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CURRICULUM VITAE JENNY J. YANG, Ph.D. ADRESS Department of Chemistry Georgia State University 50 Decatur Street, NSC 552 PO Box 4098 Atlanta, GA 30302-4098 Tel: 404-651-4620, Fax: 404-651-2751 E-mail: [email protected] http://chemistry.gsu.edu/faculty/Yang/Yang.html EDUCATION 1992 Ph.D. Biochemistry (Distinguished), Florida State University, Tallahassee, FL Graduate Research Advisor: Dr. Harold Van Wart Dissertation Title: Kinetic Studies of the Catalytic Pathway of Thermolysin 1985 M.S. Analytical Chemistry (Honors), Xiangtan University, Xiangtan, Hunan, China Graduate Research Advisor: Professor Shiling Tang Thesis Title: Electro-analysis of Trace Zinc and Copper 1982 B.S. Chemistry with High Honors, Xiangtan University, Xiangtan, Hunan, China Undergraduate Research Advisor: Professor Weikuan Yiao Research Project: Detection and Analysis of Biological Elements PROFESSIONAL CREDENTIALS 2006-Present Georgia State University, Department of Chemistry, Atlanta, GA Professor of Biochemistry and Biophysics 2002-2006 Georgia State University, Department of Chemistry, Atlanta, GA Associate Professor of Biochemistry and Biophysics (Tenured) University of Georgia, Adjunct Professor, Center for Metalloenzyme Studies Centers for Disease Control and Prevention: Guest Researcher Journal of Calcium Binding Protein: Associate Editor Journal of Protein & Peptide Letters (PPL): Editorial Board Member 1997-2001 Georgia State University, Department of Chemistry, Atlanta, GA Assistant Professor of Biochemistry 1 V.1

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Page 1: Curriculum Vitae Jenny 6-20-07

CURRICULUM VITAE

JENNY J. YANG, Ph.D.

ADRESS Department of Chemistry Georgia State University50 Decatur Street, NSC 552PO Box 4098Atlanta, GA 30302-4098Tel: 404-651-4620, Fax: 404-651-2751 E-mail: [email protected]://chemistry.gsu.edu/faculty/Yang/Yang.html

EDUCATION

1992 Ph.D. Biochemistry (Distinguished), Florida State University, Tallahassee, FLGraduate Research Advisor: Dr. Harold Van WartDissertation Title: Kinetic Studies of the Catalytic Pathway of Thermolysin

1985 M.S. Analytical Chemistry (Honors), Xiangtan University, Xiangtan, Hunan, ChinaGraduate Research Advisor: Professor Shiling TangThesis Title: Electro-analysis of Trace Zinc and Copper

1982 B.S. Chemistry with High Honors, Xiangtan University, Xiangtan, Hunan, ChinaUndergraduate Research Advisor: Professor Weikuan YiaoResearch Project: Detection and Analysis of Biological Elements

PROFESSIONAL CREDENTIALS

2006-Present Georgia State University, Department of Chemistry, Atlanta, GAProfessor of Biochemistry and Biophysics

2002-2006 Georgia State University, Department of Chemistry, Atlanta, GAAssociate Professor of Biochemistry and Biophysics (Tenured)University of Georgia, Adjunct Professor, Center for Metalloenzyme StudiesCenters for Disease Control and Prevention: Guest ResearcherJournal of Calcium Binding Protein: Associate EditorJournal of Protein & Peptide Letters (PPL): Editorial Board Member

1997-2001 Georgia State University, Department of Chemistry, Atlanta, GA Assistant Professor of Biochemistry

1995-1997 Yale University, Department of Molecular Biophysics & Biochemistry, New HavenHardford Postdoctoral Research Associate Advisor: Professor Lynne Regan

1993-1995 University of Oxford, Oxford Center for Molecular Sciences (OCMS), UKOCMS Postdoctoral Research Fellow Advisors: Professor Chris M. Dobson (FRS) and Professor Sheena E. Radford

1992-1993 Syntex Discovery Research (Roche Biosciences) Institute of Biochemistry and Cell Biology, Palo Alto, CA

Postdoctoral Research Fellow Advisor: Professor Harold E. Van Wart

1982-1987 Xiangtan University, Department of Chemistry, Hunan, China Faculty of Analytical Chemistry

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AWARDS AND HONORS

2005-present Editorial Board Member of Journal of Protein & Peptide Letters (PPL) 2004-present Associate Editor of Journal of Calcium Binding Protein2007-present Panel Grant Reviewer of the Study Session of Biochemistry and Biophysics of

Membranes Study Section, National Institute of Health 2004-2005 Medical Research Award from NIH, Southeast Research Center for Emerging

Diseases and Biodefense (SERCEB)2005-present Panel Grant Reviewer of the Study Session of SBMI Medical Imaging Technologies,

National Institute of Health (National Cancer Institute)2005-2006 Panel Grant Reviewer of the Study Session of National Institute of Health for

postdoctoral Fellowship of Biophysics and Biochemistry2004 Speaker at the Gordon Conference of Biomineralization2001-2004 Panel Grant Reviewer of National Science Foundation (NSF-MCB)2004 Panel Grant Reviewer of the Study Session of National Institute of Health (SBDD)2003 Honor from McNair Program for outstanding achievement in training minority

undergraduate researchers2002-2005 Panel Grant Reviewer of the Study Session of National Institute of Health for

Predoctoral Fellowship (F31)2003 Outstanding Faculty Achievement Award, Georgia State University 2003 Featuring Recognition for Outstanding Contribution to McNair Minority

Undergraduate Research Program2001 Outstanding Junior Faculty Award, Georgia State University, Arts and Sciences1996 Donahue Foundation Research Award 1995 –1996 Hartford Research Award 1993 –1995 Oxford Center for Molecular Sciences Fellowship 1992 Distinguished Graduate Student at Florida State University 1992 Best Presentation at the Florida American Chemistry Society meeting 1992 Sigma Xi 1986 Outstanding Instruction Award, Xiangtan University1985 Outstanding Graduate Student Award, Xiangtan University1982 Outstanding Undergraduate Student Award, Xiangtan University

PROFESSIONAL AFFILIATIONS

Editorial Board Member of Journal of Protein & Peptide Letters (PPL)Associate Editor of Journal of Calcium Binding ProteinGuest Researcher at Centers for Disease Control and Prevention, Atlanta, GAAdjunct Professor at the Center for Metalloenzyme Studies, University of Georgia, Athens, GABiomolecular Computing Resources (BIMCORE). Emory University, Atlanta, GACenter for Drug Design and Advanced Biotechnology, Georgia State University, Atlanta, GA Program of Brains and Behavior Neuron ScienceProgram of Molecular Bases of Diseases at GSUEuropean Calcium SocietyThe Royal Society of Chemistry The American Chemical SocietyThe American Peptide SocietyThe Biophysical SocietyThe Chinese Americans in Academia Society

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The Atlanta Calcium Club (Organizer)

CURRENT ACTIVE EXTERNAL SUPPORT

1. Title: Design of Protein-Based MRI Contrast Agents with High Relaxivity Source: National Institutes of Health/NIBIB 1R01EB007268-01Period: 07/01/07- 6/30/12PI: Dr. Jenny J. YangCo-PI: Dr. Zhi-ren LiuCollaborators: Drs. Xiaoping Hu, Eirik Krogstad and Delon BarfussDirect costs: $1,250,000 (percentile 1.3)2. Title: Structural Biology of receptor-mediated extracellular calcium signalingSource: NIH/GM 1R01GM081749-01Co-PI: Dr. Ed. Brown (The Brigham and Women’s Hospital, Harvard University)Period: 07/01/07 - 06/30/12 Direct costs: $1,250,000

3. Title: Rational Design and Analysis of Calcium Binding ProteinsSource: National Institute of Health/GM 1RO1GM62999-01PI: Dr. Jenny J. YangPeriod: 07/01/01 – 06/30/08Direct costs: $1,272,5004. Title: Identification of Calcium-Binding Sites in Calcium-sensing ReceptorsSource: American Heart AssociationPI: Dr. Jenny J. YangPeriod: 07/01/06 - 06/30/08 Award: $154,000

5. Title: Molecular Imaging of CancersSource: ELSA U Pardee FoundationPeriod: 06/01/06– 05/31/08PI: Dr. Jenny J YangDirect costs: $75,000

6. Title: Regulation of Lens Gap JunctionsSource: National Institute of Health/Eye Institute 5R01AI021389PI: Dr. Charles LouisCo-PI: Dr. Jenny J. YangPeriod: 09/01/04- 08/31/08Direct costs: $1,250,000

7. Title: Molecular Biology of Rubella VirusSource: NIH/NIAID 5R01AI021389Period: 04/01/03 - 03/31/08PI: Dr. Teryl K. Frey Co-PI: Dr. Jenny J. YangDirect costs: $1,150,000

8. Title: Functional role of p68 tyrosine phosphorylation in cancer metastasisSource: National Institutes of Health/NCIPeriod: 07/01/07- 06/30/12

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PI: Dr. Zhi-ren LiuCo-PI: Dr. Jenny J. Yang

Direct costs: $1,000,000 (percentile 1.7)

9. Title: Molecular MR Imaging by Targeting Cancer Biomarkers Source: National Institutes of Health/NCI 1R21CA120181-01A1Period: 05/01/07- 04/30/09PI: Dr. Zhi-ren LiuCo-PI: Dr. Jenny J. YangDirect costs: $275,000 (percentile 9.6, priority score 139)

10. Title: Supplemental Award for Minority Undergraduate Student ResearchSource: National Institute of Health/GMPI: Dr. Jenny J. YangPeriod: 03/01/04 – 06/30/08Total costs: $114,385

CURRENT INTERNAL SUPPORT

1. Title: Analysis of Neuro-Muscular Control of Locomotion of the Nematode Caenorhabditis Elegans

Source: GSU Brain and Behavior Research Program Period: 01/01/07– 12/31/07PI: Dr. Gennady CymbalyukCo-PI: Drs. Walter Bill Walthall and Jenny J. YangDirect costs: $29, 743

2. Title: Monitoring Calcium Signaling in Brains and NeuronsSource: GSU Research Program Period: 07/01/05– 12/31/07PI: Dr. Jenny J YangCo-PI: Vincent Rehder Direct costs: $20,000

3. Title: Brains and BehaviorAwarder: Ms. Nancy Yun Huang (Pre-doctoral Fellowship)Period: 1/1/07-2/30/2010Stipend: $22,500/year

4. Title: Molecular Bases of DiseasesAwarder: Mr. Ning Chen (Pre-doctoral Fellowship)Period: 5/1/07-4/30/10Stipend: $22,500/yr

5. Title: Molecular Bases of DiseasesAwarder: Mr. Yubin Zhou (Pre-doctoral Fellowship)Period: 151/06-4/30/08Stipend: $22,500/yr

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PROPOSALS PENDING

1. Title: Molecular Biology of Rubella VirusSource: NIH/NIAID 11R01AI021389Period: 04/01/07 - 03/31/12PI: Dr. Teryl K. Frey Co-PI: Dr. Jenny J. YangDirect costs: $1,150,000

2. Title: Developing Calcium Sensors to Monitor Calcium Signaling in Cardiac CellsSource: NIH/GM/HL, K01PI: Dr. Jin Zou (Yang sponsor)Period: 07/01/07 - 06/30/09 Award: $375,0003. Title: Developing Calcium Sensors to Monitor Calcium Signaling in Heart DiseasesSource: American Heart Association/research initiation grantPI: Dr. Jin Zou (Yang sponsor)Period: 07/01/08 - 06/30/10 Award: $150,000

PROPOSALS FUNDED SINCE 1997

EXTERNAL

1. Title: Design of Calcium Sensors to Monitor Calcium Signaling in ER Source: National Institutes of Health/GM 1R21GM070555-01Period: 06/01/04 - 5/31/07PI: Dr. Jenny J. YangCo-PI: Dr. Charles LouisDirect costs: $363,7502. Title: Key Determinants of Calcium-Binding Affinity of EF-hand ProteinsSource: National Science Foundation MCB0092486PI: Dr. Jenny J. YangPeriod: 04/01/01 - 03/31/05 Award: $300,0003. Title: Molecular Recognition of the TNF Receptor Encoded by Variola Virus Source: The Southeastern Center for Emerging Biological ThreatsPeriod: 9/1/03– 8/31/05PI: Dr. Jenny J. YangDirect costs: $50,000

4. Title: Supplemental Award for Undergraduate ResearchSource: National Science FoundationPI: Dr. Jenny J. YangPeriod: 04/01/01 - 05/31/05Total costs: $7,500

5. Title: Conformational Change of EF-hand Proteins by GraftingSource: NSF for Minority Graduate Student

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Period: 10/01/02 - 3/30/05PI: Dr. Jenny J. Yang Direct costs: $33,000

6. Title: Supplemental Award for Minority Graduate Student ResearchSource: National Institute of HealthPI: Dr. Jenny J. YangPeriod: 07/01/01 – 06/30/06Total costs: $37,500

7. Title: NIH Pre-doctoral Fellowship for Graduate Research (Sponsor)

Source: National Institute of HealthPI: Ms. Anna WilkinsPeriod: 01/01/03-09/30/05Direct costs: $72,000

8. Title: AHA Pre-doctoral Fellowship for Graduate Research (Sponsor)

Source: American Heart AssociationPI: Ms. April EllisPeriod: 07/01/03-06/30/05Direct costs: $36,000

9. Title: Mass Spectrometry Instruments at Atlanta Source: National Institutes of HealthPeriod: 07/01/02-06/30/03PI: James Power (The Georgia Institute of Technology) Direct costs: $400,000

10. Title: Southeast Collaboratory for High-Field Biomolecular NMR (900 MHz)Source: National Institutes of HealthPeriod: 07/01/02-06/30/07PI: James Prestegard (The University of Georgia)Direct costs: $5,045,000

11. Title: NSF-Atlanta Undergraduate Research Alliance (Sponsor)Source: AURAPeriod: 09/01/04-06/30/05PI: Alice Luo (Georgia Institute of Technology)Direct costs: $2500

12. Title: Developing Protein-Based Sensor for Diagnosing PoxvirusesSource: NIH, Southeast Research Center for Emerging Diseases and Biodefense

(SERCEB) PI: Dr. Jenny J. YangPeriod: 01/01/05- 12/31/05Direct costs: $50,000

13. Title: GANN Minority Pre-doctoral Fellowship for Graduate Research (Sponsor)

Source: Grants in Areas of National Need (GANN)Awarder: Ms. Lisa Jones (PI: Davon Kennedy)

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Period: 07/01/04-08/30/06

14. Title: Predicting Calcium Binding Sites with Graphing Theory AlgorithmSource: GSU/National Institutes of Health P20Period: 1/01/04 -12/31/06 PI: Guantao ChenCo-PI: Jenny J. YangDirect costs: $20,000

INTERNAL

1. Title: Rapid Folding of ProteinsSource: GSU-Quality Improvement FundPeriod: 07/01/97 – 06/30/98PI: Dr. Jenny J. YangTotal costs: $18,908

2. Title: Design of Calcium Binding ProteinsSource: GSU-Research Initiation GrantPeriod: 07/01/97 – 06/30/98PI: Dr. Jenny J. YangTotal costs: $5,000

3. Title: Engineering of Calcium Binding ProteinsSource: GSU-Mentoring GrantPeriod: 07/01/98 – 06/30/99PI: Dr. Jenny J. YangCO-PI: Dr. Dabney DixonTotal costs: $12,000

4. Title: Calcium Dependent TriggersSource: GSU-Research Initiation GrantPeriod: 07/01/99 – 06/30/00PI: Dr. Jenny J. YangTotal costs: $7,000

5. Title: Structural and Functional Analysis of Rubella Virus Nonstructural ProteaseSource: GSU-Team Grant Period: 07/01/00 – 06/30/2001PI: Dr. Jenny J. YangCo-PI: Dr. Teryl K. FreyTotal costs: $17,000

6. Title: Molecular RecognitionSource: GSU Research Program EnhancementPeriod: 07/01/98– 06/30/00PI: Dr. David WilsonCo-PI: Allison, Dixon, and YangDirect costs: $85,000

7. Title: Biophysical Investigation of BiomoleculesSource: GSU-Quality Improvement FundPeriod: 07/01/01– 06/30/02PI: Dr. Giovanni Gadda

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Co-PI: Breyer, Dixon, Wilson, and YangDirect costs: $25,000

8-12. Title: Drug Design and SynthesisSource: GSU Research Program EnhancementPeriod: 07/01/00– 06/30/06PI: Dr. Lucjan StrekowskiCo-PI: Baumstark, Grant, Kennedy and YangDirect costs: 6x $80,000

13. Title: Upgrading Fluorescent spectrometerSource: GSUPeriod: 07/01/04– 06/30/05PI: Dr. Markus GermannCo-PI: Netzel, Wilson, and YangDirect costs: $25,000

14. Title: Monitoring Calcium Signaling in Brains and NeuronsSource: GSU Research Program Period: 07/01/04– 06/30/06PI: Dr. Jenny J YangCo-PI: Vincent Rehder Direct costs: $30,000

GEORGIA STATE UNIVERSITY SERVICE

Chemistry Executive Committee 2006- presentChemistry M.S. Curriculum Committee Fall 1999Chemistry Curriculum Committee 2004 - 2006Chemistry Atlanta NMR Facility Committee 1997- presentChemistry M.S. Graduate Admission Committee ~90 Spring 1999- 2003Chemistry B.S. Honors and Awards Committee ~60 Spring 1999- presentChemistry Ph.D. Dissertation Committees 12 1997- presentChemistry Ph.D. Qualifying Examination Committee 30 1997- presentChemistry Faculty Search Committee 2003- presentChemistry Chair of the Biochemistry Ph.D. Qualifying Examination CommitteeChemistry Seminar Speaker invited > 70 GSU Asian American Studies Research Center Committee 2002- presentGSU Internal Grants Review Committee 2001- presentGSU University Biosafty Committee 2001- present GSU University Senate Committee 2007- present

. EDITORIAL/REVIEWER PROJECTS

Associate Editor of Journal of Calcium Binding Protein (2004-present) Editorial Board Member of Journal of Protein & Peptide Letters (PPL) (2005-present) Reviewer of Grant Proposals:

National Institute of Health/ National Cancer Institute (Study Session of STTR/SBIR, 2005-present)National Institute of Health (Study Session of Biophysics-Postdoctoral Fellowship, 2005-06)National Science Foundation (Panel of MCB, 2001-2004)

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National Institute of Health (Study Session for Predoctoral Fellowship 2002-present)National Science Foundation (Ad Hoc Instrumentation)Research Cooperation (Ad Hoc)Hong Kong Research Grants Council (Ad Hoc)The Welcome Trust-International Research fellowship UK (Ad Hoc)Israel Science Foundation (ISF) (Ad Hoc)Department of Defense

Ad Hoc Reviewer of Scientific Articles:

Proceeding of National Academic Proceedings

Journal of the American Chemical Society

Journal of Biological Chemistry

Biochemistry

Protein Science

BBABiological Inorganic ChemistryFEBS Letter Current Opinions for Structural BiologyTalantaBiomacromoleculesArchives of Biochemistry and BiophysicsProtein EngineeringJournal of Inorganic BiochemistryJournal of BacteriologyJournal of Biological Inorganic ChemistryBioorganic & Medicinal ChemistryBiotechnology & BioengineeringJournal of Physical Chemistry

Grant Review Consultant for the MORE Program at California State University Lectured at the NSF-sponsored Workshop of Molecular Genetics and Protein Engineering

2001, 2002

Wrote sections in proposal to obtain Mass spectrometry instruments for Georgia State University and Georgia Institute of Technology from National Institute of Health (Direct costs: $400,000)

Wrote sections in proposal to obtain high-field biomolecular NMR (900 MHz) for Southeast Collaboratory from National Institute of Health (Direct costs: $5,045,000.00)

Wrote sections in proposal to support Biocontainment Laboratory at GSU from National Institute of Health, 2004

Section Chair “Calcium Signaling” Section at American Chemistry Society Southeastern Regional Meeting, GA, November, 2003.

Organizing Calcium Club at Southeast Region Organizing and Chairing Atlanta Calcium Signaling Symposium 2005 Section chair of Metalloprotein and Protein Design ConferenceChicago, IL, July 28-30,

2005. Section Chair of Symposium of Southeast NMR, Atlanta, GA, November 12, 2005.

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PUBLICATIONS

(51). Shunyi Li, Wei Yang, Anna Wilkins Mannicia, Doyle Barrow Jr., and Jenny Yang, Rational Design of Switchable Calcium and Lanthanide Binding Proteins. Journal of the American Chemical Society Revision (2007).

(50) Yubin Zhou, Wei Yang, Hsiau-Wei Lee, Yiming Ye, Yumei Zhou, Suganthi Suppiah, Teryl K. Frey and Jenny J. Yang. Probing the Ca2+-Binding Properties of the Rubella Virus Nonstructural Protease. Journal of Virology In Press (2007).

(49).Jenny J. Yang, Jianhua Yang, Lixia Wei, Wei Yang, Omar Zurkiya, Hui Mao, Fuqian Zhao, Russell Malchow, Shunyi Li, Anna L. Wilkins Mannicia, Shumin Zhao, Jin Zou, Julian Johnson, Xiaoping Hu, Eirk Krogstad, and Zhi-Ren Liu, Rational Design Protein Based MRI Contrast Agents with High Relaxivity Nature Biotechnology Revision (2007).

(48). Yun Huang, Yubin Zhou, Wei Yang, Robert Butters, Hsiau-wei Lee, Shunyi Li, Andriana Castiblanco, Edward Brown, and Jenny J. Yang. Identification and dissection of Ca2+-binding sites in the extracellular domain of Ca2+-sensing receptor. Journal of Biological Chemistry (2007). May 3; [Epub ahead of print]

(47) Yanling Zhang, Minyong Li, Sekar Chandrasekaran, Xingming Gao, Xikui Fang, Hsiau-wei Lee, Kenneth Hardcastle, Jenny Yang, and Binghe Wang. The first boronic acid supramolecular structure that relies on double intermolecular B-N bonds for self-assembly in solid state and in solution. Tetrahedron (2007).

(46) Jin Zou, Aldebaran M. Hofer, Monica Lurtz, Giovanni Gadda, April L. Ellis, Ning Chen, Yun Huang, Angela Holder, Yiming Ye, Charles Louis, Kristy Welshhans, Vincent Rehder, and Jenny J. Yang. Developing Sensors for Real Time Imaging of High Calcium Concentrations. Biochemistry Revision (2007).

(45) Lisa Jones, Wei Yang, Anna L. Wilkins Mannicia, Alice Kearney, Anton P. van der Merwe, and Jenny J. Yang. Rational Design of a novel calcium binding site adjacent to the ligand binding site on CD2 increases its adhesion function. Protein Design and Engineering In Press (2007).

(44). Jenny J. Yang, Roland Pochet, and Arthur S. Nolen. Calcium, diversity and evolution, Meeting report of calcium binding proteins in normal and transformed cells and Diseases, Calcium Binding Protein (2006) 1(3), 170-174.

(43). Yuan Liu, Qiao Tong, Yubin Zhou, Hsiau-Wei Lee, Jenny J. Yang, Hans-Jörg Bühring, Yi-Tien Chen, Binh Ha, Celia X.-J. Chen and Ke Zen. Functional Elements on SIRPα IgV Domain Mediate Cell Surface Binding to CD47 Journal of Molecular Biology (2006) 365(3):680-93. Epub 2006 Oct 3.

(42) Jenny J. Yang. Calmodulin, the Surprises Continue. Calcium Binding Protein (2006), 1 (2), 65-66.

(41). Yubin Zhou, Michael Kirberger, Hsiau-Wei Lee, Gayatri Ayalasomayajula, Wei Yang, and Jenny J.Yang. Prediction of EF-hand calcium binding proteins and Analysis of Bacterial EF-Hand Proteins. Proteins: Structure, Function, and Bioinformatics (2006), 65(3):643-55.

(40) Anna Wilkins Maniccia, Wei Yang, Shun-yi Li, Julian A. Johnson and Jenny J. Yang. Using Protein Design to Dissect the Effect of Charge Residues on Metal Binding and Protein Stability. Biochemistry, (2006) 45(18):5848-56.

(39) Hai Deng, GT Chen, Wei Yang and Jenny J. Yang. Identifying and Predicting Calcium Binding Sites in Proteins using Graph and Geometry Algorithms. Proteins (2006), 64(1):34-42.Apr 14; [Epub ahead of print].

(38). Chunru Lin, Liuqing Yang, Jenny J. Yang, Youliang Huang, and Zhi-Ren Liu, ATPase/Helicase Activities of p68 RNA Helicase are Required for Pre-mRNA

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Splicing but not for Assembly of the Spliceosome. Molecular and Cellular Biology (2005). 25 (17) 7484-7493.

(37) Wei Yang, Anna Wilkins, Shunyi Li, Yiming Ye, and Jenny J Yang. The Effects of Ca2+ Binding on the Dynamic Properties of a Designed Ca2+-binding Protein. Biochemistry (2005), 44, 8267-8273.

(36) Jin Zou, Yiming Ye, Kristy Welshhans, Monica Lurtz, April Ellis, Charles Louis, Vincent Rehder and Jenny J. Yang. Expression and Optical Properties of Green Fluorescent Protein Expressed in Different Cellular Environments. Journal of Biotechnology (2005). 119(4):368-78.

(35) Yiming Ye, Hsiau-Wei Lee, Wei Yang, and Jenny J. Yang. Calcium and Lanthanide Affinity of the EF-loops from the C-terminal of Calmodulin. Journal of Inorganic Biochemistry (2005), 99, 1376-1383.

(34) Amy R. Carroll, Wei Yang, Yiming Ye, and Jenny Jie Yang. Amyloid Fibril Formation in a Domain of Rat Cell Adhesion Molecule. Cell Biochemistry and Biophysics (2006), 44(2):241-50.

(33) Yiming Ye, Hsiau-Wei Lee, Wei Yang, Sarah Shealy, and Jenny J. Yang. Probing site-specific metal binding affinity of EF-hand Proteins by Grafting. Journal of the American Chemical Society (2005), 127 (11), 3743-50.

(32) Wei Yang, Anna Wilkins, Yiming Ye, Zhi-ren Liu, Shunyi Li, Jeffrey L. Urbauer, Homme W. Hellinga, Alice Kearney, Anton P. van der Merwe and Jenny J. Yang. Design of a Calcium-Binding Protein with Desired Structure in a Cell Adhesion Molecule. Journal of the American Chemical Society (2005), 127 (7), 2085-2093.

(31) Liuqing Yang, Jenny Yang, Youliang Huang, and Zhi-Ren Liu, Phosphorylation of p68 RNA helicase regulates RNA binding by the C-terminal domain of the protein. BBRC (2004), 314(2), 622-630.

(30) Wei Yang, Lisa Jones, Leanne Isley, Yiming Ye, Hsiau-Wei Lee, Anna Wilkins, Zhi-ren Liu, Homme W. Hellinga, Russell Malchow, Mohammed Ghazi and Jenny J. Yang. Rational Design of a Calcium Binding Protein. Journal of the American Chemical Society, (2003), 125(20), 6165-71.

(29) Anna Wilkins, Wei Yang, and Jenny J. Yang, Structural Biology of the Cell Adhesion Protein CD2: From Molecular Recognition to Protein Folding and Design. Current Protein and Peptide Science (2003), 4, 367-73.

(28) Jenny J. Yang and Wei Yang, Calcium Binding Proteins Encyclopedia of Inorganic Chemistry, Bruce King (Eds.) 2nd Edition, John Wiley & Sons, Ltd (2005).

(27) Yiming Ye, Sarah J. Shealy, Hsiau-Wei Lee, Ivan Torshin, Robert Harrison, and Jenny J. Yang “A Grafting Approach for Site-Specific Metal Binding Affinity of EF-hand Proteins.” Protein Engineering (2003), 16(6), 429-34.

(26) Jenny J. Yang, Amy Gawthrop, and Yiming Ye “Obtaining Site-specific Calcium –binding Affinities of Calmodulin” Protein and Peptide Letter (2003), 10 (4), 331-345.

(25) Hsiau-wei Lee, Wei Yang, Yiming Ye, Zhi-ren Liu, John Glushka and Jenny J. Yang, Isolated EF-loop III of Calmodulin in a Scaffold Protein Remains Unpaired in Solution Using Pulsed-field-gradient NMR Spectroscopy. BBA (2002), 1598, 80-87.

(24) Anna L. Wilkins, Yiming Ye, Wei Yang, Zhi-ren Liu, Sarah Shealy, Hsiau-wei Lee, and Jenny J. Yang. Metal-binding Studies for a de novo Designed Calcium-binding Protein. Protein Engineering (2002), 15(7), 571-574.

(23) April L. Ellis, J. Christian Mason, Hsiau-wei Lee, Lucjan Strekowski, Gabor Patonay, Hoseob Choi, Jenny J. Yang. Design, Synthesis, and Characterization of a Calcium-Sensitive Near Infrared Dye. Talanta (2002), 56, 1099-1107.

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(22) Wei Yang, Hsiau-wei Lee, Homme Hellinga and Jenny J. Yang. Structural Analysis, Identification, and Design of Calcium-Binding Sites in Proteins. Proteins (2002), 47, 344-356.

(21) Jenny J. Yang, Haidong Yang, Yiming Ye, Harry Hopkins & Gary Hastings. Temperature-Induced Formation of a Non-native Intermediate State of the all Beta-sheet Protein CD2. Cell Biochemistry and Biophysics (2002), 36, 1-18.

(20) Yiming Ye, Hsiau-Wei Lee, Wei Yang, Sarah J. Shealy, Anna L. Wilkins, Zhi-ren Liu, Ivan Torshin, Robert Harrison, Robert Wohlhueter and Jenny J. Yang. Metal Binding Affinity and Structural Properties of an Isolated EF-loop in a Scaffold Protein. Protein Engineering (2001), 14(12), 1001-1013.

(19) Jenny J. Yang, Yiming Ye, Amy Carroll, Wei Yang, and Hsiau-wei Lee. Structural Biology of the Cell Adhesion Protein CD2: Alternatively Folded States and Structure-function Relation. Current Protein and Peptide Science (2001), 2 (1), 1-17.

(18) Jenny J. Yang, Amy R. Carroll, Wei Yang, Yiming Ye, and, Christina Nguyen. Nonnative Intermediate State of Acid-Stable -Sheet Protein. Cell Biochemistry and Biophysics (2000) 33, 253-273.

(17) Wei Yang, Hsiau-wei Lee, Homme Hellinga, Michelle Pu and Jenny J. Yang. Identifying and Designing Calcium Binding Sites in Proteins by Computational Algorithm. Computational Studies, Nanotechnology, and Solution Thermodynamics of Polymer Systems. Kluwer Academic/Plenum Publishers. 127-138, 2000.

(16) Wei Yang, Hsiau-wei Lee, Zhi-ren Liu, Homme Hellinga and Jenny J. Yang. Criteria for Designing a Calcium Binding Protein. Peptides: The Wave of the Future, R. A. Houghten & M. Lebl. (Eds.), Escom Leiden (2001), 811-813.

(15) Yiming Ye, Annie Lin and Jenny J. Yang. Calcium Binding Properties of EF-loops in a Beta-sheet Protein. Peptides: The Wave of the Future, R. A. Houghten & M. Lebl. (Eds.), Escom Leiden (2001), 450-451.

(14) Wei Yang, Tom Tsai, Mark Kats, & Jenny Jie Yang. Peptide Analogs from E-Cadherin with Different Calcium Binding Affinity. Journal of Peptide Research (2000) 55, 203-215.

(13) Xin Liu, Jenny J. Yang, Mohamad Ghazi & Teryl Frey. Characterization of the Zinc Binding Activity of the Rubella Virus Nonstructural Protease. Journal of Virology (2000) 74, 5949-5956.

(12) Wei Yang. Yiming Ye and Jenny Jie Yang. A Sensitive Method for Selecting Calcium-binding Proteins. Luminescene Forum, (1999) 5, 4-8.

(11) Wei Yang and Jenny Jie Yang Investigation of Conformational Properties of Ca(II)-binding Peptides in Cell Adhesion Molecules. Peptides: Frontiers of Peptide Science, J. Tam & Kaumaya, P.T.P, R.S. (Eds.), Escom Leiden (1997),112-113.

(10) Jenny Jie Yang, van den Berg, B., Pitkeathly, M., Smith, L., Bolin, K.A., Keiderling, T., Redfield, C., Dobson, C. M., & Radford, S.E. Native-like Secondary Structure in a Peptide from the alpha-domain of Hen Lysozyme. Structure, Folding & Design (1996) 25, 473-484.

(9) Jenny Jie Yang, Matthias Buck, Maureen Pitkeathly, Michael Kotik, Donald T. Haynie, Christopher M. Dobson, and Sheena E. Radford. Conformational Properties of Four Peptides Spanning the Entire Sequence of Hen Lysozyme. Journal of Molecular Biology (1995) 252, 483-491.

(8) Mary Gregoriou, Pam F. Jones, John F. Timms, Jenny J. Yang, Sheena E. Radford and Anthony R. Rees. Physicochemical Characterization of the Cytoplasmic Domain of the EGF Receptor and Evidence for Conformational Changes Associated with its Activation by Ammonium Sulfate. Biochemistry Journal (1995) 305, 667-678.

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(7) Jenny Jie Yang and Harold E. Van Wart. Kinetics of Hydrolysis of Dansyl-Peptide by Thermolysin: Analysis of Fluorescence Change and Determination of Steady-State Kinetic Parameters. Biochemistry (1994), 33, 6508-6515.

(6) Jenny Jie Yang, Dean R. Artis, and Harold E. Van Wart. Differential Effect of Halide Anions on the Hydrolysis of Different Dansyl-Substrates by Thermolysin. Biochemistry (1994), 33, 6516-6523.

(5) Jenny Jie Yang, Maureen Pitkeathly, and Sheena E. Radford. Far UV Circular Dichroism Reveals a Conformation Switch in a Peptide Fragment from the Beta- Sheet of Hen Lysozyme. Biochemistry (1994) 33, 7345-7353.

(4) Jenny Jie Yang, Maureen Pitkeathly, Christina Redfield, Christopher M. Dobson and Sheena E. Radford. Using Peptide Models to Dissect the Protein Folding Pathway. Peptides: Chemistry, Structure and Biology, Kaumaya, P.T.P. and Hodges, R.S. (Eds.), Escom Leiden (1995) 825-826.

(3) Jenny Jie Yang, Maureen Pitkeathly, Christina Redfield, Christopher M. Dobson and Sheena E. Radford. Tracing Protein Folding Pathway by Using Peptide Models. Perspectives on Protein Engineering 60-61 (1994).

(2) Jenny Jie Yang, Maureen Pitkeathly, and Sheena E. Radford. Investigation of the Folding of beta-sheet Peptide Fragment of Lysozyme by Circular Dichroism and Size Exclusion Chromatography. Proceedings of 5th International Conference on Circular Dichroism 80-84 (1993).

(1) Jie Yang and Shi-lin Tan. Determination of Trace Elements by Anodic Stripping Voltammetry. Journal of Xiangtan Science (1986) 4, 64-70.

SUBMITTED

(1) Sarah J. Shealy, Yiming Ye, Wei Yang, and Jenny J. Yang. Correlating Protein Rigidity with Thrombin Cleavage by Mass Spectroscopy. Revised to BBA (2007).

(2) Youliang Huang, Liuqing Yang, Jenny J. Yang, and Zhi-Ren Liu, Activities of the Nuclear p68 RNA Helicase are Affected by Sequence Motifs Inside and Outside of the Helicase-core. Submitted to Journal Biological Chemistry (2007).

(3). April Ellis, Wei Yang, Yiming Ye, and Jenny J. Yang. Design calcium-binding Green Fluorescent Proteins. Submitted to Biochemistry (2007).

(4). April Ellis, and Jenny J. Yang. Metal binding Properties of His-tag Green Fluorescent Proteins. Revision to Journal of Bioinorganic Chemistry (2007).

(4) Yubin Zhou, Wei Yang, Yiming Ye, Yun Huang , Hsiau-Wei Lee, Monica M. Lurtz, Charles F. Louis, and Jenny J. Yang. Identification of the Calmodulin-Binding Domain of Connexin43. Submitted to JBC (2007).

PATENT APPLICATIONS PENDING

(1) Jenny Jie Yang. Analyte Sensor. Nonprovisional, 10/914,769 (GSU: 2003-8) (8/9/2004).

(2) Jenny Jie Yang. Grafting Method for Constructing an Analyte Binding Site. Nonprovisional, 10/914,573 (GSU: 2003-8A) (8/9/2004).

(3) Jenny Jie Yang. Computational Approach for Constructing an Analyte Binding Site. Nonprovisional, 10/914,572 (GSU: 2003-8B) (8/9/2004).

(4). Jenny J Yang, Analyte Sensors and Methods for Constructing Analyte Binding Motifs, PCT/US05/028079 (GSU: 2003-08) (8/8/2005)

(5). Jenny J Yang, Fluorescent Proteins and Use Thereof (GSU: 2004-04).

Provisional, 60/677,286 (5/3/2005)

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Non-provisional, 11/281,495 (5/3/2006)

PCT/US06/016926 (5/3/2006)

(6) Jenny J. Yang and Zhi-ren Liu. Contrast Agents and Methods for Preparing Contrast Agents (GSU: 2005-07)

Provisional Application 60/699,409 (7/13/2005).

Non-provisional, 11/457,370 (7/13/2006)

PCT/US06/027327 (7/13/2006)

(7). Jenny J Yang, Protease Sensors, Methods for Preparing and Using Such Sensors (GSU: 2005-08).

Provisional Application 60/821,490 (8/4/2006).

(8) Jenny J. Yang and Zhi-ren Liu. Targeted Contrast Agents And Methods For targeting Contrast Agents (GSU: 2005-12)

Provisional Application 60/821,493 (9/9/2005).

Non-provisional Application 11/530, 398 (9/8/2006).

PCT/US06/35221 (9/8/2006)

(9). Jenny J. Yang, Angela Holder, April Ellis and Jin Zou. Developing Sensors for Real Time Measurement of High Ca2+ Concentrations with Improved Thermal Stability and Optical properties (ISU NO: 2006-21).

US Provisional Application Pending (11/20/2006).

(10) Jenny J Yang, Zhiren Liu, Shunyi Li, MRI Contrast Agents with Improved Relaxivity, Disclosed to GSU,2006 (ISU NO: 2006-03).

US Provisional Application Pending (2007). (11). Jenny J. Yang and Ning Chen Calcium and Protein Sensors based on EF-hand dimerization

and Split Fluorescent Proteins, Disclosed to GSU, 2006 (ISU NO: 2006-22).

US Provisional Application Pending (2007).

INVITED TALKS 84. Janelia Conference of Fluorescence Proteins and Biosensors, Howard Hughes medical

Institute, Janelia Farm Research Campus, October 28, 2007 83.14th Congress of Calcium-binding Proteins and Calcium Function in Health and Disease,

La Palma, Canary Island, Spain Oct. 16, 200782. Department of Cellular Biology and Anatomy, Medical College of Georgia, August 16,

200781.Wuhan Institute of Physics and Mathematics The Chinese Academy of Sciences, Wuhan,

July 24, 200780. Huazhong Science and Technology University, Wuhan, China, July 23, 200779. College of Life Science, Zhejiang University, Hanzhou, China, July 19, 200778. Molecular Bases of Diseases symposium, Atlanta, GA, May, 8, 200777. The Medical School, the Florida State University, Tallahassee, FL, April 25, 200776. Nano-biotechnology Conference, The Third Military Medical University, Chongqing,

China, Jan. 13-4, 2007.75. Institute of Medica Biotechnology, Chinese Academy of Medical Science & Peking

Union Medical College, Beijing, R. China, Jan.10, 2007.

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74. Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, R. China, Jan.9, 2007.

73. National Analytical Research Center of Electrochemistry and spectroscopy, Changchun Institute of Applied Chemistry Chinese Academy of Sciences (CIAC), Changchun, China, Jan.8, 2007.

72. Biology Department, Brookhaven National Laboratory, Long Island, NY, Nov.,17, 2006.71. Department of Chemistry, University of Akron, OH, October, 25, 2006.70. Department of Urology, Emory University, Atlanta, GA, August 18, 2006.69. Computer and Life Science, Emory University, Atlanta, GA, July, 26, 2006.68. The 9th Meeting of the European Calcium Society, Strasbourg, France, July 22, 2006.67.The Brigham and Women’s Hospital, Department of Endocrinology, Harvard Medical

School, July, 3, 2006.66. The NMR User Group, University of Georgia, Athens, GA, May, 9, 200665. Biochemistry Department, University of Tennessee, Knoxville, TN, February 8, 200664.Winship Cancer Institute, Emory University, Atlanta, GA, January, 26, 2006.63. Symposium of Southeast NMR, Section chair and speaker, Atlanta, GA, November 12,

2005.62. Department of Chemistry, University of Georgia, Athens, GA, November.10, 2005.61. Regional Center for Biodefense and Emerging Infectious Diseases Research, University

of Chap Hill, NC, October 10, 200560. Department of Biology, Institute of Georgia Technology, Atlanta, GA, September 9,

200559. Pox Virus Branch, Centers for Disease Control and Prevention, September 8, 2005.58. Metalloprotein and Protein Design Conference, Section chair and speaker, Chicago, IL,

July 28-30, 2005.57. Department of Chemistry, University of Illinois, Chicago, IL, July

28, 200556. Second Annual Meeting of Regional Center for Biodefense and Emerging Infectious

Diseases Research, Galveston, TX, March 14, 2005.55. Suddath Symposium of Fluorescence Imaging of Cell Biology, Atlanta, April 15-16,

2005.54. Atlanta Calcium Signaling Symposium, Atlanta, April 23, 2005.53. Department of Pharmacology, John Hopkins University, Baltimore, October 13, 2004.52. Department of Chemistry, Syracuse University, Syracuse, NY, September 16, 2004.51. Harvard Medical School, VA Hospital, Boston, MA, August 16, 200450. Gordon Conference on Biomineralization, NH, July 8-15, 2004.49. Symposium of Infectious and Emerging Diseases, Atlanta, GA, January 27, 200448. Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta,

GA. 2003.47. Department of Pharmacy, Emory University, School of Medicine, Atlanta, GA, Oct.20,

2003.46. Department of Biochemistry, University of Virginia Technology, Blackblough VA, Oct.,

200345. Symposium Chair of Calcium Signaling at American Chemistry Society Southeastern

Regional Meeting, GA, November, 03.44. The National American Chemical Society, New York, NY, September 8, 2003.43. The Biophysical Society 47th Annual Meeting, San Antonio, TX, March 2-

5, 2003.

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42. Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL, November 19, 2002.

41. 3rd International Conference on High Resolution Sector Field ICPMS, Atlanta, GA, October, 2002

40. Institute of Biophysics, Chinese Academy of Sciences, Bejing, June, 2002.39. Institute of Cell Biology and Development, Chinese Academy of Sciences, Bejing, July,

200238. Institute of Neuron Science, Chinese Academy of Sciences, Shanghai, July, 200237. Department of Chemistry, TsingHua University, Bejing, July, 200236. 7th International peptide Symposium, Darlian, China, July, 2002.35. Interdisciplinary Research Center, K.U. Leuven Compus Kortrijk,

Kortrijk, B-8500, Belgium, June 18, 200234. Department of Chemistry, University of Urbana-Champaign, IL,

November 13, 01.33. Department of Chemistry, Northwestern University, Chicago, IL,

November 2, 01.32. American Chemistry Society Southeastern Regional Meeting, GA, September 25, 01.31. Department of Chemistry, University of Illinois, Chicago, IL,

November 15, 01.30. Institute of Biochemistry, Science Academy in China, Shanghai,

September, 2001.29. University of Chinese Science and Technology, College of Life Sciences, Hebei,

September, 2001.28. University of Chinese Science and Technology, Department of Chemistry, Hebei,

September, 2001. 27. National Conference of Biochemistry and Biophysics, Shanghai, September, 2001.26. Institute of Biophysics, Science Academy in China, Peking, September, 2001. 25. Department of Chemistry, Peking University, P. R. China, September, 2001.24. American Chemistry Society Southeastern Regional Meeting, GA, September 24, 01.23. University of California at Santa Barbara, CA, June, 2001.22. American Chemistry Society Southeastern Regional Meeting, GA, September 22, 2001.21. 2nd International peptide Symposium and 17th American Peptide Symposium, San Diego,

June, 2001.20. Molecular and Cellular Bioscience, National Science Foundation, Arlington, VA, June

2000.19. Department of Chemistry, University of Memphis, Memphis, TN, May 8, 2000.18. Department of Biology, Georgia State University, Atlanta, September 3, 1999.17. American Chemistry Society Southeastern Regional Meeting, University of Knoxville,

Tennessee, October 20, 1999.16. American Chemistry Society Southeastern Regional Meeting, Knoxville, Tennessee,

October 17, 1999.15. Department of Chemistry, University of South Carolina, Columbia, SC, April 27, 1999.14. Program of Physical, Materials and Computational Sciences (PMACS), Emory

University, Atlanta, Georgia, March 23, 1999.13. Department of Chemistry, Xiangtan University, Hunan, P.R. China, Oct., 1998.12. American Chemistry Society Southeastern Regional Meeting, Research Triangle Park,

NC, November, 1998.11. Department of Biochemistry, Hong Kong Polytechnic University, October, 1998.10. Department of Chemistry, Hong Kong University of Science and Technology, October,

1998.

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9. Departments of Chemistry and Biology, Georgia State University, Atlanta, Georgia, September, 1998.

8. Department of Molecular Science, University of Frankfurt, Germany, August, 19987. School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta,

Georgia, June, 1997.6. MRC Laboratory of Molecular Biology, Cambridge, UK, July, 19955. 14th American Peptide Symposium, Columbus, Ohio USA, June, 1995.4. 3rd International Symposium of Perspectives on Protein Engineering, Oxford UK, Sept. 1994.3. Institute of Molecular Medicine, Oxford, April, 1994.2. Department of Pharmacy, University of California, San Francisco, CA, Dec. 1993.1. Institute of Biochemistry and Cell Biology, Syntex Research, Palo Alto, Nov. 1993.

PRESENTATIONS, PROCEEDINGS AND ABSTRACTS AT PROFESSIONAL MEETINGS (After position at GSU, > 200 total on 107 different topics, only representative ones are listed)

1. Wei Yang and Jenny Jie Yang, “Conformational Analysis of Calcium Binding Peptides,” 15th American Peptide Symposium, Nashville, TN, August 1997.

2. Haidong Yang, Yiming Ye, Harry Hopkins and Jenny Yang, “Equilibrium Folding Studies of CD2,” 55th Annual Pittsburgh Diffraction Conference, Athens, Georgia, Nov.6-8, 1997.

3. Jenny J. Yang, Haidong Yang and Lynne Regan, “Following Protein Folding by NMR,” 38th Experimental Nuclear Magnetic Resonance Conference, Orlando, FL. March 1998.

4. Wei Yang, Tom Tsai, Mark Kats, and Jenny J. Yang, “Peptide Analogs of the Calcium Binding Loop in E-Cadherin,” Gordon conference Metals in Biology. Vantura, CA, January, 1998.

5. Yiming Ye, Haidong Yang, Harry Hopkins and Jenny Yang, “Conformational Analysis and Thermostability of Functional Mutants of Cell Adhesion Molecules,” Fladrick Symposium, Georgia, April 11, 1998 (Awarded First prize for Poster Presentation).

6. Mark, Kats, Wei Yang, Haidong Yang, Yiming Ye, and Jenny J.Yang,” Structural Analysis of Cell Adhesion Molecules by High Resolution NMR,” NSF Workshop for Metalloenzyme, Georgia July, 1998.

7. Wei Yang, Hsiau-wei Lee, Homme Hellinga, Jenny Yang, “Verifying Structural Features of Calcium Binding Proteins,” 5th Suddath Symposium on Drug Design, Georgia, April 3-5, 1998.

8. Wei Yang, Tom Tsai, Mark Kats, and Jenny J. Yang, “Peptide Analogs of the Calcium Binding Loop in E-Cadherin,” 5th International Calcium Binding Conference, Germany, Aug.1998.

9. Amy R. Carroll, Christina Nguyen, Yiming Ye, Wei Yang, and Jenny J. Yang, “An Alternated Folded Acid-stable Beta-sheet Protein,” 50th Southeastern Regional Meeting of the American Chemical Society, Research Triangle Park, North Carolina, Oct. 1998 (Awarded Second Prize for Oral Presentation).

10. Yiming Ye, Anna Walkins, Wei Yang, Zhi-ren Liu, Robert Wohlhueter and Jenny J. Yang, “Engineering of a Calcium Binding Switch into CD2,” 50 th Southeastern Regional Meeting of the American Chemical Society, Research Triangle Park, North Carolina, Oct. 1998.

11. Wei Yang, Hsiau-wei Lee, Homme Hellinga, Jenny Yang, “Identifying Calcium Binding Sites by Computer Algorithm,” 50th Southeastern Regional Meeting of the American Chemical Society, Research Triangle Park, North Carolina, Oct. 1998.

12. Haidong Yang, Yiming Ye, Harry Hopkins and Jenny J.Yang, “Formation of a Non-native Intermediate of CD2,” 50th Southeastern Regional Meeting of the American Chemical Society, Research Triangle Park, North Carolina, Oct. 1998.

13. Wei Yang, Tom Tsai, Mark Kats, and Jenny J. Yang, “Increasing Calcium Binding Affinity of E-Cadherin,” Triangle Biophysics Symposium on Principles of Protein Design: Theory, Experiments and Applications, Durham, North Carolina, Nov. 1998.

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14. Wei Yang, Hsiau-wei Lee, Homme Hellinga, and Jenny J. Yang, “Rational Design and Evaluation of Calcium Binding Sites in CD2,” 51th Southeastern Regional Meeting of the American Chemical Society, Knoxville, Tennessee, Oct. 1999.

15. Anna Wilkins, Wei Yang, April Ellis, Yiming Ye, Zhi-ren Liu, and Jenny J. Yang, “Seeking Proteins with High Calcium Binding Affinity by Coupling Rational Design and Selection,” 51th Southeastern Regional Meeting of the American Chemical Society, Knoxville, Tennessee, Oct. 1999 (Awarded First Prize for Poster Presentation).

16. Wei Yang, Hsiau-wei Lee, Homme Helinga, Zhi-ren Liu and Jenny J. Yang, “Rational Design of Calcium-binding Sites in CD2,” 8th Suddath Symposium of Biotechnology: Shaping the 21st Century. Atlanta, Georgia 2000 (Awarded First Prize for Poster Presentation).

17. Anna Wilkins, Wei Yang, Yiming Ye, April Ellis, Zhi-ren Liu and Jenny J. Yang, “Seeking Proteins with High Calcium Binding Affinity by Coupling Rational Design and Selection,” 8th Suddath Symposium of Biotechnology: Shaping the 21st Century. Atlanta, Georgia 2000 (Awarded First Prize for Poster Presentation).

18. Hsiau-wei Lee, Wei Yang, Homme Helinga and Jenny J. Yang, “Identifying of Metal-Binding Sites in Proteins,” 8th Suddath Symposium of Biotechnology: Shaping the 21 st

Century. Atlanta, Georgia 2000 (Awarded First Prize for Poster Presentation).19. Sarah Shealy, David Bostwick, Curt Coman and Jenny J. Yang, “Spectral Observation of

Two Calcium-binding Proteins by Electrospray and MALDI Mass Spectrometry,” 8th Suddath Symposium of Biotechnology: Shaping the 21st Century. Atlanta, Georgia 2000.

20. Jenny J. Yang, “Grafting, Designing and Identifying Calcium Binding Proteins,” Symposium of Metals in Biology, NIH, Bethesda, DC, June 2000.

21. Wei Yang, Hsiau-wei Lee, Homme Hellinga, Jenny J. Yang, “Identifying of Metal-Binding sites in Proteins,” 9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001.

22. Anna L. Wilkins, Wei Yang, Yiming Ye, Zhi-ren Liu and Jenny J. Yang , “The Contribution of Charge and Ligand Type to Calcium-binding Affinity,” 9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001(Awarded First Prize for Poster Presentation).

23. April L. Ellis, Christian Mason, Hyeran Lee, Lucjan Strekowski, Gabor Patonay, Jenny J. Yang, “Development and Synthesis of Calcium-sensitive Near Infrared Dyes,”9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001.

24. Amy R. Carroll, Robert Simmons, and Jenny J. Yang “Amyloid Fibril Formation by the Nonamyloidogenic Protein CD2,” 9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001(Awarded First prize for Poster Presentation).

25. Hsiau-Wei Lee, Wei Yang, Yiming Ye, Zhi-ren Liu, John Glushka and Jenny Yang ,

“Characterization of the Oligmeric State of an Isolated EF-hand Calcium-binding Loop in a Scaffold Protein by High Resolution NMR,” 9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001.

26. Wei Yang, Hsiau-wei Lee, Homme Hellinga and Jenny J. Yang, “Identification and Design of Metal-binding Sites in Proteins Using Automated Design Tools,”9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001.

27. Sarah J. Shealy, Yiming Ye, Wei Yang, and Jenny J. Yang , “Correlating Protein Rigidity with Thrombin Cleavage by Mass Spectroscopy,” 9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001.

28. Leanne Isley, Wei Yang, Hsiau-Wei Lee, Yiming Ye, and Jenny J. Yang, “Tuning Calcium binding Affinity by Protein Environment,” 9th Suddath Symposium of Structural Biology. Atlanta, Georgia 2001.

29. Yiming Ye, Hsiau-Wei Lee, Wei Yang, Sarah J. Shealy, Anna L. Wilkins, Zhi-ren Liu, Ivan Torshin, Robert Harrison, Robert Wohlhueter and Jenny J. Yang, “Metal Binding Affinity and Structural Properties of an Isolated EF-loop in a Scaffold Protein,” 2nd International peptide Symposium and 17th American Peptide Symposium, San Diego, June, 2001.

30. Wei Yang, Yiming Ye, Hsiau-wei Lee, Zhi-ren Liu,Homme Hellinga, and Jenny J. Yang, “Calcium Binding Affinity and Metal Selectivity of a De Novo Designed Calcium Binding

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Protein,” 2nd International peptide Symposium and 17th American Peptide Symposium, San Diego, June, 2001.

31. Wei Yang, Yiming Ye, Hsiau-wei Lee, Zhi-ren Liu,Homme Hellinga, and Jenny J. Yang, “Rational Design of Calcium Binding Protein,” Gordon Conference on Protein, NH, June, 2001.

32. April L. Ellis, J. Christian Mason, Hsiau-wei Lee, Lucjan Strekowski, Gabor Patonay, Hoseob Choi, Jenny J. Yang, “A Novel Near-IR Dye with a Strong Calcium Binding affinity,” SERMACS 2001, Savannah, GA September, 2001.

33. Timethia J. Booner, Anna L. Wilkins, Yiming Ye, Wei Yang, and Jenny J. Yang, “Expression, Purification, and Conformational Analysis of Designed Proteins,” Undergraduate Presentation, SERMACS 2001, Savannah, GA September, 2001.

34. Onome A. Swader, Leanne Isley, Yiming Ye and Jenny J. Yang. “Optimizing the Methods of Expression and Purification in Designed Proteins with Varying Electrostatic Environments,” Undergraduate Presentation, SERMACS 2001, Savannah, GA September, 2001.

35. Jenny J. Yang, Amy R. Carroll, Yiming Ye, Robert Simmons, and Sarah Shealy, “Conformational Change, Structural Rigidity, and Fibril Formation of a Cell Adhesion Molecule,” SERMACS 2001, Savannah, GA September, 2001.

36. Lisa Jones, Anna Wilkins, Wei Yang, Yiming Ye, and Jenny J. Yang, “Using De novo Design to Understand Calcium-dependent Conformational Change,” SERMACS 2001, Savannah, GA September, 2001.

37. Wei Yang, Yiming Ye, Hsiau-wei Lee, Zhi-ren Liu, Homme Hellinga, and Jenny J. Yang, “Structural Analysis and Rational Design of Calcium Binding Proteins,” International Conference of Biophysics and Biochemistry, Shanghai, P. R. China, September, 2001.

38. Mark Shroyer, Yiming Ye, Jenny J. Yang, Edmund P. Day, “SQUID NQDR: A new technique for studying the zero field quadrupole spectrum of 14N in 15N proteins,” 10th

International Conference of Bioinorganic Chemistry, Italy, August, 2001.39. Wei Yang, Anna Wilkins, Lisa Jones, Yiming Ye, Hsiau-wei Lee, Zhi-ren Liu, Homme

Hellinga, and Jenny J. Yang, “Rational Design of Calcium Binding Proteins,” Gordon Conference of Metals in Biology, Ventura, CA, January 21-25, 2002.

40. Yiming Ye, Hsiau-Wei Lee, Wei Yang, Anna L. Wilkins, Zhi-ren Liu, John Glushka and Jenny J. Yang, “Site Specific Binding Affinity and Structural Properties of Calmodulin,” Vantura, CA, January 21-25, 2002.

41. Wei Yang, Yiming Ye, Hsiau-wei Lee, Zhi-ren Liu,Homme Hellinga, and Jenny J. Yang, "Rational Design of Calcium Binding Protein,” 7th European Symposium on Calcium Binding Proteins in Normal and Transformed Cells,-Calcium Signaling, Brussels, June 12-15, 2002.

42. Yiming Ye, Hsiau-Wei Lee, Wei Yang, Anna L. Wilkins, Zhi-ren Liu, John Glushka and Jenny J. Yang, “New Development of Site Specific Binding Affinity and Structural Properties of Calmodulin,” 7th European Symposium on Calcium Binding Proteins in Normal and Transformed Cells,-Calcium Signaling, Brussels, June 12-15, 2002.

43. Jenny J. Yang Wei Yang, Anna Wilkins, Lisa Jones, Yiming Ye, Hsiau-wei Lee, Zhi-ren Liu, Homme Hellinga, and Jenny J. Yang, “Protein engineering of Calcium Binding Proteins with a stable structure” Gordon Conference of Metals in Biology, Ventura, CA, February 2-7, 2003.

44. Lisa Jones, Wei Yang, Yiming Ye, and Jenny Yang, “Tuning calcium affinity by protein environment,” The Biophysical Society 47th Annual Meeting, San Antonio, TX, March 2-5, 2003.

45. Anna L. Wilkins, Wei Yang, Yiming Ye, Zhi-ren Liu and Jenny J. Yang , "The Contribution of Charge and Ligand Type to Calcium-binding Affinity," The Biophysical Society 47th Annual Meeting. San Antonio, Texas, March 2003.

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46. April L. Ellis, Wei Yang, Yiming Ye, and Jenny J. Yang, "Development and Protein-based Sensors," The Biophysical Society 47th Annual Meeting. San Antonio, Texas, March 2003.

47. Jenny J. Yang, “Prediction of Calcium Binding Proteins”, Gordon Conference of Calcium Signaling, NH, July, 2003.

48. Wei Yang, Hsiau-wei Lee, Homme Hellinga, Jenny J. Yang, "Identifying of Metal-Binding sites in Proteins," Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

49. Sarah J. Shealy, Yiming Ye, Wei Yang, and Jenny J. Yang , "Correlating Protein Rigidity with Thrombin Cleavage by Mass Spectroscopy," Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

50. Jin Zou, Yiming Ye, and Jenny J. Yang, "EF-hand Motifs in GFP," Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

51. Roy Ayiteyfio, Ning Chen, and Jenny J. Yang "Expression and Purification of GFP," Poster Presentation at Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

52. Shelley Bassey, April Ellis, Anna Wilkins, and Jenny J. Yang, “Optimization of the Expression Vectors of Designed Proteins,” Oral presentation at Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

53. Dorinda Nelson, April Ellis, and Jenny J. Yang, “Purification of Calcium Sensor,” Oral presentation at Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

54. Cedrick Daphney, Anna Wilkins, and Jenny J. Yang, “Conformational Properties of Designed Calcium Binding Proteins,” Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

55. Alaya Gayatri, Hsiau-wei Lee, and Jenny Yang, “Bioinformatics of Calcium Biology”, Southeast Regional American Chemical Society, November, Atlanta, Georgia 2003.

56. Hsiau-Wei Lee, Wei Yang, Yiming Ye, Zhi-ren Liu, John Glushka and Jenny Yang, "Structural Determination of an Isolated EF-hand Calcium-binding Loop in a Scaffold Protein by High Resolution NMR," ENC, May, Savannah, GA, 2003.

57. Wei Yang, Hsiau-Wei Lee, Yiming Ye, Homme Hellinga, and Jenny J. Yang, "Structure of De novo Designed Calcium-binding Protein," ENC, May, Savannah, GA, 2003.

58. Yiming Ye, Hsiau-Wei Lee, Wei Yang, Sarah J. Shealy, Zhi-ren Liu and Jenny J. Yang, "Site-specific Metal Binding Affinity of Calmodulin," Protein Science Conference, August, Boston, MA 2003.

59. Hsiau-Wei Lee, Wei Yang, Yiming Ye, John Glushka and Jenny Yang ,

"Structure and Dynamics of an Isolated EF-hand Calcium-binding Loop in a Scaffold Protein by High Resolution NMR," The Biophysical Society 48th

Annual Meeting, Baltimore, MD, February 14-18, 2004.60. Anna L. Wilkins, Wei Yang, Yiming Ye, and Jenny J. Yang, "Metal Binding

and Conformational Properties of Designed Calcium-binding Proteins," The Biophysical Society 48th Annual Meeting, Baltimore, MD, February 14-18, 2004

61. April L. Ellis, Wei Yang, Yiming Ye, and Jenny J. Yang, "Sensing Calcium Signaling by Protein Design," The Biophysical Society 48th Annual Meeting, Baltimore, MD, February 14-18, 2004

62. Lisa Jones, Anna Wilkins, Wei Yang, Yiming Ye, and Jenny J. Yang, "Tuning Calcium Affinity and Cell Adhesion by Protein Design," The

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Biophysical Society 48th Annual Meeting, Baltimore, MD, February 14-18, 2004.

63. Yiming Ye, Hsiau-wei Lee, and Jenny J Yang, “Site-Specific Calcium Binding Affinity of EF-hand proteins,” The Biophysical Society 48th Annual Meeting, Baltimore, MD, February 14-18, 2004.

64. April Ellis, Wei Yang, and Jenny Yang “Protein Based Biosensor” 12th Suddath Symposium. Atlanta, Georgia 2004 (Awarded First Prize for Poster Presentation).

65. Jenny J Yang. “Structure of Designed Calcium Binding Proteins” Gordon Conference of Metals in Biology. January, Ventura, CA, 2004.

66. Jenny J. Yang, “Calciomics: Predicting Calcium Binding Proteins” Gordon Conference of Biomineralization. August, New London, NH, 2004.

67. Yiming Ye, Joseph Esposito, Vladimir Loparev, Mike Frace, Robert M. Wohlhueter, Inger K. Damon and Jenny J. Yang, “Understanding Molecular Recognition of the TNF Receptor Encoded by Variola Virus (smallpox) and Orthopoxvirus,” 2nd Annual Meeting of Southeast Regional Center of Excellence for Emerging Infections and Biodefense, Birmingham, AL, October 20-22, 2004.

68. Yubin Zhou, Yiming Ye,Shunyi Li, Teryl Frey, Jenny J Yang, “Structural Studies on Metal Binding Domains of Rubella Virus,” 2nd Annual Meeting of Southeast Regional Center of Excellence for Emerging Infections and Biodefense, Birmingham, AL, October 20-22, 2004.

69. Lisa Jones, Kendra Hubbard, Dan Spratt, Wei Yang, and Jenny J. Yang, "Modulating Calcium Affinity and Cell Adhesion by Environment," 11th Suddath Symposium of Fluorescence Imaging of Life Sciences. Atlanta, Georgia 2005 (Awarded First Prize for Poster Presentation).

70. Yubin Zhou, Teryl Frey, and Jenny J.Yang. Characterization of Metal Binding Domains within Rubella Virus Nonstructural Protease. 11th Suddath Symposium of Fluorescence Imaging of Life Sciences. Atlanta, Georgia 2005.

71. April L. Ellis, Wei Yang, Yiming Ye, Monica Lurtz, Charles Louis, Jenny J. Yang “Rational Design of Calcium Biosensors”. 3rd Georgia State University Biotechnology Symposium-Molecular Bases of Diseases-Atlanta, Georgia 2005.

72. Hsiau-wei Lee, Yiming Ye, and Jenny Yang "Probing Site-Specific Calcium Binding Properties of EF-hand Proteins by Grafting and NMR" Symposium-Molecular Bases of Diseases-Atlanta, Georgia 2005.

73. Yiming Ye, Joseph Esposito, Vladimir Loparev, Mike Frace, Robert M. Wohlhueter, Inger K. Damon and Jenny J. Yang, “Understanding Molecular Recognition of the TNF Receptor Encoded by Variola Virus (smallpox) and Orthopoxvirus,” Southeast Regional Center of Excellence for Emerging Infections and Biodefense, Galveston, TX, 2005.

74. Jenny J. Yang, “Calcium Binding Proteins and Calcium Signaling” 14th

International calcium Binding Proteins and Diseases. Banff, Canada, 2005.

75. Lisa M. Jones, Wei Yang, Anna L. Wilkins, Alice Kearney, P. Anton van der Merwe, and Jenny J. Yang “Rational Design of a novel calcium binding site adjacent to the ligand binding site on CD2 increases its adhesion function”. Metalloprotein Design and Protein Folding Conference. Chicago, IL, 2005

76. GT Chen, Hai Deng, Wei Yang and Jenny J. Yang. “Identifying and Predicting Calcium Binding Sites in Proteins using Graph and Geometry Algorithms. Metalloprotein Design and Protein Folding Conference. Chicago, IL, 2005

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77. Yubin Zhou, Michael Kirberger, Hsiau-Wei Lee, Gayatri Ayalasomayajula, Wei Yang, and Jenny J.Yang. Prediction of EF-hand and EF-like calcium binding proteins Metalloprotein Design and Protein Folding Conference. Chicago, IL, 2005

78. Anna L. Wilkins, Wei Yang, Shun-yi Li, Julian Johnson, and Jenny J. Yang .

Design of Calcium binding Proteins with Different Metal Binding Affinities Metalloprotein Design and Protein Folding Conference. Chicago, IL, 2005

79. Yubin Zhou, Teryl Frey, and Jenny J.Yang. Characterization of Metal Binding Domains within Rubella Virus Nonstructural Protease.Metalloprotein Design and Protein Folding Conference. Chicago, IL, 2005

80. Ning Chen, Yiming Ye, Jin Zou, Shunyi Li, Siming Wang, Amy Mertin, Robert Wohlhueter and Jenny J. Yang. Developing Mini Green Fluorescent Proteins. Metalloprotein Design and Protein Folding Conference. Chicago, IL, 2005

81. Lisa Jones, Kendra Hubbard, Dan Spratt, Wei Yang, and Jenny J. Yang, "Modulating Calcium Affinity and Cell Adhesion by Environment," 11th Suddath Symposium of Fluorescence Imaging of Life Sciences. Atlanta, Georgia 2005 (Awarded First Prize for Poster Presentation).

82. Shunyi Li, Wei Yang, Anna Wilkins, and Jenny Yang, “In-cell NMR and Calcium-Dependent Proteins by Design,” 11th Suddath Symposium of Fluorescence Imaging of Life Sciences. Atlanta, Georgia 2005.

83. Yubin Zhou, Teryl Frey, and Jenny J.Yang. Intrinsic calcium binding motif within Rubella Virus Nonstructural Protease. Atlanta Calcium Signaling Symposium, Atlanta, GA, 2005.

84. Ning Chen and Jenny J. Yang, “Development of EGFP-based Trypsin and Chymotrypsin Sensors,” Atlanta Calcium Signaling Symposium, Atlanta, GA, 2005.

85. Wei Yang, Anna Wilkins, Shun-yi Li, and Jenny J. Yang, Dynamic propertied of Designed Calcium-binding Proteins. Atlanta Calcium Signaling Symposium, Atlanta, GA, 2005.

86. Jin Zou, Ning Chen, and Jenny J Yang, “Developing GFP-based Calcium Sensors by Grafting,” Atlanta Calcium Signaling Symposium, Atlanta, GA, 2005.

87. Anna Wilkins, Wei Yang, Julian Johnson, and Jenny J Yang, “Analyzing the effects of net charge and ligand type to the metal binding affinities for designed calcium binding proteins,” Atlanta Calcium Signaling Symposium, Atlanta, GA, 2005.

88. Julian Johnson, Anna Wilkins, Shun-yi Li, and Jenny J Yang, “Thermal stability and Biochemical studies of designed calcium binding proteins,” Atlanta Calcium Signaling Symposium, Atlanta, GA, 2005.

89. Yuan Huang, April Ellis and Jenny Yang, “Determinants for the Optical Properties of DesRed fluorescent Proteins,” 5th Southeast Multiphoton Confocal Conference, Atlanta, Georgia 2005.

90. Jin Zou, Ning Chen, and Jenny J Yang, “Developing GFP-based Calcium Sensors by Grafting,” 5th Southeast Multiphoton Confocal Conference, Atlanta, Georgia 2005.

91. April Ellis and Jenny J Yang “Rational Design of Calcium Biosensor-pH and Metal binding properties,” 5th Southeast Multiphoton Confocal Conference, Atlanta, Georgia 2005.

92. Jenny Yang “Rational Design of Metal-Binding Proteins for Molecular Imaging by MRI and Fluorescence Microscopy” Imaging in 2020 Conference,-Molecular Imaging, Jackson Hole, Wyoming, 2005.

93. Yiming Ye, Joseph Esposito, Vladimir Loparev, Mike Frace, Robert M. Wohlhueter, Inger K. Damon and Jenny J. Yang, “Understanding

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Molecular Recognition of the TNF Receptor Encoded by Variola Virus (smallpox) and Orthopoxvirus,” Southeast Regional Center of Excellence for Emerging Infections and Biodefense, Chapel Hill , NC, 2005.

94. Jenny Yang, Yiming Ye, Robert M. Wohlhueter, Kevin Karem, and Inger K. Damon, “Molecular Recognition of Monkey Pox Virus for Specific Detection,” Southeast Regional Center of Excellence for Emerging Infections and Biodefense, Chapel Hill , NC, 2005.

95. Yubin Zhou, Yiming Ye, Wei Yang, Yumei Zhou, Teryl Frey, Jenny J Yang, “Exploring the role of Ca2+ in virus life cycle by prediction and engineering,” Southeast Regional Center of Excellence for Emerging Infections and Biodefense, Chapel Hill , NC, 2005.

96. Jenny J Yang, “New Approaches for Molecular Imaging,” 50th Annual Biophysical Society Meeting, Salt Lake City, Utah, 2006.

97. Lisa Jones, Kendra Hubbard, Wei Yang, and Jenny J. Yang, "Modulating Calcium Affinity and Cell Adhesion by Electrostatic Interaction," 50th Annual Biophysical Society Meeting, Salt Lake City, Utah, 2006.

98. Jenny J Yang “Design calcium sensors without using natural calcium binding proteins and FRET” Frontier of Cell Imaging, NIH, April 2006.

99. Ning Chen, Jin Zou, Wei Yang, and Jenny J. Yang, “Development of EGFP-based Sensors for Live Cell Imaging,” 14th Suddath Symposium of Single Molecule Dynamics in Biology. Atlanta, Georgia, April, 2006.

100.Shunyi Li, Wei Yang, Anna Wilkins, Doyle Barrow, Jr. and Jenny Yang, “Rational Design of Switchable Calcium and Lanthanide Binding Proteins”, 14th Suddath Symposium of Single Molecule Dynamics in Biology. Atlanta, Georgia, April, 2006.

101.Julian Johnson, Anna Wilkins, Shun-yi Li, and Jenny J Yang, “The Effect pf Net Charge and Ligand type on Stability and Calcium Affinity” 14th Suddath Symposium of Single Molecule Dynamics in Biology. Atlanta, Georgia, April, 2006.

102.Jianhua Yang, Lixia Wei, Shunyi Li, Wei Yang, Jenny J. Yang and Zhien Liu, “Developing Protein-Based Contrast Agents,” 14th Suddath Symposium of Single Molecule Dynamics in Biology. Atlanta, Georgia, April, 2006.

103.Yun Huang, and Jenny Yang, “Dissect Calcium Binding Sites In Calcium Sensing Receptor by Grafting and Subdomain Approach”, 14th Suddath Symposium of Single Molecule Dynamics in Biology. Atlanta, Georgia, April, 2006.

104.Lisa Jones, Jenny Yang, “Structural Biology of A Novel Calcium Binding Protein” 14th Suddath Symposium of Single Molecule Dynamics in Biology. Atlanta, Georgia, April, 2006.

105.Yubin Zhou, Wei Yang, Teryl Frey, and Jenny Yang “Probing the Ca2+-Binding Properties of the Rubella Virus Nonstructural Protease” '25th Annual Meeting of the American Society of Virology, Madison, Wisconsin, July, 2006

106.Yuan Huang, Wei Yang, Yubin Zhou, and Jenny J Yang, “Prediction of calcium binding sites in G-Protein Coupled Receptor,” 9th Meeting of the European Calcium Society, Strasbourg, France, August, 2006.

107.Jin Zou, Aldebaran M. Hofer, Monica Lurtz, Giovanni Gadda, April L. Ellis, Ning Chen, Yun Huang, Angela Holder, Yiming Ye, Charles Louis, Kristy Welshhans, Vincent Rehder, and Jenny J. Yang, “Developing Sensors for Real Time Imaging of High Calcium Concentrations”. National American Chemical Society, Atlanta, GA, 2006.

108.Shunyi Li, and Jenny Yang, “Probing Metal Binding of Designed Calcium-Binding Proteins by Mass Spectrometry,” National American Chemical Society, Atlanta, GA, 2006.

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109.Lev Shaket, Julian Johnson, Jenny J. Yang, “Improve Designed Calcium Binding Proteins”, the National Junior Science and Humanities Symposium in Albuquerque, New Mexico, 2006 (2nd place), International Science and Engineering Fair in Indianapolis, Indiana, 2006 (First Prize)

COURSES TAUGHT

1985 Undergraduate Analytical Chemistry1986 Undergraduate Instrumental Analysis1987 Undergraduate Inorganic Chemistry Labs1987-89 Undergraduate Analytical Chemistry LabsWinter 98 Graduate/Undergraduate Biochemistry I Chem 460/660Fall 97 Graduate Advanced Protein Chemistry Chem 862Spring 97 Graduate/Undergraduate Biochemistry I Chem 460/660Winter 98 Graduate/Undergraduate Biochemistry I Chem 460/660Spring 98 Graduate/Undergraduate Biochemistry I Chem 4600/6600Spring 98 Graduate From DNA to Protein (Topics) Bio 896Fall 98 Graduate/Undergraduate Protein Structure & Functions Chem 8360Fall 98 Graduate Biomolecular NMR Chem 8900PSpring 99 Graduate/Undergraduate Biochemistry II Chem 4610/6610Fall 99 Graduate Biomolecular NMR Chem 8500Spring 00 Graduate/Undergraduate Biochemistry II Chem 4610/6610Fall 00 Graduate Protein Structure & Functions Chem 8360Spring 01 Graduate/Undergraduate Biochemistry II Chem 4610/6610Fall 01 Graduate Biomolecular NMR Chem 8500Spring 02 Graduate/Undergraduate Biochemistry II & molecular Basis for Diseases

Chem 4610/6610Fall 02 Graduate Protein Structure & Functions Chem 8360

Biomolecular NMR Chem 8500Spring 03 Graduate/Undergraduate Biochemistry II & molecular Basis for Diseases

Chem 4610/6610Fall 03 Graduate Protein Structure & Functions Chem 8360Spring 04 Graduate/Undergraduate Biochemistry II & molecular Basis for Diseases

Chem 4610/6610Biomolecular NMR Chem 8500 for GSU, UGA Georgia Tech, and Emory

Fall 04 Graduate/Undergraduate Enzymology Bio/Chem 4630/6630Fall 04 Graduate/Undergraduate Molecular Interaction-Protein and Enzyme

Chem 8540/6540Fall 04 Graduate/Undergraduate Current Topics in Chemistry-seminar

Chem8800Spring 05 Graduate/Undergraduate Molecular Interaction-Protein and Enzyme

Chem 8540/6540Spring 05 Graduate Biomolecular NMR Chem 8500Spring 06 Graduate/Undergraduate Biochemistry II & molecular Basis for Diseases

Chem 4610/6610Spring 06 Graduate/Undergraduate Molecular Interaction-Protein and Enzyme

Chem 8540/6540Fall 06 Graduate Protein Structure & Functions Chem/Bio 8360Spring 07 Graduate/Undergraduate Biochemistry II & molecular Basis for Diseases

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Chem 4610/6610

STUDENT AND POSTDOCTORAL ASSOCIATES, PAST AND PRESENT

Research Scientists and Postdoctoral FellowsDr. Jin Zou 2002 - present Research ScientistDr. Shunyi Li 2004 - present Research ScientistDr. Hing C. Wong 2007 – present Research ScientistDr. Hsiau-wei Lee 2007 - present Postdoctoral Associate

Dr. Wei Yang 2001 – 2007.3 Research Scientist

(Now Professor at the National applied Chemistry Institute at Changchun, PR. China)

Dr. Yiming Ye 2001 – 2005 Research Scientist (now researcher at CDC joint project)

Dr. Mingshen Wang 2002 – 2003 Postdoctoral AssociateDr. Anna wilkins Mannicia 2006 Postdoctoral Associate

(now Postdoc. at the Georgia Cancer Center)Dr. Jianhua Yang 2004 – 2007.1 Postdoctoral Associate joint with Dr. Zhi-ren Liu

Ph.D. Graduate Students

Yubin Zhou 2004 - present Ph.D. Candidate Biochemistry, MBD predoctoral fellowshipNing Chen 2005 - present Ph.D. Student BiochemistryYuan Huang 2005 - present Ph.D. Student Biochemistry, B& B predoctoral FellowshipJingjuan Qiao 2006 - present Ph.D. Student BiochemistryJie Zhang 2006 - present Ph.D. Student BiochemistryShen Tang 2006 - present Ph.D. Student BiochemistryYanyi Chen 2007- present Ph.D. Student BiochemistryYuSheng Jiang 2007- present Ph.D. Student BiochemistryHai Deng 2004 - present Ph.D. Student Math and Computer Science P20 Fellowship

under Dr. GT ChenShirley Wang 2007- present Ph.D. Student Math and Computer Science P20 Fellowship

under Dr. GT Chen

Wei Yang 1997- 2001 Ph.D. BiologyYiming Ye 1998- 2002 Ph.D. Biochemistry

(now research at CDC) Anna Wilkins 1999 - 2005 Ph.D. Biochemistry NIH predoctoral Fellowship

Chair’s Award 2003 (now Medical Writer. at International Medical

Press )April Ellis 2000 - 2006 Ph.D. Biochemistry American Heart Association and

B& B predoctoral Fellowship(now research scientist at Agentabiotechnologies,

Inc.Lisa Jones 2001 - 2006 Ph.D. Biochemistry GANN predoctoral fellowship

Instruction Award, FASEB/MARC Travel Award(now postdoc. at University of Alabama at

Birmingham)

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Hsiau-wei Lee 2000 – 2007.4 Ph.D. Structural Biology, MBD predoctoral fellowshipChair’s Award 2005

Michelle Pu 1998-1999

M.S. Graduate Students

Julian Johnson 2006 – presentYanyi Chen 2006 – presentAdriana Castiblanco 2007- present

Michael Kirberger 2003 – 2007. 4Angela Holder 2004 – M.S. 2006 now at CDCNing Chen 2003 - M.S. 2005Aayala Gayatri 2003 - M.S. 2004Meredith Pyle 2003 - M.S. 2005Sarah Shealy 2000 - M.S. 2003Amy Carroll 2000 - M.S. 2001 M.D. at Texas ClinicLeanne Isley 2000 - M.S. 2001Lisa Jones 2001 - M.S. 2003Hsiau-wei Lee 1999 - M.S. 2000 Awarded for best poster presentationAnna Wilkins 1998 - M.S. 1999 Awarded for best poster presentation, teaching EL-Hadji Sarr 1998 - M.S. 1999 African-AmericanHaidong Yang 1996 - M.S. 1998Curt Coman 2000 - 2001Tom Tsai 1997 - 1998Gordon Bivens 1999 -2000 Medina S. Jackson 2004 -2005

Undergraduate StudentNatalie Moore 2007- present Molecular Bases of Diseases FellowJen Nego 2007- present 2007- present

David Mpofu 2006 – present McNair Fellowship for Minority studentAdriana Castiblanco 2006 Hispanic/Colombia,Honors and Distinction in ResearchJulian Johnson 2004 - 2006 Supported by the NIH Supplement grant

Southeastern Conference of Undergraduate Research, best oral presentation award, 2005Nolen Award for Best undergraduate student

Kendra Hubbard 2004 - 2006 Presidential and MBD FellowshipAlice Luo 2004 - 2005 AURA Fellowship, Institute of Georgia TechnologyDaniel Sprat 2004 – 2005 Instruction awardDorinda Nelson 2003 Minority Student supported by the Bridge ProgramThanh K. Quach 2004 Minority Student Supported by the McNair FellowshipCedrick Daphney 2003 - 2004 McNair Fellowship for Minority studentRoy Ayiteyfio 2002 - 2003 McNair Fellowship for Minority studentShealey Bassey 2002 - 2003 McNair Fellowship for Minority, University of Georgia

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Michael Kirberger 2001 - 2003Angela Holder 2001 - 2003Shane Johnson 2001 - 2003 NSF Supported Minority ResearchOnome Swader 2001 - 2003 McNair Fellowship for Minority Research Timethia Bonner 2001 NSF-sponsored minority research for Tuskegee Univ.Amy Carroll 1998 - 00 Honors and Distinction in research,

2nd Prize awarded for Oral Presentation Regional ACSAnnie Lin 1998 - 00April Ellis 1999 - 00 Distinction in ResearchPayal Shah 1999 - 00Hsiau-wei Lee 1998 - 99 Distinction in ResearchMark Kats 1997 - 98 Georgia Institute of TechnologyChristina Nguyen 1997 - 98 Honors and Distinction in ResearchAnna Wilkins 1998Chris Morley 1998Trung Tran 1997

Non-Degree/postgraduateAnnie Lin 2000Amy Gawthrop 2002 Sangeeta Dave 2002 Yan Xiao 2004 – 2005

Technicians/Research AssociateMichael Kirberger 2007 - presentXiu-qin Zhou 2001Qian Li 2002

High School StudentLev Shaket 2005-2006 Chamblee High Grand Prize at Dekalb-Rockdale Regional Science and Engineering Fair ($50 + all-expense paid trip), GA, 20062nd place at Georgia Junior Science and Humanities Symposium ($1000 + all-expense paid trip) Athens, GA, 20062nd place at the National Junior Science and Humanities Symposium in Albuquerque, New Mexico, 2006 First Prize, International Science and Engineering Fair in Indianapolis, Indiana, May 7-13, 2006

REFERENCES:Professor Charles F. LouisVice Chancellor of Research and Professor of Cell BiologyUniversity of California RiversideRiverside, CA 92521Tel: 909/[email protected]    Professor Jim H. Prestegard,

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University of GeorgiaComplex Carbohydrate Research Center220 Riverbend Rd, Athens, GA 30602Phone: 706-542-6281FAX: [email protected]   

Wei Yang, Ph. D.Section Chief of Structure and MechanismLaboratory of Molecular BiologyNIDDK, NIH9000 Rockville Pike, Bldg. 5, Rm B1-03Bethesda, MD 20892email: [email protected]: (301)402-4645fax: (301) 496-0201url: www-mslmb.niddk.nih.gov

Professor  Rajini RaoAssociate ProfessorDepartment of Physiology Room 201Wood Basic Science Building410-955-4732410-955-0461 (Fax)[email protected]    Professor Jeffery UrbauerUniversity of GeorgiaDepartment of Chemistry University of GeorgiaAthens, GA 30602-2556Office: A308A Life Sciences Lab: A310 Life SciencesTel: [email protected]    

6/21/2007

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