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CURRICULUM VITAE
David Randal Hessl, Ph.D.
Department of Psychiatry and Behavioral Sciences and
MIND Institute
University of California Davis Medical Center
2825 50th
Street
Sacramento, CA 95817
(916) 703-0249
EDUCATION
Ph.D. University of Washington. Seattle, WA (1997)
Major Area: Child Clinical Psychology
Minor Area: Developmental Psychology
Advisor: Geraldine Dawson, Ph.D.
M.S. University of Washington. Seattle, WA (1995)
Major Area: Child Clinical Psychology
B.A. University of California, Los Angeles. Los Angeles, CA (1989)
Major: Psychology
ADDITIONAL TRAINING
1996 – 1997 APA Accredited Internship. Lucile Salter Packard Children’s Hospital
at Stanford and The Children’s Health Council Consortium, Stanford and
Palo Alto, CA.
1997 - 1998 MacArthur Foundation Post-Doctoral Fellowship. Institute of Human
Development, University of California, Berkeley, CA.
ACADEMIC POSITIONS
2014 – present Professor of Clinical Psychiatry. Department of Psychiatry and
Behavioral Sciences and MIND Institute, University of California Davis
School of Medicine, Sacramento, CA.
2008 – 2014 Associate Professor of Clinical Psychiatry. Department of Psychiatry
and Behavioral Sciences and MIND Institute, University of California
Davis School of Medicine, Sacramento, CA.
David R. Hessl, PhD, 2
2006 – 2008 Assistant Professor of Clinical Psychiatry. Department of Psychiatry
and Behavioral Sciences and MIND Institute, University of California
Davis School of Medicine, Sacramento, CA.
2003 – 2006 Assistant Clinical Professor. Department of Psychiatry and Behavioral
Sciences and MIND Institute, University of California Davis School of
Medicine, Sacramento, CA.
2002 – 2003 Psychologist II. MIND Institute, University of California Davis School
of Medicine, Sacramento, CA.
1998 - 2001 Research and Clinical Psychologist. Behavioral Neurogenetics Research
Center, Division of Child Psychiatry, Stanford University School of
Medicine, Stanford, CA.
ACADEMIC AWARDS AND FELLOWSHIPS
1988 Honors in Psychology, University of California, Los Angeles
1991-1996 NIMH Graduate Student Research Fellowship, University of Washington
1994 Department of Psychology Dissertation Award, University of Washington
1997-1998 MacArthur Foundation Post-Doctoral Fellowship, Institute of Human
Development, University of California, Berkeley
2003 Joe P. Tupin Research Award, Department of Psychiatry, U.C. Davis
2004 Co-Recipient, National Fragile X Foundation Hagerman Award, for
contribution to the discovery of Fragile X-Associated Tremor/Ataxia
Syndrome
2006 U.C. Davis Imaging Research Center Award
2007-2008 MIND Institute Pilot Research Grant Award
2008 U.C. Davis Academic Senate Research Travel Award
2008 U.C. Davis finalist – John Merck Scholars Program, Biology of
Developmental Disabilities in Children
2009 Dean’s Team Award for Excellence, U.C. Davis School of Medicine
2012 Jarrett Cole Clinical Award, National Fragile X Foundation, for
“Dedicated Service to Families in the Worldwide Fragile X Community”
COMMITTEES AND SERVICE
2004 - Member, Human Development Graduate Group, UC Davis
2009 - Scientific and Clinical Advisory Board, National Fragile X Foundation
2008 - 2011 Member, Admissions Committee, U.C. Davis School of Medicine
2011 - 2014 Member, Committee on Student Progress, U.C. Davis School of Medicine
2008 - 2010 Co-Chair, Interview Subcommittee, Admissions Committee, U.C. Davis
School of Medicine
David R. Hessl, PhD, 3
2009 University of California, Davis Health System Centennial Event Panelist,
Cornell Club, New York, NY and Capitol Visitor Center, Washington, DC
2010 - 2012 Member, Town Hall Committee, MIND Institute, U.C. Davis
2010 - 2011 Member, Research IV Planning Committee, U.C. Davis School of
Medicine
2011 - 2014 Member, Committee on Student Progress, U.C. Davis School of Medicine
2013 - Specialty Advisor, UC Davis School of Medicine
2014 - 2015 Member, Committee on Research, UC Davis School of Medicine
2014 - Member, Clinical Trials Committee, Fragile X Clinical and Research
Consortium
2015 - Member, Neuroscience Graduate Group, UC Davis
2015 Special Emphasis Panel, Centers for Disease Control and Prevention,
“Using Longitudinal Data to Characterize the Natural History of Fragile X
Syndrome to Improve Services and Outcomes”
2014 - Faculty Mentor, MIND Institute International Training Program in
Neurodevelopmental Disorders (ITPND), UC Davis
2016 Ad Hoc Reviewer, Board of Scientific Counselors, National Institute of
Mental Health
2016 - Faculty Welfare Committee, UC Davis
2016 - Child and Family Care Administrative Advisory Committee, UC Davis
PANELS AND ADVISORY POSITIONS
Member, Adolescents and Adults Projects Team, National Fragile X Foundation
Reviewer, Social Sciences and Humanities Research Council of Canada
Member, NIH Fragile X Research Coordinating Group
Member, Fragile X Clinical & Research Consortium Executive Council
Advisory Panelist, NICHD Outcome Measures for Clinical Trials with Children with Fragile X
Syndrome
Invited Participant, NIH Research Plan for Fragile X Syndrome and Associated Disorders (2008)
Panelist, “How to Develop an Interdisciplinary Program of Research”, NIH Interdisciplinary
Training Conference on Developmental Disabilities, Annapolis, MD
Invited Participant, NIH Research Plan for Fragile X Syndrome and Associated Disorders (2012)
Clinical Trials Consultant, Hoffman LaRoche
Clinical Trials Consultant, Novartis
Clinical Trials Consultant, Seaside Therapeutics
Invited Expert Panelist, “The Future of Fragile X: Center for Disease Control Public Health
Research Agenda”, Atlanta (2014)
COMMUNITY SERVICE
“A Conversation Between a Researcher and a Parent of a Child with Autism”, Access To Care,
Bayside Church, Roseville, CA
David R. Hessl, PhD, 4
Donation of an in-home evaluation of a child with fragile X syndrome in Iowa, to benefit the
National Fragile X Foundation, 2007
Donation of an in-home evaluation of two children with fragile X syndrome in Missouri, to
benefit the National Fragile X Foundation, 2008
Donation of an in-home evaluation a child with fragile X syndrome in Mississippi, to benefit the
National Fragile X Foundation, 2011
Provided consultation in an autism clinic, in association with the First Annual Autism
Conference, Dubai, United Arab Emirates, 2005
ACADEMIC PROFESSIONAL SERVICE
Editorial Board Member – Journal of Neurodevelopmental Disorders
Co-Editor, Special Issue on Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) – The Clinical
Neuropsychologist (2016)
Ad Hoc Reviewer
Acta Psychiatrica Scandinavica
American Journal on Intellectual and Developmental Disabilities
American Journal of Medical Genetics Part B:Neuropsychiatric Genetics
American Journal of Psychiatry
Annals of Neurology
Autism Research
Behavior Genetics
Behavioral Brain Research
Brain and Cognition
Clinical Genetics
Genes, Brain and Behavior
Biological Psychiatry
Child Development
Development and Psychopathology
International Journal of Psychophysiology
Journal of Autism and Developmental Disorders
Journal of Child Psychology and Psychiatry
Journal of Intellectual Disability Research
Neuropsychology
Pediatrics
Psychoneuroendocrinology
The Clinical Neuropsychologist
PROFESSIONAL AFFILIATIONS
American Psychological Association
David R. Hessl, PhD, 5
Division 33 (Intellectual and Developmental Disabilities) – American Psychological Association
LICENSURE
Licensed Psychologist, State of California, #16690, 2000 - present
MENTORING AND TEACHING
Dissertation Chair for Alyssa Chavez, Department of Human Development, U.C. Davis
Dissertation Co-Chair for Susannah Cohen, Department of Human Development, U.C. Davis
Mentor to Paula Wadell-Weinstein, M.D., Psychiatry Resident, U.C. Davis School of Medicine
Mentor to Lisa Cordeiro, Department of Human Development, U.C. Davis
Mentor to Laurie Vismara, Ph.D., Autism Research Training Program, MIND Institute
Mentor to Lisa Litt, Ph.D., Autism Research Training Program, MIND Institute
Mentor to Andrea Schneider, Ph.D., Post-Doctoral Fellow, MIND Institute
Co-Facilitator, Doctoring, U.C. Davis School of Medicine
Faculty Member, Autism Research Training Program (PIs David Amaral and Sally Rogers)
Mentor to Stephanie Sansone (Maltas), Department of Human Development, U.C. Davis, National
Science Foundation Graduate Research Fellowship Program, “The Fragile X Premutation and
Differential Susceptibility to Immune Dysfunction: Examination of a Possible Gene-
Environment Interaction with Chronic Stress”
Psy.D. Clinical Internship Supervisor to Amy Gaines
Psy.D. Clinical Internship Supervisor to Corrisa Jacomini
Dissertation Committee Chair, Stephanie Sansone, Human Development, UC Davis
Dissertation Committee Member, Emily Halkett, Psychology, UC Davis
Mentor to Rebecca Shields, Human Development graduate student, UC Davis
Dissertation Committee Member, Abbie Poppa, Neuroscience Graduate Group, UC Davis
Mentor, International Training Program in Neurodevelopmental Disorders, Ying Han (China)
Mentor, International Training Program in Neurodevelopmental Disorders, Ariadna Ramírez Mallafré
(Spain)
Chair, Master’s Thesis Committee, Rebecca Shields, Human Development, UC Davis
GRANTS AND OTHER SUPPORT
Active NICHD – 1R01HD076189
A Cognitive Test Battery for Intellectual Disabilities
Role: PI
Amount: $3,145,326 total for 5 years
Active The John Merck Fund: Developmental Disabilities Translational Research
Grant
Cognitive Training for Fragile X Syndrome
Role: PI
David R. Hessl, PhD, 6
Amount: $1,000,000 total for 4 years
Active NIMH - 2R01MH078041-06
Trajectories and Markers of Neurodegeneration in Fragile X Premutation
Carriers
Role: Co-Equal PI with S. Rivera
Amount: $2,970,846 for 5 years
Active Centers for Disease Control
Fragile X Clinical Research Consortium
Role: UC Davis Site PI
2011-2015 Department of Defense – 10600754
Treatment of Fragile X Syndrome with a Neuroactive Steroid
Role: Co-PI
Amount: $3,018,652 total for 4 years
Active NICHD R01HD036071
Genotype-Phenotype Relationships in Fragile X Families
Role: Co-Investigator
Amount: $2,908,668 for 5 years
2011-2014 HRSA
Controlled Trial of Sertraline in Young Children with Fragile X Syndrome
Role: Co-Investigator
Amount: $857,090
2013-2014 National Fragile X Foundation
Extending Autism Behavioral Intervention to Young Children with Fragile
X Syndrome
Role: PI
Amount: $50,000 for 1 year
2013 MIND Institute Intellectual Disabilities Research Center (IDDRC) Pilot
Grant
Event-related Oscillatory Brain Activity as Outcome Measure for Targeted
Treatment Trials in Fragile X Syndrome
Role: Co-Investigator
Amount: $30,000 for 1 year
2007-2013 NIMH - R01MH078041
Limbic System Function in Carriers of the Fragile X Premutation
Role: PI
Amount: $1,558,710 total for 5 years
2011-2013 NIMH - 3R01MH078041-04S1 (Competitive Revision).
Limbic System Function in Carriers of the Fragile X Premutation
David R. Hessl, PhD, 7
Role: PI
Amount: $766,250 total for 2 years
2008-2013 NICHD - R01HD059967-01A2
An Open Resource for Autism iPSCs and Their Derivatives
PI: Charles Schwartz, UCI
Role: Co-Investigator
Amount: $501,923
2007-2012 NIA - RL11RL1AG032115-01
NeuroTherapeutics Research Consortium
Characterization and Treatment of CNS Abnormalities in Premutation
Carriers
Overall PI: Paul Hagerman; Component PI: Randi Hagerman
Role: Co-Investigator
Amount: $6,711,049 total for 5 years
2010-2011 National Fragile X Foundation
A Double Blind Randomized Controlled Cross Over Trial of Minocycline
in Children with Fragile X Syndrome
PI: Randi Hagerman
Role: Co-PI
Amount: $75,000
2009-2011 MIND Institute Pilot Research Grant
Candidate Gene Association Analysis of the FMR1 Pathway in Idiopathic
Autism Spectrum Disorders
PI: Simeon Boyd
Role: Co-Investigator
Amount: $50,000
2009 Seaside Therapeutics
A Double-Blind, Placebo-Controlled, Crossover, Flexible-Dose
Evaluation of the Efficacy, Safety, and Tolerability of STX209 in the
Treatment of Irritability in Subjects with Fragile X Syndrome
PI: Randi Hagerman
Role: Co-Investigator
Amount: $10,244 per patient
Completed Hoffman-LaRoche
A randomized, double-blind, placebo-controlled, pharmacokinetic, safety
and tolerability, and exploratory efficacy and pharmacodynamic effects
study of RO4917523 in adult patients with fragile X syndrome
Role: Co-Investigator
Amount: $337,158
David R. Hessl, PhD, 8
2010 FRAXA Research Foundation
Aberrant Behavior Checklist in Fragile X Syndrome
Role: PI
Amount: $10,000
2007-2009 NICHD - R21MH080025
Amygdala Function in Children and Adolescents with Fragile X
Syndrome
PI: Susan Rivera
Role: Co-Investigator
Amount: $417,000 total for 2 years
2009-2010 NCRR/NICHD
A Toolbox of Outcome Measures for Targeted Treatment Trials in
Children – UC Davis Clinical and Translational Science Center
Supplement
PI: Lars Berglund
Role: Co-Investigator
Amount: $350,380
2005-2010 NIMH - 1K23MH77554: Patient-Oriented Career Development Research
Grant
Genetics and Physiology of Social Anxiety in Fragile X
Role: PI
Amount: $771,837 total for 5 years
2008-2009 Neuropharm, Ltd. - NPL-2009-2-FEN-001
An Open Label Exploratory Study to Investigate the Effect of Fenobam
Monohydrate (Fenobam 50 mg – 150 mg single dose) on Prepulse
Inhibition Tests and Continuous Performance Tasks, in Adults with
Fragile X Syndrome
Role: Co-PI
Amount: $53,835 for one year
2007-2008 MIND Institute Pilot Research Grant
Sensorimotor Gating in Idiopathic Autism and Autism in Fragile X
Syndrome
Role: PI
Amount: $50,000 for 1 year
2007-2008 MIND Institute Pilot Research Grant
Y Chromosome Gene Expression in Autism Spectrum Disorders
PI: Robin Hansen
Role: Co-Investigator
Amount: $24,920 for 1 year
David R. Hessl, PhD, 9
2006 -2007 Children’s Miracle Network
Autistic Spectrum Disorders and Behavioral Problems in Male Children
with Sex Chromosome Aneuploidy
Role: PI
Amount: $60,000 total for 2 years
2005 - 2006 National Fragile X Foundation
Hyperarousal and Aggressive Behavior in Fragile X Syndrome
Role: PI
Amount: $30,000 for 1 year
2002 - 2005 NIH Grant #HD36071: Genotype-Phenotype Relationships in Fragile X
Families
PI: Randi Hagerman, M.D.
Role: Psychologist, 40% support
2004 – 2005 NIH Grant # 1 R01 NS044299-01: Action Tremor and Dementia in Male
Carriers of Fragile X
PI: Jim Grigsby, Ph.D.
Role: Psychologist, 10% support
2003 – 2004 Joe P. Tupin Award – Department of Psychiatry, U.C. Davis: Genetic,
Physiological, and Neuroendocrine Correlates of Anxiety in Fragile X
Syndrome
Amount of award: $35,000
Role: P.I.
PEER REVIEWED JOURNAL ARTICLES
1. Tartaglia NR, Wilson R, Miller JS, Rafalko J, Cordeiro L, Davis S, Hessl D, Ross J. Autism
Spectrum Disorder in Males with Sex Chromosome Aneuploidy (2017). Journal of
Developmental and Behavioral Pediatrics, 38(3):197-207. PMID: 28333849.
2. Wang JY, Hessl D, Hagerman RJ, Simon TJ, Tassone F, Ferrer E, Rivera SM. Abnormal
trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation.
Neurobiology of Aging (55), 11-19. PMID: 28391068.
3. Budimirovic DB, Berry-Kravis E, Erickson CA, Hall SS, Hessl D, Reiss AL, King MK,
Abbeduto L, & Kaufmann WE (In press). Updated report on tools to measure outcomes of
clinical trials in fragile X syndrome. Journal of Neurodevelopmental Disorders.
4. Greiss-Hess L, Fitzpatrick SE, Nguyen DV, Chen Y, Gaul KN, Schneider A, Lemons-Chitwood
K, Eldeeb M, Polussa J, Hessl D, Rivera S, & Hagerman RJ (2016). A randomized, double-
blind, placebo-controlled trial of low-dose sertraline in young children with fragile X
syndrome. Journal of Developmental and Behavioral Pediatrics.
5. Hessl D, Sansone S, Berry-Kravis E, Riley K, Widaman K, Abbeduto L, Schneider A, Coleman
J, Oaklander D, Rhodes K, & Gershon R (2016). The NIH Toolbox Cognitive Battery for
intellectual disabilities: Three preliminary studies and future directions. Journal of
Neurodevelopmental Disorders 8(1), 35.
David R. Hessl, PhD, 10
6. Lozano R, Saito N, Reed D, Eldeeb M, Schneider A, Hessl D, Tassone F, Beckett L, &
Hagerman RJ (2016). Aging in fragile X premutation carriers. The Cerebellum.
doi:10.1007/s12311-016-0805-x.
7. Gossett A, Sansone S, Schneider A, Johnston C, Hagerman RJ, Tassone F, Rivera SM, Seritan
A, & Hessl D (2016). Psychiatric disorders among women with the fragile X premutation
without children affected by fragile X syndrome. American Journal of Medical Genetics Part
B: Neuropsychiatric Genetics.
8. Hessl D & Grigsby (2016). Fragile X-associated tremor/ataxia syndrome: Another phenotype of
the FMR1 gene. Special Issue, Frontiers in Clinical Neuropsychology: Fragile X-Associated
Tremor-Ataxia Syndrome. The Clinical Neuropsychologist 30(6), 810-814.
9. Schneider A, Johnston C, Tassone F, Sansone S, Hagerman RJ, Ferrer E, Rivera SM, & Hessl D
(2016). Broad autism spectrum and obsessive-compulsive symptoms in adults with the fragile
X premutation. Special Issue, Frontiers in Clinical Neuropsychology: Fragile X-Associated
Tremor-Ataxia Syndrome. The Clinical Neuropsychologist 30(6), 929-943.
10. Wang JY, Ngo MM, Hessl D, Hagerman RJ, & Rivera SM (2016). Robust machine learning-
based correction on automatic segmentation of the cerebellum and brainstem. PLoS ONE
11(5): e0156123.
11. Cordeiro L, Abucayan F, Hagerman RJ, Tassone F, & Hessl D (2015). Anxiety disorders in
premutation carriers: Preliminary characterization of probands and non-probands. Intractable
and Rare Diseases Research 4(3), 123-130.
12. Au J, Berkowitz-Sutherland L, Schneider A, Schweitzer JB, Hessl D, & Hagerman RJ (2014). A
feasibility trial of Cogmed working memory training in fragile X syndrome. Journal of
Pediatric Genetics 3(3).
13. Sansone SM, Schneider A, Bickel E, Berry-Kravis E, Prescott C, & Hessl D (2014). Improving
IQ measurement in intellectual disabilities using true deviation from population norms.
Journal of Neurodevelopmental Disorders 6(16), 1-14.
14. McCormick C, Hessl D, Macari SL, Ozonoff S, Green C, Rogers SJ (2014). Electrodermal and
behavioral responses of children with autism spectrum disorders to sensory and repetitive
stimuli. Autism Research 7(4), 468-480.
15. Lozano R, Summers S, Lozano C, Mu Y, Hessl D, Nguyen D, Tassone F, & Hagerman RJ
(2014). Association between macroorchidism and intelligence in FMR1 premutation carriers.
American Journal of Medical Genetics 164A(9), 2206-2211.
16. Brick DJ, Nethercott HE, Montesano S, Banuelos MG, Stover AE, Schutte SS, O’Dowd DK,
Hagerman RJ, Ono M, Hessl D, Tassone F, & Schwartz PH (2014). The autism spectrum
disorders stem cell resource at CHOC Children’s Hospital of Orange County: Implications for
disease modeling and drug discovery. Stem Cells Translational Medicine 3, 1275-1286.
17. Ballinger EC, Cordeiro L, Chavez AD, Hagerman RJ, & Hessl D (2014). Emotion potentiated
startle in fragile X syndrome. Journal of Autism and Developmental Disabilities 44(10),
2536-2546. PMID: 4167929.
18. Loesch DZ, Bui MQ, Hammersley E, Schneider A, Storey E, Stimpson P, Burgess T, Francis D,
Slater H, Tassone F, Hagerman RJ, & Hessl D (2014). Psychological status in female carriers
of premutation FMR1 allele showing a complex relationship with the size of CGG expansion.
Clinical Genetics 87(2), 173-178.
19. Wheeler A, Raspa M, Bann C, Bishop E, Hessl D, Sacco P, & Bailey D (2014). Anxiety,
attention problems, hyperactivity, and the Aberrant Behavior Checklist in fragile X syndrome.
American Journal of Medical Genetics Part A, 164A, 141-155.
David R. Hessl, PhD, 11
20. Cohen S, Masyn K, Mastergeorge A, & Hessl D (2015). Psychophysiological responses to
emotional stimuli in children and adolescents with autism and fragile X syndrome. Journal of
Clinical Child and Adolescent Psychology 44(2), 250-263. PMID: 24156344.
21. Basuta K, Lozano R, Schneider A, Yrigollen CM, Hessl D, Hagerman RJ, & Tassone F (2014).
A family with two females compound heterozygous for the FMR1 premutation. Clinical
Genetics 85(5), 458-463. PMID: 23786467.
22. Schneider A, Leigh MJ, Adams P, Nanakul R, Chechi T, Olichney J, Hagerman RJ, & Hessl D
(2013). Electrocortical changes associated with minocycline treatment in fragile X syndrome.
Journal of Psychopharmacology, 27(10), 965-963. PMID: 23981511.
23. Wang JY, Hessl D, Schneider A, Tassone F, Hagerman RJ, & Rivera SM (2013). Fragile X-
associated tremor/ataxia syndrome: Influence of the FMR1 gene on motor fiber tracts in males
with normal and premutation alleles. JAMA Neurology 70(8), 1022-1029. PMID: 23753897.
24. Berry-Kravis E, Hessl D, Abbeduto L, Reiss AL, Beckel-Michener A, & Urv TK (2013).
Outcome measures for clinical trials in fragile X syndrome. Journal of Developmental and
Behavioral Pediatrics, 34(7) 508-522. PMID: 24042082.
25. Russo-Ponsaran N, Yesensky J, Hessl D, & Berry-Kravis E (2014). Feasibility, reproducibility,
and clinical validity of the Pediatric Anxiety Rating Scale – Revised for fragile X syndrome.
American Journal on Intellectual and Developmental Disabilities 119(1), 1-16.
26. Schneider A, Seritan A, Tassone F, Rivera S, Hagerman RJ, & Hessl D (2013). Psychiatric
features in high-functioning adult brothers with fragile X spectrum disorders. The Primary
Care Companion for CNS Disorders, 15(2).
27. Wadell PM, Hagerman RJ, & Hessl D (2013). Fragile X syndrome: Psychiatric manifestations,
assessment, and emerging therapies. Current Psychiatry Reviews, 9: 53-58.
28. Leigh MJS, Nguyen DV, Mu Y, Winarni TI, Schneider A, Chechi T, Polussa J, Doucet P,
Tassone F, Rivera SM, Hessl D, & Hagerman RJ (2013). A randomized double-blind,
placebo-controlled trial of minocycline in children and adolescents with fragile X syndrome.
Journal of Developmental and Behavioral Pediatrics, 34(3), 147-155. PMID: 23572165
29. Kim S, Burris J, Bassal F, Koldewyn K, Chattarji S, Tassone F, Hessl D, & Rivera SM (2012).
Fear-specific amygdala function in children and adolescents on the fragile X spectrum: A
dosage response of the FMR1 gene. Cerebral Cortex 24(3), 600-613. PMID: 23146966
30. Wang JM, Koldewyn K, Hashimoto R, Schneider A, Li L, Tassone F, Cheung C, Hagerman PJ,
Hessl D, & Rivera SM (2012). Male carriers of the FMR1 premutation show altered
hippocampal-prefrontal function during memory encoding. Frontiers in Human Neuroscience,
2(6): 297. PMID: 23115550
31. Wang JY, Hessl D, Iwahashi C, Cheung K, Schneider A, Hagerman RJ, Hagerman PJ, & Rivera
SM (2012). Influence of the fragile X mental retardation (FMR1) gene on the brain and
working memory in men with normal FMR1 alleles. Neuroimage, 65: 288-298. PMID:
23063447
32. Berry-Kravis EM, Hessl D, Rathmell B, Zarevics P, Cherubini M, Walton-Bowen K, Mu Y,
Nguyen DM, Gonzalez-Heydrich J, Wang PP, Carpenter RL, Bear MF, & Hagerman RJ
(2012). Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults
with fragile X syndrome: A randomized, controlled, Phase 2 trial. Science Translational
Medicine, 4(152): 152ra127. PMID: 22993294
33. Hamlin AA, Sukharev D, Campos L, Mu Y, Tassone F, Hessl D, Nguyen DV, Loesch D, &
Hagerman RJ (2012). Hypertension in FMR1 premutation males with and without fragile X-
David R. Hessl, PhD, 12
associated tremor /ataxia syndrome (FXTAS). American Journal of Medical Genetics: Part A.
158A(6), 1304-1309. PMID: 22528549
34. Knox A, Schneider A, Abucayan F, Hervey C, Tran C, Hessl D & Berry-Kravis E (2012).
Feasibility, Reliability, and Clinical Validity of the Tests of Attentional Performance for
Children (KiTAP) in Fragile X Syndrome (FXS). Journal of Neurodevelopmental Disorders
4: 2. PMID: 22958782
35. Chonchaiya W, Au J, Schneider A, Hessl D, Harris SW, Laird M, Nguyen DV, Mu Y, Tassone
F, Hagerman RJ (2011). Increased prevalence of seizures in boys who were probands with
the FMR1 premutation and co-morbid autism spectrum disorder. Human Genetics 131(4),
581-589. PMID: 22001913
36. Sansone SM, Widaman KF, Hall SS, Reiss AL, Lightbody A, Kaufmann WE, Berry-Kravis E,
Lachiewicz A, Brown EC, & Hessl D (2011). Psychometric study of the Aberrant Behavior
Checklist in fragile X syndrome and implications for targeted treatment. Journal of Autism
and Developmental Disorders 42(7), 1377-1392. PMID: 21972117
37. Wang JY, Hessl D, Hagerman RJ, Tassone F, & Rivera SM (2012). Age-dependent structural
connectivity effects in fragile X premutation. Archives of Neurology, 69(4), 482-489. PMID:
22491193
38. Selmeczy D, Koldewyn K, Wang JM, Lee A, Harvey D, Hessl D, Tassone F, Adams P,
Hagerman RJ, Hagerman PJ, & Rivera SM (2011). Investigation of amygdala volume in men
with the fragile X premutation. Brain Imaging and Behavior, 5(4), 285-294. PMID: 21786216
39. Hessl D, Wang JM, Schneider A, Koldewyn K, Le L, Iwahashi C, Tassone F, Hagerman PJ, &
Rivera SM (2011). Deficient FMRP underlies amygdala dysfunction in carriers of the fragile
X premutation. Biological Psychiatry, 70(9), 859-865. PMID: 21783174
40. Farzin F, Scaggs F, Hervey C, Berry-Kravis E, & Hessl D (2011). Reliability of eye tracking
and pupillometry measures in individuals with fragile X syndrome. Journal of Autism and
Developmental Disorders, 41(11), 1515-1522. PMID: 21267642
41. Cordeiro, L., Ballinger, E., Hagerman RJ, & Hessl D (2011). Clinical assessment of DSM-IV
anxiety disorders in fragile X syndrome: Prevalence and characterization. Journal of
Neurodevelopmental Disorders 3, 57-67. PMID: 21475730
42. Schneider, A., Ballinger, E., Chavez, A., Tassone F, Hagerman RJ, & Hessl D (2010). Prepulse
inhibition in patients with fragile X-associated tremor ataxia syndrome. Neurobiology of
Aging, 33(6), 1045-1053. PMID: 20961665
43. Chonchaiya, W., Tassone F, Ashwood, P., Hessl D, Schneider, A., Campos, L., Nguyen, D.V.,
Hagerman RJ (2010). Autoimmune disease in mothers with the FMR1 premutation is
associated with seizures in their children with fragile X syndrome. Human Genetics, 30(6),
544-551. PMID: 20809278
44. Yuhas J, Cordeiro L, Tassone F, Ballinger L, Schneider A, Long JM, Ornitz EM, & Hessl D
(2010). Sensorimotor gating in idiopathic autism and autism associated with fragile X
syndrome. Journal of Autism and Developmental Disorders, 41(2), 248-253. PMID:
20521090
45. Utari A, Adams E, Berry-Kravis E, Chavez A, Scaggs F, Ngotran L, Boyd A, Hessl D, Gane L,
Tassone F, Tartaglia N, Leehey M & Hagerman RJ (2010). Aging in fragile X syndrome.
Journal of Neurodevelopmental Disorders, 2(2), 70-76. PMID: 20585378
46. Ashwood P, Nguyen DV, Hessl D, Hagerman RJ, & Tassone F (2010). Plasma cytokine profiles
in Fragile X subjects: Is there a role for cytokines in the pathogenesis? Brain, Behavior, and
Immunity, 24(6), 898-902.
David R. Hessl, PhD, 13
47. Schneider A, Hagerman RJ & Hessl D (2009). Fragile X syndrome: From genes to cognition.
Special issue: Cognitive Profiles in Sex Chromosome Disorders. Developmental
Disabilities Research Reviews, 15(4), 333-342. PMID: 20014363
48. Bourgeois JA, Seritan AL, Casillas EM, Hessl D, Schneider A, Yang Y, Kaur I, Cogswell JB,
Nguyen DV, & Hagerman RJ (2011). Lifetime prevalence of mood and anxiety disorders in
fragile X premutation carriers. Journal of Clinical Psychiatry, 72, 175-182. PMID:
20816038
49. Adams PE, Adams JS, Nguyen DV, Hessl D, Brunberg JA, Tassone F, Zhang W, Koldewyn K,
Rivera SM, Grigsby J, Zhang L, DeCarli C, Hagerman PJ, & Hagerman RJ (2010).
Psychological symptoms correlate with reduced hippocampal volume in fragile X
premutation carriers. American Journal of Medical Genetics: Neuropsychiatric Genetics 3,
775-785.
50. Chonchaiya W, Utari A, Pereira GM, Tassone F, Hessl D, & Hagerman RJ (2009). Broad
clinical involvement in a family affected by the fragile X premutation. Journal of
Developmental and Behavioral Pediatrics, 30, 544-551.
51. Bourgeois J, Coffey S, Rivera SM, Hessl D, Gane LW, Tassone F, Greco C, Finucane B, Nelson
L, Berry-Kravis E, Grigsby J, Hagerman PJ & Hagerman RJ (2009). The family of fragile
X premutation disorders: Expanding the psychiatric perspective. Journal of Clinical
Psychiatry 70(6) 852-862.
52. Farzin F, Rivera SM, & Hessl D (2009). Face processing in individuals with fragile X
syndrome: An eye tracking study. Journal of Autism and Developmental Disorders, 39(6)
946-952. PMID: 2684976
53. Solomon M, Hessl D, Chiu S, Olsen E, & Hendren R (2009). Towards a neurodevelopmental
model of clinical case formulation. Psychiatric Clinics of North America, 32(1) 199-211.
54. Zingerevich C, Greiss-Hess L, Lemons-Chitwood K, Harris S, Hessl D, & Hagerman RJ (2009).
Motor abilities of children with fragile X syndrome. Journal of Intellectual Disabilities
Research, 53(1), 11-18.
55. Berry-Kravis E, Hessl D, Coffey S, Hervey C, Schneider A, Yuhas J, Hutchinson J, Snape M,
Tranfaglia M, Nguyen DV, & Hagerman RJ (2009). A pilot open-label singe-dose trial of
Fenobam in adults with fragile X syndrome. Journal of Medical Genetics, 46(4) 266-271.
PMID: 19126569
56. Hagerman RJ, Berry-Kravis E, Ono MY, Tartaglia N, Lachiewicz A, Kronk R, Delahunty C,
Kaufmann WE, Hessl D, Visootsak J, Picker J, Gane LW, & Tranfaglia M (2009).
Advances in the treatment of fragile X syndrome. Pediatrics, 123(1), 378-390.
57. Hessl D, Nguyen DV, Green C, Chavez A, Tassone F, Hagerman RJ, Senturk D, Schneider A,
Lightbody A, Reiss AL & Hall S (2009). A solution to limitations of cognitive testing in
children with intellectual disabilities: The case of fragile X syndrome. Journal of
Neurodevelopmental Disorders, 1, 33-45. PMID: 19865612
58. Hessl D, Cordeiro L, Yuhas J, Campbell A, Ornitz E, Berry-Kravis E, Chruscinski E, Hervey C,
Long JM, & Hagerman RJ (2009). Prepulse inhibition in fragile X syndrome: Feasibility,
reliability and implications for treatment. American Journal of Medical Genetics Part B:
Neuropsychiatric Genetics, 150B(4) 545-553.
59. Harris SW, Hessl D, Bacalman S, Goodlin-Jones B, Ferranti J, Herman K, Tassone F, Barbato I,
Hagerman PJ, & Hagerman RJ (2008) Autism profiles of males with fragile X syndrome.
American Journal of Intellectual and Developmental Disabilities 113(6), 427-438.
David R. Hessl, PhD, 14
60. Hagerman RJ, Berry-Kravis E, Hessl D, Coffey S, Schneider A, Nguyen DV, Hervey C,
Hutchinson J, & Snape M (2008). Trial of fenobam, an mGluR5 antagonist, in adults with
Fragile X Syndrome. Journal of Intellectual Disabilities Research, 52(10), 814.
61. Brouwer JR, Severijnen E, de Jong FH, Hessl D, Hagerman RJ, Oostra BA, & Willemsen R
(2008). Altered hypothalamus-pituitary-adrenal gland axis regulation in the expanded
CGG-repeat mouse model for fragile X-associated tremor/ataxia syndrome.
Psychoneuroendocrinology, 33, 863-873.
62. García-Nonell C, Ratera ER, Harris S, Hessl D, Ono M, Tartaglia N, Marvin E, Tassone F, &
Hagerman RJ (2008). Secondary medical diagnosis in fragile X syndrome with and without
autism spectrum disorder. American Journal of Medical Genetics, 146A(15), 1911-1916.
63. Koldewyn K, Hessl D, Adams J, Tassone F, Hagerman RJ, Hagerman PJ, & Rivera S (2008).
Reduced hippocampal activation during recall is associated with elevated FMR1 mRNA and
psychiatric symptoms in men with the fragile X premutation. Brain Imaging and Behavior,
2, 105-116.
64. Brega AG, Goodrich G, Bennett RE, Hessl D, Engle K, Leehey MA, Bounds LS, Paulich MJ,
Hagerman RJ, Hagerman PJ, Cogswell JB, Tassone F, Reynolds A, Kooken R, Kenny M, &
Grigsby J (2008). The primary cognitive deficit among males with fragile X-associated
tremor/ataxia syndrome (FXTAS) is a dysexecutive syndrome. Journal of Clinical and
Experimental Neuropsychology, 15, 1-17.
65. Soontarapornchai K, Maselli R, Fenton-Ferrell G, Tassone F Hagerman PJ, Hessl D, &
Hagerman RJ (2008). Abnormal nerve conduction features in fragile X premutation
carriers. Archives of Neurology 65(4), 469-498.
66. Grigsby J, Brega AG, Engle K, Leehey MA, Hagerman RJ, Tassone F, Hessl D, Hagerman PJ,
Cogswell JB, Bennett RE, Cook K, Hall DA, Bounds LS, Paulich MJ & Reynolds A (2008).
Cognitive profile of fragile X premutation carriers with and without fragile X-associated
tremor/ataxia syndrome. Neuropsychology 22(1), 48-60.
67. Hessl D, Tassone F, Cordeiro L, Koldewyn K, McCormick C, Green C, Wegelin J, Yuhas J, &
Hagerman RJ (2008). Aggression and stereotypic behavior in males with fragile X
syndrome: Moderating secondary genes in a “single gene” disorder. Journal of Autism and
Developmental Disorders 38(1), 184-189.
68. Bourgeois JA, Cogswell JB, Hessl D, Zhang L, Ono MY, Tassone F, Farzin F & Hagerman RJ
(2007). Cognitive, anxiety and mood disorders in the fragile X-associated tremor/ataxia
syndrome. General Hospital Psychiatry, 29(4), 349-356.
69. McConkie-Rosell A, Abrams L, Finucane B, Cronister A, Gane LW, Coffey SM, Sherman S,
Nelson LM, Berry-Kravis E, Hessl D, Chiu S, Street N, Vatave A, & Hagerman RJ (2007).
Recommendations from multi-disciplinary focus groups on cascade testing and genetic
counseling for Fragile X associated disorders. Journal of Genetic Counseling 16(5), 593-
606.
70. Solomon M, Hessl D, Chiu S, Hagerman RJ, & Hendren R (2007). A genetic etiology of PDD
guides treatment. American Journal of Psychiatry 164(4): 575-580.
71. Grigsby J, Brega A, Leehey M, Goodrich G, Jacquemont S, Loesch D, Hagerman PJ, Cogswell
J, Epstein J, Wilson R, Jardini T, Gould E, Bennett R, Hessl D, Cohen S, Cook K, &
Hagerman, RJ (2007). Impairment of executive cognitive functioning in males with fragile
X-associated tremor/ataxia syndrome (FXTAS). Movement Disorders, 22(5), 645-650.
David R. Hessl, PhD, 15
72. Chiu S, Wegelin J, Blank J, Jenkins, Day J, Hessl D, Tassone F, & Hagerman RJ (2007). Early
acceleration of head circumference in children with fragile X syndrome and autism. Journal
of Behavioral and Developmental Pediatrics 28, 31-35.
73. Hessl D, Rivera SR, Koldewyn K, Cordeiro L, Adams J, Tassone F, Hagerman PJ, & Hagerman
RJ (2007). Amygdala dysfunction in men with the fragile X premutation. Brain 130(2),
404-416.
74. Leehey M, Berry-Kravis E, Min S, Hall D, Rice C, Zhang L, Grigsby J, Greco C, Lara R,
Cogswell J, Jacquemont S, Hessl D, Tassone F, Hagerman, RJ, & Hagerman, PJ (2007).
Progression of tremor and ataxia in the fragile X-associated tremor/ataxia syndrome.
Movement Disorders 22(2), 203-206.
75. Bourgeois JA, Farzin F, Brunberg JA, Tassone F, Hagerman PJ, Zhang L, Hessl D, & Hagerman
RJ (006). Dementia with mood symptoms in a fragile X premutation carrier with the fragile
X-associated tremor/ataxia syndrome: Clinical intervention with donepezil and venlafaxine.
The Journal of Neuropsychiatry and Clinical Neurosciences 18:2, 171-177
76. Loesch DZ, Quang M, Dissanayake C, Clifford S, Gould E, Bulhak-Paterson D, Tassone F,
Taylor A, Hessl D, Hagerman RJ, & Huggins R (2006). Molecular and cognitive predictors
of the continuum of autistic behaviors in fragile X. Neuroscience and Biobehavioral
Reviews 31, 315-326.
77. Cohen S, Maysn K, Adams J, Hessl D, Rivera S, Tassone F, Brunberg J, DeCarli C, Zhang L,
Cogswell J, Loesch DZ, Leehey M, Grigsby J, Hagerman PJ, & Hagerman RJ (2006).
Molecular and imaging correlates of the Fragile X-associated Tremor Ataxia Syndrome.
Neurology 67(8),1426-1431.
78. Bourgeois JA, Farzin F, Brunberg JA, Tassone F, Hagerman PJ, Zhang L, Hessl D & Hagerman
RJ (2006). Dementia with mood symptoms in a carrier of the fragile X-associated
tremor/ataxia syndrome (FXTAS): Clinical intervention with donepezil and venlafaxine.
The Journal of Neuropsychiatry and Clinical Neurosciences, 18(2), 171-177.
79. Farzin F, Perry H, Hessl D, Loesch DZ, Cohen J, Bacalman S, Gane LW, Tassone F, Hagerman
PJ, & Hagerman RJ (2006). Autism spectrum disorders and attention deficit/hyperactivity
disorder in boys with the fragile X premutation. Journal of Developmental and Behavioral
Pediatrics, 27(2) S137-S144.
80. Hessl D, Glaser B, Dyer-Friedman J, & Reiss AL (2006). Social behavior and cortisol reactivity
in children with fragile X syndrome. Journal of Child Psychology and Psychiatry, 47(6),
602-610.
81. Greco CM, Berman RF, Martin RM, Tassone F, Schwartz PH, Grigsby J, Hessl D, Becker
EJ, Papazian J, Bacalman S, Leehey MA, Hagerman RJ, & Hagerman PJ (2006).
Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS). Brain,
129, 243-255.
82. Hessl D, Tassone F, Loesch, DZ, Berry-Kravis E, Leehey M, Gane LW, Barbato I, Rice C,
Gould E, Hall DA, Grigsby J, Wegelin JA, Harris S, Lewin F, Weinberg D, Hagerman PJ &
Hagerman RJ (2005). Abnormal elevation of FMR1 mRNA is associated with
psychological symptoms in individuals with the fragile X premutation. American Journal of
Medical Genetics Part B: Neuropsychiatric Genetics 139B: 115-121.
83. Mothersead PK, Conrad K, Hagerman RJ, Greco CM, Hessl D, & Tassone F (2005). Grand
rounds: An atypical progressive dementia in a male carrier of the fragile X premutation: An
example of Fragile X-Associated Tremor/Ataxia Syndrome. Applied Neuropsychology
12(3), 169-78.
David R. Hessl, PhD, 16
84. Hessl D, Deprey L, Ruiz L, Huff HN, & Hagerman RJ (2004). Vagus nerve stimulation in an
adult male with fragile X syndrome. Mental Health Aspects of Developmental Disabilities,
7(3), 107-113.
85. Hagerman RJ, Leavitt BR, Farzin F, Jacquemont S, Greco CM, Brunberg JA, Tassone F,
Hessl D, Harris SW, Zhang L, Jardini T, Gane LW, Ferranti J, Ruiz L, Leehey MA,
Grigsby J, & Hagerman PJ (2004). Fragile X-Associated Tremor/Ataxia Syndrome
(FXTAS) in females with the FMR1 premutation. American Journal of Human
Genetics, 74(5), 1051-1056.
86. Hessl D, Rivera SM & Reiss AL (2004). The neuroanatomy and neuroendocrinology of fragile
X syndrome. Special issue: Fragile X syndrome: Frontiers of understanding gene-brain-
behavior relationships. Mental Retardation and Developmental Disabilities Research
Reviews, 10, 17-24.
87. Dawson G, Ashman SB, Panagiotides H, Hessl D, Self J, Yamada E & Embry L (2003).
Preschool outcomes of children of depressed mothers: Role of maternal behavior,
contextual risk, and children’s brain activity. Child Development, 74(4), 1158-1175.
88. Johnston C, Hessl D, Eliez S, Dyer-Friedman J, Blasey C, Glaser B, & Reiss AL (2003). Factors
associated with parenting stress in mothers of children with fragile X syndrome. Journal of
Behavioral and Developmental Pediatrics, 24(4), 267-275.
89. Glaser B, Hessl D, Dyer-Friedman J, Johnston C, Wisbeck J, Taylor A. & Reiss AL (2003).
Biological and environmental contributions to adaptive behavior in fragile X syndrome.
American Journal of Medical Genetics, 117A, 21-29.
90. Hessl D, Glaser B, Dyer-Friedman J, Blasey C, Gunnar M, Hastie T & Reiss AL (2002). Cortisol
and behavior in fragile X syndrome. Psychoneuroendocrinology, 27, 855-872.
91. Carrion V, Weems C, Ray R, Glaser B, Hessl D, & Reiss AL (2002). Baseline cortisol in
pediatric PTSD. Biological Psychiatry, 51, 575-582.
92. Dyer-Friedman J, Glaser B, Hessl D, Johnston C, Taylor A, Wisbeck J & Reiss AL (2002).
Genetic and environmental influences on the cognitive outcomes of children with fragile X
syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 41(3),
237-244.
93. Tamm L, Menon V, Johnston C, Hessl D, & Reiss AL (2002). fMRI study of cognitive
interference processing in females with fragile X syndrome. Journal of Cognitive
Neuroscience, 14, 160-171.
94. Hessl D, Dyer-Friedman J, Glaser B, Barajas G, Wisbeck J, Taylor A & Reiss AL (2001). The
influence of environmental and genetic factors on behavior problems and autistic symptoms
in boys and girls with fragile X syndrome. Pediatrics, 108(5), p. e88.
95. Johnston C, Eliez S, Dyer-Friedman J, Hessl D, Glaser B, Blasey C, Taylor A, & Reiss AL
(2001). Neurobehavioral phenotype in carriers of the fragile X premutation. American
Journal of Medical Genetics, 103, 314-319.
96. Dawson G, Ashman SB, Hessl D, Spieker S, Frey K, Panagiotides H, & Embry L (2001).
Autonomic and brain electrical activity in securely- and insecurely-attached infants of
depressed mothers. Infant Behavior and Development, 24, 135-149.
97. Dawson G, Frey K, Panagiotides H, Yamada E, Hessl D, & Osterling J (1999). Infants of
depressed mothers exhibit atypical frontal electrical brain activity during interactions with
mother and with a familiar, nondepressed adult. Child Development, 70(5), 1058-1066.
David R. Hessl, PhD, 17
98. Dawson G, Frey K, Self JF, Panagiotides H, Hessl D, Yamada E, & Rinaldi J (1999). Frontal
brain electrical activation in infants of depressed mothers and nondepressed mothers:
Relations to variations in infant behavior. Development and Psychopathology, 11, 589-605.
99. Dawson G, Frey K, Panagiotides H, Osterling J, & Hessl D (1997). Infants of depressed mothers
exhibit atypical frontal brain activity: A replication and extension of previous findings.
Journal of Child Psychology and Psychiatry, 38(2), 179-186.
100. Dawson G, Hessl D, & Frey K (1994). Social influences on early-developing biological and
behavioral systems related to risk for affective disorder. Special Issue: Neural Plasticity,
Sensitive Periods, and Psychopathology. Development and Psychopathology, 6(4), 759-
779.
BOOK CHAPTERS
1. Halkett ES, Wang JY, Hessl D, & Rivera SM (In press). Neuroimaging findings in FXTAS. In F.
Tassone and D. Hall (Eds.). FXTAS, FXPOI and Other Premutation Disorders. Springer.
2. Leigh MJ, Hagerman RJ, & Hessl D (2012). Fragile X syndrome. In RL Hansen and SJ Rogers
(Eds.) Neurodevelopmental Disorders and Their Treatment. Washington, DC: American
Psychiatric Publishing.
3. Schneider A & Hessl D (2011). Fragile X syndrome. In F. Volkmar (Ed.). Encyclopedia of
Autism Spectrum Disorders. Springer: New York, NY.
4. Chiu S, Hessl D, Day J, & Hagerman RJ (2010). Genetic correlates of psychiatric comorbidity:
Fragile X syndrome. In M. Bax and C. Gillberg (Eds.). Co-Morbidities in Developmental
Disorders. Mac Keith Press: London.
5. Schneider A & Hessl D (2011). Fragile X Syndrome: Life-Course and Strategies for
Intervention. In P. Howlin, T. Charman & M. Ghaziuddin (Eds.). SAGE Handbook of
Developmental Disorders. Sage Publications Ltd: London.
6. Hessl D, Green C, Aguilar D, Cordeiro L, McCormick C & Yuhas J (2009). Developmental
Disability and Fragile X Syndrome: Clinical Overview. In: L.R. Squire (Ed.) Encyclopedia
of Neuroscience, volume 3, pp. 487-494. Oxford: Academic Press.
7. Dawson G & Hessl D (1996). Ethical dilemmas in the assessment of maternal depression. In K.
Hoagwood, P. Jensen, & C. Fisher (Eds.), Ethical Issues in Mental Health Research with
Children and Adolescents. Lawrence Erlbaum Associates: New Jersey.
NON PEER REVIEWED PUBLICATIONS
1. Hessl D, Tassone F, Cordeiro L, Koldewyn K, McCormick C, Green C, Yuhas J, Adams J, &
Hagerman RJ (2006). Aggression and self-injurious behavior in boys and young men with
fragile X syndrome. National Fragile X Foundation Quarterly.
2. Hessl D, Dyer-Friedman J, Glaser B, Erba H, & Reiss AL (2002). Genes, schools and family:
What influences cognitive and behavioral outcome in children with fragile X syndrome?
National Fragile X Foundation Quarterly, Spring Edition.
IN PREPARATION/UNDER REVIEW
David R. Hessl, PhD, 18
PRESENTATIONS, ABSTRACTS, AND POSTERS
1. Hessl D (2017). Invited lecture: Behavioral Outcome Measures for IDD Conditions: What
Works and What Doesn't. Presented at: Looking to the Future: The Next 50 Years of
Intellectual and Developmental Disabilities Research at NICHD, Bethesda, April.
2. Hessl D (2017). Keynote: From Understanding Phenotype to Interventions in Fragile X
Syndrome: Some Paths to Better Outcomes. Fragile X Syndrome Workshop, UK Fragile X
Society, St. Catherine’s College, Oxford, England.
3. Hessl D (2016). Behavioral Assessment in Neurodevelopmental Disorder Clinical Trials: We
Can Do Better! And Here’s How (?) MIND Institute Research Seminar Series.
4. Hessl D & Abbeduto L (2016). Innovative approaches to improving language and cognition in
fragile X syndrome. 15th
International Fragile X Conference, San Antonio, TX.
5. Hagerman RJ, Hessl D, Berry-Kravis E, Jacquemont S, Des Portes V, Wolf , Aposto G,
Koumaras B, Stanfield A, and Von Raison F. Can we reverse intellectual and behavioral
problems in adults with fragile X syndrome? Journal of Intellectual Disability Research 59
(9), 791.
6. Hessl D, Sansone S, Berry-Kravis E, Gershon R, Riley K, Schneider A, Crestodina C, Rhodes K,
& Oaklander D (2016). The NIH Toolbox Cognitive Battery for intellectual disabilities:
preliminary feasibility studies and future directions 49th Gatlinburg Conference on
Research and Theory in Intellectual Disabilities. March, San Diego, CA.
7. Berry-Kravis E, Sansone S, Crestodina C, McLennan Y, Chin J, Joshi R, Schneider A, Leigh MJ,
Hagerman R, Hessl D. Sensitivity of the KiTAP executive function battery and an eye
tracking paradigm to effects of AFQ056 in fragile X syndrome. Ann Neurol 2016;80:S413.
8. Sansone S, Berry-Kravis E, Crestodina C, McLennan Y, Hagerman R & Hessl D (2016).
Sensitivity of an eye tracking paradigm as an outcome measure in a fragile X syndrome
targeted treatment clinical trial. 49th Gatlinburg Conference on Research and Theory in
Intellectual Disabilities. March, San Diego, CA.
9. Wadell, P. M., Abucayan, F., Mulgaonkar, A., & Hessl, D. (2014). Social Gaze in Fragile X
Syndrome and Autism. Poster session presented at: AACAP’s 61st annual meeting;
October 20-25; San Diego, CA.
10. Hessl D (2014). Cognitive outcome measures in fragile X syndrome: Limitations, solutions and
future plans. Gordon Research Conference on Fragile X Syndrome and Autism-Related
Conditions. June 1-6, Mount Snow, Vermont.
11. Wang JY, Hessl D, Schneider A, Tassone F, Hagerman RJ, & Rivera SM (2013). Influence of
the FMR1 gene on motor fiber tracts in males with normal and premutation alleles.
Presented at the 1st International Conference on the FMR1 Premutation: Basic Mechanisms
and Clinical Involvement. June 23-26, Perugia, Italy.
12. Schneider A, Muzar Z, Summers S, Tassone F, Seritan A, Rivera SM, Grigsby J, Hessl D, &
Hagerman RJ (2013). Female characteristics of fragile X-associated tremor/ataxia
syndrome. Presented at the 1st International Conference on the FMR1 Premutation: Basic
Mechanisms and Clinical Involvement. June 23-26, Perugia, Italy.
13. Schneider A, Gaines A, Seritan A, Tassone F, Rivera SM, Hagerman RJ, & Hessl D (2013). A
specific psychiatric profile for female carriers of the FMR1 premutation. Presented at the 1st
International Conference on the FMR1 Premutation: Basic Mechanisms and Clinical
Involvement. June 23-26, Perugia, Italy.
David R. Hessl, PhD, 19
14. Basuta K, Lozano R, Schneider A, Hessl D, Hagerman RJ, & Tassone F (2013). Molecular and
behavior variability in a family with FMR1 related disorders, including two compound
heterozygous females. Presented at the 1st International Conference on the FMR1
Premutation: Basic Mechanisms and Clinical Involvement. June 23-26, Perugia, Italy.
15. Schneider A, Johnston C, Tassone F, Sansone S, Abucayan F, Narcisa V, Hagerman PJ,
Hagerman RJ, Rivera SM, & Hessl D (2012). Social cognition and broad autism phenotype
in men with the fragile X premutation. Journal of Intellectual Disability Research 56(1):
925. Presented at the 15th
Society for the Study of Behavioral Phenotypes International
Research Symposium, Leuven, Belgium.
16. Mulgaonkar A, Sansone S, Schneider A, Chavez, A, Abucayan F, Tassone F, Hagerman RJ, &
Hessl D (2012). Cortisol and stress in fragile X premutation carriers. Poster presented at the
13th
International Fragile X Conference, Miami, FL.
17. Johnston C, Schneider A, Tassone F, Sansone S, Rivera S, Hagerman RJ, & Hessl D (2012).
Memory functioning in male premutation carriers without FXTAS. Presented at the 13th
International Fragile X Conference, Miami, FL.
18. Au J, Schneider A, Berkowitz-Sutherland L, Hessl D, Hagerman RJ, & Schweitzer J (2012).
Evaluation of Cogmed working memory training in fragile X. Presented at the 13th
International Fragile X Conference, Miami, FL.
19. Hessl D, Abucayan F, Mulgaonkar A, Schneider A, Sansone S, Chechi T, Leigh MJ, &
Hagerman RJ (2012). Effect of minocycline treatment on attention and social gaze
processing in children with fragile X syndrome. Presented at the 13th
International Fragile X
Conference, Miami, FL.
20. Schneider A, Adams P, Nanakul R, Chechi T, Hagerman R, Olichney JM, & Hessl D (2012).
Differences in cortical hyperexcitability in fragile X syndrome. Presented at the 13th
International Fragile X Conference, Miami, FL.
21. Schneider A, Adams P, Nanakul R, Chechi T, Leigh MJ, Hagerman RJ, Olichney JM, & Hessl D
(2012). Electrocortical changes during a double blind, placebo controlled trial of
minocycline in children with fragile X syndrome. Presented at the 13th
International Fragile
X Conference, Miami, FL.
22. Sansone SM, Widaman KF, Hall SS, Reiss AL, Lightbody A, Kaufmann WE, Berry-Kravis E,
Lachiewicz A, Brown EC, & Hessl D (2012). Psychometric evaluation of the Aberrant
Behavior Checklist factor structure in fragile X syndrome: A multi-site collaborative study.
13th
International Fragile X Conference, Miami, FL.
23. Posussa J, Mulgaonkar A, Schneider A, & Hessl D (2012). Eye tracking as a potential screening
tool for FXTAS in premutation carriers. 13th
International Fragile X Conference, Miami, FL.
24. Hessl D (2012). Proving efficacy in fragile X clinical trials: Measure options, present and future.
Invited presentation at Fragile X and Autism-Related Disorders: From Basic Neuroscience
to Improved Clinical Care. Gordon Research Conference, Stonehill College, Easton, MA.
25. Hessl D (2011). Insights into autism through fragile X research. Invited presentation at the
Autism Working Group of the Stanford Autism Center at Packard Children's Hospital,
Stanford, CA
26. Hessl D, Schneider A, Sumekar T, Cheung K, Hagerman PJ, Roid G (2011). Intelligence
measurement in X linked intellectual disability: Limitations, solutions, and where do we go
from here? 14th
Annual Fragile X and X-Linked Intellectual Disability Conference, Berlin
Germany.
David R. Hessl, PhD, 20
27. Kim S-Y, Burris J, Bassal F, Tassone F, Hessl D, & Rivera SM (2011). Socio-emotional
dysfunction and its relationship with neural correlates of emotional processing in children
and adolescents with fragile X syndrome Society for Neuroscience, Washington DC
28. Russo N, Yesinsky J, Hessl D, & Berry-Kravis E (2011). Feasibility, reproducibility, and
clinical validity of the Pediatric Anxiety Rating Scale (PARS) in fragile X syndrome.
Poster presentation at the Child Neurology Society, Savannah, Georgia
29. Schneider A, Nanakul R, & Hessl D (2010). First Steps into Developing EEG as Medication
Outcome Measure for Targeted Treatments in Fragile X. International Conference on
Genetics and Neurobiology of Mental Retardation, Biennial Conference of the German
Academy of Sciences Leopoldina, National Academy of Sciences, 29th September to 1st
October, 2010, Erlangen, Germany, Molecular Syndromology 2010;1:136-157.
30. Hessl D (2010). Clinical and Physiological Phenotypes in Fragile X-Associated Disorders:
Examples of Outcome Measure Development. John D Wiley Seminar Series . Waisman
Center, University of Wisconsin, Madison, WI
31. Hessl D & Hagerman PJ (2010). FXTAS as a model for understanding neurogenetic disorders.
Translational Grand Rounds, Department of Psychiatry and Behavioral Sciences, UC Davis
32. Rivera SW, Wang J, Koldewyn K, Schneider A, Tassone F, Hagerman RJ, Hagerman PJ,
Iwahashi C, & Hessl D (2010). Gene-brain-behavior relationships in fragile X premutation
carriers: The limbic system. Gatlinburg Conference on Research & Theory in Intellectual &
Developmental Disabilities, Annapolis, MD
33. Hessl D (2010). Cognitive testing in children with intellectual disabilities: A new solution to a
pervasive problem. 25th
Annual Learning and the Brain Conference, San Francisco, CA
34. Wang J, Koldewyn K Hessl D, Selmeczy D, Hagerman RJ, Hagerman PJ, Iwahashi C, Tassone
F, Schneider A, & Rivera S (2009). Fragile X mental retardation-1 gene mRNA as a
predictor for amygdala volume in fragile X premutation men. Poster presented at Society
for Cognitive Neuroscience Annual Meeting, San Francisco, CA
35. Hessl D (2009). What we learn about autism from studying fragile X syndrome. Minds Behind
the MIND lecture series. MIND Institute, UC Davis
36. Hessl D (2008). Outcome measures for clinical trials: What do we have now and what do we
need? FRAXA Investigators Meeting, University of New Hampshire, Durham
37. Hessl D (2008). Thinking outside the box: New neurophysiological and behavioral tools for
clinical research in neurodevelopmental disorders. Presented at the Waisman Center,
University of Wisconsin, Madison
38. Hessl D (2008). Psychophysiology of emotion in fragile X and Down syndromes: Similarities,
contrasts, and implications for treatment. Presented at the Waisman Center, University of
Wisconsin, Madison
39. Farzin F, Rivera SM, Weru J, & Hessl D (2008). Face processing in individuals with fragile X
syndrome: An eye-tracking study. Presented at the 11th International Fragile X Conference,
St Louis, Missouri
40. Adams PE, Adams JS, Nguyen D, Hessl D, Brunburg JA, Tassone F, Zhang L, DeCarli C,
Hagerman PJ, & Hagerman RJ (2008). Psychiatric problems in female fragile X
premutation carriers, with involvement of the hippocampus. Presented at the 11th
International Fragile X Conference, St Louis, Missouri
41. Chavez A, Schneider A, Green C, Nguyen D, Loesch D, Gould E, & Hessl D (2008).
Limitations of the standard IQ score in fragile X syndrome: A proposed solution using an
David R. Hessl, PhD, 21
individual deviation score. Presented at the 11th
International Fragile X Conference, St
Louis, Missouri
42. Hessl D, Schneider A, Cordeiro L, Tassone F, Rivera S, Nguyen D, Gane L, & Hagerman RJ
(2008). Genetic and brain correlates of psychiatric and cognitive functioning in men with
the fragile X premutation. Presented at the 11th
International Fragile X Conference, St
Louis, Missouri
43. Schneider, A, Hessl D, Tassone F, Yuhas, J, Le, L, Chavez, A, Gane, L, & Hagerman RJ (2008)
Two faces of the fragile-X premutation – clinical correlates of CGG repeat size and
methylation Presented at the 11th
International Fragile X Conference, St Louis, Missouri
44. Hessl D (2007) Commonalities in psychophysiological dysfunction in fragile X and autism 10th
International Meeting of the Society for the Study of Behavioural Phenotypes, Sacramento,
CA
45. Rivera, SM, Hessl D, Koldewyn, K, Tassone F, & Hagerman RJ (2007) Brain-based evidence of
limbic system dysfunction in fragile X premutation carriers Presented at the 13th
International Workshop on Fragile X and X-Linked Mental Retardation, Venice, Italy
46. Hessl D, Tassone F, Campbell, A, Cordeiro, L, Yuhas, J, Ornitz, E, & Hagerman RJ (2007)
Prepulse inhibition in fragile X syndrome and FXTAS Presented at the 13th
International
Workshop on Fragile X and X-Linked Mental Retardation, Venice, Italy
47. Hagerman RJ, Soontarapornchai, K, Maselli, R, Fenton-Farell, G, Tassone F, Hessl D, &
Hagerman PJ (2007) Characterization of the neuropathy in the fragile X-associated
tremor/ataxia syndrome (FXTAS) Presented at the 13th
International Workshop on Fragile
X and X-Linked Mental Retardation, Venice, Italy
48. Hessl D, Rivera, S, Koldewyn, K, Cordeiro, L, Adams, J, Tassone F, Hagerman PJ, & Hagerman
RJ (2006) Amygdala dysfunction in men with the fragile X premutation Presented at the
11th
Annual Meeting of the Society for the Study of Behavioural Phenotypes, Royal College
of Surgeons, Dublin, Ireland Journal of Intellectual Disabilities Research, 50, 787
49. Tartaglia, N, Hansen, R, Reynolds, A, Hessl D, Bacalman, S, Goodlin-Jones, B, Deprey, L, &
Hagerman RJ (2006) Attention deficit hyperactivity disorder and autism spectrum disorders
in males with XXY, XYY and XXYY syndromes Presented at the 11th
Annual Meeting of
the Society for the Study of Behavioural Phenotypes, Royal College of Surgeons, Dublin,
Ireland Journal of Intellectual Disabilities Research, 50, 787
50. Hagerman RJ, Adams, J, Adams, P, Nguyen, D, Hessl D, Tassone F, & Hagerman PJ (2006)
FXTAS: A comparison of male vs female involvement Presented at the 11th
Annual
Meeting of the Society for the Study of Behavioural Phenotypes, Royal College of
Surgeons, Dublin, Ireland Journal of Intellectual Disabilities Research, 50, 789
51. Hessl D & Roberts, J (2006) Psychophysiological studies and biophysical outcomes Presented
at the National Institute of Child Health and Human Development Fragile X Meeting,
Atlanta, GA
52. Hessl D, Cordeiro, L, Koldewyn, K, Tassone F, Cohen, S, Green, C, McCormick, C, &
Hagerman RJ (2006) Aggressive behavior in fragile X syndrome: Genetic, physiological,
and environmental factors Presented at the 10th
International Fragile X Conference, Atlanta,
GA
53. Hessl D, Cordeiro, L, Tassone F, & Hagerman RJ (2006) Evidence of reduced
psychophysiological responses to social-emotional stimuli in adult males with the fragile X
premutation Presented at the 10th
International Fragile X Conference, Atlanta, GA
David R. Hessl, PhD, 22
54. Rivera, S, Koldewyn, K, Tassone F, Hagerman RJ, & Hessl D (2006) fMRI evidence of
amygdala dysfunction in men with the fragile X permutation Presented at the 10th
International Fragile X Conference, Atlanta, GA
55. Koldewyn, K, Rivera, S, Hessl D, Tassone F, & Hagerman RJ (2006) Evidence of hippocampal
dysfunction in males with the fragile X premutation Presented at the 10th
International
Fragile X Conference, Atlanta, GA
56. Tartaglia, N, Bacalman, S, Hessl D, Goodlin-Jones, B, Deprey, L, Ono, M, Tsang, S, Davis, S,
Reynolds, A, Wegelin, J, Hansen, R, & Hagerman, R (2006) Autism spectrum disorder in
males with sex chromosome aneuploidy Poster presented at the International Meeting of
Autism Researchers (IMFAR) meeting Montreal, Canada
57. Chiu, S, Wegelin, J, Blank, J, Jenkins, M, Day, J, Hessl D, Tassone F, & Hagerman, R (2006)
Early acceleration of head circumference in children with fragile X syndrome and autism
Poster presented at the International Meeting of Autism Researchers (IMFAR) meeting
Montreal, Canada
58. Hessl D (2006) Psychopathology associated with the fragile X full mutation and premutation
Centers for Disease Control Focused Advisory Group on Psychiatric and Behavioral Issues
in Fragile X Syndrome Sacramento, CA
59. Koldewyn, K, Hessl D, Tassone F, Cordeiro, L, Hagerman RJ & Rivera, S (2006)
Psychophysiological and fMRI evidence of amygdala dysfunction in men with the fragile X
premutation Poster presented at the Annual Cognitive Neuroscience Meeting, San
Francisco, CA
60. Tartaglia, N, Bacalman, S, Goodlin-Jones, B, Deprey, L, Hessl D, Ono, M, Tsang, S, Davis, S,
Reynolds, A, Hansen, R, Hagerman, R (2006) Autism spectrum disorders in males with sex
chromosome aneuploidy Poster presented at the International Meeting for Autism Research,
Montreal, Canada
61. Hessl D (2006) Autism: Best practices in clinical assessment Presented at the 5th
Annual
Developmental Disabilities Conference, University of California, San Francisco, CA
62. Hessl D (2006) Identification and treatment of anxiety and depression in trisomy X and XYY
syndromes Presented at the First National Conference on Trisomy X and XYY
Sacramento, CA
63. Koldewyn, K, Rivera, S, Hessl D, Tassone F, & Hagerman RJ (2005) Evidence of hippocampal
dysfunction in males with the fragile X premutation Poster presented at the 35th
Annual
Society for Neuroscience Meeting, Washington, DC
64. Hessl D, Tassone F, Loesch, DZ, Berry-Kravis E, Leehey, M, Gane LW, Barbato, I, Rice, C,
Gould, E, Hall, DA, Grigsby, J, Wegelin, JA, Harris, S, Lewin, F, Weinberg D, Hagerman
PJ, & Hagerman RJ (2005) Abnormal elevation of FMR1 mRNA is associated with
psychological symptoms in individuals with the fragile X premutation Presented at the 12th
International Workshop on Fragile X and X-Linked Mental Retardation, Williamsburg, VA
65. Hessl D (2005) Hyperarousal, stress, and aggression in fragile X syndrome Presented at
National Fragile X Awareness Day, Sacramento, CA
66. Zhang, L, Coffey, S, Aguis, M, Adams, J, Nowicki, S, Tartaglia, N, Ono, M, Cook, K, Yuhas, J,
Barbato, I, Harris, S, Apperson, M, Gane, L, Tassone F, Hessl D, Cordeiro, L, Brunberg, J,
Hall, D, Leehey, M, Hagerman, P, Hagerman, R (2005) Clinical and MR abnormalities in
females carrying the FMR1 premutation Neurology, 64(6), A92-A93 Presented at the 57th
Annual Meeting of the American Academy of Neurology, Miami Beach, Florida
David R. Hessl, PhD, 23
67. Hessl D (2005) Stress and anxiety in autism and fragile X syndrome Presented at the 1st
International Conference and Clinic on Autism and Fragile X Syndrome, Dubai, United
Arab Emirates
68. Hessl D, Pinter, J, Deprey, L, Chiu, S, Winn, C & Hagerman, R (2005) Autism in a young man
with 8p23 deletion syndrome: Expanding the phenotype? Presented at the 66th
Canadian
Psychological Association Annual Convention, Montreal, Canada
69. Chiu, S, Hessl D, Day, J, Copeland, L, Maddock, R, Hagerman, R & Hendren R (2004)
Pediatric psychosis in fragile X syndrome Presented at the 51st Annual Meeting of the
American Academy of Child and Adolescent Psychiatry, Washington DC
70. Hessl D, Cohen, S, Perry, H, Tassone F, & Hagerman RJ (2004) Potentiated startle and galvanic
skin responses to social and emotional stimuli in children with fragile X: A pilot study
Presented at the Ninth International Fragile X Conference, Washington, DC
71. Hessl D, Tassone F, Perry, H, Cohen, S, Yehuda, R, Makotkine, I, Hagerman PJ, & Hagerman
RJ (2004) Glucocorticoid receptor (GR) mRNA and lymphocyte GR concentration in males
with fragile X syndrome Presented at the Ninth International Fragile X Conference,
Washington, DC
72. Cordeiro, L, Hessl D, Tassone F, Gould, E, Loesch, D, Barbato, I, Perry, H, Gane LW,
Hagerman PJ, & Hagerman RJ (2004) Genotype-phenotype relationships in children with
fragile X: Association between FMR1 protein expression and behavior Presented at the
Ninth International Fragile X Conference, Washington, DC
73. Hessl D, Cohen, S, Gane, L, Jardini, T, Tassone F, Hagerman, P, & Hagerman RJ Structural
neuroimaging and molecular correlates of psychopathology in adult males with the FMR1
premutation (2003) American Journal of Medical Genetics, 73(5), 266 Proceedings of the
53rd
Annual Meeting of the American Society of Human Genetics, Los Angeles
74. Cohen, S, Jaquemont, S, Hessl D, Jardini, T, Harris, S, Tong-Turnbeaugh, R, Jagust, W, Rivera,
S, Gane, L, Tassone F, Hagerman, P, & Hagerman, R (2003) Neuroimaging correlates of
fragile X-associated tremor/ataxia syndrome (FXTAS) Presented at the 11th
International
Workshop on Fragile X Syndrome and X-Linked Mental Retardation, Paphos, Cyprus
75. Hagerman, R, Zhang, L, Brunberg, J, Hessl D, Jacquemont, S, Tassone F, Harris, S, Jardini, T, &
Hagerman PJ (2003) Two female cases of the fragile X premutation tremor/ataxia
syndrome: Cognitive, molecular, and radiological studies Presented at the 11th
International
Workshop on Fragile X Syndrome and X-Linked Mental Retardation, Paphos, Cyprus
76. Hessl D (2003) Psychophysiology of Emotion in Neurodevelopmental Disorders Presented at
Neurodevelopmental Disorders: From Research to Practice, Sacramento, CA
77. Hessl D (2003) Genetic, Environmental, and Physiological Contributions to Behavior in Fragile
X Syndrome Presented at La Trobe University, Bandoora, Australia
78. Hagerman, R, Hessl D, Hess, L, Lemons, K, & Stackhouse, T (2002) Panel on hyperarousal
Presented at Neurodevelopmental Disorders: From Research to Practice, Sacramento, CA
79. Hessl D (2002) Is it all genes? The impact of environmental and neurohormonal variables on
outcome in children with fragile X Presented at the Eighth International Fragile X
Conference, Chicago, IL
80. Dyer-Friedman, J., Hessl D, Glaser, B., Kosaraju, A., & Reiss, A. (2001). The Special
Curriculum Opportunity Rating Scale (SCORS): A measure of educational and therapeutic
effectiveness. Presented at the 14th
Annual Research Conference, A System of Care for
Children’s Mental Health: Expanding the Research Base, Tampa, FL.
David R. Hessl, PhD, 24
81. Hessl D, Reiss, A., & Merin, N. (2000). Magnetic resonance imaging during processing of gaze
in fragile X syndrome. Presented at the Seventh International Fragile X Conference, Los
Angeles, CA, July 2000.
82. Hessl D (2000). Assessment of stress hormone (cortisol) levels in children with fragile X
syndrome. Presented at the Seventh International Fragile X Conference, Los Angeles, CA.
83. Reiss, A., Dyer-Friedman, J., Hessl D, & Glaser, B. (2000). Factors predicting outcome in
fragile X syndrome. Presented at the Seventh International Fragile X Conference, Los
Angeles, CA.
84. Taylor, A., Patterson, K., Dyer, P., Linden, M., Murphy, J., Tassone F, Blasey, C., Hessl D,
Reiss, A., Butler, E., Loesch, D. & Hagerman R. (2000). FMRP expression and clinical
correlates in mosaic males, males with a partially methylated full mutation, and females
with a full mutation. Presented at the Seventh International Fragile X Conference, Los
Angeles, CA.
85. Hessl D & Davidson, J. (1999). A prospective study of stress and health in young children: Is
immune reactivity a source of resilience? Poster presented at the Society for Research in
Child Development Meeting, Albuquerque, NM.
86. Dawson, G., Frey, K., Panagiotides, H., Self, J., Hessl D, & Yamada, E. (1997). Atypical frontal
brain activity in infants of depressed mothers: The role of maternal behavior. Presented at
the Meeting of the Society for Research in Child Development as part of a symposium on
“The Impact of Trauma and Adversity on Behavioral and Physiological Development:
Clarifying the Issues.”
87. Hessl D, Dawson, G., Frey, K., Panagiotides, H., Self, J., Yamada, E., & Osterling, J. (1998) A
longitudinal study of children of depressed mothers: Psychobiological findings related to
stress. In D.M. Hann, L.C. Huffman, K.K. Lederhendler, and D. Meinecke (Eds.)
Advancing research on developmental plasticity: Integrating the behavioral science and the
neuroscience of mental health. National Institute of Mental Health: Bethesda, MD.
88. Dawson, G., Frey, K., Hessl D, Panagiotides, H., & Self, J (1995). Infants of depressed mothers
exhibit atypical frontal brain activity: A replication of previous findings. Presented at the
Meeting of the Society for Research in Child Development, Indianapolis, IN.
89. Hessl D (1998). Fathering young children: Maternal depression, paternal mental health, and
marital adjustment as determinants of involvement and parenting. Dissertation Abstracts
International: Section B: The Sciences & Engineering, 58(8-B), 4450.