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CURRICULUM VITAE Mohammed Mohsin A. Safhi, Ph.D.
Dean, Faculty of Pharmacy
Personal
Information
Marital Status:
Married
Nationality: Saudi
Date of birth April 09, 1975
Phone Home +966-73217668
Mobile +966-567795950
E-mail [email protected]
Education October 2004 -
July 1, 2008
Ph.D. in Molecular Pharmacology, Institute of
Biomedical and Life Science, University of Glasgow,
UK
Work
Experience
1998-2000 Teaching Assistance, in College of Health Science,
Jazan, Saudi Arabia.
2002-2003 Lecturer of Medical Biochemistry, College of Health
Science, Jazan Saudi Arabia.
2002-2003
Manager of Training, in College of Health Science,
Jazan, Saudi Arabia.
July-2008 Assistance Professor of Molecular Pharmacology,
Faculty of Applied Medical Science, Jazan University,
Jazan, Saudi Arabia.
October 2008
Supervisor of academic purpose, Faculty of Applied
Medical Science, Jazan University, Jazan Saudi Arabia.
March 2009
Supervisor of scholarship Department, Jazan
University, Jazan, Saudi Arabia.
September
2009
Dean, Faculty of Pharmacy, Jazan University, Jazan,
Saudi Arabia.
Professional
Qualifications
2006 Selected for oral communication in the conference of
Bioscience 2006, Bioscience for the 21st Century,
SECC, Glasgow, UK, 23-27 July 2006.
2006 Selected for Promega UK Young Biochemist 2006
Competition (as one of best 6 researchers out of 600).
2
2007
Selected for oral communication in the conference of
Bioscience 2007, Bioscience SECC, Glasgow, UK, 8-12
July 2007
January 19-21,
2009
Workshops of the First International Saudi Conference
for Health Education and Training Riyadh, Saudi
Arabia
April 20-22,
2009
Workshop on "Molecular Biology Techniques:
Principles and Applications" Abha, Saudi Arabia
May 13-16,
2009
Workshop on Working Toward Program
Accreditation. Jazan University, Saudi Arabia.
26-4-2010 Workshops on the Pharmacy Curriculum
28-7-2009- 8-
8-2009
Training Program for E Learning and Distance Learning,
Japan
August 9-15,
2011
Teaching in Higher Education, Dubai, UAE.
Affiliation 2005-2008 Member of Biomedical Society
2009-till date Member of university time tables committee
2009-till date Permanent member of the committee for scholarships
and training
2009-till date Member of the university consulting committee
2009-till date Member of university senate
2009-till date Member of the national deans of pharmacy colleges
association
2010- till date Permanent member of the committee for educational
affairs
2009-2010 Member of the committee for planning and curriculum
development
2011- till date Member of Drug Abuse Center
2011-till date Member of the forensic medicine committee for Aseer
region
2011-2012
Member of Biomedical Society
2009-2012 Member of Saudi Pharmaceutical Society
3
CURRENT FINANCIAL SUPPORT:
No. DETAILS
1. Title
Role in Project
Awarding body
Study the action of KHAT on the brain lipids
Principal Investigator
Substance Abuse Research Center, Jazan University, KSA
2009-2011 Member of American Society for Pharmacology and
Experimental Therapeutics
Conferences
July 17-21,
2005
Bioscience 2005, From Genes to Systems, SECC,
Glasgow, UK.
May 24-28,
2006 8
th International Symposium on Adenosine and
Adenosine Nucleotides, Ferrara, Italy.
July 23-27,
2006
Bioscience 2006, Bioscience for the 21st Century,
SECC, Glasgow, UK.
July 8-12,
2007
Bioscience 2007, SECC, Glasgow, UK.
July 8, 2007 Life Science, The Young Life Scientists Symposium,
University of Strathclyde, Glasgow, UK.
January 19-21,
2009
The First International Saudi Conference for Health
Education and Training Riyadh, Saudi Arabia.
April 26-28,
2010 The 8
th Saudi International Pharmaceutical
Conference and Exhibition Riyadh, Saudi Arabia
June 27-29,
2011
Advances in the cellular and molecular biology of
angiogenesis.
February 27th
2013
3rd
Medical Research Day, Organized by Faculty of
Medicine, Jazan University
10th
Feb 2015
One day Seminar on “National Workshop on Khat
Biomedical Research” Organized by Substance Abuse
Research Centre (SARC), Jazan University, Gizan
15-17 Feb2015 Three days International Conference on “Clinical
Pharmacy”, Organized by College of Pharmacy, Al-
Qassim University, Qassim, Saudi Arabia.
Awards &
Achievements
March 2014
Accredited and recognized by the International
Accreditation Organization (IAO), U.S.A
4
Award period
Funding Amount
September 1, 2011-June 30, 2011
SAR 160,000
2. Title
Role in Project
Awarding body
Award period
Funding Amount
Action of khat on neurotransmitters
Co-Investigator
Substance Abuse Research Center, Jazan University, KSA
September 1, 2011-June 30, 2011
SAR 165,000
3. Title
Role in Project
Awarding body
Award period
Funding Amount
Mechanistic approach of tellurium toxicity
Principal Investigator
Research Deanship, Jazan University, KSA
October 2014 – September 2015
SAR 60,000
4. Title
Role in Project
Awarding body
Award period
Funding Amount
Formulation and encapsulation of nanoparticles of curcumin
and piperine for the treatment of cerebral ischemia.
Co-Principal Investigator
KACST, Jazan
October 2014 – September 2016
SAR 2,000,000 (2 million)
PATENT:
Title: “Production and purification of the antibiotic Xenohagxin from Exnorhabdus
indica”
Year of patent: 06-11-2014
Patent Approval Number: 114350583
Patent Approved by KACST, Saudi Arabia
SCIENTIFIC ABSTRACTS:
1. Hussein Abdelhady Aboulhag, Mohammed M. Safhi. F-258- Xenohagxin: New
proteinaceous antibiotic derived from Xenorhabdus indica. American Society for
Microbiology Sept 5-6, 2014, Washington DC, USA.
2. Barik B. B, M. M. Safhi, Santanu Ghosh. A comparative BA/BE study of
conventional and sustained-release tablet formulations of Aceclofenac in healthy
male subject. 4th
World Congress on "Bioavailability and Bioequivalence:
Pharmaceutical R&D Summit, 20-22 May 2013, Beijing, China.
5
3. Hussein Abdelhady Aboulhag, Mohammed M. Safhi. Assessment of immune
response against HIV-1 P24 antigen using Bacillus thuringiensis serovar Dakota
(H15) activated delta-endotoxin as an adjuvant. American Association of
Immunologists (AAI) Annual Meeting, Immunology 2013, May 3-7, Honolulu,
Hawaii.
4. S. M. Kumar, Mohammed M. Safhi. Vaccine adjuvants- present and future concepts.
BIT's 5th
Annual World Congress of vaccine 2013, Hangzhou, China.
5. Tamanna Jahangir, Mohammad M. Safhi. A natural compound alleviates
hepatotoxicity in Wistar rats: possible role of NfKB, caspases? ECOPRAM 2012,
Istanbul,Turkey.
6. Tamanna Jahangir, Mohammad M. Safhi. Natural plant product protects against 2-
acetoaminoflourine induced hepatotoxicity. 4th
World cancer congress May 22-25,
2011, Dalian ,China
7. Abouelhag HA, Safhi MM. Agarose slide elisa for diagnosis of HCV-AB in rural
areas. Presented in the 18th Annual meeting of the American Association of
Immunology held on May 13-17, 2011.
8. Barik B, Safhi MM, Dinda A, Biswal I. Preparation of Budesonide loaded
nanoparticles: Effect of stabilizers. Presented in fourth annual nanotechnology
symposium held on September 23-24, 2011 in Sullivan University College of
Pharmacy, Louisville, Kentucky, USA.
9. Safhi MM. Priming of STATs for cytokine-triggered polyubiquitylation and
degradation upon A2A adenosine receptor (A2AAR) expression in vascular
endothelial cells. Life Science July 8-12, 2007, Glasgow, UK.
10. Safhi MM. Priming of STAT1 and STAT3 for cytokine-triggers degradation by the
proteasome upon A2A Adenosine receptor (A2AAR) expression in human umbilical
vein endothelial cells. Bioscience 23-27, 2006, Glasgow, UK.
PUBLICATIONS:
1. Rizwana Tabassum, Kumar Vaibhav, Pallavi Shrivastava,Andleeb Khan, Mohd
Ejaz Ahmed, Mohammad Ashafaq, M Badruzzaman Khan, Farah Islam,
Mohammed M Safhi, Fakhrul Islam. Perillyl alcohol improves functional and
histological outcomes against ischemia-reperfusion injury by attenuation of
oxidative stress and repression of COX-2, NOS-2 and NF-κB in middle cerebral
artery occlusion rats. European Journal of Pharmacology 2015; 747: 190-199 doi:
10.1016/j.ejphar.2014.09.015 (Impact Factor - 2.68)
2. Hayate Javed, Kumar Vaibhav, M Ejaz Ahmed, Andleeb Khan,Rizwana
Tabassum, Farah Islam, Mohammed M Safhi, Fakhrul Islam. Effect of hesperidin
on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in
intracerebroventricular streptozotocin induced cognitive impairment in mice.
Journal of Neurological Sciences 2015; 348(1-2): 51-59 doi:
10.1016/j.jns.2014.10.044. (Impact Factor - 2.26)
6
3.Mohammad Sarfaraz Alam, Mohammad Sajid Ali, Mohammad Intakhab Alam,
Tarique Anwer, Mohammed Mohsen A Safhi. Stability Testing of Beclomethasone
Dipropionate Nanoemulsion. Tropical Journal of Pharmaceutical Research,
January 2015; 14 (1): 15-20.
4. Nakul Gupta, Mohammed M. Safhi, Yousra Nomier, Maryam Nayeem, Syed
Mamoon Husain, Pankaj Tripathi, Meetu Agarwal. Chemoprotective Effect of
Leucas aspera Plant in Rats: DEN Induced Hepatocarcinogenesis. International
Journal of Pharmaceutical Sciences Review and Research 2015; 30(1):22-27.
5. Mohammed M Safhi, Alam MF, Hussain S, Siddiqui MAH, Khuwaja G, Khardali
IAJ, Al-Sanosi RM, Islam F. Cathinone, an active principle of Catha edulis,
accelerates oxidative stress in the limbic area of Swiss albino mice. Journal of
Ethnopharmacology 2014; 156; 102-106. (Impact Factor - 2.93)
6. Andleeb Khan, Kumar Vaibhav, Hayate Javed, Rizwana Tabassum, Md Ejaz
Ahmed, Mohd Moshahid Khan, M Badruzzaman Khan, Pallavi Shrivastava, Farah
Islam, M Saeed Siddiqui, M. M. Safhi, Fakhrul Islam. 1,8-Cineole (Eucalyptol)
Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to
Alzheimer's Disease. Neurochemical Research 2014; 39: 344 – 352. DOI
10.1007/s11064-1231-9 (Impact Factor - 2.13)
7.Gyas Khan, S. E. Haque, Tarique Anwer, M. N. Ahsan, M.M. Safhi, M. F. Alam.
Cardioprotective effect of green tea extract on doxorubicin-induced cardiotoxicity in
rats. Acta Poloniae Pharmaceutica - Drug Research 2014; 71(5): 861-868.
(Impact Factor – 0.67)
8.Masoom Raza Siddiqui, Md. Sarfaraz Alam, Mohammed M. Safhi, Md. Sajid Ali.
Application of Persulphate for the Quantitative Analysis of Ceftriaxone in
Pharmaceutical Formulations. Advanced Science, Engineering and Medicine 2014;
6(2):231-234.
9. Mohammed M. Safhi, Mohammad Firoz Alam, S.M. Sivakumarb, Aamena Jabeen,
Tarique Anwer, Gyas Khan, Fakhrul Islam. Antibacterial spectrum of black seed oil
against selected human pathogenic bacteria. Journal of Pharmacy Research 2014:
8(11); 1726-1728
10. Mohammed M Safhi, Sivakumar S, Aamena Jabeen, Foziya Zakir, Farah Islam,
B.B Barik. Chitosan nanoparticle as a sustained Penicillin G delivery prepared by
ionic gelatin technique. Journal of Pharmacy Research 2014: 8(10); 1352-1354.
11. Mohammed M Safhi, Alam MF, Khardali IAJ, Hussain S, Siddiqui MAH,
Khuwaja G, Al-Sanosi RM, Islam F. Toxic effect of cathinone (an active principle
of Catha edulis) on brain lipids in Swiss albino mice. Environment Conservation
Journal 2014; 15(1&2): 5-11. (Impact Factor – 0.58)
12. Mohammed M Safhi. Seaweed as potential resources of antimicrobials “An
Outline”. Research J. Pharm Tech 2014; 7(10): 1178-1180.
7
13. Nakul Gupta, Prerna Chauhan, Maryam Nayeem, Mohammed M Safhi, Meetu
Agarwal. Hepatoprotective effect of Caesalpinia crista Linn. against CCl4 and
paracetamol induced hepatotoxicity in albino rats. African Journal of Pharmacy
and Pharmacology 2014; 8(18): 485-491. (Impact Factor – 0.84)
14. Meetu Agarwal, Maryam Nayeem, Mohammed M Safhi, Nakul Gupta, Hafiz A
Makeen, Jameel MY Sumaily. Prescribing pattern of drugs in the department of
Obstetrics and Gynecology in expected mothers in Jazan region, KSA.
International Journal of Pharmacy and Pharmaceutical Sciences 2014; 6(1):
658-661. (Impact Factor – 1.59)
15. Alam MF, Mohammed M Safhi, Sivakumar SM, Anwer T, Khan G, Islam F.
Antibacterial toxicity of sodium tellurite (ST) against selected bacterial strains.
Research J. Pharm Tech 2014; 7(5): 499-501.
16. Sivakumar S. M, Mohammed M Safhi, Bhakti B Barik. Nanoparticles for
triggering and regulation of immune response of vaccines: Perspective and
prospective. Current Pharmaceutical Biotechnology 2013: 14; 1242-1249. Impact
Factor - 2.69)
17. Kumar Vaibhav, Pallavi Shrivastava, Rizwana Tabassum, Andleeb Khan, Hayate
Javed, Md. Ejaz Ahmed, Farah Islam, M. M. Safhi, Fakhrul Islam. Delayed
administration of zingerone mitigates the behavioral and histological alteration via
repression of oxidative stress and intrinsic programmed cell death in focal transient
ischemic rats. Pharmacol Biochem Behav 2013; 15(113): 53-62. DOI:
10.1016/j.pbb.2013.10.008. (Impact Factor - 2.61)
18. Javed H, Khan A, Vaibhav K, Moshahid Khan M, Ahmad A, Ejaz Ahmad M,
Ahmad A, Tabassum R, Islam F, Safhi M.M, Islam F. Taurine ameliorates
neurobehavioral, neurochemical and immunohistochemical changes in sporadic
dementia of Alzheimer's type (SDAT) caused by intracerebroventricular
streptozotocin in rats. Neurological Sciences 2013; 34 (12): 2181-2192. DOI
10.1007/s00709-013-0482-2. (Impact Factor – 1.41)
19. Ahmad ME, Javed H, Khan MM, Vaibhav K, Ahmad A, Khan A, Tabassum R,
Islam F, Safhi MM, Islam F. Attenuation of oxidative damage-associated cognitive
decline by Withania somnifera in rat model of streptozotocin-induced cognitive
impairment. Protoplasm 2013; 250(5): 1067-1078. DOI 10.1007/s00709-013-0482-
2. (Impact Factor - 2.86)
20. Kumar Vaibhav, Pallavi Shrivastava, Andleeb Khan, Hayate Javed ,Rizwana
Tabassum, Md. Ejaz Ahmed, M. Badruzzaman Khan, Mohd. Moshahid Kha, Farah
Islam, Sayeed Ahmad, M. Saeed Siddiqui, Mohammed M. Safhi, Fakhrul Islam.
Azadirachta indica mitigates behavioral impairments, oxidative damage,
histological alterations and apoptosis in focal cerebral ischemia–reperfusion model
of rats. Neurological Sciences 2013 Aug; 34(8): 1321-30. DOI 10.1007/s10072-
012-1238-z. (Impact Factor – 1.41)
8
21. Rizwana Tabassum, Kumar Vaibhav, Pallavi Shrivastava, Andleeb Khan, Md. Ejaz
Ahmed, Hayate Javed, Farah Islam, Sayeed Ahmad, M. Saeed Siddiqui,
Mohammed M. Safhi, Fakhrul Islam. Centella asiatica attenuates the
neurobehavioral, neurochemical and histological changes in transient focal middle
cerebral artery occlusion rats. Neurological Sciences 2013 Jun; 34(6): 925-33. DOI
10.1007/s10072-012-1163-1. (Impact Factor – 1.41)
22. Pallavi Shrivastava, Kumar Vaibhav, Rizwana Tabassum, Andleeb Khan, Tauheed
Ishrat, Mohd Moshahid Khan, Ajmal Ahmad, Farah Islam, Mohammed M.
Safhi, Fakhrul Islam. Anti-apoptotic and Anti-inflammatory effect of Piperine on 6-
OHDA induced Parkinson's Rat model. Journal of Nutritional Biochemistry 2013
Apr; 24(4): 680-687; DOI:10.1016/j.jnutbio.2012.03.018. (Impact Factor – 4.29)
23. Ahmed ME, Khan MM, Javed H, Vaibhav K, Khan A, Tabassum R, Ashafaq M,
Islam F, Safhi MM, Islam F. Amelioration of cognitive impairment and
neurodegeneration by catechin hydrate in rat model of streptozotocin-induced
experimental dementia of Alzheimer's type. Neurochem Int. 2013 Mar; 62(4):492-
501.; 62(4): 492-501. (Impact Factor - 2.66)
24. Raza SS, Khan MM, Ahmad A, Ashafaq M, Wagner AP, Safhi MM, Islam F.
Neuroprotective effect of naringenin is mediated through suppression of NF-κB
signaling pathway in experimental stroke. Neuroscience 2013; 230: 157-171
(Impact Factor – 3.12)
25. S. M. Kumar, Mohammed M. Safhi. Isolation and screening of bioactive principle
from Chaetomorpha antennina against certain bacterial strains. Saudi
Pharmaceutical Journal 2013; 21: 119-121 (Impact Factor – 0.95)
26. S. M. Kumar, Mohammed M. Safhi, Aamena Jabeen, Kannadasan M.
Pharmaceutical aspects of Chitosan polymer “In Brief”. Research J. Pharm Tech
2013; 6(12): 1439 – 1442
27. Gupta Nakul, Sharma Ishan, Meetu Agarwal, Mohammed M Safhi, Chauhan
Prerna, Tarique Anwer, Gyas Khan. Antidiabetic activity of seed extract of
Caesalpinia crista Linn. in experimental animals. African Journal of Pharmacy
and Pharmacology 2013; 7(26): 1808-1813. (Impact Factor – 0.84)
28. Tarique Anwer, Manju Sharma, Gyas Khan, Muzaffar Iqbal, Md Sajid Ali, Md
Sarfaraz Alam, Mohammad M. Safhi, Nakul Gupta. Rhus coriaria ameliorates
insulin resistance in non-insulin dependent diabetes mellitus (NIDDM) rats. Acta
Poloniae Pharmaceutica-Drug Research 2013; 70(5): 861-867. (Impact Factor –
0.67)
29. Md. Sajid Ali, Md. Sarfaraz Alam, Nawazish Alam, Tarique Anwer, M. M. Safhi.
Accelerated Stability Testing of Clobetasol Propionate Loaded Nanoemulsion as per
ICH Guideline. Scientia Pharmaceutica 2013; 81: 1089–1100. DOI
10.3797/scipharm.1210-02
9
30. Anugeetha Thacheril Mohanan, Suba Venkatesan, Nithya Sermugapandian,
Mohammed Al-Safhi, Gyas Khan. Attenuating effect of Cilostazol against
vincristine – Induced neuropathic pain in mice. Journal of Pharmacy Research
2013; 6(5):579–582. (Impact Factor – 0.6)
31. Tamanna Jahangir, Mohammed M Safhi, Sarwat Sultana, Sayeed Ahmad. Pluchea
lanceolata protects against Benzo(a) pyrene induced renal toxicity and loss of DNA
integrity. Interdiscip Toxicol. 2013 March; 6(1): 47–54.
32. Gupta Nakul, Mohammed M Safhi, Jameel M. Y Suamily, Meetu Agarwal. Drug
prescribing patterns in children registered in the department of pediatric of Jizan
General Hospital of Jazan, KSA. International Journal of Pharmacy and
Pharmaceutical Sciences 2013; 5(4): 397-399. (Impact Factor – 1.59)
33. Md Sarfaraz Alam, Md Sajid Ali, Nawazish Alam, Massom Raza Siddiqui, Md
Shamim, M.M. Safhi. In Vivo study of clobetasol propionate loaded nanoemulsion
for topical application in psoriasis and atopical dermatitis. Drug Invention Today
2013; 5: 8-12.
34. Md. Intakhab Alam, Nawazish Alam, Md. Sajid Ali, Vikramjit Singh, Mohammed
M. Safhi, Md. Sarfaraz Alam, Tarique Anwer. Type, preparation and evaluation of
transdermal patch: a review. World Journal of Pharmacy and Pharmaceutical
Sciences 2013; 2(2): 2199-2233.
35. Mohammed M. Safhi. Spectrophotometric method for the estimation of Clinidipine
in bulk and pharmaceutical dosage forms. Oriental Journal of Chemistry 2013;
29(1): 131-134
36. Khan Hina, Gupta Nakul, Mohammed M Safhi, Meetu Agarwal, Khan Gyas,
Mohan Govind. Antiulcer activity of seed extracts of Gynocardia odorata Roxb. On
pylorus ligation and indomethacin induced gastric leision in albino rats.
International Journal of Development Research 2013; 3(5): 49-54.
37. Sharma Ishan, Gupta Nakul, Mohammed M Safhi, Meetu Agarwal, Chauhan
Prerna. Antipyretic activity of Caesalpinia crista Linn. seeds extract in
experimental animals. International Journal of Current Research May 2013; 5(5):
1202-1205
38. Mohammed M. Safhi, Makssod Ali, S. M. Sivakumar, Aamena Jabeen, Manoharaj
Y. N. Antibacterial studies of Catharanthus roseus of Jazan province against the
selected bacterial strains. Research J. Pharm Tech March 2013; 6(4): 403-405
39. Mohammed M. Safhi, Manoharaj Y. N. Development and validation of a rapid
stability indicating chromatographic determination of Clinidipine in bulk dosage
form. Research J. Pharm Tech March 2013; 6(3): 296-299
40. Mohammed M. Safhi. In vitro antibacterial screening of some commercially
available sodium flusidate ointment. Research J. Pharm Tech March 2013; 6(3):
289-291
11
41. Ahmad A, Khan MM, Raza SS, Javed H, Ashafaq M, Islam F, Safhi M.M, Islam F.
Ocimum sanctum attenuates oxidative damage and neurological deficits following
focal cerebral ischemia/reperfusion injury in rats. Neurol Sci. 2012 Dec;
33(6):1239-47. doi: 10.1007/s10072-012-0940-1. (Impact Factor – 1.41)
42. Khan A, Vaibhav K, Javed H, Khan MM, Tabassum R, Ahmed ME, Srivastava P,
Khuwaja G, Islam F, Siddiqui MS, Safhi MM, Islam F. Attenuation of Aβ-induced
neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and
oxidative stress. Mol Cell Biochem 2012 Oct; 369(1-2): 55–65. (Impact Factor -
2.33)
43. Ahmad A, Khan MM, Javed H, Raza SS, Ishrat T, Khan MB, Safhi M.M, Islam F.
Edaravone ameliorates oxidative stress associated cholinergic dysfunction and
limits apoptotic response following focal cerebral iscameia in rats. Molecular and
Cellular Biochemistry 2012 Aug; 367(1-2): 215-25. doi: 10.1007/s11010-012-
1335-6. (Impact Factor – 2.33)
44. Mohammad Ashafaq, Syed Shadab Raza, Mohd. Moshahid Khan, Ajmal Ahmad,
Hayate Javed, Md. Ejaz Ahmad, Rizwana Tabassum, Farah Islam, M. Saeed
Siddiqui, Mohammed M. Safhi, Fakhrul Islam. Catechin Hydrate Ameliorates
Redox Imbalance and Limits Inflammatory Response in Focal Cerebral Ischemia
Neurochemical Research 2012 Aug; 37(8): 1747-60. DOI 10.1007/s11064-012-
0786-1 (Impact Factor – 2.13)
45. Kumar Vaibhav, Pallavi Shrivastava, Hayate Javed, Andleeb Khan, Md. Ejaz
Ahmed, Rizwana Tabassum, Mohd. Moshahid Khan, Gulrana Khuwaja, Farah
Islam, M. Saeed Siddiqui, Mohammed M. Safhi, Fakhrul Islam. Piperine
suppresses cerebral ischemia–reperfusion-induced inflammation through the
repression of COX-2, NOS-2, and NF-jB in middle cerebral artery occlusion rat
model. Molecular and Cellular Biochemistry 2012 Aug; 367(1-2):73-84; DOI
10.1007/s11010-012-1321-z. (Impact Factor – 2.33)
46. H Javed, M M Khan, A Ahmad, K Vaibhav, M E Ahmad, A Khan, M Ashafaq, F
Islam, M S Siddiqui, M M Safhi. Rutin prevents cognitive impairments by
ameliorating oxidative stress and neuroinflammation in rat model of sporadic
dementia of Alzheimer type. Neuroscience 2012; 210: 340-52. (Impact Factor –
3.12)
47. Khan MM, Raza SS, Javed H, Ahmad A, Khan A, Safhi MM, Islam F. Rutin
Protects Dopaminergic Neurons from Oxidative Stress in an Animal Model of
Parkinson’s Disease. Neurotox Res 2012 Jul; 22(1): 1-15.doi: 10.1007/s12640-
011-9295-2. (Impact Factor – 2.87)
48. Mohammad Ashafaq, Mohd. Moshahid Khan, Syed Shadab Raza, Ajmal Ahmad,
Gulrana Khuwaja, Hayate Javed, Andleeb Khan, Farah Islam, M. Saeed Siddiqui,
Mohammed M. Safhi, Fakhrul Islam. S-allyl cysteine mitigates oxidative damage
and improves neurologic deficit in a rat model of focal cerebral ischemia. Nutrition
Research Feb 2012; 32: 133–143. (Impact Factor – 1.20)
49. Waquar ahsan, Mohammed M. Safhi, Nadeem Sidiqui, Shamama Javed, M.
Shamser Alam, Bismillah Azad, Javed Akhter. An insight into the new
11
anticonvulsant Agents. Current topics in Medicinal Chemistry, 2012, 12 1072-
1092. (Impact Factor – 4.47)
50. Tarique Anwer, Manju Sharma, K. K. Pillai, Gyas Khan and Mohammad M. Safhi.
Antihyperglycemic, antidyslipidemic and antioxidant activity of Rhus coriaria in
STZ-induced type 2 diabetic rats. African Journal of Pharmacy and
Pharmacology 2012; 6(41): 2851-2855. (Impact Factor – 0.84)
51. Mohammed M. Safhi, El-Hag HA. Agarose slide ELISA for diagnosis of HCV-AB
in rural areas. Journal of American Science 2012; 8(12): 865-871.
52. Sivakumar SM, Safhi MM, Kannadasan M, Sukumaran N. Vaccine adjuvants-
current status and prospects on controlled release adjuvancity. Saudi
Pharmaceutical Journal 2011; 19(4): 197-206. (Impact Factor – 0.95)
53. Alam MF, Safhi MM, Chopra AK. In vitro anti-malarial activity of aerial part of
Boenning hausenia albiflora. Env Conservation J 2011; 12(3): 7-11
54. Safhi MM. Novel spectrophotometric method for theestimation of Nisoldipine in
bulk and pharmaceutical dosages forms. Der Pharma Chemica 2011; 3(4): 275-
278.
55. Safhi MM and Anwer T. Comparative analysis of Withania somnifera and Rhus
coriaria on hyperglycemia and insulin sensitivity in type 2 diabetic rats. J Jazan
University 2011; 1 (1): 1-14.
56. Safhi MM. Formulation and in vitro evaluation of sustained release intra gastric
tablets of propranolol hydrochloride using natural polymer. J Pharmaceutical
Biomedical Sciences 2011; 10 (10): 1-6.
57. Nagaraj MY and Safhi MM. Rapid RP-HPLC method for estimation of nisoldipine
from tablet dosage form. Der Pharmacia Sinica. 2011; 2 (6): 122-126
58. El-Hag HA and Safhi MM. Antimalignancy activity of Bacillus thuringiensis
Serovar Dakota (H15) in vivo. World J Medical Sciences 2011; 6(1): 6-16.
59. Moni SS, Natarajapillai S, Safhi, MM. Immune augmentation of injectable PLGA-
Dextran (PLDEX) a double polymeric microspheres as an adjuvant for Hepatitis B
vaccine. World J Vaccine 2011, 1: 104-108.
60. Alam MF, Safhi MM, Chopra AK and Dua VK. Toxicological properties of several
medicinal plants from the Himalayas (India) against vectors of malaria, filariasis
and dengue. Tropical Biomedicine 2011; 28 (2): 343-350. (Impact Factor – 0.92)
61. Sachinkumar Vasantrao Patil, S. K. Sahoo, A. L. Behera, B. B. Barik, M. M. Safhi.
Consequences of Formulation Variables on Physicochemical Properties of Indinavir
Sulfate Microspheres. Jordan Journal of Pharmaceutical Sciences 01/2011;
4(3):251-260.
62. Dinda A, Biswal I, Das D, Si S, Kumar S, Barik BB, Safhi MM. Effect of
stabilizers and process parameters for budesonide loaded PLGA-nanoparticles.
International J Drug Delivery 2011; 3: 371-380.
12
63. Alam MF, Chopra AK, Safhi MM and Dua VK. Toxicity of Vernonia anthelmintica
Linn. (Asteracea) seeds against mosquitoes vectors. J Applied and Natural Science
2010; 2 (2): 190-193.
64. Raza SS, Khan MM, Ashafaq M, Ahmad A, Khuwaja G, Khan A, Siddiqui MS,
Safhi MM, Islam F. Silymarin protects neurons from oxidative stress associated
damages in focal cerebral ischemia: A behavioral, biochemical and
immunohistological study in Wistar rats. Journal of Neurological Sciences 2011
Oct; 309(1-2):45-54. (Impact Factor – 2.32)
65. Raza SS, Khan MM, Ahmad A, Ashafaq M, Khuwaja G, Tabassum R, Javed H,
Siddiqui MS, Safhi MM, Islam F. Hesperidin ameliorates functional and
histological outcome and reduces neuroinflammation in experimental stroke. Brain
Research 2011 Oct; 1420: 93-105. (Impact Factor – 2.46)
66. Ahmad A, Khan MM, Hoda MN, Raza SS, Khan MB, Javed H, Ishrat T, Ashafaq
M, Ahmad ME, Safhi MM, Islam F. Quercetin Protects Against Oxidative Stress
Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and
Reperfusion. Neurochemical Research 2011 Aug; 36(8):1360-71. (Impact Factor
– 2.13)
67. Javed H, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza
SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F. S-
allyl cysteine attenuates oxidative stress associated cognitive impairment and
neurodegeneration in mouse model of streptozotocin-induced experimental
dementia of Alzheimer's type. Brain Res. 2011; 10; 1389: 133-42. (Impact Factor
– 2.46)
68. Khuwaja G, Khan MM, Ishrat T, Raza SS, Khan A, Javed H, Khan MB, Safhi MM
and Islam F. Neuroprotective effects of curcumin on 6-hydroxydopamine-induced
Parkinsonism in rats: Behavioral, neurochemical and immunohisto-chemical
studies. Brain Res. 2011; 1368: 254-63. (Impact Factor – 2.46)
69. Khan MM, Hoda MN, Ishrat T, Ahmad A, Khan MB, Khuwaja G, Raza SS, Safhi
MM, Islam F. Amelioration of 1[methyl-4-phenyl-1,2,3,6-tetrahydropyridine-
inducedbehavioral dysfunction and oxidative stress by Pycnogenol in mouse model
of Parkinson's disease. Behav. Pharmacol. 2010; 21(5-6): 563-71. (Impact Factor
– 2.85)
70. Safhi MM, Rutherford C, Ledent C, Sands WA, Palmer TM. Priming of signal
transducer and activator of transcription proteins for cytokine-triggered
polyubiquitylation and degradation by the A 2A adenosine receptor. Molecular
Pharmacology 2010; Vol. 77 (6):968-78. (Impact Factor –4.53)
71. Safhi MM. Prevalence of Sickle Cell Disease in Population of Jazan Region, Saudi
Arabia. Ain Shams Science Bulletin 2009; Vol. 47: 21-27.