, Bellili-Munoz N, Taveau C, Alhenc-Gelas F, Bankir L, Marre M, Roussel R. Plasma copeptin and renal outcomes in patients with type 2 diabetes and albuminuria. Diabetes Care 2013, 36(11):3639-45

Enhörning S, Bankir L, Bouby N, Struck J, Hedblad B, Persson M, Morgenthaler NG, Nilsson PM,

Melander O. Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmö Diet and Cancer Study cardiovascular cohort. Int J Obes (Lond). 37: 598-603, 2013

Bankir L, Bichet DG. Polycystic kidney disease: An early urea-selective urine-concentrating defect

in ADPKD. Nature Reviews Neph. 8: 437-439, 2012 Coussement J, Danguy C, Zouaoui Boudjeltia K, Defrance P, Bankir L, Biston P, Piagnerelli M.

treatment of the syndrome of inappropriate secretion of antidiuretic hormone by urea in critically ill patients. Am J Nephrol, 35: 265-270, 2012

Bankir L, Yang B. New insights into renal urea handling and the urine concentrating mechanism.

Invited Review. Kidney int. 81: 1179-1198, 2012 Roussel R, Fezeu L, Bouby N, Balkau B, Lantieri O, Alhenc-Gelas F, Marre M, Bankir L; for the

D.E.S.I.R. Study Group. Low water intake and risk for new-onset hyperglycemia. Diabetes Care, 34:2551–2554, 2011

Lei T, Zhou L, Layton AT, Zhou H, Zhao X, Bankir L, Yang B. Role of thin descending limb urea

transport in renal urea handling and the urine concentrating mechanism. Am J Physiol Renal Physiol. 301: F1251–F1259, 2011

Guerrot D, Hansel B, Perucca J, Roussel R, Bouby N, Girerd X, Bankir L. Reduced insulin

secretion and nocturnal dipping of blood pressure are associated with a disturbed circadian pattern of urine excretion in metabolic syndrome. J Clin Endocrinol Metab. 96: E929-E933, 2011

Blanchard A, Frank M, Wuerzner G, Peyrard S, Bankir L, Jeunemaitre X, Azizi M. Antinatriuretic

effect of vasopressin in humans is amiloride-sensitive and thus ENaC-dependent. Clin. J. Am. Soc. Nephrol. 6: 753-759, 2011

Liu L, Lei T, Bankir L, Zhao D, Gai X, Zhao X, Yang B. Erythrocyte permeability to urea and

water: comparative study in rodents, ruminants, carnivores, humans, and birds. J Comp Physiol B: Biochem, Systemic, Environm Physiol. 181: 65-72, 2011

Bankir L, Bichet DG, Bouby N. Vasopressin V2 receptors, ENaC and sodium reabsorption: A risk

factor for hypertension? Am J Physiol Renal Physiol. 299:F917-F928, 2010 Invited Review. Hancock ML, 2nd, Bichet DG, Eckert GJ, Bankir L, Wagner MA, Pratt JH. Race, sex, and the

regulation of urine osmolality: observations made during water deprivation. Am J Physiol Regul Integr Comp Physiol. 299: R977-R980, 2010

Kemter E, Rathkolb B, Bankir L, Schrewe A, Hans W, Landbrecht C, Klaften M, Ivandic B, Fuchs

H, Gailus-Durner V, Hrabé de Angelis M, Wolf E, Wanke R, Aigner B: Mutation of the Na+-

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K+-2Cl- cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia. Am J Physiol Renal Physiol. 298:F1405-F1415, 2010

Torres V, Bankir L, Grantham J: A case for water in the treatment of polycystic kidney disease.

Clinical J. Am. Soc. Nephrol. 4:1140–1150, 2009 Chun T-Y, Bankir L, Eckert GJ, Bichet DG, Saha C, Zaidi S-A, Wagner MA, Pratt JH: Ethnic

Differences in Renal Responses to Furosemide. Hypertension 52: 1-8, 2008 Perucca J, Bichet DG, Bardoux P, Bouby N, Bankir L: Sodium excretion in response to

vasopressin and selective vasopressin receptor antagonists. J. Am. Soc. Nephrol. 19: 1721–1731, 2008

Burnier M, Murielle Bochud M, Bankir L: Response to "Nocturnal Blood Pressure Fall Changes in Correlation With Urinary Sodium Excretion" (Letter to the Editor). Hypertension, 52: e11. Aug 2008

Bankir L, Bochud M, Maillard M, Bovet P, Gabriel A, Burnier M: Nighttime Blood Pressure and

Nocturnal Dipping Are Associated With Daytime Urinary Sodium Excretion in African Subjects. Hypertension 51:891-898, 2008

Perruca J, Bouby N, Valeix P, Jungers P, Bankir L: Différences de concentration urinaire selon le

sexe ou l'origine ethnique: implications possibles dans la susceptibilité variable à différentes pathologies rénales et cardiovasculaires. Néphrologie & Thérapeutique, , 4, 160-172, 2008

Perucca J, Bouby N, Valeix P, Bankir L: Sex difference in urine concentration accross differing

ages, sodium intake and level of kidney disease (Invited review). Am. J. Physiol. Regul. Integrative Physiol. 292: R700-R705, 2007

Bankir L, Perucca J, Weinberger MH: Ethnic differences in urine concentration: possible

relationship to blood pressure. Clin. J. Am. Soc. Nephrol. 2: 304-312, 2007 Gersch MS, Sautin YY, Gersch CM, Henderson G, Bankir L, Johnson RJ: Does Tamm-Horsfall

protein-uric acid binding play a significant role in urate homeostasis? Nephrol. Dial. Transplant. 21: 2938-2942, 2006

Sauter D, Fernandes S, Goncalves-Mendes N, Boulkroun S, Bankir L, Loffing J, Bouby N: Long-

term effects of vasopressin on the subcellular localization of ENaC in the renal collecting system. Kidney Int. 69: 1024-1032, 2006

Zhao D, Bankir L, Qian L, Yang D, Yang B: Urea and urine concentrating ability in mice lacking

AQP1 and AQP3. Am. J. Physiol. Renal Physiol. 291: F429-F438, 2006 Yang B, Bankir L: Urea and urine concentrating ability: new insights from studies in mice. (Invited

review). Am. J. Physiol. Renal Physiol. 288: F871-F886, 2005 Ahoulay M, Bankir L, Lugnier C, Le-Bec A, Poirel O, Moreau R, Lebrec D: Cyclic AMP-

phosphodiesterases inhibitor improves sodium excretion in rats with cirrhosis and ascites. Liver Int. 25: 403-409, 2005

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Bankir L, Fernandes S, Bardoux P, Bouby N, Bichet DG: Vasopressin-V2 receptor stimulaton

reduces sodium excretion in healthy humans. J. Am. Soc. Nephrol. 16: 1920-1928, 2005 Trinh-Trang-Tan MM, Cartron JP, Bankir L: Molecular basis for the dialysis disequlibrium

syndrome: altered aquaporin and urea transporter expression in the brain. Nephrol. Dial. Transplant. 20:1984-1988, 2005

Bankir L, Chan K, Yang B: Lack of UT-B in vasa recta and red blood cells prevents the urea-

induced improvement in urinary concentrating ability. Am. J. Physiol. Renal Physiol. 286: F144-F151, 2004

Bankir L, Sellin F, Maillard M, Chiolero A, Burnier M: Influence of moderate body weight excess

on the nycthemeral pattern of blood pressure, renal function and sodium and water excretion in patients with essential hypertension. Arch. Maladies Coeur Vaisseaux 97:777-781, 2004

Nicco C, Bankir L, Bouby N: Influence of salt and water intake on ENaC abundance in the kidney

of salt-sensitive Sabra rats. Clin. Exp. Pharmacol. Physiol. 30: 963-965, 2003 Schmitt F, Bresson JL, Beressi N, Bichet DG, Chauveau D, Bankir L: Influence of plasma amino

acid level on vasopressin secretion. Diabetes & Metab. 29:352-361, 2003 Bardoux P, Bruneval P, Heudes D, Bouby N, Bankir L: Diabetes-induced albuminuria: role of

antidiuretic hormone as revealed by chronic V2 receptor antagonism in rats. Nephrol. Dial. Transplant. 18:1755-1763, 2003

Bardoux P, Bichet DG, Martin H, Gallois Y, Marre M, Bouby N, Bankir L: Vasopressin increases

urinary albumin excretion in rats and humans: involvement of V2 receptors and the renin-angiotensin system. Nephrol. Dial. Transplant. 18: 497-506, 2003

Schmidt-Nielsen B, Bankir L: Dilution of urine through renal fluid secretion: anatomo-functional

convergence in marine elasmobranchs and oligochetes. Bull. Mount Desert Island Biol. Lab. 42:2-9 2003

Yang B, Bankir L, Gillepsie A, Epstein CJ, Verkman AS: Urea-selective concentrating defect in

transgenic mice lacking urea transporter UT-B. J. Biol. Chem. 277:10633-10637, 2002 Bankir L, Bardoux P, Mayaudon H, Dupuy O, Bauduceau B: Débit urinaire trop bas le jour mais

élevé la nuit:un nouveau facteur pouvant contribuer à l'hypertension et à l'absence de "dipping" nocturne.

Archives des Maladies du Coeur et des Vaisseaux, 95:751-754, 2002 Nicco C, Wittner M, DiStefano A, Jounies S, Bankir L, Bouby N: Chronic exposure to vasopressin

upregulates ENaC and sodium transport in the rat collecting duct. Hypertension 38:1143-1149, 2001

Bardoux P, Ahloulay M, LeMaout S, Bankir L, Trinh-Trang-Tan MM: Aquaporin 2 and urea

transporter-A1 are upregulated in rats with type I diabetes mellitus. Diabetologia 44:637-645, 2001

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Pouzet B, Serradeil-Le-Gal C, Bouby N, Maffrand JP, Le-Fur G, Bankir L: Selective blockade of

vasopressin V2 receptors reveals significant V2-mediated water reabsorption in Brattleboro rats with diabetes insipidus. Nephr. Dialysis, Transplant. 16:725-734, 2001

Bankir L, Ahloulay M, Devreotes P, Parent C: Extracellular cyclic AMP inhibits proximal

reabsorption: are plasma membrane cAMP receptors involved? (Invited Review). Am. J. Physiol. Renal Physiol. 282: F376-F392., 2002

Bankir L: Antidiuretic action of vasopressin: quantitative aspects and interaction between V1a

and V2 receptor-mediated effects (Invited Review). Cardiovasc. Res. 51:372-390, 2001 Bankir L, Ahloulay M, Bardoux P: Vasopressin and diabetes mellitus (Distinguished Scientists

Lecture Series). Nephron 87: 8-18, 2001 Bankir L, Bouby N: Renal excretion of urea, in: Textbook of Nephrology (4th Edition), edited by

Massry S G, Glassock R J, Philadelphia, Lippincott Williams & Wilkins, 2001, pp. 82-87 Hu MC, Bankir L, Rousselet G, Trinh-Trang-Tan MM: Massive reduction of urea transporters in

remnant kidney and brain of uremic rats. Kidney Int. 58: 1202-1210, 2000 Nicco C, Martin H, Yagil C, Yagil Y, Bankir L, Bouby N: Regulation by sodium intake or type 1

angiotensin II receptor mRNAs in the kidney of Sabra rats. J. Hypertension 18: 1097-1105, 2000

Bankir L, Trinh-Trang-Tan MM: Renal urea transporters: Direct and indirect regulation by

vasopressin. Exp. Physiol. 85 (Suppt): 243-252, 2000 Bankir L, Trinh-Trang-Tan MM: Urea and the kidney, in: The Kidney (6th Edition), edited by

Brenner B M, Philadelphia, W B Saunders Company, 2000, pp. 637-679

1971 - 1999 (Main papers only) Ahloulay M, Schmitt F, Déchaux M, Bankir L: Vasopressin and urinary concentrating activity in

diabetes mellitus. Diabetes & Metabolism 25: 213-222, 1999 Bardoux P, Martin H, Ahloulay M, Schmitt F, Bouby N, Trinh-Trang-Tan MM, Bankir L:

Vasopressin contributes to hyperfiltration, albuminuria, and renal hypertrophy in diabetes mellitus : study in vasopressin-deficient Brattleboro rats. Proc. Natl. Acad. Sci. USA 96: 10397-10402, 1999

Bouby N, Hassler C, Bankir L: Contribution of vasopressin to progression of chronic renal failure:

study in Brattleboro rats infused with AVP or dDAVP. Life Sciences 65: 991-1004, 1999 Brand E, Bankir L, Plouin PF, Soubrier F: Glucagon receptor gene mutation (Gly40Ser) in human

essential hypertension: the PEGASE study. Hypertension 34: 15-17, 1999

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Hu MC, Bankir L, Trinh-Trang-Tan MM: mRNA expression of renal urea transporters in normal and Brattleboro rats: effects of dietary protein intake. Exp. Nephrol. 7: 44-51, 1999

Promeneur D, Bankir L, Hu MC, Trinh-Trang-Tan MM: Renal tubular and vascular urea

transporters: influence of antidiuretic hormone on mRNA expression in Brattleboro rats. J. Am. Soc. Nephrol. 9: 1359-1366, 1998

Bankir L, Trinh-Trang-Tan MM: Urea excretion revisited: physiology and transporters, in:

Advances in Nephrology from the Necker Hospital (vol. 28), edited by Grünfeld J P, Bach J F, Kreis H, Broneer D, Maxwell M H, St Louis, Mosby, 1998, pp. 83-135

Same paper published in French: Bankir L, Trinh-Trang-Tan MM: L'urée revisitée: physiologie, pathologie et apports récents de la

biologie moléculaire, in: Actualités Néphrologiques Jean Hamburger (Hôpital Necker), edited by Grünfeld J P, Bach J F, Kreis H, Paris, Flammarion-Médecine Sciences, 1998, pp. 67-107

Trinh-Trang-Tan MM, Bankir L: Integrated function of urea transporters in the mammalian kidney

(Invited Review). Exp. Nephrol. 6: 471-479, 1998 Bouby N, HusCitharel A, Marchetti J, Bankir L, Corvol P, LlorensCortes C: Expression of type 1

angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron. J. Am. Soc. Nephrol. 8: 1658-1667, 1997

Choukroun G, Schmitt F, Martinez F, Drüeke T, Bankir L: Low urine flow rate reduces the

capacity to excrete a sodium load in man. Am. J. Physiol. (Regulatory, Integrative and Comp. Physiol. 42) 273: R1726-R1733, 1997

El-Marjou A, Bankir L, Pierrat D, Trinh-Trang-Tan MM: Messenger RNA for enzymes of ornithine

and polyamine metabolism are selectively underexpressed in kidney of 5/6 nephectomized rats. Exp. Nephrol. 5: 285-294, 1997

Bankir L: Vasopressin and water conservation: the good and the evil. Am. J. Kidney Diseases

30: XLIV-XLVI, 1997 Bankir L, Martin H, Déchaux M, Ahloulay M: Plasma cyclic AMP: an interorgan mediator

regulating water and sodium excretion. Kidney Int. 51 (Suppl. 59): S.50-S.56, 1997 Bankir L: Urea and the kidney, in: The Kidney (5th Edition), edited by Brenner B M, Rector F C,

Philadelphia, W B Saunders Company, 1996, pp. 571-606 Ahloulay M, Déchaux M, Hassler C, Bouby N, Bankir L: Cyclic AMP is a hepatorenal link

influencing natriuresis and contributing to glucagon-induced hyperfiltration in rats. J. Clin. Invest. 98: 2251-2258, 1996

Bankir L, Bouby N, Trinh-Trang-Tan MM, Ahloulay M, Promeneur D: Direct and indirect cost of

urea excretion. Kidney Int. 49: 1598-1607, 1996 Bouby N, Ahloulay M, Nsegbe E, Déchaux M, Schmitt F, Bankir L: Vasopressin increases GFR in

conscious rats through its antidiuretic action. J. Am. Soc. Nephrol. 7: 842-851, 1996

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Bouby N, Bankir L, Llorens-Cortes C: Type 1 angiotensin II receptor subtypes in kidney of normal and salt-sensitive hypertensive rats. Hypertension 27: 392-398, 1996

Promeneur D, Rousselet G, Bankir L, Bailly P, Cartron JP, Ripoche P, Trinh-Trang-Tan MM:

Evidence for distinct vascular and tubular urea transporters in the rat kidney. J. Am. Soc. Nephrol. 7: 852-860, 1996

Serradeil-Le-Gal C, Lacour C, Valette G, Garcia G, Foulon L, Galindo G, Bankir L, Pouzet B,

Guillon G, Barberis C, Chicot D, Jard S, Vilain P, Garcia C, Marty E, Raufaste D, Brossard G, Nisato D, Maffrand JP, Le-Fur G: Charaterization of SR 121463A, a highly potent and selective orally active vasopressin V2 receptor antagonist. J. Clin. Invest. 98: 2729-2738, 1996

Bankir L, Kriz W: Adaptation of the kidney to protein intake and to urine concentrating activity:

similar consequences in health and disease (Editorial Review). Kidney Int. 47: 7-24, 1995 Lang F, Öttl I, Haüssinger D, Deetjen P, Ahloulay M, Bankir L: Renal hemodynamic response to

intravenous and oral amino acids in animals. Semin. Nephrol. 15: 415-418, 1995 Ahloulay M, Déchaux M, Laborde K, Bankir L: Influence of glucagon on GFR and on urea and

electrolyte excretion: direct and indirect effects. Am. J. Physiol. Renal Fluid and Electrolyte Physiol. 269: 225-235, 1995

Choukroun G, Bankir L, Trinh-Trang-Tan MM: Effect of chronic renal failure on the abundance of

mRNA for enzymes of the intermediary metabolism in kidney and liver. Experim Nephrol 2: 358-363, 1994

Bankir L, Ahloulay M, Bouby N, Machet F, Trinh-Trang-Tan MM: Direct and indirect effects of

vasopressin on renal hemodynamics, in: Vasopressin, edited by Gross P, Richter D, Robertson G L, Paris, John Libbey Eurotext, 1993, pp. 393-406

Bankir L, Ahloulay M, Bouby N, Trinh-Trang-Tan MM, Machet F, Lacour B, Jungers P: Is the

process of urinary urea concentration responsible for a high glomerular filtration rate? (Editorial Review). J Am Soc Nephrol 4: 1091-1103, 1993

Bouby N, Hassler C, Parvy P, Bankir L: Renal synthesis of arginine in chronic renal failure: in vivo

and in vitro study in rats with 5/6 nephrectomy. Kidney Int 44: 676-683, 1993 Levillain O, Hus-Citharel A, Morel F, Bankir L: Arginine synthesis in the mouse and rabbit

nephron: localization and functional significance. Am J Physiol 264 (Renal, Fluid and Electrolyte Physiol. 33): F1038-F1045, 1993

Trinh-Trang-Tan MM, Antras J, Levillain O, Bankir L: Adaptation of the medullary thick ascending

limb to dietary protein intake. Exp Nephrol 1: 158-167, 1993 Ahloulay M, Bouby N, Machet F, Kubrusly M, Coutaud C, Bankir L: Effects of glucagon on GFR

and on urea and water excretion. Am J Physiol 263 (Renal, Fluid, Electrolyte Physiol. 32): F24-F36, 1992

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Bouby N, Coutaud C, Bankir L: Arginine synthesis by the proximal convoluted tubule in rats with chronic renal failure. Mineral Electr Metab 18: 101-103, 1992

Elger M, Bankir L, Kriz W: Morphometric analysis of kidney hypertrophy in rats after chronic

potassium depletion. Am J Physiol 262 (Renal Fluid Electrolyte Physiol 31): F656-F667, 1992

Hadj-Aissa A, Bankir L, Fraysse M, Bichet DG, Laville M, Zech P, Pozet N: Influence of the level

of hydration on the renal response to a protein meal. Kidney Int 42: 1207-1216, 1992 Levillain O, Hus-Citharel A, Morel F, Bankir L: Localization of urea and ornithine production along

the mouse and rabbit nephron. Functional significance. Am J Physiol 263 (Renal, Fluid and Electrolyte Physiol. 32): F878-F885, 1992

Bachmann S, Dawnay ABS, Bouby N, Bankir L: Tamm-Horsfall protein excretion during chronic

alterations in urinary concentration and protein intake in the rat. Renal Physiol Biochem 14: 236-245, 1991

Bankir L: Vasopressin and the urinary concentrating mechanism, in: Vasopressin, edited by Jard

S, Jamison R, Colloque INSERM/John Libbey Eurotext Ltd, 1991, pp. 437-447 Bankir L, Bouby N: Vasopressin and urinary concentration : Additional risk factors in the

progression of chronic renal failure. Am J Kidney Dis 17 (suppl 1): 20-26, 1991 Bankir L, Bouby N, Trinh-Trang-Tan MM: Vasopressin-dependent kidney hypertrophy. Role of

urinary concentration in the protein-induced kidney hypertrophy and in the progression of chronic renal failure. Am J Kidney Dis 17: 661-665, 1991

Bouby N, Trinh-Trang-Tan MM, Coutaud C, Bankir L: Vasopressin is involved in the renal effects

of high protein diet : study in homozygous Brattleboro rats. Am J Physiol 260 (Renal Fluid Electrolyte Physiol. 29): F96-F100, 1991

Oudar O, Elger M, Bankir L, Ganten D, Ganten D, Kriz W: Differences in rat kidney morphology

between males, females and testosterone treated females. Renal Physiol Biochem 14: 92-102, 1991

Bouby N, Bachmann S, Bichet D, Bankir L: Effect of water intake on the progression of chronic

renal failure in the 5/6 nephrectomized rat. Am J Physiol (Renal Fluid Electrolyte Physiol 27) 258: F973-F979, 1990

Kim JK, Soubrier F, Michel JB, Bankir L, Corvol P, Schrier RW: Arginine vasopressin gene

regulation in the homozygous Brattleboro rat. J Clin Invest 86: 14-16, 1990 Levillain O, Hus-Citharel A, Morel F, Bankir L: Localization of arginine synthesis along the rat

nephron. Am J Physiol 259 (Renal Fluid Electrolyte Physiol. 28): F916-F923, 1990 Bankir L, Bouby N, Trinh-Trang-Tan MM: The role of the kidney in the maintenance of water

balance. Baillière's Clin Endocrinol Metab 3: 249-311, 1989

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Bankir L, Bouby N, Trinh-Trang-Tan MM: Possible involvement of vasopressin and urine concentrating process in the progression of chronic renal failure. Kidney Int 36 Supp 27: S32-S37, 1989

Levillain O, Hus-Citharel A, Morel F, Bankir L: Production of urea from arginine in pars recta and

collecting duct of the rat kidney. Renal Physiol Biochem 12: 302-312, 1989 Schrier RW, Kim JK, Soubrier F, Michel JB, Bankir L, Corvol P: Arginine vasopressin gene

regulation in the homozygous Brattleboro rat, in: Recent progress in posterior pituitary hormones, edited by Yoshida S, Share L, Elsevier Science Publishers, 1988, pp. 215-218

Bankir L, Fischer C, Fischer S, Jukkala K, Specht HC, Kriz W: Adaptation of the rat kidney to

altered water intake and urine concentration. Pflügers Archiv 412: 42-53, 1988 Bouby N, Bankir L: Effect of high protein intake on sodium, potassium dependent adenosine

triphosphatase activity in the thick ascending limb of Henle's loop in the rat. Clin Sci 74: 319-329, 1988

Bouby N, Tring-Trang-Tan MM, Laouari D, Kleinknecht C, Grünfeld JP, Kriz W, Bankir L: Role of

the urinary concentrating process in the renal effects of high protein intake. Kidney Int 43: 4-12, 1988

Kriz W, Bankir L: A standard nomenclature for structures of the kidney (Published simultaneously

in several journals, and later, in books). Am J Physiol 254:F1-F7; Pflugers Arch 411:113-120; Kidney Int 33:1-7; Anat Embryol 178:N1-N8 1988

Trinh-Trang-Tan MM, Levillain O, Bankir L: Contribution of leucine to oxidative metabolism of the

rat medullary thick ascending limb. Pflügers Archiv 411: 676-680, 1988 Bankir L, Bouby N, Trinh-Trang-Tan MM: Heterogeneity of nephron anatomy. Kidney Int 31 Sup

20: S25-S39, 1987 Bankir L, Bouby N, Trinh-Trang-Tan MM, Kaissling B: Thick ascending limb of Henle's loop :

anatomy and function, role in urine concentrating mechanisms, in: Advances in Nephrology, edited by Grünfeld J P, Year Book Medical Publishers, 1987, pp. 69-102

Bouby N, Trinh-Trang-Tan MM, Kriz W, Bankir L: Possible role of the thick ascending limb and of

the urine concentrating mechanism in the the protein-induced increase in GFR and kidney mass. Kidney Int 32 Supp 22: S.57-S.61, 1987

Trinh-Trang-Tan MM, Bouby N, Kriz W, Bankir L: Functional adaptation of thick ascending limb

and internephron heterogeneity to urine concentration. Kidney Int 31: 549-555, 1987 Trinh-Trang-Tan MM, Bouby N, Coutaud C, Bankir L: Quick isolation of rat medullary thick

ascending limbs. Enzymatic and metabolic characterization. Pflügers Archiv 407: 228-234, 1986

Bankir L, Bouby N, Trinh-Trang-Tan MM, Kaissling B: La branche large ascendante de l'anse de

Henle: caractéristiques anatomiques et fonctionnelles et rôle dans le mécanisme de

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concentration de l'urine, in: Actualités Néphrologiques de l'Hôpital Necker, edited by Grünfeld J P, Flammarion Médecine-Sciences, 1986, pp. 66-69

Bankir L, Bouby N, Trinh-Trang-Tan MM, Kriz W, Grünfeld JP: Effects of long-term presence or

absence of vasopressin on kidney function and morphology, in: Vasopressin, edited by Schrier R W, Raven Press, 1985, pp. 497-506

Bankir L, Rouffignac-de C: Urinary concentrating ability : Insights from comparative anatomy

(Editorial review). Am J Physiol 249 (Regulatory Integr. Comp. Physiol. 18): R643-R666, 1985

Bouby N, Bankir L, Trinh-Trang-Tan MM, Minuth WW, Kriz W: Selective ADH-induced

hypertrophy of the medullary thick ascending limb in Brattleboro rats. Kidney Int 28: 456-466, 1985

Trinh-Trang-Tan MM, Bankir L, Doucet A, El-Mernissi G, Imbert-Teboul M, Montegut M, Siaume

S, Morel F: Influence of chronic ADH treatment on adenylate cyclase and Na-K-ATPase activity in diabetes insipidus Brattleboro rats. Pflügers Archiv 405: 216-222, 1985

Bankir L, Bouby N, Trinh-Trang-Tan MM: Organization of the medullary circulation : Functional

implications, in: Nephrology, Proc IXth Int Cong Nephrol, edited by Robinson R R, Springer Verlag, 1984, pp. 84-106

Bouby N, Trinh-Trang-Tan MM, Bankir L: Stimulation of magnesium and calcium tubular

reabsorption by antidiuretic hormone in conscious rats. Study in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Pflügers Archiv 402: 458-464, 1984

Bouby N, Trinh-Trang-Tan MM, Douté M, Bankir L: Effects of osmolality and antidiuretic hormone

on prostaglandin sythesis by the renal papilla. Study in Brattleboro rats with diabetes insipidus. Pflügers Archiv 400: 96-99, 1984

Trinh-Trang-Tan MM, Bouby N, Douté M, Bankir L: Effects of long-term and short-term

antidiuretic hormone availability on internephron heterogeneity in the adult rat. Am J Physiol 246: F879-F888, 1984

Bankir L, Hollenberg NK: In vivo staining of the kidney with Alcian Blue : an adjunct to

morphological and physiological studies. Renal Physiol 6: 151-155, 1983 Eloy L, Grünfeld JP, Bayle F, Bankir L, Ramos-Frendo B, Trinh-Trang-Tan MM: Papillary plasma

flow in rats. II. Hormonal control. Pflügers Archiv 398: 253-258, 1983 Bayle F, Eloy L, Trinh-Trang-Tan MM, Grünfeld JP, Bankir L: Papillary plasma flow in rats.

Relation to urine osmolality in normal and Brattleboro rats with hereditary diabetes insipidus. Pflügers Archiv 394: 211-216, 1982

Rouffignac-de C, Bankir L, Roinel N: Renal function and concentrating ability in a desert rodent,

the Gundi (Ctenodatylus vali). Pflügers Archiv 390: 138-144, 1981 Trinh-Trang-Tan MM, Diaz M, Grünfeld JP, Bankir L: ADH-dependent nephron heterogeneity in

rats with hereditary hypothalamic diabetes insipidus. Am J Physiol 240: F372-F380, 1981

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Bankir L, Trinh-Trang-Tan MM, Nivez MP, Sraer J, Ardaillou R: Altered PGE2 production by

glomeruli and papilla of rats with hereditary hypothalamic diabetes insipidus. Prostaglandins 20: 349-366, 1980

Bankir L, Kaissling B, Rouffignac-de C, Kriz W: The vascular organization of the kidney of

Psammomys obesus. Anat Embryol 155: 149-160, 1979 Bankir L, Trinh-Trang-Tan MM, Grünfeld JP: Measurement of glomerular blood flow in rabbits

and rats : erroneous findings with 15 µm microspheres. Kidney Int 15: 126-133, 1979 Sabto J, Bankir L, Grünfeld JP: The measurement of glomular blood flow in the rat kidney.

Influence of microsphere size. Clin Exp Pharmacol Physiol 5: 559-566, 1978 Bankir L, Rouffignac-de C: Anatomical and functional heterogeneity of nephrons in the rabbit

kidney : microdissection studies and SNGFR measurements. Pflügers Archiv 366: 89-93, 1976

Bankir L, Rouffignac-de C, Grünfeld JP, Sabto J, Funck-Brentano JL: Single glomerular blood

flow and single nephron glomerular filtration rate in the hydropenic rabbit kidney, in: Proc Int Symp Radionuclides in Nephrology, Georg Thieme Verlag, 1975, pp. 2-8

Bankir L, Farman N, Grünfeld JP, Huet-de-la-Tour E, Funck-Brentano JL: Radioactive

microsphere distribution and single glomerular blood flow in the normal rabbit kidney. Pflügers Archiv 342: 111-123, 1973

Hamburger J, Dimitriu A, Bankir L, Debray-Sachs M, Auvert J: Collection of lymph from kidney

homotransplanted in man. Cell transformation in vivo. Nature (London) 232: 633, 1971