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CURRICULUM VITAE PERSONAL DATA Name: Scott J. Hollister EDUCATION 1976-1980 Lakeview High School, Battle Creek, Michigan 1980-1984 University of Michigan, Ann Arbor, MI; B.S.E. (Aerospace Engineering) 1984-1986 University of Michigan, Ann Arbor, MI: M.S.E. (Applied Mechanics) 1984-1986 University of Michigan, Ann Arbor, MI; M.S. (Bioengineering) 1986-1991 University of Michigan, Ann Arbor, MI; Ph.D. (Bioengineering) ACADEMIC APPOINTMENTS

2001- Associate Professor of Biomedical Engineering with tenure, University of Michigan

1998- Associate Professor of Surgery with tenure, University of

Michigan Medical School

1998- Associate Professor of Biomedical Engineering, University of Michigan

1998- Associate Professor of Mechanical Engineering, University of Michigan

1991-1998 Assistant Professor of Surgery, University of Michigan

1993-1998 Assistant Professor of Mechanical Engineering and Applied Mechanics, University of Michigan 1996-1998 Assistant Professor of Biomedical Engineering, University of Michigan

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GRANT SUPPORT Current

R01 13608 National Institutes of Health (Bioengineering Partnership Grant) Hollister (PI) "Engineering Joint Scaffolds for Concurrent Function and Regeneration,” 25% effort, $2,805,161, TDC, 9/15/01-9/14/06 R01 016129 National Institutes of Health, Hollister (PI) “Optimizing Mandibular Scaffold Modulus/Porosity Balance”, 15% effort, $1,825,604 TDC, 9/1/05-8/31/10

R01 DE 016530 Krebsbach (PI), Hollister Co-I, 10% effort, 4/1/2005-3/31/2010

$250,000 direct cost for first year Osteoblast lineage progression from human embryonic stem cells AO Foundation Krebsbach (PI), Hollister Co-I 10% effort,

1/24/2005-1/23/2008 $157,000 direct cost for first year Combinatorial therapy Alion Science and Technology, Department of the Army, Mazumder (PI), Hollister (Co-I, 10% effort) 9/1/2005 – 8/31/2006 Designed Titanium Scaffolds Made by Free-Form Fabrication for Gene/Cell Delivery for Patient-Specific Tissue Engineering

Pending National Institutes of Health, “Determining Optimal Bone Scaffold Design Parameters”, Principal Investigator, 15% effort, $1,372,911 TDC. Coulter Grant Proposal, “A Topology Designed Degradable Scaffold for Intervertebral Disc Regeneration”, Principal Investigator, $100,000 TDC.

Recent

National Institutes of Health (National Institute for Dental and Craniofacial Research) (R01 DE13416) “Designed Scaffold Architecture Influences Bone Regeneration,” Principal Investigator, 20%, $1,149,513 TDC, 9/1/00-6/30/04

National Institutes of Health (NIAMS R01 AR48414) “Material/Biologic Constructs for Skeletal Regeneration”, Co-I, 10%, $100,000, TDC, 10/1/01-9/30/03

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National Institutes of Health (R01-AR42847) "Effects of Tissue Strain Magnitude on Bone Ingrowth", Principal Investigator, 35%, $358,861 TDC, 9/30/95-8/31/98. Whitaker Foundation "Relationship of Bone Ingrowth and Adaptation to Tissue Level Strains under Controlled Implant Loads", Principal Investigator, 30%, $150,000,TDC5/1/92-5/1/95. National Institutes of Health (R55-AR42847) "Effects of Tissue Strain Magnitude on Bone Ingrowth" , Principal Investigator, 35%, $80,000 TDC, 9/15/94-9/31/96.

National Institutes of Health (National Library of Medicine) “Next Generation Internet (NGI) Implementation to serve Visible Human Datasets: Phase 2 Development of Testbeds”, Co-Investigator 20%, $6,800,000., 9/1/99-5/1/01

National Institutes of Health (R01-AR41349) "Tissue Morphology and Architecture Effects on Bone, Co-Principal Investigator, 20%, $491,480 TDC, 10/1/91-9/30/95.

Department of Surgery, The University of Michigan, Principal Investigator, $23,000 TDC, 6/1/96-5/30/97 SCIENTIFIC ACTIVITIES Study Sections NIH NIAMS, Special Study Section Member, December 17, 1997. Review of Program Project Grant on “Mechanotransduction in Bone” NIH NIAMS, Special Study Section Member, July, 1998. Special Review for RFA on “Mechanical Signaling Mechanisms in Cartilage”

NIH NIAMS, Special Study Section Member, July, 1999, Review of Program Project on “Mechanotransduction in Bone” NIH NIAMS, Special Study Section Member, April, 2001 Review of Program Project on “Mechanotransduction in Bone” NIH NIAMS, Special Study Section Member, September, 2001, Review of Program Project on “Mechanotransduction in Bone” NIH NIAMS, Special Emphasis ZAR1 TAS-B, Study Section Member, September, 2002. NIH NIBIB, Bioengineering Study Section ZRG1 SSS-M, Ad-Hoc Member, November, 2002.

Editorial Boards

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1996- Computer Methods in Biomechanics and Biomedical Engineering Reviewer 1992- Journal of Biomechanics 1993- Journal of Biomechanical Engineering 1995- Bone 1998- Journal of Bone and Joint Surgery 2003- Biomaterials 2003- Tissue Engineering 2004- International Journal of Oral and Maxillofacial Surgery 2005- Acta Biomaterialia HONORS AND AWARDS New Investigator Recognition Award, Orthopaedic Research Society, 1992 Winner of the First George W. Thorn Award for Outstanding Research, Whitaker Foundation, 1994 Whitaker Biomedical Research Conference NIH Shannon Award, 1994 The University of Michigan Henry Russell Award for Outstanding Research and Teaching, 2003 BIBLIOGRAPHY Completed Publications in Scientific Journals Peer-Reviewed Publications 1. Hollister, S.J., Fyhrie, D.P., Jepsen, K.J., Goldstein, S.A.: Application of Homogenization Theory to the Study of Trabecular Bone Mechanics, J. of Biomechanics, 24:825-839, 1991. 2. Goldstein, S.A., Matthews, L.S., Kuhn, J.L., Hollister, S.J.: Trabecular Bone Remodeling: An Experimental Model, J. of Biomechanics, 24 Supplement 1:135-152, 1991. 3. Hollister, S.J., Kikuchi, N.: A Comparison of Homogenization and Standard Mechanics Analyses for Periodic Porous Composites, Computational Mechanics, 10:73-95, 1992. 4. Hollister, S.J., Kikuchi, N., Goldstein, S.A.: Do Bone Ingrowth Processes Produce a Globally Optimized Structure?, J. Biomechanics, 26:391-407, 1993. 5. Ko, C.C., Kohn, D.H., Hollister, S.J.: Micromechanics of Implant/Tissue Interfaces, J. Oral Implantology, 18:220-230, 1992.

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6. Hollister, S.J., Brennan, J.M., Kikuchi, N.: A Homogenization Sampling Procedure for Calculating Trabecular Bone Effective Stiffness and Tissue Level Stress, J. of Biomechanics, 27:433-444, 1994. 7. Huiskes, R. and Hollister, S.J.: From Structure to Process, From Organ to Cell: Ten Year Development of FE-Analysis in Orthopaedic Biomechanics, J. Biomechanical Engineering, Trans ASME, 115:520-527, 1993 8. Hollister, S.J. and Kikuchi, N.: Homogenization Theory and Digital Imaging: A Basis for Studying the Mechanics and Design Principles of Bone Tissue, Biotechnology and Bioengineering, 43:586-596, 1994. 9. Hollister, S.J.: Mechanical Factors Influencing Total Joint Outcome, Current Orthopaedics, 9:2-8, 1995. 10. Ko, C.C., Kohn, D.H., and Hollister, S.J.: Effective Anisotropic Elastic Constants of Bimaterial Interphases: Comparison between Experimental and Analytical Techniques, J. of Materials Science: Materials in Medicine., 7:109-117, 1996. 11. Hollister, S.J., Guldberg, R.E., Kuelske, C.L., Caldwell, N.J., Richards, M. and Goldstein, S.A.: Relative Effects of Wound Healing and Mechanical Stimulus on Early Bone Response to Porous-Coated Implants, J. Orthopaedic Research., 14:654-662, 1996. 12. Hollister, S.J., Taylor, J.E. and Washabaugh, P.D.: Finite Strain Elastostatics with Stiffening Materials: A Constrained Minimization Model, J. of Applied Mechanics – Trans ASME, 64:440:442, 1997. 13. Levy, R.A., Chu, T.M.G., Halloran, J.W., Feinberg, S.E., and Hollister, S.J.: Computed Tomography-Generated Porous Hydroxyapatite Orbital Floor Prosthesis as a Prototype Bioimplant, American Journal of Neuroradiology., 18:1522-1525, 1997. 14. McCreadie, B.R. and Hollister, S.J.: Analysis of Strains Within and Surrounding an Ellipsoid Model of Lacunae and Osteocytes, Computer Methods in Biomechanics and Biomedical Engineering, 1:61-68, 1997 15. Guldberg, R.E., Caldwell, N.J., Guo, X.E., Schaffler, M., Hollister, S.J., and Goldstein, S.A.: Effects of In Vivo Mechanical Simulation on Trabecular Bone Repair, Journal of Bone and Mineral Research., 12:1295-1302, 1997. 16. Bobak, V., Christiansen, R.L., Hollister, S.J., and Kohn, D.H.: Stress-related molar responses to the Transpalatal Arch: A Finite Element Analysis, American Journal of Orthodontics and Dentofacial Orthopaedics, 112: 512-518, 1997. 17. Kikuchi, N., Hollister, S.J., and Guldberg, R.E.: An Automated Image Based Fixed Grid Analysis Model Development - From MCAE to MDA, JSAE, 963:121-124 (in Japanese), 1997.

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18. Guldberg, R.E., Hollister, S.J., Charras G.: The Accuracy of Digital Image-Based Finite Element Models, J. of Biomechanical Engineering – Trans ASME, 120:289-295, 1998. 19. Zysset P.K., Goulet R.W. and Hollister S.J.: A Global Relationship between Trabecular Morphology and Homogenized Elastic Properties, J. Biomechanical Engineering – Trans ASME., 120:640-646, 1998. 20. Lerner, A.L., Kuhn, J.L., and Hollister, S.J.: Comparison of Bone Growth Rates to Mechanical Stress and Strain Parameters, J. Biomechanics., 31:327-335, 1998.. 21. Hollister, S.J., Levy, R.A., Chu, T.M.G., Halloran, J.W., and Feinberg, S.E.: An Image Based Approach to Design and Manufacture Craniofacial Scaffolds, Int J of Oral/Maxillofacial Surgery, 29:67-71, 2000. 22. Feinberg, SE, Hollister, SJ, Halloran, JW, Chu, TM, Krebsbach, PH: A Tissue Engineering Approach to Site-Specific Reconstruction of Skeletal Structures of the Maxillofacial Region: Part 1”, Shanghai Journal of Stromatology, 9:34-38, 2000. 23. Feinberg, SE, Hollister, SJ, Halloran, JW, Chu, TM, Krebsbach, PH: A Tissue Engineering Approach to Site-Specific Reconstruction of Skeletal Structures of the Maxillofacial Region: Part 2”, Shanghai Journal of Stromatology, 9:88-93, 2000. 24. Chu, T-M. G., Halloran, J.W., Hollister, S.J., and Feinberg, S.W.: Hydroxyapatite implants with controlled internal architecture, J. of Materials Science: Materials in Medicine, 12:471-478, 2001. 25. Adachi, T., Tsubota, K., Tomita, Y. and Hollister, S.J.: Trabecular surface remodeling simulation for cancellous bone using microstructural voxel finite element methods, J. Biomechanical Engineering – Trans ASME, 123:403-409, 2001. 26. Feinberg, S.E, Hollister, S.J., Halloran, J.W., Chu, T.M., and Krebsbach, P.H.: Image-based biomimetic approach to reconstruction of the temporomandibular joint, Cells,Tissues, Organs, 169:309-321, 2001. 27. Hollister, S. J., and S. E. Feinberg. Normal and reconstructed mandibular condyle mechanics. KSME Int. J. 15: 974-981, 2001. 28. Chu, T.-M. G., Orton, D.G., Hollister, S.J., Feinberg, S.E., and Halloran, J.W.: Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures”, Biomaterials, 23:1283-1293, 2002. 29. Brock, K.K., Hollister, S.J., Dawson, L.A., and Balter, J.M., Creating a 4-Dimensional model of the liver using finite element analysis, Medical Physics, 29:1403-1405, 2002.

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30. Hollister, S.J., Maddox, R.D., and Taboas, J.M., Optimal Design and Fabrication of Scaffolds to Mimic Tissue Properties and Satisfy Biological Constraints, Biomaterials, 23:4095-4103, 2002. 31. Taboas, J.M., Maddox, R.D., Krebsbach, P.H. and Hollister, S.J., Indirect Solid Free Form Fabrication of Local and Global Porous, Biomimetic and Composite 3D Polymer-Ceramic Scaffolds, Biomaterials , 24:181-194, 2003 32. Das, S., Hollister, S.J., Flanagan, C., Adewunmi, A., Bark, K., Chen, C., Ramaswamy, K., Rose, D. and Widjaja, E., Freeform Fabrication and Testing of Nylon-6 Tissue Engineering Scaffolds, Rapid Prototyping Journal, 9:43-49, 2003. 33. Brock, KK, McShan, DL, Ten Haken, RK, Hollister, SJ, Dawson, LA, and Balter, JM, Inclusion of organ deformation in dose calculations, Medical Physics, 30:290-295, 2003. 34. McCreadie, B.R., Hollister, S.J., Schaffler, M.B., and Goldstein, S.A., Osteocyte lacuna size and shape in women with and without osteoporotic fracture, J. Biomechanics. 37:563-572, 2004.

35. Lin, CY, Kikuchi, N, and Hollister, SJ, “A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity”, J. Biomechanics, 37:623-636, 2004.

36. Lin, CY, Hsiao, CC, Chen, PQ and Hollister, SJ, “A new spinal cage design using integrated global and local topology optimization”, Spine, 15:1747-1754, 2004.

37. Schek, RD, Hollister, SJ, and Krebsbach, PH, “Delivery and protection of adenoviruses using biocompatible hydrogels for localized gene therapy”, Molecular Therapy, 9:130-138, 2004.

38. Hollister, S. J.; Lin, C. Y.; Lin, C. Y.; Schek, R. D.; Taboas, J. M.; Flanagan, C. L.; Saito, E.; Williams, J. M.; Das, S.; Wirtz, T., and Krebsbach, P. H. “Design and fabrication of scaffolds for anatomic bone reconstruction.” Med J Malaysia. May; 59 Suppl B:131-2, 2004.

39. Schek, RD, Taboas, JM, Segvich, SJ, Hollister, SJ, and Krebsbach, PH, (2004) “Engineered Osteochondral Grafts using Biphasic Composite Solid Free Form Fabricated Scaffolds”, Tissue Engineering, 10:1376-1385.

40. Diggs, AB, Halloran, JW, Hollister, SJ (2005) “Cathodoluminescence as a method of microstructure characterization of biphasic ceramics composed of hydroxyapatite and β-tricalcium phosphate”, Key Engineering Materials, 284-286:333-336.

41. Williams, J.M., Adewunmi, A., Schek, R.M., Flanagan, C.L., Krebsbach, P.H., Feinberg, S.E., Hollister, S.J., and Das, S., (2005) “Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering”, Biomaterials, 26:4817-4827.

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42. Hollister, S.J., Lin, C.Y., Saito, E., Lin, C.Y., Schek, R.M., Taboas, J.M., Williams, J.M., Partee, B., Flanagan, C.L., Diggs, A., Wilke, E.N., Van Lenthe G.H., Muller, R., Wirtz, T., Das, S., Feinberg, S.E., and Krebsbach, P.H., (2005) “Engineering craniofacial scaffolds”, Orthodontics and Craniofacial Research, 8:162-173

43. Schek, R.M., Taboas, J.M., Hollister, S.J., and Krebsbach, P.H., (2005) “Tissue engineering osteochondral implants for Temporomandibular joint repair”, Orthodontics and Craniofacial Research. 8:313-319.

44. Lin, C.Y., Schek, R.M., Mistry, A.S., Shi, X., Mikos, A.G., Krebsbach, P.H., and Hollister, S.J., (2005) “Functional bone engineering using ex vivo gene therapy and topology optimized, biodegradable polymer composite scaffolds”, Tissue Eng 11:1589-1598.

45. Hollister, S.J. (2005) “Porous scaffold design for tissue engineering”, Nature Materials, 4:518-524.

46. Schek, R.M., Wilke, E.N., Hollister, S.J. and Krebsbach, P.H., (2006) “Combined use of designed solid scaffolds and adenoviral gene therapy for skeletal tissue engineering”, Biomaterials, 27:1160-1166.

47. Mao, J.J., Giannobile, W.V., Helms, J.A., Hollister, S.J., Krebsbach, P.H., Longaker, M.T., and Shi, S., “Craniofacial tissue engineering”, J. Dental Research, (in press).

48. Partee, B., Hollister, S.J., and Das, S., “Selective laser sintering process optimization for layered manufacturing of CAPA 6501 Polycaprolactone Bone Tissue Enginering Scaffolds”, ASME J. of Manufacturing Science Eng. (in press)

Submitted Publications 1. Adachi, T., Osako, Y., Tanaka M., Hojo, M. and Hollister, SJ “A framework for optimal design of porous scaffold microstructure using computational simulation of bone regeneration”, Biomaterials. 2. Lin, C.Y., Nicholson, R., Brahma, B., Hollister, S.J. and LaMarca, F. “Image-based Finite-Element Analysis of L5-S1 Charite Artificial Disc Replacement”, J. Neurosurgery – Spine. 3. Hollister, SJ and Lin, CY. “Computational Design of Tissue Engineering Scaffolds”, Computer Methods in App. Mech. and Eng. Chapters in Books 1. Goldstein, S.A, Hollister, S.J., Kuhn, J.L., Kikuchi, N.: The Mechanical and Remodeling Characteristics of Trabecular Bone, in Mow, V. ed, Biomechanics of Diarthrodial Joints, pp. 61-81, 1990.

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2. Hollister, S.J., Brennan, J.M., and Kikuchi, N.: Homogenization Sampling Analysis of Trabecular Bone Microstructural Mechanics, in Middleton, J. ed, Recent advances in computer methods in biomechanics and biomedical engineering, Books & Journals Int. LTD, Swansea, UK., pp. 308-317, 1992. 3. Hollister, S.J. and Riemer, B.A.: Digital Image based Finite Element Analysis for Bone Microstructure using Conjugate Gradient and Gaussian Filter Techniques, Proceedings Mathematical Methods in Imaging II, SPIE 1993, pp. 95-106. 4. Hollister, S.J.: The Ability of Representative Volume Element (RVE) Methods to Bound Trabecular Tissue Strains: Dependence on Assumed Boundary Conditions, World Congress of Biomechanics Symposium on Trabecular Bone, World Scientific Publications, 1995, p. 147-156. 5. Hollister, S.J. and Goldstein, S.A.: Relationships Between Trabecular Tissue Strains and Bone Adaptation under Controlled Implant Loads, World Congress of Biomechanics Symposium on Trabecular Bone, World Scientific Publications, 1995, p. 51-64. 6. Borodkin, J.L. and Hollister, S.J.: A New Method for Correcting Boundary Condition Errors on Microstructural FEA Models of Trabecular Bone and Implant Interfaces, Computer Methods in Biomechanics and Biomedical Engineering, 1996, p. 105-114. 7. Kohn, D.H., Ko, C.C., Hollister, S.J., Snoeyink, Dl, Awerbuch, J., and Ducheyne, P.: Methods of Detecting and Predicting Microfracture in Titanium", Medical Applications of Titanium and Its Alloys: The Material and Biological Issues, ASTM STP 1272, S.A. Brown and J.E. Lemons, Eds., American Society for Testing and Materials, Philadelphia, PA., 117-135, 1996. 8. Hollister, S.J., Chu, T.M., Guldberg, R.E., Zysset, P.K., Levy, R.A., Halloran, J.W., Feinberg, S.E.: Image based design and manufacture of scaffolds for bone reconstruction, in Pedersen, P. and Bendsoe, M. Eds., IUTAM Synthesis in Biosolid Mechanics, Kluwer Press 9. Feinberg, S.E. Hollister, S.J., Chu, T.M., Halloran, J.W., and Krebsbach, P.H. Biomimetic reconstruction of the Temporomandibular Joint, Oral and Maxillofacial Clinics of North America, Vol 12:149-160, 2000. 10. Hollister, SJ, Chu, TM, Halloran, JW, Feinberg, SE “Design and Manufacture of Bone Replacement Scaffolds, SC Cowin, Ed., Bone Mechanics Handbook, CRC Press, pp. 36:1-14, 2001. 11. Hollister, SJ, Zysset, PK, Guldberg, RE, Chu, TM, and Halloran, JW, “Engineering Microstructures to Evaluate and Replace Trabecular Bone,” in Noninvasive Assessment of Trabecular Bone Architecture and Competence of Bone, Majumdar, S. and Bay, B., eds., “Advances in Experimental Medicine and Biology, 496:199-211. Kluwer Academic / Plenum Publishers, New York.

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12. T.M. Chu, G.A. Brady, W. Miao, J.W. Halloran, S.J. Hollister, D. Brei, 1999, “Ceramic SFF by direct and indirect stereolithography” in Materials Research Society Symposium Proceedings Vol. 542 Solid Freeform and Additive Fabrication. Materials Research Society, Pittsburgh, PA. pp. 119-123 13. Suman Das and Scott Hollister, Tissue Engineering Scaffolds, Encyclopedia of Materials-Science and Technology, K.H.J. Buschow, R.W. Cahn, M.C. Flemings, B. Ilschner, E.J. Kramer and S. Mahajan (Eds.), Elsevier, 2002. 14. Scott J. Hollister, Juan M. Taboas, Rachel D. Schek, Cheng-Yu Lin, and Tien-Min Chu, “Design and Fabrication of Bone Tissue Engineering Scaffolds”, (2004) in Bone Tissue Engineering, ed. by J. Hollinger, CRC Press, p. 167-192. 15. Lin, CY, Hollister, SJ, Krebsbach, PH, and LaMarca, F, “New Adjunct in Spine Interbody Fusion: Designed Bioasbsorbable Cage with Cell-Based Gene Therapy”, (in press) in Innovations in Spinal Reconstruction: Clinical Examples of Basic Science, Biomechanics, and Engineering, Lewandrowski, K., Park, P, McLain RF, Kalfas, IH, Yaszemski, MJ and Trantolo, DJ, ed. INVITED PRESENTATIONS 1. Invited Panelist, Implant Interface Workshop, Combined Meeting of the Orthopaedic Research Societies of USA, Japan, and Canada; Banff, Canada, October 21-23, 1991. 2. "Representative Volume Element Analysis of Trabecular Bone: Evaluation and Application to study Trabecular Bone Adaptation, invited lecture, Department of Mechanical Engineering, Section of Applied Mechanics, Stanford University, October, 1993. 3. "Orthopaedic Biomechanics", invited lectures, Michigan Orthopaedic Society, Mackinac Island, Michigan, May, 1994 4. "Mechanics of Bone, Implants, and Bone-Implant Composites", invited lecture, Department of Orthopaedics, Orthopadische Abteilung de Rehabilitationskrankenhauses, Ulm, Germany, July, 1994 5. "Effects of Tissue Strain Magnitude on Bone Adaptation", invited lecture, Department of Orthopaedic Surgery, University of Missouri, Kansas City, December, 1995 6. "Mechanical Influences on Bone Adaptation: Studies from Wolff to the Present", invited lecture, Department of Mechanical Engineering, Instituto Superior Technico, Lisbon, Portugal, July, 1995.

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7. "Computational Methods in Bioengineering", invited lecture, Quint Corporation, Tokyo, Japan, May, 1996. 8. "Image Based CAE Methods", invited lecture, Toyota Central Research Laboratories, Nagoya, Japan, May, 1996. 9. "Bridging the Gap between Animal Models and Cell Cultures: The Use of Computational Modeling for Hypothesis Testing", Gordon Research Conference on Bioengineering and Orthopaedics, August 1, 1996, Invited Lecture 10. "Relating Bone Adaptation to Tissue Level Strains: A Hierarchical Approach to Quantifying Wolff's Law, Invited Lecture, Korean Institute of Science and Technology, Biomedical Engineering Division, September 13, 1996, Seoul, South Korea. 11. "A Hierarchical Approach to Studying Bone Mechanics and Adaptation", Invited Lecture, Tulane University, December 12, 1996, New Orleans, Louisiana 12. "Quantifying Bone Mechanics and Adaptation using Homogenization Theory and Digital Imaging", Invited presentation, Workshop on Comparing Structural Optimization and Tissue Adaptation Models, Courant Institute, New York University, January, 1997, New York. 13. "Image Based Analysis and Manufacture of Bone Microstructure", Invited Speaker, Korean Society of Mechanical Engineers Annual Meeting, April 25, 1997, South Korea 14. "Analysis, Design, and Manufacture of Bone Microstructure", Invited Keynote Speaker, Third International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, May 7-10, 1997, Barcelona, Spain. 15. “Image Based Design and Manufacture of Scaffolds for Bone Reconstruction”, Invited Speaker, International Union of Theoretical and Applied Mechanics, May 24-27, 1998, Lyngby, Denmark. 16. Invited Keynote Speaker, 4th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Oct. 13-16, 1999, Lisbon, Portugal 17. Invited Speaker, American Association of Dental Research, Symposium on Biomimetic Design of Dental Materials, Apr. 1-4, 2000, Washington, D.C. 18. Invited Speaker, University of Minnesota Dental School, Dean’s Seminar Series, March 30, 2001. 19. Invited Keynote Speaker, 5th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Oct. 31- Nov. 4, 2001, Rome, Italy. 20. Invited Speaker, Worcester Polytechnic Institute, Biomedical Engineering Seminar, February, 2002.

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21. Invited Speaker, University of Wisconsin, Biomedical Engineering Seminar, May, 2002. 22. Invited Speaker, 15th International Bone Densitometry Workshop, “Bone Tissue Engineering: the Role of Non-Invasive Assessment”, July, 21-26, 2002. Monterey, Ca. 23. Invited Course/Speaker, Industrial Materials Institute, National Research Council of Canada, Montreal, Canada, March 5, 2003. “Skeletal Tissue Engineering”. 24. Invited Speaker, Bioengineering Seminar, Mayo Clinic, Rochester, Minnesota, “Bone/Joint Scaffolds: Design, Fabrication and Testing”, July 24, 2003. 25. Invited Keynote Speaker, Computational Bioengineering Symposium, 7th US National Congress on Computational Mechanics, July 27-31, 2003, Albuquerque, New Mexico. 26. Invited Speaker, Kyungbuk National University Medical School, “Bone/Joint Scaffolds: Design, Fabrication and Testing”, September 7, 2003, Daegu, Korea. 27. Invited Speaker, Korean Institute of Science and Technology, “Bone/Joint Scaffolds: Design, Fabrication and Testing”, September 7, 2003, Seoul, Korea. 28. Invited Speaker, Kobe University, “Bone/Joint Scaffolds: Design, Fabrication and Testing”, September 9, 2003, Kobe, Japan. 29. Invited Keynote Speaker, International Conference on Advanced Technology in Experimental Mechanics, Nagoya, Japan, September 10-12, 2003. 30. Invited Keynote Speaker, 7th World Biomaterials Conference, May 17-21, 2004, Sydney, Australia 31. Invited Keynote Speaker, International Conference on Biomaterials and Tissue Engineering, May 24-26, 2004, Kuala Lumpur, Malaysia. 32. Invited Speaker, Regenerate 2004: Tissue Engineering the Human Body, “Design, Fabrication and Testing of Skeletal Engineering Scaffolds”, Seattle, June 7-9, 2004. 33. Invited Speaker, International Union of Theoretical and Applied Mechanics Symposium on the Mechanics of Biological Tissues, Graz, Austria, June 27-July 2, 2004. 34. Invited Speaker, (presentations are only by invitation), 2004 Gordon Research Conference on Musculoskeletal Biology and Bioengineering, Orthopaedic Tissue Engineering from Basic Science to Clinical Application, Andover, New Hampshire, July 25-29, 2004. 35. Invited Speaker, COAST Symposium on Craniofacial Skeletal Bioengineering, “Optimal Design and Fabrication of Scaffolds to Mimic Tissue Properties and Satisfy Biological Contraints”, Asilomar, California, August 27-30, 2004.

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36. Invited Speaker, COAST Symposium on Craniofacial Skeletal Bioengineering, “Engineering Scaffolds for Craniofacial and Temporomandibular Joint Reconstruction”, Asilomar, California, August 27-30, 2004. 37. Invited Speaker, Kyoto University Medical School, “Designed/Fabricated Scaffolds for Spine Fusion Delivery Osteogenic Factors, Kyoto, Japan, Sept. 16, 2004. 38. Invited Speaker, Kyoto University College of Engineering Special Center of Excellence Symposium, ‘Engineering Skeletal Reconstruction”, Kyoto, Japan, Sept. 17, 2004. 39. Invited Speaker, Research Conference Swine in Biomedical Engineering, “Pigs as a Model for Musculoskeletal Reconstruction”, Jan. 29, 2005. 40. Invited Speaker, Biomedical Engineering Seminar, “Engineering Scaffolds for Tissue Reconstruction”, Rensselaer Polytechnic Institute, Troy, New York, March 9, 2005. 41. Invited Speaker, American Academy of Oral and Maxillofacial Surgerons (AAOMS), “Scaffolds for Hard Tissue Applications”, Rosemont, Illinois, May 5, 2005. 42. Invited Speaker, Regenerative Medicine Showcase, “Scaffold Development for Tissue Engineering”, The University of Michigan, Ann Arbor, MI, May 11, 2005. 43. Invited Speaker, Spine Conference, “Invertebral Disk: Normal, Degenerated and Re-engineered Structure-Function”, Department of Neurosurgery, The University of Michigan, Ann Arbor, MI May 18, 2005. 44. Invited Speaker, Symposium for the Inauguration of the National Research Center of Canada Industrial Materials Institute Biomedical Materials Laboratory, “Scaffold Design for Tissue Engineering”, Industrial Materials Institute, Montreal, Canada June 7, 2005. 45. Invited Speaker, International Workshop on Biomanufacturing, Beijing, China, June 29-July 1, 2005. 46. Invited Speaker, Biosurf VI – Tissue/material interaction, Lausanne, Switzerland, Sept. 21-23, 2005. 47. Invited Speaker, Biomedical Engineering Society Meeting, Orthopaedic Tissue Engineering Session, Baltimore, MD, October 1, 2005. 48. Invited Speaker, :”The Dr. Bernard and Rhoda Sarnat Lectureship in bone biology”, Tel Aviv University, Tel Aviv, Israel, November 4, 2005. 49. Invited Speaker, Japanese Society of Mechanical Engineering Conference, Niigata, Japan, Jan. 13-14, 2006.

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50. Invited Speaker, 7th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Cote d’ Azur, France, March 22-25, 2006. 51. Invited Speaker, World Congress on Tissue Engineering and Regenerative Medicine, April 24-27, 2006. Abstracts and Preliminary Communications 1. Hollister, S.J., Guldberg, R.E., Kuelske, C.L., Caldwell, N.J., Richards, M. and Goldstein, S.A.: Effects of Healing and Mechanical Stimulus on Bone Adaptation to Porous Coated Implants at Five Weeks, Trans. 41st Meeting Orthopaedic Research Society, p. 556, 1995. 2. Guldberg, R.E., Goldstein, S.A., Caldwell, N.J., Kuelske, C.L., Guo, X.E., Moalli, M., Hollister, S.J.: Mechanical Influences on Trabecular Bone Repair, Trans. 41st Meeting Orthopaedic Research Society, p. 175., 1995. 3. Guo, X.E., Weissman, D.E., Goulet, R.W., Hollister, S.J., Derwin, K.A., Goldstein, S.A.: Characterization of Local Failure in Vertebral Trabecular Bone, Trans. 41st Meeting Orthopaedic Research Society, p. 532, 1995. 4. Wenzel, T.E., Fyhrie, D.P., Hollister, S.J.: A Simple Mathematical Model for Strain Distributions in Cancellous Bone, Trans. 41st Meeting Orthopaedic Research Society, p. 537, 1995. 5. Riemer, B.A. and Hollister, S.J.: Analysis of Osteocyte and Lacunar Strains Using an Idealized Finite Element Model, Trans. 41st Meeting Orthopaedic Research Society, p. 540, 1995. 6. Rouleau, J.P., Palmer, M.L., Hollister, S.J., Moore, D.C. and Huiskes, R.: Development of a Local Homogenization Model of the Trabecular Bone-Cement Interface, Trans. 41st Meeting Orthopaedic Research Society, p. 752, 1995. 7. Kohn, D.H., Ko, C.C. and Hollister, S.J.: Experimental Validation of Interfacial Elastic Constants Predicted by Homogenization Theory, Trans. 41st Meeting Orthopaedic Research Society, p. 753, 1995. 8. Guldberg, R.E. and Hollister, S.J.: Finite Element Solution Errors Associated with Digital Image-Based Mesh Generation, Advances in Bioengineering, ASME BED Vol. 24, 1994. 9. Ko, C.C., Kohn, D.H., and Hollister, S.J.: Characterizing Elastic Properties of Bimaterial Interphase Composites: Comparison of Experimental and Analytical Results, Advances in Bioengineering, ASME BED Vol. 24, 1994.

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10. Kohn, D.H., Ko, C.C., and Hollister, S.J.: Microstructural Modeling of Dental Implant/Tissue Interfaces: Global and Local Stresses, Advances in Bioengineering, ASME BED Vol. 24, 1994. 11. Hollister, S.J. and Kikuchi, N.: Implant Design Synthesis using Topology Optimization and Digital Imaging, Advances in Bioengineering, ASME BED Vol. 24, 1994. 12. Hollister, S.J. and Chouinard, B.R.: Prediction of Bone Adaptation Around an Optimized Tibial Component Design, Advances in Bioengineering, ASME BED Vol. 24, 1994. 13. Hollister, S.J. and Goldstein, S.A.: Relationship of Bone Ingrowth and Adaptation to Tissue Level Strains under Controlled Implant Loads, Whitaker Foundation Biomedical Engineering Research Meeting, Snowbird, Utah, 1994. 14. Hollister, S.J., Borodkin, J.L., and Guldberg, R.E.: Large Scale Analysis of Bone Micromechanics using Digital Image-Based Finite Element Methods, Application of High Performance Computing in Engineering, Pittsburgh Supercomputer Center, p. 29-31, 1994. 15. Hollister, S.J. and Goldstein, S.A.: Trabecular Tissue Strains Before and After Bone Adaptation to Controlled Implant Loads, 2nd World Congress of Biomechanics Proceedings, Vol. 2, p. 234a, 1994. 16. Goldstein, S.A., Hollister, S.J., Guldberg, R.E., Germiller, J., Richards, M., and Bonadio, J.: Mechanical Influences on Bone Adaptation, 2nd World Congress of Biomechanics Proceedings, Vol. 1, p. 45b, 1994. 17. Hollister, S.J. and Kikuchi, N.: The Ability of Representative Volume Element (RVE) Methods to Bound Trabecular Tissue Strains: Dependence on Assumed RVE Boundary Conditions, 2nd World Congress of Biomechanics Proceedings, Vol. 1, p. 52a, 1994. 18. Hollister, S.J., Guldberg, R.E., Kuelske, C.L., Mosier, S.M., Yadmark, C., Richards, M., Albright, J.C., and Goldstein, S.A.: Relative Effects of Wound Healing and Mechanical Stimulus on Early Bone Adaptation to Porous Coated Implants, 2nd World Congress of Biomechanics Proceedings, Vol. 1, p. 242a, 1994. 19. Ko, C.C., Kohn, D.H., Hollister, S.J. and Goldstein, S.A.: Comparison between Predicted Tissue Level Strains and Measured Ingrowth in Porous Coated Implants, Proc. 21st Society for Biomaterials Meeting, 1995. 20. Kohn, D.H., Ko, C.C., and Hollister, S.J.: Comparison of Composite Theories for Predicting Effective Elastic Constants with Experimental Data, Proc. 21st Society for Biomaterials Meeting, 1995.

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21. Kohn, D.H., Ko, C.C., and Hollister, S.J.: Predicted Differences in Ingrowth and Damage Between Fully and Partially Porous Coated Total Hip Replacements, Proc. 21st Society for Biomaterials Meeting, 1995. 22. Kohn, D.H., Ko, C.C. and Hollister, S.J.: Experimental Validation of Analytically Determined Interfacial Material, Journal of Dental Research Abstracts of the 24th Annual Meeting of the American Association for Dental Research 74: 92 1995. 23. Palmer, M.L., Hollister, S.J., and Kikuchi, N.: On the Optimality of Bone Structure in the Proximal Femur, Trans. 40th Meeting Orthopaedic Research Society, p. 59, 1994. 24. Riemer, B.A., Eadie, J.S., Weissman, D.E., Haut, K.M., Hollister, S.J. and Goldstein, S.A.: Characterization of the Architecture, Tissue Properties, and Continuum Behavior of Aging Trabecular Bone, 40th Meeting Orthopaedic Research Society, p. 59, 1994. 25. Borodkin, J.L., Eadie, J.S., Choi, K., Hollister, S.J., Goldstein, S.A.: The Effect of Mechanical Stimuli on Bone Ingrowth into Porous Coated Implants, 40th Meeting Orthopaedic Research Society, p. 582, 1994. 26. Kohn, D.H., Ko, C.C., and Hollister, S.J.: Global/Local Finite Element Analysis of Porous Coated Total Hip Replacements, Advances in Bioengineering, ASME BED Vol. 26, p. 231, 1993. 27. Hollister, S.J. and Goldstein, S.A.: Relationship of Trabecular Tissue Strain Alterations to Bone Adaptation under Controlled Implant Loads, Advances in Bioengineering, ASME BED Vol. 26, p. 145, 1993. 28. Huiskes, R. and Hollister, S.J.: From Structure to Process, From Organ to Cell: Ten Year Development of FE-Analysis in Orthopaedic Biomechanics, ASME BED Vol. 24, 1993 Bioengineering Conference, p. 1, 1993. 29. Hollister, S.J. and Goldstein, S.A.: Trabecular Tissue Strain Estimates for Bone Adapted to Controlled Implant Loads, ASME BED Vol. 24, 1993 Bioengineering Conference, p. 254-257, 1993. 30. Hollister, S.J. and Kikuchi, N.: Comparison of Trabecular Tissue Strains Computed by Homogenization Theory to Direct Finite Element Calculations, ASME BED Vol. 24, 1993 Bioengineering Conference, p. 258-261, 1993. 31. Kohn, D.H., Ko, C.C. and Hollister, S.J.: Localized Mechanics of Dental Implants, ASME BED Vol. 24, 1993 Bioengineering Conference, p. 331-334, 1993. 32. Kohn, D.H., Ko, C.C. and Hollister, S.J.: Local Properties of Porous Coating/Tissue Interfacial Zone Based on Homogenization Theory, ASME BED Vol. 24, 1993 Bioengineering Conference, p. 335-338, 1993.

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33. Hollister, S.J., Ko, C.C. and Kohn, D.H.: Bone Density around Screw Thread Dental Implants Predicted using Topology Optimization, ASME BED Vol. 24, 1993 Bioengineering Conference, p. 339-342, 1993. 34. Hollister, S.J., Weissman, D.E. and McCubbrey, D.A.: A Modeling Procedure to Evaluate Vertebral Body Mechanics from Trabecular Microstructural Properties, Proc. 39th Orthopaedic Research Society Meeting, p. 176, 1993. 35. Kohn, D.H., Ko, C.C. and Hollister, S.J.: Effect of Tissue Modulus, Symmetry and Fibrous Tissue on the Local Properties of a Porous Coating/Tissue Interfacial Zone, Proc. 39th Orthopaedic Research Society Meeting, p. 223, 1993. 36. Kohn, D.H., Ko, C.C. and Hollister, S.J.: Coupled Global/Local Modeling of Porous Coated Implants: Error Estimates for Different Loading Conditions, Proc. 39th Orthopaedic Research Society Meeting, p. 469, 1993. 37. Flechtenmacher, J., Borodkin, J.L., Hollister, S.J. and Dedrick, D.K.: Tibial Contact Pressure Distribution Changes in the Canine Cruciate Ligament Transection Model of Osteoarthrosis, Proc. 39th Orthopaedic Research Society Meeting, p. 721, 1993. 38. Goldstein, S.A., Ku, J.L., Hollister, S., Kayner, D.C., Matthews, L.S.: The Effects of Applied Stress on Experimentally Controlled Remodeling in Trabecular Bone. Orthopaedic Transactions, 10(2):318, 1986. 39. Hollister, S.J., Goldstein, S.A., Ku, J.L., Matthews, L.S.: An Experimental Evaluation of the Relationship Between Strain Energy Density and Trabecular Bone Remodeling. Transactions of the Orthopaedic Research Society, 11:433, 1986. 40. Goldstein, S.A., Ku, J.L., Kayner, D.C., Hollister, S., Matthews, L.S.: Trabecular Bone Remodeling. Journal of Biomechanics, 19(6):475, 1986. 41. Goldstein, S.A., Ku, J.L., Hollister, S.J., Goulet, R.W., Champlain, F.W., Matthews, L.S.:Experimentally Controlled Trabecular Bone Remodeling. Transactions of the 33rd Orthopaedic Research Society, 11:461, 1987. 42. Goldstein, S.A., Kuhn, J.L., Hollister, S.J., Goulet, R.W., Matthews, L.S. : Experimentally Induced Trabecular Bone Remodeling. Amer. Soc. Mech. Eng. Winter Meeting, December, 1987. 43. Goldstein, S.A., Kuhn, J.L., Hollister, S.J., Goulet, R.W., Loubert, P.V., Sweet, K., Matthews, L.S.: The Relationship Between Experimentally Controlled Loads and Trabecular Bone Remodeling. Transactions of the Orthopaedic Research Society, 13:102, 1988. 44. Hollister, S.J., Goldstein, S.A., Kuhn, J.L., Matthews, L.S.: Correlation of Finite Element Stress Predictions with Trabecular Bone Remodeling In Vivo: Effects of Mesh

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Refinement and Mechanical Property Assumptions. Transactions of the Orthopaedic Research Society., 13:233, 1988. 45. Hollister, S.J., Fyhrie, D.P., Jepsen, K.J., Goldstein, S.A.: A New Procedure for Calculating Apparent Bone Properties and Tissue Micro-Stresses using Homogenization Theory. Transactions of the Orthopaedic Research Society, p. 266, 1989. 46. Goldstein, S.A., Hollister, S.J., Kuhn, J.L., Goulet, R.W., Viviano, D., Loubert, P.V., Matthews, L.S.: Trabecular Bone Remodeling in Response to Controlled Implanted Mediated Load, 1989 Joint Biomechanics Symposium, 3rd Joint ASCE/ASME Mechanics Conference, p. 291. 47. Hollister, S.J., Fyhrie, D.P., Jepsen, K.J., Goldstein, S.A.: An Analysis of Trabecular Bone Micro-Mechanics using Homogenization Theory with Comparison to Experimental Results, Transactions of the International Congress of Biomechanics, 12:110, 1989. 48. Fyhrie, D.P., Jepsen, K.J., Hollister, S.J., Goldstein, S.A.: Predicting Trabecular Bone Strength and Micro-Strains using Homogenization Theory: Application to a Vertebra, Transactions of the International Congress of Biomechanics, 12:173, 1989. 49. Fyhrie, D.P., Hollister, S.J., Jepsen, K.J.: Approximating the Microstructural Prediction of Cancellous Bone Strength using the Tsai-Wu Failure Criterion, Transactions of the American Society of Biomechanics, 13:28, 1989. 50. Goldstein, S.A., Hollister, S.J., Fyhrie, D.P., Jepsen, K.J., McCubbrey, D.A., Choi, K.: Factors Affecting the Interface between Porous Ingrowth Surfaces and Trabecular Bone, Advances in Bioengineering, Winter Meeting ASME, 1989. 51. Hollister, S.J., Goldstein, S.A., Jepsen, K.J., Goulet, R.W.: Continuum and Microstructural Stress Morphology Relationships for Trabecular Bone Subject to Controlled Implant Loads, Transactions of the Orthopaedic Research Society, p. 74, 1990. 52. Fyhrie, D.P., Hollister, S.J.: A Tissue Strain Remodeling Theory for Trabecular Bone using Homogenization Theory, Transactions of the Orthopaedic Research Society, p. 76, 1990. 53. Fyhrie, D.P., Hollister, S.J.: Comparison of a Trabecular Tissue Strain Remodeling Theory to Experimental Results, Transactions of the Orthopaedic Research Society, p. 107, 1990. 54. Hollister, S.J., Goulet, R.W., Fyhrie, D.P., Goldstein, S.A.: Predicting the Dependence of Trabecular Bone Stiffness on Microstructure, The Federation of American Societies for Experimental Biology Journal, Vol. 4, 3:A822, 1990. 55. Fyhrie, D.P., Hollister, S.J.: Building Morphologically Exact Mechanical Models for Cancellous Bone, 7th European Society of Biomechanics meeting, Denmark, 1990.

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56. Hollister, S.J., Goulet, R.W., Goldstein, S.A.: Predicting Trabecular Bone Stiffness using Two Methods of Microstructural Analysis, Abstracts of the First World Congress of Biomechanics, Vol. I, p. 210. 57. Fyhrie, D. P., Hollister, S. J.: Homogenization Theory Applied to Cancellous Bone Analysis, Abstracts of the First World Congress of Biomechanics, Vol. II, p. 46. 58. Fyhrie, D. P., Hollister, S. J.: The Effect of Microstructure on the Prediction of Stress, Abstracts of the First World Congress of Biomechanics, Vol. II, p. 228. 59. Goldstein, S. A., Kuhn, J. L., Goulet, R., Choi, K., Hollister, S. J., Ciarelli, M. J., Matthews, L. S.: Properties and Remodeling of Trabecular Bone, Abstracts of the First World Congress of Biomechanics, Vol. II, p. 116. 60. Hollister, S.J., Kikuchi, N., Suzuki, K., Goldstein, S.A.: Predicting Trabecular Bone Ingrowth Patterns using a Structural Topology Optimization Scheme, Proceedings of the 14th American Society of Biomechanics meeting, p. 1990. 61. Hollister, S.J., Kikuchi, N., Borodkin, J.L., Goldstein, S.A.: A Study of Microstructural Analysis Methods: Implications for Modeling Trabecular Bone Microstructure, Advances in Bioengineering, p. 387-390., 1991. 62. Hollister, S.J., Kikuchi, N., Goldstein, S.A.: Effects of Implant Interface Design on Bone Ingrowth Predicted using Topology Optimization, Proceedings of the 37th Annual Meeting of the Orthopaedic Research Society, p. 108. 63. Fyhrie, D.P., Hollister, S.J.: A Method for Homogenization Analysis of Cancellous Bone using Standard Finite Element Programs, Proceedings of the 37th Annual Meeting of the Orthopaedic Research Society, p. 476. 64. Hollister, S.J., Kikuchi, N., and Goldstein, S.A.: Do Bone Ingrowth Processes Produce a Mechanically Optimized Structure?, Combined Meeting of the Orthopaedic Research Societies of U.S.A., Japan, and Canada, Banff, Canada, 1991. 65. Fyhrie, D.P., Hollister, S.J., Schaeffler, M.B., and Kimura, J.: Structural Transformations Indistinguishable by Point-Count Stereology, 15th Annual Meeting American Society of Biomechanics, Tempe, Arizona, October 16-18, 1991. 66. Hollister, S.J. and Kikuchi, N.: Direct Analysis of Trabecular Bone Stiffness and Tissue Level Mechanics using an Element-By-Element Homogenization Method, Proceedings 38th Annual Meeting Orthopaedic Research Society, p. 559. 67. Ko, C., Kohn, D.H., and Hollister, S.J.: Stress Analysis of the Bone/Implant Interfacial Zone accounting for Localized Architecture, Proceedings 38th Annual Meeting Orthopaedic Research Society, p. 74.

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68. Ko, C., Kohn, D.H., and Hollister, S.J.: Analysis of an Implant/Bone Interfacial Zone using Homogenization Theory, American Association for Dental Research, March 11-15, 1992, Boston, MA. 69. Ko, C., Kohn, D.H., and Hollister, S.J.: Analysis of Implant Interfaces: Error Estimate and Effect of Fibrous Tissue, American Association for Dental Research, March 11-15, 1992, Boston, MA. 70. Kohn, D.H., Ko, C.C., and Hollister S.J.: Stress Analysis of Porous Coated Total Joint Replacements: Coupled Global/Local Modeling, Advances in Bioengineering, p. 297-300, 1992. 71. Kohn, D.H., Ko, C.C., and Hollister S.J.: Localized Stress Analysis of Dental Implants using Homogenization Theory, Advances in Bioengineering, p. 607-610, 1992. 72. Lerner, A.L., Ruf, C.L., Hollister, S.J., and Kuhn, J.L.: Comparison of Bone Growth Rates to Mechanical Parameters in a Three-Dimensional Model of the Rabbit Distal Femur, Trans. 42nd Orthopaedic Research Society Meeting, Feb., 1996, p. 127. 73. Guldberg, R.E., Goldstein, S.A., Hollister, S.J., and Caldwell, N.J.: Mechanical Loading Effects on Extracellular Matrix Organization and Mineral Content during Trabecular Bone Formation, Trans. 42nd Orthopaedic Research Society Meeting, Feb., 1996, p. 130. 74. Smith, E.A., Guo, X.E., Goulet, R.W., Hollister, S.J. and Goldstein, S.A: Prediction of Local Strains in Human Vertebral Bone Specimens using CT-Based Finite Element Models, Trans. 42nd Orthopaedic Research Society Meeting, Feb., 1996, p. 604. 75. Goulet, R.W. and Hollister, S.J.: Determination of Minimum Microstructural Analysis Volumes for Trabecular Bone using 3-D Stereology and FFT Analysis, Trans. 42nd Orthopaedic Research Society Meeting, Feb., 1996, p. 715. 76. Kohn, D.H., Ko, C.C., and Hollister, S.J.: Localized Interface Modeling: Applications Towards Implant Design and Analysis, ASME BED-31, 1995, p. 187-188. 77. Guldberg, R.E. and Hollister, S.J.: Influence of Loading on the Tissue Modulus of Trabecular Bone: A Combined Experimental and Microstructural Modeling Approach, ASME BED-31, 1995, p. 157-158. 78. Flanagan, C.L., Hernandez, M.J. Hollister, S.J. and Taylor, J.E.: A Two-Dimensional Computational Model of Soft Tissue Mechanics using a Stiffening Finite Strain Extremum Principle, ASME BED-31, 1995, p. 101-102. 79. Hollister, S.J. and Caldwell, N.J.: Relationships between Trabecular Tissue Strain and Type I Procollagen Synthesis, Transactions of the 43rd Annual Meeting, Orthopaedic Research Society meeting, p. 589.

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80. Zysset P.K., Goulet R.W. and Hollister S.J.: A Global Relationship between Trabecular Morphology and Homogenized Elastic Properties, Transactions of the 43rd Annual Meeting, Orthopaedic Research Society meeting, p. 64. 81. Guldberg, R.E., Caldwell, N.J., Goulet, R.W., Guo, X.E., Hollister, S.J., Schaffler, M.B., and Goldstein, S.A.: Mechanical Stimulation of Bone Repair: An evaluation of in vivo tissue strains in the hydraulic bone chamber model, Transactions of the 43rd Annual Meeting, Orthopaedic Research Society meeting, p. 1144. 82. Flechtenmacher, J., J. L. Borodkin, S. J. Hollister, and D. K. Dedrick. Tibial Contact Pressure Distributions Following Anterior Cruciate Ligament Transection (Aclt) in Canine Experimental Osteoarthritis (Oa). Arthritis Rheum. 35: S187-S187, 1992. 83. Hollister, S. J., C. C. Ko, and D. H. Kohn. Using Topology Optimization to Predict Bone Properties around Dental Implants. J. Dent. Res. 73: 300-300, 1994. 84. Kohn, D. H., C. C. Ko, and S. J. Hollister. Microstructural Modeling of Dental Implants - Global Results. J. Dent. Res. 73: 300-300, 1994. 85. Kohn, D. H., C. C. Ko, and S. J. Hollister. Experimental Validation of Analytically Determined Interfacial Material Constants. J. Dent. Res. 74: 92-92, 1995. 86. Ko, C. C., D. H. Kohn, S. J. Hollister, and S. A. Goldstein. Comparison between predicted bone strains and measured osseointegration. J. Dent. Res. 75: 483-483, 1996. 87. Bobak, V., R. L. Christiansen, S. J. Hollister, and D. H. Kohn. Finite element analysis of molar-responses to the transpalatal arch. J. Dent. Res. 75: 3350-3350, 1996. 88. Kohn, D. H., S. J. Hollister, and K. E. Healy. Biomimetic strategies to enhance osseointegration. J. Dent. Res. 79: 4, 2000. 89. Borodkin, J.L., Hollister, S.J., Caldwell, N.J., and Kazerooni, A.C.: The Influence of Mechanical Strain Magnitude on Tissue Adaptation to Porous-Coated Implants, BED-Vol 35, ASME Bioengineering Conference, p. 499-500. 90. Hollister, S.J., Levy, R.A., Chu, T-M.G., Halloran, J.W.: Design and Manufacture of an Orbital Floor Scaffold using Image Processing and Rapid Prototyping, BED-Vol 35, ASME Bioengineering Conference, p. 391-392. 91. Zysset, P.K., Marsan, A.L., Chu, T-M.G., Guldberg, R.E., Halloran, J.W., Hollister, S.J.: Rapid Prototyping of Trabecular Bone for Mechanical Testing, BED-Vol 35, ASME Bioengineering Conference, p. 387-388. 92. Charras, G, Hollister, S.J., and Guldberg, R.E.: Accuracy of Digital Image Based Finite Element Methods for Local Trabecular Stresses, Biomedical Engineering Society Meeting, San Diego, CA.

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93. Hollister, S.J., Chu, T.M., Guldberg, R.E., Zysset, P.K., Halloran, J.W., Feinberg, S.E., Levy, R.: 1998, Design and Manufacture of HA Scaffolds for Bone Tissue Engineering, 44th annual meeting, Orthopaedic Research Society, p. 423. 94. Alsberg, E., Hollister, S.J., Taboas, J.M., Lerner, A.L., Moalli, M.R., Bailey, C.J., and Guo, X.E.: 1998, Study of In Vivo Trabecular Bone Adaptation in a Rat Tail Model using Three-Dimensional Micro-Computed Tomography Based Finite Element Technique, 44th annual meeting, Orthopaedic Research Society, p. 554. 95. Guldberg, R.E., Charras, G.T., Foust, R.J., Wilson, R.A., and Hollister, S.J.: Estimating Microstructural Trabecular Bone Strains In Vivo Using Digital Image-Based Finite Element Methods, Cellular Deformation: Mechanics and Mechanisms of Physiological Response Meeting, Emory University October 23-24, 1998. 96. Chu, T.M., Hollister, S.J., Feinberg, S.E., and Halloran, J.W.: Manufacturing of Biomaterial Scaffolds using Image Centered Engineering Methods, Keystone Meeting on Tissue Engineering, Copper Mountain, Colorado, Jan. 10-15, 1998. 97. Chu, T., J. Halloran, and S.J. Hollister. Hydroxyapatite Scaffolds with Controlled Porosity, Annual Meeting of American Ceramic Society. May 3-6, 1998. Cincinnati, OH. 98. Feinberg SE, Hollister SJ, Levy RA, Chu TM, Halloran JW: 1998, “An Image-Based Approach To Design and Manufacture of Biomaterial Scaffolds for Maxillofacial Reconstruction”, XIV Congress of European Association for Cranio-Maxillofacial Surgery, Marina Congress Center, Helsinki, Finland, September 1998 99. McCreadie, B.R. and Hollister, S.J. (1999) “Confocal microscopy based digital finite element models of local strains in and around in situ osteocytes”, Trans. 45th Orthopaedic Research Society Meeting, p. 239 100. Caldwell, NJ., Orton, D.G., Anderson, KC., Moalli, MM., Goldstein, S.A. and Hollister, S.J. (1999) “Trabecular bone adaptation to implant mediated loads”, Trans. 45th Orthopaedic Research Society Meeting, p. 756. 101. Feinberg SE, Hollister SJ, Levy RA, Chu TM, Halloran JW: An Image-Based Approach To Design and Manufacture of Scaffolds for Maxillofacial Reconstruction, 14th International Conference of Oral & Maxillofacial Surgery, Washington, DC, April 26, 1999 102. Taboas, JM,Orton, DG, Chu, TM, Hollister, SJ, 1999, “Biocompatibility of Solid Free Form Fabricated Hydroxyapatite Scaffolds”. Biomaterials Congress 1999, Providence, RI 103. Chu, TM., Halloran, JW, Hollister, SJ, and Feinberg, SE, 1999, “Hydroxyapatite implants by acrylic polymerization”, Annual Meeting of the American Ceramic Society, Indianapolis, IN. April 25-28, 1999

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104. M L Palmer, J A Faulkner, R G Dennis, S J Hollister,"A Hierarchical Model of a Quiescent and Maximally Activated Fiber During Stretch", Biophysical Journal 44th Annual Meeting (2000),Vol 78, p. 333A, 1972-Pos.

105. M L Palmer, S J Hollister, R G Dennis, J A Faulkner,"A Hierarchical Model of a Quiescent and Maximally Activated Fiber During Stretch", Proceedings of the 11th International Conference on Mechanics in Medicine and Biology (2000),p. 7. 106. Feinberg SE, Hollister SJ, Halloran JW, Chu TM, Krebsbach PH: “A Biomimetic Approach To Reconstruction of The Temporomandibular Joint”, Society of Biomaterials, World Congress of Biomaterials, Kamuela, Hawaii, May 18, 2000. 107. Taboas, JM, Orton, DG, Hollister, SJ, Krebsbach, PH, 2000, “Characterization of Porcine Marrow Stromal Cells and Fibroblasts on Collagraft, Gelfoam, and Hydroxyapatite”, 6th World Biomaterials Congress 2000, Kamuela, HI: 108. Taboas, JM, Breymann, LM, Zieg, JA, Orton, DG, Hollister, SJ, Krebsbach, PH, 2000, “Ceramic Pre-Treatment Increases Cell Viability Subsequent to Altered Attachment in Vitro”, 6th World Biomaterials Congress 2000, Kamuela, HI: 109. Feinberg SE, Hollister SJ, Halloran JW, Chu TM, Krebsbach PH: “Biomimetic Approach To Reconstruction of The Temporomandibular Joint”, European Association for Craniomaxillofacial Surgery, Edinburgh, Scotland, September 9, 2000. 110. T.-M.G. Chu, J.W. Halloran, S.J. Hollister, S.E. Feinberg, 2000, "Hydroxyapatite scaffolds with controlled internal architecture" Annual Meeting of the American Ceramic Society, St. Louis, MO. April 25-28, 2000 111. K K Brock, S J Hollister, M L Kessler, D L McShan, L A Dawson, J M Balter (2001) “Characterization of Liver Deformation due to Physiological Movement using Finite Element Analysis”, 43rd Annual Meeting of the American Association of Physicists in Medicine, Salt Lake City, Utah. 112. McCreadie BR, Goldstein SA, Hollister SJ: Strains and fluid flow in and surrounding the osteocyte calculated with poroelasticity and fluid-solid homogenization. ORS 47th Annual Meeting, February 25-28, 2001. 113. Feinberg SE, Hollister SJ, Halloran JW, Chu TM, Krebsbach PH: “Manufactured Scaffolds for Temporomandibular Joint Reconstruction Using Image-Based Engineering”, International Association of Dental Research, Chiba, Japan, June 30, 2001. 114. Hollister, SJ, Chu, TM, Taboas, JM, 2001 “Design optimization of scaffolds for concurrent function and tissue regeneration”, BECON conference on Repairative Medicine: Growing Tissues and Organs, Bethesda, Maryland, June 25-26. 115. Chu, TM, Orton, DG, Hollister, SJ, Halloran, JW, and Feinberg, SE, 2001 “Mechanical and In Vivo Performance of Hydroxyapatite Bone Tissue Engineering

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Scaffolds, BECON conference on Repairative Medicine: Growing Tissues and Organs, Bethesda, Maryland, June 25-26. 116. Taboas, JM., Maddox, RD, Chu, TM, Feinberg, SE, Rutherford, RB, Krebsbach, and Hollister, SJ, 2001, “Designed porous architecture 3D polymeric scaffolds created via SFF fabricated mold casting”, BECON conference on Repairative Medicine: Growing Tissues and Organs, Bethesda, Maryland, June 25-26. 117. Palmer, M., Faulkner, J., Dennis, R., and Hollister, S., 2001, “The etiology of injury in skeletal muscle fibers: large deformation of a non-linear composite with an active stress component”, US National Congress on Computational Mechanics, Dearborn, MI, August 1-4, 2001, p. 510. 118. M L Palmer, J A Faulkner, R G Dennis, S J Hollister,"A Computational Model for Stretch-Induced Injury in Skeletal Muscle", 18th Congress of the International Society of Biomechanics Book of Abstracts (2001),p. 24. 119. Chu, T.M., Hollister, S.J., Flanagan, C., Feinberg, S.E., Fisher, J., and Mikos, A., “Poly(propylene fumarate)/Tricalcium Phosphate Scaffolds with Designed 3D Architecture”, Cold Spring Harbor Laboratory Tissue Engineering Meeting, 2002, p. 14 120. Taboas, J.M., Maddox, R.D., Krebsbach, P.H., and Hollister, S.J. “Osteochondral graft engineering using SFF polymer and ceramic composite scaffolds”, Cold Spring Harbor Laboratory Tissue Engineering Meeting, 2002, p. 35 121. Hollister, S.J., Maddox, R.D., Taboas, J.M., Chu, T.M. “Hierarchical image-based computational scaffold design”, Cold Spring Harbor Laboratory Tissue Engineering Meeting, 2002, p. 46 122. Lin, C.Y., Kikuchi, N. and Hollister, S.J., “Topology optimization of scaffold internal architecture to achieved desired elastic properties and porosity”, Cold Spring Harbor Laboratory Tissue Engineering Meeting, 2002, p. 47 123. Maddox, R.D., Taboas, J.M., Hollister, S.J., and Krebsbach, P.H. “Ex vivo gene therapy induced bone on designed composite scaffolds”, Cold Spring Harbor Laboratory Tissue Engineering Meeting, 2002, p. 63. 124. Lin, C.Y., Kikuchi, N. and Hollister, S.J. “Scaffold internal architecture design for porosity and elastic properties by a topology microstructure optimization method”, Society for Biomaterials meeting, Reno, Nevada, p. 354, 2003. 125. Lin, C.Y., Lin, C.Y. and Hollister, S.J. “An integrated global layout and local microstructure topology optimization approach for spinal cage design and fabrication”, Society for Biomaterials meeting, Reno, Nevada, p. 671, 2003 126. Saito, E., Flanagan, C., Taboas, J.M., Kohn, D.H., Krebsbach, P.H. and Hollister, S.J. “Mechanical and structural properties of designed PLLA, PLGA and PGA scaffolds

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made by indirect solid free-form fabrication”, Society for Biomaterials meeting, Reno, Nevada, p. 35, 2003 127. Taboas, JM, Schek, R.D., Hollister, S.J. and Krebsbach, P.H. “Osteochondral graft engineering using bone marrow stromal cells and SFF polymer and ceramic composite scaffolds”, Society for Biomaterials meeting, Reno, Nevada, p. 121, 2003 128. Maddox, R.D., Carroll, J.W., Hollister, S.J., Mazumder, J., Krebsbach, P.H. “Gene/cell delivery from designed titanium scaffolds made by free-form fabrication”, Society for Biomaterials meeting, Reno, Nevada, p. 33, 2003 129. Diggs, A., Hollister, S.J., and Chu, T.M. “Fabrication and characterization of 3-D biphasic ceramic scaffolds composed of hydroxyapatite and β-tricalcium phosphate”, Society for Biomaterials meeting, Reno, Nevada, p. 353, 2003 130. Chu, T.M., Flanagan, C.L., Hollister, S.J., Feinberg, S.E., Fisher, J.P., and Mikos, A.G. “The mechanical and in vivo performance of 3-D poly(propylene fumarate)/tricalcium phosphate scaffolds”, Society for Biomaterials meeting, Reno, Nevada, p. 660, 2003 131. L. Jongpaiboonkit, T. M. G. Chu, S.J. Hollister, J. W. Halloran 2003: Society of Biomaterials, Title "Characterization and rheology behavior of DCPD cement slips for casting complex scaffold", Society of Biomaterials meeting, Reno, Nevada, 2003. 132. Taboas, J.M., Krebsbach, P.H., Ominsky, M.S., and Hollister, S.J. “Differential regulation of human bone marrow stromal cell mRNA expression in response to substrate ligand and mechanical loading”, Transactions 49th ORS, p. 395, 2003. 133. Maddox, RD, Hollister, SJ, and Krebsbach, PH “Adenoviral vector delivery from sintered hydroxyapatite”, Transactions 49th ORS, p. 914, 2003. 134. Taboas, JM, Hollister, SJ, and Krebsbach, PH “Mechanobiological regulation of human bone marrow stromal cell differentiation”, Doctoral Student Competition, ASME 2003 Summer Bioengineering Conference. 135. Lin, CY, Hsiao, CC, Chen, PQ, and Hollister, SJ, “Mechanical performance of conventional threaded cage designs and interbody fusion cages designed by integrated global and local topology optimization”, Doctoral Student Competition, ASME 2003 Summer Bioengineering Conference. 136. Lin, CY, Kikuchi, N, and Hollister, SJ, “A generalized scaffold internal architecture design method using topology optimization”, Doctoral Student Competition, ASME 2003 Summer Bioengineering Conference. 137. Adachi, T, Tomita, Y and Hollister, SJ “Three-dimensional simulation for porous scaffold degradation and new bone formation in regeneration process”, ASME 2003 Summer Bioengineering Conference.

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138. Schek, RD, Hollister, SJ, and Krebsbach, PH, “Adenoviral vector delivery from sintered hydroxyapatite for bone tissue engineering”, 30th Annual Meeting Controlled Release Society, Scotland., 2003. 139. Schek, RD, Hollister, SJ, and Krebsbach, PH, “Adenoviral vector delivery from hydrogels”, AADR meeting, San Antonio, March 12-15, 2003. 140. Wong DY, Hollister SJ, Krebsbach PH. Effects of Neuronal Induction Media are Specific to Cell Differentiation Potential. Poster presentation at Tissue Engineering Society International Annual Meeting, Orlando, FL, Dec. 2003 141. Lin, C.Y., Mistry, A.S., Shi, X., Mikos, A.G. and Hollister, S.J.: Degradation Properties and Potential Cell-Based Therapy Applications of Poly(Propylene Fumarate)/Beta-Tricalcium Phosphate Spine Interbody Fusion Cages with Topology Optimization Design, Northern Region Congress Asian Pacific Orthopaedic Association (APOA) in conjunction with 3rd Annual Meeting of Pacific Asian Society of Minimally Invasive Spine Surgery, Taipei, Taiwan R.O.C., 2003 142. E.E. Liao, P.H. Krebsbach, and S.J. Hollister, “The Effect of Hyaluronic Acid/Collagen I Composite Gels on Bone*Marrow Stromal Cells and Chondrocytes: a Gel Matrix for Cartilage Regeneration", Tissue Engineering Society, 2004. 143. Saito, E; Flanagan, CL; Taboas, JM; Hollister, SJ; Computational and Experimental Mechanical Propeties of Designed 50/50 PLGA Scaffolds Made by Indirect Solid Free-Form Fabrication, Orthopaedic Research Society, 2004. 144. E.E. Liao, R.M. Schek, P.H. Krebsbach, and S.J. Hollister, "In Vivo Cartilage Formation in SFF Designed PLLA Scaffolds", International Association for Dental Research, Honolulu, 2004. 145. Schek, RM, Hollister, SJ, Krebsbach, PH. Gene Therapy from Composite Solid Free Form Fabricated Scaffolds, Orthopedic Research Society 50th Annual Meeting, 2004. 146. Das S, Adewunmi B, Williams JM, Flanagan CL, Engel A, Hollister SJ, Feinberg S. Mechanical and Structural Properties of Polycaprolactone Scaffolds Made by Selective Laser Sintering. Biomaterials World Congress, 2004. 147. Saito, E; Partee, BI; Das, S; Hollister, SJ; Engineered Wavy Fibered Porous Polycaprolactone Soft Tissue Scaffolds: Design, Fabrication and Mechanical Properties. ORS, 2005 148. L. Jongpaiboonkit, S.J. Hollister, J. W. Halloran "Using micro-computed tomography for complex 3D calcium phosphate scaffold fabricated by indirect solid freeform fabrication", American Ceramic Society, 2005.

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149. L. Jongpaiboonkit, C-Y. Lin, S.J. Hollister, J. W. Halloran, "Elastic behavior of complex 3D ceramics bone tissue scaffolds fabricated by indirect solid freeform fabrication", American Ceramic Society, 2005. 150. L. Jongpaiboonkit, C-Y. Lin, S.J. Hollister, J. W. Halloran Biomaterials Day, Society of Biomaterials, Title "In vivo performance of complex 3D fast-setting calcium phosphate scaffolds fabricated by indirect solid freeform fabrication", Biomaterials Day, Society of Biomaterials, 2005 151. L. Jongpaiboonkit, C-Y. Lin, P.H. Kerbsbach, S.J. Hollister, J. W. Halloran "Elastic behavior of 3D calcium phosphate cement scaffolds fabricated by indirect solid freeform fabrication in vivo", Bioceramics 18, 2005. 152. Saito, E; Liao, EE; Krebsbach, PH; Hollister, SJ; Determination of the effect of pore size on bone formation using controlled pore size PLGA scaffolds loaded with transduced human gingival fibroblasts. International Tissue Engineering Meeting, 2005 153. Wong DY, Gross SC, LaMarca F, Hollister SJ, Krebsbach PH, Nosrat CA. Evaluation of Polymers for Delivery of Cells and Growth Factors for Tissue Engineering and Repair Strategies in the Nervous System, Podium Presentation at Tissue Engineering Society International AnnualMeeting, Oct. 2005 Shanghai PRC. 154. Wong DY, LaMarca F, Hollister SJ, Krebsbach PH. 3-D Culture of Bone Marrow Stromal Cells in Poly- -caprolactone Sponge Affects Neural-Related Gene Expression. Poster presentation at International Society for Stem Cell Research, June 2005, San Francisco, CA. 155. Ali S, Wong DY, Krebsbach PH, Hollister SJ. Optimal Manufacturing of Scaffolds for Spinal Cord Repair. Poster presentation at Midwestern Tissue Engineering Consortium Annual Meeting, April 2005, Cleveland, OH. 156. LaMarca F, Wong DY, Brunner E, Hollister SJ. Preliminary Study of Phenotype Conversion in 3-D Sponge of BMSC to Neural Precursor Cells. Poster presentation at American Association of Neurological Surgeons Annual Meeting, April 2005 New Orleans, LA, 2nd Place Poster. 157. Williams JM, Schek RM, Flanagan CL, Das S, Krebsbach PH, Hollister SJ. In vivo Generation of Bone on Polycaprolactone Scaffolds. Orthopedic Research Society (ORS) 51st Annual Meeting. Poster # 1715, 2005 158. Lin, C.Y., Schek, R.M., Mistry, A.S., Shih, X., Mikos, A.G., Krebsbach, P.H., and Hollister, S.J.: Functional Bone Tissue Engineering Using Ex Vivo Gene Therapy and Topology Optimized, Biodegradable Polymer Composite Scaffolds, 51st Meeting Orthopaedic Research Society, Washington D.C., 2005 159. Lin, C.Y., Wirtz, T., and Hollister, S.J.: Structural and Mechanical Evaluations of A Topology Optimized Titanium Interbody Fusion Cage Fabricated By Selective Laser Melting, 51st Meeting Orthopaedic Research Society, Washington D.C., 2005

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160. Frank La Marca, Kasra Ahmadinia, Barunashish Brahma, Chia-Ying Lin, and Scott J. Hollister: Finite element analysis of an adjacent level strain determined from an in Vivo Spinal fusion model, AANS/CNS Spine Section, Phoenix, 2005. 161. Liao, EE., Krebsbach, PH, and Hollister, SJ, "The effect of composite hyaluronic acid/collagen I gel on chondrocytes in PPF scaffolds in vivo.", International Tissue Engineering Society, Shanghai, China 2005. 162. Barunashish Brahma, Chia-Ying Lin, , Frank LaMarca, , and Scott Hollister. In vivo spinal fusion modelling of spondylolisthesis, American Association of Neurological Surgeons Annual Meeting, San Francisco, 2006 163. Hollister, SJ, Flanagan, CL, Smith, MH, Das S, and Feinberg, SE “Computed Tomography based Degradable Polycaprolactone Scaffold for Temporomandibular Joint Reconstruction”, American Association of Dental Research, Orlando, March 11, 2006. 164. Moffitt, EN, Lin, CY, Kresbsbach, PH, and Hollister SJ “Effect of porosity on bone growth in designed poly(proplyine fumarate)/b-Tricalcium Phosphate Scaffolds”, Orthopaedic Research Society, March 19-22, 2006. 165. Mantila, SM, Williams, JW, Krebsbach, PH, and Hollister SJ “Pore size effects of polycaprolactone scaffolds on in vivo bone tissue engineering”, Orthopaedic Research Society, March 19-22, 2006. COMMITTEE AND ADMINISTRATIVE SERVICE International and National

1996 Technical Advisory Panel, 1996 International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Barcelona, Spain

1997 Scientific Committee Member, 1997 International Union of

Theoretical and Applied Mechanics Symposium on Synthesis in Biosolid Mechanics, Copenhagen, Denmark

1999 Technical Advisory Panel, 4th International Symposium on

Computer Methods in Biomechanics and Biomedical Engineering, Lisbon, Portugal

2001 Technical Advisory Panel, 5th International Symposium on

Computer Methods in Biomechanics and Biomedical Engineering, Rome

2001 Technical Advisory Panel, National Congress on Computational

Mechanics, Dearborn, MI

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2003 Technical Panel, World Technology Evaluation Center,

“Additive/Subtractive Manufacturing R&D”, Evaluating European R&D on Additive/Subtractive Manufacturing, October 18-25, 2003.

2005-06 NSF Technical Panel on Future Advances in Manufacturing –

Organized by WTEC will deliver White Paper on Recommended Funding Programs in Manufacturing

2005-06 Technical Advisory Committee, 7th International Symposium on

Computer Methods in Biomechanics and Biomedical Engineering, Cote d’ Azur, France

2006 Technical Advisory Committee,

University of Michigan 2005- OVPR Conflict of Interest Committee 2005 UM Musculoskeletal Regenerative Medicine Training Grant – Trainee Selection Committee 2005- Biomechanics Curricular Working Group, BME Department 2005 BME Chair Search Committee 2005 Biomedical Engineering Internal Review Committee 2004-2005 Biomedical Engineering ABET committee 2005 Biomedical Engineering Undergraduate Education Committee, Interim Chair 2004 BME faculty search committee 2003- Biomedical Engineering, Undergraduate Education Committee 2000 Diversity Coordinator, Department of Biomedical Engineering

2000 Member, College of Engineering, Ad-Hoc Committee on Advanced Computing

2000 Member, Mechanical Engineering Faculty Search Committee 1999 Member, Curriculum Committee, Department of Biomedical

Engineering, The University of Michigan

1999-2000 Elected member of the College of Engineering Curriculum Committee

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1998-2000 Elected member of Executive Committee, Department of Biomedical

Engineering, The University of Michigan

1999 Member, Curriculum Committee, Department of Biomedical Engineering, The University of Michigan

1998 Chair, Committee on the Biomechanics Curriculum, Department of

Biomedical Engineering, The University of Michigan

1996-1998 Director, Computational Modeling Core, Biomedical Engineering Research Center

1995-1997 Board Member, Biomechanics and Imaging Core, MAC Core 1993-1995 Computer Committee, Department of Surgery 1997 Awards Committee, Department of Biomedical Engineering 1997 Faculty Coordinator for Biomedical Engineering Tech Day

TEACHING ACTIVITIES 2005 BME/ME 456 “Biosolid Mechanics: Modeling and Applications” 2005 BME 332 “Introduction to Biosolid Mechanics 2004 BME/ME 456 “Tissue Mechanics” 2003 On Sabbatical

2002 BME/ME 506 “Computational Modeling of Biological Tissues, Graduate Course

2002 BME/ME 456 “Tissue Mechanics”, Undergraduate/Graduate Course 2001 BME/ME 506 “Computational Modeling of Biological Tissues,

Graduate Course 2001 BME/ME 456 “Tissue Mechanics”, Undergraduate/Graduate Course 2000 BME/ME 506 “Computational Modeling of Biological Tissues,

Graduate Course

2000 BME/ME 456 “Biomechanics”, Undergraduate/Graduate Course

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1999 BME 506 “Computational Modeling of Biological Tissues, Graduate Course

1999 BME/ME 456 “Biomechanics”, Undergraduate/Graduate Course 1998 BME 506 “Computational Modeling of Biological Tissues”,

Department of Biomedical Engineering 1998 Taught ME/BME 456 “Biomechanics”, Undergraduate/Graduate

Course in Biomedical Engineering and Mechanical Engineering and Applied Mechanics

1993 Taught ME 599 "Computational Methods in Biomechanics",

Engineering Graduate Course in Mechanical Engineering and Bioengineering

1991-1996 Lectured on Biomechanics for Orthopaedic Resident Basic Science

Training 1994 Taught ME 350 "Introduction to Finite Element Methods",

Engineering Undergraduate Course in Mechanical Engineering, for the Month of April, 1994.

1991-1994 Taught 3 lectures each year on Bone Mechanics and Adaptation for

Physiology 519 1995 Taught ME350 "Introduction to Finite Element Methods",

Engineering Undergraduate Course in Mechanical Engineering, for one week in October, 1995.

1996 Taught ME 599 "Computational Methods for Tissue Mechanics",

Engineering Graduate Course in Mechanical Engineering and Bioengineering

1996 3 lectures for ME456 "Introduction to Orthopaedic Biomechanics"

on mechanics of fractures fixation and joint mechanics 1996 "Orthopaedic Materials", Lecture at Grace Hospital, October, 1996 1997 "Orthopaedic Materials", Lecture at Grace Hospital, October 1998 1999 "Orthopaedic Materials", Lecture at Mt. Sinai Hospital, August,

1999

GRADUATE STUDENTS MENTORED Ph.D Committee Chair, Mark Palmer, Mechanical Engineering, Graduate, September, 2001

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Ph.D.Committee Chair, Janet Borodkin, Biomedical engineering, Graduated, August, 2000

Ph.D Committee Co-Chair, Juan Taboas, Biomedical Engineering, Graduated, 2004 Ph.D Committee Co-Chair, Rachel Schek, Biomedical Engineering, Graduated 2004 Ph.D Committee Chair, Cheng-Yu Lin, Mechanical Engineering, Graduated 2005 Ph.D Committee Chair, Chia-Ying Lin, Biomedical Engineering, Graduated 2004 Ph.D Committee Chair, Elly Liao, Biomedical Engineering Ph.D Committee Chair, Darice Wong, Biomedical Engineering Ph.D Committee Chair, Alisha Diggs, Biomedical Engineering Ph.D Committee Chair, Eiji Saito, Biomedical Engineering Ph.D Committee Chair, Jessica Williams, Biomedical Engineering Ph.D Committee Chair, Sara Mantila, Biomedical Engineering Ph.D Committee Chair, Heesuk Kang, Biomedical Engineering Ph.D Committee Co-Chair, Barbara McCreadie, Biomedical Engineering, Graduated, 2000 Ph.D. Committee Co-Chair for Ching C. Ko, Thesis Defense in Bioengineering April, 1994.

Ph.D. Committee Co-Chair for Robert E. Guldberg, Thesis Defense in Mechanical Engineering, 1995.

Ph.D. Committee Member for Karl Jepsen, Defense in Bioengineering, January, 1994. Ph.D. Committee Member for Amy Lerner, Mechanical Engineering, Thesis defense in January, 1996. Ph.D. Committee Member for Shine-Chie Cheng, Defense in Mechanical Engineering, April, 1994. Ph.D. Committee Member for Yung Park, Mechanical Engineering

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Ph.D. Committee Member for Hisashi Heguri, Mechanical Engineering, Thesis Defense in 1995. Ph.D. Committee Member for Kenjiro Terada, Mechanical Engineering, Thesis Defense in March, 1996. Ph.D. Committee Member for Jun-Shiou Ou, Mechanical Engineering, Thesis Defense in January, 1996. Ph.D. Committee Member, Traci Wenzel, Bioengineering, Prelim Defense in January, 1995.

Ph.D. Committee Member, Dave Malicky, Mechanical Engineering, Prelim Defense in December, 1995

Ph.D. Committee Member, Mary Frecker, Mechanical Engineering, Defense, March, 1997. Ph.D. Committee Member, Seunjae Min, Mechanical Engineering, Defense, May, 1997.