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Curriculum Vitae Mark S. Slaughter, M.D. Principle Address: Department of Cardiovascular and Thoracic Surgery 201 Abraham Flexner Way, Suite 1200 Louisville, KY 40202 P: 502.588-7600 F: 502.588-7701 [email protected] Current Appointments: Professor of Surgery Chairman Department of Cardiovascular and Thoracic Surgery University of Louisville Louisville, KY 40202 Executive Medical Director Cardiovascular Services Jewish Hospital Louisville, KY 40202 Director, Thoracic Surgery Residency Program University of Louisville Louisville, KY 40202 Director, Heart Transplant and Mechanical Assist Device University of Louisville/Jewish Hospital Louisville, KY 40202 Associate Faculty Bioengineering Department University of Louisville Louisville, KY 40202 Certifications:

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Curriculum Vitae

Mark S. Slaughter, M.D.

Principle Address:

Department of Cardiovascular and Thoracic Surgery

201 Abraham Flexner Way, Suite 1200

Louisville, KY 40202

P: 502.588-7600

F: 502.588-7701

[email protected]

Current Appointments:

Professor of Surgery

Chairman

Department of Cardiovascular and Thoracic Surgery

University of Louisville

Louisville, KY 40202

Executive Medical Director

Cardiovascular Services

Jewish Hospital

Louisville, KY 40202

Director, Thoracic Surgery Residency Program

University of Louisville

Louisville, KY 40202

Director, Heart Transplant and Mechanical Assist Device

University of Louisville/Jewish Hospital

Louisville, KY 40202

Associate Faculty

Bioengineering Department

University of Louisville

Louisville, KY 40202

Certifications:

Mark S. Slaughter, M.D. November 15, 2016

2

Diplomat, National Board of Medical Examiners (#334312) 1987

Diplomat, American Board of Surgery (#37421) 1992

Recertification: (#047360) 2002

Diplomat, American Board of Thoracic Surgery (#5736) 1995

Recertification: (#5736) 2003

Recertification: (#5736) 2013

Licensure:

Illinois, 036-075781 1986

Indiana, 01043482 1995

Kentucky, 42157 2008

Education and Training:

Fellowship

Cardiovascular and Thoracic Surgery 1991-1994

University of Minnesota

University of Minnesota Hospital and Clinic

Minneapolis, MN 55455

Residency

General Surgery 1986-1991

McGaw Medical Center of Northwestern University

Northwestern Memorial Hospital

Chicago, IL 60611

Education

Indiana University School of Medicine 1982-1986

Indianapolis, IN 46202

Purdue University 1978-1982

BS Engineering

West Lafayette, IN 47907

Santa Clara University 1977-1978

Santa Clara, CA 95053

Previous Appointments:

Chair 2014-Present

Department of Cardiovascular and Thoracic Surgery

University of Louisville

Louisville, KY 40202

Professor with Tenure 2014

Department of Cardiovascular and Thoracic Surgery

Mark S. Slaughter, M.D. November 15, 2016

3

University of Louisville

Louisville, KY 40202

Professor of Surgery 2008-Present

Division of Thoracic and Cardiovascular Surgery

University of Louisville

Louisville, KY 40202

Chief 2008-2014

Division of Thoracic and Cardiovascular Surgery

University of Louisville

Louisville, KY 40202

Adjunct Assistant Professor 2007-2008

Department of Physiology and Biophysics

University of Illinois

Chicago, IL 60607

Director Heart Transplantation 2007-2008

Advocate Christ Medical Center

Oak Lawn, IL 60453

President 2001-2008

Cardiac Surgery Clinical Research Center, Inc.

Oak Lawn, IL 60453

Director, Cardiac Transplantation 1996-1998

University of Illinois

Chicago, IL 60607

Director 1998-2008

Cardiac Surgery Research

Advocate Christ Medical Center

Oak Lawn, IL 60453

Clinical Assistant Professor of Surgery 1995-2000

University of Illinois

Chicago, IL 60607

Director 1994-2008

Mechanical Assist Device Program and Surgery

for Congestive Heart Failure

Advocate Christ Medical Center

Oak Lawn, IL 60453

Mark S. Slaughter, M.D. November 15, 2016

4

Cardiothoracic and Vascular Surgical Associates 1994-2008

Advocate Christ Medical Center

Oak Lawn, IL 60453

Honors and Awards:

Department of Cardiovascular and Thoracic Surgery 2015

Teacher of the Year

Business First 2013, 2014

Partners in Health Care

People to Watch

Jewish Hospital & St. Mary’s Hospital Foundation 2011

“Excellence in Education”

ARGI Physician of the Year 2010

Medical News – MediStar Awards

Science Ambassador 2009

Louisville Science Center

Outstanding Physician Leader 2007

Advocate Christ Medical Center

Alley-Sheridan Scholar 1999

Thoracic Surgery Foundation

Understanding the New World of Health Care

Northwestern University 1991

Medical School Outstanding Resident Teacher

Harold L. Method, MD Award 1990

Outstanding Surgical Resident

Northwestern University

Outstanding Surgical Resident 1990

Teacher of the Year

Northwestern University

Academic Achievement Award 1986

Honors Program in Academic Medicine

Indiana University

Senior Elective Honors Program in Surgery 1986

Indiana University

Mark S. Slaughter, M.D. November 15, 2016

5

Summary of Research Productivity:

Grant funding generated as PRINCIPAL INVESTIGATOR = $ 13,710,756

Grant funding generated as CO-INVESTIGATOR = $ 9,780,493

Grant funding TOTAL (PI+CO-I) = $ 23,491,249

Honorary Organizations:

Alpha Omega Alpha

National Honorary Medical Society

Chi Epsilon

Civil Engineering Honor Society

Tau Beta Pi

National Honorary Engineering Society

Vice President

Tau Beta Pi

Purdue University Chapter

Professional Memberships:

American Association of Thoracic Surgeons (AATS)

Education Committee 2013-Present

Ethics Committee 2012-Present

American College of Surgeons

American Heart Association (AHA) 1999-Present

Scientific Statement writing Group 2012

The Importance of Measuring Patient Health Status

CVSA Council 2012-Present

American Medical Association 2011-Present

American Society for Artificial Internal Organs (ASAIO)

Editor in Chief-ASAIO Journal 2013-Present

President 2013-2014

President Elect 2012-2013

Secretary/Treasurer 2011-2012

Program Chair 2011

Mark S. Slaughter, M.D. November 15, 2016

6

Deputy Program Chairman 2009-2010

Executive Committee 2009-Present

Board of Directors 2007-Present

Website Editor 2005-2008

Cardiac Track Annual Meeting Chairman 2006

American Society of Transplant Physicians

American Society of Transplant Surgeons

Heart Failure Society of America

International Society of Heart and Lung Transplantation

Editorial Board 2011-2016

Research Awards Committee 2013-Present

ISHLT MCS Strategy Taskforce 2014-Present

International Society of Rotary Blood Pumps (ISRBP)

President 2013-2014

President Elect 2012-2013

Vice President 2009-2012

Congress Chair, annual Meeting 2011

International Organizing Committee (IFAO/JSAO/ISRBP) 2012

The Society of Thoracic Surgeons (STS)

Network of Experts 2011-Present

STS in collaboration with ACR and ACC 2010

Co-Chair STS University Course on VADs 2008

Abstract Reviewer 2005-Present

STS RUC Five-Year Review Expert Panel 2005

Society of University Surgeons 2013-Present

Southern Thoracic Surgical Association 2008-Present

Councilor at Large 2015-2018

Southern Surgical Association 2011-Present

Professional Service (other):

Kentucky Organ Donor Affiliates (KODA)

Clinical Advisory Committee Member 2009-Present

Association for the Advancement of Medical Instrumentation

Medical Device Particulates Committee 2007-2008

Mechanical Circulatory Support 2007-Present

Device Committee

Mark S. Slaughter, M.D. November 15, 2016

7

American Heart Association

Kentuckiana AHA President 2012-2014

Kentuckiana AHA President Elect 2010-2012

AHA Minority Mentoring System 2008

Mentee: Dr. Juan Carlos Osorio / Columbia University

INTERMACS

Data, Access, Analysis, and Publications (DAAP) 2014-present

Committee Member

UNOS

UNOS – Region 11 2009-2012

Thoracic Review Board

UNOS – Region 7 2006

Thoracic Review Board

CV Member Advisory Council 2007-2008

Gift of Hope Organ & Tissue Donor Network

Kentucky Medical Association (KMA)

Physician Workforce Committee 2011-Present

The Welcome Trust Limited (United Kingdom)

Consultant, Technology Transfer Division 2011

University of Louisville:

Graduate Research Training Faculty as member of 2016-Present

Graduate Faculty of the School of Medicine

University of Louisville 2015-Present

Graduate Faculty, Department of Bioengineering

(Ad Hoc)

University of Louisville 2014-Present

Council of the School of Medicine

University of Louisville 2015-Present

Problem Based Learning

2nd Year Medical Students

University of Louisville Physicians 2014-Present

Board of Directors

University of Louisville 2013

Search Committee

Director Office Technology Transfer

Mark S. Slaughter, M.D. November 15, 2016

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University of Louisville 2012

Search Committee

Vice Dean for Research

University of Louisville Physicians 2011-2013

Executive Committee

Mock Study Section 2011

“Grantseekers”

University of Louisville

Louisville, KY 40202

Radiology 2011

Chair Review Committee

University of Louisville

Oversight Committee 2011-Present

W.H. Coulter Foundation Translational

Research Partners Program Grant

Bioengineering Department

Integrity in Research Review Committee 2011

Hiram C. Polk Surgical Society Member 2010-Present

School of Nursing Committee

Advisory Board Committee 2009-2015

University Physicians Associates 2009-2010

Consolidation Plan Task Force

Government Agency Advisory Committees:

Special Emphasis Panel (SEP) 2011-Present

Peer Review

SBIR Contracts

NIH/NHLBI

Consultant – FDA 2008-Present

Circulatory System Devices Panel

Grant Reviewer 2007

SBIR/STTR National Science Foundation

Health and Human Services 2002-2007

Medicare Coverage Advisory Committee

Mark S. Slaughter, M.D. November 15, 2016

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Physician Reviewer 1999-2008

Illinois Foundation for Quality

Healthcare (Medicare)

Editorial Service:

Editor in Chief

ASAIO Journal 2013-Present

Associate Editor

Annals of Thoracic Surgery 2012-Present

Editorial Board

World Journal of Transplantation 2016-Present

Journal of the American College of Cardiology (JACC) 2012-Present

Senior Consulting Editor JACC Heart Failure

The Journal of Heart and Lung Transplantation (JHLT) 2011-2016

Heart Failure Reviews 2011-Present

Journal of Cardiac Surgery 2011-Present

Cardiac and Vascular Regeneration 1999-2002

Angiogenesis and Myogenesis,

Basic Therapeutic

Journal Reviewer

New England Journal of Medicine (NEJM) 2011-Present

Mayo Clinic Proceedings 2010-Present

Circulation 2008-Present

Congestive Heart Failure 2002-Present

Clinical Committees/Consulting:

1. Oregon Heart 2016

Medical Advisory Board

2. Johnson & Johnson 2015

Heart Failure Technology Group

3. Carmat 2013-Present

Scientific Advisory Board

4. CorMatrix Cardiovascular 2011

Data and Safety Monitoring Board (DSMB)

Consultant

5. SUNSHINE HEART 2010-2016

Scientific Advisory Board

6. REVIVE-IT Trial 2011

Protocol Development Committee Member

Mark S. Slaughter, M.D. November 15, 2016

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7. SCCOR 2010-2012

Medical Management Committee

SCCOR Cell Study

8. External Safety Advisory Board Committee 2009-2011

Data Monitoring Committee (DMC)

Phase II Cardiopulmonary Bypass Surgery Study

Novo Nordisk A/S

9. HeartWare LVAD Trial 2008-2012

National Principle Investigator

10. Novo Nordisk 2009-2011

International Data Safety Monitoring Committee

11. World Heart Corporation 2007-2011

Leavcor ™ Rotary VAD

U.S. Clinical Trial Coordinating Committee

12. Orquis Medical 2007-2008

Exeleras Safety Review Committee

Lake Forest, CA

13. HeartWare, Inc. 2006-2008

Data Safety Monitory board

European Trial

Endowed Lectures/Visiting Professor:

1. Dugan Family Lecturer in Cardiothoracic Surgery, 2nd Annual Dougan Lecture, Oregon

Health Science University, Portland, Oregon, January 22, 2015

2. Kent Trinkle Lecture, Southern Thoracic Surgical Association, Tucson, Arizona,

November 7, 2014.

3. Julian Johnson Lecture, University of Pennsylvania Health System, Philadelphia,

Pennsylvania, May 22, 2014

4. Wilbert J. Keon Endowed Lectureship, University of Ottawa Heart Institute, Ottawa,

Canada,

June 25, 2012.

5. William S. Pierce Endowed Lecture, Sixteenth Annual William S. Pierce Lecture,

Hershey Medical Center, Hershey, PA, May 7, 2012.

Invited Grand Rounds:

1. “The Role of VADs in Advanced Heart Failure and Outpatient Management” Cardiology

Grand Rounds, Central Baptist Hospital, Lexington, KY August 14, 2013.

Mark S. Slaughter, M.D. November 15, 2016

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2. “Trends & Future Role of Mechanical Circulatory Support in Heart Transplantation”,

Methodist J.C. Walter Jr. Transplant Grand Rounds, Methodist Department Surgery,

Houston, TX, October 10, 2012.

3. “Mechanical Circulatory Support: Alternative to Bridge to Transplant.” Cardiothoracic

Grand Rounds, New York-Presbyterian Hospital/Columbia University, New York, NY,

November 18, 2010.

4. “Mechanical Circulatory Support for Advanced Heart Failure: The Rise of the Machine.”

Christ Hospital in Cincinnati Grand Rounds. September 30, 2010.

Invited Lectures:

1. “The Future of Innovation: Collaborative Effort Between Clinicians, Bioengineering and

Industry.” American Heart Association Scientific Sessions, November 14, 2016, New

Orleans, LA.

2. “Unloading Strategies for Myocardial Recovery.” American Heart Association Scientific

Sessions, November 15, 2016, New Orleans, LA.

3. “Developing New Technology to Avoid the Impending Crisis in Heart Transplantation.”

Samuel Gross Lectureship, University of Louisville School of Medicine, November 7,

2016, Louisville, KY.

4. “Ventricular Assist Device Weaning: the impact of pump settings,” European Mechanical

Circulatory Support Summit, November 3, 2016, Berlin, Germany.

5. “Surgical Approaches to Advanced Heart Failure—What’s New?” INOVA Heart &

Vascular Institute, Advanced Heart Failure Symposium, October 21, 2016, Alexandria,

VA.

6. “VAD Therapy Play in the Treatment of Patients with Advanced Heart Failure,”

American College of Cardiology, Kentucky Chapter Annual Meeting, October 8, 2016,

Lexington, KY.

7. “Lessons Learned From Endurance, Roadmap/Medimacs and How To Go Forward”

European Training Symposium, June 24, 2016, Berne, Switzerland.

8. “Hot Topics in VAD Research” ASAIO, June 17, 2016, San Francisco, CA.

9. “Potential Use of HeartMate III and HeartWare MVAD in Children” ASAIO, June 15,

2016, San Francisco, CA.

10. “Extracorporeal Support- the Sooner the Better” AATS May 15, 2016, Baltimore, MD.

Mark S. Slaughter, M.D. November 15, 2016

12

11. “Basic Review of Flow, Shear and Basic MCS design and Subsequent Impact on

Coagulopathies and Other Adverse Events” ISHLT, April 29, 2016 Washington D.C.

12. “Cardiovascular Locum Tenens: Time to Reconsider” Society for Thoracic Surgical

Education, April 21, 2106, Key West, FL.

13. “HVAD Pump Wet Lab” HeartWare Fellows Forum, March 19, 2016 Boston, MA

14. “Mechanical Circulatory Support: Technology Evolution and Overhead of the HVAD

Pump” HeartWare Fellows Forum, March 18, 2016 Boston, MA

15. “Cardiac Mechanical Assist Course for the ICU” Association of Physician Assistants in

Cardiovascular Surgery 35th Annual Meeting, March 13, 2016 Las Vegas, NV.

16. “Advances in VAD Technology: HeartMate III, Heartware MVAD”, Cedars-Sinai Heart

Institute Symposium -An International User’s Guide to Mechanical Circulatory Support,

October 9-10, 2015, Los Angeles, CA.

17. “Alternative Surgical Techniques for Implantation, Exchange and Explanation in Long

Term LVADS” International Society for Heart and Lung Transplantation, April 14,

2015, Nice, France.

18. “Mechanical Circulatory Support Patient Selection: Changing Paradigms, Less Ill

Patients for LVAD Therapy” 8th Branislav Radovancevic International Symposium for

Innovations and New Treatment Strategies in Heart Failure, September 24, 2015,

Budapest, Hungary

19. “Current Topics in Regeneration Medicine in End Stage Heart Failure”, 45th Annual

Japanese Society for Cardiovascular Surgery, February 15, 2015, Kyoto, Japan.

20. “Myocardial Recovery; Fact, Fiction and Future Directions” European Association for

Cardio-Thoracic Surgery, November 11th-14th, 2014, London, England.

21. “What is Important to Know About LVAD Therapy” 2nd Annual European Training

Symposium, June 27th-28th, 2014, Berne, Switzerland.

22. “What’s New in LVAD: Hemolysis and Thrombosis” 2nd Annual European Training

Symposium, June 27th-28th, 2014, Berne, Switzerland.

23. “Do We Need Physiologic VAD Control And Flow Estimation For Improved Patient

Care?” ASAIO 60th Annual Conference, June 18th – 21st, 2014, Washington, DC.

24. “Wrong Pump, Wrong Time” ASAIO 60th Annual Conference, June 18th – 21st, 2014,

Washington, DC.

25. “Surgical Approaches in Post-Op Care” ASAIO 60th Annual Conference, June 18th – 21st,

2014, Washington, DC.

Mark S. Slaughter, M.D. November 15, 2016

13

26. “Live in a Box, How I Do It: New Innovations in LVAD Therapy” ISMICS Master’s Day

Program, May 27th – 28th, 2014, Boston, Massachusetts.

27. “HeartWare MVAD and TMVAD” ISMICS Master’s Day Program, May 27th – 28th,

2014, Boston, Massachusetts.

28. “Risk Factors for Adverse Outcomes with HeartWare HVAD” INTERMACS 8th Annual

Meeting, May 4th – 5th, 2014, Arlington, Virginia.

29. “Matching Pumps to Patients: Considerations for Device Type, Type of Flow Based

Upon Patient Factors” 94th Annual AATS Meeting, April 25th – 29th, 2014, Toronto,

Canada.

30. “Research and Technology Advisory Group (RTAG) and CIRI” CVSL April Quarterly

Meeting April 21st-23rd, 2014, Naples, Florida.

31. “Myocardial Regeneration and Recovery with Extracellular Matrix and LVAD Support”.

34th Annual ISHLT Meeting. April 13, 2014.

32. “Early Post-op anticoagulations: Is It Needed and What to Use?” 34th Annual ISHLT

meeting. April 10, 2014, San Diego, CA.

33. “HeartWare” Small group Session ISHLT Academy MCS Meeting pre 34th Annual

ISHLT Meeting. April 8th, 2014. San Diego CA

34. “Tailoring Pumps to Patients” Surgical Considerations- ISHLT Academy MCS Meeting-

34th Annual ISHLT Meeting. April 7th, 2014. San Diego CA

35. “Left Ventricular and Vascular Biomechanics in Advanced Heart Failure Patients

Supported by Continuous and Pulsatile Left Ventricular Assist Devices”, Quick Shot

Presentation at Academic Surgical Congress 2014 9th Annual Meeting, San Diego, CA,

Feb 4th, 2014-Presented by Dr. Allen Cheng.

36. “CARMAT Bioprosthetic Hydraulic Total Artificial Heart”. STS/AATS Tech Con 2014

Annual Meeting January 26, 2014. Orlando, FL

37. “Surgical Tribulations of a Heart Failure Patient: VAD + Transplant” Case Theatre

Presentation, AHA Scientific Sessions 2013 Annual Meeting. Dallas, TX, November 18,

2013

38. “State of the Art LVADs”, Leading the Round Table Discussion: TV Studio at EACTS

Annual Meeting, Vienna, Austria. October 8, 2013.

39. “Long Term Circulatory Support with Rotary Blood Pumps: Is it worthwhile?”

Discussant at EACTS Annual Meeting, Vienna, Austria. October 8, 2013.

Mark S. Slaughter, M.D. November 15, 2016

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40. “Destination Life on Device”, Key Note Speaker -Symposium Heart 4: ISRBP 2013

Annual Meeting, Yokohama Japan, September 28, 2013

41. “Less Invasive Surgery of RBPs” ISRBP 2013 Annual Meeting, Yokohama, Japan.

September 27, 2013.

42. “Current International Status of RBP: Clinical Results of Long Term Support with RBP”.

ISRBP Annual Meeting, Yokohama, Japan. September 26, 2013.

43. “Expanding Indications for LVADs from Support to Cell-Based Therapies” Greater

Milwaukee Heart Failure Society, Aurora St. Luke’s Medical Center. August 19, 2013.

44. “Device Options for Severe Biventricular Failure”, Comprehensive Advanced Heart

Failure Summit, Vanderbilt Heart and Vascular Institute, Vanderbilt University,

Nashville, TN. August 10, 2013.

45. “Centrifugal Flow Physiology: Technical and Clinical Implications, Data Update, and

Strategies to Improve Outcomes”, HeartWare HVAD Clinician Forum. Toronto, Ontario,

CAN, July 27, 2013.

46. “What are the Clinical Contraindications to Destination Therapy in the Current Era?”

Gordon Research Conference 2013, Renaissance Tuscany, Lucca (Barga), Italy. June 26,

2013.

47. General Session 2: Co-Chair, American Society for Artificial Internal Organs 2013 59th

Annual Meeting. Chicago, IL, June 14, 2013.

48. “The Future of VAD Therapy”, American Society for Artificial Internal Organs 2013 59th

Annual Meeting, VAD Coordinator Session 2. Chicago, IL, June 14, 2013.

49. “Continuous Flow Pumps” Co-Chair Moderator, American Society for Artificial Internal

Organs 2013 59th Annual Meeting, Chicago, IL, June 13, 2013.

50. “The Future of Mechanical Circulatory Support”, American Society for Artificial Internal

Organs 2013 59th Annual Meeting, General Session 1: Measuring Success: Medical

Devices & Organ Failure. Chicago, IL, June 13, 2013.

51. “Implantation of Latest Generation Ventricular Assist Devices”, American Association

for Thoracic Surgery 2013 Adult Cardiac Skills and Decision Making Course,

Minneapolis, MN, May 4, 2013.

52. “JHLT at the ISHLT: The Year in a Capsule Discussion: Highlights of Heart

Transplantation and Mechanical Circulation” ISHLT 33rd Annual Meeting, Montreal,

Canada. April 26, 2013.

53. “Matching Pumps to Patients: Considerations for Device Type & Type of Flow Based

Upon Patient Factors”. ISHLT 33rd Annual Meeting, Montreal, Canada. April 23, 2013.

Mark S. Slaughter, M.D. November 15, 2016

15

54. “Alternative Techniques for LVAD Implantation” Annual Society of Thoracic Surgical

Education Meeting. Walland, Tennessee, April 20th, 2013.

55. “Marginal Donors for Heart Transplantation: What are they and Does it Matter?” Annual

Society of Thoracic Surgical Education Meeting. Walland, Tennessee, April 19th, 2013.

56. “Heart Failure: Cells to LVADs”, Big East Cardiovascular Symposium, Clinical

Research: The Cornerstone of Future Treatments for Cardiovascular Disease. New

York, NY, March 15th, 2013.

57. “SBIR: A More Viable NIH Grant Option?”, SBIR/AATS Workshop, Bethesda,

Maryland. March 8th, 2013.

58. “What Will the VAD World Look Like in 3 - 5 Years?” The Society of Thoracic

Surgeons 49th Annual Meeting, Los Angeles, CA, January 29, 2013.

59. “ADVANCE Trial Update”, The Society of Thoracic Surgeons 49th Annual Meeting, Los

Angeles, CA, January 29, 2013.

60. “Does the type of unloading device (pulsatile, continuous, counterpulsatile) matter?”

Utah Cardiac Recovery Symposium, Salt Lake City, UT, January 19, 2013.

61. “Destination VADS Should Only Be Done In A Transplant Center (Con Position)”,

Southern Thoracic Surgical Association, Naples, FL, November 8, 2012.

62. “Generation Skipping: VADs, Valves and Devices”, American Heart Association 2012

Scientific Sessions, Los Angeles, CA, November 7, 2012.

63. “Recovery Is Real: Management Tactics and Operative Techniques”, American Heart

Association 2012 Scientific Sessions, Los Angeles, CA, November 6, 2012.

64. “Transapical LVAD Implantation”, 26th European Association for Cardio-Thoracic

Surgery Annual Meeting, Barcelona, Spain, October 27, 2012.

65. “Should Patients on Long Term ‘Destination Therapy’ be Listed for Transplant? Under

What Condition and What Status?”, 15th Heart Failure Summit: 21st Century Treatment

of Heart Failure: Synchronizing Surgical and Medical Therapies for Better Outcomes”,

Cleveland, OH, October 19, 2012.

66. “Cost of Implant, Comparators and Effectiveness”, VAD Economic Summit, Dallas, TX,

September 27, 2012.

67. “Mechanical Circulatory Support for End-Stage HF: When it is Too Late to Implant a

RBP?”, 20th Congress of the International Society for Rotary Blood Pumps (ISRBP),

Istanbul, Turkey, September 20, 2012.

Mark S. Slaughter, M.D. November 15, 2016

16

68. “Short-Term Device Strategies for Acute Cardiac Failure: What to Do When Medications

Fail?” Heart Failure Society of America (HFSA) Annual Scientific Meeting, Seattle, WA,

September 9, 2012.

69. “VAD Destination Trials”, 4th Alfred ICU International Symposium on ECMO & VAD

Support in Critical Care, Melbourne, AU, July 19, 2012.

70. “Marginal Cardiac Donors”, 4th Alfred ICU International Symposium on ECMO & VAD

Support in Critical Care, Melbourne, AU, July 18, 2012.

71. “Fine Tuning Pumps”, 32nd Annual Meeting of the International Society of Heart & Lung

Transplantation, Prague, Czech Republic, April 18, 2012.

72. “Matching Pumps to Patients”, 32nd Annual Meeting of the International Society of Heart

& Lung Transplantation, Prague, Czech Republic, April 17, 2012.

73. “The Failing Heart - Update in Device Therapy”, Cardiology Colloquium, Kettering CV

Institute, Wright State University School of Medicine, Dayton, OH February 29, 2012.

74. “HeartWare: Results of the ADVANCE Bridge to Transplant Trial.” EACTS

Meeting, Lisbon, Portugal, October 2, 2011.

75. “Controversial Issues in heart Failure Device Treatment.” “Brano” Heart Failure

Forum, Belgrade, Serbia, October 1, 2011.

76. “Historical Development of Mechanical Circulatory Support.” NY State Chapter of

the American College of Cardiology, Rochester, NY, September 24, 2011.

77. “Needs for RVAD: None, Temporary or Permanent.” HFSA, Boston, MA,

September 21, 2011.

78. “Pre-Clinical Reliability Testing.” STS/FDA VAD Symposium, Washington, D.C.,

September 16, 2011.

79. “What Is The Lower Limit of Anticoagulation Necessary For The Current Generation of

Durable MCS Devices?” ISHLT Annual Meeting, San Diego, CA, April 16, 2011.

80. “Cardiovascular Disease in Kentucky.” Jewish Hospital Foundation Board of Directors,

Louisville, KY, April 11, 2011.

81. “Bridges and Destinations: Ventricular Assist Devices in the Current Era.” ACC Annual

Scientific Session, New Orleans, LA, April 5, 2011.

82. “Should Status 1B Patients With a VAD Be Transplant?” Texas Heart Institute Annual

Summit Meeting, Houston, TX, March 12, 2011.

83. “Cardiovascular Disease in Kentucky.” Rotary Club, Louisville, KY, February 24, 2011.

Mark S. Slaughter, M.D. November 15, 2016

17

84. “Historical Development of Mechanical Circulatory Support.” Optimal Treatment

Strategies for Advanced Heart Failure, Mayo Clinic, Scottsdale, AZ, February 12, 2011.

85. “Destination Therapy: The New Paradigm.” Optimal Treatment Strategies for Advanced

Heart Failure, Mayo Clinic, Scottsdale, AZ, February 12, 2011.

86. “Management of Anticoagulation Following Ventricular Assist Device Placement.” 8th

Vail Cardiothoracic Transplantation An International Update, Vail, CO, January 24,

2011.

87. “New Trends and Indications in LVAD Support.” Southern Thoracic Surgical

Association, Lake Buena Vista, FL, November 4, 2010.

88. “Heart Transplant vs. Left Ventricular Assist Device (LVAD) in Heart Transplant

Eligible Patients.” Southern Thoracic Surgical Association, Lake Buena Vista, FL,

November 6, 2010.

89. “Advanced Heart Failure Treated with Continuous Flow Left Ventricular Assist

Device.” American Heart Association Scientific Sessions 2010, Chicago, IL,

November 14, 2010.

90. “Extracorporeal Devices.” American Heart Association Scientific Sessions 2010,

Chicago, IL, November 14, 2010.

91. “ECMO Support Moderator. First International Congress on ECMO Therapy in

Cooperation with ASAIO.” Harrisburg, PA. May 26, 2010

92. “Current Economics and Regionalization for VAD Therapy in Advanced Heart

Failure.” Society for Thoracic Surgical Education. Sedona, AZ. March 12, 2010.

93. “Expanding the number of VAD centers: Problems and Pitfalls.” Texas Heart

Institute Symposium. Houston, TX; March 6, 2010.

94. “Advances in Patient Outcomes.” Thoratec Destination Life: Advanced Heart

Failure Therapy in the New Era. Chandler, AZ; February 20, 2010.

95. “VAD Update – Thoratec: HeartMate II.” European Mechanical Support Summit.

Paris, France; December 3, 2009.

96. “Surgical Management of Driveline and Pocket Infection”. The Harefield VAD

Clinical Management Course, Denham, UK; October 4, 2009.

97. “Device Selection: Clinical Aspects.” The Harefield VAD Clinical Management

Course, Denham, UK; October 3, 2009.

Mark S. Slaughter, M.D. November 15, 2016

18

98. “Surgical Technique: Long Term Devices.” The Harefield VAD Clinical

Management Course, Denham, UK; October 3, 2009.

99. “Is Mechanical Circulatory Support Going to be Limited to Large Transplant

Centers?” Thoratec Economic Summit, Dallas TX; October 1, 2009.

100. “Do Patients Require Replacement of the Entire Circulation? The potential for

Partial Circulatory Support.” Heart Failure Society of America, Boston, MA;

September 15, 2009.

101. “Partial vs. Full MCS for Cardiogenic Shock.” Gordon Research Conference,

Waterville Valley, NH; September 8, 2009.

102. “What Have We Learned About Continuous Flow Pumps?” Cardiovascular

Care: Legacy and Innovation, Cleveland, OH; June 4, 2009.

103. “FORCEfield”™ Novel Technology for Surface Treatment of Mechanical Heart

Valves for Inhibition of Platelet Adhesion.” ACTS 2009, New York, NY; May 6,

2009.

104. “Mechanical Circulatory Support: The Future for End-Stage Heart Failure.” 21st

Century Treatment of Heart Failure: Utilizing Medical and Surgical Therapies for

Optimal Outcomes Symposium, Louisville, KY; April 16, 2009.

105. “Heart Pumps: Current and Future Technologies for Cardiovascular Support.” 3rd

Annual Cardiovascular System Symposium, Louisville, KY; March 5, 2009.

106. “Long-Term Mechanical Support: What is the Next Step?” The American

Academy of Cardiovascular Perfusion, Dallas, TX; February 7, 2009.

107. “Mechanical Circulatory Support: The Future for End-Stage Heart Failure.”

Grand Rounds. St. Mary’s Hospital, Evansville, IN; February 4, 2009.

108. “Contemporary Experience with New Pumps – HeartWare.” Cleveland Clinic

21st Century Treatment of Heart Failure, Cleveland, OH; October 18, 2008.

109. “Design Concepts and Initial Tests of a Prototype Mechanical Circulatory

Support Device from HeartWare.” ISRBP Meeting, Houston, TX; October 3, 2008.

110. “New Surface Treatment of Mechanical Heart Valves.” EACTS Meeting,

Lisbon, Portugal; September 13, 2008.

111. “Echocardiography: A Vital Tool for the Appropriate Use of Ventricular Assist

Devices.” Echo Society Meeting, Lincolnshire, IL; July 2, 2008.

112. “Mechanical Circulatory Support for End Stage CHF.” University of California

San Francisco, San Francisco, CA; June 19, 2008.

Mark S. Slaughter, M.D. November 15, 2016

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113. “Mechanical Circulatory Support for Advanced Heart Failure.” Elkhart General

Hospital, CME Event, Elkhart, IN; June 11, 2008.

114. “Surgical Approaches to End-Stage Heart Failure.” Grand Rounds. Hartford, CT;

June 5, 2008.

115. “Bleeding takes Center Stage: Strategies to decrease bleeding during implant and

transplant.” BTMCS 2008, Vienna, Austria; May 17, 2008.

116. “State of the Art Anticoagulation Regimens in MCS.” BTMCS 2008, Vienna,

Austria; May 17, 2008.

117. “Mechanical Circulatory Support for Advanced Heart Failure.” Cardiovascular

Symposium, Community Hospital, Munster, IN; April 19, 2008.

118. “Current Outcomes in Destination Therapy.” ISHLT 28th Annual Meeting and

Scientific Sessions, Boston, MA; April 9, 2008.

119. “Partial Assist Pumps.” Texas Heart Institute, Rodeo Meeting, Houston, TX;

March 7-8, 2008.

120. “Mechanical Circulatory Support for Congestive Heart Failure.” Grand Rounds,

University of Louisville, Louisville, KY; February 27, 2008.

121. “Device Update on HeartMate II.” EUMS – 2nd European Mechanical

Circulatory Support Summit, Paris, France; November 30, 2007.

122. “Permanent Mechanical Circulatory Support Vs. Transplantation: Is the

Difference Real or Artificial?” 21st Century Treatment of Heart Failure:

Synchronizing Surgical and Medical Therapies for Better Outcomes,

AATS/ACC/Cleveland Clinic, Cleveland, OH; October 20, 2007.

123. “The Future of Mechanical Support: Destination Therapy, Where are We?”

CCTSS/ISPS 2008 Meeting, Advocate Christ Medical Center, Oak Lawn, IL;

October 13, 2007.

124. “Transplantation and Mechanical Circulatory Support for End-Stage CHF.”

Grand Rounds, Memorial Hospital, South Bend, IN; September 26, 2007.

125. “Destination Therapy: The New Frontier in the Treatment of End-Stage Heart

Failure.” Munster Community Hospital, Munster, IN; September 6, 2007.

126. “Mechanical Circulatory Support for Advanced Heart Failure.” Grand Rounds,

Munster Community Hospital, Munster, IN; June 27, 2007.

Mark S. Slaughter, M.D. November 15, 2016

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127. “Regulatory Issues Surrounding Heart Failure Devices.” HFSA, Bethesda, MD;

May 31-June 1, 2007.

128. “Anticoagulation Management Issues with Axial Flow Devices: HeartMate II.”

ISHLT, San Francisco, CA; April 25-28, 2007.

129. “Building a Destination Therapy Practice.” ISHLT, San Francisco, CA; April 25-

28, 2007.

130. “A Congestive Heart Failure Survey of Illinois Physicians: What Do They Know

That We Don’t?” Texas Heart Institute, Houston, TX; March 2-3, 2007.

131. “Destination Therapy: Current Outcomes and Future Hurdles.” Advocate Illinois

Masonic Medical Center, Chicago, IL; February 3, 2007.

132. “Mechanical Assist Circulatory Support for Patients with End Stage Heart

Failure.” St. Catherine Hospital, East Chicago, IN; January 18, 2007.

133. “Destination Therapy Improved Outcomes with HeartMate II LVAD.” European

Mechanical Circulatory Support Summit, Bad Oeynhausen, Germany; December 6-

9, 2006.

134. “Long Term Use for Mechanical Assist Device Support: Updates and Current

Outcomes.” Grand Rounds, Advocate Christ Medical Center, Oak Lawn, IL;

October 5, 2006.

135. “Mechanical Heart Replacement: Ready for Prime Time.” Midwest Heart

Foundation, Congestive Heart Failure Symposium, Lake Geneva, WI; September

15-16, 2006.

136. “Reducing Emboli in Cardiac Surgery: Does it Make a Difference?” 16th World

Congress of the World Society of Cardiothoracic Surgeons, Ottawa, Canada; August 19,

2006.

137. “Ventricular Assist Device Support and Myocardial Recovery.” Specialty Review in

Pediatric Cardiology, Chicago, IL; August 19, 2006.

138. “The Ideal Control System for Mechanical Blood Pumps.” ASAIO; June 10, 2006.

139. “Mechanical Circulatory Support: Current Indications & New Devices.” Grand

Rounds, Lancaster, PA; February 28, 2006.

140. “VAD Destination Therapy is Ready for Prime Time.” STS/AATS Tech Con,

Chicago, IL; January 28, 2006.

141. “LVAD’s for Permanent Use: Surgical Therapy for End-Stage CHF.” 9th Annual

Mark S. Slaughter, M.D. November 15, 2016

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Update in Cardiovascular Disease: Advances in the Management of Congestive Heart

Failure, Oak Brook, IL; October 29, 2005.

142. “Ventricular Assist Devices.” 10th Annual Illinois State Perfusion Society Meeting,

Loyola University, Chicago, IL; October 8, 2005

143. “Contemporary Outcomes with Mechanical Circulatory Support Devices and

Economic Implications.” Heart Failure Society of America, Boca Raton, FL; September

18, 2005.

144. “Surgical Therapies for Heart Failure.” 12th Annual Cardiovascular Symposium at

Eagle Ridge Conference Center, Galena, IL; September 10, 2005.

145. “Surgical Therapies for Heart Failure.” 4th Annual Deep in the Heart of Texas-

Congestive Heart Failure Symposium, San Antonio, TX; February 5, 2005.

146. “Where are the DT Patients? Why Aren’t We Seeing Them? What Can We Do?”

Building a Successful Destination Therapy Program, Tampa, FL; January 23, 2005.

147. “Destination Therapy: Current Outcomes.” Lutheran General Cardiology Grand

Rounds, Park Ridge, IL; November 2, 2004.

148. “Can We Push the Envelope on Home Discharge?” The Heart of the

Matter: Improving Clinical Outcomes for Patients with End-Stage Heart Failure

Symposium, Hollywood, FL; October 21-23, 2004.

149. “Debate: DT is ready for Prime Time.” The Heart of the Matter: Improving Clinical

Outcomes for Patients with End-Stage Heart Failure Symposium, Hollywood, FL;

October 21-23, 2004.

150. “Educating Our Referral Sources about Destination Therapy.” Current Strategies in

Heart Failure Management: Drugs to Devices. Louisville, KY; August 27-29, 2004.

151. “Destination Therapy: Past, Present and Future.” Upstate New York Heart Failure

Symposium, Rochester, NY; May 1, 2004.

152. “Converge Medical Distal Sutureless Anastomotic System.” FDA Panel Presentation,

Washington, DC; March 18, 2004.

153. “Surgical Alternatives to Heart Failure.” Congestive Heart Failure: Innovations in

Medical & Surgical Therapy, Chicago, IL; February 21, 2004.

154. “Home Discharge with Thoratec TLC-II.” Thoratec Worldwide Sales Meeting,

Phoenix, AZ; January 18-22, 2004.

155. “Destination Therapy: Current Results and Future Hurdles.” Thoratec Worldwide

Sales Meeting, Phoenix, AZ; January 18-22, 2004.

Mark S. Slaughter, M.D. November 15, 2016

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156. “Ventricular Assist Device (VAD) for End Stage Heart Failure.” Advocate Christ

Medical Center Nursing Grand Rounds. Oak Lawn, IL; December 2, 2003.

157. “LVADs & Destination Therapy: Has the Future Arrived?” Advanced Strategies in

the Treatment & Management of Heart Failure, Philadelphia, PA; November 22, 2003.

158. PTCA vs. Surgical Revascularization in Young Adults.” 5th International Congress on

CAD, Florence, Italy; October 19-22, 2003.

159. “Robotic Mitral Valve Repair: Improved Results and Patient Satisfaction.” 3rd World

Congress on Heart Disease-New Trends in Research, Diagnosis and Treatment,

Washington, DC; July 12-15, 2003.

160. “Permanent Mechanical Assist Device Support.” European Society of Cardiology,

International Society for Heart Research Symposium. Heart Failure 2003, Strasbourg,

France; June 21, 2003.

161. “Single Center Results of the Thoratec VAD TLC-II System: Outpatient Experience.”

Illinois State Perfusion Society, Oak Lawn, IL; April 12th, 2003.

162. Surgical Treatment of Congestive Heart Failure.” ISPS, Oak Lawn, IL; April 12th,

2003.

163. Surgical Therapies for Heart Failure: LVADs, Restraint and Beyond.” CME activity

for Heart Failure Update 2003, Oakbrook Terrace, IL; February 12, 2003.

164. “Robotic Mitral Valve Repair Surgery with the daVinci™.” Surgical System

Symposium, Chicago, IL; November 21, 2002.

165. “Bridge to Recovery: Alternative to Cardiac Transplantation?” Mechanical Assist

Device Support for Advanced Heart Failure: Has the Future Arrived? Chicago, IL;

November 16, 2002.

166. “Mechanical Complications of Acute Myocardial Infarction.” Grand Rounds, Christ

Hospital and Medical Center, Oak Lawn, IL, September 12, 2002.

167. “Ventricular Assist Device Support: New Indications and Patient Management.”

Grand Rounds, Maine Medical Center, Portland, ME; August 29, 2002.

168. “Skinned Myocyte Contractile Function in Patients with LV Dysfunction: Predictor of

Myocardial Recovery.” 8th World Congress on Heart Failure- Mechanisms and

Management, Washington, DC; July 14, 2002.

169. “TLC-II Home Discharge Trial.” Thoratec Corporation Investigators and Users

Meeting, Scottsdale, AZ; May 17, 2002.

Mark S. Slaughter, M.D. November 15, 2016

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170. “Coronary Artery Bypass Grafting vs. Stenting for Multi-Vessel CAD.” Grand

Rounds, Christ Hospital & Medical Center, Oak Lawn, IL; January 25, 2001.

171. Preliminary Experience with a New Synthetic Coronary Artery Bypass Graft (ARIA).”

New Era Cardiac Surgery, Laguna Niguel, CA; January 7, 2001.

172. “Thoratec LVAD Insertion and Patient Management.” Baylor College of Medicine,

Dallas, TX; November 4, 2000.

173. “Left Ventricular Mechanical Assist & Myocardial Recovery.” Chicago Educational

Symposium, Chicago, IL; October 12, 2000.

174. “Steroids and the Systemic Inflammatory Response of Cardiopulmonary Bypass.”

Illinois State Perfusion Society 2000 Annual Meeting, Oak Lawn, IL; March 4, 2000.

175. “The Effect of the New UNOS Listing Criteria on Patients with Mechanical Assist

Devices at Non-Transplant Programs.” HeartMate Investigators and Users Meeting;

Tampa, FL; October 26, 1999.

176. “LVAD for Myocardial Recovery in Dilated Cardiomyopathy.” The Dr. Arfan Al-

Hani Cardiology Symposium, St. James Hospital, Chicago Heights, IL; October 16,

1999.

177. “Use of LVAD for Planned Bridge to Recovery. An alternative to Cardiac

Transplantation.” VAD Symposium, Los Angeles, CA; September 18, 1999.

178. “Improved Clinical Utility: The Thoratec VAD System.” Thoratec VAD Symposium,

Chicago, IL; June 19, 1999.

179. “The Changing Donor and its Effect on Thoracic Organ Procurement.” UNOS Region

7 Forum, Chicago, IL, April 8, 1999.

180. “Hemodynamic Management of the Thoracic Organ Donor.” ROBI (Regional Organ

Bank of Illinois), Chicago, IL; October 19, 1998.

181. “Surgical Therapy for Congestive Heart Failure.” Bloomington Hospital,

Bloomington, IN; April 10, 1998.

182. “Current Surgical Therapy for End-Stage Heart Failure.” Midwest Clinical

Conference, Chicago, IL; February 20, 1998.

183. “HeartMate: Indications and Outcomes of Left Ventricular Assist.” Grand Rounds,

Christ Hospital and Medical Center, Oak Lawn, IL; December 4, 1997.

184. “Left Ventricular Assist Devices: Bridge to Transplantation and Beyond.” The

Chicago Summer Educational Symposium, Chicago, IL; August 28, 1997.

Mark S. Slaughter, M.D. November 15, 2016

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185. “Cardiac Transplantation: Current Indications and Outcomes.” Grand Rounds,

University of Illinois, Chicago, IL; January 2, 1997.

Medical School/Students Lectures:

1. “Biomedical Device Design: From Bench to Bedside,” University of Louisville School of

Medicine, Louisville, KY, September 2, 2016.

2. “Mechanical Circulatory Support for Heart Failure: Where are we and what is in the

Future?” University of Louisville, Cardiology Grand Rounds, Louisville, KY; January

18, 2012.

3. “New Frontiers in Cardiothoracic Surgery: The Role of Left Ventricular Assist

Devices in the Treatment of Heart Failure.” University of Louisville Bench to

Bedside Lecture, Louisville, KY; June 21, 2011.

4. “Current Treatments for Advanced Heart Failure: The Dawn of a New Era.” Jewish

Hospital Heart and Lung Institute “The Louisville Heart Failure Forum,” Louisville, KY,

June 17, 2011.

5. “Adult ECMO for ARDS.” Grand Rounds, Department of Surgery, University of

Louisville, Louisville, KY, April 8, 2011.

6. “Recent Advances in Mechanical Circulatory Support and Research Opportunities for

Medical Students.” Freshman/Sophomore Surgical Club Dinner, The Olmsted,

Louisville, KY, March 22, 2011.

7. “The Rise of the Machine: Iterative Engineering in LVADs.” University of

Louisville Bench to Bedside Lecture. Louisville, Ky. July 1, 2010.

8. “Mechanical Circulatory Support for Advanced Heart Failure: The Rise of the

Machine.” University of Louisville Cardiovascular Medicine Grand Rounds.

Louisville, KY; January 13, 2010.

9. “Managing the Pulseless Patient.” Pulmonary/Critical Care Grand Rounds.

University of Louisville, Louisville, KY; October 30, 2009.

10. “Mechanical Heart Pumps are the Future of Heart Failure.” Glefand Invited

Lecture. Phi Delta Epsilon, Louisville, KY; December 10, 2008.

11. “Surgical Therapy for End-Stage Lung Disease: Transplant to Artificial Lungs.”

Pulmonary Division, University of Louisville, Louisville, KY; November 25, 2008.

12. “Mechanical Circulatory Support: The Future for End-Stage Heart Failure.”

University of Louisville Department of Surgery Grand Rounds, Louisville, KY;

October 10, 2008.

Mark S. Slaughter, M.D. November 15, 2016

25

Grant Support:

Pending:

OGMB140654

(PI: Slaughter)

Genetic Risk Factors of Sudden Cardiac Death in African Americans

$54,468

Active:

R44HLxxxxxx-01 (PI: Slaughter & Soucy)

9/1/2014-8/31/2017

NIH SBIR phase I-II Grant (*Submitted 12/5/2013)

$1,721,033

Development of P-ECM Intra-Myocardial Delivery System for Heart Failure Therapy

R44HLxxxxxx-01 (PI: Slaughter & Koenig) 5/1/2014-4/30/2017

NIH SBIR phase I-II Grant (*Score = 20) $1,715,801

Development of SVAD for HF Therapy(PI: Soucy) 1/1/2013-12/31/2016

(Co-PI: Mark Slaughter) $308,000

AHA National Scientist Development Award

Role of Diminished Pulsatiility

OICN111220(PI: Emma Birks) 3/1/2013- 1/1/2017

(Co-PI: Mark Slaughter) $889,585

REVIVE-IT Trial: Randomized Evaluation of VAD Intervention before Inotropic

Therapy

1R01HL112595-01A1 1/1/2013 – 12/31/2015

(PI: Slaughter & Koenig) $1,926,960

NIH SBIR phase I and II (fastrack) Grant

KSTC-17-OICS-189 1/1/2013-12/31/2015

(PI: Spence, Koenig, Slaughter) $500,000

Kentucky Science and Technology Corporation (KSTC) Grant

Counterpulsation device with integrated EKG sensing

R44 HL103014-01 4/1/2013 –3/31/2015

(PI: Slaughter & Koenig) $3,619,885

NIH SBIR phase II Grant

Development of transapical MVAD for HF therapy

1R44HL117426-01 1/1/2013 –12/31/2015

(PI: Slaughter & Koenig) $2,846,467

NIH SBIR phase I and II (fastrack) Grant

Mark S. Slaughter, M.D. November 15, 2016

26

Apical access system with universal connector for beating heart

LVAD implantation

(PI: Dr. Bolli) 3/1/2012-3/31/2019

(Co-PI: Mark Slaughter) $3,439,793

Regional Clinical Centers for the Cardiovascular Cell Therapy Research Network

CCTRN

2R43HL102981-02A 4/1/2012 – 3/31/2014

(PI: Koenig & Slaughter) $1,616,503

NIH SBIR Phase II Grant

Subcutaneous ECG Sensing

OGMB110749A3 8/1/2012 – 7/31/2013

(Co-PI: Mark Slaughter) $119,782

Wallace H. Coulter Foundation

Left Atrial Appendage Closure Device

Industry Contract 7/1/2012 – 6/30/2014

(PI: Koenig, Slaughter) $70,000

CorMatrix (Atlanta, GA)

MCS Device Testing

Coulter Foundation 2011-Present

(Co-PI: Mark Slaughter) $5,000,000

Coulter Foundation Translational Research Program

Industry Contract

(PI: Slaughter, Koenig) 12/1/2011 – 12/31/2014

HeartWare $750,000

MCS Device Testing

Industry Contract 7/1/2012 – 6/30/2014

(PI: Slaughter, Koenig) $100,000

HeartWare

MCS Device Testing

Industry Contract 4/1/2012 – 4/30/2013

(PI: Slaughter, Giridharan) $39,056

Thoratec

Thoratec pilot hemolysis testing

Industry Contract

(PI: Slaughter, Koenig) 8/1/2011 – 12/31/2012

Thoratec $434,636

MCS Device Testing

Mark S. Slaughter, M.D. November 15, 2016

27

Industry Contract

(PI: Slaughter, Koenig) 8/1/2011 -12/31/2012

Thoratec $192,882

MCS Device Testing

Industry Contract

(PI: Slaughter, Koenig) 8/1/2011 – 12/31/2012

CorMatrix $106,701

ECM Emulsion Testing

Industry Contract 4/1/2010 – 3/31/2013

(PI: Slaughter, Koenig) $100,000

Abiomed

MCS Device Training

Industry Contract 4/1/2010-3/31/2013

(PI: Slaughter) $250,000

HeartWare (Miramar, FL)

MCS Device Training

Industry Contract 4/1/2010 – 3/31/2013

(PI: Slaughter) $250,000

Thoratec (Pleasanton, CA)

MCS Device Training

Industry Contract 4/1/2010 – 3/31/2013

(PI: Slaughter) $100,000

WorldHeart

MCS Device Training

Completed

R43 HL103014-01A1 4/1/2011-9/30/2012

(PI: Slaughter & Koenig) $413,922

NIH SBIR phase I Grant

Industry Contract 2/1/2012 – 6/30/2012

(PI: Slaughter, Giridharan) $115,200

Syncardia

Syncardia hemolysis study

Industry Contract 3/1/2011 – 12/31/2011

(PI: Slaughter, Koenig) $83,841

Mark S. Slaughter, M.D. November 15, 2016

28

Thoratec (Pleasanton, CA)

MCS Device Testing

2R44HL092700-02 (Bosecker) 8/1/2010 –7/31/2012

(co-PIs: Slaughter, Koenig) $1,220,918

NIH-SBIR - Phase II Grant

Intraventricular cardiac assist system for recovery

R43 HL103014-01A1 3/1/2010 –2/28/2011

(PI: Slaughter, Koenig) $413,922

NIH SBIR phase I Grant

Feasibility Testing of Longhorn MVAD

R43HL102981 3/1/2010 –2/28/2011

(PI: Slaughter, Koenig) $244,850

NIH SBIR phase I Grant

Subcutaneous ECG sensing

Industry Contract 8/1/2010 –12/31/2011

(PI: Slaughter, Koenig) $107,411

Abiomed (Danvers, MA)

Symphony Study – GLP Supplement

R43HL102981 3/1/2010 –2/28/2011

(PI: Slaughter & Koenig) $244,850

NIH SBIR phase I Grant

Subcutaneous ECG sensing

Industry Contract 4/1/2010 –12/31/2010

(PI: Slaughter, Koenig) $177,254

Abiomed (Danvers, MA)

Impella 2.5 GLP Study

Industry Contract 8/1/2010 –12/31/2011

(PI: Slaughter, Koenig) $393,116

Abiomed (Danvers, MA)

Symphony Graft Testing Study

Industry Contract 10/1/2009 – 6/30/2012

(PI: Slaughter, Koenig) $206,000

HeartWare (Miami Lakes, FL)

MCS Device Testing

2R44HL088760-02 4/1/2009–3/31/2012

(PI: Slaughter, Koenig) $1,580,486

Mark S. Slaughter, M.D. November 15, 2016

29

NIH-SBIR - Phase II Grant

Portable pneumatic driver for counterpulsation therapy

2R44HL083586-02A1 1/2008–7/31/2011

(PI: Slaughter, Koenig) $1,440,170

NIH-SBIR Phase II Grant

Development of a Counterpulsation Therapy Device

KSTC-184-512-08-054 10/1/2008 –4/30/2010

(PI: Slaughter, Koenig) $500,000

Kentucky Science and Technology Corporation (KSTC) Grant

Implantable Sensing and Triggering System

Industry Contract 9/1/2008 –12/31/2010

(PI: Slaughter) $358,123

HeartWare (Miramar, FL)

MCS Device Chronic Testing Study

Industry Contract 9/1/2008 –12/31/2009

(PI: Slaughter) $148,827

HeartWare (Miramar, FL)

MCS Device Acute Testing Study

1R43HL088760-01 8/1/2007 –7/31/2008

(Slaughter / Consultant) $268,790

NIH-SBIR - Phase I (UofL subcontract)

Portable pneumatic driver for counterpulsation therapy

Industry Contract 4/1/2007 –3/31/2008

(PI: Slaughter) $50,000

Thoratec Corp

Testing flow estimator

1R43HL083586-01 6/1/2006 –1/31/2007

(Slaughter / Consultant) $172,749

NIH-SBIR Phase I (UofL subcontract)

A counterpulsation device to promote myocardial recovery

KSTC-02-DCIS-021 3/1/2007-12/31/2007

(Slaughter/Consultant) $100,000

Kentucky Science and Technology Corp

Counterpulsation device to promote myocardial recovery

Pathophysiologic Benefits 2005

of Continuous and Pulsatile Ventricular Assist $15,000

(Slaughter / PI)

Thoratec Corporation

Mark S. Slaughter, M.D. November 15, 2016

30

Comparison of Epicardial Blood 2003

(PI: Slaughter) $20,000

Flow during LVAD Support

Thoratec Corporation

Comparison of Epicardial Blood 2003

(PI: Slaughter) $10,000

Flow during LVAD Support

Effects of Exercise and Unloading 2001

by LVAD on Myofilament $40,000

Activation in Heart Failure

(Slaughter / Co-Investigator)

Foundation of Physical Therapy

Suppression of the Systemic 2000

Inflammatory Response of $30,000

Cardiopulmonary Bypass

(Slaughter / PI)

Medical Research Fund Christ Hospital

The Use of Leukine to Stimulate 1998-1999

Healing of Leg Wounds after $20,000

Coronary Artery Bypass Graft Surgery,

(Slaughter / Co-Investigator)

Immunex Corporation

Books/Book Chapters:

1. Black MC, Schumer EM, Trivedi JR, Slaughter MS. Recent Advances in Circulatory

Assist Devices. Handbook of Coronary Artery Disease

2. Slaughter MS. A companion to Baunwald’s Heart Disease; Mechanical Circulatory

Support. – Chapter 11: Surgical Methods in Circulatory Support. 2012; pages 141-152.

3. Slaughter MS. Ventricular Assist Devices for Destination Therapy. Atlas of Surgical

Treatment for Advanced Heart Failure. (In Press).

4. Sobieski MA, Giridharan G, Koenig SC, Slaughter MS. Counterpulsation Devices for

Myocardial Support. Cardiothoracic Surgery Review, edited by Franco: 2011 Ch 156,

pages 708-714.

5. Williams ML, Sobieski MA, Giridharan G, Koenig SC, Slaughter MS. Rotary and

Centrifugal Blood Pumps. Cardiothoracic Surgery Review, edited by Franco; 2011, Ch

149: Pages 666-675

Mark S. Slaughter, M.D. November 15, 2016

31

6. Birks E, Slaughter MS. Oxford Textbook of Heart Failure. – Chapter 51: Ventricular

Assist Devices, including Intra-Aortic Balloon Pumps. 51(537-546):2011. New York,

NY, Oxford University.

7. Implants for Surgery – Active implantable medical devices – Part 5: Circulatory Support

Devices. © 2010. Association for the Advancement of Medical Instrumentation.

ANSI/AAMI/ISO 14708-5:2010.

8. Slaughter MS. Cardiac Surgery in Chronic Renal Failure: Patient Management and

Clinical Outcomes. © 2007 Blackwell Publishing Ltd., Oxford, UK.

9. Slaughter MS, Deng M. Mechanical Circulatory Support: Chapter 10. Permanent

Mechanical Circulatory Support. ISHLT Monograph Series 2006.

10. Slaughter MS, Ward HB. Surgical Management of Heart Failure. Clinics in Geriatric

Medicine, Philadelphia, PA. WB Saunders Company, 16(3); 567-92, 2000.

Publications: (H index: 41)

1. Aronson KD, Silvestry SC, Maltais S, Mallidi HR, Frazier OH, Boyce SW, Leadley

K, Najarian KB, Slaughter MS, Pagani FD. Patients Awaiting Heart Transplantation

on HVAD Support for Greater than 2 Years. ASAIO J. 2016 Jul-Aug; 62(4):384-9.

doi: 10.1097/MAT. PMID: 27111739.

2. Cheng A, Schumer EM, Trivedi JR, Van Berkel VH, Massey HT, Slaughter MS.

Does Donor Cardiopulmonary Resusitationi Time Affect Heart Transplantation

Outcomes and Survival? Ann Thorac Surg. 2016 May 10. pii: S0003-4975(16)00218-

6. doi: 10.1016/j.arthoracsur.2016.02.034 [Epub ahead of print] PMID: 27173071

3. Schumer EM, Chaney JH, Trivedi JR, Linsky PL, Williams ML, Slaughter MS.

Emergency Coronary Bypass Grafting: Indications and Outcomes from 2003 through

2013. Tex Heart Inst J. 2016 Jun 1;43(3):214-9. doi: 10.14503/THIJ-14-4978.

eCollection 2016 Jun. PMID: 27303236.

4. Trivedi JR, Rajagopal K, Schumer EM, Birks EJ, Lenneman A, Cheng A, Slaughter

MS. Differences in Status 1A Heart Transplantation Survival in the Continuous Flow

Left Ventricular Assist Device Era. Ann Thorac Surg. 2016 Jun 18. pii: S0003-

4975(16)30354-X. doi: 10. 1016/j.arthoracsur.2016.04.027 [Epub ahead of print]

PMID: 27329191

5. Weerahandi H, Goldstein N, Gelfman LP, Jorde U, Kirpatrick JN, Marble J, Naka Y,

Pinney S, Slaughter MS, Bagiella E, Ascheim DD. Pain and Functional Status in

Mark S. Slaughter, M.D. November 15, 2016

32

Patients with Ventricular Assist Devices. J Pain Symptom Manage. 2016 Jul 8. pii:

S0885-3924(16)30181-6. doi: 10.1016/j.jpainsymman.2016.05016. [Epub ahead of

print] PMID: 27401516

6. Mondal NK, Roychoudhury S, Mukherjee S, Siddique S, Banerjee M, Slaughter MS,

Lahiri T, Ray MR. Increased Risk of Cardiovascular Disease in Premenopausal

Female Ragpickers of Eastern India: Involvement of Inflammation, Oxidative Stress

and Platelet Hyperactivity. Mol Cell Biochem. 2016 Aug;419 (1-2):193-203. doi:

10.1007/s11010-016-2773-3. Epub 2016 Jul 15. PMID:27421852.

7. Cowger JA, Castle L, Aaronson K, Slaughter MS, Moainie S, Walsh M, Salerno C.

ASAIO J. 2016 Mar 7. The HeartMate II Risk Score: An Adjusted Score for

evaluation of all continuous flow left assist devices. PMID:26955002

8. Black MC, Slaughter MS.Proactive or reactive? Best approach to limb ischemia in

peripheral venoarterial extracorporeal life support. J Thorac Cardiovasc Surg. 2015

Dec 13. pii: S0022-5223(15)02395-8. doi: 10.1016/j.jtcvs.2015.11.064.

PMID:26778380

9. Trivedi JR, Cheng A, Ising M, Lenneman A, Birks E, Slaughter MS.

10. ASAIO J. 2016 Jan 13. Heart Transplant Survival Based on Recipient and Donor

Risk Scoring: a UNOS Database Analysis . PMID:26771395

11. Kirklin JK, Naftel DC, Pagani FD, Kormos RL, Myers S, Acker MA, Rogers J,

Slaughter MS, Stevenson LW. Pump Thrombosis in the Thoratec HeartMate II

Device: An Update Analysis of the INTERMACS Registry. J Heart Lung Transplant

2015 Dec; 34(12):1515-26. doi: 10.1016/j.healun.2015.10.024.

12. Chen Z, Mondal NK, Ding J, Koenig, SC, Slaughter MS, Wu ZJ. Paradoxical Effect

of Nonphysiological Shear Stress on Platelets and von Willebrand Factor. Artif

Organs 2015 Nov 18. doi: 10.1111/aor.12606. [Epub ahead of print]

13. Schumer EM, Black MC, Monreal G, Slaughter MS. Left Ventricular Assist

Devices: Current Controversies and Future Directions. Eur Heart J 2015 Nov 4. pii:

ehv590. [Epub ahead of print]

14. Schumer EM, Ising MS, Slaughter MS. The Current State of Left Ventricular Assist

Devices: Challenges Facing Further Development. Expert Rev Cardiovasc Ther 2015

Nov; 13(11):1158-93. doi: 10.1586/14779072.2015. 1098534. Epub 2015 Nov 2.

15. Teuteberg JJ, Slaughter MS, Rogers JG, McGee EC, Pagani FD, Gordon R, Rame E,

Acker M, Kormos RL, Salerno C. Schleeter TP, Goldstein DJ, Shin J, Starling RC,

Wozniak T, Malik AS, Silvestry S, Ewald GA, Jorde UP, Naka Y, Birks E, Najarian

Mark S. Slaughter, M.D. November 15, 2016

33

KB, Hathaway DR, Aaronson KD; ADVANCE Trial Investigators. JACC Heart Fail

2015 Oct;3(10):818-28. doi: 10.1016/j.jchf.2015.05.011.

16. Mondal NK, Sorensen EN, Pham SM, Koenig SC, Griffith BP, Slaughter MS, Wu

ZJ. Systemic Inflammatory Response Syndrome in End-Stage Heart Failure Patients

Following Continuous-Flow Left Ventricular Assist Device Implantation: Differences

in Plasma Redox Status and Leukocyte Activation. Artif Organs 2015 Sept29. doi:

10.1111/aor. 12580 [Epub ahead of print]

17. Ising MS, Sobieski MA, Slaughter MS, Loenig SC, Giridharan GA. Feasibility of

Pump Speed Modulation for Restoring Vascular Pulsatility with Rotary Blood

Pumps. ASAIO J. 2015 Sept-Oct; 61(5):526-32. doi: 10.1097.

18. Bhatia N, Voelkel AJ, Hussain Z, Sharma UC, Slaughter MS, Birks EJ, McCants

KC. Safety and Feasibility of Induction Immunosuppression When Driveline

Infection Is an Indication for Cardiac Transplantation. Thorac Cardiovasc Surg. 2015

Dec; 63(8):675-83. doi: 10.1055/s-0035-1564449. Epub 2015 Sep 14.

19. Schumer EM, Ising MS, Trivedi JR, Slaughter MS, Cheng A. Early Outcomes with

Marginal Donor Hearts Compared with Left Ventricular Assist Device Support in

Patients with Advanced Heart Failure. Ann Thorac Surg. 2015 Aug:100(2):522-7.

doi: 10.1016/j. athoracsur.2015.02.089.Epub 2015 Jun 9.

20. Chen Z, Mondal NK, Ding J, Koenig SC, Slaughter MS, Griffith BP, Wu ZJ.

Activation and Shedding of Platelet Glycoprotein IIB/IIIa Under Non-physiological

Shear Stress. Mol Cell Biochem. 2015 Nov; 409 (1-2): 93-101. doi: 10.1007/211010-

015-2515-y. Epub 2015 Jul 10.

21. Schumer EM, Zoeller KA, Linsky PL, Monreal G, Choi Y, Giridharan GA, Sobieski

MA, Slaughter MS, van Berkel VH. Feasibility Study of Pulsatile Left Ventricular

Assist Device for Prolonged Ex Vivo Lung Perfusion. Ann Thorac Surg. 2015

Jun;99(6):1961-8. doi: 10.1016/j.athoracsur.2015.02.087. Epub 2015 Apr 25.

22. Huang J, Donneyong M, Trivedi J, Barnard A, Chaney J, Dotson A, Raymer S,

Cheng A, Liu H, Slaughter MS. Preoperative Aspirin Use and Its Effect on Adverse

Events in Patients Undergoing Cardiac Operations. Ann Thorac Surg. 2015

Jun;99(6):1975-81. doi: 10.1016/j.athoracsur.2015.02.032. Epub 2015 Apr 23.

23. Birks EJ, McGee EC, Aaronson KD, Boyce S, Cotts WG, Naijar SS, Pagani FD,

Hathaway DR, Najarian K, Jacoski MV, Slaughter MS, ADVANCE Trial

Investigators. An Examination of Survival by Sex and Race in the HeartWare

Ventricular Assist Device for the Treatment of Advanced Heart Failure (ADVANCE)

Bridge to Transplant (BTT) and Continued Access Protocol Trials. J Heart Lung

Transplant 2015 Jun;34(6):815-24. doi: 10.1016/j.healun.2014.12.011. Epub 2014

Mark S. Slaughter, M.D. November 15, 2016

34

Dec 29.

24. Goldstein DJ, Aaronson KD, Tatooles AJ, Silvestry SC, Jeevanandam V, Gordon R,

Hathaway DR, Najarian KB, Slaughter MS, ADVANCE Investigators.

Gastrointestinal bleeding in recipients of the HeartWare Ventricular Assist System.

JACC Heart Fail. 2015 Apr;3(4):303-13. doi: 10.1016/j.jchf.2014.11.008. Epub 2015

Mar 11.

25. Slaughter MS. Chronic implantable mechanical circulatory support 50 years later:

still shooting for the stars! Ann Thorac Surg. 2015 Mar;99(3):749-51. doi:

10.1016/j.athoracsur.2015.01.016.

26. Nielsen VG, Sobieski MA 2nd, Slaughter MS. Left Ventricular Assist Device

Associated Carbon Monoxide and Iron Enhanced Hypercoagulation: Impact of

Concurrent Disease. ASAIO J. 2015 Feb 13. [Epub ahead of print]

27. Rogers JG, Boyle AJ, O'Connell JB, Horstmanshof DA, Haas DC, Slaughter MS,

Park SJ, Farrar DJ, Starling RC. Risk assessment and comparative effectiveness of

left ventricular assist device and medical management in ambulatory heart failure

patients: design and rationale of the ROADMAP clinical trial. Am Heart J 2015 Feb;

169(2): 205-210 e20 doi: 10.1016/j.ahj.2014.11.004. Epub 2014 Nov 11.

28. Giridharan GA, Koenig SC, Soucy KG, Choi Y, Pirbodaghi T, Bartoli CR, Monreal

G, Sobieski MA, Schumer E, Cheng A, Slaughter MS. Left ventricular volume

unloading with axial and centrifugal rotary blood pumps. ASAIO J. 2015 May-

Jun;61(3):292-300. doi: 10.1097.

29. Giridharan GA, Koenig SC, Soucy KG, Choi Y, Pirbodaghi T, Bartoli CR, Monreal

G, Sobieski MA, Schumer E, Cheng A, Slaughter MS. Hemodynamic Changes and

Retrograde Flow in LVAD Failure. ASAIO J. 2015 May-Jun;61(3):282-91. doi:

10.1097.

30. Karkouti K, Grocott HP, Hall R, Jessen ME, Kruger C, Lerner AB, MacAdams C,

Mazer CD, de Medicis É, Myles P, Ralley F, Rheault MR, Rochon A, Slaughter MS,

Sternlicht A, Syed S, Waters T. Interrelationship of preoperative anemia,

intraoperative anemia, and red blood cell transfusion as potentially modifiable risk

factors for acute kidney injury in cardiac surgery: a historical multicentre cohort

study. Can J Anaesth. 2015 Apr;62(4):377-84. doi: 10.1007/s12630-014-0302-y.

Epub 2014 Dec 24.

31. Gopinathannair R, Birks EJ, Trivedi JR, McCants KC, Sutton BS, Deam AG,

Slaughter MS, Hottigoudar RU. Impact of cardiac resynchronization therapy on

Mark S. Slaughter, M.D. November 15, 2016

35

clinical outcomes in patients with continuous-flow left ventricular assist devices. J

Card Fail. 2015 Mar;21(3):226-32. doi: 10.1016/j.cardfail.2014.12.006. Epub 2014

Dec 17.

32. Cheng A, Williamitis CA, Slaughter MS. Comparison of continuous-flow and

pulsatile-flow left ventricular assist devices: is there an advantage to pulsatility? Ann

Cardiothorac Surg. 2014 Nov;3(6):573-81. doi: 10.3978/j.issn.2225-

319X.2014.08.24.

33. Soucy KG, Giridharan GA, Choi Y, Sobieski MA, Monreal G, Cheng A, Schumer E,

Slaughter MS, Koenig SC. Rotary pump speed modulation for generating pulsatile

flow and phasic left ventricular volume unloading in a bovine model of chronic

ischemic heart failure. J Heart Lung Transplant. 2015 Jan;34(1):122-31. doi:

10.1016/j.healun.2014.09.017. Epub 2014 Sep

34. Soucy KG, Smith EF, Monreal G, Rokosh G, Keller BB, Yuan F, Matheny RG,

Fallon AM, Lewis BC, Sherwood LC, Sobieski MA, Giridharan GA, Koenig SC,

Slaughter MS. Feasibility study of particulate extracellular matrix (P-ECM) and left

ventricular assist device (HVAD) therapy in chronic ischemic heart failure bovine

model. ASAIO J. 2015 Mar-Apr;61(2):161-9. doi: 10.1097.

35. Schumer E, Monreal G, Carnahan S, et al. Outcomes for heart transplantation in

patients older than 64. J Ky Med Association.* Oct 2014; 112(10): 221-225.

36. Wang Y, Koenig S, Slaughter M, Giridharan G. Suction prevention and physiologic

control of continuouse flow left ventricular assist devices using intrinsic pump

parameters. ASAIO J. 2014 Nov 13.

PMID 25396276.

37. Abraham WE, Aggarwal S, Prabhu SD, Cecere R, Pamboukian SV, Bank AJ, Sun B,

Pae WE Jr, Hayward CS, McCarthy PM, Peters WS, Verta P, Slaughter MS; C-Pulse

Trial Study Groupd. Ambulatory extra-aortic Counterpulsation in patients with

moderate to severe chronic heart failure. JACC Heart Fail. 2014 Oct;2(5):526-33.

Doi: 10.1016/j.jchf.2014.04.014

PMID 25301151.

38. Wang Y, Koenig S, Slaughter M, Giridharan G. Rotary blood pump control strategy

for preventing left ventricular suction. ASAIO J. 2014 Sept. 22

PMID: 25248043

39. Koenig SC, Jimenez JH, West SD, Sobieski MA, Choi Y, Monreal G, Giridharah GA,

Soucy KG, Slaughter MS. Early feasibility testing and engineering development of a

sutureless beating heart connector for left ventricular assist devices. ASAIO J. 2014

Nove-Dec;60(6):317-25. doi: 10.1097.

Mark S. Slaughter, M.D. November 15, 2016

36

PMID: 25238500.

40. Wieselthaler GM, Slaughter M. Artif Organs Welcome to ISRBP 2014. 2014

Sep;38(9): 725-6. Doi: 10.1111/aor.12405. No abstract available.

PMID 25234755.

41. Slaughter MS, Soucy KG, Matheny RG, Lewis BC, Hennick MF, Choi Y, Monreal

G, Sobieski MA, Giridharan GA, Koenig SC. Development of an extracellular matrix

delivery system for effective intramyocardial injection in ischemic tissue. ASAIO J.

2014 Nov-Dec;60(6):730-6. Doi: 10.1097.

PMID 25232775.

42. Cheng A, Monreal G, William ML, Sobieski M 2nd, Slaughter MS. Extended extra-

aortic Counterpulsation with the C-pulse device does not alter aortic wall structure.

ASAIO J. 2014 Nov-Dec;60(6):e5-7. Doi: 10.1097.

PMID: 25158886.

43. Cheng A, Slaughter MS. J Thorac Dis. 2014 Aug; 6(8):1105-9. Doi:

10.3978/j.issn.2072-1439.2014.07.37. Heart Transplantation.

PMID: 25132977. *KMA Journal not listed in Pubmed

44. Trivedi JR, Cheng A, Singh R, Williams ML, Slaughter MS; Survival on the heart

transplant waiting list; impact of continuous flow left ventricular assist device as

bridge to implant. Ann Thorac Surg. 2014 Sept;98(3):830-4. Doi:

10.1016/j.athoracsur.2014.05.019. Epub 2014 july 31.

PMID 25087934

45. John R, Aaronson KD, Pae WE, Ackere MA, Hathaway DR, Najarian KB, Slaughter

MS; HeartWare Bridge to Transplant ADVANCE Trial Investigators. Drive Line

Infections and sepsis in patients receiving the HVAD system as a left ventricular

assist device. J Heart Lung Transplant. 2014 Oct; 33(10): 1066-73. Doi:

10.4016/j.healun.2014.05.010. Epub 2014 Jun 4.

PMID: 25087103.

46. Linsky PL, Choi Y, Ouseph R, Slaughter MS, Keller BB, Jones CM. High

Resolution Imaging using the VisualSonics Vevo 2100 on Isolated, Perfused Procine

Kidneys on mechanical Circulatory Support

ASAIO J. 2014 May 8 (Epub ahead of print)

PMID: 24814832.

47. Linsky PL, Slaughter MS. Bud Frazier’s 1000th Implantation of a Ventricular Assist

Device. Tex Heart Inst J. 2014 Apr 1;41(2):110-1. doi: 10.14503/THIJ-14-4113.

Mark S. Slaughter, M.D. November 15, 2016

37

eCollection 2014. PMID: 24808765.

48. Brisco MA, Sundareswaran KS, Milano CA, Feldman D, Testani JM, Ewald GA,

Slaughter MS, Farrar DJ, Goldberg LR. The Incidence, Risk, and Consequences of

Atrial Arrhythmias in Patients with Continuous-Flow Left Ventricular Assist Devices.

J Card Surg. 2014 Apr 18.

49. Donneyong M, Cheng A, Trivedi JR, Schumer E, McCants KC, Birks EJ, Slaughter

MS. The Association of Pre-Transplant HeartMate II Left Ventricular Assist Device

Placement and Heart Transplantation Mortality. ASAIO J. 2014 Mar 7.

50. Jorde UP, Kushwaha SS, Tatooles AJ, Naka Y, Bhat G, Long JW, Horstmanshof DA,

Kormos RL, Teuteberg JJ, Slaughter MS, Birks EJ, Farrar DJ, Park SJ; HeartmATE

ii Clinical Investigators. “Results of the Destination Therapy Post-FDA-Approval

Study with a Continuous Flow Left Ventricular Assist Device: A Prospective Study

Using the INTERMACS Registry.J Am Coll Cardiol. 2014 Feb 21.

51. Giridharan GA, Koenig SC, Slaughter MS. “Do Axial –Flow LVADs Unload Better

than Centrifugal-Flow LVADs? ASAIO J. 2014 Mar-Apr.

52. Shah KB, Kwakkel-van Erp JM, Migliore C, Orr Y, Corris PA, Glanville AR,

Slaughter MS, West

LJ, Mehra MR. “Scientific progress in heart and lung failure, mechanical circulatory

support, and transplantation: Highlights from the Journal of Heart and Lung

Transplantation.” J Heart Lung Transplant. 2013 Dec 4.

53. Slaughter MS. “O.H. “Bud” Frazier, M.D. Mechanical Circulatory Support Pioneer”.

Texas Heart Institute Journal. Jan 29, 2014.

54. Najjar SS, Slaughter, MS, Pagani FD, Starling RC, McGee EC, Eckman P, Tatooles

AJ, Moazami N, Kormos RL, Hathaway DR, Najarian KB, Bhat G, Aaronson KD,

Boyce SW. HVAD Bridge to Transplant ADVANCE Trial Investigators. “An

analysis of pump thrombus events in patients in the HeartWare ADVANCE bridge to

transplant and continued access protocol trial”. J Heart Lung Transplant. 2014 Jan.

55. Tamez D, Larose JA, Shambaugh C, Chorpenning K, Soucy KG, Sobieski MA,

Sherwood L, Giridharan GA, Monreal G, Koenig SC, Slaughter MS. “Early

Feasibility Testing and Engineering Development of the Transapical Approach for the

HeartWare MVAD Ventricular Assist System.” ASAIO J. 2014 Jan 22.

56. Slaughter MS. “Shaping the Future!” ASAIO J. 2014 Jan-Feb.

57. Monreal G, Sherwood LC, Sobieski MA, Giridharan GA, Slaughter MS, Koenig SC.

“Large Animal Models for Left Ventricular Assist Device Research and

Development”. ASAIO J. 2014 Jan-Feb.

Mark S. Slaughter, M.D. November 15, 2016

38

58. Slaughter MS. Long-Term Mechanical Circulatory Support for Advanced Heart

Failure: “The Tide is Turning”. Eur J Heart Fail. 2013 Oct.

59. Williams ML, He X, Rankin JS, Slaughter MS, Gammie JS. Preoperative Hematocrit

is a Powerful Predictor of Adverse Outcomes in Coronary Artery Bypass Graft

Surgery: A Report From The Society of Thoracic Surgeons Adult Cardiac Surgery

Database. Ann Thorac Surg. 2013 Sep 19.

60. Cheng A, Slaughter MS. How I Choose Conduits and Configure Grafts for my

Patients-Rationales and Practices. Ann Cardiothoracic Surg. 2013 Jul.

61. Pagni S, Ganzel BL, Trivedi JR, Singh R, Mascio CE, Austin EH, Slaughter MS,

Williams ML. Early and Midterm Outcomes Following Surgery for Acute Type A

Aortic Dissection. J Card Surg. 2013 Aug 2.

62. Bartoli CR, Sherwood LC, Giridharan GA, Slaughter MS, Wead WB, Prabhu SD,

Koenig SC. Bovine Model of Chronic Ischemic Cardiomyopathy: Implications for

Ventricular Assist Device Research. Artif Organs. 2013 Jul 22.

63. Hottigoudar RU, Deam AG, Birks EJ, McCants KC, Slaughter MS, Gopinathannair

R. Catheter ablation of atrial flutter in patients with left ventricular assist device

improves symptoms of right heart failure. Congest Heart Fail. 2013 Jul.

64. Soucy KG, Koenig SC, Sobieski MA, Slaughter MS, Giridharan GA. Fault detection

in rotary blood pumps using motor speed response. ASAIO J. 2013 Jul-Aug.

65. Trivedi JR, Sobieski MA, Schwartz S, Williams ML, Slaughter MS. Novel

thrombosis risk index as predictor of left ventricular assist device thrombosis. ASAIO

J. 2013 Jul-Aug.

66. Soucy KG, Koenig SC, Giridharan GA, Sobieski MA, Slaughter MS. Rotary pumps

and diminished pulsatility: do we need a pulse? ASAIO J. 2013 Jul-Aug.

67. Slaughter MS, Pagani FD, McGee EC, Birks EJ, Cotts WG, Gregoric I, Howard

Frazier O, Icenogle T, Najjar SS, Boyce SW, Acker MA, John R, Hathaway DR,

Najarian KB, Aaronson KD; HeartWare Bridge to Transplant ADVANCE Trial

Investigators. HeartWare ventricular assist system for bridge to transplant: Combined

results of the bridge to transplant and continued access protocol trial. J Heart Lung

Transplant. 2013 Jul.

68. Ising M, Koenig S, Sobieski M, Slaughter M, Giridharan G. “Flow Modulation

Algorithms for Intra-Aortic Rotary Blood Pumps to Reduce Coronary Steal.” 2011

Biomedical Engineering Society Annual Meeting, Hartford, CT, October 12 – 15,

2011.

Mark S. Slaughter, M.D. November 15, 2016

39

69. Sherwood LC, Sobieski MA, Koenig SC, Giridharan GA, Slaughter MS. Benefits of

aggressive medical management in a bovine model of chronic ischemic heart failure.

ASAIO J. 2013 May-Jun.

70. Rumsfeld JS, Alexander KP, Goff DC Jr, Graham MM, Ho PM, Masoudi FA, Moser

DK, Roger VL, Slaughter MS, Smolderen KG, Spertus JA, Sullivan MD, Treat-

Jacobson D, Zerwic JJ; American Heart Association Council on Quality of Care and

Outcomes Research, Council on Cardiovascular and Stroke Nursing, Council on

Epidemiology and Prevention, Council on Peripheral Vascular Disease, and Stroke

Council. Cardiovascular health: the importance of measuring patient-reported health

status: a scientific statement from the American Heart Association. Circulation. 2013

Jun 4.

71. Dassanayaka S, Slaughter MS, Bartoli CR. Mechanistic pathway(s) of acquired von

willebrand syndrome with a continuous-flow ventricular assist device: in vitro

findings. ASAIO J. 2013 Mar-Apr.

72. Soucy KG, Koenig SC, Giridharan GA, Sobiesku, MA, Slaughter MS. Defining

pulsatility during continuous-flow ventricular assist device support. J Heart Lung

Transplant. 2013 Mar 26.

73. Bartoli CR, McCants KC, Birks EJ, Flaherty MP, Slaughter MS. Percutaneous

closure of a patent foramen ovale to prevent paradoxical thromboembolism in a

patient with a continuous-flow LVAD. J Invasive Cardiol. 2013 Mar.

74. Gordon RJ, Weinberg AD, Pagani FD, Slaughter MS, Pappas PS, Naka Y, Goldstein

DJ, Dembitsky WP, Giacalone JC, Ferrante J, Ascheim DD, Moskowitz AJ, Rose

EA, Gelijns AC, Lowy FD. Prospective, multicenter study of ventricular assist device

infections. Circulation. 2013 Feb 12.

75. Cowger J, Sundareswaran K, Rogers JG, Park SJ, Pagani FD, Bhat G, Jaski B, Farrar

DJ, Slaughter MS. Predicting Survival in Patients Receiving Continuous Flow Left

Ventricular Assist Devices: The HeartMate II Risk Score. J Am Coll Cardiol. 2013

Jan 22.

76. Moazami N, Milano CA, John R, Sun B, Adamson RM, Pagani FD, Smedira N,

Slaughter MS, Farrar DJ, Frazier OH; HeartMate II Investigators. Pump replacement

for left ventricular assist device failure can be done safely and is associated with low

mortality. Ann Thorac Surg. 2013 Feb.

77. Huang J, Slaughter MS. HeartWare ventricular assist device placement in a patient

with congenitally corrected transposition of the great arteries. J Thorac Cardiovasc

Surg. 2013 Feb.

78. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS,

Mark S. Slaughter, M.D. November 15, 2016

40

Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J,

Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P,

Higgins R, Mack M. Statement regarding the pre and post market assessment of

durable, implantable ventricular assist devices in the United States. J Heart Lung

Transplant. 2012 Dec.

79. Emani S, Brewer RJ, John R, Slaughter MS, Lanfear DE, Ravi Y, Sundareswaran

KS, Farrar DJ, Sai-Sudhakar CB. Patients with low compared with high body mass

index gain more weight after implantation of a continuous-flow left ventricular assist

device. J Heart Lung Transplant. 2013 Jan.

80. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS,

Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J,

Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P,

Higgins R, Mack M. Statement regarding the pre and post market assessment of

durable, implantable ventricular assist devices in the United States. Ann Thorac Surg.

2012 Dec.

81. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS,

Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J,

Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P,

Higgins R, Mack M. Statement regarding the pre and post market assessment of

durable, implantable ventricular assist devices in the United States: Executive

Summary. Ann Thorac Surg. 2012 Dec.

82. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS,

Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J,

Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P,

Higgins R, Mack M. Statement regarding the pre and post market assessment of

durable, implantable ventricular assist devices in the United States. Circ Heart Fail.

2013 Jan 1.

83. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS,

Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J,

Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P,

Higgins R, Mack M. Statement regarding the pre and post market assessment of

durable, implantable ventricular assist devices in the United States: Executive

Summary. Circ Heart Fail. 2013 Jan 1.

84. Slaughter MS, Singh R. The Role of Ventricular Assist Devices in Advanced Heart

Failure. Rev Esp Cardiol. 2012 Nov.

85. Chugh AR, Beache GM, Loughran JH, Mewton N, Elmore JB, Kajstura J, Pappas P,

Tatooles A, Stoddard MF, Lima JA, Slaughter MS, Anversa P, Bolli R.

Mark S. Slaughter, M.D. November 15, 2016

41

Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the

SCIPIO trial: surgical aspects and interim analysis of myocardial function and

viability by magnetic resonance. Circulation. 2012 Sep 11.

86. Giridharan GA, Lee TJ, Ising M, Sobieski MA, Koenig SC, Gray LA, Slaughter MS.

Miniaturization of mechanical circulatory support systems. Artif Organs. 2012 Aug.

87. Sobieski MA, Giridharan GA, Ising M, Koenig SC, Slaughter MS. Blood Trauma

Testing of CentriMag and RotaFlow Centrifugal Flow Devices: A Pilot Study. Artif

Organs. 2012 Aug.

88. Slaughter MS. Summary of the 19th congress of the international society for rotary

blood pumps. Artif Organs. 2012 Aug.

89. Sayfo S, Stepp LO, Ganzel B, Slaughter MS, Flaherty MP. Management of

Recurrent Leaks Following Postinfarction Ventricular Septal Defect Repairs. J Card

Surg. 2012 Aug 13.

90. Giridharan GA, Cheng RC, Glower JS, Ewert DL, Sobieski MA, Slaughter MS,

Koenig SC. Control strategies for afterload reduction with an artificial vasculature

device. ASAIO J. 2012 Jul.

91. Slater AD, Tatooles AJ, Coffey A, Pappas PS, Bresticker M, Greason K, Slaughter

MS. Prospective clinical study of a novel left atrial appendage occlusion device. Ann

Thorac Surg. 2012 Jun.

92. Aaronson KD, Slaughter MS, Miller LW, McGee EC, Cotts WG, Acker MA, Jessup

ML,

Gregoric ID, Loyalka P, Frazier OH, Jeevanandam V, Anderson AS, Kormos RL,

Teuteberg JJ, Levy WC, Naftel DC, Bittman RM, Pagani FD, Hathaway DR, Boyce

SW; for the HeartWare Ventricular Assist Device (HVAD) Bridge to Transplant

ADVANCE Trial Investigators. Use of an Intrapericardial, Continuous-Flow,

Centrifugal Pump in Patients Awaiting Heart Transplantation. Circulation. 2012 Jun

26.

93. Gordon RJ, Miragaia M, Weinberg AD, Lee CJ, Rolo J, Giacalone JC, Slaughter

MS, Pappas P, Naka Y, Tector AJ, de Lencastre H, Lowy FD. Staphylococcus

epidermidis colonization is highly clonal across US cardiac centers. J Infect Dis. 2012

May 1.

94. Slaughter MS, Rogers JG. Editorial Commentary: Determining the cost-

effectiveness of mechanical circulatory support. J Heart Lung Transplant 2012 May.

95. Cannon RM, Trivedi JR, Pagni S, Dwivedi A, Bland JN, Slaughter MS, Ross CB,

Richardson JD, Williams ML. Open repair of blunt thoracic aortic injury remains

relevant in the endovascular era. J Am Coll Surg. 2012 Jun.

Mark S. Slaughter, M.D. November 15, 2016

42

96. Williams ML, Ganzel BL, Slater AD, Slaughter MS, Trivedi JR, Edmonds HL,

Pagni S, Antegrade Versus Retrograde Cerebral Protection in Repair of Acute

Ascending Aortic Dissection. Amer Surg. 2012 Mar.

97. Slaughter MS. Invited Commentary. Ann of Thor Surg. 2012 Mar.

98. Park SJ, Milano CA, Tatooles AJ, Rogers JG, Adamson RM, Steidley DE, Ewald

GA, Sundareswaran KS, Farrar DJ, Slaughter MS. Outcomes in advanced heart

failure patients with left ventricular assist devices for destination therapy. Circulation

Heart Fail. 2012 Mar 1.

99. Petrucci RJ, Rogers JG, Blue L, Gallagher C, Russell SD, Dordunno D, Jaski BE,

Chillcott S, Sun B, Yanssen TL, Tatooles A, Koundakjian L, Farrar DJ, Slaughter

MS. Neurocognitive function in destination therapy patients receiving continuous-

flow vs pulsatile-flow left ventricular assist device support. J Heart Lung Transplant.

2012 Jan.

100. *Rogers JG, Bostic RR, Tong KB, Adamson R, Russo M, Slaughter MS. Cost-

effectiveness analysis of continuous-flow left ventricular assist devices as destination

therapy. Circ Heart Fail. 2012 Jan.

*Circulation: Heart Failure Editors' Picks: Most Important Articles Published in

2012

101. Slaughter, MS. Implantation of the HeartWare Left Ventricular Assist Device.

Semin Thoracic Cardiovasc Surg. 2011 Autumn.

102. Slaughter MS. Invited Commentary. Ann Thorac Surg. 2011 Dec.

103. Giridharan GA, Lederer C, Berthe A, Goubergrits L, Hutzenlaub J, Slaughter MS,

Dowling RD, Spence PA, Koenig SC. Flow dyanmics of a novel counterpulsation

device characterized by CFD and PIV modeling. Medical Engineering & Physics

(Epub ahead of print June 2011) 2011 Dec.

104. Slaughter MS. UNOS Status of Heart Transplant Patients Supported with a Left

Ventricular Assist Device: Is It Time to Reconsider the Status Criteria? Tex Heart

Inst J. 2011.

105. Hottigoudar RU, Deam AG, Slaughter MS, Sutton BS, McCants K, Birks E,

Gopinathannair R. Ventricular Tachycardia Ablation in Patients with HeartMate II Left

Ventricular Assist Devices: Rhythm Still Matters in Bionic Age. J of Innov Cardiac

Rhythm Mgmt. 2011 November.

Mark S. Slaughter, M.D. November 15, 2016

43

106. Bolli R, Chugh AR, D’Amario D, Loughran JH, Stoddard MF, Ikram S, Beache GM,

Wagner SG, Leri A, Hosoda T, Sanada F, Elmore JB, Goichberg P, Cappetta D,

Solankhi NK, Fahsah I, Rokosh DG, Slaughter MS, Kajstura J, Anversa P. Cardiac

Stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a

randomized phase 1 trial. Lancet. 2011 Nov 26.

107. Joshi JK, Beache GM, Slaughter MS, Sobieski MA, Schneider W, Stoddard MF.

Coronary artery fistula: 64-Slice Computed Tomographic delineation and correlation

with Multiplane Trasnesophageal Echocardiography and Surgical findings.

Echocardiography. 2011 Nov 13.

108. Slater AD, Tatooles A, Coffee A, Pappas P, Bresticker M, Pagni S, Beckman D,

Wozniak T, Greason K, Ganzel B, Rousu A, Austgen C, Stoddard M, Slaughter MS.

Prospective Clinical Study of TigerPaw® Left Atrial Appendage Occlusion Device.

Ann Thorac Surg. 2012 Jun.

109. Meyer A, Slaughter M. The total artificial heart. Panminera Med. 2011 Sep.

110. Giridharan GA, Sobieski MA, Ising M, Slaughter MS, Koenig SC. Blood trauma

testing for mechanical circulatory support devices. Biomed Instrum Technol. 2011

Jul-Aug.

111. Chug AR, Loughran JH, Slaughter MS. Circadian variations in blood pressure in

health and disease: implications for patient management. Journal of

Chronophysiology and Therapy. 2011 Aug.

112. Slaughter MS. Implantation of the HeartWare Left Ventricular Assist Device.

Semin Thorac Cardiovasc Surg. 2011 Autumn.

113. Slaughter MS. Risk Assessment for Continuous Flow Left Ventricular Assist

Devices (LVAD): Does the Destination therapy Risk Score Work? An Analysis of

Over 600 Patients. J Am Coll Cardiol 2011.

114. Slaughter MS, Meyer AL, Birks EJ. Destination therapy with Left Ventricular

Assist Devices: Patient Selection and Outcomes. Current Opinion in Cardiology.

Curr Opin Cardiol 2011 May.

115. Meyer AL, Williams ML, Slaughter, MS. The percutaneous ventricular assist device

TandemHeart in severe efractory cardiogenic shock. Interv. Cardiol. (2011).

116. Slaughter MS, Bostic R, Tong K, Russo M, Rogers J. Temporal Changes in

Hospital Costs for Left Ventricular Assist Device Implantation. J Card Surg. 2011

Sep.

117. Williams ML, Trivedi JR, McCants KC, Prabhu SD, Birks EJ, Oliver L, Slaughter

MS. Heart Transplant Vs. Left Ventricular Assist Device (LVAD) In Heart

Mark S. Slaughter, M.D. November 15, 2016

44

Transplant Eligible Patients. Ann Thorac Surg. 2011 May.

118. Williams ML, Trivedi JR, Doughtie CA, Slaughter MS. Is Female Sex an

Independent Risk Factor for Perioperative Transfusion in Coronary Artery Bypass

Graft Surgery? J Am Coll Surg. 2011 Mar.

119. Hall JL, Fermin DR, Birks EJ, Barton PJ, Slaughter M, Eckman P, Baba HA,

Wohschlaeger J, Miller LW. Clinical, molecular and genomic changes in response to

a left ventricular assist device. J Am Coll Cardiol.2011 Feb 8.

120. Slaughter MS, Pederson B, Graham JD, Sobieski MA, Koenig SC. Evaluation of

new Forcefield Technology: Reducing platelet adhesion and cell coverage of

pyrolytic carbon surfaces. J thorac Cardiovasc Surg. 2011 Oct.

121. Slaughter MS, Giridharan GA, Tamez D, Larose J, Sobieski MA, Sherwood L,

Koenig SC. Transapical miniaturized ventricular assist device: Design and initial

testing. J Thorac Cardiovasc Surg. 2011 Sep.

122. Huang J, Slaughter, MS. Congenital Partial Absence of the Pericardium. The Annals

of Thoracic Surgery. Ann Thorac Surg. 2011 Feb. Cowger JA, Castle L, Aaronson

K, Slaughter MS, Moainie S, Walsh M, Salerno C.

123. Slaughter MS. Arterial conduits for surgical revascularization. Circulation. 2011

Sep 20.

124. Slaughter MS. Excellent outcomes with use of synthetic vascular grafts for

treatment of mycotic pseudoneurysms after heart transplantation. Ann Thorac Surg.

Invited Commentary accepted August 2011.

125. Huang J, Slaughter MS. Continuous aortic Regurgitation with Ventricular Assist

Device. Anesthesiology 2011 Aug.

126. Slaughter MS, Sobieski MA, Graham JD, Pappas PS, Tatooles AJ, Koenig SC.

Platelet Activation in Heart Failure Patients Supported by the HeartMate II

Ventricular Assist Device. Int J Artif Organs. 2011 Jun.

127. Tueteberg J, Rogers JG, Park SJ, Ewald GA, Tatooles AJ, Lietz K, Miller LW,

Kormos RL, Sundareswaran KS, Farrar DJ, Sla

128. Slaughter MS. Will destination therapy be limited to large transplant centers? Tex

Heart Inst J. 2010.

129. Slaughter MS. Hematologic Effects of Continuous Flow Left Ventricular Assist

Mark S. Slaughter, M.D. November 15, 2016

45

Devices. J of Cardiovasc Trans Res. 2010 Dec.

130. Meyer AL, Malesha D, Bara C, Budde U, Slaughter MS, Haverich A, Strueber M.

Acquired von Willebrand Syndrome in Patients with an Axial Flow Left Ventricular

Assist Device. Circ Heart Fail. 2010 Nov 1.

131. Slaughter MS. The Ideal Conduit for Surgical Revascularization. The Quest for the

Holy Grail Continues. Circulation 2010Aug 31.

132. Slaughter MS. Introduction to LVAD Papers. J Card Surg 2010 Jul.

133. Slaughter MS, Myers TJ. Transcutaneous Energy Transmission for Mechanical

Circulatory Support Systems: History, Current Status, and Future Projects. J Card

Surg 2010 Jul.

134. Slaughter, MS. Long-Term Continuous Flow Left Ventricular Assist Device Support

and Eng-Organ Function: Prospects for Destination Therapy. J Card Surg 2010 Jul.

135. Bartoli CR, Giridharan GA, Litwak KN, Sobieski M, Prabhu SD, Slaughter MS,

Koenig SC. Hemodynamic Responses to Continuous versus Pulsatile Mechanical

Unloading of the Failing Left Ventricle. ASAIO J. 2010 Sep-Oct.

136. Bartoli CR, Wilson GC, Giridharan GA, Slaughter MS, Sherwood LC, Spence PA,

Prabhu SD, Koenig SC. A Novel Subcutaneous Counterpulsation Device: Acute

Hemodynamic Efficacy During Pharmacologically Induced Hypertension,

Hypotension, and Heart Failure. Artifical Organs. 2010 Jul.

137. Guan Y, Karkhanis T, Wang S, Rider A, Koenig SC, Slaughter MS, El Banayosy A,

Undar A. Physiologic benefits of pulsatile perfusion during mechanical circulatory

support for the treatment of acute and chronic heart failure in adults. Artif Organs.

2010 Jul.

138. Rogers JG, Aaronson KD, Boyle AJ, Russell SD, Milano CA, Pagani FD, Edwards

BS, Park S, John R, Conte JV, Farrar DJ, Slaughter MS; HeartMate II Investigators.

Continuous flow left ventricular assist device improves functional capacity and

quality of life of advanced heart failure patients. J Am Coll Cardiol. 2010 April 27.

139. Slaughter MS, Naka Y, John R, Boyle A, Conte JV, Russell SD, Aaronson KD,

Sundareswaran KS, Farrar DJ, Pagani FD. Post-operative heparin may not be required

for transitioning patients with a HeartMatt II left ventricular assist system to long-

term warfarin therapy. J Heart Lung Transplant. 2010.

140. Maury, P, Delmas C, Trouillet C, Slaughter MS, Lairez O, Galinier M, Roncalli J,

Bertrand D, Mathevet L, Duparc A, Salvador M, Delay M, Dambrin C. First

experience of percutaneous radio-frequency ablation for atrial flutter and atrial

fibrillation in a patient with HeartMate II left ventricular assist device. J Interv Card

Mark S. Slaughter, M.D. November 15, 2016

46

Electrophysiol.

141. Slaughter MS, Ising MS, Tamez D, O’Driscoll G, Voskoboynikov N, Bartoli CR,

Koenig SC, Giridharan GA. Increase in circadian variation after continuous-flow

ventricular assist device implantation. J Heart Lung Transplant. 2010 Jun.

142. Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD, Starling RC,

Chen L, Boyle AJ, Chillcott S, Adamson RM, Blood MS, Camacho MT, Idrissi KA,

Petty M, Sobieski M, Wright S, Myers TJ, Farrar DJ; HeartMate II Clinical

Investigators. Clinical Management of continous-flow left ventricular assist devices

in advanced heart failure. J Heart Lung Transplant. 2010 Apr.

143. Coyle LA, Ising MS, Gallagher C, Bhat G, Kurien S, Sobieski MA, Slaughter MS.

Destination Therapy: One Year Outcomes in Patients with a Body Mass Index

Greater Than 30. Artif Organs. 2010 Feb.

144. Slaughter, MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, et al.

Advanced Heart Failure Treated with Continuous-Flow Left Ventricular Assist

Device. N Engl J Med 2009.

145. Lietz K, Long JW, Kfoury AG, Slaughter MS, Silver MA, Milano CA, Rogers JG,

Miller LW, Deng M, Naka Y, Mancini, D. Impact of center volume on outcomes of

left ventricular assist device implantation as destination therapy: analysis of the

Thoratec HeartMate Registry, 1998 to 2005. Circ Heart Fail. 2009 Jan.

146. Boyle, AJ, Russell SD, Teuteberg JJ, Slaughter MS, Moazami N, Pagani FD, Frazier

OH, Heatley G, Farrar DJ, John R. Low thromboembolism and pump thrombosis with

the HeartMatt II left ventricular assist device: analysis of outpatient anti-coagulation.

J Heart Lung Transplant. 2009 Sep.

147. Slaughter MS, Sobieski MA, Tamez D, Horrell T, Graham J, Pappas PS,Tatooles

AJ, LaRose J. HeartWare miniature axial-flow ventricular assist device: design and

initial feasibility test Tex Heart Inst J. 2009.

148. Slaughter MS. Outcomes of Medicare Beneficiaries With Ventricular Assist

Devices. JAMA. 2009.

149. Slaughter MS, Bartoli CR, Sobieski MA, Pantalos GM, Giridharan GA, Dowling

RD, et al. Intraoperative evaluation of the HeartMate II flow estimator J Heart Lung

Transplant. 2009 Jan.

150. Koenig SC, Giridharan GA, Ewart DL, Schoeder MJ, Ionan C, Slaughter MS, et al

Human, bovine and porcine systematic vascular input impedances are not equivalent

Mark S. Slaughter, M.D. November 15, 2016

47

implications for device testing and xenotransplantation in heart failure. J Heart Lung

Transplant. 2008 Dec.

151. Koenig SC, Litwak KN, Giridharan GA, Pantalos GM, Dowling RD, Prabhu SD,

Slaughter MS, et al Acute hemodynamic efficacy of a 32-ml subcutaneous

counterpulsation device in a calf model of diminished cardiac function. ASAIO J.

2008 Nov-Dec.

152. Pisano C, Nutter A, Ziebarth C, Cooke G, Slaughter M, Silver MA. Can we detect

fatal heart failure? J Cardiac Failure 2008.

153. Lietz K, Long J, Kfour A, Slaughter M, Silver M, Milano C, et al. The Impact of

Center Volume on Outcomes of Left-Ventricular Assist Device Implantation as

Destination Therapy – Analysis of Thoratec Heartmate Registry 1998-2005

Circulation (2008).

154. Slaughter MS, Sobieski MA, Tatooles AJ, Pappas PS. Reducing Emboli in Cardiac

Surgery: Does it Make a Difference? Artif Organs. 2008 Nov.

155. Aggarwal S, Slaughter MS. Acute myocardial infarction complicated by cardiogenic

shock: role of mechanical circulatory support Expert Rev Cardiovasc Ther. 2008 Oct.

156. Slaughter MS, Sobieski MA, Gallagher C, Dia M, Silver MA Low incidence of

neurologic events during long-term support with the HeartMate XVE left ventricular

assist device Tex Heart Inst J 2008.

157. Slaughter MS, Sobieski MA II, Tamez D, Horrell T, Graham J, Pappas PS, Tatooles

AT, LaRose J Design Concepts and Initial Tests of a New Miniature Ventricular

Assist Device: The HeartWare MVAD™. Texas Heart Institute Journal September

2008.

158. Sobieski MA, Graham JD, Pappas PS, Tatooles AJ, Slaughter MS Reducing the

Effects of the Systemic Inflammatory Response to Cardiopulmonary Bypass: Can

Single Dose Steroids Blunt SIRS? ASAIO J. 2008 Mar-Apr.

159. Coye LA, Martin MM, Kurien S, Graham JD, Gallagher C, Silver MA, Slaughter

MS. Destination Therapy: Safety and Feasibility of National and International

Mark S. Slaughter, M.D. November 15, 2016

48

Travel. ASAIO J. 2008 Mar-Apr.

160. Slaughter MS, Sobieski MA, Gallagher C, Graham J, Brindise J, Stein R Fibrinolytic

Activation During Long-term Support With the HeartMate II Left Ventricular Assist

Device. ASAIO J. 2008 Jan-Feb.

161. Feldman CM, Khan SN, Slaughter MS, Sobieski M, Graham JD, Eaheart B, Silver

MA. Improvement in early oxygen uptake kinetics with left ventricular assist device

support. ASAIO J. 2008 Jul-Aug.

162. Koenig SC, Giridharan GA, Ionan C, Pantalos GM, Dowling RD, Prabhu S, Sobieski

MA, Slaughter MS. Systemic vascular input impedance in humans, calves and pigs:

Clinical implication with medical devices and xenotransplantation. J Heart and Lung

Transp 2007.

163. Slaughter MS, Jweied E. Managing mechanical valves with reduced anticoagulation.

Expert Rev Cardiovasc Ther. 2007 Nov.

164. Leitz K, Long JW, Kfoury AG, Slaughter MS, Silver MA, Milano CA, Rogers JG,

Naka Y, Mancini D, Miller LW. Outcomes of Left Ventricular Assist Device

Implantation as Destination Therapy in the Post-REMATCH Era. Implications for

Patient Selection. Circulation. 2007 Jul 31.

165. Slaughter MS, Feldman CM, Sobieski MA, Silver MA, Martin MM, Kurien S,

Coyle LA, Pederson B. Utilization of acoustic signatures to identify HeartMate XVE

device end-of-life. J Heart Lung Transplant. 2007 Jun.

166. Slaughter MS, Tsui SS, El-Banayosy A, Sun BC, Kormos RL, Mueller DK, Massey

HT, Icenogle TB, Farrar DJ, Hill JD; IVAD Study Group. Results of a multicenter

clinical trial with the Thoratec Implantable Ventricular Assist Device. J Thorac

Cardiovasc Surg. 2007 Jun.

167. Slaughter MS, Sobieski MA, Martin M, Dia M, Silver MA. Home Discharge

Experience With the Thoratec TLC-II Portable Driver. ASAIO J. 2007 Mar-Apr.

168. Travis AR, Giridharan GA, Pantalos GM, Dowling RD, Prabhu SD, Slaughter MS,

Sobieski M, Undar A, Farrar DJ, Koenig SC. Vascular pulsatility in patients with a

pulsatile- or continuous-flow ventricular assist device. J Thorac Cardiovasc Surg.

2007 Feb.

169. Feldman CM, Silver MA, Sobieski MA, Slaughter MS. Management of Aortic

Insufficiency With Continuous Flow Left Ventricular Assist Devices: Bioprosthetic

Mark S. Slaughter, M.D. November 15, 2016

49

Valve Replacement. J Heart Lung Transplant. 2006 Dec.

170. Miller LW, Nelson KE, Bostic RR, Tong K, Slaughter MS, Long JW. Hospital costs

for left ventricular assist devices for destination therapy: lower costs for implantation

in the post-REMATCH era. J Heart Lung Transplant. 2006 Jul.

171. Slaughter MS, Sobieski MA, Koenig SC, Pappas PS, Tatooles AJ, Silver MA. Left

Ventricular Assist Device Weaning: Hemodynamic Response and Relationship to

Stroke Volume and Rate Reduction Protocols. ASAIO J. 2006 May-Jun.

172. McNicholas KW, Ivey TD, Metras J, Szentpetery S, Marra SW, Masters RG, Dilling

EW, Slaughter MS, Mack MJ. North American multicenter experience with the On-

X prosthetic heart valve. J Heart Valve Dis. 2006 Jan.

173. Sobieski MA 2nd, Pappas PS, Tatooles AJ, Slaughter MS. Embol-X intra-aortic

filtration system: capturing particulate emboli in the cardiac surgery patient. J Extra

Corpor Technol. 2005 Jun.

174. Slaughter MS. Destination therapy: the future is arriving. Congest Heart Fail. 2005

May-Jun.

175. Long JW, Kfoury AG, Slaughter MS, Silver M, Milano C, Rogers J, Delgado R,

Frazier OH. Long-Term, Destination Therapy With the HeartMate XVE Left

Ventricular Assist Device: Improved Outcomes Since the REMATCH Study. Congest

Heart Fail. 2005 May-Jun.

176. Sobieski MA 2nd, Slaughter MS, Hart DE, Pappas PS, Tatooles AJ. Prospective

study on cardiopulmonary bypass prime reduction and its effect on intraoperative

blood product and hemoconcentrator use. Perfusion. 2005 Jan.

177. Sobieski MA, George TA, Slaughter MS. The Thoratec Mobile Computer: Initial In-

Hospital and Outpatient Experience. ASAIO J. 2004 Jul-Aug.

178. Tatooles AJ, Pappas PS, Gordon PJ, Slaughter MS. Minimally invasive mitral valve

repair using the da Vinci robotic system. Ann Thorac Surg. 2004 Jun.

179. Slaughter M. Myocardial Recovery After Chronic Mechanical Assist Device

Support: Fact or Fiction? Congest Heart Fail. 2004 Mar-Apr.

180. Banbury MK, Kouchoukos NT, Allen KB, Slaughter MS, Berry G, Horvath KA. The

histologic characteristics of captured particulate emboli using the Embol-X intra-

aortic filter during cardiopulmonary bypass. Heart Surg Forum. 2003.

181. Sobieski MA 2nd, Slaughter MS, Hart DE, Pappas PS, Tatooles AJ. Peripheral

Cardiopulmonary Bypass With Modified Assisted Venous Drainage And

Transthoracic Aortic Crossclamp: Optimal Management For Robotic Mitral Valve

Mark S. Slaughter, M.D. November 15, 2016

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Repair. Perfusion. 2003 Sep.

182. Slaughter MS, Pappas P, Tatooles A. Percutaneous Endoscopic Gastrostomy Tube in

a Patient with a Left Ventricular Assist Device. ASAIO J. 2003 Sep-Oct.

183. Banbury MK, Kouchoukos NT, Allen KB, Slaughter MS, Weissman NJ, Berry GJ,

Horvath KA; ICEM 2000 Investigators. Emboli capture using the Embol-X

intraaortic filter in cardiac surgery: a multicentered randomized trial of 1,289

patients.Ann Thorac Surg. 2003 Aug.

184. Mussivand T, Harasaki H, Litwak K, Slaughter MS, Gray LA Jr, Dowling TR,

Mueller R, Masters RG, Hendry PJ, Beck-Da-silva L, Davies R, Haddad H, Mesana

TG, Keon WJ. In vivo evaluation of the biocompatibility of the totally implantable

ventricular assist device (HeartSaver VAD). ASAIO J. 2003 Jul-Aug.

185. Cianci P, Lonergan-Thomas H, Slaughter M, Silver MA. Current and Potential

Applications of Left Ventricular Assist Devices. J Cardiovasc Nurs. 2003 Jan-Mar.

186. Slaughter MS, Silver MA, Farrar DJ, Tatooles AJ, Pappas PS. A New Method of

Monitoring Recovery and Weaning the Thoratec Left Ventricular Assist Device. Ann

Thorac Surg. 2001 Jan.

187. Slaughter MS, Pappas PS, Tatooles AJ. Modified implant technique for the

pneumatic HeartMate left ventricular assist system. J Congestive Heart Failure &

Circulatory Support 1999.

188. Zelinger A, Pappas P, Slaughter M, Tatooles A, Bhan A. Limitations of screening

transthoracic echocardiography in assessing intracardiac injury due to cardiothoracic

trauma: a role for intraoperative TEE during initial surgical repair. Video J

Echocardiography 1999.

189. Slaughter MS, Gordon PJ, Roberts JC, Pappas, PS. An unusual case of hypoxia from

benzocaine-induced methemoglobinemia. Ann Thorac Surg. 1999 Jun.

190. Baldwin DR, Slaughter MS, Park S, McFalls E, Ward HB. Coronary bypass grafting

for single vessel coronary artery disease: a 17-year review with short and long-term

follow-up. Chest. 1998 Mar.

191. Slaughter MS, Gerchar DC, Pappas PS. Modified minimally invasive technique for

greater saphenous vein harvesting. Ann Thorac Surg. 1998 Feb.

192. Smith PC, Slaughter MS, Petty MG, Shumway SJ, Kshettry VR, Bolman RM 3rd.

Abdominal complications after lung transplantation. J Heart Lung Transplant. 1995

Jan-Feb.

193. Slaughter MS, Braunlin E, Bolman RM 3rd, Molina JE, Shumway SJ. Pediatric heart

transplantation: results of 2- and 5-year follow-up. J Heart Lung Transplant. 1994 Jul-

Aug.

Mark S. Slaughter, M.D. November 15, 2016

51

194. Slaughter MS, Kshettry VR, Smith PC, Foker JE. Internal mammary artery for

arterial pressure monitoring after pediatric cardiac operations. Ann Thorac Surg. 1993

Dec.

195. Slaughter MS, Olson MM, Lee JT Jr, Ward HB. A fifteen-year wound surveillance

study after coronary artery bypass. Ann Thorac Surg. 1993 Nov.

196. Pearce WH, Slaughter MS, LeMaire S, Salyapongse AN, Feinglass J, McCarthy WJ,

Yao JS. Aortic diameter as a function of age, gender, and body surface area. Surgery.

1993 Oct..

197. Slaughter MS, Nielsen K, Bolman RM 3rd. Extracorporeal membrane oxygenation

after lung or heart-lung transplantation. ASAIO J. 1993 Jul-Sep.

198. Slaughter MS, Pomerantz RA, Murad T, Hines JR. Infiltrating syringomatous

adenoma of the nipple. Surgery. 1992 Jun;111(6):711-3.

199. Brown PS Jr, Nath R, Votapka T, Slaughter M, Meyers SN, Talano JV, Joob A.

Traumatic ventricular septal defect and disruption of the descending thoracic aorta.

Ann Thorac Surg.1991 Jul;52(1): 143-4. No abstract available.

200. Sawchuck A, Canal D, Grosfeld JL, Slaughter M, Gardner G, O’Connor T, Behrman

D. Electrical pacing of the Roux limb resolves delayed gastric emptying. J Surg Res.

1987 Jun.

201. Sawchuk A, Canal D, Slaughter M, Bearman D, O’Connor T, Grosfeld JL. A

comparison between fructose 1, 6-diphosphate, glucose, or normal saline infusions

and species-specific blood exchange transfusions in the treatment of bowel ischemia.

Surgery. 1986 Oct.

Clinical Trials:

1. HeartWare 004A

A Prospective, Randomized, Controlled, Unblinded, 2014-Ongoing

Multi-Center Clinical Trial to Evaluate the HeartWare

Ventricular Assist Device System for Destination Therapy of Advanced Heart Failure

IRB#13.0593

2. PREVENT 2015-2016

Prevention of HeartMate II Pump Thrombosis through Clinical Management

(PREVENT)

IRB#14.1161

Mark S. Slaughter, M.D. November 15, 2016

52

3. LEVO-CTS 2015-Ongoing

A Double-Blind, Randomized, Placebo-controlled Study of Levosimendan in

Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery

Requiring Pulmonary By-pass;LEVO-CTS

IRB#15.0403

4. Momentum 3 2014-Ongoing

Multi-Center Study of MagLev Technology in Patients Undergoing MCS

Therapy with HeartMate 3

IRB#15.0347

5. LAAOS III 2015-Ongoing

Left Atrial Appendage Occlusion Study III

IRB#14.0085

6. HW-PAS-03 2014-2015

A Multi Center, Post Approval Study Providing Continued Evaluation and

Follow-up on Patients Who Received a HeartWare Ventricular Assist System

During IDE Trials for the Treatment of Advanced Heart Failure

IRB#13.0069

7. ROADMAP 2011- 2013

Risk Assessment and Comparative Effectiveness Of Left Ventricular Assist

Device and Medical Management in Ambulatory Heart Failure Patients

IRB#11.0529

8. CTSN

Evaluation of Outcomes Following Mitral Valve Repair/Replacement in 2010-2011

Severe Chronic Ischemic Mitral Regurgitation

NHLBI, NINDS & CIHR

IRB #10.0399

9. CTSN 2010-2011

Surgical Interventions for Moderate Ischemic Mitral Regurgitation

NHLBI, NINDS & CIHR

IRB #10.0398

10. LAAx, Inc. 2009-2011

Exclusion of the Left Atrial Appendange (LAA) with the LAAx, Inc.

TigerPaw System

University of Louisville

NCT00962702

11. Evaluation of the Levacor Ventricular Assist Device as a Bridge to Cardiac 2010 – 2011

Transplantation Clinical Trial

Mark S. Slaughter, M.D. November 15, 2016

53

University of Louisville

IRB#09.0494

12. Procedures and Outcomes in Heart Transplantation: 25 Years 2009 – 2010

Experience at Jewish Hospital

IRB #09.0362

13. Levitroni 2009-2010

CentriMag VAS: Failure-to-Wean from Cardiopulmonary Bypass Trial

IRB #09.0159

14. Retrospective review of patients with surgical treatment 2008-2011

of advanced heart failure

Principle Investigator

15. SUNSHINE HEART, Incorporated 2008-Present

C-Pulse™ Implantable Counterpulsation Pump (ICP)

U.S. Feasibility Study

IRB #08.0487

16. HeartWare, Inc. 2008-2009

Evaluation of the HearWare Left Ventricular Assist Device (LVAD) System for the

Treatment of Advanced Heart Failure (Protocol Number HW003, Revision 4.0)

IRB #08.0453/IDE #G070199

17. Myocardial Regeneration Using Cardiac Stem Cells Harvested 2008 – Present

From Right Atrial Appendages in Patients with Ischemic Cardiomyopathy

IRB #062.067

18. Merck A Randomized, Multicenter, Double-Blind, Group-Sequential 2008-Present

Study to Evaluate the Efficacy, Immunogenicity, and Safety of a Single Dose

of Merck 0657nl Staphylococcusaureus Vaccine (V710) in Adult Patients

Scheduled for Cardiothoracic Surgery.IRB #

19. NovoNordisk 2008-Present

A Prospective, randomized, double-blind, placebo controlled, parallel group, multi-

center Study to evaluate the efficacy of activated recombinant Factor VII for early control of

hemorrhage in high-risk cardiac surgery. IRB #

20. CVRX: Rheos Baroreflex Hypertension Therapy System Pivotal Trial. 2007–Present

IRB # 4325

21. CVRX: Rheos Baroreflex Hypertension Therapy System Feasibility Trial. 2006-2007

IRB # 4232

Mark S. Slaughter, M.D. November 15, 2016

54

22. SCCOR: The Epidemiology of Bleeding and Clotting in Patients 2006-Present

Undergoing Heart Transplantation of Left Ventricular Assist Devices.

IRB # 4108

23. SCCOR: The Epidemiology of Ventricular Assist Devices – Related 2006-Present

Infections.

IRB # 4107

24. Momentum Trial: Multicenter Trial of the Orqis CRS for the Enhanced 2006-Present

Treatment of CHF Unresponsive to Medical Therapy.

IRB # 4014

25. A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study 2005-Present

of the Safety and Efficacy of Human Recombinant Soluable Complement

Receptor Type 1 (TP10) in Adult Women Undergoing Cardiopulmonary Bypass Surgery.

IRB # 3907

26. HeartMate II LVAS Pivotal Study. 2005-Present

IRB # 3879

27. Pathophysiologic Benefits of Continuous and Pulsatile Ventricular 2004-Present

Assist Trial.

IRB # 3805

28. ZymoGenetics

2003

A Phase I Study of the Safety and Pharmacokinetics of Recombinant Factor XIII-

Administration in Patients Undergoing First-time Cardiopulmonary Bypass for Myocardial

Revascularization.

29. Mitral Valve Replacement using the daVinci Surgical System. 2003-Present

IRB # 3524

30. HeartMate LVAS Cardiogenic Shock Complicating An 2003-Present

Acute Myocardial Infarction IRB # 3523

31. A Study to Evaluate Safety and Performance of the Sutureless 2003-2004

Anastomotic System (SAS) for Creating Anastomosis.

IRB # 3522

32. Thoratec Destination Therapy Registry. 2003-Present

IRB # 3519

33. Coverge – Study to Evaluate Safety and Performance of the 2003-2005

Sutureless Anastomotic System (SAS) for Creating Anastomosis

Principal Investigator

34. Prospective, Non-randomized, Non-blinded, Multi-Center, Clinical 2002-2003

Mark S. Slaughter, M.D. November 15, 2016

55

Evaluation of the Syncrus Internal Cardioversion System in the Treatment of Patients

who develop Post-Operative Atrial Fibrillation. IRB # 3409

35. Prevent IV: A Phase III, Multi-Center Randomized, Double Blind, 2002-2004

Placebo-Controlled Trial of the Ex Vivo treatment with CGT003 of Coronary Artery Vein

grafts in Patients Undergoing Coronary Artery Bypass Graft Procedures.

IRB # 3404

36. Atrial Septal Defect Repair using the daVinciSurgical System.

2002

IRB # 0070

37. Clinical Evaluation of the Thoratec Implantable Ventricular Assist 2002-2004

Device (IVAD). Principal Investigator.

IRB # 3307

38. ISHLT Mechanical Circulatory Support Device Database. 2002-Present

Principal Investigator.

IRB # 3300

39. Clinical Evaluation of Acorn Cardiac Support Device Therapy in Patients 2001-2004

with Dilated Cardiomyopathy - U.S. Randomized trial Principal Investigator.

IRB # 3211

40. Mitral Valve Repair Using the daVinci Surgical System. 2001-2003

Multi-Center Clinical Trial. Principal Investigator.

IRB # 3200

41. Pre-Clinical Animal Testing of HeartSaver LVAD. Chronic In-vivo and 2001-2002

Acute Performance Testing. Principal Investigator.

ACC # 01-079

42. Comparison of LVAD Weaning Methods and its Effect on Left Ventricular 2001

Wall Stress. Principal Investigator.ACC # 01-049

43. Effects of Chronic Mechanical Unloading by a Left Ventricular Assist 2001-2003

Device on Myofilament Activation in Heart Failure. Principal Investigator.

IRB # 3184

44. Home Discharge Clinical Evaluation of the Thoratec TLC-II Driver in the 2001-2004

VAD System. Principal Investigator.

IRB# 0047

45. EMBOL-X Inter-aortic Filtration System. Principal Investigator. 2000-Oct 2002

MIC Project # 912

46. Aria Coronary Artery Bypass Graft U.S. Phase I Trial. AEGIS/U.S. 1999-July 2000

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Clinical Trial. Principal Investigator.

MIC Project # 893

47. On-X Prosthetic Heart Valve Aortic and Mitral Models. Phase 1999-Present

III trial. Principal Investigator.

MIC Project # 864

48. Thoratec TLC-II Portable Driver System. Principal Investigator. 1999-2000

MIC Project # 849

49. Pumpless ECMO for ARDS. Principal Investigator. 1999-2000

Medtronic equipment grant support $3000

50. Suppression of the Systemic Inflammatory Response of Cardiopulmonary 1999-2000

Bypass and its Effect on Clinical Outcomes in Patients Undergoing Coronary Artery

bypass Grafting. Principal Investigator. Med Fund Grant Support $30,000.

MIC Project # 835

51. C-SMART (Cardiomyoplasty - Skeletal Muscle Assist Randomized Trial). 1998

Phase III trial of Dynamic Myoplasty for Congestive Heart Failure. Principal Investigator.

MIC Project # 814

52. The Use of Leukine to Stimulate Healing of Leg wounds After Coronary 1998-1999

Artery Bypass Graft Surgery. Investigator. Immunex Grant Support $20,000.

MIC Project # 802

53. A study of the Conversion Efficacy and Safety of Repeated Intravenous 1996-1997

Doses of Ibutilide in Patients with Atrial Flutter or Atrial Fibrillation Following Coronary

Artery Bypass Surgery. Investigator.

Abstracts: 1. “Cardiac Gene Expression Profile Distinguishes African-American and European-American Heart

Failure Patients” Halder I, Causer V, McTiernan C, Lemster B, Ramani R, Prabhu S, Slaughter M, Dries D, Tseng G, McNamara D, ACC Conference, Chicago. April 2016

2. “Long-term Follow up of the Impact of Cardiac Resynchronization Therapy on Clinical and

Arrhythmic Outcomes in Continuous Flow Left Ventricular Assist Device Recipients” Familtsev D, Hottigoudar R, Ghotra A, Slaughter M, Trivedi J, Sutton B, Deam G, McCants K, Lenneman A, Birks E, Gopinathannair R. 2015 May, Heart Rhythm Society. (Oral)

3. “Correlating Modified Surgical MAZE lesions in the Left Atrium with Propensity of Atrial Tachycardia

Development During Follow-up” Mar P, Lakkireddy D, Tu Y, Gunda S, Lenneman C, Slaughter M, Trivedi J, Biase L, Natale A, Gopinathannair R. 2015 May, Heart Rhythm Society. (Oral)

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4. “Heart Transplant Survival Based on Recipient and Donor Risk Scoring: A UNOS Database Analysis” Trivedi J, Ising M, Cheng A, Lenneman A, Birks E, Slaughter MS 2015 April, International Society for Heart and Lung Transplantation Annual Meeting. (Oral)

5. “Impact of Cardiac Resynchronization Therapy on Clinical Outcomes in Patients with Continuous-

Flow Left Ventricular Assist Devices” R. Gopinathannair, E. Birks, J. Trivedi, K. McCants, B. Sutton, A. Deam, M. Slaughter, R. Hottigoudar 2015 March, Journal of Cardiac Failure.

6. “Demonstration of Low Frequency Speed Modulation of Miniature Rotary Blood Pumps in a Large

Animal Model” K. Soucy, G. Guruprasad, M. Sobieski, Slaughter MS, Koenig S. 2014 October, Biomedical Engineering Society Annual Meeting. (Oral)

7. “Preoperative Aspirin Use and its Effect on Adverse Events in Patients Undergoing Cardiac Surgery”

Huang J, Donneyong M, Trivedi J, Slaughter MS. 2014 April, Society of Cardiovascular Anesthesiologists Annual Meeting, New Orleans, LA. (ePoster presentation)

8. “Myocardial Regeneration and Recovery with Extracellular Matrix and LVAD Support”. 34th Annual

ISHLT Meeting. April 13, 2014. (Oral)

9. “Comparison of Total Artificial Heart and Biventricular Assist Device Support as Bridge-to-Transplantation” 34th Annual ISHLT Meeting. April 11, 2014 (Oral-Allen Cheng)

10. “Early Post-op anticoagulations: Is It Needed and What to Use?” 34th Annual ISHLT meeting. April 10,

2014, San Diego, CA. (Oral)

11. HeartWare” Small group Session ISHLT Academy MCS Meeting pre 34th Annual ISHLT Meeting. April 8th, 2014. San Diego CA (oral)

12. “Tailoring Pumps to Patients” Surgical Considerations- ISHLT Academy MCS Meeting- 34th Annual

ISHLT Meeting. April 7th, 2014. San Diego CA (oral)

13. “Extended Extra-aortic Counterpulsation Support with C-Pulse Device Does Not Alter Aortic Wall Structure” 34th Annual ISHLT Meeting. April 11, 2014. (Poster)

14. “Impact of Device Design and Patient Management on the Incidence of Neurologic Events after

HVAD Left Ventricular Assist Device”. 34th Annual ISHLT Meeting. April 11, 2014. (Oral) 15. Slaughter MS, Cheng A. Left Ventricular and Vascular Biomechanics in Advanced Heart Failure

Patients Supported by Continuous and Pulsatile Left Ventricular Assist Devices. 9th Annual Academic Surgical Congress. February 4-6, 2014. (Poster)

16. Goldstein DJ, Aaronson KD, Tatooles A, Silvestry SC, Jeevanandam V, Gordon RA, Hathaway DR,

Najarian KB, Slaughter MS. “Gastrointestinal Bleeding in Recipients of the HeartWare Ventricular Assist System”. AHA Scientific Sessions 2013 Annual Meeting. November 19, 2013. (Oral Session)

17. Milano CA, Pagani FD, Slaughter MS, Pham,DT, Hathaway DR, Najarian KB, Aaronson KD. “Clinical

Outcomes Following Implantation of a Centrifugal Flow Left-Ventricular Assist Device and

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Concomitant Cardiac Valve Procedures”. AHA Scientific Session 2013 Annual Meeting. November 19, 2013. (Oral Session)

18. Slaughter MS. “Universal Apical Access System for Left Ventricular Assist Implantation: A

Preliminary Feasibility Study”. ISRBP 2013 Annual Meeting. September 27, 2013. (Abstract accepted July for Oral Presentation)

19. Hottigoudar R, Slaughter MS, Birks EJ. “Cardiac Resynchronization Therapy does not Offer Additive

Benefit over ICD in Patients with Continuous Flow LVAD.” 34th Annual Heart Rhythm 2013, Denver, CO. (Abstract accepted February 2013)(Poster)

20. Lenneman AJ, Combs P, Rhode S, Vessels K, McCants K, Singh R, Birks E, Slaughter MS.

“Management and Outcomes of Ventricular Assist Device Patients with Suspected Pump Thrombosis. 33rd ISHLT Annual Meeting. Montreal, CAN. (Poster)

21. Jorde UP, Khushwaha SS, Tatooles AJ, Naka Y, Bhat G, Long JW, Horstmanshof D, Kormos RL,

Teuteberg JJ, Slaughter MS, Birks EJ, Farrar DJ, Park, SJ. “Two-Year Outcomes in the Destination Therapy Post-FDA-Approval Study with a Continuous Flow LVAD: Prospective Study Using the INTERMACS Registry.” 33rd International Society of Heart & Lung Transplantation Annual Meeting, Montral CAN. (Abstract accepted January 2013) (Oral)

22. Combs PS, Raheia P, Slaughter MS, Birks EJ, “Predisposition to Infection and Bleeding in Mechanical

assist Devices (LVADs) Recipients after Dental procedures: A single Center Experience” 33rd International Society of Heart & Lung Transplantation Annual Meeting, Montral CAN. (Abstract accepted January 2013) (Oral)

23. Ranjit J, Aaronson K, Pae W, Acker M, Hathaway D, Najarian K, Slaughter MS. “Driveline Infections

and Sepsis in Patients Receiving the HVAD System as a Left-Ventricular Assist Device” 33rd International Society of Heart and Lung Transplantation Annual Meeting, Montreal CAN . (Abstract accepted January, 2013) (Oral)

24. Ranjit J, Aaronson K, Pagani F, Hathaway D, Swartz M, Najarian K, Slaughter MS. “Impact of

Demographic and On-Pump Factors on Post-Transplant Survival Following Support with the HVAS System” 33rd International Society of Heart and Lung Transplantation Annual Meeting, Montreal CAN . (Abstract accepted January, 2013) (Oral)

25. Combs PS, Sobieski ME, Trivedi JR, Creamer EF, McCants KC, Birks EJ, Singh R, Slaughter MS.

“Education level and insurance do not impact mid-term survival after left ventricular assist device implantation” 33rd International Society of Heart and Lung Transplantation Annual Meeting, Montreal CAN . (Abstract accepted January, 2013) (Oral)

26. Aggarwal A, Bhat G, Tatooles G, Slaughter MS, Jorde U, Brewer R, Chen L, Farrar D, Sundareswaran

K. “Racial Differences in over 1000 Patients with Continuous Flow Left Ventricular Assist Devices” 33rd International Society of Heart and Lung Transplantation Annual Meeting, Montreal CAN . (Abstract accepted January, 2013) (Poster)

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27. Donneyoung, M, Trivedi JR, Williams ML, Slaughter MS. “Association of Prior Implantation of Heartmate II Left Ventricular Assistive Device With Post-Heart Transplant Mortality” 33rd International Society of Heart and Lung Transplantation Annual Meeting, Montreal CAN.. (Abstract accepted January, 2013) (Oral)

28. McGee Jr EC, Aaronson K, Birks EJ, Boyce SW, Cotts WG, Najjar SS, Pagani FD, Hathaway D, Jacoski

MV, Najarian KB, Slaughter MS. “An Examination of Survival by Sex in the HVAD BTT and CAP Trials.” Accepted for American Heart Association 2012 Scientific Trials, Los Angeles CA, November 04, 2012 (Poster)

29. Cohn W, Slaughter MS, Parkin R, LaFontaine D, Peters W, “Transcutaneous-Powered

Electrohydraulic Counterpulsation System For Ambulatory Non-Obligatory Chronic Heart Failure Treatment” TCT 2012 Conference, Miami Beach, FL, October 23, 2012 (Poster).

30. Keeling WB, Williams ML, Slaughter MS, Zhao S, Puskas JD. Off-Pump and On-Pump Coronary

Revascularization in Patients with Low Ejection Fraction: A Report from the STS National Database. STS Annual Meeting, January 2013. (Abstract accepted August 2012).

31. Birks EJ, Slaughter MS, Boyce S, McGee E, Cotts WG, Najjar SS, Pagani FD, Hathaway D, Jacoski MJ,

Najarian K, Aaronson KD. “Improved Quality of Life and Functional Capacity for Patients receiving the HVAD® Pump” Heartware QOL abstract (accepted as an oral presentation at the AHA, August 2012)

32. Bourque K, Cotter C, Dague C, Sobieski M, Koenig S, Slaughter MS. “In Vivo Evaluation of LVAD

Artificial Pulse Parameters and Synchrony with the Native Heart.” 20th Congress of the International Society for Rotary Blood Pumps Meeting, Istanbul, Turkey, September 20-22, 2012. (Abstract submitted August 2012)

33. Keeling WB, Trivedi J, Williamitis C, Singh R, Slaughter MS, Williams ML. “Preoperative Anemia and

Low Body Mass Index but Not Female Gender as Risk Factors for Increased Transfusion Following Isolated Coronary Artery Bypass Grafting.” American Heart Association Scientific Sessions, Los Angeles, CA, November 2012 (Abstract submitted June 2012)

34. Soucy KG, CJ Benzinger, AC Ansert, KP Holley, TC Spalding, GA Giridharan, MA Sobieski, MS

Slaughter, and SC Koenig. Development of an Apical Left Ventricular (ALV) cannula system for aortic valve bypass. Submitted to Biomedical Engineering Society (BMES) annual conference, October 24-27, 2012, Atlanta, GA.

35. Soucy KG, JD Graham, CJ Benzinger, GA Giridharan, MA Sobieski, SC Koenig, and MS Slaughter. Flow

dynamics and hemocompatibility of an apical left ventricular cannula. 58th ASAIO Conference, June 14-17, 2012, San Francisco, CA.

36. Buller M, Sobieski M, Soucy K, Giridharan G, Slaughter MS, Investigation of Myocardial Recovery in a

Chronic Ischemic Heart Failure Bovine Model. European Society of Artificial Organs (submitted April 2012)

37. Hottigoudar RU, Deam AG, Birks E, McCants K, Slaughter MS, Gopinathannair R. Catheter Ablation

of Atrial Flutter in Patients with HeartMateII Left Ventricular Assist Device Improves Symptoms of

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Right Ventricular Dysfunction. International Society of Heart and Lung Transplantation Annual Meeting, Prague, Czech Republic April, 2012. (poster)

38. Sobieski M, Schwartz S, Trivedi J, Williams ML, Slaughter MS, Use of Novel Thrombosis Index of Risk

(TIR) as Indicator for Left Ventricular Assist Device (LVAD) Thrombosis. International Society of Heart and Lung Transplantation Annual Meeting, Prague, Czech Republic April, 2012. (poster)

39. Trivedi JR, Slaughter MS, McCants KC, Birks EJ, Meyer A, Williams ML. Panel Reactive Antibody in

Bridge to Transplant Left Ventricular Assist Device Patients: Impact on Patient Survival after Cardiac Transplant. International Society of Heart and Lung Transplantation Annual Meeting, Prague, Czech Republic April, 2012. (oral)

40. Adamson RM, John R, Goldstein D, Park SJ, Milano CA, Tatooles AJ, Sundareswaran KS, Farrar DJ,

Slaughter MS. Heparin May not be needed as a Transition to long term Warfarin Therapy in LVAD Destination Therapy Patients. International Society of Heart and Lung Transplantation Annual Meeting (Abstract Submitted November 2011).

41. Beache GM, El-Baz AS, Chug AR, Loughran J, Elmore JB, Bolli R, Leri A, Kajstura J, Anversa P,

Slaughter MS. Visualization of Autologous Adult Cardiac Stem Cell Effect in Humans using Multi-modal MRI Characterization. Accepted for Annual Meeting of the Society of Cardiovascular Medical Research, February 2012. (Abstract submitted October 2011)

42. Dowling RD, Spence Pa, Warren S, Tompkins L, Sandova M, Giridharan GA, Sherwood, Gratz E,

Spanier G, Lederer L, Bruck S, Slaughter M, Koenig SC. Development of a Long-Term Superficial Device for Partial Circulatory Support. Accepted for HFSA Meeting, Boston, MA, September 2011.

43. Issing M, Sobieski MA, Slaughter MS, Koenig SC, Guruprasad GA. Hemodynamic Responses to

Continous Flow LVAD Speed Modulation in Computer Simulation and in-vitro Mock Loop Studies. Accepted for Annual Meeting of The International Society for Rotary Blood Pumps, Louisville, KY, September, 2011 (Poster)

44. Soucy K, Koenig S, Sobieski M, Slaughter M, Giridharan G. “Fault Detection Algorithm for Rotary

Ventricular Assist Devices.” 2011 Biomedical Engineering Society Annual Meeting, Hartford, CT, October 12 – 15, 2011 (abstract accepted June 2011)

45. Bartoli C, Brittain K, Sobieski M, Giridharan G, Wead W, Dowling R, Slaughter M, Prabhu S, Koenig S.

“Acute Hemodynamic Responses to Partial vs. Full Unloading of the Heart with a Continuous-Flow LVAD.” 2011 Biomedical Engineering Society Annual Meeting, Hartford, CT, October 12 – 15, 2011 (abstract accepted June 2011)

46. Ising M, Koenig S, Sobieski M, Slaughter M, Giridharan G. “Flow Modulation Algorithms for Intra-

Aortic Rotary Blood Pumps to Reduce Coronary Steal.” 2011 Biomedical Engineering Society Annual Meeting, Hartford, CT, October 12 – 15, 2011 (abstract accepted June 2011) PMID:23644613

47. Brisco MA, Sundareswaran KS, Milano CA, Feldman D, Ewald G, Slaughter M, Farrar D, Goldberg LG.

“Atrial Arrhythmias in Patients with Continuous-Flow Left Ventricular Assist Devices (CF-LVADs): The

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Incidence, the Risk, the Consequences.” American Heart Association (AHA) Scientific Sessions, Orlando, FL, November 12 – 16, 2011

48. Brisco MA, Sundareswaran KS, Milano CA, Feldman D, Eewald G, Slaughter M, Farrar D, Goldberg LR. “Risk and Impact of Early and Late Ventricular Arrhythmias in Patients with Continuous-Flow Left Ventricular Assist Devices (CF-LVADs). American Heart Association (AHA) Scientific Sessions, Orlando, FL, November 12 – 16, 2011 (Abstract Submitted June 2011)

49. Williams ML, Trivedi JR, He X, Slaughter MS. “STS Database Report: Lower Pre-operative

Hematocrit Predicts Adverse Outcomes After Coronary Artery Bypass Graft Surgery and Helps Explain Gender Differences.” Southern Thoracic Surgical Association Annual Meeting, San Antonio, TX, November, 2011. (Abstract Submitted April 2011)

50. Williams ML, Trivedi JR, Meyer AL, Davis J, Slaughter MS. “Driveline Infection in Bridge to Transplant Patients: Should Transplant Status be Upgraded?” Southern Thoracic Surgical Association Annual Meeting, San Antonio, TX, November, 2011. (Abstract Submitted April 2011)

51. Slater AD, Coffee A, Pappas P, Bresticker M, Pagni S, Beckman D, Wozniak T, Greason K, Ganzel BL, Rousou A, Austgen C, Stoddard M, Slaughter MS. “Prospective, Multicenter, Single Arm Investigation of a Novel Externally Applied Left Atrial Appendage (LAA) Occlusion Device.” Southern Thoracic Surgical Association Annual Meeting, San Antonio, TX, November 11, 2011. (Abstract Accepted May 2011)

52. Williams ML, Trivedi JR, Birks EJ, McCants KC, Sobieski MA, Slaughter MS. “Patient Outcomes after

Pump Stoppage in Continuous Flow Left Ventricular Assist Devices.” Southern Thoracic Surgical Association Annual Meeting, San Antonio, TX, November, 2011. (Abstract Submitted April 2011)

53. Williams ML, Trivedi JR, Slater AD, Pagni S, Ganzel BL, Slaughter MS. “Poor Mid-term Outcomes for

Surgery for Active Infective Endocarditis in Chronic Renal Failure Patients.” Southern Thoracic Surgical Association Annual Meeting, San Antonio, TX, November, 2011. (Abstract Submitted April 2011)

54. Cannon RM, Trivedi JR, Bland JN, Dwivedi A, Ross CB, Slaughter MS, Richardson JD, Williams ML.

“Traditional Open Repair of Traumatic Thoracic Aortic Injury Remains Relevant in the Endovascular Era.” Abstract Accepted to American College of Surgeons Annual Meeting, October 2011.

55. Slaughter MS, Birks E, Sobieski M, Ising m, Sherwood L, Hawes M, et al. “Pre-clinical GLP study of Impella 2.5 (Abiomed, Danvers, MA) for 5-day left ventricular (LV) support.” Abstract Accepted for ASAIO Annual Meeting, Washington, D.C., June, 2011.

56. Giridharan GA, Bartoli C, Soucy K, Sobieski MA, Koenig SC, Slaughter MS. Effects of Pulsatile Flow

and Continuous Flow Ventricular Assist Device Failure on Hemodynamics and End-Organ Blood Flow. Abstract Accepted for ASAIO 2011, Washington, D.C., June 2011.

57. Graham JD, Sharp MK, Koeniq SC, Giridharan G, Sobieski MA, Slaughter MS. Treatment of Severe

Aortic Stenosis: Development and Feasibility Testing of an Aortic Valve Bypass Apical Cannula. Proceedings of the ASME 2011 Summer Bioengineering Conference, Farmington, PA, June 22-25, 2011.

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58. Cowger J, Sundareswaran K, Rogers JG, Park SJ, Pagani FD, Bhat G, Jaski B, Farrar DJ, Slaughter MS.

The HeartMate II Risk Score: Predicting Survival in Candidates for Left Ventricular assist Device Support. Abstract Accepted for ISHLT, San Diego, CA, April 2011.

59. Sai-Sudhakar CB, Brewer RJ, Emani S, Slaughter MS, ravi Y, Sunderswaran, Farrar DJ, John R. Patients with Low Compared to High Body Mass Index Gain More Weight After Continuous Flow LVAD Implant. Abstract Accepted for ISHLT, San Diego, CA, April 2011.

60. Slaughter MS, Aaronson KD, Boyce S, Miller LW, McGee EC, Cotts WG, Acker MA, Jessup ML, Gregoric ID, Loalka P, Frazier OH, Jeevandandam V, Anderson AS, Kormos RL, Teuteberg JJ, Pagani FD, Bittman RM, Hathaway DR. HVAD BTT Pivotal Trial and Continued Access Program (ADVANCE): Interim Report of the Expanded Study. Abstract Accepted for ISHLT Meeting, San Diego, CA, April 15, 2011.

61. “Continuous Flow Ventricular Assist Devices Are Associated With Increased Gastrontestinal

Hemorrhage.” Cannon RM, Trivedi JR, Davis EG, McMasters KM, Slaughter MS. Quick Shot Presentation at Southwestern Surgical Congress, Honolulu, HI, April 2011.

62. Pierson RN, Slaughter MS. HVAD BTT Pivotal Trial and Continued Access Program (ADVANCE):

Interim Report of the Expanded Study. Abstract accepted for ISHLT Meeting, San Diego, CA, April 15, 2011.

63. Birks EJ, Combs P, Vessels K, Rhode S, Prabhu S, Williams M, McCants K, Slaughter M. An Analysis of the Capacity Required and Typical Clinical Problems Encountered With An Expanding BTT and DT VAD Program. Abstract Accepted for ISHLT Meeting, April 2011, San Diego, CA.

64. Starling R, Meyer DM, Martin T, Slaughter MS, Bonde P. National Trends in Readmission (REA) Rates Following Left Ventricular Assist Device (LVAD) Therapy. Abstract Accepted for ISHLT Meeting, San Diego, CA, April 14, 2011.

65. Levy W, Hathaway D, Miller L, Boyce S, Cotts W, McGee E, Jessup M, Acker M, Slaughter MS, Aaronson K. Application of the Seattle Heart Failure Model to the HeartWare Bridge to Transplant US Trial. ACC 2011 Scientific Session. April 2-5, 2011. New Orleans, LA.

66. Park SJ, Milano CA, Tatooles AJ, Rogers JG, Adamson RM, Steldley DE, Ewald GA, Farrar DJ, Slaughter

MS. Outcomes in Advanced Heart Failure with Left Ventricular Assist Devices for Destination Therapy. AHA Scientific Session 2010, November 16, 2010, Chicago, IL.

67. Rogers J, Tatooles A, Park SJ, Steidley E, Horstmanshof D, Pae W, Starling R, Farrar D, Slaughter, MS.

Outcomes of Mechnical Circulatory Support for Destination Therapy in NYHA Class IIIB Patients. AHA 2010 Scientific Sessions. Nov. 13-17. Chicago, IL

68. Slaughter MS. Heart Transplant Vs. Left Ventricular Assist Device (LVAD) in Heart Transplant Eligible Patients. STSA 57th Annual Meeting. Nov. 3-6, 2010. Orlando, FL.

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69. Pagni, S, Dwivedi AJ, Ganzel BJ, Williams, ML, Trivedi, JR, Mascio CE, Ross C, Slaughter, MS. Thoracic Aortic Mobile Thrombus (TAMT): Is There a Role for Early Surgical Intervention? AATS Aortic Symposium. April 29-30, 2010. New York, NY

70. Williams ML, Ganzel B, Slater D, Slaughter M, Edmonds H, Pagni S. Antegrade versus Retrograde Cerebral Perfusion in Ascending Aortic Dissection. AATS Aortic Syposium. April 29-30, 2010. New York, NY.

71. Slaughter MS, Giridharan GA, Aggarwal S, Sobieski M, Tamez D, LaRose J, Sherwood L, Koenig SC.

Design and Feasibility Testing of a Miniaturized Transapical Mechanical Circulatory Support Device: MVAD. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

72. Slaughter MS, Rogers JG, Blue L, Lodge AJ, Tatooles AJ, Bhat G, Sobieski M, Milano CA. Destination

Therapy: Improving Outcomes with Continuous Flow LVADs. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

73. Moazami N, Sun B, Milano C, John R, Conte J, Adamson R, Pagani F, Frazier OH, Farrar D, Slaughter

MS. Pump Replacement for LVAD Failure Can Be Done Safely and Is Associated with Low Mortality. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

74. Slaughter MS, Bostic R, Rogers JG, Russo MJ, Miller LW. Changing Costs of Mechanical Circulatory

Support: Impact of Era and Device. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

75. Coyle LA, Gallagher CT, Bhat G, Pappas PS, Slaughter MS, Tattoles AJ. Quality of Life in Patients

Supported Two Years with a Continuous Flow Left Ventricular Assist Device as Destination Therapy. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

76. Aggarwal S, Luftman K, Bowles R, McCants K, Prabhu S, Dowling RD, Slaughter MS. Mid-Term

Results of Campath Induction and Steroid-free Maintenance Immunosuppression in Cardiac Transplantation. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

77. Petrucci, R, Russell S, Gallagher C, Dordunoo D, Sun B, Yanssens T, Rogers J, Blue L, Jafar M, Frazier OH, Farrar D, and Slaughter MS. Neurocognitive evaluation of destination therapy patients receiving continuous flow left ventricular assist devices. International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

78. Park, SJ., Naftel, DC, Slaughter, MS, Sobieski, MA, Staley, LL, Tallaj, JA, Baldwin, T, Kirklin, JK.

Reducing Adverse Neurological Events in LVAD Patients: Pulsatile vs. Continuous flow? International Society for Heart and Lung Transplantation. April 21-24, 2010; Chicago, IL.

79. Aranda JM, Rogers JG, Aronson KD, Boyle AJ, Russell SD, Edwards B, Zucker MJ, Klodell CT, Sundareswaran KS, Farrar DJ, Slaughter, MS. Quality of Life Improvements are Greater in Destination Therapy than Bridge to Transplant Patients with a Continuous Flow Left Ventricular Assist Device. ACC.10 Meeting, Atlanta, GA. October 2, 2009.

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80. Pantalos G, Ayers C, Rhode S, Haus R, Dowling R, Aggarwal S, Slaughter M. A New Method for Fixation and Stabilization of a Clinical Ventricular Assist Device Percutaneous Lead Heart Failure Society of America. September 13-16, 2009, Boston, MA.

81. Slaughter MS, Ising MS, Tamez D, O'Driscoll G,Voskoboynikov N, Bartoli CR, et al. Reappearance of a Normal Circadian Rhythm after Ventricular Assist Device Implantation Heart Failure Society of America. September 13-16, 2009, Boston, MA.

82. Starling RC, Slaughter MS. Postoperative Heparin Is Not Required in Transitioning Patients with

HeartMate II LVAD to Long Term Warfarin Therapy ISHLT 29th Annual Meeting and Scientific Sessions. April 23, 2009. Paris, France.

83. Bhat G, Slaughter MS. Right Failure after HeartMate II Left Ventricular Assist Device Implantation ISHLT 29th Annual Meeting and Scientific Sessions. April 22-25, 2009. Paris, France.

84. Kimovec M, Boarden W, Slaughter M, Sobieski M, Grutsch R. Anethesia for Patients with Continuous Flow Ventricular Assist Devices for Non-Cardiac Surgery.American Society of Anesthesiologists. Orlando, FL. October, 2008.

85. Pisano C, Nutter A, Perino B, Ziebarth C, Cooke G, Slaughter MS, Silver M. Can We Detect Fatal Heart Failure? HFSA 12th Annual Scientific Meeting. September 21-24, 2008. Toronto, ON, Canada. (Accepted for Presentation.)

86. Slaughter MS, Sobieski MA, Giridharan GA, Pantalos GM, Dowling RD, Prabhu SD, Farrar DJ, Koenig

SC. Intraoperative Evaluation of the Heartmate II Flow Estimator. ASAIO 54th Annual Conference. June 21, 2008. San Francisco, CA (Accepted for Moderated Poster Session.)

87. Slaughter M, Coyle L, Gallagher C, Kurien S, Sobieski M. Destination Therapy: Long Term Outcomes

in Patients with BMI Greater Than 30. ASAIO 54th Annual Conference. June 21, 2008. San Francisco, CA (Accepted for Moderated Poster Session.)

88. Spence PA, Giridharan GA, Wilson G, Dowling RD, Slaughter MS, Sobieski MA, Koenig SC. Acute Hemodynamic Efficacy of a 32-ml Counterpulsation Device During Pharmacologically Induced Hypotension, Hypertension and Heart Failure in Calves. ASAIO 54th Annual Conference. June 20, 2008. San Francisco, CA (Accepted for Slide Session Presentation.)

89. Slaughter M, Sobieski M, Martin M, Kurien S, Coyle L, Graham J, Horrell T, Pederson B. Evaluation of Acoustic Signatures for Hemodynamic Management of Flow Rates in the Heartmate II Flow Estimator. ASAIO 54th Annual Conference. June 20, 2008. San Francisco, CA (Accepted for Slide Session Presentation.)

90. Slaughter M, Coyle L, Kurien S, Horrell T, Graham J, Sobieski M. HeartMate XVE Device End-Of-Life: Results of XVE to HMII Device Exchange. ASAIO 54th Annual Conference. June 20, 2008. San Francisco, CA (Accepted for Slide Session Presentation.)

91. Slaughter M, Sobieski M, Graham J, Horrell T, Pederson B. Evaluation of New Technology: To Reduce

Platelet Adhesion and Coverage of Pyrolitic Carbon Surfaces. ASAIO 54th Annual Conference. June 19, 2008. San Francisco, CA (Accepted for Slide Session Presentation.)

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92. Giridharan GA, Slaughter MS, Sobieski MA, Dowling RD, Aggarwal S, Prabhu SD, Pantalos GM, Farrar

D, Koenig SC. LVAD Support Increases Transvalvular Pressure Gradient. ASAIO 54th Annual Conference. June 19, 2008. San Francisco, CA (Accepted for Slide Session Presentation)

93. Goldstein D, Naka Y, Icenogle T, Slaughter M, Pagani F, Choe J Rose E, Desvigne-Nickens P, Parides M, Rawiel U, Guerchicoff A, Ascheim D, Moskowitz A, Gelijns A, Schmidt AM. The Epidemiology of Bleeding and Clotting in Pulsatile and Continuous Flow LVAD Patients. ISHLT 28th Annual Meeting & Scientific Sessions. April 10, 2008. Boston, MA (Accepted for Oral Presentation.)

94. Slaughter MS, Sobieski MA, Graham JD, Horrell T, Pappas PS, Tatooles AJ, Rao GH, Stein R, Brindise J. Platelet Activation in Patients Supported by Continuous Flow Left Ventricular Assist Devices. ISHLT 28th Annual Meeting & Scientific Sessions. April 10, 2008. Boston, MA (Accepted for Oral Presentation.)

95. Nutter AL, Slaughter MS, Silver MA. A Decline in the VE/VCO2 Slope from Anaerobic Threshold to

Peak Exercise Predicts Short Term Need for LVAD or Heart Transplant. ISHLT 28th Annual Meeting & Scientific Sessions. April 10, 2008. Boston, MA (Accepted for Oral Presentation.)

96. Khan SN, Feldman CM, Slaughter MS and Silver MA. Preferential Improvement in Exercise Time,

Oxygen Consumption and Ventilatory Response in Patients Supported with Pneumatic versus Electric LVADs. ISHLT 28th Annual Meeting & Scientific Sessions. April 10, 2008. Boston, MA (Accepted for Poster Presentation.)

97. Khan SN, Feldman CM, Slaughter MS and Silver MA. Differential slopes of VE/VC02 at Anaerobic Threshold and Peak Exercise: A Possible Indicator of Myocardial Recovery with LVAD Support. ISHLT 28th Annual Meeting & Scientific Sessions. April 10, 2008. Boston, MA (Accepted for Poster Presentation.)

98. Khan SN, Horrell TJ, Graham JD, Sobieski MA, Silver M and Slaughter MS. Hemocompatibility in Long Term LVAD Support: Continuous vs. Pulsatile Flow. ISHLT 28th Annual Meeting & Scientific Sessions. April 10, 2008. Boston, MA (Accepted for Poster Presentations

99. Boyle AJ, Russell SD, Teuteberg JJ, Moazami N, Moore SA, Slaughter M, Farrar DJ, John R. Low Thromboembolism and Pump Thrombosis Potential of the HeartMate II (HM) LVAD. AHA Scientific Sessions 2007. November 6, 2007. Orlando, FL.

100. Cloe J, Gelijins A, Moskowitz A, Naka Y, Goldstein D, Icenogle T, Slaughter M, Pagani F, Dembitsky W, Rawiel U, Hong K, Parides M, Ascheim D, Schmidt AM. The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation or Implantation of Ventricular Assist Devices. Gordon Research Conference. August 19, 2007. Big Sky, MT.

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101. Slaughter MS, Feldman CM, Silver MA, Sobieski MA, Pappas P and Tatooles A. Low Incidence of Neurologic Events During Long-Term Support with HeartMate XVE. ASAIO 53rd Annual Conference. June 9, 2007. Chicago, IL.

102. Feldman CM, Silver MA, Slaughter MS, Sobieski M and Lonergan-Thomas H. Improvement in

Early Oxygen Uptake Kinetics: A Possible Indicator of a Myocardial Recovery with LVAD Support. ASAIO 53rd Annual Conference. June 9, 2007. Chicago, IL.

103. Slaughter M, Sobieski M, Silver M, Pappas P, Tatooles A. Effect of HeartMate II and

Continuous Flow on the Fibrinolytic System. ASAIO 53rd Annual Conference. June 7, 2007. Chicago, IL.

104. Coyle LA, Martin M, Feldman C, Kurien S, Silver MA and Slaughter MS. Destination Therapy:

Results of National and International Travel ASAIO 53rd Annual Conference. June 7, 2007. Chicago, IL.

105. Koenig SC, Giridharan GA, Ionan C, Pantalos GM, Dowling RD, Prabhu S, Sobieski MA,

Slaughter MS. Comparative Studies Between Human, Bovine, and Porcine Systemic Vascular Input Impedances. ASAIO 53rd Annual Conference. June 7, 2007. Chicago, IL.

106. Koenig SC, Giridharan GA, Ionan C, Pantalos GM, Dowling RD, Prabhu S, Sobieski MA,

Slaughter MS. Systemic Vascular Input Impedance in Humans, Calves, and Pigs: Clinical Implications with Medical Devices and Xenotransplantation. ISHLT 27th Annual Meeting and Scientific Sessions. April 25-28, 2007. San Francisco, CA (Poster Presentation)

107. Slaughter MS, Sobieski MA, Pantalos GM, Giridharan GA, Dowling RD, Prabhu S, Farrar DJ,

Koenig SC. Left Ventricular Pressure Unloading with Continuous and Pulsatile Left Ventricular Assist Devices in Advanced Heart Failure Patients. ISHLT 27th Annual Meeting and Scientific Sessions. April 25-28, 2007. San Francisco, CA (Poster Presentation).

108. Slaughter MS, Sobieski MA, Gallagher C, Dia M, Silver MA. Long-Term Support with

Continuous Flow LVAD’s: Effect of Reduced Pulsatility on Renal Function. ISHLT 27th Annual Meeting and Scientific Sessions. April 25, 2007. San Francisco, CA (Poster Presentation).

109. Lietz K, Long J, Kfoury A, Slaughter M, Silver M, Milano C, Rogers J, Naka Y, Mancini D, Miller

LW. Center Experience and Outcomes of Left-Ventricular Assist Device Implantation as Destination Therapy (DT) – Analysis of Thoratec DT Registry 1998-2005. ACC - American College Cardiology. March 26, 2007. New Orleans, LA.

110. Slaughter MS, Sobieski II MA, Pappas PS, Tatooles AJ. Emergency Insertion of HeartMate XVE

for Persistent Cardiogenic Shock After Acute Myocardial Infarction. ASAIO. June 8, 2006. Chicago, IL.

111. Koenig SC, Dowling RD, Slaughter MS, Sobieski II MA, Giridharan GA, Pantalos GM. Vascular

Pulsatility in Clinical Patients with a Continuous or Pulsatile VAD. ASAIO. June 8, 2006. Chicago, IL.

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112. Slaughter MS, Pederson B, Tatooles AJ, Sobieski II MA. Hydrophone Monitoring: A Novel Method for Non-Invasive Assessment of LVAD Device Failure. ASAIO. June 8, 2006. Chicago, IL.

113. Leitz K, Long J, Kfoury AG, Slaughter MS, Silver MA, Milano CA, Rogers J, Miller LW. The Impact

of Patient Selection on Long-Term Outcomes of Left Ventricular Assist Device Implantation as Destination Therapy for End-Stage Heart Failure. International Society of Heart & Lung Transplantation. April, 2006. Madrid, Spain.

114. Leitz K, Long J, Slaughter MS, Miller L. Preoperative Risk Factors for Early Mortality Following

Use of Left Ventricular Assist Devices as Destination Therapy for End-Stage Heart Failure.American Heart Association. Dallas, TX. November, 2005.

115. Agadi SG, Lonergan-Thomas H, Brennan S, Cianci P, Slaughter MS, Silver MA. Impact of Left

Ventricular Assist Device Destination Therapy on Ventricular Re-Synchronization. Chest 2005 (Poster).

116. Sobieski MA, Kwok WA, Pappas PS, Tatooles AJ, Slaughter MS. Reducing the Effects of the

Systemic Inflammatory Response to Cardiopulmonary Bypass: Can Single Dose Steroids Blunt SIRS? American Society of Extracorporeal Technology. New Orleans, LA. March 5, 2005.

117. Long D, Sobieski II MA, Slaughter MS. Utilization of the HeartMate XVE Left Ventricular Assist

System as Destination Therapy in a Patient with Ischemic Cardiomyopathy: A Case Report. American Society of Extracorporeal Technology. New Orleans, LA. March 5, 2005.

118. Sobieski II MA, Hart D, Pappas PS, Tatooles AJ, Slaughter MS. Utilization of ECMO as a Bridge

to Ventricular Assist and Bridge to Successful Transplantation: A Case Report. American Society of Cardiovascular Perfusion, Tampa, FL. January, 2005.

119. Farrar DJ, Kormos RL, Frazier OH, Long J, Stueber, Slaughter MS, Sun B, Hill JD. Right

Ventricular Afterload in Patients with Continuous Flow and Pulsatile Flow LVADs: Implications for Right Heart Function. International Society of Rotary Blood Pumps. Cleveland, Ohio.

120. Slaughter MS. A Webcast Course on: Advanced Surgical and Clinical Management Strategies

for Patients Requiring Univentricular or Biventricular Support with the Thoratec IVAD. Thoratec Corporation. December 7, 2004.

121. Slaughter MS, Sobieski MA, Silver MA, Tatooles AJ, Pappas PS. Epicardial Blood Flow: A

Comparative Evaluation of the Thoratec PVAD and the HeartMate IP Ventricular Assist Devices. ASAIO. 50(2), 130; Mar-Apr 2004. ASAIO. Washington, DC, June 18, 2004.

122. Slaughter MS, Tsui SL, El-Banayosy A, Kormos RL, Icenogle TB, Hill JD. Home Discharge with a

Thoratec VAD using the TLC-II Portable Driver. ASAIO. 50(2), 120; Mar-Apr 2004. ASAIO. Washington, DC. June 18, 2004.

123. Slaughter MS, Tsui S, El-Banayosy A, Kormos RL, Icenogle TB, Hill JD. The Thoratec IVAD: A

New Implantable Ventricular Assist Device. ISHLT. San Francisco, CA. April 21-24, 2004. (Poster).

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124. Sobieski II MA, Slaughter MS, Hart D, Pappas PS, Tatooles AJ. Prospective Study on Prime

Reduction via the Cardioplegia Delivery System and the Effects on Blood Product and Hemoconcentrator Usage Intra-operatively. American Academy of Cardiovascular Perfusion. San Antonio, TX. January 24, 2004.

125. Evans CC, Walker LA, Rundell VL, George TA, Pappas PS, de Tombe P, Slaughter MS.

Mechanical Support Normalizes Cardiac Myofilament Force-ATPase Relationship in Heart Failure. American Heart Association. Orlando, FL. November 9-12, 2003.

126. Tatooles AJ, Pappas PS, Gordon PJ, Slaughter MS. Robotic Mitral Valve Repair: Improved

Results and Patient Satisfaction. 3rd World Congress on Heart Disease- New trends in Research, Diagnosis and Treatment. July 12-15, 2003.

127. Sobieski M, George T, Slaughter MS. Initial Experience using the Thoratec Mobile Computer in

Conjunction with the TLC-II Ventricular Assist Device Driver. ASAIO. Washington, DC. June 19, 2003.

128. Slaughter MS, Sobieski M, Pappas PS, Tatooles AJ. Hemodynamic advantage of limited stroke

volume vs rate reduction. ASAIO. Washington, DC. June 19, 2003. 129. Banbury MK, Kouchoukos NT, Allen KB, Slaughter MS, Berry G, Horvath KA. The Histologic

Characteristics of Captured Particulate Emboli Using the Embol-X Intra-Aortic Filter during Cardiopulmonary Bypass. Outcomes: The Key West Meeting. Key West, FL. May 21-24, 2003.

130. Sobieski II MA, George TA, Slaughter MS. Initial Experience using the Thoratec Mobile

Computer in Conjunction with the TLC-II Ventricular Assist Device Driver. ASAIO, 49(2), 169; Mar-Apr, 2003.

131. Slaughter MS, Sobieski II MA, Pappas PS, Tatooles AJ. Weaning the Thoratec LVAD:

Hemodynamic Advantage of Limited Stroke Volume vs. Rate Reduction. ASAIO, 49(2),168; Mar-Apr, 2003.

132. Silver MA, Slaughter MS, Pappas PS, Tatooles AJ, Szabo S. Long-Term Survival Following Left

Ventricular Assist and Comprehensive Medical Management As Bridge to Recovery Therapy for Advanced Heart Failure. ISHLT, 22(1S): S211, 2003.

133. Tsui S, Slaughter MS, Hill J, Burton N, Korfer R. Initial Human Experience with the Thoratec

IVAD: A Versatile Implantable Uni- or Bi-ventricular Assist Device. 134. Kumar A, Ozinga D, Boarden W, Slaughter MS. O.R. Extubation after DaVinci Robotic Mitral

Valve Repair. Society of Cardiovascular Anesthesiologists. Aspen, CO. March, 2003. (Poster) 135. Sobieski M, Hart D, Pappas PS, Slaughter MS. Cardiopulmonary Bypass Circuit with Modified

Assisted Venous Drainage in Conjunction with Robotic Mitral Valve Repair. AACP. San Diego, CA. February, 2003.

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136. Silver MA, Slaughter MS, Pappas PS, Tatooles AJ, Szabo S. Long-Term Survival Following Left Ventricular Assist and Comprehensive Medical Management as Bridge to Recovery Therapy for Advanced Heart Failure. ISHLT. Vienna, Austria, 22(1S): S211. 2003.

137. Tsui S, Slaughter MS, Hill J, Burton N, Korfer R. Initial Human Experience with the Thoratec

IVAD: A Versatile Implantable Uni- or Bi-ventricular Assist Device. ISHLT. Vienna, Austria, 22(1S): S201. 2003.

138. Sobieski II MA, Hart D, Pappas PS, Slaughter MS. Cardiopulmonary Bypass Circuit with

Modified Assisted Venous Drainage in Conjunction with Robotic Mitral Valve Repair. AACP. San Diego, CA. January, 2003. JAACP; 24: 49.

139. Banbury MK, Kouchoukos NT, Horvath KA, Slaughter MS, Weissan N, Berry G. The Embol-x

Intra-aortic Filter Reduces Morbidity In Cardiac Surgery: A Multi-centered Randomized Trial of 1,289 Patients. STS. San Diego, CA. January, 2003.

140. Pappas PS, Tatooles AJ, Slaughter MS. Da Vinci Robotic Mitral Valve Repair: Outpatient

Procedure? STS. San Diego, CA. January, 2003. 141. Pappas PS, Tatooles AJ, Slaughter MS. Robotic Mitral Valve Repair: Home Discharge Less than

24 Hours Postoperatively. ATS. January, 2003. 142. Slaughter MS, Pappas P, Tatooles AJ. Skinned Myocyte Contractile Function in Patients with LV

Dysfunction: Predictor of Myocardial Recovery. 8th World Congress on Heart Failure- Mechanisms and Management. Washington, DC. July, 2002.

143. Slaughter MS. Skinned Myocyte Contractile Function in Patients with LV Dysfunction:

Predictor of Myocardial Recovery? The Journal of Heart Failure 7(1): 44, July 2002. 144. Evans CC, de Tombe P, George T, Pappas P, Slaughter MS. Force-ATPase Relationship in

Myofilaments from Patients with Heart Failure and Mitral Valve Disease. ISHR. Madison, WI. July, 2002.

145. Slaughter MS, Silver M, Pappas P, Tatooles A. Home Discharge Experience with the Thoratec

LVAD TLC-II Portable Driver. ASAIO. New York, NY. June, 2002. 146. Slaughter MS, Evans C, Pappas P, Tatooles A. Skinned Myocyte Function and ATP Use in

Patients with LV Dysfunction: Predictor of Recovery? ASAIO. New York, NY. June, 2002. 147. Slaughter MS, Pappas P, Silver M, Tatooles A. Neurologic and Bleeding Complications

Associated with Thoratec Ventricular Assist Device. ASAIO. New York, NY. June, 2002. 148. Mussivand T, Harasaki H, Litwak K, Slaughter MS, et al. In Vivo Evaluation of the

Biocompatibility of a Totally Implantable VAD (HeartSaver VAD). ASAIO. New York, NY. June, 2002.

149. Slaughter M, Pappas P, Tatooles A. First U.S. Home Discharge with the Thoratec TLC-II

Portable VAD Driver. Advances in Cardiac Surgery. San Diego, CA. 2001.

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150. Slaughter MS, George T, Sobieski M, Tatooles A, Pappas P. Home Discharge with the Thoratec

TLC-II Portable Driver. 6th Symposium WAITS. Ottawa, CA. Aug. 18, 2001. 151. Slaughter MS, George T, Sobieski M, Tatooles A, Pappas P. Home Discharge with the Thoratec

TLC-II Portable Driver. Cardiovascular Engineering. 152. Slaughter MS, George T, Sobieski M, Silver M. Initial Experience with Outpatient Excursions

Using the Thoratec TLC-II Portable Driver. Cardiovascular Engineering. 153. Slaughter MS, George T, Sobieski M, Silver M. Initial Experience with Outpatient Excursions

Using the Thoratec TLC-II Portable Driver. 6th Symposium WAITS. Ottawa, CA. Aug. 19, 2001. 154. Slaughter MS, Pappas PS, Tatooles AT. Preliminary Experience with a New Synthetic Coronary

Artery Bypass Graft. (ARIA). 4th Annual New Era Cardiac Care. 84, 2001. (Abstract) (ARIA). New Era in Cardiac Care. Laguna Niguel, CA. January, 2001.

155. Akrami BA, Silver MA, Earhart B, Slaughter MS. Improved and sustained early exercise oxygen

kinetics with mitral valve repair and LVAD support accounts for improved functional status. Journal of Cardiac Failure. 6 (3) Suppl. 2: 38, 2000.

156. Silver MA, Cianci P, Longergan-Thomas H, George TA, Szabo S, Slaughter MS. Rapid up-

titration of beta-blocker therapy in patients being supported with a left ventricular assist device. Journal of Cardiac Failure. 6 (3): 39, 2000.

157. Silver MA, Slaughter MS, Pappas PS, Tatooles AJ, Szabo S. Short-term results of left ventricular

assist and comprehensive medical management as bridge to recovery therapy for advanced heart failure. JACC 2000; 35: 229A.

158. Slaughter MS, Silver M, Tatooles A, Pappas P. Early results of planned bridge to recovery using

Thoratec left ventricular assist device in severe idiopathic dilated cardiomyopathy. ASAIO J 46(2): 186. New York, NY. June, 2000.

159. Silver MA, Slaughter MS, Pappas PS, Tatooles AJ, Szabo S. Short-term results of left ventricular

assist and comprehensive medical management as Bridge to recovery therapy for advance heart failure. American College of Cardiology. Dallas, TX. March, 2000.

160. Slaughter MS, Tatooles A, Hodakowski G, Pappas P. The effect of the internal thoracic artery

on intermediate survival in dialysis patients undergoing coronary revascularization. Chest Supplement 1999. (Abstract) American College of Chest Physicians. Chicago, IL. October, 1999. (Poster).

161. Silver M, Lazzara D, Slaughter MS, Szabo S, Pappas P. Thoracic bioimpedence accurately

determines cardiac output in patients with left ventricular assist devices. Journal of Cardiac Failure 5(3): 38, 1999.

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162. Silver M, Slaughter M. Short-term results of left ventricular assist and comprehensive heart failure management as bridge to recovery therapy for advanced heart failure. Heart Failure Summit V. Cleveland, OH. October, 1999.

163. Silver M, Lazzara D, Slaughter M, Szabo S, Pappas P. Thoracic bioimpedence accurately

determines cardiac output in patients with left ventricular assist devices. Heart Failure Society of America. San Francisco, CA. September, 1999.

164. Slaughter MS, Silver M, Hodakowski G, Pappas P. Mitral valve annuloplasty for ischemic mitral

regurgitation and severe ventricular dysfunction. Journal of Cardiac Failure 5(3):35, 1999. 165. Slaughter M, Silver M, Hodakowski G, Pappas P. Mitral valve annuloplasty for ischemic mitral

regurgitation and severe ventricular dysfunction. Heart Failure Society of America. San Francisco, CA. September, 1999.

166. Tatooles A, Pappas P, Guillory J, Faraci P, Hodakowski G, Perelman M, Slaughter MS. Coronary

artery bypass grafting in patients with renal failure on chronic dialysis. Naurice M. Nesset Research Forum Proceedings, Vol 1, 1997.

167. Slaughter MS, Pappas P, Evans D, Tatooles A, Hodakowski G. Operating room extubation in adults requiring coronary artery bypass grafting. Chest Supplement

112(3):1285, 1997. 168. Slaughter M, Pappas P, Evans D, Tatooles A, Hodakowski G. Operating room extubation in

adults requiring coronary artery bypass grafting. American College of Chest Physicians. New Orleans, LA. October, 1997. (Poster).

169. Slaughter MS, Kshettry V, Smith P, Foker J: Internal mammary artery for arterial pressure

monitoring after pediatric surgery. Clinical Digest Series: Pediatrics Digest, 1994.

170. Smith P, Slaughter M, Petty M, Shumway S, Kshettry V, Bolman III RM. Abdominal complications following lung transplantation. ISHLT. Venice, Italy. March, 1994.

171. Slaughter MS, Nielsen K, Bolman III RM. Heparin-coated circuits as treatment for bleeding

while on extracorporeal membrane oxygenation. Pathophysiology and Techniques of Cardiopulmonary Bypass: Cardiothoracic Surgery Symposium. San Diego, CA. February, 1994.

172. Slaughter M, Braulin E, Bolman III RM, Moline E, Shumway S. Pediatric Cardiac

Transplantation: Results of two and five year follow-up. First International Congress on Pediatric Transplantation. Minneapolis, MN. Aug., 1993.

173. Slaughter M, Nielsen K, Bolman III RM. Extracorporeal membrane oxygenation (EMCO) after

lung or heart-lung transplantation. ASAIO. New Orleans, LA. April, 1993. 174. Pearce W, Slaughter M, Salyapongse N, LeMaire S, Yao J, McCarthy W. Aortic diameters as a

function of age, gender and body surface area. Central Surgical Association. Cincinnati, OH. March, 1993.

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175. Slaughter M, Olson M, Lee J, Ward H. A fifteen-year continuous would surveillance study in patients following coronary artery bypass. Society of Thoracic Surgeons. San Antonio, TX. January, 1993. (Poster).

Thoracic Residency Program:

ACGME 2011-Present

Thoracic Residency Program

University of Louisville 40202

Thoracic Residency Program 2011

Re-accreditation

Rewrote PIF for Thoracic Residency 2009

Thoracic Residents

1) Adam Protos, MD 2015-2016

STS Advocacy Scholarship 2016

ACS Leadership and Advocacy Summit

2) Adam Ubert, MD 2014-2016

3) John Chaney, MD 2013-2015

1st Place Winner 2013-2014

JCTSE and TSDA CT Surgery Resident Top Gun Competition

Award

2nd Place AATS Resident Poster Competition 2015

4) James Neel, MD 2012-2014

JCTSE and TSDA CT Surgery Resident Top Gun Competition 2013

VAD/Transplant Super Fellows:

1) Michele Gallo, MD 2016-2017

Padua, Italy

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2) Anna Meyer, MD 2010-2011

Hanover, Germany

Visiting Faculty:

Jennifer Conway

Toronto Sick Kids VAD Management 2012

ISHLT Travel Award 2012

Research Residents:

Dr. Erin Schumer 2013-2016

Hanover, Germany

ISHLT Travel Award

2nd place AATS Resident Poster Competition 2014

WTS Scholarship Program 2015

ISHLT Travel Grant Award

Micah Whited, MD 2016-2017

Matt Black, MD 2015-2016

Paul Linsky, MD 2012-2013

Matt Fox, MD 2009-2010

Medical Students:

Paul Henly

Distinction in Research 2016-2017

Michael Rogers 2015

STS Looking to the Future Scholarship

Distinction in Research

Mickey Ising 2014

AMA Physicians of Tomorrow Award

STSA James W. Brooks Medical Student Scholarship 2014

Daniel Kütting MD

Student from Germany 2013

Carlo Bartoli, MD, PhD student 2009-2011

STSA James W. Brooks Medical Student Scholarship 2011

Master’s Degree in Bioengineering/Mentor:

Mitchell J. Buller, B.S 2013

Master’s Thesis Advisor/Mentor

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Keith Zoeller 2012-2014

Master's Thesis Advisor/Mentor

Mickey Ising 2010-2011

Master’s Thesis Advisor/Mentor

Joel Graham 2009-2010

Master’s Thesis Advisor/Mentor

Bioengineering Co-op Students:

Young Choi 2012-2016

Whitaker International Fellowship Grant Recipient 2016/2017

Tim Horrell 2008

Joel Graham 2008 -2009

Mickey Ising 2010

Summer Research Associates:

Paul Henley 2016

(Medical Student University of Louisville) AATS Student for the day award

Kevin Luftman 2010

(Medical Student University of Louisville)

Sam Schwartz (Northwestern University) 2011

(Bioengineering student Northwestern University)

Community Service:

Metro United Way Volunteer 2011 - present

Leadership/Management Development:

Professional Training: Team Building Workshop, ARISE Executive Coaching

Department of Cardiovascular and Thoracic Surgery Faculty Retreat 2016

Academic Leadership Program: Human Resources Panel: 2015

“Working with HR to Recruit, Retain, & Recognize Faculty and Staff”

CHI Quarterly Senior Leadership Team Meeting 2014

Mark S. Slaughter, M.D. November 15, 2016

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Strategic Thinking, Carnegie Mellon

Denver, Colorado

CHI Medical Director Summit:

August 2013

Leading Change, Influencing Others, and Using Data to Lead Effectively

Denver, Colorado

AAMC Executive Development Seminar for Associate Deans

and Department Chairs

Fulfilling Leadership and Management Roles Tempe, Arizona 2014