CURRICULUM VITAE

A. IDENTIFYING DATAName Aaron D. Gitler, Ph.D.Last Edited: February, 2017

B. ACADEMIC HISTORY

Education:

2000 B.S. (Science), Penn State University (Advisor: Dr. Graham Thomas)2004 Ph.D. (Cell and Molecular Biology), University of Pennsylvania School of Medicine

(Advisor: Dr. Jonathan Epstein)

Postdoctoral Fellowship Training:

2004 – 2007 Whitehead Institute for Biomedical Research (Advisor: Dr. Susan Lindquist)

C. EMPLOYMENT HISTORY

Academic Appointments:

2007 – 2011 Assistant Professor of Cell and Developmental Biology, University of Pennsylvania School of Medicine

2012 – Associate Professor of Genetics, Stanford University School of Medicine

D. PUBLIC AND PROFESSIONAL SERVICES

Advisory Board Service

2012 – 2013 Novartis Neuroscience Advisory Council member2013 – present Packard Center for ALS Research Scientific Advisory Board member2013 – present NIH Cellular and Molecular Biology of Neurodegeneration Study Section

(CMND), Standing Member2016 – present Society for Neuroscience Program Committee member2017 – present Biology and Medicine Panel of the Hong Kong Research Grants Council

Editorial Board Service

2015 – present Molecular Neurodegeneration Editorial Board member

Grant Review Service

2008 Motor Neurone Disease Association2008 Parkinson’s Disease Society2009-2014 American Federation for Aging Research (AFAR)2009 NIH Challenge Grants in Health and Science Research (RC1), Ad hoc

2010, 2012, 2013 NIH Cellular and Molecular Biology of Neurodegeneration Study Section (CMND), Ad hoc

2011 NIH Special Emphasis Panel (MDCN), Ad hoc2011, 2012 Thierry Latran Foundation (Belgium)2011 Israel Science Foundation2012 ALS Association (ALSA)2011, 2012 AriSLA (Italy)2013 – present NIH Cellular and Molecular Biology of Neurodegeneration Study Section

(CMND), Standing Member2015 Brain Canada – ALS Canada Review Panel

E. HONORS AND AWARDS

1997 Howard Hughes Medical Institute Undergraduate Research Fellowship, Penn State University

2002 Cell and Developmental Biology Department Predoctoral Training Grant, University of Pennsylvania

2003 Cell and Molecular Biology Graduate Group Outstanding Poster Award2004 Keystone Symposia Scholarship Winner – Cardiac Development Meeting2004 Nachmias/Thimann Prize for Outstanding Graduate Student Research, CDB, University

of Pennsylvania2004 NF Prize for Research Ideas, 2nd Prize – The National Neurofibromatosis Foundation2005 Saul Winegrad, M.D. Award for Outstanding Dissertation2005 Top 5 Dissertations Nationally – Council of Graduate Schools Distinguished

Dissertation Award2005 Life Sciences Research Foundation Postdoctoral Fellowship2007 University of Pennsylvania McCabe Fund Fellow Award2008 Pew Scholar in the Biomedical Sciences2008 Ellison Medical Foundation New Scholar Award in Aging (Declined)2008 NIH Director’s New Innovator Award2009 Rita Allen Foundation Scholar2010 “Scientist to Watch,” Aug. 2010, The Scientist2011 Addgene Innovation Award Winner2011 Instituto Paulo Gontijo International Medicine PG Award for best ALS research by a

young investigator2011 Eppendorf and Science Prize for Neurobiology, Finalist2013 International Society for Neurochemistry Young Scientist Lectureship Award2015 Glenn Award for Research in Biological Mechanisms of Aging2016 NIH NINDS R35 Research Program Award

F. BIBLIOGRAPHY

Peer-reviewed Journal Articles (75 total; 73 published, 2 in press):

1. Gunatilaka, A.A., V.J. Paul, P.U. Park, M.P. Puglisi, A.D. Gitler, D.S. Eggleston, R.C. Haltiwanger, and D.G. Kingston, Apakaochtodenes A and B: two tetrahalogenated

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monoterpenes from the red marine alga Portieria hornemannii. J Nat Prod, 1999. 62(10): p. 1376-8.

2. Lu, M.M., F. Chen, A. Gitler, J. Li, F. Jin, X.K. Ma, and J.A. Epstein, Cloning and expression analysis of murine lupin, a member of a novel gene family that is conserved through evolution and associated with Lupus inclusions. Dev Genes Evol, 2000. 210(10): p. 512-7.

3. Chen, F., H. Kook, R. Milewski, A.D. Gitler, M.M. Lu, J. Li, R. Nazarian, R. Schnepp, K. Jen, C. Biben, G. Runke, J.P. Mackay, J. Novotny, R.J. Schwartz, R.P. Harvey, M.C. Mullins, and J.A. Epstein, Hop is an unusual homeobox gene that modulates cardiac development. Cell, 2002. 110(6): p. 713-23.

4. Gitler, A.D., M.M. Lu, Y.Q. Jiang, J.A. Epstein, and P.J. Gruber, Molecular markers of cardiac endocardial cushion development. Dev Dyn, 2003. 228(4): p. 643-50.

5. Gitler, A.D.*, Y. Zhu*, F.A. Ismat, M.M. Lu, Y. Yamauchi, L.F. Parada, and J.A. Epstein, Nf1 has an essential role in endothelial cells. Nat Genet, 2003. 33(1): p. 75-9. * These authors contributed equally

6. Kochilas, L.K., V. Potluri, A. Gitler, K. Balasubramanian, and A.J. Chin, Cloning and characterization of zebrafish tbx1. Gene Expr Patterns, 2003. 3(5): p. 645-51.

7. Kook, H., J.J. Lepore, A.D. Gitler, M.M. Lu, W. Wing-Man Yung, J. Mackay, R. Zhou, V. Ferrari, P. Gruber, and J.A. Epstein, Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop. J Clin Invest, 2003. 112(6): p. 863-71. PMCID: PMC193673

8. Gitler, A.D.*, Y. Kong*, J.K. Choi, Y. Zhu, W.S. Pear, and J.A. Epstein, Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia. Pediatr Res, 2004. 55(4): p. 581-4. (Featured on the cover). * These authors contributed equally

9. Gitler, A.D., M.M. Lu, and J.A. Epstein, PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev Cell, 2004. 7(1): p. 107-16.

10. Torres-Vazquez, J.*, A.D. Gitler*, S.D. Fraser*, J.D. Berk, N.P. Van, M.C. Fishman, S. Childs, J.A. Epstein, and B.M. Weinstein, Semaphorin-plexin signaling guides patterning of the developing vasculature. Dev Cell, 2004. 7(1): p. 117-23. * These authors contributed equally

11. Engleka, K.A., A.D. Gitler, M. Zhang, D.D. Zhou, F.A. High, and J.A. Epstein, Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Dev Biol, 2005. 280(2): p. 396-406.

12. Cooper, A.A.*, A.D. Gitler*, A. Cashikar, C. Haynes, K. Hill, B. Bhullar, K. Liu, K. Xu, K.E. Strathearn, F. Liu, S. Cao, K.A. Caldwell, G.A. Caldwell, G. Marsischky, J. LaBaer, R.D. Kolodner, J.C. Rochet, N.M. Bonini, and S. Lindquist, Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science, 2006. 313:324-328. * These authors contributed equally. PMCID: PMC1983366

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13. Wu J, M. O'Donnell, A.D. Gitler, P.S. Klein, Kermit 2/XGIPC, an IGF1 receptor interacting protein, is required for IGF signaling in Xenopus eye development. Development, 2006, 133(18):3651-60.

14. Alberti, S.*, A.D. Gitler*, S. Lindquist, A suite of yeast Gateway vectors for high-throughput genetic analysis. Yeast, 2007, 24(10):913-9. * These authors contributed equally. PMCID: PMC2190539

15. Gitler, A.D., Beer and bread to brains and beyond: Can yeast cells teach us about neurodegenerative disease? NeuroSignals, 2008, 16:52–62. (Featured on the cover)

16. Gitler, A.D.*, Bevis, B.J.*, J. Shorter, K. Strathearn, S. Hamamichi, J. Su, K.A. Caldwell, G.A. Caldwell, J.C. Rochet, J.M. McCaffery, C. Barlowe, S. Lindquist, The Parkinson’s disease protein synuclein disrupts cellular Rab homeostasis. Proc Natl Acad Sci USA, 2008, 1:145-50. * These authors contributed equally. PMCID: PMC2224176

17. Johnson B.S., J.M. McCaffery, S. Lindquist, A.D. Gitler, A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proc Natl Acad Sci USA, 2008, 17:6439-44. PMCID: PMC2359814

18. Sun, Z. and A.D. Gitler, Discovery and characterization of three novel synuclein genes in zebrafish. Dev Dyn, 2008 237(9):2490-2495. (Featured on the cover)

19. Rappley, I., A.D. Gitler, P. Selvy, M. LaVoie, B. Levy, H.A. Brown, S. Lindquist, D.J. Selkoe, Evidence that Synuclein Does Not Inhibit Phospholipase D. Biochemistry, 2009. 48 (5):1077-83. PMCID: PMC2683767

20. Gitler, A.D.*, A. Chesi*, M.L. Geddie*, K.E. Strathearn, S. Hamamichi, K.J. Hill, K.A. Caldwell, G.A. Caldwell, A.A. Cooper, J.C. Rochet, S. Lindquist, Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat Genet, 2009. 41(3): p. 308-15. * These authors contributed equally. PMCID: PMC2683786

21. Yeger-Lotem, E., L. Riva, L.J. Su, A.D. Gitler, A. Cashikar, O.D. King, P.K. Auluck, M.L. Geddie, D.R. Karger, S. Lindquist, E. Fraenkel, Bridging genetic and transcriptional data via the interactome reveals response pathways and Parkinson’s mechanisms. Nat Genet, 2009. 41(3): p. 316-23. PMCID: PMC2733244

22. Johnson, B.S., D. Snead, J.J. Lee, J.M. McCaffery, J. Shorter*, A.D. Gitler*, TDP-43 is intrinsically aggregation-prone and ALS-linked mutations accelerate aggregation and increase toxicity. J Biol Chem, 2009. 284(30): p. 20329-20339. * Co-corresponding authors. PMCID: PMC2740458

23. Xiong, Y., C.E. Coombes, A. Kilaru, A.D. Gitler, W.J. Bowers, V.L. Dawson, T.M. Dawson, D.J. Moore, GTPase Activity Plays a Key Role in the Pathobiology of LRRK2. PLoS Genet, 2010. 6(4): p. e1000902. PMCID: PMC2851569

24. Cushman*, M., B.S. Johnson*, O.D. King, A.D. Gitler#, J. Shorter#, Prion-like disorders: blurring the divide between transmissibility and infectivity. J Cell Sci, 2010. 123(8):1191-1201. * These authors contributed equally, #Co-corresponding authors. PMCID: PMC2848109

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25. Elden, A.C.*, H.J. Kim*, M.P. Hart*, A.S. Chen-Plotkin*, B.S. Johnson, X. Fang, M. Armakola, F. Geser, R. Greene, M. Lu, A. Padmanabhan, D. Clay, L. McCluskey, L. Elman, D. Juhr, P.J. Gruber, U. Rüb, G. Auburger, J.Q. Trojanowski, V. M.-Y. Lee, V.M. Van Deerlin, N.M. Bonini#, AD. Gitler#, Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature, 2010. 466(7310):1069-1075. *These authors contributed equally, #Co-corresponding authors. PMCID: PMC217752

26. Armakola, M., M.P. Hart, A.D. Gitler, TDP-43 toxicity in yeast. Methods, 2011. 53(3):238-245. PMCID: PMC3073690

27. Lee, T., Y.R. Li, C. Ingre, M. Weber, T. Grehl, O. Gredal, M. de Carvalho, T. Meyer, O. Tysnes, G. Auburger, S. Gispert, N.M. Bonini, P.M. Andersen, A.D. Gitler, Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients. Hum Mol Genet, 2011. 20(9):1697-1700. (Featured on the cover). PMCID: PMC3071667

28. Lee, T., Y.R. Li, A. Chesi, M.P. Hart, D. Ramos, N. Jethava, D. Hosangadi, J. Epstein, B. Hodges, N.M. Bonini#, A.D. Gitler#, Evaluating trinucleotide repeat expansions in ALS. Neurology, 2011. 6(24):2062-2065.#Co-corresponding authors. PMCID: PMC3111240

29. Yu, Z., Y. Zhu, A.S. Chen-Plotkin, J.Q. Trojanowski, V.M.-Y. Lee, V.M. Van Deerlin, A.D. Gitler#, N.M. Bonini#, PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted. PLoS One, 2011. 6(3): e17951. #Co-corresponding authors. PMCID: PMC3066214

30. Sun, Z.*, Z. Diaz*, X. Fang, M.P. Hart, M. Armakola, A. Chesi, J. Shorter#, A.D. Gitler#, Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. PLoS Biol, 2011. 9(4): e1000614. *These authors contributed equally, #Co-corresponding authors. PMCID: PMC3082519

31. Konopka C.A., M.N. Locke, P.S. Gallagher, N. Pham, M.P. Hart, C.J. Walker, A.D. Gitler, R.G. Gardner. A yeast model for polyalanine-expansion aggregation and toxicity. Mol Biol Cell, 2011. 22(12):1971-1984. PMCID: PMC3113764

32. Fleming, M. and A.D. Gitler, High-throughput yeast plasmid overexpression screen. J Vis Exp, 2011. (53). pii: 2836. doi: 10.3791/2836.

33. Gitler A.D.# and J. Shorter#, RNA-binding proteins with prion-like domains in ALS and FTLD-U. Prion, 2011. 5(3): 179-187. #Co-corresponding authors. PMCID: PMC3226045

34. Gispert S., A. Kurz, S. Waibel, P. Bauer, I. Liepelt, C. Geisen, A.D. Gitler, T. Becker, M. Weber, D. Berg, P.M. Andersen, R. Krüger, O. Riess, A.C. Ludolph, G. Auburger, The modulation of Amyotrophic Lateral Sclerosis risk by Ataxin-2 intermediate polyglutamine expansions is a specific effect. Neurobiol Dis, 2012. 45(1):356-361.

35. Couthouis J., M.P. Hart, J. Shorter, M. DeJesus-Hernandez, R. Erion, R.E. Oristano, X.A. Liu, D. Ramos, N. Jethava, D. Hosangadi, J. Epstein, A. Chiang, Z. Diaz, T. Nakaya, F. Ibrahim, H.J. Kim, J.A. Solski, K.L. Williams, J. Mojsilovic-Petrovic, C. Ingre, K. Boylan, N. Graff-Radford, D. Dickson, D. Clay-Falcone, L. Elman, L. McCluskey, R. Greene, R.G. Kalb, V.M. Lee, J.Q. Trojanowski, A.C. Ludolph, W. Robberecht, P.M. Andersen, G.A. Nicholson, I.P. Blair, O.D. King, N.M. Bonini, V.M. Van Deerlin, R.

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Rademakers, Z. Mourelatos, A.D. Gitler, A yeast functional screen predicts new candidate ALS disease genes. Proc Natl Acad Sci USA, 2011. 108 (52): 20881-20890. (Feature Article; Featured on the Cover). PMCID: PMC3248518

36. Liu-Yesucevitz L., G. Bassell, A.D. Gitler, A. Hart, E. Klann, J. Richter, S. Warren, B. Wolozin, Local RNA Translation at the Synapses and in Disease. J Neurosci, 2011. 31(45):16086-16093. PMCID: PMC3241995

37. King, O.D.*, A.D. Gitler,* J. Shorter*, The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. Brain Res, 2012. 1462:61-80. *Co-corresponding authors. PMCID: PMC3372647

38. Chesi, A., A. Kilaru, X. Fang, A.A. Cooper, A.D. Gitler, The Role of the Parkinson's Disease Gene PARK9 in Essential Cellular Pathways and the Manganese Homeostasis Network in Yeast. PLoS One, 2012. 7(3): e34178. PMCID: PMC3311584

39. Couthouis, J., M.P. Hart, R. Erion, Z. Diaz, T. Nakaya, F. Ibrahim, H.J. Kim, J. Mojsilovic-Petrovic, D. Clay-Falcone, L. Elman, L. McCluskey, R. Greene, R.G. Kalb, V.M. Lee, J.Q. Trojanowski, G.A. Nicholson, I.P. Blair, O.D. King, N.M. Bonini, V.M. Van Deerlin, Z. Mourelatos, J. Shorter, A.D. Gitler, Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum Mol Genet, 2012. 21(13): 2899-2911. PMCID: PMC3373238

40. Hart, M.P., J. Brettschneider, V.M. Lee, J.Q. Trojanowski, A.D. Gitler, Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions. Acta Neuropathol, 2012. 124(2): 221-230. PMCID: PMC3543833

41. Hart, M.P. and A.D. Gitler, ALS-associated ataxin 2 polyQ expansions enhance stress-induced caspase 3 activation and increase TDP-43 pathological modifications. J Neurosci, 2012. 32(27): 9133-9142. (This Week in the Journal Featured Article). PMCID: PMC3418890

42. Weisberg, S.J., R. Lyakhovetsky, A. Werdiger, A.D. Gitler, Y. Soen, D. Kaganovich, Compartmentalization of SOD1 G93A Aggregates Determines Their Toxicity. Proc Natl Acad Sci USA, 2012. 109(39): 15811-15816. PMCID: PMC3465386

43. Armakola, M.*, M.J. Higgins*, M.D. Figley, S. Barmada, E.A. Scarborough, Z. Diaz, X. Fang, J. Shorter, N.J. Krogan, S. Finkbeiner, R.V. Farese Jr#, A.D. Gitler#, Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nat Genet, 2012. 44(12): 1302-1309. *These authors contributed equally, #Co-corresponding authors. PMCID: PMC3510335

44. Kim, H.J., N.C. Kim, Y. Wang, E.A. Scarborough, J. Moore, Z. Diaz, K.S. Maclea, B. Freibaum, S. Li, A. Molliex, A.P. Kanagaraj, R. Carter, K. Boylan, A.M. Wojtas, R. Rademakers, J.L. Pinkus, S.A. Greenberg, J.Q. Trojanowski, B.J. Traynor, B.N. Smith, S. Topp, A-S. Gkazi, J. Miller, C.E. Shaw, M. Kottlors, J. Kirschner, A. Pestronk, Y.R. Li, A.F. Ford, A.D. Gitler, M. Benatar, O.D. King, V.E. Kimonis, E.D. Ross, C.C. Weihl, J. Shorter, J.P. Taylor, Prion-like domain mutations in hnRNPs cause multisystem proteinopathy and ALS. Nature, 2013. 495(7442): 467-473. PMCID: PMC3756911

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45. Figley, M.D., A.D. Gitler, Yeast genetic screen reveals novel therapeutic strategy for ALS. Rare Diseases, 2013. 1(1): e24420. (Featured on the Cover). PMCID: PMC3933050

46. Li, Y.R.*, O.D. King, J. Shorter*, A.D. Gitler*, Stress granules as crucibles of ALS pathogenesis. J Cell Biol, 2013. 201(3): 367-372. *Co-corresponding authors. PMCID: PMC3639398

47. Chesi, A.*, B.T. Staahl, A. Jovicic, J. Couthouis, M. Fasolino, A.R. Raphael, T. Yamazaki, L. Elias, M. Polak, C. Kelly, K.L. Williams, J.A. Fifita, N.J. Maragakis, G.A. Nicholson, O.D. King, R. Reed, G.R. Crabtree, I.P. Blair, J.D. Glass, A.D. Gitler*, Exome sequencing to identify de novo mutations in sporadic ALS trios. Nat Neurosci, 2013. 16(7): 851-855. *Co-corresponding authors. PMCID: PMC3709464

48. Staahl B.T., J. Tang, W. Wu, A. Sun, A.D. Gitler, A. Yoo, G.R. Crabtree, Kinetic Analysis of npBAF to nBAF Switching Reveals Exchange of SS18 with CREST and Integration with Neural Developmental Pathways. J Neurosci, 2013. 33(25):10348-61. PMCID: PMC3685834

49. Figley, M.D., A. Thomas, A.D. Gitler, Evaluating non-coding nucleotide expansions in amyotrophic lateral sclerosis. Neurobiol Aging, 2014. 35(4):936.e1-4. PMCID: PMC3880650

50. Kim H.J., A.R. Raphael, E.S. LaDow, L. McGurk, R. Weber, J.Q. Trojanowski, V. M.-Y. Lee, S. Finkbeiner, A.D. Gitler, N.M. Bonini, Therapeutic modulation of stress granule-associated eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models. Nat Genet, 2014. 46(2):152-60. PMCID: PMC3934366

51. Couthouis J., A.R. Raphael, C. Siskind, A.R. Findlay, J.D. Buenrostro, W.J. Greenleaf, H. Vogel, J.W. Day, K.M. Flanigan, and A.D. Gitler, Exome Sequencing Identifies a DNAJB6 Mutation in a Family with Dominantly-Inherited Limb-Girdle Muscular Dystrophy, Neuromuscul Disord, 2014. 24(5):431-435. PMCID: PMC4013999

52. Akimoto, C., A.E. Volk, M. van Blitterswijk, M. Van Den Broeck, C.S. Leblond, S. Lumbroso, W. Camu, B. Neitzel, O. Onodera, W. van Rheenen, S. Pinto, M. Weber, B. Smith, M. Proven, K. Talbot, P. Keagle, A. Chesi, A. Ratti, J. van der Zee, H. Alstermark, A. Birve, D. Calini, A. Nordin, D.C. Tradowsky, W. Just, H. Daoud, S. Angerbauer, M. DeJesus-Hernandez, T. Konno, A. Lloyd-Jani, M. de Carvalho, K. Mouzat, J.E. Landers, J.H. Veldink, V. Silani, A.D. Gitler, C.E. Shaw, G.A. Rouleau, L.H. van den Berg, C. Van Broeckhoven, R. Rademakers, P.M. Andersen, C. Kubisch, A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories, J Med Genet, 2014. 51(6):419-424. PMCID: PMC4033024

53. Fares, M.-B., N.A. Bouziad, I. Dikiy, M.M. Kamdem, A. Jovicic, A. Kiely, J.L. Holton, S.-J. Lee, A.D. Gitler, D. Eliezer, and H.A. Lashuel, The Novel Parkinson’s Disease Linked Mutation G51D Attenuates In Vitro Aggregation and Membrane Binding of α-Synuclein, and Enhances its Secretion and Nuclear Localization, Hum Mol Genet, 2014. 23(17):4491-509. PMCID: PMC4119404

54. Raphael, A.R., J. Couthouis, S. Sakamuri, C. Siskind, H. Vogel, J.W. Day, A.D. Gitler, Congenital Muscular Dystrophy and Generalized Epilepsy Caused by GMPPB Mutations, Brain Res, 2014. 1575:66-71. PMCID: PMC4108529

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55. Guo, L., B.I. Giasson, A. Glavis-Bloom, M.D. Brewer, J. Shorter, A.D. Gitler, X. Yang, A cellular system that degrades misfolded proteins through sequential SUMOylation and ubiquitination, Mol Cell, 2014. 55(1):15-33.

56. Figley, M.D., G. Bieri, R.M. Kolaitis, J.P. Taylor, A.D. Gitler, Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics, J Neurosci, 2014. 34(24):8083-8097. PMCID: PMC4051967

57. Couthouis, J., A. Raphael, R. Daneshjou, A.D. Gitler, Targeted exon capture and sequencing in sporadic amyotrophic lateral sclerosis, PLoS Genet, 2014. 10(10):e1004704. PMCID: PMC4191946

58. Dhungel N.*, S. Eleuteri*, L. Li, N.J. Kramer, J.W. Chartron, B. Spencer, K. Kosberg, J.A. Fields, K. Stafa, A. Adame, H. Lashuel, J. Frydman, K. Shen, E. Masliah#, A.D. Gitler#, Parkinson’s disease genes VPS35 and EIF4G1 interact genetically and converge on synuclein, Neuron, 2015. 85: 76-87. *These authors contributed equally, #Co-corresponding authors. PMCID: PMC1183940

59. Cirulli, E.T., B.N. Lasseigne, S. Petrovski, P.C. Sapp, P.A. Dion, C.S. Leblond, J. Couthouis, Y-F. Lu, Q. Wang, B.J. Krueger, Z. Ren, J. Keebler, Y. Han, S.E. Levy, B.E. Boone, J.R. Wimbish, L.L. Waite, A.L. Jones, J.P. Carulli, A.G. Day-Williams, J.F. Staropoli, W.W. Xin, A. Chesi, A.R. Raphael, D. McKenna-Yasek, J. Cady, J.M.B. Vianney de Jong, K.P. Kenna, B.N. Smith, S. Topp, J. Miller, A. Gkazi, FALS Sequencing Consortium, A. Al-Chalabi, L.H. van den Berg, J. Veldink, V. Silani, N. Ticozzi, C.E. Shaw, R.H. Baloh, S. Appel, E. Simpson, C. Lagier-Tourenne, S.M. Pulst, S. Gibson, J.Q. Trojanowski, L. Elman, L. McCluskey, M. Grossman, N.A. Shneider, W.K. Chung, J.M. Ravits, J.D. Glass, K.B. Sims, V.M. Van Deerlin, T. Maniatis, S.D. Hayes, A. Ordureau, S. Swarup, J. Landers, F. Baas, A. S. Allen, R.S. Bedlack, J.W. Harper, A.D. Gitler, G.A. Rouleau, R.H. Brown Jr., M.B. Harms, G.M. Cooper, T. Harris, R.M. Myers, D.B. Goldstein, Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways, Science, 2015. 347(6229): 1436-1441.

60. Jovičić, A., J. Mertens, S. Boeynaems, E. Bogaert, N. Chai, S.B. Yamada, J.W. Paul, III, S. Sun, J.R. Herdy, G. Bieri, N.J. Kramer, F.H. Gage, Ludo Van Den Bosch, W. Robberecht, A.D. Gitler, Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS, Nat Neurosci, 2015. 18(9): 1226-1229.

61. Coyne, A.N., S.B. Yamada, B.B. Siddegowda, P.S Estes, B.L. Zaepfel, J.S. Johannesmeyer, D.B Lockwood, L.T. Pham, M.P Hart, J.A. Cassel, B. Freibaum, A.V. Boehringer, J.P. Taylor, A.B. Reitz, A.D. Gitler, D.C. Zarnescu, Fragile X protein is neuroprotective by remodeling TDP-43 containing RNA granules and restoring the translation of specific mRNA targets, Hum Mol Genet, 2015. 24(24): 6886-6898.

62. Margulis, N.G., J.D. Wilson, C.M. Bentivoglio, N. Dhungel, A.D. Gitler, C. Barlowe, Analysis of COPII vesicles indicates a role for the Emp47-Ssp120 complex in transport of cell surface glycoproteins, Traffic, 2016. 17(3):191-210.

63. Brahic, M., L. Bousset, G. Bieri, R. Melki, A.D. Gitler, Axonal Transport and Secretion of Fibrillar Forms of -synuclein, Aß42 Peptide and HTTExon 1, Acta Neuropathol, 2016. Jan 28.

64. Boeynaems, S., E. Bogaert, E. Michiels, I. Gijselinck, A. Sieben, A. Jovičić, G. De Baets, W. Scheveneels, J. Steyaert, I. Cuijt, K.J. Verstrepen, P. Callaerts, F. Rousseau, J. Schymkowitz, M. Cruts, C. Van Broeckhoven, P. Van Damme, A.D. Gitler, W.

Page 8 of 26

Robberecht, L. Van Den Bosch, Drosophila screen connects nuclear transport defects to DPR pathology in c9ALS/FTD, Sci Rep, 2016. 6:20877.

65. Gitler, A.D. and H. Tsuiji, There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS, Brain Res, 2016. April 5.

66. Williams, K.L., S. Topp, S. Yang, B. Smith, J.A. Fifita, S.T. Warraich, K.Y. Zhang, N. Farrawell, C. Vance, X. Hu, A. Chesi, C.S. Leblond, V. Sundaramoorthy, C. Dobson-Stone, A. Lee, S.L. Rayner, M.P. Molloy, M. van Blitterswijk, D.W. Dickson, R.C. Petersen, N.R. Graff-Radford, B.F. Boeve, M.E. Murray, C. Pottier, E. Don, C. Winnick, E.P. McCann, A. Hogan, H. Daoud, A. Levert, P.A. Dion, J. Mitsui, H. Ishiura, Y. Takahashi, J. Goto, J. Kost, C. Gellera, A. Soragia Gkazi, J. Miller, J. Stockton, W.S. Brooks, K. Boundy, M. Polak, J. Luis Muñoz-Blanco, J. Esteban-Pérez, A. Rábano, O. Hardiman, K.E. Morrison, N. Ticozzi, V. Silani, J. de Belleroche, J.D. Glass, J.B.J. Kwok, G.J. Guillemin, R.S. Chung, S. Tsuji, R.H. Brown Jr, A. García-Redondo, R. Rademakers, J.E. Landers, A.D. Gitler, G.A Rouleau, N.J. Cole, J.J. Yerbury, J.D. Atkin, C.E. Shaw, G.A. Nicholson, and I.P. Blair, CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia, Nat Comm, 2016. April 15.

67. Jovičić, A., J.W. Paul, A.D. Gitler, Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia, J Neurochem, 2016. April 17.

68. Lee, S., Y. Shang, S.A. Redmond, A. Urisman, A.A. Tang, K.H. Li, A.L. Burlingame, R.A. Pak, A. Jovičić, Aaron D. Gitler, J. Wang, N.S. Gray, W.W. Seeley, T. Siddique, E.H. Bigio, V. M.-Y. Lee, J.Q. Trojanowski, J.R. Chan, and E.J. Huang, Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis, Neuron, 2016. June 16.

69. Dikiy, I., B. Fauvet, A. Jovičić, A. Mahul-Mellier, C. Desobry, F. El-Turk, A.D. Gitler, H. Lashuel, D. Eliezer, Semisynthetic and in vitro phosphorylation of alpha-synuclein at Y39 promotes functional partly-helical membrane-bound states resembling those induced by PD mutations, ACS Chem Biol, 2016. June 29.

70. Kramer, N.J.*, Y. Carlomagno*, Y. Zhang*, S. Almeida, C.N. Cook, T.F. Gendron, M. Prudencio, M. Van Blitterswijk, V. Belzil, J. Couthouis, J.W. Paul III, L.D. Goodman, L. Daughrity, J. Chew, A. Garrett, L. Pregent, K. Jansen-West, L.J. Tabassian, R. Rademakers, K. Boylan, N.R. Graff-Radford, K.A. Josephs, J.E. Parisi, D.S. Knopman, R.C. Petersen, B.F. Boeve, N. Deng, Y. Feng, T.H. Cheng, D.W. Dickson, S.N. Cohen, N.M. Bonini, C.D. Link, F.B. Gao, L. Petrucelli#, A.D. Gitler#, Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts, Science, 2016. 353(6300):708-712. *These authors contributed equally, #Co-corresponding authors.

71. Abeliovich, A. and A.D. Gitler, Trafficking defects bridge Parkinson’s disease pathology and genetics, Nature, 2016. 539:207-216.

72. Sproviero, W., A. Shatunov, D. Stahl, M. Shoai, W. van Rheenen, A.R. Jones, S. Al-Sarraj, P.M. Andersen, N.M. Bonini, F.L. Conforti, P. Van Damme, H. Daoud, M. Del Mar Amador, I. Fogh, M. Forzan, B. Gaastra, C. Gellera, A.D. Gitler, J. Hardy, P. Fratta, V. La Bella, I. Le Ber, T. Van Langenhove, S. Lattante, Y.-C. Lee, A. Malaspina, V. Meininger, S. Millecamps, R. Orrell, R. Rademakers, W. Robberecht, G. Rouleau, O.A. Ross, F. Salachas, K. Sidle, B.N. Smith, B.-W. Soong, G. Soraru, G. Stevanin, E. Kabashi, C. Troakes, C. van Broeckhoven, J.H. Veldink, L. van den Berg, C.E. Shaw,

Page 9 of 26

J.F. Powell, A. Al-Chalabi, ATXN2 Trinucleotide Repeat Length Correlates with Risk of ALS, Neurobiol Aging, 2016, doi: 10.1016/j.neurobiolaging.2016.11.010.

73. Jovičić, A. and A.D. Gitler, Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes, PLoS One, 2017, 12(2):e0171418.

74. Becker, L.A., B. Huang, G. Bieri, R. Ma, D.A. Knowles, P. Jafar-Nejad, J. Messing, H.J. Kim, A. Soriano, G. Auburger, S.M. Pulst, J.P. Taylor, F. Rigo, and A.D. Gitler, Therapeutic reduction of ataxin 2 extends lifespan reduces pathology in TDP-43 mice, Nature, 2017. In press.

75. Bieri, G., A.D. Gitler, M. Brahic, Internalization, axonal transport and release of fibrillar forms of alpha-synuclein, Neurobiol Dis, 2017. In press.

Non-Peer-reviewed Articles (19 total):

1. Gitler, A.D., C.B. Brown, L. Kochilas, J. Li, J.A. Epstein, Neural crest migration and mouse models of congenital heart disease. Cold Spring Harb Symp Quant Biol, 2002. 67: p. 57-62.

2. Gitler, A.D. and J.A. Epstein, Regulating heart development: the role of Nf1. Cell Cycle, 2003. 2(2): p. 96-8. (Featured on the cover)

3. Gitler, A.D.* and J. Shorter*, Prime Time for Synuclein. J Neurosci, 2007, 27:2433-2434. * Co-corresponding authors

4. Gitler, A.D., Disease models and mechanisms in the classroom. Dis Model Mech, 2009. 2(3-4):103-106. (Featured in a Podcast). PMCID: PMC2650211

5. Bonini N.M., A.D. Gitler, Model organisms reveal insight into human neurodegenerative disease: Ataxin-2 intermediate length polyglutamine expansions are a risk factor for ALS. J Mol Neurosci, June 2011. PMCID: PMC3207127

6. Gitler A.D., Another Reason to Exercise., 2011. 334(6056):606-607.

7. Gitler, A.D.* and R. Lehmann*, Modeling Human Disease. Science, 2012. 337(6092):269. *Co-corresponding authors.

8. Gitler, A.D., TDP-43 and FUS/TLS provide a target-rich haul in ALS. Nat Neurosci, 2012. 15(11): 1467-1469.

9. Chuang, R.S.* and A.D. Gitler*, Parallel PARKing: Parkinson’s genes function in common pathway. Neuron, 2013. 77(3): 377-379. *Co-corresponding authors.

10. Aguzzi, A.* and A.D. Gitler*, A template for new drugs against Alzheimer’s disease. Cell, 2013. 154(6). 1182-1184. *Co-corresponding authors.

11. Jovičić, A. and A.D. Gitler, TDP-43 in ALS: Stay on target… Almost there. Neuron, 2014. 81(3):463-5.

12. Gitler, A.D., Yeast cells are rising to the occasion for ALS research. Research ALS Today, 2014. Spring 2014.

13. Paul, J.W. III and A.D. Gitler, Clogging information flow in ALS. Science, 2014. 345(6201): 1118-1119.

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14. Becker, L.A. and A.D. Gitler, RNA and protein granules: It’s all coming together. eLife, 2015. 4:e09853.

15. Figley, M.D. and A.D. Gitler, Neurodegeneration: A Leg Up on TDP-43. Curr Biol, 2015. 25(16): R728-R731.

16. Kramer, N.J. and A.D. Gitler, Regrowing axons with alternative splicing. eLife, 2016. July 15.

17. Shorter, J.S. and A.D. Gitler, Susan Lee Lindquist (1949-2016). Nature, 2016. Dec 1.

18. Kramer, N.J. and A.D. Gitler, Raise the roof: boosting the efficacy of a spinal muscular atrophy therapy. Neuron, 2017. 93:3-5.

19. Gitler A.D. and D.F. Jarosz, Old moms say no Sir. Science, 2017. In press.

G. INVITED PRESENTATIONS

2005: Catecholamines Gordon Conference. Andover, NH2006: Keystone Symposium: Protein misfolding disorders. Breckenridge, CO2006: Protein Society Annual Symposium. San Diego, CA2006: Museum of Science Frontiers of Health Science Seminar Series. Cambridge, MA

(Featured Speaker)2006: Cold Spring Harbor Meeting, Neurodegenerative Diseases: Biology and Therapeutics.

Cold Spring Harbor, NY2007: Tsinghua University Department of Biological Sciences and Biotechnology. Beijing,

China2007: GlaxoSmithKline R&D China. Shanghai, China2007: Institute of Health Sciences, Shanghai Jiao Tong University Medical School. Shanghai,

China2008: Wistar Institute. Philadelphia, PA2008: Swarthmore College, Swarthmore, PA2008: University of Pennsylvania Biomedical Graduate Students Association Research

Symposium. Philadelphia, PA (Keynote Speaker)2008: Molecular and Cellular Neurobiology Gordon Conference. Hong Kong, China2008: Johns Hopkins University School of Medicine, Department of Cell Biology. Baltimore,

MD2008: Cold Spring Harbor Meeting, Neurodegenerative Diseases: Biology and Therapeutics.

Cold Spring Harbor, NY2009: Johns Hopkins University School of Medicine, Robert Packard Center for ALS Research.

Baltimore, MD2009: Haverford College. Haverford, PA2009: Penn State University, Department of Biochemistry and Molecular Biology. University

Park, PA2009: LSRF East Coast Alumni Symposium, Whitehead Institute for Biomedical Research.

Cambridge, MA2009: Center of Excellence in Environmental Toxicology, the University of Pennsylvania

School of Medicine, Philadelphia, PA

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2009: Center for Molecular Studies in Digestive and Liver Diseases, the University of Pennsylvania School of Medicine, Philadelphia, PA

2009: Yale University School of Medicine, Program in Cellular Neuroscience, Neurodegeneration and Repair, New Haven, CT

2009: University of Chicago, Committee on Molecular Medicine, Chicago, IL2010: Thomas Jefferson University, Distinguished Lecture Series, Department of Pathology,

Anatomy and Cell Biology, Philadelphia, PA2010: Ringberg Symposium on Neurodegeneration in Zebrafish, Munich, Germany2010: Department of Neurology, Goethe University, Frankfurt am Main, Germany2010: Haverford College, Department of Biology, Haverford, PA.2010: Society for Neuroscience Satellite Workshop: Advances in Disease Modeling for ALS

and FTD. San Diego, CA (Session Chair)2010: Cold Spring Harbor Meeting, Neurodegenerative Diseases: Biology and Therapeutics.

Cold Spring Harbor, NY2010: 21st International Symposium on ALS/MND, Orlando, FL2011: University of California Berkeley, Department of Nutritional Science & Toxicology,

Berkeley, CA2011: University of California San Francisco, Biomedical Sciences Seminar Series, San

Francisco, CA2011: Genentech, South San Francisco, CA2011: Adler Symposium on “Cell autonomous and non-cell autonomous basis of protein

misfolding in neurodegeneration: Lessons from normal biology, Alzheimer’s disease and frontotemporal dementia/motor neuron disease”, The Salk Institute, San Diego, CA

2011: Stanford University School of Medicine, Department of Genetics, Palo Alto, CA2011: Webinar on stress granules in neurodegeneration, Alzforum. 2011: Keystone Symposium on Neurodegenerative Diseases:  The Molecular and Cellular Basis

for Neurodegeneration. Taos, NM2011: Robert Packard Center for ALS Research Annual Meeting. Baltimore, MD (Session

Chair)2011: Biogen Idec, Cambridge, MA2011: Clinical Neurosciences Training Seminar, University of Pennsylvania, Philadelphia, PA2011: Columbia University, Department of Genetics and Development, New York, NY2011: Defining New Frontiers in Neurodegeneration Workshop, the University of

Massachusetts Neurotherapeutics Institute, Boston, MA2011: Guest instructor of course on protein misfolding and aggregation in the brain, and its

consequences, Neuroscience School of Advanced Studies, Siena, Italy 2011: GlaxoSmithKline R&D China. Shanghai, China2011: Cold Spring Harbor Meeting, Protein Homeostasis in Health & Disease. Suzhou, China

(Session Chair)2011: University of Toronto, Department of Biochemistry, Toronto, Ontario, Canada2011: University of Arizona, Department of Molecular and Cellular Biology, Tucson, AZ2011: Temple University, Department of Biochemistry, Philadelphia, PA2011: 6th Brain Research Conference, “RNA Binding Proteins in Neurological Disease”,

Washington, D.C.2011: Society for Neuroscience Annual Meeting, “New RNA Binding Proteins in ALS”,

Washington, D.C.

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2011: Drexel University, Department of Biology, Philadelphia, PA2011: 22nd International Symposium on ALS/MND, Sydney, Australia (Paulo Gontijo Young

Investigator Award lecture)2012: American Society for Neurochemistry Annual Meeting, Baltimore, MD2012: Stanford University, Department of Neurology Movement Disorders Conference,

Stanford, CA2012: University of California San Francisco, Memory and Aging Center Grand Rounds, San

Francisco, CA2012: Neurobiology of Brain Disorders Gordon Conference, Easton, MA2012: The 8th International Conference on Frontotemporal Dementias, Manchester, United

Kingdom2012: Boston University, Department of Biochemistry, Boston, MA2012: Janelia Conference: Molecular Mechanisms of Axon Degeneration, Ashburn, VA

(Session Chair) 2012: FTD/ALS meeting, Shenzhen, China (Plenary Speaker)2012: University of Washington, Department of Pharmacology, Seattle, WA2012: Cold Spring Harbor Meeting, Neurodegenerative Diseases: Biology and Therapeutics.

Cold Spring Harbor, NY2013: Dartmouth University, Department of Biochemistry, Hanover, NH2013: University of Miami, Department of Pharmacology, Miami, FL2013: Stanford University, Department of Neurology Grand Rounds, Stanford, CA2013: University of Zurich, Zurich, Switzerland2013: Novartis, Basel, Switzerland2013: Meeting of the German Society of Human Genetics, Dresden, Germany (Plenary

Speaker)2013: Stowers Institute for Medical Research, Kansas City, MO2013: International Society for Neurochemistry Biannual Meeting, Cancun, Mexico (Young

Investigator Award lecture)2013: Muscular Dystrophy Association National Scientific Meeting, Washington, D.C.

(Plenary Speaker)2013: Mayo Clinic, Department of Neuroscience, Jacksonville, FL2013: ALS Canada Research Forum, Toronto, Ontario, Canada (Plenary Speaker)2013: The 5th Annual Jungers Center Symposium, "Neurodegeneration: new themes, new

approaches". The Vollum Institute at Oregon Health and Science University, Portland, OR (Plenary Speaker)

2013: Prion Review Meeting, University of California San Francisco, San Francisco, CA2013: Team Gleason ALS Summit, New Orleans, LA2013: Novartis Annual Retreat, Cape Cod, MA (Plenary Speaker)2013: Stanford University, Department of Biology, Stanford, CA2013: Stanford University, Frontiers in Cardiovascular Science, Stanford, CA2013: Australian Society of Biochemistry and Molecular Biology ComBio 2013 Meeting, Perth,

Australia (Plenary Speaker)2013: ALS TDI Annual Leadership Summit, Cambridge, MA (Plenary Speaker)2013: Genentech, South San Francisco, CA2013: 8th Brain Research Conference, “RNA Metabolism in Neurological Disease”, San Diego,

CA (Plenary Speaker)

Page 13 of 26

2013: Weill Cornell Medical College, Department of Biochemistry, New York, NY2013: Colorado State University Prion Research Center Symposium, Fort Collins, CO (Plenary

Speaker)2013: University of Chicago, Department of Neurobiology, Chicago, IL2013: University of Michigan, Department of Neurology, Protein Folding Disorder Research

Symposium, Ann Arbor, MI (Keynote Speaker)2013: Harvard Medical School and Massachusetts General Hospital, Department of Neurology,

Boston, MA2014: California ALS Research Summit, Fresno, CA (Keynote Speaker)2014: Adler Symposium on "CNS Innate Immunity, Seeding/Spreading, Prion domains, and

RNA Binding proteins in Neurodegenerative Diseases". The Salk Institute, San Diego, CA (Plenary Speaker)

2014: Stanford University, Department of Bioengineering, Stanford, CA2014: University of California Santa Cruz, Department of Molecular, Cellular and

Developmental Biology, Santa Cruz, CA2014: Gladstone Institute of Neurological Disease, San Francisco, CA2014: University of Chicago, Department of Neurology, Translational Research Symposium,

Chicago, IL (Plenary Speaker)2014: The 12th annual meeting of the European Network for the Cure of Amyotrophic Lateral

Sclerosis (ENCALS), Leuven, Belgium (Plenary Speaker)2014: RNA Metabolism: changing paradigms in neurodegeneration, ICGEB, Trieste, Italy

(Keynote Speaker)2014: Cell Biology of the Neuron Gordon Conference, Waterville Valley Resort, NH 2014: Molecular and Cellular Neurobiology Gordon Conference. Hong Kong, China2014: University of Nevada Reno Graduate Student Symposium (Keynote Speaker)2014: Riken Brain Science Institute, Tokyo, Japan2014: Japan Neuroscience Society Annual Meeting, Tokyo, Japan (Plenary Speaker)2014: Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy

of Sciences, Shanghai, China2014: Zhejiang University, Hangzhou, China2014: Cytokinetics, Inc., South San Francisco, CA2014: Gerontological Society of America, Washington, D.C. (Plenary Speaker)2014: University of British Columbia, Brain Research Centre, Vancouver, BC, Canada2014: Cold Spring Harbor Meeting, Neurodegenerative Diseases: Biology and Therapeutics.

Cold Spring Harbor, NY (Plenary Speaker)2015: Ohio State University, Center for RNA Biology, Columbus, OH2015: Nationwide Center for Muscle Health and Neuromuscular Disorders, Columbus, OH2015: Baylor College of Medicine, Department of Molecular & Human Genetics, Houston, TX2015: 8th International Meeting on Unstable Microsatellites and Human Disease, Guanacaste,

Costa Rica (Plenary Speaker)2015: American Academy of Neurology, Breakthroughs in Neurology: Translating Today’s

Discoveries into Tomorrow’s Clinics, Phoenix, AZ (Plenary Speaker)2015: Oregon Health & Science University, Department of Molecular and Medical Genetics,

Portland, OR2015: American Society for Neurochemistry Symposium: RNA Toxicity in Neurodegeneration.

Atlanta, GA (Plenary Speaker)

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2015: Brandeis University, Department of Biology, Waltham, MA2015: University of Massachusetts Medical Center, Department of Neurology, Worcester, MA2015: Boston University, Department of Pharmacology, Boston, MA2015: University of Maine, Department of Molecular and Biomedical Sciences, Orono, ME2015: EMBO Workshop: Macromolecular assemblies at the crossroads of cell stress and

function, Jerusalem, Israel (Plenary Speaker)2015: University of Ulm, Department of Neurology, Ulm, Germany2015: Parkinson’s Disease Gordon Conference, New London, NH (Plenary Speaker)2015: Denali Therapeutics, South San Francisco, CA2015: Fidelity Biosciences Research Initiative, Workshop on Alzheimer’s disease and related

disorders, Cape Cod, MA (Plenary Speaker)2015: Thomas Jefferson University, Distinguished Lecture Series, Department of Pathology,

Anatomy and Cell Biology, Philadelphia, PA2015: University of Pennsylvania Biomedical Graduate Studies 30th Anniversary. Philadelphia,

PA (Keynote Speaker)2015: 10th Brain Research Conference, “RNA Metabolism in Neurological Disease”, Chicago,

IL (Plenary Speaker)2016: Institute of Molecular Medicine at UT Health Science Center, Houston, TX2016: California ALS Research Summit, San Diego, CA (Plenary Speaker)2016: Neuroscience Seminar Series, Penn State University, University Park, PA2016: Biological Chemistry Seminar Series, University of Pennsylvania, Philadelphia, PA2016: Department of Biological Sciences & Biotechnology, Tsinghua University, Beijing,

China2016: Regeneron Pharmaceuticals, Tarrytown, NY2016: Neurodegeneration Symposium and Workshop, Jan and Dan Duncan Neurological

Research Institute, Houston, TX2016: Department of Pathology, Columbia University, New York, NY2016: Department of Neuroscience, Oregon Health & Science University, Portland, OR2016: Department of Cell & Molecular Biology, St. Jude Children’s Research Hospital,

Memphis, TN 2016: Molecular and Cellular Neurobiology Gordon Research Conference, Hong Kong, China

(Plenary Speaker)2016: Max Planck Institute of Cell Biology and Genetics, Dresden, Germany2016: Deutsches Zentrum für Neurodegenerative Erkankungen (DZNE), Munich, Germany2016: Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland2016: Institute of Science and Technology, Vienna, Austria2016: Munich Cluster for Systems Neurology, Munich, Germany2016: Max Planck Institute of Biochemistry, Munich, Germany2016: Neurobiology of Brain Disorders Gordon Research Conference, Girona, Spain2016: Genentech, South San Francisco, CA2016: 10th International Conference on Frontotemporal Dementias, Munich, Germany (Plenary

Speaker)2016: Cold Spring Harbor Meeting, Translational Control, Cold Spring Harbor, NY (Keynote

Speaker) 2016: Grand Challenges in Parkinson’s Disease, Van Andel Research Institute, Grand Rapids,

MI (Plenary Speaker)

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2016: 11th Brain Research Conference, “RNA Metabolism in Neurological Disease”, San Diego, CA (Plenary Speaker)

2016: Zhejiang University, Hangzhou, China2016: Neuroscience Seminar Series, Weill Cornell Medical College, New York, NY2017: California ALS Research Summit, Los Angeles, CA2017: Amgen, Cambridge, MA2017: Picower Institute for Learning and Memory, Massachusetts Institute of Technology,

Cambridge, MA2017: Lisa Krivickas Lecture, Harvard Medical School and Massachusetts General Hospital,

Neurology Grand Rounds, Boston, MA2017: Department of Molecular Biology, University of Texas Southwestern, Dallas, TX2017: Department of Biophysics, Johns Hopkins University, Baltimore, MD2017: Department of Biochemistry, Emory University, Atlanta, GA2017: Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX2017: Department of Neurology, The University of Alabama at Birmingham, Birmingham, AL2017: Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA2017: Alzheimer’s Association International Conference, London, England (Plenary Speaker)2017: Amyotrophic Lateral Sclerosis & Related Motor Neuron Disease Gordon Research

Conference, West Dover, VT (Plenary Speaker)2017: Janelia conference on Cell Biology of Neurons and Circuits, Ashburn, VA 2018: Advances in Neurodegenerative Diseases Research and Therapy Keystone Symposium,

Keystone, CO (Plenary Speaker)

H. EDITORIAL SERVICES

Journal Referee:

NatureScienceCellNeuronMolecular CellNature MedicineNature NeuroscienceScience Translational MedicinePNASeLifeCurrent BiologyThe Journal of Clinical InvestigationThe Journal of NeurosciencePLoS BiologyPLoS GeneticsPLoS OneHuman Molecular GeneticsAnnals of NeurologyActa Neuropathologica

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NeurologyScientific ReportsDevelopmental BiologyDevelopmental DynamicsNeuroscience LettersBiotechnology and BioengineeringFree Radical Biology & MedicineExperimental NeurologyNeurobiology of AgingYeastTrends in Biochemical SciencesNeurogeneticsAquatic ToxicologyLife SciencesMethodsFEBS LettersParkinson’s DiseaseHuman GeneticsJournal of Visualized ExperimentsDisease Models and MechanismsJournal of Molecular BiologyMovement Disorders

I. GRANTS

Current Research Support:

1R35NS097263 12/01/16-11/30/24NIH R35 NINDS Outstanding Investigator AwardInnovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative DiseaseThis award consolidates my previous NINDS funding and extends the time frame for 8 years. The major goals of the project are to use yeast cells, human CRISPR screens, and mouse models to define mechanisms of neurodegenerative diseases, focusing on ALS and Parkinson’s disease.

Target ALS 5/01/15-4/30/17 Validating ataxin 2 as a therapeutic target in ALSThis is a collaborative consortium of four laboratories aimed at developing and testing therapeutic strategies to lower ataxin 2 in ALS. I am the project leader of this consortium.

Target ALS 5/01/15-4/30/17Exploiting yeast to uncover small molecule drugs for ALS caused by aberrant TDP-43 and FUS proteostasisThis is a collaborative consortium of two laboratories aimed at using yeast cells and small molecule screens to discover chemical compounds that ameliorate FUS or TDP-43 toxicity.

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Muscular Dystrophy Association 05/01/14-04/30/17 Defining a novel role of profilin 1 in ALS pathogenesisThe major goals of this project are to use yeast and mammalian cell assays to characterize a novel role for the ALS protein profilin 1 in stress granules.

Completed Research Support:

C000026971 07/01/07-06/30/08PA Dept. of Community & Economic DevelopmentKeystone Innovation Starter KitYeast High-throughput ScreeningThe major goals of this project are to build high-throughput yeast screening infrastructure

Pilot Grant 07/01/07-06/30/08Alzheimer’s Disease Core Center (Penn)Using zebrafish to study synuclein normal function and role in pathologyThe major goals of this project are use zebrafish to study the Parkinson’s disease protein alpha-synuclein

Pilot Grant 07/01/07-06/30/08Institute on Aging (Penn)A yeast TDP-43 proteinopathy modelThe major goals of this project are to create a yeast TDP-43 proteinopathy model

Fellow Award 07/01/07-06/30/08McCabe Fund Fellow Award (Penn)Exploring the function of the Parkinson’s disease gene PARK9/ATP13A2The major goals of this project are to study the yeast homolog of the Parkinson’s disease protein ATP13A2/PARK9

Pilot Grant 02/01/08-01/31/09Institute for Regenerative Medicine (Penn)Zebrafish as a model for neuro-regenerative medicineThe major goals of this project are to develop transgenic zebrafish to visualize neurodegeneration

Postdoctoral Fellowship (Zhihui Sun) 09/01/08-08/31/09American Parkinson’s Disease Association

Investigating synuclein gene function in zebrafishThe major goals of this project are to perform functional studies of three zebrafish synuclein genes that we recently cloned.

Robert Packard Center for ALS Research 07/01/09-06/30/10

Novel yeast and zebrafish models to explore the role of FUS/TLS in ALS

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This is collaborative grant with Dr. Michael Granato. The major goals of this project are to use yeast and zebrafish to study the ALS gene FUS/TLS.

NF080053 09/01/08-08/31/11US Department of Defense New Investigator AwardExploring the function of neurofibromin in a yeast model of NF1The major goals of this project are to 1) functionally characterize hits from yeast genetic screens 2) validate hits from yeast screens in Drosophila NF1 models

Pilot Grant (co-PI w/ Dr. Vivianna Van Deerlin) 07/01/10-06/30/11

Institute on Aging (Penn)Combining Yeast and Human Genetics to Discover Novel ALS Disease GenesThe major goals of this project are to sequence human genes identified in a yeast functional screen for mutations in ALS patients

N/A 07/01/08-06/30/12Pew Scholars ProgramExploring the cellular and genetic mechanisms of neurodegenerationThe major goals of this project are to use yeast cells to investigate cellular mechanisms underpinning Parkinson’s disease and ALS

N/A 07/01/09-06/30/12Rita Allen FoundationExploring the function of the tumor suppressor neurofibromin in a yeast model of NF1The major goals of this project are perform a high-throughput yeast screen to identify genetic modifiers of ira1 and ira2 phenotypes

Robert Packard Center for ALS Research 1/01/12-12/31/12 Molecular Determinants of FUS aggregation and toxicityThis is collaborative grant with Dr. James Shorter. The major goals of this project are to use yeast pure protein biochemistry to study the ALS disease protein FUS/TLS.

1DP2OD004417-01 09/30/08-06/30/13NIH Director’s New Innovator AwardExploring the cellular and genetic mechanisms of neurodegenerationThe major goals of this project are to use yeast cells to investigate cellular mechanisms underpinning Parkinson’s disease

BiogenIdec 3/01/12-5/29/14ALS Genome Sequencing Consortium with Biogen IdecThis is a collaborative project with Duke University, University Massachusetts Medical School, and BiogenIdec, to sequence and analyze ALS patient exomes and genomes to define new contributors to ALS.

1R01NS093865 08/01/15-07/31/20

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NIH R01Defining the mechanisms of dipeptide repeat protein toxicity in C9orf72 ALS/FTDThe major goals of this project are to use yeast cells, patient cell lines, and animal models to investigate cellular mechanisms underpinning C9orf72 dipeptide repeat protein toxicity in ALS and FTD

1R01NS065317 04/01/14-03/31/19 NIH R01Molecular basis of TDP-43 proteinopathies: disease models and mechanisms The major goals of this project are to use yeast cells and animal models to investigate cellular mechanisms underpinning TDP-43 aggregation and toxicity in ALS

1R01NS073660 12/01/11-11/30/16NIH R01Ataxin-2 as a genetic risk factor for ALS: New insights into neurodegeneration (Co-PI with Nancy Bonini)The major goals of this project are to define the mechanisms by which polyQ expansions in ataxin 2 contribute to ALS.

Novartis Institutes for Biomedical Research 10/18/13 – 09/30/16Alpha-synuclein pathological spread in Parkinson Disease: identifying targets and defining cellular mechanismsThis is an industry-sponsored project aimed at defining the mechanisms by which pathological aggregates of the Parkinson disease protein alpha-synuclein spread from neuron to neuron in cell culture and in mouse brain.

Robert Packard Center for ALS Research 09/01/13-09/30/15 Genetic and biochemical approaches to define mechanisms of repeat-associated non-ATG (RAN) translation products in C9orf72-related ALSThis is collaborative grant with Dr. James Shorter. The major goals of this project are to use yeast and biochemical assays to study aggregation-prone dipeptides in C9orf72-ALS.

Target ALS 5/01/13-4/30/16 Unraveling mechanisms in RNA-binding protein-mediated ALS This is a collaborative consortium of six laboratories aimed at defining the mechanisms by which aggregation-prone RNA-binding proteins contribute to ALS and to define novel targets for therapeutic intervention. I am the project leader of this consortium.

J. TEACHING AND ACADEMIC SERVICE

Academic Committees:

2007-present Preliminary Examination Committees

University of PennsylvaniaKristen Malkus (H. Ischiropoulos), Neuroscience

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Mary Gantz (X. Yang), PharmacologyArun Padmanabhan (J. Epstein), Cell and Molecular BiologyShin-Yi Shieh (N. Bonini), BiologySelçuk Tanik (V. Lee), BiologyMimi Cushman (J. Shorter) [Committee Chair], NeuroscienceEdward Ballister (S. Berger), Biochemistry and Molecular BiophysicsArmen Moughamian (E. Holzbaur) [Committee Chair], NeuroscienceMorgan DeSantis (J. Shorter), Biochemistry and Molecular BiophysicsViktoriya Syrovatkina (P. Tran), Cell and Molecular BiologyLauren Stutzbach (G. Schellenberg) [Committee Chair], NeuroscienceRachel Monyak (T. Jongens), Cell and Molecular Biology

Stanford UniversityJessica Tsai (T. Clandinin), Stanford NeuroscienceIvan Millan (Y. Yang), Stanford NeuroscienceArielle Yablonovitch (J.B. Li), BiophysicsAlicia Shiu (T. Wyss-Coray), NeuroscienceSiming Zhang (A. Urban), GeneticsKimberly Tsui (M. Bassik), GeneticsKevin Guttenplan (B. Barres) [Committee Chair], NeuroscienceAshley Gonzalez (X. Wang), Neuroscience Theo Susanto (M. Barna), Genetics

2007-present Thesis Committees

University of PennsylvaniaJasmine Smith (B. Johnson), Cell and Molecular BiologyTishina Okegbe (S. DiNardo), Cell and Molecular BiologyShin-Yi Shieh (N. Bonini) [Committee Chair], BiologySelçuk Tanik (V. Lee), BiologyArun Padmanabhan (J. Epstein), Cell and Molecular BiologyKristen Malkus (H. Ischiropoulos), NeuroscienceLili Guo (X. Yang), Cell and Molecular BiologyMimi Cushman (J. Shorter), NeuroscienceElizabeth Sweeny (J. Shorter), Biochemistry and Molecular BiophysicsElizabeth Morton (T. Lamitina), Cell and Molecular BiologyOlga Davydenko (M. Lampson), BiologyAzi Kia (P. Pasinelli), Department of Neuroscience, Thomas Jefferson UniversityJessica Bryant (S. Berger), Cell and Molecular Biology

Stanford UniversityJessica Tsai (T. Clandinin), NeuroscienceArielle Yablonovitch (J.B. Li), BiophysicsMara Damian (M. Porteus), BiologyErik Miller (G. Crabtree), GeneticsLaura Eads (E. Miranda)[Committee Chair], Civil and Environmental Engineering

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Alicia Shiu (T. Wyss-Coray), NeuroscienceThomas Ward (A. Urban), GeneticsAnne Sapiro (J.B. Li), GeneticsSteven Sloan (B. Barres), NeuroscienceCaitlin O’Brien (T. Wyss-Coray)[Committee Chair], NeuroscienceLivia Zarnescu (D. Camarillo), BioengineeringMara Pavel-Dinu (M. Porteus), BiologyMichael Haney (M. Bassik), GeneticsGerald Tiu (M. Barna), GeneticsMazen Asaad (J. Lee), Molecular and Cellular PhysiologyZhongnan Fang (J. Lee)[Committee Chair], Electrical EngineeringJanet Song (D. Kingsley), GeneticsSiming Zhang (A. Urban), GeneticsKimberly Tsui (M. Bassik), GeneticsMike John Betley (T. Wyss-Coray) [Committee Chair], NeuroscienceKoning Shen (J. Frydman) [Committee Chair], BiologyRebecca Marton (S. Pasca), Stem Cell BiologyKevin Guttenplan (B. Barres), Neuroscience

Other Committees

University of Pennsylvania2007-2008 Neuroscience Graduate Group Faculty Research Talks (Fall 2007, Fall 2008, Fall

2009)2007-2009 Neuroscience Graduate Group Lab Rotation Talks (Fall 2007, Spring, Summer 2008,

Spring, Summer 2009)2008-2010 Cell and Developmental Biology Seminar Series Committee2010 BGS Responsible Conduct in Research (RCR) workshop facilitator2011 Cell and Developmental Biology Faculty Search Committee

Stanford University2012-2015 Stanford Neurosciences Seminar Series Committee, Chair2012 Stanford Genetics Department Annual Retreat Planning Committee2012- Stanford Neuroscience Graduate Program First Year Graduate Student Advisor2012-2013 Stanford Genetics Faculty Search Committee2013- Stanford Neuroscience Graduate Program Steering Committee2013- Stanford Genetics Graduate Program First Year Graduate Student Advisor2013- Stanford Genetics Women at Stanford2014 Stanford MSTP Admissions Committee2014- Stanford Postdoc Wellness Committee2015 Andrea Hanson-Kahn’s Clinical Asst. Professor Reappointment Committee, Chair2015-2016 Stanford Neurology and Neurological Sciences Faculty Search Committee2015 Stanford Medicine Genetics & Genomics Biobanking Faculty Search Committee2015 Stanford Medicine Behavioral Neurology Faculty Search Committee2015 Stanford Biosciences Grant Writing Academy Faculty Advisor2015- Stanford Medicine Dean’s Fellowship Selection Committee

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Major Teaching Responsibilities:

University of Pennsylvania2007-2011 Member, Cell and Molecular Biology Graduate Group (Genetics & Gene Regulation)2007-2011 Member, Biology Graduate Group2008-2011 Member, Biochemistry and Biophysics Graduate Group2008-2011 Member, Neuroscience Graduate Group2007-2011 Lecturer, Neurobiology of Disease (INSC 587), graduate seminar course2007-2011 Lecturer, Cellular and Molecular Mechanisms of Neurodegenerative Diseases

(BIBB 480), graduate seminar course2007-2008 Lecturer, Seminar on current genetic research: Modeling Human Disease in

Diverse Genetic Systems (CAMB 534), graduate seminar course2009,2011 Lecturer, Biochemistry and Cell Biology (Bio 202), undergraduate lecture course2009-2011 Course Director, Seminar on current genetic research: Modeling Human Disease in

Diverse Genetic Systems (CAMB 534), graduate seminar course2009-2011 Lecturer, Human Embryology Module I, medical lecture course2009-2011 Course Director, Tutorial (BMB 598), graduate course2009 Instructor, Tutorial (BMB 598), met with two BMB graduate students to discuss

papers on protein misfolding and neurodegenerative diseases2009-2011 Lecturer, Topics in Conformational Diseases (CAMB 615/ BMB 518), graduate

seminar course2009 Lecturer, Advanced Cell Biology (Bio 480), undergraduate seminar course2010 Lecturer, Stem Cells, Science, and Society (HSOC 241/STC 241), seminar course for

upperclass UPenn undergraduates that are not majoring in the sciences2010 Instructor, Tutorial (BMB 598), met with two BMB graduate students to discuss

papers on genetic models of human diseases2010 Lecturer, academically based community service (ABCS) course in regenerative

biology2011 Instructor, Tutorial (CAMB 698), met with one BMB graduate student to discuss

papers on genetic models of human diseases

Stanford University2012- Course Co-Director, Molecular Mechanisms of Neurodegenerative Disease

(Biological Sciences/Neurology/Genetics 267; Winter quarter), graduate seminar course on the latest insights into neurodegenerative disease mechanisms (lecture + journal club)

2012 Lecturer, Methods and Logic in Experimental Genetics (Gene 222; Winter quarter), assisted in discussion of yeast genetics approaches

2012 Lecturer, Personalized Medicine and Genomics (Gene 210; Spring quarter), gave a lecture on latest genomics insights into human neurodegenerative diseases

2013-2015 Course Co-Director, Personalized Medicine and Genomics (Gene 210; Spring quarter), give lectures on latest genomics insights into human neurodegenerative diseases and organize class lectures and assignments

2013- Lecturer, Advanced Molecular Biology (Bio 104/200), undergraduate course2013 Lecturer, The Human Genome and Disease (Bio 109A/209A), undergraduate course

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2013 Lecturer, Genetics for Neurology Residents, a mini course on neurogenetics for Stanford neurology residents

2013, 2015 Lecturer, Advanced Genetics (Gene 203; Winter quarter), assisted in discussion of research papers on yeast genetic screening

2014- Lecturer, Human Molecular Genetics (Gene 271; Autumn quarter), give a lecture to genetic counseling students on neurodegenerative disease genetics

2015- Course Director, Neurogenetics (NEPR 213), introductory genetics course for first year Stanford Neuroscience graduate students

Trainees:

2007-2008 Zinaida Dedeic, Independent Study (now in PhD Program, University of Chicago)2007-2009 Andrew Elden, Research Specialist (now in MD Program, University of Medicine

and Dentistry, New Jersey)2007-2010 Jonathan Lee, Undergraduate research (now in Teach for America)2007-2011 Zhihui Sun, Postdoctoral Fellow2007- Alessandra Chesi, Postdoctoral Fellow2007 Xiwen Chen, Rotation Student (CAMB)2008-2009 Qi Zheng, Rotation Student (Biology)2008-2009 Ahrim Shin, Research Specialist (now in MD Program, East Tennessee State Medical

School)2008-2009 Austin Kilaru, Research Specialist (now in MD Program, University of Pennsylvania

School of Medicine)2008 Xiang Sarah Zhang, Undergraduate research2009 Yi Wang, Rotation Student (CAMB)2008-2012 Michael Hart, Graduate Student (Neuroscience, won 2012 Flexner Prize) (now

postdoc at Columbia University, Oliver Hobert lab)2009 Maria Armakola, Graduate Student (Neuroscience) (now postdoc at Harvard

Medical School, Gary Ruvkun lab)2009 Sarah Rong Fu, Undergraduate research2009-2011 Xiaodong Fang, Postdoctoral Fellow2007-2010 Brian Johnson, Research Specialist, Graduate Student (CAMB)2009- Daniel Ramos, High School Student, PENN undergraduate (Now Ph.D. student in

neuroscience at Johns Hopkins)2009- Xiaoying (Annie) Liu, Undergraduate research2009-2011 Divya Hosangadi, High School Student (Now Masters in Public Health student at

Johns Hopkins)2009-2010 Niti Jethava, High School Student2009-2010 Jake Epstein, High School Student2009-2010 Esther Kim, PENN undergraduate (won Joseph Leidy Award for Research

Achievement for undergraduate thesis research in my lab)2009-2010 Rachel Oristano, Research Specialist2009 Renske Erion, Rotation Student (CAMB)2009 Lauren Stutzbach, Rotation Student (Neuroscience)2010- Julien Couthouis, Postdoctoral Fellow2010-2011 Ashley Chiang, High School Student, Princeton Undergraduate

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2010-2011 Brittany Hodges, High School Student (now undergraduate at Brown University)2010 Yun Rose Li, Rotation Student (CAMB, MD/PhD program)2010-2011 Teresa Lee, Research Specialist (now in MD Program, University of Texas

Southwestern Medical School; selected for HHMI Medical Research Fellows Program)

2010 Michael Fleming, Rotation Student (Neuroscience)2011 Pierce Nathanson, Rotation Student (VMD/PhD program)2011- Ritu Chakrabarti (PENN undergraduate)2011 Thomas Rose, St. Joseph’s University Undergraduate summer intern2011- Julie Sung, Research Specialist2011 Elaine Liu, Rotation Student (Penn Neuroscience)2011 Maria Fasolino, Rotation Student (Penn Neuroscience)2011-2014 Alya Raphael, Postdoctoral Fellow (now Instructor in Stanford Communications

Department)2011-2015 Matthew Figley, Graduate Student (Stanford Neuroscience, won 2014 Sammy Kuo

Prize) (now postdoc at Washington University in St. Louis, Aaron DiAntonio’s lab)2012-2016 Ana Jovičić, Postdoctoral Fellow (now Scientist, Genentech)2012-2014 Nripesh Dhungel, Postdoctoral Fellow (now Product Development at Singer

Instruments)2012 Diane Chao, Wellesley College Undergraduate2012 Vidya Raghvendra, High School Student2012- Anna Thomas, High School Student2012-2013 Jacob Stillman, High School Student2012 Katherine Carr, High School Student (Stanford SIMR program)2012 Thomas Ward, Rotation Student (Stanford Genetics)2012- Gregor Bieri, Graduate Student (Stanford Neuroscience)2013 Anne Sapiro, Rotation Student (Stanford Genetics)2013 Biafra Ahanonu, Rotation Student (Stanford Biology)2014- Nicholas Kramer, Graduate Student (Stanford Neuroscience)2014- Lindsay Becker, Graduate Student (Stanford Neuroscience)2014 Alex Dainis, Rotation Student (Stanford Genetics)2014 Stuti Vishwabhan, High School Student2014-2015 Michael Zhao, High School Student2014-2015 Joseph West Paul III, East Carolina University Undergraduate (now Ph.D. student

at UC Berkeley)2014 Lilly Phillips, Stanford Undergraduate2014- Shizuka Yamada, Graduate Student (Stanford Biology)2015- Noori Chai, Graduate Student (Stanford Neuroscience)2015 Sharon Yuan-Fu Lu, Rotation Student (Stanford Neuroscience)2015- Brenda Huang, Postdoctoral Fellow2015 Olivia Zhou, University of Pennsylvania Undergraduate2015 Matthew Erman, High School Student2015-2017 Min Deng, Visiting Scholar (Peking University Third Hospital)2015- Jacob Blum, Graduate Student (Stanford Neuroscience)2016 Roy Moh Lik Ang, Rotation Student (Stanford Genetics)2016- Sophia Bechek, Stanford Med Scholars Student

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2016- Tai Dinger, Stanford Undergraduate (Bio-X Summer Fellowship recipient)2016 Sahara Naini, High School Student2016- Maya Maor-Nof, Postdoctoral Fellow2016-2017 Xiaoliu Liu, Visiting Scholar (Peking University Third Hospital)2017- Steven Boeynaems, Postdoctoral Fellow2017 Qijing ChiChi Xie, Rotation Student (Stanford Neuroscience)

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