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CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham University Hospital Accredited Mediator (LSM) Visiting Professor Nottingham Trent University Smart Design

CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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Page 1: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

page 1

CURRICULUM VITAEProfessor Michael H J VLOEBERGHSMD (VUBrussels), PhD (UoNottingham)

Consultant Paediatric NeurosurgeonNottingham University Hospital

Accredited Mediator (LSM)

Visiting Professor Nottingham Trent UniversitySmart Design

Page 2: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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CONTENT INDEX:

SUMMARY page 3

CLINICAL PRACTICE page 3

RESEARCH page 3

MEDICO-LEGAL WORK page 4

PERSONAL DETAILS page 4

QUALIFICATIONS page 5

PREVIOUS APPOINTMENTS page 5

CURRENT POST page 6

SOCIETIES page 6

TRAINING page 7

ACADEMIC ACTIVITY page 7

SUPERVISOR page 11

AWARDS page 12

PUBLICATIONS page 12

ELECTRONIC PUBLICATIONS page 24

PRESENTATIONS page 25

MEDIA PRESENTATIONS page 34

REQUEST ARTICLES page 34

POSTERS page 35

REVIEWS AND EDITORIAL WORK page 36

TEACHING page 37

CURRENT PRACTICE page 40

GRANTS page 42

INDUSTRIAL SPONSORSHIP page 42

OBJECTIVES page 43

INTERESTS page 43

Page 3: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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SUMMARY:

I am a Flemish Belgian, born in Brussels on 2/7/1959. My father was an Econimist and moved our family to Washington DC, USA, to take up a post in the International division of the Worldís Bank.I spent my early childhood in the US and went to a French Lyceum there. The family returned to Belgium, where I completed my education and went to medical school.

I started my medical studies at the Vrije Universiteit Brussel (VUB) in 1977 and qualified as a General Practitioner in 1985. I then first trained in General surgery with an option to become an orthopaedic surgeon. I have experience in plastic, orthopaedic, cardiovascular and digestive surgery. In was the A&E surgeon at the VUB for 6 months.

When a Neurosurgical post became available I changed my training schedule. I began Neurosurgical training at the French speaking Universite Libre de Bruxelles (ULB), continuing the training at the Flemish speaking Vrije Universiteit Brussel. I finished my training as a Paediatric Neurosurgeon at the Nottingham University Hospital in 1993.

I became a Consultant neurosurgeon with subspecialty in Paediatrics at the VUB in 1993, post I held until I was offered my current position at the Nottingham University Hospital. I am an exclusive Paediatric Neurosurgeon and as I cover 50% of the on call for Paediatric Neurosurgery i deal with all types of childhood disorders. My planned practice focuses on the treatment of spasticity, largely due to cerebral palsy-birth injury.

I also take part in the general Neurosurgery on call where I deal with emergency Neurosurgery in adults.

CLINICAL PRACTICE:

My clinical practice focuses on movement disorder in children, result of cerebral palsy or acquired brain injury. I have developed techniques for the treatment of hydrocephalus and spasticity and have performed foetal surgery.

With increased demand for treatment of spasticity and movement disorder I reconfigured my activity and increased my clinical practice.

My main clinical focus is the treatment of movement disorder in cerebral palsy e.g. spasticity by means of Selective Dorsal Rhizotomy (SDR) and Intra Thecal Baclofen (ITB) pumps. At the present we have a subdivision of functional neurosurgery that deals with movement disorder in children and adults and covers the entire treatment range e.g. Deep Brain Stimulation, Selective Dorsal Rhizotomy, IntraThecal Baclofen and spinal cord stimulation.

RESEARCH:

I run a longstanding research program into the flow of cerebrospinal fluid in collaboration with Mechanical Engineering at the University of Nottingham. This particular project has direct impact on the treatment of brain cancer and movement disorder in children by mapping the distribution of drugs directly injected into the nervous system.

Because of my particular interest in Engineering I was asked to join the Nottingham Trent University as a visiting Professor in the “Smart Design” program. This program applies novel technology from all fields into society and medicine in particular. This program allowed me to reacquaint with former colleagues of the Rutherford Appleton Laboratories, where I was a Special Scientific Advisor.

Page 4: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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MEDICO-LEGAL WORK:

I have involved as an expert witness in medico-legal work since 1993. I currently provide approximately 50 reports per year spread between 40% claimant, 40% defendant and 20% single joint expert.

I attend court as an expert witness approximately 5 times per year regarding child care proceedings, criminal cases (non-accidental injury), clinical negligence and family law cases.

I have a particular interest in brain damage related to birth injury and the majority of negligence cases I’m asked to review regard cerebral palsy related to birth incidents.

Exceptionally I accept medico-legal cases regarding adult motorcycle accidents, because of my own 40 year motorcycle experience.

I’m an accredited Mediator (LSM) and am continuing to be involved in Mediation as a generic skill.

PERSONAL DETAILS:

Name: Michael Hendrik Jan Vloeberghs

Date of Birth: 2 July 1959

Nationality: Belgian

Marital Status: Married to Herlinde, 3 children

Title: Professor

Professional Address: Paediatric Neurosurgery Nottingham University Hospital Nottingham NG7 2UH United Kingdom Work Tel: 0044/01159 249 924 Ext 63635

E-Mail: [email protected]

GMC Number: 3620919 since 1992

Specialist Register: Neurological Surgery since 10/6/1996

CCST Date: 15 / 7 / 1993

BMA Number: 7852650

Page 5: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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QUALIFICATIONS:

1985 Medical Degree, Vrije Universiteit Brussel MD with High Honours, Vrije Universiteit Brussel Infectie Bij de Totale Heupprotese

Degree in Hospital Medicine and Management

1993 Neurosurgical Accreditation

2000 PhD University of Nottingham Neuroendoscopic Third Ventriculostomy in the Management of Childhood Hydrocephalus

2002 A.T.L.S Nottingham

2003 ATLS Instructor Course, RCS London

2012 Visiting Professor, Nottingham Trent University 2012 Accredited Mediator, London School of Mediation

PREVIOUS APPOINTMENTS:

General Internship Academisch Ziekenhuis Vrije General Surgery 01/07/85 - 30/06/88 Universiteit, Brussel Prof G Willems

Neurosurgical Internship Hopital Erasme General Neurosurgery01/07/88 - 30/09/89 Universite Libre de Bruxelles Prof J Brotchi

Neurosurgical Internship Academisch Ziekenhuis Vrije General Neurosurgery01/10/89 - 30/09/92 Universiteit, Brussel Prof J D`Haens

Senior Registrar Queens Medical Centre, Paediatric Neurosurgery01/10/92 - 30/07/93 Nottingham Mr J Punt

Consultant Academisch Ziekenhuis Vrije General and Paediatric 01/09/93 - 01/07/95 Universiteit, Brussel Neurosurgery

Page 6: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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CURRENT POST

Consultant Paediatric Neurosurgeon Nottingham University Hospital Date of Appointment 01/10/95

Visiting Professor Nottingham Trent University 2012

Accredited Mediator (LSM) 2012

SOCIETIES

Society of British Neurological Surgeons

Society of British Functional Neurosurgeons (Sub. SBNS)

British Paediatric Neurosurgery Group

UK Register of Expert Witnesses

British Medical Acupuncture Society, COC 2000

Institute of Neurosciences, University of Nottingham

Member of the European Advisory panel for Intrathecal Baclofen

Mid-Trent Cancer Network, Central Nervous System Group

Member of the Scientific Board of the International Study Group on Neuroendoscopy

Founding member of the UK ITB steering group (2006)

Founding member of the European ITB steering group (2007)

Member of the National Steering group for Selective Dorsal Rhizotomy (2013)

Page 7: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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TRAINING

My early education took place in the Lycee Francais in Washington DC, USA, where my father worked in the World’s Bank. I returned to Brussels where I completed my education in the Belgian- Flemish state system. My general medical training was at the Vrije Universiteit Brussel where I also started my general surgery training and later diverged into neurosurgery. My neurosurgical training was at the Universite Libre de Bruxelles with Professor Brotchi and the Vrije Universiteit Brussel with Professor D’Haens.

In 1992 I undertook a year of specialist training in Paediatric neurosurgery at Queens Medical Centre, Nottingham, United Kingdom. In 1993 I returned to the Vrije Universiteit Brussel and joined Professor D’Haens in a part adult part Paediatric practice.

In 1995 I was offered the position, which I currently occupy, at the University of Nottingham as Senior Lecturer in Paediatric Neurosurgery and Honorary Consultant Paediatric Neurosurgeon. General changes in practice volume in 2012, with the increase in cerebral palsy work I needed to shift to the NHS. My Academic activity is now related to the Nottingham Trent University where i am a visiting Professor part of the “Smart Design” Group.

The Nottingham University Hospital is the teaching hospital of the University of Nottingham. As a large regional centre our current catchment area has a population of 5,5 million people, for Paediatric Neurosurgery, encompassing the area known as the East Midlands up to the east coast. The paediatric practice has a much broader4 catchment area with International referrals. There are currently between 200-250 paediatric neurosurgical operations and 500-day cases performed per year.

ACADEMIC ACTIVITY

RESEARCH

PhD. Neuroendoscopic Third Ventriculostomy in the Management of Childhood Hydrocephalus

I was awarded the degree of PhD in July 2000 for my thesis based on my clinical and experimental experience with Neuroendoscopic Third Ventriculostomy (NTV). This incorporated a clinical and statistical analysis of my experience with Neuroendoscopy as well as piloting the use of ultrasound Doppler technology in NTV. The statistical analysis by means of multivariate analysis led to a normogram predicting the outcome of NTV according to age and aetiology of hydrocephalus. This normogram is used in the counseling of parents and patients confronted with the management of childhood hydrocephalus.

The thesis was supervised by Professor A Moody and examined by Professor J Wood (Nottingham) and Professor A Whitelaw (Bristol).

The Application of Information Technology in Medicine

Virtual Reality: As a research partner of the Centre for Industrial and Medical Imaging (CIMI) of the University of Nottingham I am involved in virtual reality rendering of radiological images in fly through mode (for further information: http://www.cimi.nottingham.ac.uk/). This real time fly through model remains unique, as no other research team has been able to reproduce these images.

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An original CISS sequence (Siemens¨©) was used to reconstruct a mesh image of my ventricular system. This mesh was then coated and stochastic rendering techniques based on video images were used to “wall-paper” the inside of the structure.

No graphics or smoothing routines were used to create the model. This automated reconstruction technique can be seen as a preliminary to creating patient specific images, which can be used for teaching or simulation exercises.

Tactile Simulation of Brain Surgery: This work stems from my pervious experience in VR and the combination of the mathematical skills of Dr A. Jones and Prof. Becker and the computer science department, Prof. Benford. This project is funded by a ¨£300000 EPSRC grant and aims to give tactile feedback to a VR image of the brain.

The project was concluded in 2007 and led to a pre-commercial simulator. The project has been well publicised and received a B mark assessment from EPSRC. (For references see publications.)

Simulation of head injury specifically Shaken Baby Syndrome: This research done in partner hip with Dr D McNally, Biomechanical engineering aims to mathematically and experimentally simulate, injury to the brain specifically in cases of child abuse.

The work is based on reverse engineering of MRI images and experimental data obtained through physical simulation.

Computational Fluid Dynamics (CFD): The follow-on of this technical progress has been the setting up of a multidisciplinary research project to study the flow of cerebrospinal fluid (CSF) through the human ventricular system in both virtual reality and on a rapid prototyped model.

In this project, run jointly with Dr. Aroussi (Dept of Engineering, University of Nottingham), we have begun the study of the flow of the CSF through the human ventricular system. The study is based on the use of Computational Fluid Dynamics and a suction moulded Perspex model, which can be studied with Laser Doppler analysis. Preliminary results have been presented at National and International meetings and show the impact the shape of the ventricular system has on the regular CSF flow. This work is expanding and we are now building physical simulation units. Work was first done on simplified, box like, geometries but building on my previous experience with MRI data and rapid prototyping, a 5:1 and later a 10:1 model of the human ventricular system is built. We aim to diversify into drug delivery, both spinal and intraventricular along with CSF-flow studies. We have demonstrated stagnation pools in the ventricular system, which will lead to a rethinking of intraventricular drug delivery in the future. (For references see publications.)

Digital Healthcare Community: This Information Technology project is the piloting of a digital healthcare community, which includes medical education, patient information and remote telemedical facilities. With the help of a grant of £10000 from the special trustees of Queens Medical Centre and the cooperation of Nottingham Telephones, a Telelink has been set up between the neurosurgical theatres and the neurosurgical library for teaching purposes. A parallel link also runs between me theatres and the neuropathology department. These links allow real-time, two way communication between the sites and allow, as an example, the pathologist to see the surgical biopsy site and the surgeon to view the frozen section.

The system has meanwhile evolved to a real time communication centre use wekly for cancer MDT meetings.

Page 9: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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Foeto-Maternal Medicine:

Human: In March 1997 I was asked by Professor Kyphros Nicolaides, Kings College London, to participate in an In-Utero procedure in a human subject. After appropriate consent and ethical approval we performed a Neuroendoscopic Third Ventriculostomy on a human foetus of 23 weeks gestation with hydrocephalus of an aqueduct stenosis pattern.

On a clinical basis I run an ad hoc, foetomaternal medicine service which provides Neurosurgical input to couples with foetuses with birth defects. This service runs in close collaboration with Neuroradiology and foetomaternal medicine specialists.

Sheep: This above exceptional procedure sparked the interest of Professor Yves Ville at the foeto-maternal medicine unit in Poissy, Paris. Professor Ville dedicated funds through the Euro-foetus network to forward an experimental study on gestating sheep.

The Flossie project consisted of :

1 Creating hydrocephalus in the foetus by the injection of maternal blood into the brain of the foetus at a human equivalent gestational age of approximately 22 week.2 Inserting an endoscope into the dilated ventricles of the foetus at an equivalent age of approximately 32 weeks 3 Injecting human amniotic fluid into the brain parenchyma of a number of foetuses to assess the effect upon the brain. (For references see publications.)

Infrared Spectroscopy: In collaboration with Professor M Chesters, Dept of Chemistry, University of Nottingham, a pilot study has been started to study the use of infrared spectroscopy in brain tumours. The intention of the experiment is to detect infrared spectra that will be specific to the grade of malignancy of the tumour, which in turn may have implications for the surgical technique and ultimately the treatment. Preliminary results showed that the spectra are specific to the area that has been biopsied but further examination on larger numbers is necessary and in progress.

Rutherford Appleton Laboratories (RAL):

Nano-Technology: I am a Special Scientific Advisor at RAL in agreement with the School of Human Development. My main contact is Professor J Wood with whom I have collaborated for several years on the biomaterials applications front as a medical end user. I participate in the think-tank meetings where applications are sought for the technologies available in the central microstructure facility. This has led to a close collaboration with Dr R Stevens at the RAL with promising applications of nano-technology in medicine.

Space Programme: As a special interest I evaluate the state of space medicine and what contribution can be made to acute injury in space, specifically with regards to the International Space Station. As a spin-off I have found a useful parallel between astronautic procedures and risk management in the NHS. This is being explored at the present and both branches of risk avoidance and risk management will prove to be mutually beneficial.

Page 10: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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Presentation on Space Medicine: Invited lecture at the UK Space Medicine Day, Space School Leicester, August 11, 2004. Injury in Microgravity, a review of the literature and the state of the art of Medicine in Space.M. Vloeberghs

Invited lecture at the Space Research Centre, University of Leicester, 11/2004.Injury in Microgravity.M. Vloeberghs

CD-Rom:

Presented at the Space School Leicester, 11 August 2004.Injury in MicrogravityM. Vloeberghs

Poster presentation:

UK Space Medicine Day, 11 August 2004.Risk Management in Health Care and Space MedicineWith M. Cartmill.

Paper:

Physical Injuries in Micro-gravity.M. VloeberghsPublihed by; The Leicester Space School. August 11, 2004.Current projects:

Clinical:

1. Continuous update and audit of the Baclofen program. 2. Investigator in the Pan-European clinical outcome study on ITB.3. Participation in the UK, Vagus Nerve Stimulator RCT.4. Pilot study on the use of intra-operative Ultrasound Doppler in Neuroendoscopy.5. Lead investigator in a Nottingham based national RCT, for the evaluation of the efficacy of Intrathecal Baclofen in spasticity in children. In collaboration with Dr. R. Morton Consultant Paediatrician.6. Coordinator of the European ITB study on Ambulant Children.7. Intrathecal Chemotherapy (ITC) in relapsed Medulloblastoma. In collaboration with Prof. R. Grundy, Prof. D. walker.8. Reestablishing vascular supply to the brain in children with Sickle Cell Anemia-Vasculitis. In collaboration with Prof. D. Walker, Dr K. Forman.9. Establishing an SDR activity in Nottingham using the single level approach in all GMFCS groups. The SDR activity is part of a continuous audit and I am part of the National commissioning group for SDR. (CTE 2013)

Page 11: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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IT:

1. Expansion and updating of the ISDN based intra-hospital network in collaboration with Nottingham telephones.2. Development of a Tactile Virtual Reality Phantom. In collaboration with Dr A Jones, Department of Engineering, Nottingham.3. Spin-off project into visualisation of surgical images in VR for training purposes. Prof. S. Benford, T. Glover.4. Simulation of NA injury using computational techniques. Dr. D. McNally, D. Wolfson.

Nanotechnology:

1. Intelligent catheters with self-cleansing capacity. (RAL)2. Intelligent drug delivery systems. (RAL)3. Internal power sources based on natural motion of CSF and muscle. (RAL)4. Neural interfaces & scaffolding (RAL)5. Single Cell Laboratory6. Serotonin Sensing in the brain.

Generic:

1. Infrared spectroscopy of human brain tumour samples in collaboration with Prof. M. Chesters (Chemistry)2. Simulation of shaken baby syndrome with Dr D. Macnally. Completed PhD by David Wolfson 2006.3. Simulation of the activity of the Deep Nuclei of the brain, aiming to simulate the electrical activity in Parkinson disease and dystonia with Dr D. Giddings.

SUPERVISOR

Since my appointment I have been keen to develop cross specialty and cross discipline training. I currently supervise the work of the following PhD and undergraduate engineers.

PhD: The Fluid Hydrodynamics of the Human Ventricular System. M. Zainy, 2003

PhD: CSF dynamics in a simplified model of the human ventricular system. Shatha Amourrah, 2004

Undergraduate: 2- Dimensional Simulation of Cerebrospinal Fluid Flow. R Deaming, L Fossey, J Towe

J Towe received the first prize in the medical engineering competition, Cambridge 1999.

Mphil: 3-D Modelling of the ventricular system & CSF flow, L. Howden. 2002-2003

PhD, David Wolfson: Simulation of Non accidental injury. 2003- 2006

PhD, Leo Howden: CSF circulation in the human ventricular system. 2007

PhD, Amr Ammar: ITB in the management of childhood spasticity. 2009

PhD, Jonathon Thewlis: Validation of CSF flow model with MRI. 2009-2011

Page 12: CURRICULUM VITAE - Professional Witnesses€¦ · CURRICULUM VITAE Professor Michael H J VLOEBERGHS MD (VUBrussels), PhD (UoNottingham) Consultant Paediatric Neurosurgeon Nottingham

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AWARDS

1. The British Medical Association Film Competition Certificate for Educational Merit BIMA Award 1998 An Introduction to Neuroendoscopy CD-ROM As 2nd Messenger Ltd with Hypertech Multimedia Ltd.

2. Stand Presentation at IPOT1997, Birmingham Image Processing, Machine Vision, Microscopy CD-ROM in Surgical Training

PUBLICATIONS

1. Traumatic Rupture of the Thoracic Aorta M Vloeberghs, B Cham. Acta Chirurgica Belgica 1988; 88: 33-38

2. A Patient with Two Chronic Posttraumatic Aneurysms of the Thoracic Aorta F Caes, B Cham, J Sacre, V Ponikelski, M Vloeberghs, W Welch Thorac and Cardiovasc Surg 1989; 37(2): 105-106

3. Solitary Dorsal Intramedullar Schwannoma. A Case Report and Review of the Literature P Herregodts, M Vloeberghs, E Schmedding, A Goossens, T Stadnik Journal of Neurosurgery 1991; 74(5): 816-820

4. De Craniosynostose en Haar Behandeling M Vloeberghs, D’Haens. Tijdschrift Voor Geneeskunde 1991; 47(23), 1607-1611

5. Spinal Arachnoiditis Mimicking a Spinal Cord Tumour. A Case Report and Review of the Literature M Vloeberghs, J D’Haens. Surg Neurol 1992; 37: 211-215

6. Acute Management of Posthaemorrhagic Hydrocephalus in the Preterm Infant M Vloeberghs, J D’Haens. Child`s Nerv Syst 1992; 8: 173-174

7. A Patient with Two Upper Lumbar Disc Herniations M Vloeberghs, J Noterman, M Levivier, D Baleriaux, J Brotchi Acta Orthopedica Belgica 1992; 58(3): 340-342

8. An Uncommon Evolution of a Neurogenic Sarcoma M Vloeberghs, R Sacre, A Goossens, A Michotte, J D`Haens Acta Neurologica Belgica 1992; 92: 157-164

9 The Value of Stereotactic Procedures in Children M Vloeberghs, D Jellinek, K Robson, G Turner, J Punt Child`s Nerv Syst 1993; 9: 362

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10. The Value of Stereotactic Brain Biopsy in Paediatric Neurosurgery D Jellinek, M Vloeberghs, G Tuner, K Robson, J Punt J Neurol Neurosurg Psychiatry 1993; 56(12): 1336

11. Management of Multifocal Primitive Neuroectodermal Tumours M Vloeberghs, J Punt, J Leggate, D Walker, M Sokal, T Jaspan, K Robson Medulloblastoma 1993. Proceedings of the 5th International Symposium on Paediatric Neuro-Oncology and the 2nd Consensus Conference on Paediatric Neurosurgery 1993

12. Transorale Toegang Van de Hoge Cervicale Zuil: 2 Gevallen M Vloeberghs, J Vangeneugden, J De Keizer, N De Klippel, J D`Haens Acta Neurologica Belgica 1994; 94: 212

13. Third Ventriculostomy Using the “Air Bubble” Technique M Vloeberghs, J Vangeneugden, T Stadnik, J D`Haens Acta Neurologica Belgica 1995; 95: 119

14. Endoscopic Retrieval of a Blocked Ventricular Catheter and Endoscopic Catheter Reinsertion M Vloeberghs, J Vangeneugden, J D`Haens Acta Neurologica Belgica 1995; 95: 121

15. Neuroendoscopy in the Management of Childhood Hydrocephalus J Punt, M Vloeberghs J Neurol Neurosurg Psychiatry 1996; 61: 228

16. The Teaching of Neuroendoscopy by Computer Assisted Learning (CAL) M Vloeberghs, J Punt, MTerrett Acta Neurologica Belgica 1996; 96

17. A Computer Assisted Learning Program for Neuroendoscopy M Vloeberghs, J Punt, M Terrett www.igs.wiley.com 4/1996. Image Guided Surgery online section

18. Neuroendoscopy. The Renaissance M Vloeberghs International Federation for Hydrocephalus and Spina Bifida (IFHSB) Federation Focus 1996:11

19. Computer Assisted Learning in Neuroendoscopy M Vloeberghs, J Punt, M Terrett Child`s Nerv Syst 1996; 12: 365

20. A Computer Assisted Learning Program for Neuroendoscopy J Punt, M Vloeberghs, M Terrett Child`s Nervous System 1996; 12: 485

21. Neuroendoscopy.The Renaissance M Vloeberghs International Federation for Hydrocephalus and Spina Bifida (IFHSB) Federation Focus 1997: 22

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22. Third Ventriculostomy. Reinventing the Wheel M Vloeberghs LINK Magazine. Hydrocephalus Network News 1997: 168

23. Third Ventriculostomy and Flying M Vloeberghs Lift Magazine 1997; Autumn: 8

24. A Neuroendoscopic Approach to Lilliequist`s Membrane N Buxton, M Vloeberghs, J Punt Clin Anat 1997; 10(5): 353

25. Should Shunts be Revised When Neuroendoscopic Third Ventriculostomy is Available? C Mallucci, M Vloeberghs, J Punt Br J Neurosurg 1997; 11: 473

26. Liliequistís Membrane. A Re-examination of its Importance N Buxton, M Vloeberghs, J Punt Surgical and Radiological Anatomy, J Clinical Anatomy 1997; 19(4) Suppl: 14

27. A Virtual Reality Model of the Human Ventricular System M Vloeberghs, F Hatfield, F Daemi Computer Integrated Surgery 1997; Suppl ISSN 1092-9088

28. A Rapid Prototype Model of the Human Ventricular System M Vloeberghs, F Hatfield, F Daemi Computer Integrated Surgery 1997; Suppl ISSN 1092-9088

29. Computer Assisted Learning Packages in Neurosurgery M Vloeberghs, M Terrett, J Punt Computer Aided Surgery 1997; 2(5): 298

30. Neuroendoscopic Third Ventriculostomy: The First Line Treatment for Blocked Ventriculo-Peritoneal Shunts? C Mallucci, M Vloeberghs, J Punt Childís Nerv Syst 1997; 13: 498

31. Neuroendoscopic Third Ventriculostomy: The First Line Treatment for Blocked Ventriculo-Peritoneal Shunts? C Mallucci, N Buxton, M Vloeberghs, J Punt Eur J Pediatr Surg 1997; 7( suppl 1): 111

32. A Computer Assisted Learning (CAL) Package for Neuroendoscopy M Vloeberghs, J Punt, M Terrett Br J Neurosurg 1998; 12: 504

33. Monstrous Skull Osteomas in a Probable Case of Gardnerís Syndrome: Case Report J Noterman, N Massager, M Vloeberghs, J Brotchi Surg Neurol 1998; 49(3): 302-305

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34. Neuroendoscopic Third Ventriculostomy in the Management of Childhood Hydrocephalus M Vloeberghs Proceedings of the International Symposium on Spina Bifida 1998, MS No 11-3-4

35. Slit Ventricle Syndrome M Vloeberghs LINK Magazine. Hydrocephalus Network News 1998; 173: 3

36. Neuroendoscopic Ventriculostomy for Childhood Hydrocephalus. 1998 Update M Vloeberghs Back Up 1998; 27: 7

37. Primary Neuroendoscopic Third Ventriculostomy for Hydrocephalus N Buxton, C Mallucci, D Macarthur, I Robertson, M Vloeberghs, J Punt Br J Neurosurg 1999; 13(2): 227-228

38. Liliequistís Membrane in Minimally Invasive Endoscopic Neurosurgery N Buxton, M Vloeberghs, J Punt. Clin Anat 1998; 11(3): 187-190

39. Ruptured Fusiform Cerebral Aneurysm in a Neonate M Tan, N McConachie, M Vloeberghs Childís Nerv Syst 1998; 14(9): 467-469

40. Primary Neuroendoscopic Third Ventriculostomy for Hydrocephalus N Buxton, C Mallucci, D Macarthur, I Robertson, M Vloeberghs, J Punt Br J Neurosurg 1999; 16(4): 312

41. Soft Tissue Rapid Prototyping in Neurosurgery M Vloeberghs, M Daemi, f Hatfield, P Dickens Computer Aided Surgery 1998; 3(2): 95-97

42. Neuroendoscopy in the Premature Population N Buxton, D Macarthur, C Mallucci, J Punt, M Vloeberghs Childís Nerv Syst 1998; 14(11): 649-652

43. Neuroendoscopy in Children Under One Year of Age M Vloeberghs, J Punt Minim Invas Neurosurg 1998; 41: 126

44. A Virtual Reality Model of the Human Ventricular System M Vloeberghs, F Daemi, J Demeshki, F Hatfield Minim Invas Neurosurg 1998; 41: 126

45. Primary Neuroendoscopic Third Ventriculostomy in Patients Less Than One Year of Age. N Buxton, D McArthur, C Mallucci, J Punt, M Vloeberghs Eur J Paediatr Surg 1998; 8(Suppl 1): 9

46. Neuroendoscopic Third Ventriculostomy in Patients Less Than One Year Old N Buxton, D Macarthur, C Mallucci, J Punt, M Vloeberghs Pediatr Neurosurg 1998; 29(2): 73-76

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47. The Role of Neuroendoscopy in the Management of Brain Tumours D Macarthur, N Buxton, J Punt, M Vloeberghs Medical and Pediatric Oncology 1998; 31(4): 204

48. The Role of Neuroendoscopy in the Management of Brain Tumours D Macarthur, N Buxton, J Punt, M Vloeberghs J Neuro-Oncology 1998; 39(2): 105

49. Listeria Monocytogenes Meningitis in a Penicillin-allergic Paediatric Renal Transplant Patient V Weston, J Punt, M Vloeberghs, A Watson, P Ispahani Journal of Infection 1998; 37(1): 77-78

50. Endoscopy in Neurosurgery J Punt, M Vloeberghs Min Invas Ther and Allied Technol 1998; 7(2): 159-170

51. Flexible Neuroendoscopic Treatment of Suprasellar Arachnoid Cysts N Buxton, M Vloeberghs, J Punt British Journal of Neurosurgery 1999; 13(2): 316-318

52. Improved Safety of Neuroendoscopic Third Ventriculostomy by Using an Operative Doppler Ultrasound Probe M Vloeberghs, M Cartmill Neurosurgical Focus 1999; 6(4): Article 13

53. Constructive Interference in Steady State in Neuroendoscopy R Laitt, C Mallucci, N McConachie, T Jaspan, M Vloeberghs, J Punt Neuroradiology 1999; 41(2): 117-123

54. Hydrocephalus in Poland. An inside view M Vloeberghs Back Up 1999: 7

55. Sinus Pericranii N Buxton, M Vloeberghs Pediatr Neurosurg 1999; 30(2): 96-99

56. Third Ventriculostomy M Vloeberghs Hydrocephalus and You. ASBAH 1999; 20-21

57. Slit Ventricle Syndrome M Vloeberghs Hydrocephalus and You. ASBAH 1999; 24-26

58. Neuroendoscopic Management of Shunt Complications M Vloeberghs, C Mallucci, J Punt Spina Bifida 1999; July: 207-211

59. 3-D Visualisation of the Human Ventricular System S Bassi, F Hatfield, J Demeshki, F Daemi, M Vloeberghs Br J Neurosurg 1999; 13(5): 526

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60. The Use of Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Eur J Paediatr Surg 1999; 9(Suppl 1): 50-51

61. The Use of Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy - a Video Presentation M Cartmill, M Vloeberghs Br J Neurosurg 2000; 14(3): 276

62. Third Ventricle Width Variations in Patients Undergoing Primary and Secondary Neuroendoscopic Third Ventriculostomies S Thomson, M Cartmill, M Vloeberghs Br J Neurosurg 2000; 14(3): 291

63. Endoscopic Third Ventriculostomy: Outcome Analysis of 100 Consecutive Procedures. Letter to the Editor N Buxton, M Cartmill, M Vloeberghs Neurosurgery 1999; 45(4): 957-959

64. Role of Repeat Neuroendoscopic Third Ventriculostomy (NTV) V Gonugunta, N Buxton, M Cartmill, M Vloeberghs Neurosurgery 2000; 47(2): 540

65. A Parametric Study of Cerebrospinal Fluid Flow in the Human Ventricular System M Vloeberghs, J Towe, M Zainy, M Cartmill, A Aroussi. Childís Nerv Syst 2000; 16(8): 535

66. The Use of Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Childís Nerv Syst 2000; 16(6): 380

67. Intrathecal Baclofen for the Management of Spasticity in Children with Cerebral Palsy within the United Kingdom M Vloeberghs, M Cartmill, S Bassi. Childís Nerv Syst 2000; 16(8): 540

68. Neuroendoscopic Third Ventriculostomies for Hydrocephalus in Adults N Buxton, K Ho, J Punt, M Vloeberghs, I Robertson Br J Neurosurg 2000; 14(1): 75

69. Multivariate Statistical Analysis to Predict Outcome in Neuroendoscopic Third Ventriculostomies M Vloeberghs, A Skene, M Cartmill Br J Neurosurg 2000; 14(5): 517

70. The Use of Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Childís Nerv Syst 2000; 16(8): 537

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71. The Fate of the Cerebrospinal Fluid after Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Childís Nerv Syst 2000; 16: 879-881

72. The Effectiveness of Intrathecal Baclofen in the Management of Patients with Severe Spasticity Co-author of the Working Group on Acute Purchasing, Trent Institute for Health Services Research Scharr Report on Intrathecal Baclofen Therapy 2000

73. Neuroendoscopic Third Ventriculostomy in Dysmorphic Brains M Cartmill, M Vloeberghs Childís Nerv Syst 2001; 17: 391-394

74. Neuroendoscopy in the Management of Brain Tumours D Macarthur, N Buxton, M Vloeberghs, J Punt Br J Neurosurg 2001; 15(1): 88

75. Neuroendoscopic Third Ventriculostomy for Hydrocephalus in Adults: Report of a Single Unitís Experience with 63 Cases N Buxton, M Vloeberghs et al Surg Neurol 2001; 55(2): 74-79

76. Multivariate Statistical Analysis to Predict Outcome in Neuroendoscopic Third Ventriculostomies M Cartmill, A Skene, M Vloeberghs. British Journal of Neurosurgery, October 2000, vol 14, No 5, p 517

77. The Use of Intrathecal Baclofen in the Management of Spasticity in Children with Cerebral Palsy M Vloeberghs, M Cartmill, S Bassi. B. British Journal of Neurosurgery, Dec 2001, vol 15, No 6 p546.

78. The effectiveness of neuroendoscopic interventions in children with brain tumours. D. Macarthur, N. Buxton, M. Vloeberghs, J. Punt. Childís Nervous System (2001) 17:589-594

79. A parametric study of cerebrospinal fluid flow in the human ventricular system. M. Vloeberghs, A. Aroussi, M. Zainy, M. Cartmill. Childís Nervous System (2000) 16, 8, 535

80. A virtual reality model of the human ventricular system. A. Aroussi, M. Vloeberghs, M. Zainy. 9th Millennium International Symposium on Flow visualisation, Edinburgh 2000, CD-ROM.

81. Cerebrospinal Fluid Dynamics. A. Aroussi, M. Zainy, M. Vloeberghs 9th Millennium International Symposium on Flow visualisation, Edinburgh 2000, CD-ROM.

82. The clinical outcome of the treatment of spasticity of cerebral origin with Intrathecal Baclofen varies with age. Early treatment is advised. M. Vloeberghs, M. Cartmill. Proceedings of the EANS winter meeting 2/2002, Adults and Children: Impact of the age on neurosurgical diseases.

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83. The influence of age, aetiology and procedure type on the outcome of neuroendoscopic third ventriculostomy assessed with multivariate analysis. M. Cartmill, M. Vloeberghs, A. Skene. Procedings of the EANS winter meeting 2/2002, Adults and Children:Impact of the age on neurosurgical diseases.

84. The Use of Intrathecal Baclofen in the Management of Spasticity in Children with Cerebral Palsy M Vloeberghs, M Cartmill, S Bassi. Child’s Nervous System, 2002; 18/8:540

85. Changes in third ventricular size with neuroendoscopic third ventriculostomy. N. Buxton, B. Turner, N. Ramli, M. Vloeberghs JNNP, Mar, 72 (3):385-387, 2001

86. The role of neuroendoscopy in the management of brain tumours. Vloeberghs M., Macarthur D, Robertson I. Br J Neurosurg. 2002, Oct, 16(5):465-70. PMID: 12498490

87. Intrathecal Baclofen in the management of spasticity due to cerebral palsy in children. M. Vloeberghs Requested by The Journal of the British Association of Bobath Trained Therapists. 3/2002

88. Intrathecal Baclofen in the management of spasticity in children. M. Vloeberghs Requested by Advances in Clinical Neuroscience & Rehabilitation. 6/2002

89. Experimental Hydrocephalus in Sheep: a validation experiment for neuroendoscopy. M. Vloeberghs, B. Dekeersmaecker, Y.Ville Childs Nervous System (2003), Vol. 19, No 7-8, 605

90. Aspects of the treatment of spasticity due to cerebral palsy in children with Intrathecal Baclofen. M. Vloeberghs, J. Fitzgerald, M. Tsegaye, M. Cartmill Childís Nervous System (2003), Vol. 19, no 7-8, 634

91. Management of Spasticity in Children with Cerebral Palsy, A National Randomised Controlled Study on Intrathecal Baclofen. Rachel Keetley, Richard Morton, Michael Vloeberghs. ACNR,Vol 4, no 1, p.16-19, March April 2004.

92. Intrathecal baclofen in the management of spasticity due to cerebral palsy. M. Vloeberghs, ACNR, vol 2, no 4, Sept 2002.

93. Treatment of childhood spasticity of cerebral origin with intrathecal baclofen: a series of 52 cases. J. Fitzgerald, M. Tsegaye, M. Vloeberghs. British Journal of Neurosurgery, June 2004.

94. Management of childhood spasticity with intrathecal baclofen. Requested by Paediatric Rehabilitation. M. Vloeberghs, R. Keetley, R. Morton. In Press, 6/2005.

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95. Rigid Body Modelling of Shaken Baby Syndrome in press with the Journal of Engineering in Medicine D R Wolfson, D McNally, M Clifford, M Vloeberghs Proceedings of the ID,IMechE Part H:J. Engineering in Medicine. H04204ImechE 2005, p 63- 70.

96. Application of the Boundary Element Method to the Simulation of Surgery including Haptic Feedback. Wang , P., Becker, A.A., Glover, A.T., Benford, S. D., Greenhalgh, C. M. , Vloeberghs M. and Jones, I. A. Proceedings of the Seventh International Conference on Computational Structures Technology, Lisbon, 7-9 September 2004, B.H.V. Topping and C.A. Mota Soares, (Editors), Civil-Comp Press, Stirling, 2004.

97. Cerebro spinal Fluid Dynamics in the Aqueduct of Sylvius Aroussi A, Zainy M, Vloeberghs M, Proceedings of the 9th International Symposium on Flow Visulisation. Edinburgh. 2000.

98. Simulation of Human Cerebrospinal Fluid Flow. Aroussi A, Vloeberghs M, Etchell S, Gransden J, Latimer R, Giddings D, Proceedings of the 11th International Symposium on Flow visualisation. Notre Dame University, 2004.

99. Physical and numerical modelling cerebrospinal fluid behaviour for drug delivery to the leptomeninges D. Walker, S. Ammourah, A. Aroussi, M. Garnett, D. Giddings, L. Howden, H. Power, & M.Vloeberghs. 6th Meeting of the European Association for Neuro-Oncology, Edinburgh, 2005

100. Intrathecal Baclofen in the management of spasticity due to cerebral palsy. M. Vloeberghs, R. Keetley, R. Morton, Pediatric Rehabilitation On Line. Taylor & Francis eds. DOI 10.1080/13638490400011165. 3/12/2004

101. Three Dimensional Cerebrospinal Fluid Flow Within the Human Ventricular System. Proceedings of PSFVIP-5 Howden L, Aroussi A, Vloeberghs M, , 5th Pacific Symposium on Flow Visualisation and Image Processing, 27-29 September, 2005, Australia.

102. Decision making in paediatric brain tumours a neurosurgical perspective. M. Vloeberghs, Current Paediatrics, Vol 15, Issue 5, p 406-411, Oct 2005.

103. Virtual Reality Surgery Simulation using Haptics and Boundary Element Techniques. Wang P., Glover T., BeckerA., Jones A., Benford S., Greenhalgh C. and Vloeberghs M, (World Haptics Conference, March 18-20, 2005. (Poster reproduced in proceedings, poster refereed)

105. Virtual reality simulation of surgery with haptic feedback based on the Boundary Element Method. P. Wang, A.A. Becker, I.A. Jones, A.T. Glover, S.D. Benford, C.M. Greenhalgh and M. Vloeberghs. Submitted in April 2005 to “Computers and Structures”.

107. Application of the Boundary Element Method to the simulation of surgery including haptic feedback. Wang P., Becker A.A., Glover A.T., Benford S. D., Greenhalgh C. M., Vloeberghs M. and Jones I. A., Accepted for presentation at Seventh International Conference on Computational Structures Technology, Lisbon (CST 2004), 7-9 September 2004 (11 pages)

108. Designing a Virtual Reality Simulator for Neurosurgery. Wang P., Becker A. A., Glover A.T., Jones I. A., Benford S. D., Vloeberghs M. and Greenhalgh C. Virtual Reality International Conference, 18 - 22 April 2005, Laval, France (5 pages, paper refereed)

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109. 3-D Visualisation of fluid flow within the human centreal nervous system. A. Arousi, L. Howden, M. Vloeberghs. Proceedings of the 2nd International Conference on distributed Frameworks for multimedia applications 14-17 May 2006, Penang, Malaysia.

110. A clinical Study of Intrathecal Baclofen Using a Programmable Pump for Intractable Spasticity. D. Guillaume, A Van Haverberg, M. Vloeberghs, J. Vidal, G. Roste. Archives of Physical Medicine and Rehabilitation, American Academy of Physical Medicine & Rehabilitation. November 2005, vol. 86, No 11, 2165-2171.

111. Pitfalls in the laboratory investigation of suspected non-accidental head injury (NAHI) in infants: The need for a recognized protocol. J. Clayton, M. Vloeberghs. British Journal of Neurosurgery, August 2004, Vol. 18, Number 14.

112. A virtual reality surgery simulation of cutting and retraction in neurosurgery with force-feedback, Wang, P., Becker, A. A., Jones, I. A. , Glover, A.T., Benford, S. D., Greenhalgh, C. M. and Vloeberghs, M., J. Computer Methods & Programs in Biomedicine, accepted July 2006 (in press).

113. Computational mechanics in virtual reality: cutting and tumour interactions in a boundary element simulation of surgery on the brain. I.A. Jones, A.A. Becker, A.T. Glover, P. Wang, S.D. Benford, M. Vloeberghs, C.M. Greenhalgh. Applied Mechanics and Materials, Vol. 5-6 (2006), pp.55-62.

114. Virtual reality simulation of surgery with haptic feedback based on the boundary element method. P. Wang, A. Becker, I. Jones, A. Glover, S. Benford, C. Greenhalgh, M. Vloeberghs. J. Computers and Structures, Vol. 85, 331-339 (2007). 115. Virtual Neurosurgery; training for the future. M. Vloeberghs, T. Glover, S. Benford, A. Jones, A. Becker, P. Wang. British Journal of Neurosurgery, vol 21, No 3, p 262- 268, 7/2007.

116. The role of Intrathecal Baclofen in the management of primary and secondary dystonia in children. K. Woon, M. Tsegaye, M. Vloeberghs. British Journal of Neurosurgery, vol. 21, No 4, p 355-358, 8/2007.

117. Position of the Intrathecal Baclofen catheter in the spine for spasticity-Does it matter? G. Sivakumar, M. Tsegaye, M. Vloeberghs. FP12.7, XXXVII, Acta Neurochirurgica, The European Journal of Neurosurgery, Special edition. 9/ 2007.

118. Intrathecal Baclofen in children, a review of 160 implants and preliminary results of the randomised controlled trials. M. Vloeberghs. FP35.1, C, Acta Neurochirurgica, The European Journal of Neurosurgery, Special edition. 9/2007.

119. Placement of Intrathecal Baclofen pump catheters through posterior cervical approach in the paediatric population. G. Sivakumar, M. Vloeberghs. P24.08, CXCVII, Acta Neurochirurgica, The European Journal of Neurosurgery, Special edition, 9/ 2007.

120. Treatment of CNS tumours by targeted drug delivery: Intrathecal chemotherapy for brain tumours. Michael Vloeberghs, Richard Grundy , David Walker. ST-15, Neuro-Oncology, p.601, 10/2007.

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121. Intrathecal Chemotherapy delivered by a lumbar-thecal catheter in metastatic medulloblastoma: a case illustration. J. Clayton, M. Vloeberghs, T. Jaspan, D. Walker, D. MacArthur, R. Grundy. Acta Neurochirurgica, DOI 10.1007/s00701-008-1577-y, 2008. (on-line)

122. Intra Thecal Chemotherapy (ITC) for Central Nervous System Tumours. M. Vloeberghs, D. Walker, R. Grundy. Proceedings of the 2nd World Congress on Controversies in Neurology (CONY). Athens, Greece, October 23-26, 2008

123. A registration framework for preoperative CT to white light images. M. Gooroochurn, M. Ovinis, D. Keer, K. Baozza-Marouf, M. Vloeberghs. Proceedings of Medical Image Understanding and analysis, 2009, p. 184-188.

124. Consensus on the appropriate use of IntraThecal Baclofen (ITB) therapy in paediatric spasticity. European ITB working party, M. Vloeberghs Co author. European Journal of Paediatric Neurology, Vol. 14, Issue 1, p 19-28, January 2010.

125. Real-time surgical simulation for deformable soft tissue objects with a tumour using boundary element techniques. P. Wang, A. Becker, A. Jones, I. Glover, S. Benford, M. Vloeberghs. Journal of Physics, Conference series 181 (2009), Proceedings of the Seventh International Conference Modern Practice in Stress and Vibration Analysis, 8-10 Sep 2009, Cambridge.

126. Medulloblastoma in childhood, revisiting IntraThecal Chemotherapy in infants and children. S. Conroy, M. Garnett, M. Vloeberghs, R. Grundy, I. Craven, D.Walker. Cancer Chemotherapy Pharmacology, DOI10.1007/S00280-009-1127-1, Sept. 2009.

127. Intrathecal Baclofen therapy for spasticity of cerebral origin. Does the position of the intrathecal catheter matter. G. Sivakumar, Y. Yap, M, Tsegaye, M. Vloeberghs. Childís Nervous System, DOI 10.1007/s00381-010-1124-z, published on-line, Vol.26, No8, p 1097-1102, March 2010.

128. A methodology for design and appraisal of surgical robotic systems. M.D. O’Toole, K. Boazza-Marouf, D.Kerr, M. Gooroochurn, M. Vloeberghs. Robotica, vol. 28, pp. 297-310, Mar 2010.

129. Evaluation of robotics in surgery:clinical need and efficacy. Mobile Robotics: Solutions and Challenges-12th International conference on climbing and walking robots. M. O’Toole, K. Bouazza-MArouf, D. Kerr, M. Vloeberghs. World Scientific, 2009, pp. 233-241.

130. Analytical safety in autonomous surgical drilling. Mobile Robotics: Solutions and challenges - 12th International Conference on climbing and walking robots. M. O’Toole, K. Bouazza-Marouf, D. Kerr, M. Vloeberghs. World Scientific, 2009, pp.242-249.

131. Sliding contact mode force control for slip prevention in a robotic gripper. Mobile Robotics: Solutions and challenges-12th International conference on climbing and walking robots. M. O’Toole, K. Bouazza-Marouf, D. Kerr, M. Vloeberghs. World Scientific, 2009, pp. 327-334.

132. Insertion of intrathecal Baclofen implant by modified subfascial technique as to subcutaneous placement of implant in children. A. Ammar, G. Sivakumar, I. Ughratdar, M. Vloeberghs. Proceedings of EANS, 25-28 March Groningen. Abs 255.

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133. Intrathecal Baclofen catheter complications in children. A. Ammar, G. Sivakumar, I. Ughratdar, M. Vloeberghs. Proceedings of EANS, 25-28 March, Groningen. Abs 295.

134. Combined systemic and intra-CSF chemotherapy in the treatment of primary brain tumour leptomeningeal metastases. I. Jalloh, I Graham, J. Clayton, N. Whitehead, T. Jaspan, R. Grundy, D. Walker, M. Vloeberghs. Proceedings of Joint meeting of the Society for Neuro-oncology (SNO) and the American Association of Neurological Surgeons/ Congress of Neurological surgeons. Section on Tumours, Neuro-oncology 2009, 11(5):563-699.

135. Machine vision for the inspection of surgical tasks: Applications to robotic systems. M. Ovinis, D. Kerr, K. Bouazza-Marouf, M. Vloeberghs. Proceedings of the International conference on Machine Vision. Amsterdam, Netherlands, Vol. 70, pp.338-344, 2010.

136. Localisation of soft anatomical tissue landmarks of the head in CT images. M. Ovinis, D.Kerr, K. Bouazza-Marouf, M. Vloeberghs. Proceedings of the International conference on Machine Vision, Amsterdam, Netherlands, Vol. 70, pp. 752-758, 2010.

137. Status Dystonicus resembling the intrathecal Baclofen withdrawal syndrome: a case report and review of the literature. W. Muirhead, I. Jalloh, M. Vloeberghs. Medical Case Reports. Aug. 31; 4:294, 2010.

138. Three dimensional cerebrospinal fluid flow within the human central nervous system. L. Howden, D. Giddings, H. Power, M. Vloeberghs. American Mathematical Society. Discrete and Continuous Dynamical Systems Series B. Vol. 15, No 4, p957-969, June 2011.

139. Controlled study of the effects of continuous Intrathecal Baclofen infusion in non-ambulant children with cerebral palsy. R. Morton, N. Gray, M. Vloeberghs. Developmental Medicine and Child Neurology, 53: 2011, 736-741.doi:10.1111/j.1469-8749.201104009.x

140. Dynamic Facial Prosthesis for Sufferers of Facial Paralysis. Fergal Coulter*, Philip Breedon*, Michael Vloeberghs. *Nottingham Trent University, Australasian Medical Journal (AMJ) 2011,4,10, 555-562.

141. Artificial Facial Muscles. Philip Breedon*, Michael Vloeberghs. Request Article; Public Service Review, Central Government, 23, p82-83, 2011.

142. Complications of baclofen therapy, the 12 year Nottingham experience. H. Ingale, M. Vloeberghs, Childís Nervous System (2011) 27: 1751-1850.

143. Goals and outcomes for non-ambulant children receiving continuous infusion of intrathecal baclofen. N. Gray, R. Morton, M. Vloeberghs. Acc. European journal of Paediatric Neurology, 2012.

144. Intrathecal baclofen,therapy-How we do it. I. Ugrathar, M. Vloeberghs. Subm. J. Neurosurgery (US Paeds) 2012.

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145. Cervical implantation of intrathecalbaclofen pump catheters in children with severe scoliosis. I. Ugrathar, M. Vloeberghs. J. Neurosurgery (US Paeds) 2012.

146. Cervical catheter placement for intrathecal baclofen test dose: is it safe? S. Muquit, M. Vloeberghs. Childës Nervous System, Vool.28, Issue 6 (2012), p 919-922.

ELECTRONIC PUBLICATIONS

1. An Introduction to Neuroendoscopy Computer based tutorial system on CD-ROM M Vloeberghs, J Punt, M Terrett as 2nd Messenger in collaboration with Hypertech Multimedia and Johnson & Johnson, 1996

2. An Introduction to Intracranial Pressure Monitoring Computer based tutorial system on CD-ROM M Vloeberghs, J Punt, M Terrett as 2nd Messenger in collaboration with Hypertech Multimedia and Johnson & Johnson, 1997

3. Intrathecal Baclofen in the Treatment of Children with Cerebral Palsy. Interactive CD-ROM with patient and clinician information. M. Vloeberghs, Media Centre UoN, Medtronic, 2003

4. Injury in Microgravity. Interactive CD-ROM on the progress of Space Medicine. M. Vloeberghs 2004.

5. ECMT DVD, Drug delivery implant technique. M. Vloeberghs, 11/2004, sponsored by the European Centre for Medical training.

6. DVD, ITB in the management of spasticity in children. M. Vloeberghs. 2009

7. Deep Brain Stimulation with the NEX Frame. DVD. M. Vloeberghs. 2011. Sponsored by ECMT.

8. Selective Dorsal Rhizotomy. DVD. M. Vloeberghs. 2011. Sponsored by ECMT.

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PRESENTATIONS

1. Posttraumatic Rupture of the Thoracic Aorta. M Vloeberghs et al International Meeting on Cardiovascular Surgery, November 1986, Brussels

2. Blunt Thoracic Trauma M Duinslaeger, M Vloeberghs et al International Trauma Conference, September 1987, Bali,

3. Hoffmans External Fixator in 34 Intra-Articular Wrist Fractures M Vloeberghs et al International Conference of Orthopaedics, September 1988, Prague

4. Symptomatic Multilevel Upper Lumbar Disc Herniations M Vloeberghs et al Belgian Society for Neurosurgery, March 1989, Leuven

5. Les Voies d`Abord du Troisieme Ventricule J Noterman, M Vloeberghs Inter-University Seminar on Neurosurgery, April 1989, Brussels

6. Behandeling van de Polsfractuur Door Schuine Kirschner Verpenning M Vloeberghs et al Belgian AO Symposium, June 1989, Leuven

7. Externe Fixatie en Intra-Articulaire Comminutieve Polsfracturen E Verhaven, M Vloeberghs Orthopedica Nostra Quotidiana 4th SOBCOT Course, November 1989, Liege

8. A Propos d`un Cas de Syndrome de Gardner J Noterman, M Vloeberghs Belgian Society for Neurosurgery, March 1990, Brussels

9. Het Maligne Schwannoom van de Plexus Brachialis. M Vloeberghs et al Belgian Society for Neurosurgery, March 1990, Brussels 10. Solitair Intramedullair Schwannoom P Herregodts, M Vloeberghs Belgian Society for Neurosurgery, March 1990, Brussels

11. Primary Arachnoiditis Mimicking a Spinal Cord Tumor. M Vloeberghs et al 41 Jahrestagung der Deutschen Gesellschaft fur Neurochirurgie, May 1990, Dusseldorf

12. Spina Bifida en Dysraphisme M Vloeberghs Seminaria voor Kindergeneeskunde, October 1990, Brussels

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13. Interleukine Secretie in het Centraal Zenuwstelsel. P Herregodts, M Vloeberghs Belgian Society for Neurosurgery, March 1991, Brussels

14. Subarachnoidale Cystes M Vloeberghs Clinical Sessions in Paediatrics, December 1991, Brussels

15. Masse Nasale chez un Nouveau-Ne M Vloeberghs et al La Reunion Neurochirurgicale de Peyronne, March 1991, Peyronne, France

16. Pituitary Adenoma, the Complications of Transsphenoidal Resection M Vloeberghs et al BVNV Symposium, April 1991, Brussels

17. Externe Drainage bij Prematuren met een Intraventriculaire Bloeding M Vloeberghs et al Inter-University Seminar on Neurosurgery, December 1991, Brussels

18. Ongebruikelijke Evolutie van een Maligne Schwannoom van de Plexus Brachailis M Vloeberghs et al Belgian Society for Neurosurgery, March 1992, Brussels

19. Acute Management of Posthaemorrhagic Hydrocephalus in the Preterm Infant M Vloeberghs et al International Society for Paediatric Neurosurgery, June 1992, Prague

20. The Value of Stereotactic Surgery in Children D Jellinek, M Vloeberghs et al Society of British Neurological Surgeons, May 1993, Nottingham

21. The Management of Multifocal PNET M Vloeberghs, J Punt Medulloblastoma 1993, June 1993, Marseilles

22. Stereotactic Surgery in Paediatric Brain Tumour D Jellinek, M Vloeberghs British Neuro-Oncology Group, June 1993, Birmingham

23. Multifocal PNET J Punt, M Vloeberghs British Neuro-Oncology Meeting, June 1993, Birmingham

24. Pre-Operative Chemotherapy in Medulloblastoma in Childhood M Vloeberghs et al The Belgian Paediatric Haematology and Oncology Group, September 1993, Genval, Belgium

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25. The Use of Stereotactic Surgery in Children M Vloeberghs et al International Society For Paediatric Neurosurgery, October 1993, Phoenix, Arizona

26. Multidisciplinaire Benadering van Schedelbasis Fracturen M Vloeberghs et al Royal Belgian Society for Maxillofacial Surgery, November 1993, Brussels

27. Multidisciplinair Management van Hersentumoren. Stereotactische Indicaties bij Kinderen M Vloeberghs et al Seminaria voor Kindergeneeskunde, February 1994, Brussels

28. Instabiele Letsels ter Hoogte van de Craniocervicale Overgang N De Klippel, M Vloeberghs Vlaamse Vereniging voor Zenuwartsen, April 1994, Gent, Belgium

29. Transorale Toegang tot de Hoge Cervicale Zuil; Twee Gevallen M Vloeberghs et al Belgian Society for Neurosurgery, March 1994, Brussels

30. Etude IRM des Recidives de Hernie Discale vs Fibrose: Solution Finale au Probleme? J D`Haens, M Vloeberghs Controverses et Avances en Pathologie Rachidienne, June 1994, Lille

31. Traitement Chirurgical par Voie Anterieure dans les Compressions Radiculo-Medullaires Cervicales díOrigine Degeneratieve J D`Haens, JVangeneugden, M Vloeberghs et al Controverses et Avances en Pathologie Rachidienne, June 1994, Lille

32. Shunt Insertion and the Neuroguide Kit M Vloeberghs Combined Codman Salesforce Meeting, January 1995, Antwerp

33. Third Ventriculostomy Using the ëAir Bubbleí Technique M Vloeberghs et al Annual Meeting of the Belgian Society for Neurosurgery, March 1995, Leuven

34. Endoscopic Retrieval of a Blocked Ventricular Catheter and Endoscopic Catheter Reinsertion M Vloeberghs et al Annual Meeting of the Belgian Society for Neurosurgery, March 1995, Leuven

35. Neuroendoscopy: ëVoyage to the Centre of the BrainÇ Joint Lecture: J Punt, M Vloeberghs, E Couch National Theatre Nurses Symposium III, March 1995, Birmingham

36. A Computer Assisted Teaching Device for Neuroendoscopy M Vloeberghs, J Punt, Hypertech Multimedia Belgian Society for Neurosurgery, March 1996, Brussels

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37. Surgery for Occult Dysraphism M Vloeberghs Symposium for Paediatric Uro-Nephrology, March 1996, Leicester

38. Neuroendoscopy M Vloeberghs ASBAH Residential Training Weekend, April 1996, Nottingham

39. Neuroendoscopy in the management of childhood hydrocephalus J Punt, M Vloeberghs Society of British Neurological Surgeons, April 1996, Preston

40. Neuroendoscopy in Children M Vloeberghs, J Punt Trent Regional Paediatric Society Meeting, May 1996, Lincoln

41. Spina Bifida and Hydrocephalus Current Treatment M Vloeberghs ASBAH Family Weekend, May 1996, Northampton

42. A Computer Assisted Learning Program for Neuroendoscopy M Vloeberghs, J Punt, M Terrett International Society for Paediatric Neurosurgery, July 1996, Ottawa, Canada

43. Computer Assisted Learning in Neuroendoscopy M Vloeberghs, J Punt, M Terrett Joint Meeting Society of British Neurological Surgeons and DGN, September 1996, Hannover, Germany

44. Neuroendoscopy M Vloeberghs Spina Bifida and Hydrocephalus in Uganda, September 1996, Kampala

45. A Computer Assisted Learning System for Neuroendoscopy J Punt, M Vloeberghs European Society for Paediatric Neurosurgery, September 1996, Rome

46. A Computer Assisted Learning System for Neuroendoscopy J Punt, M Vloeberghs Third International Meeting on Minimally Invasive and Endoscopic Surgery, October 1996, Marburg

47. The Role of Neuroendoscopy in the Management of Shunt Complications J Punt, M Vloeberghs Trent Regional Paediatric Society, October 1996, Nottingham

48. Hydrocephalus, Once a Shunt Always a Shunt? M Vloeberghs 30 Years On, Making the Most of Life. ASBAH Study Day, November 1996, Oldham

49. A Neuroendoscopic Approach to Liliequist`s Membrane, A Video Presentation N Buxton, M Vloeberghs, J Punt Scientific Meeting British Association of Clinical Anatomists, December 1996, London

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50. Neuroendoscopy in Shunt Complications M Vloeberghs, J Punt, C Mallucci British Paediatric Neurology Association Meeting, January 1997, Oxford

51. Should Shunts be Revised When Endoscopic Third Ventriculostomy is Available? C Mallucci, M Vloeberghs, J Punt Joint meeting of the Society of British Neurological Surgeons and the Neurosurgical Society of America, April 1997, Cambridge

52. Third Ventriculostomy in Shunt Complications C Mallucci, M Vloeberghs, J Punt Complex Hydrocephalus and Hydrocephalus Complications, April 1997, Assisi

53. Neuroendoscopy in the Management of Hydrocephalus M Vloeberghs, J Punt, C Mallucci Bi-Annual Meeting of the European Society for Paediatric Surgery, May 1997, Madrid

54. Modern Management of Hydrocephalus by Neuroendoscopy M Vloeberghs Current Approaches to Spina Bifida and Hydrocephalus, May 1997, Birmingham

55. Neuroendoscopic Third Ventriculostomy; The First Line Treatment for Blocked Ventriculoperitoneal Shunts? C Mallucci, M Vloeberghs, J Punt Trent Regional Paediatric Society, May 1997, Derby

56. Neuroendoscopic Third Ventriculostomy in Hydrocephalus C Mallucci, M Vloeberghs, J Punt Consensus Conference on Hydrocephalus, June 1997, Assisi

57. Neuroendoscopic Third Ventriculostomy as an Alternative for Shunt Revision C Mallucci, M Vloeberghs, J Punt Society for Research into Hydrocephalus and Spina Bifida, July 1997, Manchester

58. A Rapid Prototype Model of the Human Ventricular System M Vloeberghs, F Hatfield, F Daemi, P Dickens Computer Integrated Surgery, September 1997, Linz, Austria

59. A Virtual Reality Model of the Human Ventricular System M Vloeberghs, F Hatfield, F Daemi 1st International Conference on Computer Integrated Surgery, September 1997, Linz, Austria

60. Computer Assisted Learning Packages in Neurosurgery M Vloeberghs, M Terrett, J Punt Computer Integrated Surgery, September 1997, Linz, Austria

61. Liliequistís Membrane: A Re-Examination of its Importance N Buxton, M Vloeberghs, J Punt 4th European Association of Clinical Anatomy Congress, September 1997, Lille, France

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62. Neuroendoscopic Third Ventriculostomy; The First Line Treatment for Blocked Shunts C Mallucci, M Vloeberghs, J Punt International Society of Paediatric Neurosurgery XXV, September 1997, Verona

63. Neuroendoscopic Management of Shunt Complications M Vloeberghs, C Mallucci, J Punt International Symposium on Spina Bifida and Hydrocephalus, September 1997, Kobe, Japan

64. Intrathecal Baclofen. Is it as Good as it Seems? M Vloeberghs Invited lecture at the Ronnie Mackeith Meeting, Royal Society of Medicine, October 1997, London

65. The Management of Hydrocephalus by NTV M Vloeberghs Scientific Meeting of the Belgian Society for Neurosurgery, March 1998, Brussels

66. Primary Neuroendoscopic Third Ventriculostomy for Hydrocephalus N Buxton, C Mallucci, D Macarthur, I Robertson, M Vloeberghs, J Punt Society of British Neurological Surgeons, April 1998, Sheffield

67. Primary Neuroendoscopic Third Ventriculostomy in Patients Less than One Year Old N Buxton, D Macarthur, C Mallucci, J Punt, M Vloeberghs Society for Research into Spina Bifida and Hydrocephalus, June 1998, Genoa

68. The Role of Neuroendoscopy in the Management of Brain Tumours D Macarthur, N Buxton, M Vloeberghs, J Punt British Neuro-Oncology Group, July 1998, Kent

69. Automatic Delineation and 3-D Visualisation of the Human Ventricular System Using Probabilistic Neural Networks F Hatfield, J Demeshki, F Daemi, M Vloeberghs International Conference on Electronic Image Capture and Publishing, May 1998, Zurich

70. Neuroendoscopic Third Ventriculostomy in the Under Ones M Vloeberghs, J Punt Endoscope Assisted Neurosurgery, June 1998, Frankfurt

71. A Virtual Reality Model of the Human Ventricular System M Vloeberghs, F Daemi, J Demeshki, F Hatfield Endoscope Assisted Neurosurgery, June 1998, Frankfurt

72. Neuroendoscopy in the Management of Childhood Hydrocephalus M Vloeberghs Spina Bifida Association of America, June 1998, Washington DC

73. The Role of Neuroendoscopy in the Management of Brain Tumours D Macarthur, N Buxton, J Punt, M Vloeberghs European Association for Neurooncology (EANO) III, September 1998, Versailles

74. The Role of Neuroendoscopy in the Management of Childhood Brain Tumours D Macarthur, N Buxton, J Punt, M Vloeberghs Societe Internationale díOncologie Paediatrique (SIOP) XXX, October 1998, Yokohama, Japan

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75. The Use of Transendoscopic Doppler Ultrasound as Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Belgische Wetenschappelijke Vereniging voor Neurochirurgie, March 1999, Brussels

76. A Digital Healthcare Project at the University of Nottingham M Vloeberghs, F Hatfield, F Daemi Hospital without walls, March 1999, London

77. Neuroendoscopic Third Ventriculostomies for Hydrocephalus in Adults N Buxton, M Vloeberghs et al Society of British Neurological Surgeons, April 1999, Leeds

78. Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Society for Research into Hydrocephalus and Spina Bifida, June 1999, Sheffield

79. The Use of Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs Society of British Neurological Surgeons, September 1999, Cork

80. Third Ventricle Width Variations in Patients Undergoing Primary and Secondary NTV S Thomson, M Cartmill, M Vloeberghs Society of British Neurological Surgeons, September 1999, Cork

81. The Financial Implications of Neuroendoscopic Third Ventriculostomy M Vloeberghs, M Cartmill World Conference on Paediatric Neurosurgery, June 1999, Martinique

82. Neuroendoscopic third ventriculostomy in the premature population. M Vloeberghs, M Cartmill World Conference on Paediatric Neurosurgery, June 1999, Martinique

83. Statistical Multivariate Analysis of Neuroendoscopic Third Ventriculostomy in the Management of Childhood Hydrocephalus M Vloeberghs, M Cartmill Society of British Neurological Surgeons, April 2000, Glasgow

84. Cerebrospinal Fluid dynamics in the Aqueduct of Sylvius A Aroussi, M Zainy, M Vloeberghs 9th International Symposium of Flow Visualisation, August 2000, Edinburgh

85. Intrathecal Baclofen for the Management of Spasticity in Children with Cerebral Palsy within the United Kingdom M Vloeberghs, M Cartmill, S Bassi. International Society for Paediatric Neurosurgery, October 2000, Istanbul

86. A Parametric Study of Cerebrospinal Fluid Flow in the Human Ventricular System M Vloeberghs, J Towe, M Zainy, M Cartmill, A Aroussi. International Society for Paediatric Neurosurgery, October 2000, Istanbul

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87. The Use of Transendoscopic Doppler Ultrasound as a Safety Enhancing Measure During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs International Society for Paediatric Neurosurgery, October 2000, Istanbul

88. The Use of Intrathecal Baclofen in the Management of Spasticity in Children with Cerebral Palsy M Vloeberghs, M Cartmill, S Bassi British Neurosurgical Research Group, March 2001, Sheffield

89. Multivariate Statistical Analysis to Predict Outcome in Neuroendoscopic Third Ventriculostomies M Cartmill, M Vloeberghs British Neurosurgery Research Group, March 2001, Sheffield

90. A Parametric Study of the Cerebrospinal Fluid Flow in the Human Ventricular System M Vloeberghs, M Zainy, A Aroussi, M Cartmill British Neurosurgical Research Group, March 2001, Sheffield

91. Intrathecal Baclofen in the UK M Vloeberghs Society of British Neurological Surgeons, April 2001, Newcastle

92. Animal model for foetal hydrocephalus and intra-uterine cerebral ventriculoscopy; preliminary results. B. Dekeersmaker, M. Vloeberghs, Y. Ville. Research & Developments in Foetal Medicine. 31/8/2001, London, Feto-Maternal Medicine Foundation.

93. Animal model for foetal hydrocephalus and intra-uterine cerebral ventriculoscopy; preliminary results. B. Dekeersmaker, M. Vloeberghs, Y. Ville. The international fetal Medicine and Surgery Society. 2/10/2001. Krugerpark, South Africa.

94. Animal model for foetal hydrocephalus and intra-uterine cerebral ventriculoscopy; preliminary results. B. Dekeersmaker, M. Vloeberghs, Y. Ville. Society for Maternal & Fetal Medicine USA. Accepted.

95 A parametric study of cerebrospinal fluid flow in the human ventricular system. M. Vloeberghs, A. Aroussi, M. Zainy, M. Cartmill. ISPN, Istanbul 2000

96. A virtual reality model of the human ventricular system. A. Aroussi, M. Vloeberghs, M. Zainy. 9th Millennium International Symposium on Flow visualisation, Edinburgh 2000,

97. Cerebrospinal Fluid Dynamics. A. Aroussi, M. Zainy, M. Vloeberghs 9th Millennium International Symposium on Flow visualisation, Edinburgh 2000,

98. Experimental Hydrocephalus in sheep: a validation experiment for neuroendoscopy. M. Vloeberghs, B. Dekeermaecker, Y. Ville ISPN, Sept 2003, Monaco

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99. Aspects of the treatment of spasticity due to cerebral palsy in children with Intrathecal Baclofen. M. Vloeberghs, J. Fitzgerald, M. Tsegaye, M. Cartmill ISPN, Sept 2003, Monaco

100. Injury in Microgravity. M. Vloeberghs. UK Space Medicine Day, Leicester, 11 August 2004.

101. Injury in Microgravity. M. Vloeberghs. Space Research Centre, University of Leicester, 11/2004.

102. Surgical Simulation, Virtual Neurosurgery. M. Vloeberghs, Brain Mapping and Intraoperative Surgical Planning, Clermont-Ferrand, France, Sept 5-8 2006.

103. Intrathecal Baclofen treatmentfor spasticityin children with cerebral palsy: a series of 104 cases. M. Tsegaye, M. Vloeberghs. Neurochirurgie und Neurorehabilitation im Dialog, Bochum, GER, Nov. 9-11, 2006

104. Baclofen infusion pumps in childhood CP. M. Vloeberghs. British society of Rehabilitation Medicine Winter Meeting. Loughborough. Nov. 13-14, 2006

105. Intrathecal Baclofen in Paediatric Movement Disorders. M. Vloeberghs. Neurorehabilitation Pediatrique: Regards Croises. Geneva. Nov. 30, 2006

106. Position of the Intrathecal Baclofen catheter in the spine for spasticity-Does it matter? G. Sivakumar, M. Tsegaye, M. Vloeberghs. EANS Glasgow 9/ 2007.

107. Intrathecal Baclofen in children, a review of 160 implants and preliminary results of the randomised controlled trials. M. Vloeberghs. EANS Glasgow 2007

108. Intra Thecal Chemotherapy in Central Nervous System Tumours. M. Vloeberghs. CONY, Athens, Greece, 26 October 2008.

109. ITB and DBS in Children. M. Vloeberghs. Invasive treatment of spasticity. Leicester. 19/1/2008.

110. Legends in ITB, catheter position & Withdrawal syndrome. M. Vloeberghs. IDD meeting Geneva. 13/12/2008.

111. Intra Thecal Chemotherapy and CSF flow. M. Vloeberghs. IDD meeting Geneva. 13/12/2008.

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MEDIA PRESENTATIONS

1. Wel Jong Niet Gek ( Road Traffic Accident Prevention Campaign) M Vloeberghs Radio interview: BRT Studio Brussel Broadcasted 17/04/92 18h

2. Wel Jong Niet Gek (Road Traffic Accident Prevention Campaign) M Vloeberghs TV interview: BRT KIJK UIT Broadcasted 24/04/92 20h30

3. ITB in “Field’s” disease. M. Vloeberghs. Japan TV. 2007

REQUEST ARTICLES

1. The effectiveness of Intrathecal Baclofen in the Management of Patients with Severe Spasticity. The SCHARR Report. Co-author, M. Vloeberghs. 6/2000

2. Intrathecal Baclofen in the management of spasticity due to cerebral palsy in children. M. Vloeberghs Requested by The Journal of the British Association of Bobath Trained Therapists. 3/2002

3. Intrathecal Baclofen in the management of spasticity in children. M. Vloeberghs Requested by Advances in Clinical Neuroscience & Rehabilitation. 6/2002

4. Management of Spasticity in children with cerebral palsy. M. Vloeberghs, R. Keetley, R. Morton. Requested by ACNR, vol 4 no 1, March 2004.

5. Intrathecal baclofen in spasticity of cerebral origin. M. Vloeberghs. Requested by Pediatric Rehabilitation, in Press Dec 2004,

6. Decision making in paediatric brain tumours a neurosurgical perspective. M. Vloeberghs. Current Paediatrics, Vol 15, Issue 5, p 406-411, Oct 2005.

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POSTERS

1. Where Does The Cerebrospinal Fluid Flow After Neuroendoscopic Third Ventriculostomy? M Cartmill, M Vloeberghs World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

2. The Use of Transendoscopic Doppler Ultrasound During Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

3. Liliequistís Membrane in Neuroendoscopic Surgery M Cartmill, N Buxton, M Vloeberghs World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

4. Variations in Third Ventricle Width in Patients Undergoing Neuroendoscopic Third Ventriculostomies M Cartmill, S Thomson, M Vloeberghs World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

5. The Financial Implications of Neuroendoscopic Third Ventriculostomy M Vloeberghs, M Cartmill, V Gonugunta World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

6. Results of Neuroendoscopic Third Ventriculostomy in the Management of Childhood Hydrocephalus M Vloeberghs, M Cartmill World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

7. Repeat Neuroendoscopic Third Ventriculostomies M Vloeberghs, M Cartmill World Conference on Paediatric Neurosurgery 2000, November 1999, Martinique

8. Cerebrospinal Fluid Redistribution Following Neuroendoscopic Third Ventriculostomy M Cartmill, M Vloeberghs European Society For Paediatric Neurosurgery, June 2000, Graz, Austria

9. Neuroendoscopic Third Ventriculostomies for Failed Shunts N Buxton, M Vloeberghs, M Cartmill, J Punt, I Robertson American Association of Neurological Surgeons, April 2001, Toronto

10. A Parametric Study of the Cerebrospinal Fluid Flow in the Human Ventricular System M Vloeberghs, M Zainy, A Aroussi, M Cartmill British Neurosurgical Research Group, March 2001, Sheffield

11. The Use of Intrathecal Baclofen in the Management of Spasticity in Children with Cerebral Palsy M Vloeberghs, M Cartmill, S Bassi Society of British Neurological Surgeons, April 2001, Newcastle

12. Risk Management in Space Medicine and healthcare. M. Vloeberghs UK Space Medicine day, Leicester 11 August 2004.

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13. D.Walker, S.Ammourah, A.Aroussi, M.Garnett, D.Giddings, L.Howden, H.Power, & M.Vloeberghs Physical and numerical modelling cerebrospinal fluid behaviour for drug delivery to the lepto-meninges. 6th Meeting of the European Association for Neuro-Oncology, Edinburgh 4/2005.

14. Treatment of CNS Tumours by targeted drug delivery: Intrathecal chemotherapy for brain tumours. M. Vloeberghs. SNO, Texas, Nov. 2007

REVIEWS AND EDITORIAL WORK

Journal of Neurology, Neurosurgery and Psychiatry: Clinical features of third ventriculostomy failures classified by fenestration patency. T Fukuhara. 8/2000

Journal of Neurology, Neurosurgery and Psychiatry: Virtual MRI endoscopy: detection of anomalies of the ventricular anatomy and it’s possible role as a presurgery planning tool. V Rohde 2/2001.

Child’s Nervous System: Post Haemorrhagic Hydrocephalus in Preterm Infants. A. Renprecht 3/2001

Abstract review committee for the Society of British Neurological Surgeons.September 2001 meeting.

Pediatric Surgery: Effects of Selective Dorsal Rhizotomy in Children with Cerebral Palsy.Van Schie P. et al. 6/2001.

Journal of Neurology Neurosurgery and Psychiatry: To screen or not to screen. Another familial occurrence of colloid cysts of the third ventricle.RS Katsuri. 6/2001.

Child’s Nervous System: Subdural Haematoma and Non-Accidental Head Injury in Children: A. Hoskote, P. Richards, P. Anslow. 10/2001

Paediatric Neurosurgery: Hockley et al, 2002, book review requested by Elseviers Scientific.

Child’s Nervous System: Endoscopy vs Shunt for the treatment of hydrocephalus. M. Fritsch 8/2002

Child’s Nervous System: The treatment of large supratentorial arachnoid cysts in infants. S. Baldari. 8/2002

British Journal of Neurosurgery: Achondroplasia: a cause of increasing head circumference in a neonate. AM Groves. BJN/2002/797. 1/2003

I am currently a regular reviewer for the BJN, Childís Nervous System. ( See portfolio)

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TEACHING

General Teaching I take an active role in teaching medical students, nurses and physiotherapists within the department. I am also involved in the supervision and teaching of neurosurgical and general surgical trainees both nationally and internationally.

I am a lecturer on the paediatric specialist registrarsÇ training program following an approach by the Child Health Department of the University of Leicester.

As part of my inter-specialty training I supervise and teach basic physiological concepts to post-graduate engineers in the framework of my CSF flow research projects.

Computer Assisted Learning

As part of my Information Technology interest I have produced two CD-ROMís on neurosurgical subjects: neuroendoscopy and intracranial pressure monitoring. These are used for both undergraduate and postgraduate education.

I have also developed a patients, web-site which aims to inform and teach interested parties on the technique and outcome of Intrathecal Baclofen treatment.

College Tutor in Neuroendoscopy

After having been part of the original Neuroendoscopy user group set up by Johnson & Johnson, training courses were organised in the UK and Belgium. Two courses were held in Belgium at the Vrije Universiteit Brussel in 1994 and two courses were held at the University of Nottingham. When I was appointed to the University of Nottingham, a request came from the Royal College of Surgeons of England to organise regular courses in London. These courses are under my direction and have taken place twice a year at the Raven Workshop of the Royal College of Surgeons since 1996. The course aims to teach Neuroendoscopic Third Ventriculostomy as this method is the first line treatment for hydrocephalus. This course involves lectures, practical demonstrations and group tutorials. An advanced course is planned utilising endoscopy in the subarachnoid space.

International Education

Because of my interest in international child health I have established a neuroendoscopy training base in Poland. The first training session was held in Gorzow in 1997. These training sessions include on-site operating with the local consultants. I currently operate one or two weeks in Poland on a voluntary basis.

A complete neuroendoscopy centre with a dedicated theatre has been set up in Gdansk in collaboration with Dr J Rogon, paediatric surgeon and local sponsors. This activity is ongoing and regular consultations between me and the Gdansk base are held over the Internet. Courses are now held in Gorzow, Wroclav and Gdansk. Further courses were held in the sultanate of Oman in 2002 and an update course in 12/2004.I have established a Neuroendoscopy base in Bratislava, Slovakia, with Dr F. Horn, 11/2004.The latest course was held in Hyderabad, Pakistan, 6/2007.

I am involved with the International Federation for Hydrocephalus and Spina Bifida (IFHSB) and have been part of several international fact finding missions (Uganda, Eastern Europe). Tanzania and Poland are the next countries to be targeted by the IFHSB.

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ITB international: As NUH now has the largest European-world activity in ITB in children I was asked to either lecture or set up ITB centres in Europe and the Middle East: Geneva Switzerland, Beirut Lebanon, Nicosia Cyprus.

The same teachign activity is happening for SDR as this technique with single level approach is proving to be of low-cost and an effective treatment for spasticity in all GMFCS group, including GMFCS 4-5 also known as spastic quadriplegic children with severe spasticity.

Lecturer on the Foetal Medicine Course

I lecture on the annual International Course in London for the Diploma in Foetal Medicine: The Management of Neural Tube Defects.

This runs under the auspices of the International Society of Ultrasound in Obstetrics and Gynaecology and the World Association of Perinatal Medicine.

Baclofen Day

As part of my audit activity and also as a way to educate and communicate with parents, patients and parties interested in Intrathecal Baclofen treatment, I organise gatherings of these diverse groups. The meetings are held at the Jubilee Campus, in Nottingham and consist of short presentations by ancillary services e.g. nurses, solicitors, physiotherapists and parents. I present the current results of our group to the parents and all interested parties. This effort fits in the framework of the new NHS where direct presentations to the public regarding results and complications of a specific procedure become important. These meetings have been a great success with an ever increasing number of attendants e.g. patients, parents, carers, in-house staff etc. The meetings have generated significant media attention in both local and national press, radio and TV.

In a way these meetings have set a precedent, where a surgeon presents his results to the public. These results not only present the total numbers treated but also discuss the adverse events.

The question and answer session at the close of the meeting aims to get return comments from the parents and patients to improve the care, and management of patients at all levels.

A recent advance is the creation of a patient website on which all results will be posted and updated. www.baclofen.info

ECMT courses:

Because of my expertise in implanting drug delivery systems, the European Continuing Medical Training approached me to conduct courses on the surgical technique. A first course is held in Nottingham, 13/2004, with participants from around Europe, who wish to establish a Baclofen service in their country. The course is based on lectures; interactive presentations and a hands-on section on sheep bellies, to simulate the subfascial implant technique.

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Invited Lectures:

Clinical Use of eth Intra Thecal Baclofen Pump.M. VloeberghsSeptember 1, 2004, Tadworth.

Surgical Implant Procedure in the Paediatric Patient and Update on the UK CP ITB Study.M. VloeberghsOctober 14 2004, Birmingham. ITB Update Meeting.

Intrathecal Baclofen in Children.M. Vloeberghs.3 December 2004, Sultanate of Oman. 9th Paediatric Neurosurgery Update.

Neuroendoscopy in the management of hydrocephalus in children.M. Vloeberghs3 December 2004, Sultanate of Oman. 9th Paediatric Neurosurgery Update.

Neuroendoscopy for childhood hydrocephalus.M. Vloeberghs18 November 2004, Bratislava. 3rd Days of Paediatric Surgery.

Intrathecal Baclofen in Children.M. Vloeberghs18 November 2004, Bratislava. 3rd Days of Paediatric Surgery.

The results of Intrathecal Baclofen in children.M. VloeberghsAustria, 9-1 June 2006. ITB user group

Cerebral palsy and ITB.M. VloeberghsAustria, 9-11 June 2006

ITB in cerebral palsyM. VloeberghsBeirut, 2007

ITB in cerebral palsyM. VloeberghsCyprus, 2007

ITB in cerebral palsyM. VloeberghsDublin, 2008

ITB in cerebral palsyM. VloeberghsZurich, 2008

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CURRENT PRACTICE

Clinical Practice

My current practice involves the running of a comprehensive paediatric neurosurgery practice offering the complete range of paediatric neurosurgical procedures. These include the management of hydrocephalus, head injury, dysraphism, neuro-oncology, craniofacial abnormalities, spasticity and both resective and non-resective epilepsy surgery. As is typical for paediatric neurosurgery, 50% of my practice lies with management of hydrocephalus. The remainder of the practice is fairly evenly distributed.

My special interest is neuroendoscopy. This has become the cornerstone for the treatment of hydrocephalus at QMC. My other interests are neonatal and in-utero neurosurgery. The latter is performed in collaboration with Professor Nicolaides, Kings College, London.

Spasticity Secondary to Cerebral Palsy

From the start of my appointment at QMC, I have laboured to promote the neurosurgical treatment of spasticity in children. The main focus of the treatment is the use of continuous intrathecal baclofen (ITB). The first implant was ultimately done in October 1998 and since then I do approximately two implants per month at QMC. The baclofen programme took a fair amount of negotiating with Local and out of area Health Authorities and has led to the SCHARR report on effectiveness of ITB, of which I am a co-author. Clinical outcome studies are a main part of the programme, which is under constant review by both the Health Authorities and myself.

Selective Dorsal Rhizotomy using a single level approach is gaining interest. I learned the technique from Dr P. Steinbock in Vancouver and am routinely doing SDR in spastic children at NUH.

Traditionally SDR was reserved for mobile or struggling mobile children (aka GMFCS 2-3 group). I now have substantial experience and evidence that SDR is an effective treatment in severely spastic children with quadriplegia (aka GMFCS 4-5).In my current experience the results are equivocal to those of IntraThecal Baclofen (ITB) in that patient group. A formal study is in progress.

ITB is a very effective treatment for severe spasticity but has “overheads” e.g. risk of infection, catheter problems, perpetual maintenance and replacement. the size of et pump is often an issieu for the patients/ parents. I did some ITB in mobile children (13 in total) but found the result to be in line with the non- mobile children e.g. fair spasticity relief but little effect on gait.

SDR is proving to be vey effective for mobile children, surpassing the results of ITB, this to the point that children where the pump is due for replacement are opting for SDR instead.

SDR has no overheads and a low complication rate, if any.

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Neurocybernetics

Branching off from my experience with drug delivery systems, I gained experience in the management of chronic pain via morphine or methadone infusion. In selected cases rhizotomy or dorsal column stimulators can be used. Further implamts consist of vagus nerve stimulators (VNS) in the treatment of intractable epilepsy. The VNS have now been formally accepted as a treatment for non-lesional epilepsy in children and a VNS program under my initiative is starting at Queens Medical Centre.

Deep brain stimulation for dystonia is to be forwarded in the near future and is to expand into the adult age range. All these programs are subject to permanent audit, update and are part of a clinical outcome study.

My future ambition is to create a Neurocybernetic unit at Queens Medical Centre, which will make use of the state of the

Telemedicine

As a further diversification of my interest in applications of technology in medicine I have started a telemedical program at QMC in collaboration with Nottingham Telephones and Tandberg Telecommunication. The network links our neurosurgical theatres to the neurosurgical library for supervision and teaching purposes.

A further link is now established between the operating theatres and the neuropathology department. This allows real time discussion of intraoperative sampling and in return direct view and discussion of a pathology specimen between neurosurgeon and pathologist. Further expansion of the teaching limb is expected in the near future to more remote sites.

Complementary Medicine

I have undertaken a training course in acupuncture to gain insight into complementary medicine. I regularly treat patients on a voluntary basis for the common indications of complementary therapy e.g. pain management, stress, substance abuse and various visceral indications.

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GRANTS

Recipient of the “Horlait Dapsens” Specialisation Scholarship: Value £10,000, 1992.The Intraventricular Haemorrhage in the Preterm Infant

Awarded research grant from the University of Nottingham. Half cost studentship with Dr Aroussi, Department of Mechanical Engineering: Value £15,000, 1997. A Fluid Hydrodynamics Model of the Human Ventricular System

Grant from the special trustees of Queens Medical Centre: £10,000, 2000.Telemedicine network.

EPSRC grant in partnership with Mechanical Engineering and Computer Science: value £300000, 2002. Simulation of brain surgery.

Welcome VIP award, £25000, held jointly with Mechanical Engineering, salary for RA, Dr Don Giddings, Simulation of CSF circulation, 11/2004.

EPSRC Follow-on fund, £35000 for continuation of the Virtual Brain Surgery project, 1/2005.

UK Gov. Innovation Fellowship, £ 15000, Virtual Brain Surgery, 6/2005.

Lachesis grant, £ 13000, market research for Virtual Brain Surgery, 1/ 2006.

NiHR grant of £500000 in collaboration with NTU, Dr Phil Breedon, First for Stroke, conpletion of an avatar rehabilitation system for facial paresis-paralysis. 2013

INDUSTRIAL SPONSORSHIP

In-kind Sponsorship:

1. Video equipment for neuroendoscopy via the Storz endoscopy firm: £10,000.2. Neuroendoscopes for continuation of the clinical practice: £12,000.3. Laptop for programming of, Medtronic, Synchromed drug delivery pumps: £6000.4. Laptop for programming the Cyberonics, Vagus Nerve Stimulator: £6000.5. Console for intraoperative Ultrasound Doppler: £50,000.6. Intraoperative Ultrasound Doppler Wires: £10,000.7. Telemedical communication consoles with appropriate wiring via intranet, including labour: £30,000.8. ERBE diathermy console as complement to the first UK use of the ERBE bipolar endoscopic electrode + 5 electrodes: £15000.

Industrial Grant:

Medtronic for interest in the fluid hydrodynamics program in partnership with Dr Aroussi, Mechanical Engineering, value £10000.

Industrial Donation or appointing a research physiotherapist, Medtronic: £50.000 over 3 years. + 10000 funding for expansion of the ITB RCT based in Nottingham.

Industrial donation by Medtronic, £ 50000, for continuation of RCT in Nottingham.

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OBJECTIVES

I intend to continue to hold the delicate balance between demanding clinical work and research. I hope to increase my generic research activity and obtain a track record in original technological applications in medicine.

INTERESTS

I was a keen rally driver as a junior doctor culminating in competing in the Trans-Algerian Desert Rally in 1986. Unfortunately my rally career was cut short following a high-speed crash so my interests turned to the mechanics side of the sport. I completed a motor mechanics course at night school whilst a consultant at the University Hospital in Brussels.

I currently ride a Honda 1100 Blackbird and a VRSC Night Rod Harley Davidson, having given up on driving cars altogether.

I am particularly interested in health and fitness. I am trained in Kung Fu and now exercise daily combining a free weights programme with 6 km runs.

I am interested in languages. My native language is Flemish and I am fluent in English, French and German. I also have a working knowledge of Spanish and am learning basic Russian and Japanese.

I enjoy experiencing new cultures, particularly their food and drink, and am a great fan of cinema and reading.