CURRICULUM VITAE

PERSONAL

Name Date of birth Marital Status Nationality Address (Professional) Contact Numbers e-mail address

Dimitrios Petrou Bogdanos 18th September 1968 Married (one child) Greek Department of Rheumatology, Faculty of Medicine School of Health Sciences, University of Thessaly University General Hospital of Larissa 4110 Biopolis, Larissa, Greece +30 2410 555138; +30 6938 606 510 +44 7493038323 bogdanos@med.uth.gr;

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ACADEMIC QUALIFICATIONS July 1997

May 2005

MD, Aristotle University of Thessalonika, Thessalonika, Greece

PhD in Liver Immunology/Hepatology, University College

London, University of London, UK

CURRENT POST/ PAST & PRESENT APPOINTMENTS 04/1998 – 03/2001 (06/2001 –09/2001) 10/2001 – 12/2002 01/2003–05/2005 01/2006 – 05/2007 May 2007 – September 2011 September 2011- October 2013

Clinical Research Fellow, Institute of Hepatology, Royal Free and University College London Medical School & Hospitals (Director: Professor Roger Williams; Head: Professor Diego Vergani) Sir Yule Bogue Visiting Research Scientist, Diabetes Group, Department of Endocrinology, Internal Medicine, Yale School of Medicine (Head: Professor Li Wen) Clinical Research Fellow, Institute of Hepatology, Royal Free and University College London Medical School & Hospitals(Director: Professor Roger Williams; Head: Professor Diego Vergani) Clinical Research Fellow and PhD Student, Alex Mowat Laboratory, Institute of Liver Studies, King’s College London School of Medicine at King’s College Hospital (Academic Director: Professor Giorgina Mieli-Vergani; Clinical Director Professor Nigel Heaton; Head: Professor Diego Vergani) Affiliated Principal Investigator, General Secreteriat for Research and Technology, Hellenic Ministry of Development (ENTER EU 2004 Programme), and of the Department of Internal Medicine and Research Laboratory, Division of Medicine, General University Hospital of Larissa, Greece (Director & Head: Professor George N. Dalekos) Clinical Senior Lecturer in Liver Immunopathology/(Hon) Consultant Physician, Institute of Liver Studies, King’s College London School of Medicine at King’s College Hospital (Academic Director: Professor Giorgina Mieli-Vergani; Clinical Director Professor Nigel Heaton; Head: Professor Diego Vergani) Responsible for the Specialised Primary Biliary Cirrhosis-Liver Outpatient Clinic) Participating on a regular basis in the Abnormal Liver Function Tests Clinic-Liver Outpatient Clinic (Από το 2010 –Σεπ 2011)

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Current Posts

Division of Medicine, School of Health Sciences, University of Thessaly, General University Hospital of Larissa, Greece (Director: Professor Christos Papandreou) Assistant Professor (Tenure post), Department of Rheumatology, Division of Medicine, School of Health Sciences, University of Thessaly, General University Hospital of Larissa, Greece (Director: Professor Lazaros Sakkas) Head, Cellular Immunotherapy & Molecular Immunodiagnostics Group, Biomedical Section, Institute of Research & Technology, Thessaly, Greece (Director: Professor Elias Houstis)

Current Clinical Duties

Responsible for the In-Patient Clinic & for the clinical management of the

patients on a daily basis

Responsible for the clinical management of patients treated in the 1-day

Therapy Unit of the Rheumatology Clinic

Ward Rounds on a daily basis

Specialists On-call duties on 1/6 rota (4-6 on calls per month)

Out-Patients Clinic activities on a regular basis

Participation in Clinical Trials run by the Department

Chair/Co-chair/Member of Multidisciplinary meetings

Consultations on In-Patient cases of other Departments/Clinics

Current Academic Activities

Undergratuate teaching of 3rd, 4th and 6th year Medical Students

Postgraduate teaching (teaching in MSc Courses of the Faculty of Medicine,

Schoool of Helath Sciences

PhD student supervision (currently of 4 PhD students (1st supervisor in 2).

Successful completion of all 5 PhD studentships (2 at KCL, 3 at UTH)

Clinical Governance

Mandatory Training

Grant Application drafting for research funding

Continuing Professional Development

Academic Tutor 2013-2014 & 2014-2015

Active Research (detailed below as publications, funding and collaborations)

Member of the General Assembly of the Faculty of Medicine 2013-2014

Member of the Specialiazed Synthesis’ Assembly of the Faculty of Medicine

2013-2014

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LIST OF PUBLICATIONS

Total: 181

Deposited in Pubmed: 157

Additional (non-deposited in Pubmed): 24

Papers Deposited in Pubmed http://www.ncbi.nlm.nih.gov/pubmed/?term=Bogdanos

1: Sakkas LI, Bogdanos DP. Systemic sclerosis: new evidence re-enforces the role of B cells. Autoimmun Rev. 2015 Oct 20. pii: S1568-9972(15)00217-7. doi: 10.1016/j.autrev.2015.10.005. [Epub ahead of print] PubMed PMID: 26497107. Review article 2: Mavropoulos A, Simopoulou T, Varna A, Liaskos C, Katsiari C, Bogdanos DP, Sakkas LI. B regulatory cells are decreased and functionally impaired in patients with systemic sclerosis. Arthritis Rheumatol. 2015 Sep 28. doi: 10.1002/art.39437. [Epub ahead of print] PubMed PMID: 26414243. Original article 3: Pavlidis P, Komorowski L, Teegen B, Liaskos C, Koutsoumpas AL, Smyk DS, Perricone C, Mytilinaiou MG, Stocker W, Forbes A, Bogdanos DP. Diagnostic and clinical significance of Crohn's disease-specific pancreatic anti-GP2 and anti-CUZD1 antibodies. Clin Chem Lab Med. 2015 Jul 18. doi: 10.1515/cclm-2015-0376. [Epub ahead of print] PubMed PMID: 26351932. Original article

4: Villalta D, Mytilinaiou MG, Elsner M, Hentschel C, Cuccato J, Somma V, Schierack P, Roggenbuck D, Bogdanos DP. Autoantibodies to asialoglycoprotein receptor (ASGPR) in patients with autoimmune liver diseases. Clin Chim Acta. 2015 Oct 23;450:1-5. doi: 10.1016/j.cca.2015.07.021. Epub 2015 Jul 26. PubMed PMID: 26220739. Original article 5: Norman GL, Gatselis NK, Shums Z, Liaskos C, Bogdanos DP, Koukoulis GK, Dalekos GN. Cartilage oligomeric matrix protein: A novel non-invasive marker for assessing cirrhosis and risk of hepatocellular carcinoma. World J Hepatol. 2015 Jul 18;7(14):1875-83. doi: 10.4254/wjh.v7.i14.1875. Original 6: Efe C, Bogdanos DP. Reply: To PMID 25002309. Dig Dis Sci. 2015 Apr;60(4):1107-8. PubMed PMID: 26086058. Letter 7: Scholz J, Grossmann K, Knütter I, Hiemann R, Sowa M, Röber N, Rödiger S,

Schierack P, Reinhold D, Bogdanos DP, Meroni PL, Radice A, Conrad K, Roggenbuck D. Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing. Clin Chem Lab Med. 2015 May 15. pii: /j/cclm.ahead-of-print/cclm-2015-0083/cclm-2015-0083.xml. doi: 10.1515/cclm-2015-0083. [Epub ahead of print] PubMed PMID: 26020561. Original 8: Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D. Correction: Simultaneous Automated Screening and Confirmatory Testing for Vasculitis-Specific ANCA. PLoS One. 2015 May 13;10(5):e0127933. doi: 10.1371/journal.pone.0127933. eCollection 2015. PubMed PMID: 25970179; PubMed

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Central PMCID: PMC4430479. Not listed in the total number of papers 9: Bogdanos DP, Smyk DS, Rigopoulou EI, Sakkas LI, Shoenfeld Y. Infectomics and autoinfectomics: a tool to study infectious-induced autoimmunity. Lupus. 2015 Apr;24(4-5):364-73. doi: 10.1177/0961203314559088. PubMed PMID: 25801879. 10: Gkretsi V, Bogdanos DP. Experimental evidence of Migfilin as a new therapeutic target of hepatocellular carcinoma metastasis. Exp Cell Res. 2015 Jun 10;334(2):219-27. doi: 10.1016/j.yexcr.2015.03.002. Epub 2015 Mar 12. PubMed PMID: 25773778. 11: Gkretsi V, Bogdanos DP. Elimination of Ras Suppressor-1 from hepatocellular carcinoma cells hinders their in vitro metastatic properties. Anticancer Res. 2015 Mar;35(3):1509-12. PubMed PMID: 25750304. 12: Sakkas LI, Simopoulou T, Katsiari C, Bogdanos DP, Chikanza IC. Early systemic

sclerosis-opportunities for treatment. Clin Rheumatol. 2015 Aug;34(8):1327-31. doi: 10.1007/s10067-015-2902-5. Epub 2015 Feb 26. PubMed PMID: 25711876. 13: Roggenbuck D, Röber N, Bogdanos DP, Goihl A, Reinhold D, Conrad K, Laass MW. Autoreactivity to isoforms of glycoprotein 2 in inflammatory bowel disease. Clin Chim Acta. 2015 Mar 10;442:82-3. doi: 10.1016/j.cca.2015.01.018. Epub 2015 Jan 24. PubMed PMID: 25625482. 14: Koutsoumpas AL, Smyk DS, Bogdanos DP. E. coli Induced Experimental Model of Primary Biliary Cirrhosis: At Last. Int J Hepatol. 2014;2014:848373. doi: 10.1155/2014/848373. Epub 2014 Dec 16. Review. PubMed PMID: 25580301; PubMed Central PMCID: PMC4280654. 15: Liaskos C, Spyrou V, Athanasiou LV, Orfanidou T, Mavropoulos A, Rigopoulou EI, Amiridis GS, Shoenfeld Y, Billinis C, Bogdanos DP. Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis.

Clin Res Hepatol Gastroenterol. 2015 Jun;39(3):384-90. doi: 10.1016/j.clinre.2014.12.001. Epub 2015 Jan 6. PubMed PMID: 25575461. 16: Cantarini L, Rigante D, Vitale A, Napodano S, Sakkas LI, Bogdanos DP, Shoenfeld Y. Intravenous immunoglobulins (IVIG) in systemic sclerosis: a challenging yet promising future. Immunol Res. 2015 Mar;61(3):326-37. doi: 10.1007/s12026-014-8615-z. PubMed PMID: 25550086. 17: Pavlidis P, Shums Z, Koutsoumpas AL, Milo J, Papp M, Umemura T, Lakatos PL, Smyk DS, Bogdanos DP, Forbes A, Norman GL. Diagnostic and clinical significance of Crohn's disease-specific anti-MZGP2 pancreatic antibodies by a novel ELISA. Clin Chim Acta. 2015 Feb 20;441:176-81. doi: 10.1016/j.cca.2014.12.010. Epub 2014 Dec 12. PubMed PMID: 25512163. 18: Roggenbuck D, Vermeire S, Hoffman I, Reinhold D, Schierack P, Goihl A, von Arnim U, De Hertogh G, Polymeros D, Bogdanos DP, Bossuyt X. Evidence of Crohn's

disease-related anti-glycoprotein 2 antibodies in patients with celiac disease. Clin Chem Lab Med. 2015 Aug 1;53(9):1349-57. doi: 10.1515/cclm-2014-0238. PubMed PMID: 25411995. 19: Raszeja-Wyszomirska J, Wunsch E, Krawczyk M, Rigopoulou EI, Bogdanos DP, Milkiewicz P. Prospective evaluation of PBC-specific health-related quality of life questionnaires in patients with primary sclerosing cholangitis. Liver Int. 2015 Jun;35(6):1764-71. doi: 10.1111/liv.12730. Epub 2014 Dec 4. PubMed PMID: 25388280. 20: Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E,

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Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D. Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA. PLoS One. 2014 Sep 16;9(9):e107743. doi: 10.1371/journal.pone.0107743. eCollection 2014 21: Sakkas LI, Bogdanos DP, Katsiari C, Platsoucas CD. Anti-citrullinated peptides as autoantigens in rheumatoid arthritis-relevance to treatment. Autoimmun Rev. 2014 Nov;13(11):1114-20. doi: 10.1016/j.autrev.2014.08.012. Epub 2014 Aug 23. Review. PubMed PMID: 25182207. 22: Polymeros D, Tsiamoulos ZP, Koutsoumpas AL, Smyk DS, Mytilinaiou MG, Triantafyllou K, Bogdanos DP, Ladas SD. Bioinformatic and immunological analysis reveals lack of support for measles virus related mimicry in Crohn's disease. BMC Med. 2014 Aug 28;12:139. doi: 10.1186/s12916-014-0139-9. PubMed PMID: 25168804; PubMed Central PMCID: PMC4171545.

23: Zachou K, Gampeta S, Gatselis NK, Oikonomou K, Goulis J, Manoussakis MN, Renaudineau Y, Bogdanos DP, Dalekos GN. Anti-SLA/LP alone or in combination with anti-Ro52 and fine specificity of anti-Ro52 antibodies in patients with autoimmune hepatitis. Liver Int. 2015 Feb;35(2):660-72. doi: 10.1111/liv.12658. Epub 2014 Aug 27. PubMed PMID: 25113420. 24: Efe C, Kav T, Aydin C, Cengiz M, Imga NN, Purnak T, Smyk DS, Torgutalp M, Turhan T, Ozenirler S, Ozaslan E, Bogdanos DP. Low serum vitamin D levels are associated with severe histological features and poor response to therapy in patients with autoimmune hepatitis. Dig Dis Sci. 2014 Dec;59(12):3035-42. doi: 10.1007/s10620-014-3267-3. Epub 2014 Jul 8. PubMed PMID: 25002309. 25: Maslyanskiy A, Lazareva N, Olinek P, Schierack P, Hentschel C, Cuccato J, Bogdanos DP, Lapin SV, Roggenbuck D. Anti-hnRNP B1 (RA33) autoantibodies are associated with the clinical phenotype in Russian patients with rheumatoid arthritis and systemic sclerosis. J Immunol Res. 2014;2014:516593. doi:

10.1155/2014/516593. Epub 2014 May 4. PubMed PMID: 24883333; PubMed Central PMCID: PMC4027001. 26: Milkiewicz M, Kopycińska J, Kempińska-Podhorodecka A, Haas T, Bogdanos DP, Elias E, Milkiewicz P. Ursodeoxycholic acid influences the expression of p27kip1 but not FoxO1 in patients with non-cirrhotic primary biliary cirrhosis. J Immunol Res. 2014;2014:921285. doi: 10.1155/2014/921285. Epub 2014 Feb 5. PubMed PMID: 24741631; PubMed Central PMCID: PMC3987973. 27: Kotarska K, Wunsch E, Kempińska-Podhorodecka A, Raszeja-Wyszomirska J, Bogdanos DP, Wójcicki M, Milkiewicz P. Factors affecting health-related quality of life and physical activity after liver transplantation for autoimmune and nonautoimmune liver diseases: a prospective, single centre study. J Immunol Res. 2014;2014:738297. doi: 10.1155/2014/738297. Epub 2014 Mar 4. PubMed PMID: 24741621; PubMed Central PMCID: PMC3987938.

28: Mavropoulos A, Bogdanos DP, Liaskos C, Orfanidou T, Simopoulou T, Zafiriou E, Sakkas LI, Rigopoulou EI. Flow cytometric detection of p38 MAPK phosphorylation and intracellular cytokine expression in peripheral blood subpopulations from patients with autoimmune rheumatic diseases. J Immunol Res. 2014;2014:671431. doi: 10.1155/2014/671431. Epub 2014 Feb 3. PubMed PMID: 24741615; PubMed Central PMCID: PMC3987974. 29: Smyk DS, Koutsoumpas AL, Mytilinaiou MG, Rigopoulou EI, Sakkas LI, Bogdanos DP. Helicobacter pylori and autoimmune disease: cause or bystander. World J Gastroenterol. 2014 Jan 21;20(3):613-29. doi: 10.3748/wjg.v20.i3.613. Review. PubMed PMID: 24574735; PubMed Central PMCID: PMC3921471.

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30: Rigopoulou EI, Bogdanos DP. Is primary biliary cirrhosis rare or common? The truth lies somewhere in between. Liver Int. 2014 Aug;34(7):e165-7. doi: 10.1111/liv.12488. PubMed PMID: 24517310. 31: Bogdanos DP, Smyk D, Shoenfeld Y. The microbiome of the lung. Isr Med Assoc J. 2013 Dec;15(12):766-7. PubMed PMID: 24449982. 32: Roggenbuck D, Reinhold D, Schierack P, Bogdanos DP, Conrad K, Laass MW. Crohn's disease specific pancreatic antibodies: clinical and pathophysiological challenges. Clin Chem Lab Med. 2014 Apr;52(4):483-94. doi: 10.1515/cclm-2013-0801. Review. PubMed PMID: 24231127. 33: Smyk DS, Mytilinaiou MG, Grammatikopoulos T, Knisely AS, Mieli-Vergani G, Bogdanos DP, Vergani D. Primary biliary cirrhosis-specific antimitochondrial antibodies in neonatal haemochromatosis. Clin Dev Immunol. 2013;2013:642643. doi:

10.1155/2013/642643. Epub 2013 Sep 19. PubMed PMID: 24171034; PubMed Central PMCID: PMC3792542. 34: Mavropoulos A, Rigopoulou EI, Liaskos C, Bogdanos DP, Sakkas LI. The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis. Clin Dev Immunol. 2013;2013:569751. doi: 10.1155/2013/569751. Epub 2013 Sep 12. Review. PubMed PMID: 24151518; PubMed Central PMCID: PMC3787653. 35: Iacovakis C, Mamuris Z, Moutou KA, Touloudi A, Hammer AS, Valiakos G, Giannoulis T, Stamatis C, Spyrou V, Athanasiou LV, Kantere M, Asferg T, Giannakopoulos A, Salomonsen CM, Bogdanos DP, Birtsas P, Petrovska L, Hannant D, Billinis C. Polarisation of major histocompatibility complex II host genotype with pathogenesis of European Brown Hare syndrome virus. PLoS One. 2013 Sep 19;8(9):e74360. doi: 10.1371/journal.pone.0074360. eCollection 2013. PubMed PMID: 24069299; PubMed Central PMCID: PMC3778001.

36: Mavropoulos A, Orfanidou T, Liaskos C, Smyk DS, Spyrou V, Sakkas LI, Rigopoulou EI, Bogdanos DP. p38 MAPK Signaling in Pemphigus: Implications for Skin Autoimmunity. Autoimmune Dis. 2013;2013:728529. doi: 10.1155/2013/728529. Epub 2013 Jul 10. PubMed PMID: 23936634; PubMed Central PMCID: PMC3722958. 37: Liberal R, Grant CR, Sakkas L, Bizzaro N, Bogdanos DP. Diagnostic and clinical significance of anti-centromere antibodies in primary biliary cirrhosis. Clin Res Hepatol Gastroenterol. 2013 Dec;37(6):572-85. doi: 10.1016/j.clinre.2013.04.005. Epub 2013 Jul 19. PubMed PMID: 23876351. 38: Smyk DS, Orfanidou T, Invernizzi P, Bogdanos DP, Lenzi M. Vitamin D in autoimmune liver disease. Clin Res Hepatol Gastroenterol. 2013 Nov;37(5):535-45. doi: 10.1016/j.clinre.2013.05.016. Epub 2013 Jul 8. Review. PubMed PMID: 23845396. 39: Pavlidis P, Forbes A, Bogdanos DP. Anti-GP2 antibodies in inflammatory bowel

disease patients with ileal pouch. J Crohns Colitis. 2013 Dec;7(11):e602-3. doi: 10.1016/j.crohns.2013.06.010. Epub 2013 Jul 9. PubMed PMID: 23845232. 40: Mahler M, Bogdanos DP, Pavlidis P, Fritzler MJ, Csernok E, Damoiseaux J, Bentow C, Shums Z, Forbes A, Norman GL. PR3-ANCA: a promising biomarker for ulcerative colitis with extensive disease. Clin Chim Acta. 2013 Sep 23;424:267-73. doi: 10.1016/j.cca.2013.06.005. Epub 2013 Jun 24. PubMed PMID: 23806819. 41: Somma V, Ababneh H, Ababneh A, Gatti S, Romagnoli V, Bendia E, Conrad K, Bogdanos DP, Roggenbuck D, Ciarrocchi G. The Novel Crohn's Disease Marker

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Anti-GP2 Antibody Is Associated with Ileocolonic Location of Disease. Gastroenterol Res Pract. 2013;2013:683824. doi: 10.1155/2013/683824. Epub 2013 May 15. PubMed PMID: 23762038; PubMed Central PMCID: PMC3671301. 42: Roggenbuck D, Reinhold D, Werner L, Schierack P, Bogdanos DP, Conrad K. Glycoprotein 2 antibodies in Crohn's disease. Adv Clin Chem. 2013;60:187-208. Review. PubMed PMID: 23724745. 43: Bogdanos DP, Gao B, Gershwin ME. Liver immunology. Compr Physiol. 2013 Apr;3(2):567-98. doi: 10.1002/cphy.c120011. Review. PubMed PMID: 23720323; PubMed Central PMCID: PMC4201126. 44: Liaskos C, Rigopoulou EI, Orfanidou T, Bogdanos DP, Papandreou CN. CUZD1 and anti-CUZD1 antibodies as markers of cancer and inflammatory bowel diseases. Clin Dev Immunol. 2013;2013:968041. doi: 10.1155/2013/968041. Epub 2013 Apr 22. Review. PubMed PMID: 23710207; PubMed Central PMCID: PMC3654630.

45: Raszeja-Wyszomirska J, Wunsch E, Kempinska-Podhorodecka A, Smyk DS, Bogdanos DP, Milkiewicz M, Milkiewicz P. TRAF1-C5 affects quality of life in patients with primary biliary cirrhosis. Clin Dev Immunol. 2013;2013:510547. doi: 10.1155/2013/510547. Epub 2013 Apr 28. PubMed PMID: 23710202; PubMed Central PMCID: PMC3655458. 46: Liaskos C, Spyrou V, Roggenbuck D, Athanasiou LV, Orfanidou T, Mavropoulos A, Reinhold D, Rigopoulou EI, Amiridis GS, Billinis C, Bogdanos DP. Crohn's disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: implications for the pathogenesis of the human disease. Autoimmunity. 2013 Sep;46(6):388-94. doi: 10.3109/08916934.2013.786047. Epub 2013 May 2. PubMed PMID: 23638886. 47: Kundzer AV, Volkova MV, Bogdanos DP, Rödiger S, Schierack P, Generalov I, Nevinsky GA, Roggenbuck D. Deoxyribonuclease activity of polyclonal IgGs: a

putative serological marker in patients with spondyloarthritides. Immunol Res. 2013 Jul;56(2-3):457-64. doi: 10.1007/s12026-013-8424-9. PubMed PMID: 23592052. 48: Bogdanos DP, Smyk DS, Invernizzi P, Rigopoulou EI, Blank M, Sakkas L, Pouria S, Shoenfeld Y. Tracing environmental markers of autoimmunity: introducing the infectome. Immunol Res. 2013 Jul;56(2-3):220-40. doi: 10.1007/s12026-013-8399-6. Review. PubMed PMID: 23592050. 49: Invernizzi P, Bossuyt X, Bogdanos DP. Serum autoantibodies: from identification to clinical relevance. Clin Dev Immunol. 2013;2013:382069. doi: 10.1155/2013/382069. Epub 2013 Mar 20. PubMed PMID: 23573110; PubMed Central PMCID: PMC3615582. 50: Smyk D, Rigopoulou EI, Bizzaro N, Bogdanos DP. Hair dyes as a risk for autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis. Auto Immun Highlights. 2012 Jan 13;4(1):1-9. doi: 10.1007/s13317-011-0027-7.

eCollection 2013 Apr. PubMed PMID: 26000137; PubMed Central PMCID: PMC4389085. 51: Roggenbuck D, Hiemann R, Bogdanos DP, Reinhold D, Conrad K. Standardization of automated interpretation of immunofluorescence tests. Clin Chim Acta. 2013 Jun 5;421:168-9. doi: 10.1016/j.cca.2013.03.019. Epub 2013 Mar 26. PubMed PMID: 23537734. 52: Radzimski C, Probst C, Teegen B, Rentzsch K, Blöcker IM, Dähnrich C, Schlumberger W, Stöcker W, Bogdanos DP, Komorowski L. Development of a recombinant cell-based indirect immunofluorescence assay for the determination of autoantibodies against soluble liver antigen in autoimmune hepatitis. Clin Dev

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Immunol. 2013;2013:572815. doi: 10.1155/2013/572815. Epub 2013 Jan 16. PubMed PMID: 23401700; PubMed Central PMCID: PMC3562650. 53: Roggenbuck D, Bogdanos DP, Conrad K. Loss of tolerance to one or two major targets in Crohn's disease or just cross-reactivity? J Crohns Colitis. 2013 Aug;7(7):e273-4. doi: 10.1016/j.crohns.2012.12.013. Epub 2013 Jan 20. PubMed PMID: 23337370. 54: Probst C, Radzimski C, Blöcker IM, Teegen B, Bogdanos DP, Stöcker W, Komorowski L. Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against "rings and rods"-associated inosine-5'-monophosphate dehydrogenase 2 in viral hepatitis C. Clin Chim Acta. 2013 Mar 15;418:91-6. doi: 10.1016/j.cca.2013.01.003. Epub 2013 Jan 16. PubMed PMID: 23333419. 55: Willitzki A, Hiemann R, Peters V, Sack U, Schierack P, Rödiger S, Anderer U,

Conrad K, Bogdanos DP, Reinhold D, Roggenbuck D. New platform technology for comprehensive serological diagnostics of autoimmune diseases. Clin Dev Immunol. 2012;2012:284740. doi: 10.1155/2012/284740. Epub 2012 Dec 19. Review. PubMed PMID: 23316252; PubMed Central PMCID: PMC3536031. 56: Bogdanos DP, Smyk DS, Invernizzi P, Rigopoulou EI, Blank M, Pouria S, Shoenfeld Y. Infectome: a platform to trace infectious triggers of autoimmunity. Autoimmun Rev. 2013 May;12(7):726-40. doi: 10.1016/j.autrev.2012.12.005. Epub 2012 Dec 22. Review. PubMed PMID: 23266520. 57: Smyk DS, Bogdanos DP, Pares A, Liaskos C, Billinis C, Burroughs AK, Rigopoulou EI. Tuberculosis is not a risk factor for primary biliary cirrhosis: a review of the literature. Tuberc Res Treat. 2012;2012:218183. doi: 10.1155/2012/218183. Epub 2012 Oct 30. PubMed PMID: 23213506; PubMed Central PMCID: PMC3504403.

58: Mavropoulos A, Orfanidou T, Liaskos C, Smyk DS, Billinis C, Blank M, Rigopoulou EI, Bogdanos DP. p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: lessons to learn from ANCA vasculitis and pemphigus vulgaris. Autoimmun Rev. 2013 Mar;12(5):580-90. doi: 10.1016/j.autrev.2012.10.019. Epub 2012 Nov 30. Review. PubMed PMID: 23207287. 59: Ehser J, Holdener M, Christen S, Bayer M, Pfeilschifter JM, Hintermann E, Bogdanos DP, Christen U. Molecular mimicry rather than identity breaks T-cell tolerance in the CYP2D6 mouse model for human autoimmune hepatitis. J Autoimmun. 2013 May;42:39-49. doi: 10.1016/j.jaut.2012.11.001. Epub 2012 Nov 28. PubMed PMID: 23200317. 60: Smyk DS, Rigopoulou EI, Bogdanos DP. Potential Roles for Infectious Agents in the Pathophysiology of Primary Biliary Cirrhosis: What's New? Curr Infect Dis Rep. 2013 Feb;15(1):14-24. doi: 10.1007/s11908-012-0304-2. PubMed PMID: 23188623.

61: Smyk DS, Bogdanos DP, Mytilinaiou MG, Burroughs AK, Rigopoulou EI. Rheumatoid arthritis and primary biliary cirrhosis: cause, consequence, or coincidence? Arthritis. 2012;2012:391567. doi: 10.1155/2012/391567. Epub 2012 Oct 24. PubMed PMID: 23150824; PubMed Central PMCID: PMC3488395. 62: Kempinska-Podhorodecka A, Shums Z, Wasilewicz M, Wunsch E, Milkiewicz M, Bogdanos DP, Norman GL, Milkiewicz P. TRAF1 gene polymorphism correlates with the titre of Gp210 antibody in patients with primary biliary cirrhosis. Clin Dev Immunol. 2012;2012:487521. doi: 10.1155/2012/487521. Epub 2012 Oct 22. PubMed PMID: 23125866; PubMed Central PMCID: PMC3485529.

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63: Pavlidis P, Romanidou O, Roggenbuck D, Mytilinaiou MG, Al-Sulttan F, Liaskos C, Smyk DS, Koutsoumpas AL, Rigopoulou EI, Conrad K, Forbes A, Bogdanos DP. Ileal inflammation may trigger the development of GP2-specific pancreatic autoantibodies in patients with Crohn's disease. Clin Dev Immunol. 2012;2012:640835. doi: 10.1155/2012/640835. Epub 2012 Oct 17. PubMed PMID: 23118780; PubMed Central PMCID: PMC3483735. 64: Bogdanos DP, Gershwin ME. What is new in primary biliary cirrhosis? Dig Dis. 2012;30 Suppl 1:20-31. doi: 10.1159/000341118. Epub 2012 Oct 11. Review. PubMed PMID: 23075865. 65: Roggenbuck D, Humbel RL, Reinhold D, Bogdanos DP, Conrad K, Laass MW. Glycoprotein 2 antibodies in inflammatory bowel disease: no association with disease phenotype? J Pediatr Gastroenterol Nutr. 2013 Jan;56(1):e5. doi: 10.1097/MPG.0b013e318275fa77. PubMed PMID: 23059646.

66: Smyk D, Rigopoulou EI, Zen Y, Abeles RD, Billinis C, Pares A, Bogdanos DP. Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis? World J Gastroenterol. 2012 Sep 21;18(35):4855-65. Review. PubMed PMID: 23002357; PubMed Central PMCID: PMC3447267. 67: Smyk DS, Rigopoulou EI, Pares A, Mytilinaiou MG, Invernizzi P, Bogdanos DP. Familial primary biliary cirrhosis: like mother, like daughter? Acta Gastroenterol Belg. 2012 Jun;75(2):203-9. Review. PubMed PMID: 22870783. 68: Bogdanos DP, Roggenbuck D, Reinhold D, Wex T, Pavlidis P, von Arnim U, Malfertheiner P, Forbes A, Conrad K, Laass MW. Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease. BMC Gastroenterol. 2012 Aug 6;12:102. PubMed PMID: 22866900; PubMed Central PMCID: PMC3449192. 69: Smyk DS, Rigopoulou EI, Koutsoumpas AL, Kriese S, Burroughs AK, Bogdanos DP.

Autoantibodies in autoimmune pancreatitis. Int J Rheumatol. 2012;2012:940831. doi: 10.1155/2012/940831. Epub 2012 Jul 12. PubMed PMID: 22844291; PubMed Central PMCID: PMC3403403. 70: Invernizzi P, Alessio MG, Smyk DS, Lleo A, Sonzogni A, Fabris L, Candusso M, Bogdanos DP, Iorio R, Torre G. Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and review of the literature. BMC Gastroenterol. 2012 Jul 20;12:92. doi: 10.1186/1471-230X-12-92. Review. PubMed PMID: 22816667; PubMed Central PMCID: PMC3464927. 71: Smyk DS, Rigopoulou EI, Pares A, Billinis C, Burroughs AK, Muratori L, Invernizzi P, Bogdanos DP. Sex differences associated with primary biliary cirrhosis. Clin Dev Immunol. 2012;2012:610504. doi: 10.1155/2012/610504. Epub 2012 May 30. Review. PubMed PMID: 22693524; PubMed Central PMCID: PMC3369468.

72: Rigopoulou EI, Smyk DS, Matthews CE, Billinis C, Burroughs AK, Lenzi M, Bogdanos DP. Epstein-barr virus as a trigger of autoimmune liver diseases. Adv Virol. 2012;2012:987471. doi: 10.1155/2012/987471. Epub 2012 May 28. PubMed PMID: 22693505; PubMed Central PMCID: PMC3368154. 73: Rigopoulou EI, Roggenbuck D, Smyk DS, Liaskos C, Mytilinaiou MG, Feist E, Conrad K, Bogdanos DP. Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: lost and found. Autoimmun Rev. 2012 Dec;12(2):260-9. doi: 10.1016/j.autrev.2012.04.005. Epub 2012 May 1. Review. PubMed PMID: 22571878. 74: Mytilinaiou MG, Meyer W, Scheper T, Rigopoulou EI, Probst C, Koutsoumpas AL,

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Abeles D, Burroughs AK, Komorowski L, Vergani D, Bogdanos DP. Diagnostic and clinical utility of antibodies against the nuclear body promyelocytic leukaemia and Sp100 antigens in patients with primary biliary cirrhosis. Clin Chim Acta. 2012 Aug 16;413(15-16):1211-6. doi: 10.1016/j.cca.2012.03.020. Epub 2012 Apr 3. PubMed PMID: 22503841. 75: Duarte-Rey C, Bogdanos DP, Yang CY, Roberts K, Leung PS, Anaya JM, Worman HJ, Gershwin ME. Primary biliary cirrhosis and the nuclear pore complex. Autoimmun Rev. 2012 Oct;11(12):898-902. doi: 10.1016/j.autrev.2012.03.005. Epub 2012 Apr 1. Review. PubMed PMID: 22487189; PubMed Central PMCID: PMC3396748. 76: Smyk DS, Mytilinaiou MG, Milkiewicz P, Rigopoulou EI, Invernizzi P, Bogdanos DP. Towards systemic sclerosis and away from primary biliary cirrhosis: the case of PTPN22. Auto Immun Highlights. 2011 Sep 7;3(1):1-9. doi: 10.1007/s13317-011-0023-y. eCollection 2012 Apr. Review. PubMed PMID: 26000122; PubMed Central PMCID: PMC4389021.

77: Rigamonti C, Bogdanos DP, Mytilinaiou MG, Smyk DS, Rigopoulou EI, Burroughs AK. Primary biliary cirrhosis associated with systemic sclerosis: diagnostic and clinical challenges. Int J Rheumatol. 2011;2011:976427. doi: 10.1155/2011/976427. Epub 2011 Dec 6. PubMed PMID: 22187566; PubMed Central PMCID: PMC3236477. 78: Duarte-Rey C, Bogdanos DP, Leung PS, Anaya JM, Gershwin ME. IgM predominance in autoimmune disease: genetics and gender. Autoimmun Rev. 2012 May;11(6-7):A404-12. doi: 10.1016/j.autrev.2011.12.001. Epub 2011 Dec 8. Review. PubMed PMID: 22178509. 79: Bogdanos DP, Smyk DS, Rigopoulou EI, Mytilinaiou MG, Heneghan MA, Selmi C, Gershwin ME. Twin studies in autoimmune disease: genetics, gender and environment. J Autoimmun. 2012 May;38(2-3):J156-69. doi: 10.1016/j.jaut.2011.11.003. Epub 2011 Dec 15. Review. PubMed PMID: 22177232.

80: Smyk DS, Rigopoulou EI, Muratori L, Burroughs AK, Bogdanos DP. Smoking as a risk factor for autoimmune liver disease: what we can learn from primary biliary cirrhosis. Ann Hepatol. 2012 Jan-Feb;11(1):7-14. Review. PubMed PMID: 22166556. 81: Zen Y, Bogdanos DP, Kawa S. Type 1 autoimmune pancreatitis. Orphanet J Rare Dis. 2011 Dec 7;6:82. doi: 10.1186/1750-1172-6-82. Review. PubMed PMID: 22151922; PubMed Central PMCID: PMC3261813. 82: Smyk DS, Rigopoulou EI, Lleo A, Abeles RD, Mavropoulos A, Billinis C, Invernizzi P, Bogdanos DP. Immunopathogenesis of primary biliary cirrhosis: an old wives' tale. Immun Ageing. 2011 Dec 2;8(1):12. doi: 10.1186/1742-4933-8-12. PubMed PMID: 22136162; PubMed Central PMCID: PMC3238302. 83: Mavropoulos A, Smyk D, Rigopoulou EI, Bogdanos DP. Human peripheral blood mononuclear cell culture for flow cytometric analysis of phosphorylated mitogen-activated protein kinases. Methods Mol Biol. 2012;806:275-85. doi:

10.1007/978-1-61779-367-7_19. PubMed PMID: 22057459. 84: Bogdanos DP, Rigopoulou EI, Smyk DS, Roggenbuck D, Reinhold D, Forbes A, Laass MW, Conrad K. Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies. Autoimmun Rev. 2011 Dec;11(2):143-8. doi: 10.1016/j.autrev.2011.09.004. Epub 2011 Sep 29. Review. PubMed PMID: 21983481. 85: Smyk DS, Bogdanos DP, Kriese S, Billinis C, Burroughs AK, Rigopoulou EI. Urinary tract infection as a risk factor for autoimmune liver disease: from bench to bedside. Clin Res Hepatol Gastroenterol. 2012 Apr;36(2):110-21. doi:

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10.1016/j.clinre.2011.07.013. Epub 2011 Sep 8. Review. PubMed PMID: 21907008. 86: Smyk D, Cholongitas E, Kriese S, Rigopoulou EI, Bogdanos DP. Primary biliary cirrhosis: family stories. Autoimmune Dis. 2011;2011:189585. doi: 10.4061/2011/189585. Epub 2011 May 5. PubMed PMID: 21687641; PubMed Central PMCID: PMC3112499. 87: Smyk D, Grammatikopoulos T, Daponte A, Rigopoulou EI, Bogdanos DP. Fetomaternal alloimmunity as a cause of liver disease. Auto Immun Highlights. 2011 Mar 23;2(1):21-8. doi: 10.1007/s13317-011-0019-7. eCollection 2011 May. Review. PubMed PMID: 26000116; PubMed Central PMCID: PMC4389071. 88: Koutsoumpas A, Polymeros D, Tsiamoulos Z, Smyk D, Karamanolis G, Triantafyllou K, Rigopoulou EI, Forbes A, Vergani D, Bogdanos DP, Ladas SD. Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease. J Crohns Colitis. 2011 Apr;5(2):101-9. doi:

10.1016/j.crohns.2010.10.009. Epub 2010 Dec 3. PubMed PMID: 21453878. 89: Smyk D, Rigopoulou EI, Baum H, Burroughs AK, Vergani D, Bogdanos DP. Autoimmunity and environment: am I at risk? Clin Rev Allergy Immunol. 2012 Apr;42(2):199-212. doi: 10.1007/s12016-011-8259-x. Review. PubMed PMID: 21337133. 90: Pavlidis P, Forbes A, Bogdanos DP. Antibodies to glycoprotein 2 (GP2) in patients with inflammatory bowel diseases from UK. Clin Chim Acta. 2011 May 12;412(11-12):1163-4. doi: 10.1016/j.cca.2011.02.005. Epub 2011 Feb 15. PubMed PMID: 21329686. 91: Smyk D, Mytilinaiou MG, Rigopoulou EI, Bogdanos DP. PBC triggers in water reservoirs, coal mining areas and waste disposal sites: from Newcastle to New York. Dis Markers. 2010;29(6):337-44. doi: 10.3233/DMA-2010-0744. Review. PubMed PMID: 21297253; PubMed Central PMCID: PMC3835285.

92: Bogdanos DP, Baum H, Vergani D, Burroughs AK. The role of E. coli infection

in the pathogenesis of primary biliary cirrhosis. Dis Markers. 2010;29(6):301-11.

doi: 10.3233/DMA-2010-0745. Review. PubMed PMID: 21297249; PubMed Central PMCID:

PMC3835537.

93: Roggenbuck D, Reinhold D, Wex T, Goihl A, von Arnim U, Malfertheiner P, Büttner T, Porstmann T, Porstmann S, Liedvogel B, Bogdanos DP, Laass MW, Conrad K. Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease. Clin Chim Acta. 2011 Apr 11;412(9-10):718-24. doi: 10.1016/j.cca.2010.12.029. Epub 2010 Dec 31. PubMed PMID: 21195704. 94: Bogdanos DP, Komorowski L. Disease-specific autoantibodies in primary biliary cirrhosis. Clin Chim Acta. 2011 Mar 18;412(7-8):502-12. doi: 10.1016/j.cca.2010.12.019. Epub 2010 Dec 23. Review. PubMed PMID: 21185272.

95: Liu H, Norman GL, Shums Z, Worman HJ, Krawitt EL, Bizzaro N, Vergani D, Bogdanos DP, Dalekos GN, Milkiewicz P, Czaja AJ, Heathcote EJ, Hirschfield GM, Tan EM, Miyachi K, Bignotto M, Battezzati PM, Lleo A, Leung PS, Podda M, Gershwin ME, Invernizzi P. PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis. J Autoimmun. 2010 Dec;35(4):436-42. doi: 10.1016/j.jaut.2010.09.005. Epub 2010 Oct 6. PubMed PMID: 20932720. 96: Koutsoumpas A, Mytilinaiou M, Polymeros D, Dalekos GN, Bogdanos DP. Anti-Helicobacter pylori antibody responses specific for VacA do not trigger primary biliary cirrhosis-specific antimitochondrial antibodies. Eur J

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Gastroenterol Hepatol. 2009 Oct;21(10):1220. doi: 10.1097/MEG.0b013e32831a4807. PubMed PMID: 19749508. 97: Bogdanos DP, Mieli-Vergani G, Vergani D. Autoantibodies and their antigens in autoimmune hepatitis. Semin Liver Dis. 2009 Aug;29(3):241-53. doi: 10.1055/s-0029-1233533. Epub 2009 Aug 12. Review. PubMed PMID: 19675997. 98: Mytilinaiou MG, Bogdanos DP. Primary biliary cirrhosis-specific autoantibodies in patients with systemic sclerosis. Dig Liver Dis. 2009 Dec;41(12):916; author reply 916-7. doi: 10.1016/j.dld.2009.05.005. Epub 2009 Jul 14. PubMed PMID: 19604733. 99: Vergani D, Longhi MS, Bogdanos DP, Ma Y, Mieli-Vergani G. Autoimmune hepatitis. Semin Immunopathol. 2009 Sep;31(3):421-35. doi: 10.1007/s00281-009-0170-7. Epub 2009 Jun 17. Review. PubMed PMID: 19533129.

100: Dähnrich C, Pares A, Caballeria L, Rosemann A, Schlumberger W, Probst C, Mytilinaiou M, Bogdanos DP, Vergani D, Stöcker W, Komorowski L. New ELISA for detecting primary biliary cirrhosis-specific antimitochondrial antibodies. Clin Chem. 2009 May;55(5):978-85. doi: 10.1373/clinchem.2008.118299. Epub 2009 Mar 5. PubMed PMID: 19264849. 101: Bogdanos DP, Dalekos GN. Enzymes as target antigens of liver-specific autoimmunity: the case of cytochromes P450s. Curr Med Chem. 2008;15(22):2285-92. Review. PubMed PMID: 18781950. 102: Bogdanos DP, Pusl T, Rust C, Vergani D, Beuers U. Primary biliary cirrhosis following Lactobacillus vaccination for recurrent vaginitis. J Hepatol. 2008 Sep;49(3):466-73. doi: 10.1016/j.jhep.2008.05.022. Epub 2008 Jun 25. PubMed PMID: 18644655. 103: Bogdanos DP, Invernizzi P, Mackay IR, Vergani D. Autoimmune liver serology:

current diagnostic and clinical challenges. World J Gastroenterol. 2008 Jun 7;14(21):3374-87. Review. PubMed PMID: 18528935; PubMed Central PMCID: PMC2716592. 104: Bogdanos DP, Vergani D. Bacteria and primary biliary cirrhosis. Clin Rev Allergy Immunol. 2009 Feb;36(1):30-9. doi: 10.1007/s12016-008-8087-9. Review. PubMed PMID: 18498061. 105: Granito A, Stanzani M, Muratori L, Bogdanos DP, Muratori P, Pappas G, Quarneti C, Lenzi M, Vergani D, Bianchi FB. LKM1-positive type 2 autoimmune hepatitis following allogenic hematopoietic stem-cell transplantation. Am J Gastroenterol. 2008 May;103(5):1313-4. doi: 10.1111/j.1572-0241.2007.01782_7.x. PubMed PMID: 18477361. 106: Dalekos GN, Bogdanos DP, Neuberger J. Celiac disease-related autoantibodies in end-stage autoimmune liver diseases: what is the message? Liver Int. 2008

Apr;28(4):426-8. doi: 10.1111/j.1478-3231.2008.01708.x. PubMed PMID: 18339068. 107: Bernal W, Meda F, Ma Y, Bogdanos DP, Vergani D. Disease-specific autoantibodies in patients with acute liver failure: the King's College London Experience. Hepatology. 2008 Mar;47(3):1096-7; author reply 1097. doi: 10.1002/hep.22179. PubMed PMID: 18306217. 108: Rigopoulou EI, Davies ET, Bogdanos DP, Liaskos C, Mytilinaiou M, Koukoulis GK, Dalekos GN, Vergani D. Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis. Liver Int. 2007 Nov;27(9):1226-31. PubMed PMID: 17919234.

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109: Longhi MS, Hussain MJ, Bogdanos DP, Quaglia A, Mieli-Vergani G, Ma Y, Vergani D. Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2. Hepatology. 2007 Aug;46(2):472-84. PubMed PMID: 17559153. 110: Bogdanos DP, Liaskos C, Pares A, Norman G, Rigopoulou EI, Caballeria L, Dalekos GN, Rodes J, Vergani D. Anti-gp210 antibody mirrors disease severity in primary biliary cirrhosis. Hepatology. 2007 Jun;45(6):1583; author reply 1583-4. PubMed PMID: 17538935. 111: Rigopoulou EI, Bogdanos DP, Liaskos C, Koutsoumpas A, Baum H, Vergani D, Dalekos GN. Anti-mitochondrial antibody immunofluorescent titres correlate with the number and intensity of immunoblot-detected mitochondrial bands in patients with primary biliary cirrhosis. Clin Chim Acta. 2007 May 1;380(1-2):118-21. Epub 2007 Feb 1. PubMed PMID: 17321509.

112: Liaskos C, Bogdanos DP, Rigopoulou EI, Dalekos GN. Development of antimitochondrial antibodies in patients with autoimmune hepatitis: art of facts or an artifact? J Gastroenterol Hepatol. 2007 Mar;22(3):454-5. PubMed PMID: 17295788. 113: Rigopoulou EI, Dalekos G, Bogdanos DP. How common are connective tissue disorders in patients with autoimmune hepatitis? Semin Arthritis Rheum. 2007 Apr;36(5):332; author reply 333. Epub 2007 Feb 5. PubMed PMID: 17276497. 114: Liaskos C, Bogdanos DP, Davies ET, Dalekos GN. Diagnostic relevance of anti-filamentous actin antibodies in autoimmune hepatitis. J Clin Pathol. 2007 Jan;60(1):107-8. PubMed PMID: 17213359; PubMed Central PMCID: PMC1860582. 115: Bogdanos DP, Rigopoulou EI. Viral/self-mimicry and immunological cross-reactivity as a trigger of hepatic C virus associated autoimmune diabetes.

Diabetes Res Clin Pract. 2007 Jul;77(1):155-6. Epub 2006 Nov 21. PubMed PMID: 17118481. 116: Mullighan CG, Bogdanos DP, Vergani D, Bardy PG. Cytochrome P450 1A2 is a target antigen in hepatitic graft-versus-host disease. Bone Marrow Transplant. 2006 Nov;38(10):703-5. Epub 2006 Sep 25. PubMed PMID: 17001344. 117: Bogdanos DP, Koutsoumpas A, Baum H, Vergani D. Borrelia Burgdorferi: a new self-mimicking trigger in primary biliary cirrhosis. Dig Liver Dis. 2006 Oct;38(10):781-2; author reply 782-3. Epub 2006 Jul 25. PubMed PMID: 16870516. 118: Bogdanos DP, Vergani D. Origin of cross-reactive autoimmunity in primary biliary cirrhosis. Liver Int. 2006 Aug;26(6):633-5. Review. PubMed PMID: 16842317. 119: Polymeros D, Bogdanos DP, Day R, Arioli D, Vergani D, Forbes A. Does

cross-reactivity between mycobacterium avium paratuberculosis and human intestinal antigens characterize Crohn's disease? Gastroenterology. 2006 Jul;131(1):85-96. PubMed PMID: 16831593. 120: Bogdanos DP, Rigopoulou EI. Self-mimicking autoimmune domains of hepatitis C virus core antigen. Vaccine. 2006 Sep 11;24(37-39):6173-4. Epub 2006 Jun 9. PubMed PMID: 16806599. 121: Bogdanos DP, Liaskos C, Rigopoulou EI, Dalekos GN. Anti-mitochondrial antibodies in patients with systemic lupus erythematosus: revealing the unforeseen. Clin Chim Acta. 2006 Nov;373(1-2):183-4; author reply 185. Epub 2006

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Apr 7. PubMed PMID: 16714006. 122: Ma Y, Bogdanos DP, Hussain MJ, Underhill J, Bansal S, Longhi MS, Cheeseman P, Mieli-Vergani G, Vergani D. Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2. Gastroenterology. 2006 Mar;130(3):868-82. PubMed PMID: 16530525. 123: Bogdanos DP, Smith H, Ma Y, Baum H, Mieli-Vergani G, Vergani D. A study of molecular mimicry and immunological cross-reactivity between hepatitis B surface antigen and myelin mimics. Clin Dev Immunol. 2005 Sep;12(3):217-24. PubMed PMID: 16295528; PubMed Central PMCID: PMC2275415. 124: Bogdanos DP, Baum H, Okamoto M, Montalto P, Sharma UC, Rigopoulou EI, Vlachogiannakos J, Ma Y, Burroughs AK, Vergani D. Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic. Hepatology. 2005 Aug;42(2):458-65.

PubMed PMID: 16025495. 125: Longhi MS, Ma Y, Mitry RR, Bogdanos DP, Heneghan M, Cheeseman P, Mieli-Vergani G, Vergani D. Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis. J Autoimmun. 2005 Aug;25(1):63-71. PubMed PMID: 16005184. 126: Muratori L, Bogdanos DP, Muratori P, Lenzi M, Granito A, Ma Y, Mieli-Vergani G, Bianchi FB, Vergani D. Susceptibility to thyroid disorders in hepatitis C. Clin Gastroenterol Hepatol. 2005 Jun;3(6):595-603. PubMed PMID: 15952102. 127: Rigopoulou EI, Davies ET, Pares A, Zachou K, Liaskos C, Bogdanos DP, Rodes J, Dalekos GN, Vergani D. Prevalence and clinical significance of isotype specific antinuclear antibodies in primary biliary cirrhosis. Gut. 2005 Apr;54(4):528-32. PubMed PMID: 15753539; PubMed Central PMCID: PMC1774444.

128: Bogdanos DP, Mieli-Vergani G, Vergani D. Non-organ-specific autoantibodies in hepatitis C virus infection: do they matter? Clin Infect Dis. 2005 Feb 15;40(4):508-10. Epub 2005 Jan 21. PubMed PMID: 15712071. 129: Ma Y, Meregalli M, Hodges S, Davies N, Bogdanos DP, Fargion S, Fiorelli G, Vergani D. Alcohol dehydrogenase: an autoantibody target in patients with alcoholic liver disease. Int J Immunopathol Pharmacol. 2005 Jan-Mar;18(1):173-82. PubMed PMID: 15698522. 130: Bogdanos DP, Gilbert D, Bianchi I, Leoni S, Mitry RR, Ma Y, Mieli-Vergani G, Vergani D. Antibodies to soluble liver antigen and alpha-enolase in patients with autoimmune hepatitis. J Autoimmune Dis. 2004 Nov 19;1(1):4. PubMed PMID: 15679947; PubMed Central PMCID: PMC546408. 131: Bogdanos DP, Baum H, Gunsar F, Arioli D, Polymeros D, Ma Y, Burroughs AK, Vergani D. Extensive homology between the major immunodominant mitochondrial

antigen in primary biliary cirrhosis and Helicobacter pylori does not lead to immunological cross-reactivity. Scand J Gastroenterol. 2004 Oct;39(10):981-7. PubMed PMID: 15513338. 132: Longhi MS, Ma Y, Bogdanos DP, Cheeseman P, Mieli-Vergani G, Vergani D. Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease. J Hepatol. 2004 Jul;41(1):31-7. PubMed PMID: 15246204. 133: Bogdanos DP, Mieli-Vergani G, Vergani D. Non-organ-specific autoantibodies in children with chronic hepatitis C virus infection. Clin Infect Dis. 2004 May 15;38(10):1505; author reply 1505-6. PubMed PMID: 15156495.

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134: Bogdanos DP, Vergani D, Muratori P, Muratori L, Bianchi FB. Specificity of anti-sp100 antibody for primary biliary cirrhosis. Scand J Gastroenterol. 2004 Apr;39(4):405-6; author reply 407. PubMed PMID: 15125479. 135: Bogdanos DP, Pares A, Baum H, Caballeria L, Rigopoulou EI, Ma Y, Burroughs AK, Rodes J, Vergani D. Disease-specific cross-reactivity between mimicking peptides of heat shock protein of Mycobacterium gordonae and dominant epitope of E2 subunit of pyruvate dehydrogenase is common in Spanish but not British patients with primary biliary cirrhosis. J Autoimmun. 2004 Jun;22(4):353-62. PubMed PMID: 15120760. 136: Bogdanos DP, Pares A, Rodés J, Vergani D. Primary biliary cirrhosis specific antinuclear antibodies in patients from Spain. Am J Gastroenterol. 2004 Apr;99(4):763-4; author reply 765. PubMed PMID: 15089915. 137: Bogdanos DP, Lenzi M, Okamoto M, Rigopoulou EI, Muratori P, Ma Y, Muratori

L, Tsantoulas D, Mieli- Vergani G, Bianchi FB, Vergani D. Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51. Int J Immunopathol Pharmacol. 2004 Jan-Apr;17(1):83-92. PubMed PMID: 15000871. 138: Bogdanos DP, Bianchi I, Ma Y, Mitry RR, Mieli-Vergani G, Vergani D. Targets of antibodies to soluble liver antigen in patients with autoimmune hepatitis. Clin Chem. 2004 Mar;50(3):682-3; author reply 683-4. PubMed PMID: 14981048. 139: Vergani D, Bogdanos DP, Baum H. Unusual suspects in primary biliary cirrhosis. Hepatology. 2004 Jan;39(1):38-41. Review. PubMed PMID: 14752820. 140: Bogdanos DP, Baum H, Butler P, Rigopoulou EI, Davies ET, Ma Y, Burroughs AK, Vergani D. Association between the primary biliary cirrhosis specific anti-sp100 antibodies and recurrent urinary tract infection. Dig Liver Dis. 2003 Nov;35(11):801-5. PubMed PMID: 14674671.

141: Bogdanos DP, Baum H, Grasso A, Okamoto M, Butler P, Ma Y, Rigopoulou E, Montalto P, Davies ET, Burroughs AK, Vergani D. Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. J Hepatol. 2004 Jan;40(1):31-9. PubMed PMID: 14672611. 142: Bogdanos DP, Baum H, Vergani D. Antimitochondrial and other autoantibodies. Clin Liver Dis. 2003 Nov;7(4):759-77, vi. Review. PubMed PMID: 14594130. 143: Bogdanos DP, McFarlane IG. Cytochrome P450 2A6 meets P450 2D6: an enigma of viral infections and autoimmunity. J Hepatol. 2003 Nov;39(5):860-3. Review. PubMed PMID: 14568272. 144: Gregorio GV, Choudhuri K, Ma Y, Pensati P, Iorio R, Grant P, Garson J, Bogdanos DP, Vegnente A, Mieli-Vergani G, Vergani D. Mimicry between the hepatitis C virus polyprotein and antigenic targets of nuclear and smooth muscle

antibodies in chronic hepatitis C virus infection. Clin Exp Immunol. 2003 Sep;133(3):404-13. PubMed PMID: 12930368; PubMed Central PMCID: PMC1808793. 145: Hannam S, Bogdanos DP, Davies ET, Hussain MJ, Portmann BC, Mieli-Vergani G, Vergani D. Neonatal liver disease associated with placental transfer of anti-mitochondrial antibodies. Autoimmunity. 2002 Dec;35(8):545-50. PubMed PMID: 12765481. 146: Vergani D, Bogdanos DP. Positive markers in AMA-negative PBC. Am J Gastroenterol. 2003 Feb;98(2):241-3. PubMed PMID: 12591035.

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147: Kerkar N, Choudhuri K, Ma Y, Mahmoud A, Bogdanos DP, Muratori L, Bianchi F, Williams R, Mieli-Vergani G, Vergani D. Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease. J Immunol. 2003 Feb 1;170(3):1481-9. PubMed PMID: 12538711. 148: Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G. Pathogenesis of autoimmune hepatitis. Clin Liver Dis. 2002 Aug;6(3):727-37. Review. PubMed PMID: 12362577. 149: Ma Y, Thomas MG, Okamoto M, Bogdanos DP, Nagl S, Kerkar N, Lopes AR, Muratori L, Lenzi M, Bianchi FB, Mieli-Vergani G, Vergani D. Key residues of a major cytochrome P4502D6 epitope are located on the surface of the molecule. J Immunol. 2002 Jul 1;169(1):277-85. PubMed PMID: 12077255. 150: Wen L, Ma Y, Bogdanos DP, Wong FS, Demaine A, Mieli-Vergani G, Vergani D.

Pediatric autoimmune liver diseases: the molecular basis of humoral and cellular immunity. Curr Mol Med. 2001 Jul;1(3):379-89. Review. PubMed PMID: 11899084. 151: Ma Y, Okamoto M, Thomas MG, Bogdanos DP, Lopes AR, Portmann B, Underhill J, Dürr R, Mieli-Vergani G, Vergani D. Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease. Hepatology. 2002 Mar;35(3):658-64. PubMed PMID: 11870381. 152: Bogdanos DP, Baum H, Sharma UC, Grasso A, Ma Y, Burroughs AK, Vergani D. Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis. J Hepatol. 2002 Jan;36(1):14-21. PubMed PMID: 11804659. 153: Bogdanos DP, Mieli-Vergani G, Vergani D. Liver-kidney microsomal antibody-positive autoimmune hepatitis in the United States. Am J Gastroenterol. 2001 Dec;96(12):3447-8. PubMed PMID: 11774973.

154: Bogdanos DP, Choudhuri K, Vergani D. Molecular mimicry and autoimmune liver disease: virtuous intentions, malign consequences. Liver. 2001 Aug;21(4):225-32. Review. PubMed PMID: 11454184. 155: Baum H, Bogdanos DP, Vergani D. Antibodies to Clp protease in primary biliary cirrhosis: possible role of a mimicking T-cell epitope. J Hepatol. 2001 May;34(5):785-7. PubMed PMID: 11434633. 156: Bogdanos DP, Mieli-Vergani G, Vergani D. Virus, liver and autoimmunity. Dig Liver Dis. 2000 Jun-Jul;32(5):440-6. PubMed PMID: 11030191. 157: Bogdanos DP, Muratori L, Bianchi FB, Vergani D. Hepatitis C virus and autoimmunity. Hepatology. 2000 Jun;31(6):1380. PubMed PMID: 10866525.

Additional Publications not deposited in Pubmed

158: Mavropoulos A, Koutsoumpas A, Bogdanos DP, Sakkas LI. The role of p38 MAP in autoimmune diseases. Inter Trends Immun 2014; 3(2) 2015, 1-17 160: Smyk DS, Bogdanos DP, Rigopoulou EI. Risk factors for autoimmune hepatitis. From genes and pregnancy to vaccination and pollutants. Immuno-Gastroenterology 2013, 2(1); 29-37

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161: Roggenbuck D, Reinhold D, Wex T, von Arnim U, Malfertheiner P, Sturn A, Werner L, Bogdanos DP, Laass MW, Conrad K. The Authors’ reply. Gut 2012 61: 164-165; doi: 10.1136/gut.2010.237214 162: Smyk DS, Rigopouloy EI, Zen Y, Koutsoumpas A, Baum H, Bogdanos DP. Infectious triggers of primary biliary cirrhosis: do we know enough? Curr Trends Immunol 2010 11: 35-49

163: Bogdanos DP, Christen U. Autoimmune hepatitis: an update on current animal models.The Open Pathology Journal 2008;2:39-45 164: Bogdanos DP, Vergani D, Mieli-Vergani G. Overlap syndromes from pediatrics to adulthood. J Gastroenterol Hepatol 2004;19:S284-6

Chapters in Books

165: Bogdanos DP, Smyk DS, Sakkas LI, Shoenfeld Y. Chapter 9: Infection and

Autoimmunity, 2nd edition, Y Shoenfeld, N Agmon-Levin, N Rose, 01/2015:: pp149-162; Academic Press, 2015

166: Bogdanos DP, Leung PSC, Gershwin ME. Chapter 87: Liver and biliary tract. In Mucosal Immunology 4th Edition, Vol 2 Editors Jiri Mestecky, Warren Strober, Michael W. Russell, Brian L. Kelsall, Hide Cheroutre, Bart Lambrecht, pp 1695-1717, Academic Press, 2015

167: Smyk DS, Sakkas LI, Shoenfeld Y, Bogdanos DP. Hepatitis B Vaccination and Autoimmunity in Vaccines and autoimmunity, pp.147-162 Editors: Yehuda Shoenfeld, Nancy Agmon-Levin, Lucija Tomljenovic Publisher: Wiley-Blackwell, Oxford 2014

168: Antico A, Tampoia M, Bogdanos D, Tozzolli R. Gastric autoantibodies. pp 359-364. In Autoantibodies 3rd Edition. Editors: Y Shoenfeld, PL Meroni, ME Gershwin. Elsevier, Oxford, 2014

169: Conrad K, Bogdanos D, Roggenbuck D. Antipancreatic antibodies.Chapter 51, pp.433-440. In Autoantibodies 3rd Edition. Editors: Y Shoenfeld, PL Meroni, ME Gershwin. Elsevier, Oxford, 2014

170: Bogdanos DP, Rigamonti C, Milkiewicz P, Rigopoulou EI, Burroughs AK. Emerging issues in the immunopathogenesis, diagnosis and clinical management of primary biliary cirrhosis associated with systemic sclerosis. In ‘Systemic Sclerosis’ Editor: T. Radstake; Publishers: Intech; ISBN 978-953-307-869-4, 2011

171: Bogdanos DP, Conrad K, Smyk DS, Rigopoulou EI, Forbes A. Novel autoantibody markers in autoimmune gastrointestinal and liver diseases. pp288-301 Editors K. Conrad, Pabst Science Publishers, Lengerich, Germany, 2011 From Prediction to Prevention of Autoimmune Diseases. by K. Conrad, E. K. L. Chan, M. J. Fritzler, R.L. Humbel, P. L. Meroni, Y. Shoenfeld (Eds.)

172. L. Komorowski, D.P Bogdanos, C. Probst, C. Dähnrich, A. Rosemann, W. Schlumberger, W. Stöcker: Detection of primary biliary cirrhosis-associated anti-mitochondrial antibodies using an improved test system: Anti-M2/BPO ELISA. From Etiopathogenesis to the Prediction of Autoimmune Diseases: Relevance of

Autoantibodies Chapter 6.2 Gastrointestinal and Liver Diseases (in press) K. Conrad, E.K.L. Chan, M.J. Fritzler, U. Sack, Y. Shoenfeld, A.S. Wiik (Eds.)

173. W. Meyer, T. Scheper, N. Janssen, L. Komorowski, C. Probst, W. Schlumberger, D.P Bogdanos, W. Stöcker: A comprehensive line immunoassay for the detection of autoantibodies in primary biliary cirrhosis (PBC) From Etiopathogenesis to the Prediction of Autoimmune Diseases: Relevance of Autoantibodies Chapter 6.2 Gastrointestinal and Liver Diseases K. Conrad, E.K.L. Chan, M.J. Fritzler, U. Sack, Y. Shoenfeld, A.S. Wiik (Eds.) Pabst Science Publishers, Lengerich, Germany

174. Ma Y, Longhi MS, Bogdanos DP, Mieli-Vergani G, Vergani D. Autoreactive T cells: any evidence in autoimmune liver disease? In “Autoimmune liver Diseases”. Falk Symposium 142, Kluwer Academic Publishers, Dordrecht, pages 49-58, 2004

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175. Bogdanos DP, Baum H, Vergani D. Antimitochondrial and other autoantibodies. In “Primary biliary cirrhosis”. Gitlin N, Heathcote EJ, Eds. Saunders, Philadelphia, USA. Pages 759-77, 2003

176. Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G. (2002) Role of molecular mimicry in viral and autoimmune Liver Disease. In “Autoimmune diseases in pediatric gastroenterology ". Branski D, Hadziselimovic F, Harms K, Lentze M, Eds. Kluwer Academic Publishers, Dordrecht. Pages 9-12, 2002

177. Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G. Pathogenesis of autoimmune hepatitis. In “Autoimmune hepatitis ". Gitlin N, Czaja A, Eds. Saunders, Philadelphia, USA. Pages 439-50, 2002

Publication in Hellenic Journals 178 ΣΑΚΚΑΣ ΛΙ, ΜΑΥΡΟΠΟΥΛΟΣ Α, ΜΠΟΓΔΑΝΟΣ ΔΠ, Meditterranean J Rheumatolog-

Ελληνική Ρευματολογία, Mediterr J Rheumatol 2015; 26(1): 64-67 179. ΡΗΓΟΠΟΥΛΟΥ ΕΙ, ΜΠΟΓΔΑΝΟΣ ΔΠ.Νεότερα δεδομένα στην επιδημιολογία,

παθογένεια και θεραπεία της πρωτοπαθούς χολικής κίρρωσης.Ελληνική Ιατρική

2001;67 (sup1):93-100 179. ΛΑΠΠΑΣ Α, ΜΠΟΓΔΑΝΟΣ Δ, ΚΟΝΣΤΑΝΤΙΝΟΥ Γ, ΜΠΟΚΟΛΑΣ Γ, ΙΩΑΝΝΙΔΗΣ Κ,

ΜΠΟΥΡΑ Π, ΚΟΥΝΤΟΥΡΑΣ Ι. Η αξία της δοκιμασίας ουρεάσης (CLO) σιάλου-οδοντικής πλάκας στην αντιμετώπιση ασθενών με πεπτικό έλκος και Helicobacter pylori λοίμωξη. Αρχεία Ελληνικής Ιατρικής 1997;14:330

Monographies 180. Bogdanos DP. Autoimmune Hepatitis: Confirmation of the diagnosis – Interprenting the Serology. pp.67-92 ‘Autoimmune hepatitis – a guide for practising physicians’ Editors: J Heathcote & G Hirschfield. Humana Press, 2011 181. Bogdanos Dimitrios-Petrou, Molecular mimicry in primary biliary cirrhosis and other hepatic and extra-hepatic diseases: PhD Thesis, Faculty of Medicine, University College London School of Medicine, University of London, May 2005, pages 1-256 Career Metric evolution of Publications in Pubmed At the time I have submitted

1) an application for a non-tenure position of Assistant Professor of Medicine (July 2008), I had published 55 articles deposited in PubMed.

2) At the time I joined the Division of Medicine (September 2011), the total number of publications deposited in PubMed was 72

3) When I submitted my application for the tenure position as an Assistant Professor of Internal Medicine (February 2014), I had published 126 papers listed in PubMed library

4) My current application as an Associate Professor in Internal Medicine and Autoimmune Diseases is supported by 157 articles deposited in Pubmed

BEST IMPACT FACTOR JOURNAL PUBLICATIONS (IF*>6)

1. Gastroenterology (2 articles) 2. Gut (2 articles) 3. Hepatology (7 articles) 4. J of Hepatology (6 articles) 5. American J Gastroenterology (4 articles)

IF: 16.7 IF: 14.7 IF: 11.1 IF: 11.3 IF: 10.8

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6. Clinical Infectious Diseases (2 articles) 7. J Autoimmunity (5 articles) 8. Arthritis & Rheumatology (1 article) 9. Autoimmunity Reviews (8 articles) 10. Clinical Gastroenterology Hepatology (1 article) 11. J Crohn’s Colitis (2 articles)

IF: 8.9 IF: 8.4 IF: 7.8 IF: 7.9 IF: 7.9 IF: 6.2

IF* of 2014

Total number of publications IF>6: 40 Median Journal’s IF of publications with an IF>6: 8.4

Citations Perish or Publish Citations: 5013 Google Scholar Citations: 4928 Scopus Citations: 4008 h-index: 39 (Publish or Perish); 39 (Google Scholar); 37 (Scopus)

MAIN DISTINCTIONS AND AWARDS May 2007

HEFCE CLS Award *Granted by the Higher Education Funding Council for England (HEFCE) to members of academic institutions at an open, national

competition (www.hefce.ac.uk). This was the first time that a Greek scientist was awarded this distinction.

September 2004

Dame Sheila Sherlock Research Medal of the British Association for the Study of the Liver (BASL) 2004 (http://www.basl.org.uk/). *The most prestigious annual award of BASL, awarded for original translational research conducted before attaining the position of

senior lecturer/consultant. This was the first time that a Greek scientist was awarded this medal.

EASL Sheila Sherlock Post-Doc Level Fellowship Award

2012

Supervisor for the research project related to the Award of Dr Vasiliki Gkretsi entitled “The role of integrin-proximal protein complexesduring hepatocellular carcinoma metastasis”

(www.easl.eu).

EASL Sheila Sherlock Short Visting Fellowship Award 2011

Co-Supervisor for the research Award of Dr Rania Romanidou ‘E. coli infection in primary biliary cirrhosis: is there any link?’. Dr Rania Romanidou is a researcher undergoing a collaborative project with Professor Andrew K. Burroughs (Royal Free Hospital, London)

Alex Mowat 2010 Investigator’s Award

1st Prize (along with my PhD student, Dr Mytilinaiou) for the study entitled ‘Investigating the role of molecular mimicry and epitope spreading as mechanisms responsible for the development of antigen-specific immune responses in patients with autoimmune

D-P Bogdanos, CV

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hepatitis’.

EASL Sheila Sherlock Entry-level Fellowship Award 2010

Supervisor for the Award of Dr Maria Mytilinaiou ‘The role of the novel coinhibitory receptor B and T lymphocyte attenuator (BTLA) in the pathogenesis of concomitant autoimmune liver and rheumatological conditions’ (www.easl.eu).

EASL Sheila Sherlock Post-doc Fellowship Award 2008

Supervisor of Dr Athanasios Mavropoulos for the Award on ‘The role of p38 MAPK in the pathogenesis of autoimmune hepatitis’ (www.easl.eu). Dr Athanasios Mavropoulos is an immunobiologist and post-doc researcher.

EASL Sheila Sherlock Entry-level Fellowship Award 2005

Supervisor of Dr Francesca Meda: ‘B and T cell epitope mapping of the nuclear pore P62-Specific responses in patients with primary biliary cirrhosis’ (www.easl.eu).

November 2010 Presidential Distinction, AASLD 2010 (to Dr Maria Mytilinaiou & Dr Bogdanos)

April 2010 1st Prize, Alex Mowat Biennial Meeting (London) (to Dr Maria Mytilinaiou & Dr Bogdanos)

April 2007 Mentorship, Leventis Foundation (Paris) PhD Award (to support Dr Maria Mytilinaiou)

April 2008

Mentorship, Leventis Foundation (Paris) PhD Award (to support Dr Elias Spyrou)

Travel Bursary Awards for researchers in my group:

May 2011 Travel Burary Award, 44th ESPGHAN Annual Congress, Sorrento, Italy

April 2011 Travel Burary Award, 46th Liver International Congress, European Association for the Study of Liver (EASL), Berlin

April 2010 Travel Burary Award, 45th Liver International Congress, EASL, Vienna

April 2009 Travel Burary Award, 44th Liver International Congress, EASL, Copenhagen

April 2008 Travel Burary Award, 43rd Liver International Congress, EASL,

Milan

April 2007 Travel Burary Award, 42nd Liver International Congress, EASL, Barcelona

April 2006 Travel Burary Award, 41st Liver International Congress, EASL, Vienna

November 2004 Presidential Choice, 55th annual meeting, American Association for

D-P Bogdanos, CV

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the Study of Liver Diseases (AASLD), Boston

October 2004 Investigator’s Award, 142nd Falk Symposium, Freiburg, Germany

September 2004 Best Oral Presentation, BASL annual meeting, Cambridge, UK

July 2004 Awarded Poster, 2nd World Congress of Pediatric Gastroenterology, Hepatology and Nutrition (WCPGHAN), Paris, France

April 2004 Travel Burary Award, 43rd Liver International Congress, European Association for the Study of Liver (EASL), Milan

April 2004 Investigator’s Award, 5th Biennial Alex Mowat Meeting

April 2003 Best Poster Award, European Association for the Study of the

Liver (EASL), Geneva, Switzerland

October 2003 Investigator’s Award, 136th Falk Symposium, Freiburg, Germany

September 2000, 2001, 2003

BASL Travel Bursary Award

April 2001

Sir Bogue Visiting Research Fellowship Award, University of London (Host institution: Yale Medical School)

December 1999 Innovative Award (with Professor Vergani)-Multiple Sclerosis

Society of Great Britain

October 1999 President’s Choice, 50th AASLD annual meeting, Dallas, USA

May 1997 1st prize, 1st European Medical Students’ Symposium, Crete, Greece

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Editorial Activities:

1. Co-Editor-in-Chief: Innovation Immunology

2. Associate Editor: Autoimmunity Highlights, Archives of Medicine

(Laboratory Medicine, terminated 2014), Annals of Gastroenterologyb (Basic

Science), ImmunoGastroenterology (Immunology, terminated 2013),

Meditteranean J Rheumatology- Hellenic Rheumatology

3. Editorial Board Member: BMC Medicine, Autoimmunity Reviews, The

Scientific World Journal, World Journal of Rheumatology, BioMed Research

International, Open Datasets, Journal of Clinical Immunology and

Immunopathological Research, The Open Journal of Pathology; The Open

Journal of Rheumatology; Open Journal of Rheumatology and Autoimmune

Diseases

Regular or Ocasional Reviewer for the following journals (in alphabetical

order)

American Journal of Gastroenterology, Alimentary Pharmacology and Therapeutics,

Annals in Gastroenterology, Archives of Medical Science, Autoimmunity

Autoimmunity Reviews

Biomed Research International, BMC Gastroenterology, BMC Medicine,

Clinical Chemistry, Clinica Chimica Acta, Clinical and Developmental Immunology,

Clinical Experimental Immunology, Clinical Gastroenterology and Hepatology, Clinical

Infectious Diseases, Clinical Medicine Insights, Current Rheumatology Reviews,

Cytokine Research

Developmental and Comparative Immunology, Digestive and Liver Diseases, Dig Dis

Sciences

European J of Gastroenterology & Hepatology, Experimental Cell Research, , Expert

Reviews in Clinical Immunology, Expert Reviews in Gastroenterology and Hepatology

Gastroenterology, Gut

Hepatology

Immunology, ImmunoGastroenterology, Immunology Innovation, International

Journal of Immunopathology and Pharmacology

Journal of Autoimmune Diseases, Journal of Clinical Gastroenterology, Journal of

Clinical Immunology, Journal of Clinical Investigation, Journal of Clinical Pathology,

Journal of Hepatology, Journal of Immunology, Journal of Infectious Diseases

Liver International, Lupus

Medical Virology

Seminars in Liver Diseases, Steroids Biochemistry & Molecular Biology,

The Open Journal of Pathology, Toxins

D-P Bogdanos, CV

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ONGOING INTERNATIONAL COLLABORATIONS

USA: Professor M. Eric Gershwin (University of California at Davis, USA)

Professor Ditier Soll (Yale School of Medicine)

Canada: Professor Marvin Fritzler (University of Calgary)

Europe:

UK

Professor Diego Vergani (king’s College London)

Professor Giorgina Mieli-Vergani (King’s College London)

Professor Alastair Forbes (University College London & University of Norwich)

Germany:

Professor Ulrich Christen (University of Frankfurt);

Dr Jochen Mattner (Universität Erlangen-Nürnberg)

Professor Karsten Conrad (University of Dresden)

Professor Peter Schierack (University of Cottbus – Senftenberg)

Belgium: Professor Xavier Bossoyt (Univevrsity of

Italy: Prof Nicola Bizzaro (University of Venice);

Associate Professors Pietro Invernizzi & Carlo Selmi (University of Milan);

Associate Professors Marco Lenzi & Luigi Muratori (University of Bologna)

Spain: Professor Albert Pares (University of Barcelona)

Turkey: Dr Cumali Efe (University of Ankara)

Poland: Professor Piotr Milkiewicz (Pomeranian Medical University, Szczecin)

Russia: Dr Sergey V Lapin (St. Petersburg Pavlov State Medical University)

Australia: Professor Ian R. Mackay (Monash University)

GRANTS/FUNDING*

KRIPIS, General Secreteriat of Research & Technology, Hellenic Ministry of

Development & Research

HEFCE CLS award, Higher Education Funding Council for England’

E-rare Consortium: Epinostics ‘Autoimmune Liver Diseases: Epitope

peptide mapping’ EU FP7 grant

The Guy's & St Thomas' Charity Prize

Herakleitos GSRT, Hellenic Ministry of Development

Liver Immunodiagnostics 2736 –KCH Renal & Liver

D-P Bogdanos, CV

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EASL Post-doc Level Research Fellowship (2 fellowships)

EASL Entry Level Research Fellowship (3 fellowships)

EASL Visiting Research Fellowship (2 fellowship)

Leventis Foundation Fellowship

Liver Immunodiagnostics MJL9103 –Gene and Cell Based Therapy

King’s Charitable Trust

Alex Mowat Research Trust

Executive Academic Committee –ILS

Children’s Liver Disease Foundation

Fast Track UCL Research Committee

T.F.C Frost Charitable Trust

Multiple Sclerosis Society of Great Britain and Northern Ireland

Chronic Fatigue Syndrome Research Foundation

Action Research Foundation

PBC Foundation

Psoriasis Foundation

Funding support includes project, fellowship or award funding in isolation or combination with co-grant holders. The award from HEFCE totaling 500, 000 GBP was the highest amount of financial support given solely to Dimitrios P. Bogdanos for his research The total amount of the above mentioned financial support overexceeded 2,700,000 euros

Co-Organizer- Member of the Organising Committee of Congresses/Conferences/Meetings (2014-15)

1) Co-organizer of the 1st Israel-Greek International Meeting of Rheumatology and Autoimmunity, Haifa, Israel, 15 October 2015

2) Member of the Organising Committee of the 12th Dresden Symposium on Autoantibodies, Dresden, September 2015

3) Member of the Scientific Committee, EASL Monothematic Conference: Primary Biliary Cirrhosis (PBC), Milan, Italy, 23 & 24 May 2014

4) Member of the International Advisory Committee of the 9t Autoimmunity Congress 2014, Nice, France, March 2014

5) Member of the Organising Committee of the 11th Dresden Symposium, Dresden, Germany, September 2013

6) Member of the International Scientific Committee of the 8th Senftenberg Innovation Forum on Multiparametric Analysis: Autoimmunity Diagnostics, Senftenberg, Germany

Lectures in International meetings (Academic Year 2013-2015)

I am regular lecturer/speaker in International Conferences & Congresses 11th Dresden Symposium on Autoantibodies 1-4 September 2013

D-P Bogdanos, CV

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Title of Lecture: Possible role of infections in the pathogenesis of autoimmune liver diseases 11th Dresden Symposium on Autoantibodies 1-4 September 2013

Title of Lecture: GP2– The link between innate and acquired immune system in the intestine 25th Congress of the International Academy of Pathology - Arab Division. Amman, Jordan 7-9 November 2013 Title of Lecture: Autoimmunity in Inflammatory Bowel Diseases 25th Congress of the International Academy of Pathology - Arab Division. Amman, Jordan 7-9 November 2013 ̎Title of Lecture: Autoimmune Pancreatitis

25th Congress of the International Academy of Pathology - Arab Division. Amman, Jordan 7-9 November 2013 Title of Lecture: Risk Factors of Autoimmunity

8th Autoimmunity Congress, Nice, France 26-30 March, 2014 Title of Lecture: Infectome 8th Senftenberg Innovation Forum on Multiparametric Analysis: Autoimmunity Diagnostics, Senftenberg, Germany 7 & 8 May 2014

Title of Lecture: The desire to study the autoinfectome: a multiparametric approach EASL Monothematic Conference: Primary Biliary Cirrhosis (PBC) 23 & 24 May 2014 Title of Lecture: The role of B cells in Primary Biliary Cirrhosis 47th Annual meeting ESPGHAN 9-12 June 2014 Title of Lecture: Immunopathogenetic links between IBD and autoimmune liver disease

12th Dresden Symposium on Autoantibodies 23-26 September 2015 Title of lecture: Autoantibodies in liver autoimmunity: diagnostic clinical and prognostic significance

12th Dresden Symposium on Autoantibodies 23-25 September 2015 Title of lecture: Autoinfectome: a tool to study the link between infection and autoimmunity 1st Israel-Greek meeting of Rheumatology and Autoimmune diseases 15 October 2015 Title of lecture: the role of molecular mimicry in autoimmune liver diseases

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LIST OF PUBLICATIONS

Total: 181

Deposited in Pubmed: 157

Additional (non-deposited in Pubmed): 24

Papers Deposited in Pubmed http://www.ncbi.nlm.nih.gov/pubmed/?term=Bogdanos

1: Sakkas LI, Bogdanos DP. Systemic sclerosis: new evidence re-enforces the role of B cells. Autoimmun Rev. 2015 Oct 20. pii: S1568-9972(15)00217-7. doi: 10.1016/j.autrev.2015.10.005. [Epub ahead of print] PubMed PMID: 26497107. Review article 2: Mavropoulos A, Simopoulou T, Varna A, Liaskos C, Katsiari C, Bogdanos DP, Sakkas LI. B regulatory cells are decreased and functionally impaired in patients with systemic sclerosis. Arthritis Rheumatol. 2015 Sep 28. doi: 10.1002/art.39437. [Epub ahead of print] PubMed PMID: 26414243. Original article 3: Pavlidis P, Komorowski L, Teegen B, Liaskos C, Koutsoumpas AL, Smyk DS, Perricone C, Mytilinaiou MG, Stocker W, Forbes A, Bogdanos DP. Diagnostic and clinical significance of Crohn's disease-specific pancreatic anti-GP2 and anti-CUZD1 antibodies. Clin Chem Lab Med. 2015 Jul 18. doi:

10.1515/cclm-2015-0376. [Epub ahead of print] PubMed PMID: 26351932. Original article 4: Villalta D, Mytilinaiou MG, Elsner M, Hentschel C, Cuccato J, Somma V, Schierack P, Roggenbuck D, Bogdanos DP. Autoantibodies to asialoglycoprotein receptor (ASGPR) in patients with autoimmune liver diseases. Clin Chim Acta. 2015 Oct 23;450:1-5. doi: 10.1016/j.cca.2015.07.021. Epub 2015 Jul 26. PubMed PMID: 26220739. Original article 5: Norman GL, Gatselis NK, Shums Z, Liaskos C, Bogdanos DP, Koukoulis GK, Dalekos GN. Cartilage oligomeric matrix protein: A novel non-invasive marker for assessing cirrhosis and risk of hepatocellular carcinoma. World J Hepatol. 2015 Jul 18;7(14):1875-83. doi: 10.4254/wjh.v7.i14.1875. Original 6: Efe C, Bogdanos DP. Reply: To PMID 25002309. Dig Dis Sci. 2015 Apr;60(4):1107-8. PubMed PMID: 26086058. Letter

7: Scholz J, Grossmann K, Knütter I, Hiemann R, Sowa M, Röber N, Rödiger S, Schierack P, Reinhold D, Bogdanos DP, Meroni PL, Radice A, Conrad K, Roggenbuck D. Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing. Clin Chem Lab Med. 2015 May 15. pii: /j/cclm.ahead-of-print/cclm-2015-0083/cclm-2015-0083.xml. doi: 10.1515/cclm-2015-0083. [Epub ahead of print] PubMed PMID: 26020561. Original 8: Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D. Correction: Simultaneous Automated Screening and Confirmatory Testing for

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Vasculitis-Specific ANCA. PLoS One. 2015 May 13;10(5):e0127933. doi: 10.1371/journal.pone.0127933. eCollection 2015. PubMed PMID: 25970179; PubMed Central PMCID: PMC4430479. Not listed in the total number of papers 9: Bogdanos DP, Smyk DS, Rigopoulou EI, Sakkas LI, Shoenfeld Y. Infectomics and autoinfectomics: a tool to study infectious-induced autoimmunity. Lupus. 2015 Apr;24(4-5):364-73. doi: 10.1177/0961203314559088. PubMed PMID: 25801879. 10: Gkretsi V, Bogdanos DP. Experimental evidence of Migfilin as a new therapeutic target of hepatocellular carcinoma metastasis. Exp Cell Res. 2015 Jun 10;334(2):219-27. doi: 10.1016/j.yexcr.2015.03.002. Epub 2015 Mar 12. PubMed PMID: 25773778. 11: Gkretsi V, Bogdanos DP. Elimination of Ras Suppressor-1 from hepatocellular carcinoma cells hinders their in vitro metastatic properties. Anticancer Res. 2015 Mar;35(3):1509-12. PubMed PMID: 25750304.

12: Sakkas LI, Simopoulou T, Katsiari C, Bogdanos DP, Chikanza IC. Early systemic sclerosis-opportunities for treatment. Clin Rheumatol. 2015 Aug;34(8):1327-31. doi: 10.1007/s10067-015-2902-5. Epub 2015 Feb 26. PubMed PMID: 25711876. 13: Roggenbuck D, Röber N, Bogdanos DP, Goihl A, Reinhold D, Conrad K, Laass MW. Autoreactivity to isoforms of glycoprotein 2 in inflammatory bowel disease. Clin Chim Acta. 2015 Mar 10;442:82-3. doi: 10.1016/j.cca.2015.01.018. Epub 2015 Jan 24. PubMed PMID: 25625482. 14: Koutsoumpas AL, Smyk DS, Bogdanos DP. E. coli Induced Experimental Model of Primary Biliary Cirrhosis: At Last. Int J Hepatol. 2014;2014:848373. doi: 10.1155/2014/848373. Epub 2014 Dec 16. Review. PubMed PMID: 25580301; PubMed Central PMCID: PMC4280654. 15: Liaskos C, Spyrou V, Athanasiou LV, Orfanidou T, Mavropoulos A, Rigopoulou

EI, Amiridis GS, Shoenfeld Y, Billinis C, Bogdanos DP. Crohn's disease-specific anti-CUZD1 pancreatic antibodies are absent in ruminants with paratuberculosis. Clin Res Hepatol Gastroenterol. 2015 Jun;39(3):384-90. doi: 10.1016/j.clinre.2014.12.001. Epub 2015 Jan 6. PubMed PMID: 25575461. 16: Cantarini L, Rigante D, Vitale A, Napodano S, Sakkas LI, Bogdanos DP, Shoenfeld Y. Intravenous immunoglobulins (IVIG) in systemic sclerosis: a challenging yet promising future. Immunol Res. 2015 Mar;61(3):326-37. doi: 10.1007/s12026-014-8615-z. PubMed PMID: 25550086. 17: Pavlidis P, Shums Z, Koutsoumpas AL, Milo J, Papp M, Umemura T, Lakatos PL, Smyk DS, Bogdanos DP, Forbes A, Norman GL. Diagnostic and clinical significance of Crohn's disease-specific anti-MZGP2 pancreatic antibodies by a novel ELISA. Clin Chim Acta. 2015 Feb 20;441:176-81. doi: 10.1016/j.cca.2014.12.010. Epub 2014 Dec 12. PubMed PMID: 25512163.

18: Roggenbuck D, Vermeire S, Hoffman I, Reinhold D, Schierack P, Goihl A, von Arnim U, De Hertogh G, Polymeros D, Bogdanos DP, Bossuyt X. Evidence of Crohn's disease-related anti-glycoprotein 2 antibodies in patients with celiac disease. Clin Chem Lab Med. 2015 Aug 1;53(9):1349-57. doi: 10.1515/cclm-2014-0238. PubMed PMID: 25411995. 19: Raszeja-Wyszomirska J, Wunsch E, Krawczyk M, Rigopoulou EI, Bogdanos DP, Milkiewicz P. Prospective evaluation of PBC-specific health-related quality of life questionnaires in patients with primary sclerosing cholangitis. Liver Int. 2015 Jun;35(6):1764-71. doi: 10.1111/liv.12730. Epub 2014 Dec 4. PubMed PMID: 25388280.

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20: Sowa M, Grossmann K, Knütter I, Hiemann R, Röber N, Anderer U, Csernok E, Bogdanos DP, Borghi MO, Meroni PL, Schierack P, Reinhold D, Conrad K, Roggenbuck D. Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA. PLoS One. 2014 Sep 16;9(9):e107743. doi: 10.1371/journal.pone.0107743. eCollection 2014 21: Sakkas LI, Bogdanos DP, Katsiari C, Platsoucas CD. Anti-citrullinated peptides as autoantigens in rheumatoid arthritis-relevance to treatment. Autoimmun Rev. 2014 Nov;13(11):1114-20. doi: 10.1016/j.autrev.2014.08.012. Epub 2014 Aug 23. Review. PubMed PMID: 25182207. 22: Polymeros D, Tsiamoulos ZP, Koutsoumpas AL, Smyk DS, Mytilinaiou MG, Triantafyllou K, Bogdanos DP, Ladas SD. Bioinformatic and immunological analysis reveals lack of support for measles virus related mimicry in Crohn's disease. BMC Med. 2014 Aug 28;12:139. doi: 10.1186/s12916-014-0139-9. PubMed PMID: 25168804;

PubMed Central PMCID: PMC4171545. 23: Zachou K, Gampeta S, Gatselis NK, Oikonomou K, Goulis J, Manoussakis MN, Renaudineau Y, Bogdanos DP, Dalekos GN. Anti-SLA/LP alone or in combination with anti-Ro52 and fine specificity of anti-Ro52 antibodies in patients with autoimmune hepatitis. Liver Int. 2015 Feb;35(2):660-72. doi: 10.1111/liv.12658. Epub 2014 Aug 27. PubMed PMID: 25113420. 24: Efe C, Kav T, Aydin C, Cengiz M, Imga NN, Purnak T, Smyk DS, Torgutalp M, Turhan T, Ozenirler S, Ozaslan E, Bogdanos DP. Low serum vitamin D levels are associated with severe histological features and poor response to therapy in patients with autoimmune hepatitis. Dig Dis Sci. 2014 Dec;59(12):3035-42. doi: 10.1007/s10620-014-3267-3. Epub 2014 Jul 8. PubMed PMID: 25002309. 25: Maslyanskiy A, Lazareva N, Olinek P, Schierack P, Hentschel C, Cuccato J, Bogdanos DP, Lapin SV, Roggenbuck D. Anti-hnRNP B1 (RA33) autoantibodies are

associated with the clinical phenotype in Russian patients with rheumatoid arthritis and systemic sclerosis. J Immunol Res. 2014;2014:516593. doi: 10.1155/2014/516593. Epub 2014 May 4. PubMed PMID: 24883333; PubMed Central PMCID: PMC4027001. 26: Milkiewicz M, Kopycińska J, Kempińska-Podhorodecka A, Haas T, Bogdanos DP, Elias E, Milkiewicz P. Ursodeoxycholic acid influences the expression of p27kip1 but not FoxO1 in patients with non-cirrhotic primary biliary cirrhosis. J Immunol Res. 2014;2014:921285. doi: 10.1155/2014/921285. Epub 2014 Feb 5. PubMed PMID: 24741631; PubMed Central PMCID: PMC3987973. 27: Kotarska K, Wunsch E, Kempińska-Podhorodecka A, Raszeja-Wyszomirska J, Bogdanos DP, Wójcicki M, Milkiewicz P. Factors affecting health-related quality of life and physical activity after liver transplantation for autoimmune and nonautoimmune liver diseases: a prospective, single centre study. J Immunol Res. 2014;2014:738297. doi: 10.1155/2014/738297. Epub 2014 Mar 4. PubMed PMID:

24741621; PubMed Central PMCID: PMC3987938. 28: Mavropoulos A, Bogdanos DP, Liaskos C, Orfanidou T, Simopoulou T, Zafiriou E, Sakkas LI, Rigopoulou EI. Flow cytometric detection of p38 MAPK phosphorylation and intracellular cytokine expression in peripheral blood subpopulations from patients with autoimmune rheumatic diseases. J Immunol Res. 2014;2014:671431. doi: 10.1155/2014/671431. Epub 2014 Feb 3. PubMed PMID: 24741615; PubMed Central PMCID: PMC3987974. 29: Smyk DS, Koutsoumpas AL, Mytilinaiou MG, Rigopoulou EI, Sakkas LI, Bogdanos DP. Helicobacter pylori and autoimmune disease: cause or bystander. World J

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Gastroenterol. 2014 Jan 21;20(3):613-29. doi: 10.3748/wjg.v20.i3.613. Review. PubMed PMID: 24574735; PubMed Central PMCID: PMC3921471. 30: Rigopoulou EI, Bogdanos DP. Is primary biliary cirrhosis rare or common? The truth lies somewhere in between. Liver Int. 2014 Aug;34(7):e165-7. doi: 10.1111/liv.12488. PubMed PMID: 24517310. 31: Bogdanos DP, Smyk D, Shoenfeld Y. The microbiome of the lung. Isr Med Assoc J. 2013 Dec;15(12):766-7. PubMed PMID: 24449982. 32: Roggenbuck D, Reinhold D, Schierack P, Bogdanos DP, Conrad K, Laass MW. Crohn's disease specific pancreatic antibodies: clinical and pathophysiological challenges. Clin Chem Lab Med. 2014 Apr;52(4):483-94. doi: 10.1515/cclm-2013-0801. Review. PubMed PMID: 24231127. 33: Smyk DS, Mytilinaiou MG, Grammatikopoulos T, Knisely AS, Mieli-Vergani G,

Bogdanos DP, Vergani D. Primary biliary cirrhosis-specific antimitochondrial antibodies in neonatal haemochromatosis. Clin Dev Immunol. 2013;2013:642643. doi: 10.1155/2013/642643. Epub 2013 Sep 19. PubMed PMID: 24171034; PubMed Central PMCID: PMC3792542. 34: Mavropoulos A, Rigopoulou EI, Liaskos C, Bogdanos DP, Sakkas LI. The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis. Clin Dev Immunol. 2013;2013:569751. doi: 10.1155/2013/569751. Epub 2013 Sep 12. Review. PubMed PMID: 24151518; PubMed Central PMCID: PMC3787653. 35: Iacovakis C, Mamuris Z, Moutou KA, Touloudi A, Hammer AS, Valiakos G, Giannoulis T, Stamatis C, Spyrou V, Athanasiou LV, Kantere M, Asferg T, Giannakopoulos A, Salomonsen CM, Bogdanos DP, Birtsas P, Petrovska L, Hannant D, Billinis C. Polarisation of major histocompatibility complex II host genotype with pathogenesis of European Brown Hare syndrome virus. PLoS One. 2013 Sep 19;8(9):e74360. doi: 10.1371/journal.pone.0074360. eCollection 2013. PubMed PMID:

24069299; PubMed Central PMCID: PMC3778001. 36: Mavropoulos A, Orfanidou T, Liaskos C, Smyk DS, Spyrou V, Sakkas LI, Rigopoulou EI, Bogdanos DP. p38 MAPK Signaling in Pemphigus: Implications for Skin Autoimmunity. Autoimmune Dis. 2013;2013:728529. doi: 10.1155/2013/728529. Epub 2013 Jul 10. PubMed PMID: 23936634; PubMed Central PMCID: PMC3722958. 37: Liberal R, Grant CR, Sakkas L, Bizzaro N, Bogdanos DP. Diagnostic and clinical significance of anti-centromere antibodies in primary biliary cirrhosis. Clin Res Hepatol Gastroenterol. 2013 Dec;37(6):572-85. doi: 10.1016/j.clinre.2013.04.005. Epub 2013 Jul 19. PubMed PMID: 23876351. 38: Smyk DS, Orfanidou T, Invernizzi P, Bogdanos DP, Lenzi M. Vitamin D in autoimmune liver disease. Clin Res Hepatol Gastroenterol. 2013 Nov;37(5):535-45. doi: 10.1016/j.clinre.2013.05.016. Epub 2013 Jul 8. Review. PubMed PMID: 23845396.

39: Pavlidis P, Forbes A, Bogdanos DP. Anti-GP2 antibodies in inflammatory bowel disease patients with ileal pouch. J Crohns Colitis. 2013 Dec;7(11):e602-3. doi: 10.1016/j.crohns.2013.06.010. Epub 2013 Jul 9. PubMed PMID: 23845232. 40: Mahler M, Bogdanos DP, Pavlidis P, Fritzler MJ, Csernok E, Damoiseaux J, Bentow C, Shums Z, Forbes A, Norman GL. PR3-ANCA: a promising biomarker for ulcerative colitis with extensive disease. Clin Chim Acta. 2013 Sep 23;424:267-73. doi: 10.1016/j.cca.2013.06.005. Epub 2013 Jun 24. PubMed PMID: 23806819.

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41: Somma V, Ababneh H, Ababneh A, Gatti S, Romagnoli V, Bendia E, Conrad K, Bogdanos DP, Roggenbuck D, Ciarrocchi G. The Novel Crohn's Disease Marker Anti-GP2 Antibody Is Associated with Ileocolonic Location of Disease. Gastroenterol Res Pract. 2013;2013:683824. doi: 10.1155/2013/683824. Epub 2013 May 15. PubMed PMID: 23762038; PubMed Central PMCID: PMC3671301. 42: Roggenbuck D, Reinhold D, Werner L, Schierack P, Bogdanos DP, Conrad K. Glycoprotein 2 antibodies in Crohn's disease. Adv Clin Chem. 2013;60:187-208. Review. PubMed PMID: 23724745. 43: Bogdanos DP, Gao B, Gershwin ME. Liver immunology. Compr Physiol. 2013 Apr;3(2):567-98. doi: 10.1002/cphy.c120011. Review. PubMed PMID: 23720323; PubMed Central PMCID: PMC4201126. 44: Liaskos C, Rigopoulou EI, Orfanidou T, Bogdanos DP, Papandreou CN. CUZD1 and anti-CUZD1 antibodies as markers of cancer and inflammatory bowel diseases. Clin

Dev Immunol. 2013;2013:968041. doi: 10.1155/2013/968041. Epub 2013 Apr 22. Review. PubMed PMID: 23710207; PubMed Central PMCID: PMC3654630. 45: Raszeja-Wyszomirska J, Wunsch E, Kempinska-Podhorodecka A, Smyk DS, Bogdanos DP, Milkiewicz M, Milkiewicz P. TRAF1-C5 affects quality of life in patients with primary biliary cirrhosis. Clin Dev Immunol. 2013;2013:510547. doi: 10.1155/2013/510547. Epub 2013 Apr 28. PubMed PMID: 23710202; PubMed Central PMCID: PMC3655458. 46: Liaskos C, Spyrou V, Roggenbuck D, Athanasiou LV, Orfanidou T, Mavropoulos A, Reinhold D, Rigopoulou EI, Amiridis GS, Billinis C, Bogdanos DP. Crohn's disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: implications for the pathogenesis of the human disease. Autoimmunity. 2013 Sep;46(6):388-94. doi: 10.3109/08916934.2013.786047. Epub 2013 May 2. PubMed PMID: 23638886.

47: Kundzer AV, Volkova MV, Bogdanos DP, Rödiger S, Schierack P, Generalov I, Nevinsky GA, Roggenbuck D. Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides. Immunol Res. 2013 Jul;56(2-3):457-64. doi: 10.1007/s12026-013-8424-9. PubMed PMID: 23592052. 48: Bogdanos DP, Smyk DS, Invernizzi P, Rigopoulou EI, Blank M, Sakkas L, Pouria S, Shoenfeld Y. Tracing environmental markers of autoimmunity: introducing the infectome. Immunol Res. 2013 Jul;56(2-3):220-40. doi: 10.1007/s12026-013-8399-6. Review. PubMed PMID: 23592050. 49: Invernizzi P, Bossuyt X, Bogdanos DP. Serum autoantibodies: from identification to clinical relevance. Clin Dev Immunol. 2013;2013:382069. doi: 10.1155/2013/382069. Epub 2013 Mar 20. PubMed PMID: 23573110; PubMed Central PMCID: PMC3615582. 50: Smyk D, Rigopoulou EI, Bizzaro N, Bogdanos DP. Hair dyes as a risk for

autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis. Auto Immun Highlights. 2012 Jan 13;4(1):1-9. doi: 10.1007/s13317-011-0027-7. eCollection 2013 Apr. PubMed PMID: 26000137; PubMed Central PMCID: PMC4389085. 51: Roggenbuck D, Hiemann R, Bogdanos DP, Reinhold D, Conrad K. Standardization of automated interpretation of immunofluorescence tests. Clin Chim Acta. 2013 Jun 5;421:168-9. doi: 10.1016/j.cca.2013.03.019. Epub 2013 Mar 26. PubMed PMID: 23537734. 52: Radzimski C, Probst C, Teegen B, Rentzsch K, Blöcker IM, Dähnrich C, Schlumberger W, Stöcker W, Bogdanos DP, Komorowski L. Development of a

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recombinant cell-based indirect immunofluorescence assay for the determination of autoantibodies against soluble liver antigen in autoimmune hepatitis. Clin Dev Immunol. 2013;2013:572815. doi: 10.1155/2013/572815. Epub 2013 Jan 16. PubMed PMID: 23401700; PubMed Central PMCID: PMC3562650. 53: Roggenbuck D, Bogdanos DP, Conrad K. Loss of tolerance to one or two major targets in Crohn's disease or just cross-reactivity? J Crohns Colitis. 2013 Aug;7(7):e273-4. doi: 10.1016/j.crohns.2012.12.013. Epub 2013 Jan 20. PubMed PMID: 23337370. 54: Probst C, Radzimski C, Blöcker IM, Teegen B, Bogdanos DP, Stöcker W, Komorowski L. Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against "rings and rods"-associated inosine-5'-monophosphate dehydrogenase 2 in viral hepatitis C. Clin Chim Acta. 2013 Mar 15;418:91-6. doi: 10.1016/j.cca.2013.01.003. Epub 2013 Jan 16. PubMed PMID: 23333419.

55: Willitzki A, Hiemann R, Peters V, Sack U, Schierack P, Rödiger S, Anderer U, Conrad K, Bogdanos DP, Reinhold D, Roggenbuck D. New platform technology for comprehensive serological diagnostics of autoimmune diseases. Clin Dev Immunol. 2012;2012:284740. doi: 10.1155/2012/284740. Epub 2012 Dec 19. Review. PubMed PMID: 23316252; PubMed Central PMCID: PMC3536031. 56: Bogdanos DP, Smyk DS, Invernizzi P, Rigopoulou EI, Blank M, Pouria S, Shoenfeld Y. Infectome: a platform to trace infectious triggers of autoimmunity. Autoimmun Rev. 2013 May;12(7):726-40. doi: 10.1016/j.autrev.2012.12.005. Epub 2012 Dec 22. Review. PubMed PMID: 23266520. 57: Smyk DS, Bogdanos DP, Pares A, Liaskos C, Billinis C, Burroughs AK, Rigopoulou EI. Tuberculosis is not a risk factor for primary biliary cirrhosis: a review of the literature. Tuberc Res Treat. 2012;2012:218183. doi: 10.1155/2012/218183. Epub 2012 Oct 30. PubMed PMID: 23213506; PubMed Central

PMCID: PMC3504403. 58: Mavropoulos A, Orfanidou T, Liaskos C, Smyk DS, Billinis C, Blank M, Rigopoulou EI, Bogdanos DP. p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: lessons to learn from ANCA vasculitis and pemphigus vulgaris. Autoimmun Rev. 2013 Mar;12(5):580-90. doi: 10.1016/j.autrev.2012.10.019. Epub 2012 Nov 30. Review. PubMed PMID: 23207287. 59: Ehser J, Holdener M, Christen S, Bayer M, Pfeilschifter JM, Hintermann E, Bogdanos DP, Christen U. Molecular mimicry rather than identity breaks T-cell tolerance in the CYP2D6 mouse model for human autoimmune hepatitis. J Autoimmun. 2013 May;42:39-49. doi: 10.1016/j.jaut.2012.11.001. Epub 2012 Nov 28. PubMed PMID: 23200317. 60: Smyk DS, Rigopoulou EI, Bogdanos DP. Potential Roles for Infectious Agents in the Pathophysiology of Primary Biliary Cirrhosis: What's New? Curr Infect Dis

Rep. 2013 Feb;15(1):14-24. doi: 10.1007/s11908-012-0304-2. PubMed PMID: 23188623. 61: Smyk DS, Bogdanos DP, Mytilinaiou MG, Burroughs AK, Rigopoulou EI. Rheumatoid arthritis and primary biliary cirrhosis: cause, consequence, or coincidence? Arthritis. 2012;2012:391567. doi: 10.1155/2012/391567. Epub 2012 Oct 24. PubMed PMID: 23150824; PubMed Central PMCID: PMC3488395. 62: Kempinska-Podhorodecka A, Shums Z, Wasilewicz M, Wunsch E, Milkiewicz M, Bogdanos DP, Norman GL, Milkiewicz P. TRAF1 gene polymorphism correlates with the titre of Gp210 antibody in patients with primary biliary cirrhosis. Clin Dev Immunol. 2012;2012:487521. doi: 10.1155/2012/487521. Epub 2012 Oct 22. PubMed

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PMID: 23125866; PubMed Central PMCID: PMC3485529. 63: Pavlidis P, Romanidou O, Roggenbuck D, Mytilinaiou MG, Al-Sulttan F, Liaskos C, Smyk DS, Koutsoumpas AL, Rigopoulou EI, Conrad K, Forbes A, Bogdanos DP. Ileal inflammation may trigger the development of GP2-specific pancreatic autoantibodies in patients with Crohn's disease. Clin Dev Immunol. 2012;2012:640835. doi: 10.1155/2012/640835. Epub 2012 Oct 17. PubMed PMID: 23118780; PubMed Central PMCID: PMC3483735. 64: Bogdanos DP, Gershwin ME. What is new in primary biliary cirrhosis? Dig Dis. 2012;30 Suppl 1:20-31. doi: 10.1159/000341118. Epub 2012 Oct 11. Review. PubMed PMID: 23075865. 65: Roggenbuck D, Humbel RL, Reinhold D, Bogdanos DP, Conrad K, Laass MW. Glycoprotein 2 antibodies in inflammatory bowel disease: no association with disease phenotype? J Pediatr Gastroenterol Nutr. 2013 Jan;56(1):e5. doi:

10.1097/MPG.0b013e318275fa77. PubMed PMID: 23059646. 66: Smyk D, Rigopoulou EI, Zen Y, Abeles RD, Billinis C, Pares A, Bogdanos DP. Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis? World J Gastroenterol. 2012 Sep 21;18(35):4855-65. Review. PubMed PMID: 23002357; PubMed Central PMCID: PMC3447267. 67: Smyk DS, Rigopoulou EI, Pares A, Mytilinaiou MG, Invernizzi P, Bogdanos DP. Familial primary biliary cirrhosis: like mother, like daughter? Acta Gastroenterol Belg. 2012 Jun;75(2):203-9. Review. PubMed PMID: 22870783. 68: Bogdanos DP, Roggenbuck D, Reinhold D, Wex T, Pavlidis P, von Arnim U, Malfertheiner P, Forbes A, Conrad K, Laass MW. Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease. BMC Gastroenterol. 2012 Aug 6;12:102. PubMed PMID: 22866900; PubMed Central PMCID: PMC3449192.

69: Smyk DS, Rigopoulou EI, Koutsoumpas AL, Kriese S, Burroughs AK, Bogdanos DP. Autoantibodies in autoimmune pancreatitis. Int J Rheumatol. 2012;2012:940831. doi: 10.1155/2012/940831. Epub 2012 Jul 12. PubMed PMID: 22844291; PubMed Central PMCID: PMC3403403. 70: Invernizzi P, Alessio MG, Smyk DS, Lleo A, Sonzogni A, Fabris L, Candusso M, Bogdanos DP, Iorio R, Torre G. Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and review of the literature. BMC Gastroenterol. 2012 Jul 20;12:92. doi: 10.1186/1471-230X-12-92. Review. PubMed PMID: 22816667; PubMed Central PMCID: PMC3464927. 71: Smyk DS, Rigopoulou EI, Pares A, Billinis C, Burroughs AK, Muratori L, Invernizzi P, Bogdanos DP. Sex differences associated with primary biliary cirrhosis. Clin Dev Immunol. 2012;2012:610504. doi: 10.1155/2012/610504. Epub

2012 May 30. Review. PubMed PMID: 22693524; PubMed Central PMCID: PMC3369468. 72: Rigopoulou EI, Smyk DS, Matthews CE, Billinis C, Burroughs AK, Lenzi M, Bogdanos DP. Epstein-barr virus as a trigger of autoimmune liver diseases. Adv Virol. 2012;2012:987471. doi: 10.1155/2012/987471. Epub 2012 May 28. PubMed PMID: 22693505; PubMed Central PMCID: PMC3368154. 73: Rigopoulou EI, Roggenbuck D, Smyk DS, Liaskos C, Mytilinaiou MG, Feist E, Conrad K, Bogdanos DP. Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: lost and found. Autoimmun Rev. 2012 Dec;12(2):260-9. doi: 10.1016/j.autrev.2012.04.005. Epub 2012 May 1. Review. PubMed PMID: 22571878.

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74: Mytilinaiou MG, Meyer W, Scheper T, Rigopoulou EI, Probst C, Koutsoumpas AL, Abeles D, Burroughs AK, Komorowski L, Vergani D, Bogdanos DP. Diagnostic and clinical utility of antibodies against the nuclear body promyelocytic leukaemia and Sp100 antigens in patients with primary biliary cirrhosis. Clin Chim Acta. 2012 Aug 16;413(15-16):1211-6. doi: 10.1016/j.cca.2012.03.020. Epub 2012 Apr 3. PubMed PMID: 22503841. 75: Duarte-Rey C, Bogdanos DP, Yang CY, Roberts K, Leung PS, Anaya JM, Worman HJ, Gershwin ME. Primary biliary cirrhosis and the nuclear pore complex. Autoimmun Rev. 2012 Oct;11(12):898-902. doi: 10.1016/j.autrev.2012.03.005. Epub 2012 Apr 1. Review. PubMed PMID: 22487189; PubMed Central PMCID: PMC3396748. 76: Smyk DS, Mytilinaiou MG, Milkiewicz P, Rigopoulou EI, Invernizzi P, Bogdanos DP. Towards systemic sclerosis and away from primary biliary cirrhosis: the case of PTPN22. Auto Immun Highlights. 2011 Sep 7;3(1):1-9. doi:

10.1007/s13317-011-0023-y. eCollection 2012 Apr. Review. PubMed PMID: 26000122; PubMed Central PMCID: PMC4389021. 77: Rigamonti C, Bogdanos DP, Mytilinaiou MG, Smyk DS, Rigopoulou EI, Burroughs AK. Primary biliary cirrhosis associated with systemic sclerosis: diagnostic and clinical challenges. Int J Rheumatol. 2011;2011:976427. doi: 10.1155/2011/976427. Epub 2011 Dec 6. PubMed PMID: 22187566; PubMed Central PMCID: PMC3236477. 78: Duarte-Rey C, Bogdanos DP, Leung PS, Anaya JM, Gershwin ME. IgM predominance in autoimmune disease: genetics and gender. Autoimmun Rev. 2012 May;11(6-7):A404-12. doi: 10.1016/j.autrev.2011.12.001. Epub 2011 Dec 8. Review. PubMed PMID: 22178509. 79: Bogdanos DP, Smyk DS, Rigopoulou EI, Mytilinaiou MG, Heneghan MA, Selmi C, Gershwin ME. Twin studies in autoimmune disease: genetics, gender and environment. J Autoimmun. 2012 May;38(2-3):J156-69. doi:

10.1016/j.jaut.2011.11.003. Epub 2011 Dec 15. Review. PubMed PMID: 22177232. 80: Smyk DS, Rigopoulou EI, Muratori L, Burroughs AK, Bogdanos DP. Smoking as a risk factor for autoimmune liver disease: what we can learn from primary biliary cirrhosis. Ann Hepatol. 2012 Jan-Feb;11(1):7-14. Review. PubMed PMID: 22166556. 81: Zen Y, Bogdanos DP, Kawa S. Type 1 autoimmune pancreatitis. Orphanet J Rare Dis. 2011 Dec 7;6:82. doi: 10.1186/1750-1172-6-82. Review. PubMed PMID: 22151922; PubMed Central PMCID: PMC3261813. 82: Smyk DS, Rigopoulou EI, Lleo A, Abeles RD, Mavropoulos A, Billinis C, Invernizzi P, Bogdanos DP. Immunopathogenesis of primary biliary cirrhosis: an old wives' tale. Immun Ageing. 2011 Dec 2;8(1):12. doi: 10.1186/1742-4933-8-12. PubMed PMID: 22136162; PubMed Central PMCID: PMC3238302. 83: Mavropoulos A, Smyk D, Rigopoulou EI, Bogdanos DP. Human peripheral blood

mononuclear cell culture for flow cytometric analysis of phosphorylated mitogen-activated protein kinases. Methods Mol Biol. 2012;806:275-85. doi: 10.1007/978-1-61779-367-7_19. PubMed PMID: 22057459. 84: Bogdanos DP, Rigopoulou EI, Smyk DS, Roggenbuck D, Reinhold D, Forbes A, Laass MW, Conrad K. Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies. Autoimmun Rev. 2011 Dec;11(2):143-8. doi: 10.1016/j.autrev.2011.09.004. Epub 2011 Sep 29. Review. PubMed PMID: 21983481. 85: Smyk DS, Bogdanos DP, Kriese S, Billinis C, Burroughs AK, Rigopoulou EI.

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Urinary tract infection as a risk factor for autoimmune liver disease: from bench to bedside. Clin Res Hepatol Gastroenterol. 2012 Apr;36(2):110-21. doi: 10.1016/j.clinre.2011.07.013. Epub 2011 Sep 8. Review. PubMed PMID: 21907008. 86: Smyk D, Cholongitas E, Kriese S, Rigopoulou EI, Bogdanos DP. Primary biliary cirrhosis: family stories. Autoimmune Dis. 2011;2011:189585. doi: 10.4061/2011/189585. Epub 2011 May 5. PubMed PMID: 21687641; PubMed Central PMCID: PMC3112499. 87: Smyk D, Grammatikopoulos T, Daponte A, Rigopoulou EI, Bogdanos DP. Fetomaternal alloimmunity as a cause of liver disease. Auto Immun Highlights. 2011 Mar 23;2(1):21-8. doi: 10.1007/s13317-011-0019-7. eCollection 2011 May. Review. PubMed PMID: 26000116; PubMed Central PMCID: PMC4389071. 88: Koutsoumpas A, Polymeros D, Tsiamoulos Z, Smyk D, Karamanolis G, Triantafyllou K, Rigopoulou EI, Forbes A, Vergani D, Bogdanos DP, Ladas SD.

Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease. J Crohns Colitis. 2011 Apr;5(2):101-9. doi: 10.1016/j.crohns.2010.10.009. Epub 2010 Dec 3. PubMed PMID: 21453878. 89: Smyk D, Rigopoulou EI, Baum H, Burroughs AK, Vergani D, Bogdanos DP. Autoimmunity and environment: am I at risk? Clin Rev Allergy Immunol. 2012 Apr;42(2):199-212. doi: 10.1007/s12016-011-8259-x. Review. PubMed PMID: 21337133. 90: Pavlidis P, Forbes A, Bogdanos DP. Antibodies to glycoprotein 2 (GP2) in patients with inflammatory bowel diseases from UK. Clin Chim Acta. 2011 May 12;412(11-12):1163-4. doi: 10.1016/j.cca.2011.02.005. Epub 2011 Feb 15. PubMed PMID: 21329686. 91: Smyk D, Mytilinaiou MG, Rigopoulou EI, Bogdanos DP. PBC triggers in water reservoirs, coal mining areas and waste disposal sites: from Newcastle to New York. Dis Markers. 2010;29(6):337-44. doi: 10.3233/DMA-2010-0744. Review. PubMed

PMID: 21297253; PubMed Central PMCID: PMC3835285. 92: Bogdanos DP, Baum H, Vergani D, Burroughs AK. The role of E. coli infection

in the pathogenesis of primary biliary cirrhosis. Dis Markers. 2010;29(6):301-11.

doi: 10.3233/DMA-2010-0745. Review. PubMed PMID: 21297249; PubMed Central PMCID:

PMC3835537.

93: Roggenbuck D, Reinhold D, Wex T, Goihl A, von Arnim U, Malfertheiner P, Büttner T, Porstmann T, Porstmann S, Liedvogel B, Bogdanos DP, Laass MW, Conrad K. Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease. Clin Chim Acta. 2011 Apr 11;412(9-10):718-24. doi: 10.1016/j.cca.2010.12.029. Epub 2010 Dec 31. PubMed PMID: 21195704. 94: Bogdanos DP, Komorowski L. Disease-specific autoantibodies in primary biliary cirrhosis. Clin Chim Acta. 2011 Mar 18;412(7-8):502-12. doi:

10.1016/j.cca.2010.12.019. Epub 2010 Dec 23. Review. PubMed PMID: 21185272. 95: Liu H, Norman GL, Shums Z, Worman HJ, Krawitt EL, Bizzaro N, Vergani D, Bogdanos DP, Dalekos GN, Milkiewicz P, Czaja AJ, Heathcote EJ, Hirschfield GM, Tan EM, Miyachi K, Bignotto M, Battezzati PM, Lleo A, Leung PS, Podda M, Gershwin ME, Invernizzi P. PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis. J Autoimmun. 2010 Dec;35(4):436-42. doi: 10.1016/j.jaut.2010.09.005. Epub 2010 Oct 6. PubMed PMID: 20932720. 96: Koutsoumpas A, Mytilinaiou M, Polymeros D, Dalekos GN, Bogdanos DP.

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Anti-Helicobacter pylori antibody responses specific for VacA do not trigger primary biliary cirrhosis-specific antimitochondrial antibodies. Eur J Gastroenterol Hepatol. 2009 Oct;21(10):1220. doi: 10.1097/MEG.0b013e32831a4807. PubMed PMID: 19749508. 97: Bogdanos DP, Mieli-Vergani G, Vergani D. Autoantibodies and their antigens in autoimmune hepatitis. Semin Liver Dis. 2009 Aug;29(3):241-53. doi: 10.1055/s-0029-1233533. Epub 2009 Aug 12. Review. PubMed PMID: 19675997. 98: Mytilinaiou MG, Bogdanos DP. Primary biliary cirrhosis-specific autoantibodies in patients with systemic sclerosis. Dig Liver Dis. 2009 Dec;41(12):916; author reply 916-7. doi: 10.1016/j.dld.2009.05.005. Epub 2009 Jul 14. PubMed PMID: 19604733. 99: Vergani D, Longhi MS, Bogdanos DP, Ma Y, Mieli-Vergani G. Autoimmune hepatitis. Semin Immunopathol. 2009 Sep;31(3):421-35. doi:

10.1007/s00281-009-0170-7. Epub 2009 Jun 17. Review. PubMed PMID: 19533129. 100: Dähnrich C, Pares A, Caballeria L, Rosemann A, Schlumberger W, Probst C, Mytilinaiou M, Bogdanos DP, Vergani D, Stöcker W, Komorowski L. New ELISA for detecting primary biliary cirrhosis-specific antimitochondrial antibodies. Clin Chem. 2009 May;55(5):978-85. doi: 10.1373/clinchem.2008.118299. Epub 2009 Mar 5. PubMed PMID: 19264849. 101: Bogdanos DP, Dalekos GN. Enzymes as target antigens of liver-specific autoimmunity: the case of cytochromes P450s. Curr Med Chem. 2008;15(22):2285-92. Review. PubMed PMID: 18781950. 102: Bogdanos DP, Pusl T, Rust C, Vergani D, Beuers U. Primary biliary cirrhosis following Lactobacillus vaccination for recurrent vaginitis. J Hepatol. 2008 Sep;49(3):466-73. doi: 10.1016/j.jhep.2008.05.022. Epub 2008 Jun 25. PubMed PMID: 18644655.

103: Bogdanos DP, Invernizzi P, Mackay IR, Vergani D. Autoimmune liver serology: current diagnostic and clinical challenges. World J Gastroenterol. 2008 Jun 7;14(21):3374-87. Review. PubMed PMID: 18528935; PubMed Central PMCID: PMC2716592. 104: Bogdanos DP, Vergani D. Bacteria and primary biliary cirrhosis. Clin Rev Allergy Immunol. 2009 Feb;36(1):30-9. doi: 10.1007/s12016-008-8087-9. Review. PubMed PMID: 18498061. 105: Granito A, Stanzani M, Muratori L, Bogdanos DP, Muratori P, Pappas G, Quarneti C, Lenzi M, Vergani D, Bianchi FB. LKM1-positive type 2 autoimmune hepatitis following allogenic hematopoietic stem-cell transplantation. Am J Gastroenterol. 2008 May;103(5):1313-4. doi: 10.1111/j.1572-0241.2007.01782_7.x. PubMed PMID: 18477361.

106: Dalekos GN, Bogdanos DP, Neuberger J. Celiac disease-related autoantibodies in end-stage autoimmune liver diseases: what is the message? Liver Int. 2008 Apr;28(4):426-8. doi: 10.1111/j.1478-3231.2008.01708.x. PubMed PMID: 18339068. 107: Bernal W, Meda F, Ma Y, Bogdanos DP, Vergani D. Disease-specific autoantibodies in patients with acute liver failure: the King's College London Experience. Hepatology. 2008 Mar;47(3):1096-7; author reply 1097. doi: 10.1002/hep.22179. PubMed PMID: 18306217. 108: Rigopoulou EI, Davies ET, Bogdanos DP, Liaskos C, Mytilinaiou M, Koukoulis GK, Dalekos GN, Vergani D. Antimitochondrial antibodies of immunoglobulin G3

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subclass are associated with a more severe disease course in primary biliary cirrhosis. Liver Int. 2007 Nov;27(9):1226-31. PubMed PMID: 17919234. 109: Longhi MS, Hussain MJ, Bogdanos DP, Quaglia A, Mieli-Vergani G, Ma Y, Vergani D. Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2. Hepatology. 2007 Aug;46(2):472-84. PubMed PMID: 17559153. 110: Bogdanos DP, Liaskos C, Pares A, Norman G, Rigopoulou EI, Caballeria L, Dalekos GN, Rodes J, Vergani D. Anti-gp210 antibody mirrors disease severity in primary biliary cirrhosis. Hepatology. 2007 Jun;45(6):1583; author reply 1583-4. PubMed PMID: 17538935. 111: Rigopoulou EI, Bogdanos DP, Liaskos C, Koutsoumpas A, Baum H, Vergani D, Dalekos GN. Anti-mitochondrial antibody immunofluorescent titres correlate with the number and intensity of immunoblot-detected mitochondrial bands in patients

with primary biliary cirrhosis. Clin Chim Acta. 2007 May 1;380(1-2):118-21. Epub 2007 Feb 1. PubMed PMID: 17321509. 112: Liaskos C, Bogdanos DP, Rigopoulou EI, Dalekos GN. Development of antimitochondrial antibodies in patients with autoimmune hepatitis: art of facts or an artifact? J Gastroenterol Hepatol. 2007 Mar;22(3):454-5. PubMed PMID: 17295788. 113: Rigopoulou EI, Dalekos G, Bogdanos DP. How common are connective tissue disorders in patients with autoimmune hepatitis? Semin Arthritis Rheum. 2007 Apr;36(5):332; author reply 333. Epub 2007 Feb 5. PubMed PMID: 17276497. 114: Liaskos C, Bogdanos DP, Davies ET, Dalekos GN. Diagnostic relevance of anti-filamentous actin antibodies in autoimmune hepatitis. J Clin Pathol. 2007 Jan;60(1):107-8. PubMed PMID: 17213359; PubMed Central PMCID: PMC1860582.

115: Bogdanos DP, Rigopoulou EI. Viral/self-mimicry and immunological cross-reactivity as a trigger of hepatic C virus associated autoimmune diabetes. Diabetes Res Clin Pract. 2007 Jul;77(1):155-6. Epub 2006 Nov 21. PubMed PMID: 17118481. 116: Mullighan CG, Bogdanos DP, Vergani D, Bardy PG. Cytochrome P450 1A2 is a target antigen in hepatitic graft-versus-host disease. Bone Marrow Transplant. 2006 Nov;38(10):703-5. Epub 2006 Sep 25. PubMed PMID: 17001344. 117: Bogdanos DP, Koutsoumpas A, Baum H, Vergani D. Borrelia Burgdorferi: a new self-mimicking trigger in primary biliary cirrhosis. Dig Liver Dis. 2006 Oct;38(10):781-2; author reply 782-3. Epub 2006 Jul 25. PubMed PMID: 16870516. 118: Bogdanos DP, Vergani D. Origin of cross-reactive autoimmunity in primary biliary cirrhosis. Liver Int. 2006 Aug;26(6):633-5. Review. PubMed PMID: 16842317.

119: Polymeros D, Bogdanos DP, Day R, Arioli D, Vergani D, Forbes A. Does cross-reactivity between mycobacterium avium paratuberculosis and human intestinal antigens characterize Crohn's disease? Gastroenterology. 2006 Jul;131(1):85-96. PubMed PMID: 16831593. 120: Bogdanos DP, Rigopoulou EI. Self-mimicking autoimmune domains of hepatitis C virus core antigen. Vaccine. 2006 Sep 11;24(37-39):6173-4. Epub 2006 Jun 9. PubMed PMID: 16806599. 121: Bogdanos DP, Liaskos C, Rigopoulou EI, Dalekos GN. Anti-mitochondrial

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antibodies in patients with systemic lupus erythematosus: revealing the unforeseen. Clin Chim Acta. 2006 Nov;373(1-2):183-4; author reply 185. Epub 2006 Apr 7. PubMed PMID: 16714006. 122: Ma Y, Bogdanos DP, Hussain MJ, Underhill J, Bansal S, Longhi MS, Cheeseman P, Mieli-Vergani G, Vergani D. Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2. Gastroenterology. 2006 Mar;130(3):868-82. PubMed PMID: 16530525. 123: Bogdanos DP, Smith H, Ma Y, Baum H, Mieli-Vergani G, Vergani D. A study of molecular mimicry and immunological cross-reactivity between hepatitis B surface antigen and myelin mimics. Clin Dev Immunol. 2005 Sep;12(3):217-24. PubMed PMID: 16295528; PubMed Central PMCID: PMC2275415. 124: Bogdanos DP, Baum H, Okamoto M, Montalto P, Sharma UC, Rigopoulou EI, Vlachogiannakos J, Ma Y, Burroughs AK, Vergani D. Primary biliary cirrhosis is

characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic. Hepatology. 2005 Aug;42(2):458-65. PubMed PMID: 16025495. 125: Longhi MS, Ma Y, Mitry RR, Bogdanos DP, Heneghan M, Cheeseman P, Mieli-Vergani G, Vergani D. Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis. J Autoimmun. 2005 Aug;25(1):63-71. PubMed PMID: 16005184. 126: Muratori L, Bogdanos DP, Muratori P, Lenzi M, Granito A, Ma Y, Mieli-Vergani G, Bianchi FB, Vergani D. Susceptibility to thyroid disorders in hepatitis C. Clin Gastroenterol Hepatol. 2005 Jun;3(6):595-603. PubMed PMID: 15952102. 127: Rigopoulou EI, Davies ET, Pares A, Zachou K, Liaskos C, Bogdanos DP, Rodes J, Dalekos GN, Vergani D. Prevalence and clinical significance of isotype specific antinuclear antibodies in primary biliary cirrhosis. Gut. 2005

Apr;54(4):528-32. PubMed PMID: 15753539; PubMed Central PMCID: PMC1774444. 128: Bogdanos DP, Mieli-Vergani G, Vergani D. Non-organ-specific autoantibodies in hepatitis C virus infection: do they matter? Clin Infect Dis. 2005 Feb 15;40(4):508-10. Epub 2005 Jan 21. PubMed PMID: 15712071. 129: Ma Y, Meregalli M, Hodges S, Davies N, Bogdanos DP, Fargion S, Fiorelli G, Vergani D. Alcohol dehydrogenase: an autoantibody target in patients with alcoholic liver disease. Int J Immunopathol Pharmacol. 2005 Jan-Mar;18(1):173-82. PubMed PMID: 15698522. 130: Bogdanos DP, Gilbert D, Bianchi I, Leoni S, Mitry RR, Ma Y, Mieli-Vergani G, Vergani D. Antibodies to soluble liver antigen and alpha-enolase in patients with autoimmune hepatitis. J Autoimmune Dis. 2004 Nov 19;1(1):4. PubMed PMID: 15679947; PubMed Central PMCID: PMC546408.

131: Bogdanos DP, Baum H, Gunsar F, Arioli D, Polymeros D, Ma Y, Burroughs AK, Vergani D. Extensive homology between the major immunodominant mitochondrial antigen in primary biliary cirrhosis and Helicobacter pylori does not lead to immunological cross-reactivity. Scand J Gastroenterol. 2004 Oct;39(10):981-7. PubMed PMID: 15513338. 132: Longhi MS, Ma Y, Bogdanos DP, Cheeseman P, Mieli-Vergani G, Vergani D. Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease. J Hepatol. 2004 Jul;41(1):31-7. PubMed PMID: 15246204. 133: Bogdanos DP, Mieli-Vergani G, Vergani D. Non-organ-specific autoantibodies

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in children with chronic hepatitis C virus infection. Clin Infect Dis. 2004 May 15;38(10):1505; author reply 1505-6. PubMed PMID: 15156495. 134: Bogdanos DP, Vergani D, Muratori P, Muratori L, Bianchi FB. Specificity of anti-sp100 antibody for primary biliary cirrhosis. Scand J Gastroenterol. 2004 Apr;39(4):405-6; author reply 407. PubMed PMID: 15125479. 135: Bogdanos DP, Pares A, Baum H, Caballeria L, Rigopoulou EI, Ma Y, Burroughs AK, Rodes J, Vergani D. Disease-specific cross-reactivity between mimicking peptides of heat shock protein of Mycobacterium gordonae and dominant epitope of E2 subunit of pyruvate dehydrogenase is common in Spanish but not British patients with primary biliary cirrhosis. J Autoimmun. 2004 Jun;22(4):353-62. PubMed PMID: 15120760. 136: Bogdanos DP, Pares A, Rodés J, Vergani D. Primary biliary cirrhosis specific antinuclear antibodies in patients from Spain. Am J Gastroenterol. 2004

Apr;99(4):763-4; author reply 765. PubMed PMID: 15089915. 137: Bogdanos DP, Lenzi M, Okamoto M, Rigopoulou EI, Muratori P, Ma Y, Muratori L, Tsantoulas D, Mieli- Vergani G, Bianchi FB, Vergani D. Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51. Int J Immunopathol Pharmacol. 2004 Jan-Apr;17(1):83-92. PubMed PMID: 15000871. 138: Bogdanos DP, Bianchi I, Ma Y, Mitry RR, Mieli-Vergani G, Vergani D. Targets of antibodies to soluble liver antigen in patients with autoimmune hepatitis. Clin Chem. 2004 Mar;50(3):682-3; author reply 683-4. PubMed PMID: 14981048. 139: Vergani D, Bogdanos DP, Baum H. Unusual suspects in primary biliary cirrhosis. Hepatology. 2004 Jan;39(1):38-41. Review. PubMed PMID: 14752820. 140: Bogdanos DP, Baum H, Butler P, Rigopoulou EI, Davies ET, Ma Y, Burroughs AK, Vergani D. Association between the primary biliary cirrhosis specific anti-sp100

antibodies and recurrent urinary tract infection. Dig Liver Dis. 2003 Nov;35(11):801-5. PubMed PMID: 14674671. 141: Bogdanos DP, Baum H, Grasso A, Okamoto M, Butler P, Ma Y, Rigopoulou E, Montalto P, Davies ET, Burroughs AK, Vergani D. Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. J Hepatol. 2004 Jan;40(1):31-9. PubMed PMID: 14672611. 142: Bogdanos DP, Baum H, Vergani D. Antimitochondrial and other autoantibodies. Clin Liver Dis. 2003 Nov;7(4):759-77, vi. Review. PubMed PMID: 14594130. 143: Bogdanos DP, McFarlane IG. Cytochrome P450 2A6 meets P450 2D6: an enigma of viral infections and autoimmunity. J Hepatol. 2003 Nov;39(5):860-3. Review. PubMed PMID: 14568272. 144: Gregorio GV, Choudhuri K, Ma Y, Pensati P, Iorio R, Grant P, Garson J,

Bogdanos DP, Vegnente A, Mieli-Vergani G, Vergani D. Mimicry between the hepatitis C virus polyprotein and antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis C virus infection. Clin Exp Immunol. 2003 Sep;133(3):404-13. PubMed PMID: 12930368; PubMed Central PMCID: PMC1808793. 145: Hannam S, Bogdanos DP, Davies ET, Hussain MJ, Portmann BC, Mieli-Vergani G, Vergani D. Neonatal liver disease associated with placental transfer of anti-mitochondrial antibodies. Autoimmunity. 2002 Dec;35(8):545-50. PubMed PMID: 12765481. 146: Vergani D, Bogdanos DP. Positive markers in AMA-negative PBC. Am J

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Gastroenterol. 2003 Feb;98(2):241-3. PubMed PMID: 12591035. 147: Kerkar N, Choudhuri K, Ma Y, Mahmoud A, Bogdanos DP, Muratori L, Bianchi F, Williams R, Mieli-Vergani G, Vergani D. Cytochrome P4502D6(193-212): a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease. J Immunol. 2003 Feb 1;170(3):1481-9. PubMed PMID: 12538711. 148: Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G. Pathogenesis of autoimmune hepatitis. Clin Liver Dis. 2002 Aug;6(3):727-37. Review. PubMed PMID: 12362577. 149: Ma Y, Thomas MG, Okamoto M, Bogdanos DP, Nagl S, Kerkar N, Lopes AR, Muratori L, Lenzi M, Bianchi FB, Mieli-Vergani G, Vergani D. Key residues of a major cytochrome P4502D6 epitope are located on the surface of the molecule. J Immunol. 2002 Jul 1;169(1):277-85. PubMed PMID: 12077255.

150: Wen L, Ma Y, Bogdanos DP, Wong FS, Demaine A, Mieli-Vergani G, Vergani D. Pediatric autoimmune liver diseases: the molecular basis of humoral and cellular immunity. Curr Mol Med. 2001 Jul;1(3):379-89. Review. PubMed PMID: 11899084. 151: Ma Y, Okamoto M, Thomas MG, Bogdanos DP, Lopes AR, Portmann B, Underhill J, Dürr R, Mieli-Vergani G, Vergani D. Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease. Hepatology. 2002 Mar;35(3):658-64. PubMed PMID: 11870381. 152: Bogdanos DP, Baum H, Sharma UC, Grasso A, Ma Y, Burroughs AK, Vergani D. Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis. J Hepatol. 2002 Jan;36(1):14-21. PubMed PMID: 11804659. 153: Bogdanos DP, Mieli-Vergani G, Vergani D. Liver-kidney microsomal

antibody-positive autoimmune hepatitis in the United States. Am J Gastroenterol. 2001 Dec;96(12):3447-8. PubMed PMID: 11774973. 154: Bogdanos DP, Choudhuri K, Vergani D. Molecular mimicry and autoimmune liver disease: virtuous intentions, malign consequences. Liver. 2001 Aug;21(4):225-32. Review. PubMed PMID: 11454184. 155: Baum H, Bogdanos DP, Vergani D. Antibodies to Clp protease in primary biliary cirrhosis: possible role of a mimicking T-cell epitope. J Hepatol. 2001 May;34(5):785-7. PubMed PMID: 11434633. 156: Bogdanos DP, Mieli-Vergani G, Vergani D. Virus, liver and autoimmunity. Dig Liver Dis. 2000 Jun-Jul;32(5):440-6. PubMed PMID: 11030191. 157: Bogdanos DP, Muratori L, Bianchi FB, Vergani D. Hepatitis C virus and autoimmunity. Hepatology. 2000 Jun;31(6):1380. PubMed PMID: 10866525.

Additional Publications not deposited in Pubmed 158: Mavropoulos A, Koutsoumpas A, Bogdanos DP, Sakkas LI. The role of p38 MAP in autoimmune diseases. Inter Trends Immun 2014; 3(2) 2015, 1-17 160: Smyk DS, Bogdanos DP, Rigopoulou EI. Risk factors for autoimmune hepatitis. From genes and pregnancy to vaccination and pollutants. Immuno-Gastroenterology 2013, 2(1); 29-37

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161: Roggenbuck D, Reinhold D, Wex T, von Arnim U, Malfertheiner P, Sturn A, Werner L, Bogdanos DP, Laass MW, Conrad K. The Authors’ reply. Gut 2012 61: 164-165; doi: 10.1136/gut.2010.237214 162: Smyk DS, Rigopouloy EI, Zen Y, Koutsoumpas A, Baum H, Bogdanos DP. Infectious triggers of primary biliary cirrhosis: do we know enough? Curr Trends Immunol 2010 11: 35-49

163: Bogdanos DP, Christen U. Autoimmune hepatitis: an update on current animal models.The Open Pathology Journal 2008;2:39-45 164: Bogdanos DP, Vergani D, Mieli-Vergani G. Overlap syndromes from pediatrics to adulthood. J Gastroenterol Hepatol 2004;19:S284-6

Chapters in Books

165: Bogdanos DP, Smyk DS, Sakkas LI, Shoenfeld Y. Chapter 9: Infection and

Autoimmunity, 2nd edition, Y Shoenfeld, N Agmon-Levin, N Rose, 01/2015:: pp149-162; Academic Press, 2015

166: Bogdanos DP, Leung PSC, Gershwin ME. Chapter 87: Liver and biliary tract. In Mucosal Immunology 4th Edition, Vol 2 Editors Jiri Mestecky, Warren Strober, Michael W. Russell, Brian L. Kelsall, Hide Cheroutre, Bart Lambrecht, pp 1695-1717, Academic Press, 2015

167: Smyk DS, Sakkas LI, Shoenfeld Y, Bogdanos DP. Hepatitis B Vaccination and Autoimmunity in Vaccines and autoimmunity, pp.147-162 Editors: Yehuda Shoenfeld, Nancy Agmon-Levin, Lucija Tomljenovic Publisher: Wiley-Blackwell, Oxford 2014

168: Antico A, Tampoia M, Bogdanos D, Tozzolli R. Gastric autoantibodies. pp 359-364. In Autoantibodies 3rd Edition. Editors: Y Shoenfeld, PL Meroni, ME Gershwin. Elsevier, Oxford, 2014

169: Conrad K, Bogdanos D, Roggenbuck D. Antipancreatic antibodies.Chapter 51, pp.433-440. In Autoantibodies 3rd Edition. Editors: Y Shoenfeld, PL Meroni, ME Gershwin. Elsevier, Oxford, 2014

170: Bogdanos DP, Rigamonti C, Milkiewicz P, Rigopoulou EI, Burroughs AK. Emerging issues in the immunopathogenesis, diagnosis and clinical management of primary biliary cirrhosis associated with systemic sclerosis. In ‘Systemic Sclerosis’ Editor: T. Radstake; Publishers: Intech; ISBN 978-953-307-869-4, 2011

171: Bogdanos DP, Conrad K, Smyk DS, Rigopoulou EI, Forbes A. Novel autoantibody markers in autoimmune gastrointestinal and liver diseases. pp288-301 Editors K. Conrad, Pabst Science Publishers, Lengerich, Germany, 2011 From Prediction to Prevention of Autoimmune Diseases. by K. Conrad, E. K. L. Chan, M. J. Fritzler, R.L. Humbel, P. L. Meroni, Y. Shoenfeld (Eds.)

172. L. Komorowski, D.P Bogdanos, C. Probst, C. Dähnrich, A. Rosemann, W. Schlumberger, W. Stöcker: Detection of primary biliary cirrhosis-associated anti-mitochondrial antibodies using an improved test system: Anti-M2/BPO ELISA. From Etiopathogenesis to the Prediction of Autoimmune Diseases: Relevance of

Autoantibodies Chapter 6.2 Gastrointestinal and Liver Diseases (in press) K. Conrad, E.K.L. Chan, M.J. Fritzler, U. Sack, Y. Shoenfeld, A.S. Wiik (Eds.)

173. W. Meyer, T. Scheper, N. Janssen, L. Komorowski, C. Probst, W. Schlumberger, D.P Bogdanos, W. Stöcker: A comprehensive line immunoassay for the detection of autoantibodies in primary biliary cirrhosis (PBC) From Etiopathogenesis to the Prediction of Autoimmune Diseases: Relevance of Autoantibodies Chapter 6.2 Gastrointestinal and Liver Diseases K. Conrad, E.K.L. Chan, M.J. Fritzler, U. Sack, Y. Shoenfeld, A.S. Wiik (Eds.) Pabst Science Publishers, Lengerich, Germany

174. Ma Y, Longhi MS, Bogdanos DP, Mieli-Vergani G, Vergani D. Autoreactive T cells: any evidence in autoimmune liver disease? In “Autoimmune liver Diseases”. Falk Symposium 142, Kluwer Academic Publishers, Dordrecht, pages 49-58, 2004

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175. Bogdanos DP, Baum H, Vergani D. Antimitochondrial and other autoantibodies. In “Primary biliary cirrhosis”. Gitlin N, Heathcote EJ, Eds. Saunders, Philadelphia, USA. Pages 759-77, 2003

176. Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G. (2002) Role of molecular mimicry in viral and autoimmune Liver Disease. In “Autoimmune diseases in pediatric gastroenterology ". Branski D, Hadziselimovic F, Harms K, Lentze M, Eds. Kluwer Academic Publishers, Dordrecht. Pages 9-12, 2002

177. Vergani D, Choudhuri K, Bogdanos DP, Mieli-Vergani G. Pathogenesis of autoimmune hepatitis. In “Autoimmune hepatitis ". Gitlin N, Czaja A, Eds. Saunders, Philadelphia, USA. Pages 439-50, 2002

Publication in Hellenic Journals 178 ΣΑΚΚΑΣ ΛΙ, ΜΑΥΡΟΠΟΥΛΟΣ Α, ΜΠΟΓΔΑΝΟΣ ΔΠ, Meditterranean J Rheumatolog-

Ελληνική Ρευματολογία, Mediterr J Rheumatol 2015; 26(1): 64-67 179. ΡΗΓΟΠΟΥΛΟΥ ΕΙ, ΜΠΟΓΔΑΝΟΣ ΔΠ.Νεότερα δεδομένα στην επιδημιολογία,

παθογένεια και θεραπεία της πρωτοπαθούς χολικής κίρρωσης.Ελληνική Ιατρική

2001;67 (sup1):93-100 179. ΛΑΠΠΑΣ Α, ΜΠΟΓΔΑΝΟΣ Δ, ΚΟΝΣΤΑΝΤΙΝΟΥ Γ, ΜΠΟΚΟΛΑΣ Γ, ΙΩΑΝΝΙΔΗΣ Κ,

ΜΠΟΥΡΑ Π, ΚΟΥΝΤΟΥΡΑΣ Ι. Η αξία της δοκιμασίας ουρεάσης (CLO) σιάλου-οδοντικής πλάκας στην αντιμετώπιση ασθενών με πεπτικό έλκος και Helicobacter pylori λοίμωξη. Αρχεία Ελληνικής Ιατρικής 1997;14:330

Monographies 180. Bogdanos DP. Autoimmune Hepatitis: Confirmation of the diagnosis – Interprenting the Serology. pp.67-92 ‘Autoimmune hepatitis – a guide for practising physicians’ Editors: J Heathcote & G Hirschfield. Humana Press, 2011 181. Bogdanos Dimitrios-Petrou, Molecular mimicry in primary biliary cirrhosis and other hepatic and extra-hepatic diseases: PhD Thesis, Faculty of medicine, University of London, May 2005, pages 256 Career Metric evolution of Publications in Pubmed At the time I have submitted

5) an application for a non-tenure position of Assistant Professor of Medicine (July 2008), I had published 55 articles deposited in PubMed.

6) At the time I joined the Division of Medicine (September 2011), the total number of publications deposited in PubMed was 72

7) When I submitted my application for the tenure position as an Assistant Professor of Internal Medicine (February 2014), I had published 126 papers listed in PubMed library

8) My current application as an Associate Professor in Internal Medicine and Autoimmune Diseases is supported by 158 articles deposited in Pubmed

BEST IMPACT FACTOR JOURNAL PUBLICATIONS (IF*>6)

12. Gastroenterology (2 articles) 13. Gut (2 articles) 14. Hepatology (7 articles) 15. J of Hepatology (6 articles) 16. American J Gastroenterology (4 articles) 17. Clinical Infectious Diseases (2 articles) 18. J Autoimmunity (5 articles) 19. Arthritis & Rheumatology (1 article)

IF: 16.7 IF: 14.7 IF: 11.1 IF: 11.3 IF: 10.8 IF: 8.9 IF: 8.4 IF: 7.8

D-P Bogdanos, CV

43

20. Autoimmunity Reviews (8 articles) 21. Clinical Gastroenterology Hepatology (1 article) 22. J Crohn’s Colitis (2 articles)

IF: 7.9 IF: 7.9 IF: 6.2

IF* of 2014

Total number of publications IF>6: 40 Median Journal’s IF of publications with an IF>6: 8.4 Citations Perish or Publish Citations: 5013 Google Scholar Citations: 4928 Scopus Citations: 4008 h-index: 39 (Publish or Perish); 39 (Google Scholar); 37 (Scopus)

Google Scholar List of Papers and Citations (as deposited in Google Scholar)

Title Citations Year

Impairment of CD4+ CD25+ regulatory T-cells in autoimmune liver disease MS Longhi, Y Ma, DP Bogdanos, P Cheeseman, G Mieli-Vergani, ... Journal of hepatology 41 (1), 31-37

264 2004

Autoimmune hepatitis D Vergani, MS Longhi, DP Bogdanos, Y Ma, G Mieli-Vergani Seminars in immunopathology 31 (3), 421-435

203 2009

Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease Y Ma, M Okamoto, MG Thomas, DP Bogdanos, AR Lopes, B Portmann, ... Hepatology 35 (3), 658-664

193 2002

Cytochrome P4502D6193–212: a new immunodominant epitope and target of virus/self cross-reactivity in liver kidney microsomal autoantibody type 1-positive liver disease N Kerkar, K Choudhuri, Y Ma, A Mahmoud, DP Bogdanos, L Muratori, ... The Journal of Immunology 170 (3), 1481-1489

168 2003

Autoimmune liver serology: current diagnostic and clinical challenges DP Bogdanos, P Invernizzi, IR Mackay, D Vergani World journal of gastroenterology: WJG 14 (21), 3374

165 2008

Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis MS Longhi, Y Ma, RR Mitry, DP Bogdanos, M Heneghan, P Cheeseman, ... Journal of autoimmunity 25 (1), 63-71

149 2005

Molecular mimicry and autoimmune liver disease: virtuous intentions, malign consequences DP Bogdanos, K Choudhuri, D Vergani Liver 21 (4), 225-232

143 2001

D-P Bogdanos, CV

44

Pathogenesis of autoimmune hepatitis D Vergani, K Choudhuri, DP Bogdanos, G Mieli-Vergani Clinics in liver disease 6 (3), 727-737

131 2002

Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2 Y Ma, DP Bogdanos, MJ Hussain, J Underhill, S Bansal, MS Longhi, ... Gastroenterology 130 (3), 868-882

124 2006

Twin studies in autoimmune disease: genetics, gender and environment DP Bogdanos, DS Smyk, EI Rigopoulou, MG Mytilinaiou, MA Heneghan, ... Journal of autoimmunity 38 (2), J156-J169

123 2012

Antimitochondrial and other autoantibodies DP Bogdanos, H Baum, D Vergani Clinics in Liver Disease 7 (4), 759-777

100 2003

Mimicry between the hepatitis C virus polyprotein and antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis C virus infection GV Gregorio, K Choudhuri, Y Ma, P Pensati, R Iorio, P Grant, J Garson, ... Clinical & Experimental Immunology 133 (3), 404-413

99 2003

Prevalence and clinical significance of isotype specific antinuclear antibodies in primary biliary cirrhosis EI Rigopoulou, ET Davies, A Pares, K Zachou, C Liaskos, DP Bogdanos, ... Gut 54 (4), 528-532

97 2005

Autoantibodies and their antigens in autoimmune hepatitis. DP Bogdanos, G Mieli-Vergani, D Vergani Seminars in liver disease 29 (3), 241-253

94 2009

Cytochrome P450IID6‐specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2 MS Longhi, MJ Hussain, DP Bogdanos, A Quaglia, G Mieli‐Vergani, Y Ma, ... Hepatology 46 (2), 472-484

91 2007

Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis DP Bogdanos, H Baum, A Grasso, M Okamoto, P Butler, Y Ma, ... Journal of hepatology 40 (1), 31-39

89 2004

Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus-infected patients is associated with the possession of HLA B51 DP Bogdanos, M Lenzi, M Okamoto, EI Rigopoulou, P Muratori, Y Ma, ... International journal of immunopathology and pharmacology 17 (1), 83-92

76 2004

Primary biliary cirrhosis is characterized by IgG3 antibodies cross‐reactive with the major mitochondrial autoepitope and its Lactobacillus mimic DP Bogdanos, H Baum, M Okamoto, P Montalto, UC Sharma, ... Hepatology 42 (2), 458-465

74 2005

D-P Bogdanos, CV

45

PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis H Liu, GL Norman, Z Shums, HJ Worman, EL Krawitt, N Bizzaro, ... Journal of autoimmunity 35 (4), 436-442

73 2010

Disease-specific autoantibodies in primary biliary cirrhosis DP Bogdanos, L Komorowski Clinica Chimica Acta 412 (7), 502-512

69 2011

Virus, liver and autoimmunity DP Bogdanos, G Mieli-Vergani, D Vergani Digestive and Liver Disease 32 (5), 440-446, 2000

67 2000

Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis DP Bogdanos, H Baum, UC Sharma, A Grasso, Y Ma, AK Burroughs, ... Journal of Hepatology 36 (1), 14-21, 2002

64 2002

New ELISA for Detecting Primary Biliary Cirrhosis–Specific Antimitochondrial Antibodies C Dähnrich, A Pares, L Caballeria, A Rosemann, W Schlumberger, ... Clinical Chemistry 55 (5), 978-985, 2009

61 2009

Bacteria and primary biliary cirrhosis DP Bogdanos, D Vergani Clinical reviews in allergy & immunology 36 (1), 30-39, 2009

60 2009

Susceptibility to thyroid disorders in hepatitis C L Muratori, DP Bogdanos, P Muratori, M Lenzi, A Granito, Y Ma, ... Clinical Gastroenterology and Hepatology 3 (6), 595-603, 2005

57 2005

Positive markers in AMA-negative PBC D Vergani, DP Bogdanos The American journal of gastroenterology 98 (2), 241-243, 2003

56 2003

Pediatric autoimmune liver diseases the molecular basis of humoral and cellular immunity LI Wen, Y Ma, DP Bogdanos, F Wong, G Mieli-Vergani, D Vergani Current Molecular Medicine 1 (3), 379-389, 2001

56 2001

Key residues of a major cytochrome P4502D6 epitope are located on the surface of the molecule Y Ma, MG Thomas, M Okamoto, DP Bogdanos, S Nagl, N Kerkar, ... The Journal of Immunology 169 (1), 277-285, 2002

55 2002

Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis EI Rigopoulou, ET Davies, DP Bogdanos, C Liaskos, M Mytilinaiou, ... Liver International 27 (9), 1226-1231, 2007

52 2007

Association between the primary biliary cirrhosis specific anti-sp100 antibodies and recurrent urinary tract infection DP Bogdanos, H Baum, P Butler, EI Rigopoulou, ET Davies, Y Ma, ...

51 2003

D-P Bogdanos, CV

46

Digestive and Liver Disease 35 (11), 801-805, 2003

Does cross-reactivity between mycobacterium avium paratuberculosis and human intestinal antigens characterize Crohn’s disease? D Polymeros, DP Bogdanos, R Day, D Arioli, D Vergani, A Forbes Gastroenterology 131 (1), 85-96, 2006

50 2006

Infectome: a platform to trace infectious triggers of autoimmunity DP Bogdanos, DS Smyk, P Invernizzi, EI Rigopoulou, M Blank, S Pouria, ... Autoimmunity reviews 12 (7), 726-740, 2013

49 2013

Disease-specific cross-reactivity between mimicking peptides of heat shock protein of Mycobacterium gordonae and dominant epitope of E2 subunit of pyruvate dehydrogenase is common in Spanish but not British patients with primary biliary cirrhosis DP Bogdanos, A Pares, H Baum, L Caballeria, EI Rigopoulou, Y Ma, ... Journal of autoimmunity 22 (4), 353-362, 2004

49 2004

A study of molecular mimicry and immunological cross-reactivity between hepatitis B surface antigen and myelin mimics DP Bogdanos, H Smith, Y Ma, H Baum, G Mieli-Vergani, D Vergani Journal of Immunology Research 12 (3), 217-224, 2005

48 2005

Extensive homology between the major immunodominant mitochondrial antigen in primary biliary cirrhosis and Helicobacter pylori does not lead to immunological cross-reactivity DP Bogdanos, H Baum, F Gunsar, D Arioli, D Polymeros, Y Ma, ... Scandinavian journal of gastroenterology 39 (10), 981-987, 2004

48 2004

Autoimmunity and environment: am I at risk? D Smyk, EI Rigopoulou, H Baum, AK Burroughs, D Vergani, ... Clinical reviews in allergy & immunology 42 (2), 199-212, 2012

46 2012

Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease D Roggenbuck, D Reinhold, T Wex, A Goihl, U von Arnim, P Malfertheiner, ... Clinica chimica acta 412 (9), 718-724, 2011

41 2011

Anti‐gp210 antibody mirrors disease severity in primary biliary cirrhosis DP Bogdanos, C Liaskos, A Pares, G Norman, EI Rigopoulou, ... Hepatology 45 (6), 1583-1583, 2007

40 2007

Primary biliary cirrhosis following Lactobacillus vaccination for recurrent vaginitis D Bogdanos, T Pusl, C Rust, D Vergani, U Beuers Journal of hepatology 49 (3), 466-473, 2008

39 2008

Unusual suspects in primary biliary cirrhosis D Vergani, DP Bogdanos, H Baum Hepatology 39 (1), 38-41, 2004

39 2004

Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies

38 2011

D-P Bogdanos, CV

47

DP Bogdanos, EI Rigopoulou, DS Smyk, D Roggenbuck, D Reinhold, ... Autoimmunity reviews 11 (2), 143-148, 2011

Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: lost and found EI Rigopoulou, D Roggenbuck, DS Smyk, C Liaskos, MG Mytilinaiou, ... Autoimmunity reviews 12 (2), 260-269, 2012

37 2012

Enzymes as target antigens of liver-specific autoimmunity: the case of cytochromes P450s DP Bogdanos, GN Dalekos Current medicinal chemistry 15 (22), 2285-2292, 2008

36 2008

New platform technology for comprehensive serological diagnostics of autoimmune diseases A Willitzki, R Hiemann, V Peters, U Sack, P Schierack, S Rödiger, ... Clinical and Developmental Immunology 2012, 2012

35 2012

Anti-mitochondrial antibody immunofluorescent titres correlate with the number and intensity of immunoblot-detected mitochondrial bands in patients with primary biliary cirrhosis EI Rigopoulou, DP Bogdanos, C Liaskos, A Koutsoumpas, H Baum, ... Clinica Chimica Acta 380 (1), 118-121, 2007

35 2007

Type 1 autoimmune pancreatitis Y Zen, DP Bogdanos, S Kawa Orphanet J Rare Dis 6 (1), 82, 2011

33 2011

Primary biliary cirrhosis: family stories D Smyk, E Cholongitas, S Kriese, EI Rigopoulou, DP Bogdanos Autoimmune diseases 2011, 2011

33 2011

Origin of cross‐reactive autoimmunity in primary biliary cirrhosis DP BOGDANOS, D VERGANI Liver International 26 (6), 633-635, 2006

33 2006

The role of E. coli infection in the pathogenesis of primary biliary cirrhosis DP Bogdanos, H Baum, D Vergani, AK Burroughs Disease markers 29 (6), 301-311, 2010

31 2010

Non-organ-specific autoantibodies in hepatitis C virus infection: do they matter? DP Bogdanos, G Mieli-Vergani, D Vergani Clinical Infectious Diseases 40 (4), 508-510, 2005

28 2005

Antibodies to soluble liver antigen and α-enolase in patients with autoimmune hepatitis DP Bogdanos, D Gilbert, I Bianchi, S Leoni, RR Mitry, Y Ma, ... Journal of autoimmune diseases 1 (1), 4, 2004

28 2004

Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn’s disease DP Bogdanos, D Roggenbuck, D Reinhold, T Wex, P Pavlidis, ... BMC gastroenterology 12 (1), 102, 2012

26 2012

D-P Bogdanos, CV

48

Urinary tract infection as a risk factor for autoimmune liver disease: from bench to bedside DS Smyk, DP Bogdanos, S Kriese, C Billinis, AK Burroughs, ... Clinics and research in hepatology and gastroenterology 36 (2), 110-121, 2012

25 2012

Antibodies to Clp protease in primary biliary cirrhosis: possible role of a mimicking T-cell epitope H Baum, DP Bogdanos, D Vergani Journal of hepatology 34 (5), 785-787, 2001

25 2001

IgM predominance in autoimmune disease: genetics and gender C Duarte-Rey, DP Bogdanos, PSC Leung, JM Anaya, ME Gershwin Autoimmunity reviews 11 (6), A404-A412, 2012

24 2012

Smoking as a risk factor for autoimmune liver disease: what we can learn from primary biliary cirrhosis DS Smyk, EI Rigopoulou, L Muratori, AK Burroughs, DP Bogdanos Ann Hepatol 11 (1), 7-14, 2012

24 2012

Primary biliary cirrhosis specific antinuclear antibodies in patients from Spain DP Bogdanos, A Pares, J Rodés, D Vergani The American journal of gastroenterology 99 (4), 763-764, 2004

24 2004

PBC triggers in water reservoirs, coal mining areas and waste disposal sites: from Newcastle to New York D Smyk, MG Mytilinaiou, EI Rigopoulou, DP Bogdanos Disease markers 29 (6), 337-344, 2010

23 2010

Ileal inflammation may trigger the development of GP2-specific pancreatic autoantibodies in patients with Crohn’s disease P Pavlidis, O Romanidou, D Roggenbuck, MG Mytilinaiou, F Al-Sulttan, ... Clinical and Developmental Immunology 2012, 2012

22 2012

Autoantibodies in autoimmune pancreatitis DS Smyk, EI Rigopoulou, AL Koutsoumpas, S Kriese, AK Burroughs, ... International journal of rheumatology 2012, 2012

21 2012

Sex differences associated with primary biliary cirrhosis DS Smyk, EI Rigopoulou, A Pares, C Billinis, AK Burroughs, L Muratori, ... Clinical and developmental immunology 2012, 2012

21 2012

Epstein-barr virus as a trigger of autoimmune liver diseases EI Rigopoulou, DS Smyk, CE Matthews, C Billinis, AK Burroughs, M Lenzi, ... Advances in virology 2012, 2012

20 2012

Immunopathogenesis of primary biliary cirrhosis: an old wives’ tale DS Smyk, EI Rigopoulou, A Lleo, RD Abeles, A Mavropoulos, C Billinis, ... Immunity & Ageing 8 (1), 12, 2011

20 2011

Anti-Helicobacter pylori antibody responses specific for VacA do not trigger primary biliary cirrhosis-specific antimitochondrial antibodies

20 2009

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A Koutsoumpas, M Mytilinaiou, D Polymeros, GN Dalekos, DP Bogdanos European journal of gastroenterology & hepatology 21 (10), 1220, 2009

Disease‐specific autoantibodies in patients with acute liver failure: The King's College London Experience W Bernal, F Meda, Y Ma, DP Bogdanos, D Vergani Hepatology 47 (3), 1096-1097, 2008

20 2008

Cytochrome P450 2A6 meets P450 2D6: an enigma of viral infections and autoimmunity DP Bogdanos, IG McFarlane Journal of hepatology 39 (5), 860-863, 2003

20 2003

Vitamin D in autoimmune liver disease DS Smyk, T Orfanidou, P Invernizzi, DP Bogdanos, M Lenzi Clinics and research in hepatology and gastroenterology 37 (5), 535-545, 2013

19 2013

Primary biliary cirrhosis and the nuclear pore complex C Duarte-Rey, D Bogdanos, CY Yang, K Roberts, PSC Leung, JM Anaya, ... Autoimmunity reviews 11 (12), 898-902, 2012

19 2012

Molecular mimicry rather than identity breaks T-cell tolerance in the CYP2D6 mouse model for human autoimmune hepatitis J Ehser, M Holdener, S Christen, M Bayer, JM Pfeilschifter, E Hintermann, ... Journal of autoimmunity 42, 39-49, 2013

18 2013

Glycoprotein 2 antibodies in Crohn’s disease D Roggenbuck, D Reinhold, L Werner, P Schierack, DP Bogdanos, ... Adv Clin Chem 60, 187-208, 2013

18 2013

Diagnostic and clinical utility of antibodies against the nuclear body promyelocytic leukaemia and Sp100 antigens in patients with primary biliary cirrhosis MG Mytilinaiou, W Meyer, T Scheper, EI Rigopoulou, C Probst, ... Clinica Chimica Acta 413 (15), 1211-1216, 2012

18 2012

Specificity of anti-sp100 antibody for primary biliary cirrhosis. DP Bogdanos, D Vergani, P Muratori, L Muratori, FB Bianchi Scandinavian journal of gastroenterology 39 (4), 405-6; author reply 407, 2004

18 2004

p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: lessons to learn from ANCA vasculitis and pemphigus vulgaris A Mavropoulos, T Orfanidou, C Liaskos, DS Smyk, C Billinis, M Blank, ... Autoimmunity reviews 12 (5), 580-590, 2013

16 2013

Antibodies to glycoprotein 2 (GP2) in patients with inflammatory bowel diseases from UK P Pavlidis, A Forbes, DP Bogdanos Clinica Chimica Acta 412 (11), 1163-1164, 2011

16 2011

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50

Diagnostic relevance of anti-filamentous actin antibodies in autoimmune hepatitis C Liaskos, DP Bogdanos, ET Davies, GN Dalekos Journal of clinical pathology 60 (1), 107-108, 2007

16 2007

Anti-mitochondrial antibodies in patients with systemic lupus erythematosus: revealing the unforeseen DP Bogdanos, C Liaskos, EI Rigopoulou, GN Dalekos Clinica Chimica Acta 373 (1), 183-184, 2006

16 2006

Borrelia Burgdorferi: a new self-mimicking trigger in primary biliary cirrhosis DP Bogdanos, A Koutsoumpas, H Baum, D Vergani Digestive and Liver Disease 38 (10), 781-782, 2006

16 2006

Viral/self-mimicry and immunological cross-reactivity as a trigger of hepatic C virus associated autoimmune diabetes DP Bogdanos, EI Rigopoulou Diabetes research and clinical practice 77 (1), 155-156, 2007

15 2007

Alcohol dehydrogenase: an autoantibody target in patients with alcoholic liver disease Y Ma, M Meregalli, S Hodges, N Davies, DP Bogdanos, S Fargion, ... International journal of immunopathology and pharmacology 18 (1), 173-182, 2005

15 2005

Different immunogenetic background in autoimmune hepatitis type 1, type 2 and autoimmune sclerosing cholangitis JA Underhill, Y Ma, DP Bogdanos, P Cheeseman, G Mieli-Vergani, ... Journal of Hepatology 36, 156, 2002

15 2002

Neonatal liver disease associated with placental transfer of anti-mitochondrial antibodies S Hannam, DP Bogdanos, ET Davies, MJ Hussain, BC Portmann, ... Autoimmunity 35 (8), 545-550, 2002

15 2002

Development of antimitochondrial antibodies in patients with autoimmune hepatitis: art of facts or an artifact? C Liaskos, DP Bogdanos, EI Rigopoulou, GN Dalekos Journal of gastroenterology and hepatology 22 (3), 454-455, 2007

14 2007

Crohn’s disease specific pancreatic antibodies: clinical and pathophysiological challenges D Roggenbuck, D Reinhold, P Schierack, DP Bogdanos, K Conrad, ... Clinical Chemistry and Laboratory Medicine 52 (4), 483-494, 2014

13 2014

Liver immunology DP Bogdanos, B Gao, ME Gershwin Comprehensive Physiology, 2013

13 2013

Standardization of automated interpretation of immunofluorescence tests D Roggenbuck, R Hiemann, D Bogdanos, D Reinhold, K Conrad Clinica Chimica Acta, 168-169, 2013

13 2013

Primary biliary cirrhosis associated with systemic sclerosis: diagnostic and 13 2011

D-P Bogdanos, CV

51

clinical challenges C Rigamonti, DP Bogdanos, MG Mytilinaiou, DS Smyk, EI Rigopoulou, ... International journal of rheumatology 2011, 2011

Authors' response: antibodies to GP2, the major zymogen granule membrane glycoprotein, are specific for Crohn's disease and may reflect treatment response D Roggenbuck, D Reinhold, T Wex, U von Arnim, P Malfertheiner, ... Gut, gut. 2010.237214, 2011

13 2011

Targets of antibodies to soluble liver antigen in patients with autoimmune hepatitis DP Bogdanos, I Bianchi, Y Ma, RR Mitry, G Mieli-Vergani, D Vergani Clinical chemistry 50 (3), 682-684, 2004

13 2004

Tracing environmental markers of autoimmunity: introducing the infectome DP Bogdanos, DS Smyk, P Invernizzi, EI Rigopoulou, M Blank, L Sakkas, ... Immunologic research 56 (2-3), 220-240, 2013

12 2013

Primary biliary cirrhosis-specific autoantibodies in patients with systemic sclerosis MG Mytilinaiou, DP Bogdanos Digestive and Liver Disease 41 (12), 916, 2009

12 2009

Hepatitis C virus and autoimmunity. DP Bogdanos, L Muratori, FB Bianchi, D Vergani Hepatology (Baltimore, Md.) 31 (6), 1380-1380, 2000

12 2000

What is new in primary biliary cirrhosis? DP Bogdanos, ME Gershwin Digestive Diseases 30 (Suppl. 1), 20-31, 2012

11 2012

Cytochrome P450 1A2 is a target antigen in hepatitic graft-versus-host disease CG Mullighan, DP Bogdanos, D Vergani, PG Bardy Bone marrow transplantation 38 (10), 703-705, 2006

11 2006

The novel Crohn's disease marker anti-GP2 antibody is associated with ileocolonic location of disease V Somma, H Ababneh, A Ababneh, S Gatti, V Romagnoli, E Bendia, ... Gastroenterology research and practice 2013, 2013

10 2013

Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and review of the literature P Invernizzi, MG Alessio, DS Smyk, A Lleo, A Sonzogni, L Fabris, ... BMC gastroenterology 12 (1), 92, 2012

10 2012

Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease A Koutsoumpas, D Polymeros, Z Tsiamoulos, D Smyk, G Karamanolis, ... Journal of Crohn's and Colitis 5 (2), 101-109, 2011

10 2011

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Self-mimicking autoimmune domains of hepatitis C virus core antigen DP Bogdanos, EI Rigopoulou Vaccine 24 (37), 6173-6174, 2006

10 2006

Non—Organ-Specific Autoantibodies in Children with Chronic Hepatitis C Virus Infection DP Bogdanos, G Mieli-Vergani, D Vergani Clinical infectious diseases 38 (10), 1505-1505, 2004

10 2004

Diagnostic and clinical significance of anti-centromere antibodies in primary biliary cirrhosis R Liberal, CR Grant, L Sakkas, N Bizzaro, DP Bogdanos Clinics and research in hepatology and gastroenterology 37 (6), 572-585, 2013

9 2013

PR3-ANCA: a promising biomarker for ulcerative colitis with extensive disease M Mahler, DP Bogdanos, P Pavlidis, MJ Fritzler, E Csernok, ... Clinica Chimica Acta 424, 267-273, 2013

9 2013

The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis A Mavropoulos, EI Rigopoulou, C Liaskos, DP Bogdanos, LI Sakkas Clinical and Developmental Immunology 2013, 2013

9 2013

Development of a recombinant cell-based indirect immunofluorescence assay (RC-IFA) for the determination of autoantibodies against “rings and rods”-associated inosine-5′-monophosphate dehydrogenase 2 in viral hepatitis C C Probst, C Radzimski, IM Blöcker, B Teegen, DP Bogdanos, W Stöcker, ... Clinica Chimica Acta 418, 91-96, 2013

9 2013

Loss of tolerance to one or two major targets in Crohn's disease or just cross-reactivity? D Roggenbuck, D Bogdanos, K Conrad Journal of Crohn's and Colitis 7 (7), e273-e274, 2013

8 2013

Role for mycobacterial infection in pathogenesis of primary biliary cirrhosis? D Smyk, EI Rigopoulou, Y Zen, RD Abeles, C Billinis, A Pares, ... World journal of gastroenterology: WJG 18 (35), 4855, 2012

8 2012

Cross-reactivity to lactobacillus delbrueckii/human pyruvate dehydrogenase complex-E2 characterizes primary biliary cirrhosis. DP Bogdanos, A Grasso, M Okamoto, P Montalto, P Butler, R Williams, ... Hepatology 32 (4), 300A-300A, 2000

8 2000

p38 MAPK signaling in pemphigus: implications for skin autoimmunity A Mavropoulos, T Orfanidou, C Liaskos, DS Smyk, V Spyrou, LI Sakkas, ... Autoimmune diseases 2013, 2013

7 2013

Potential roles for infectious agents in the pathophysiology of primary biliary cirrhosis: what’s new? DS Smyk, EI Rigopoulou, DP Bogdanos

7 2013

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53

Current infectious disease reports 15 (1), 14-24, 2013

LKM1-positive type 2 autoimmune hepatitis following allogenic hematopoietic stem-cell transplantation A Granito, M Stanzani, L Muratori, DP Bogdanos, P Muratori, G Pappas, ... The American journal of gastroenterology 103 (5), 1313-1314, 2008

7 2008

Liver-kidney microsomal antibody-positive autoimmune hepatitis in the United States DP Bogdanos, G Mieli-Vergani, D Vergani The American journal of gastroenterology 96 (12), 3447-3448, 2001

7 2001

Towards systemic sclerosis and away from primary biliary cirrhosis: the case of PTPN22 DS Smyk, MG Mytilinaiou, P Milkiewicz, EI Rigopoulou, P Invernizzi, ... Autoimmunity Highlights 3 (1), 1-9, 2012

6 2012

Anti-SLA antibody is a marker of severity of liver damage in patients with autoimmune liver disease Y Ma, DP Bogdanos, R Willams, G Mieli-Vergani, D Vergani Journal of Hepatology 34, 212, 2001

6 2001

CUZD1 and anti-CUZD1 antibodies as markers of cancer and inflammatory bowel diseases C Liaskos, EI Rigopoulou, T Orfanidou, DP Bogdanos, CN Papandreou Clinical and Developmental Immunology 2013, 2013

5 2013

Familial primary biliary cirrhosis: like mother, like daughter? DS Smyk, EI Rigopoulou, A Pares, MG Mytilinaiou, P Invernizzi, ... Acta gastro-enterologica Belgica 75 (2), 203-209, 2012

5 2012

Human peripheral blood mononuclear cell culture for flow cytometric analysis of phosphorylated mitogen-activated protein kinases A Mavropoulos, D Smyk, EI Rigopoulou, DP Bogdanos Human Cell Culture Protocols, 275-285, 2012

5 2012

1107 PHOSHORYLATION OF P38 MAPK IS DETECTABLE IN NKT CELLS OF PATIENTS WITH AUTOIMMUNE HEPATITIS IN WHOM IT MIRRORS DISEASE ACTIVITY A Mavropoulos, E Spyrou, EI Rigopoulou, D Vergani, GN Dalekos, ... Journal of hepatology 52, S428, 2010

5 2010

Celiac disease‐related autoantibodies in end‐stage autoimmune liver diseases: what is the message? GN Dalekos, DP Bogdanos, J Neuberger Liver International 28 (4), 426-428, 2008

5 2008

Hair dyes as a risk for autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis D Smyk, EI Rigopoulou, N Bizzaro, DP Bogdanos Autoimmunity Highlights 4 (1), 1-9, 2013

4 2013

Rheumatoid arthritis and primary biliary cirrhosis: cause, consequence, or coincidence?

4 2012

D-P Bogdanos, CV

54

DS Smyk, DP Bogdanos, MG Mytilinaiou, AK Burroughs, EI Rigopoulou Arthritis 2012, 2012

TRAF1 gene polymorphism correlates with the titre of Gp210 antibody in patients with primary biliary cirrhosis A Kempinska-Podhorodecka, Z Shums, M Wasilewicz, E Wunsch, ... Clinical and Developmental Immunology 2012, 2012

4 2012

Pancreatic GP2-specific autoantibodies are markers of Crohn's disease P Pavlidis, MG Mytilinaiou, D Roggenbuck, K Conrad, A Forbes, ... Gut 60 (Suppl 1), A212-A213, 2011

4 2011

Glutathionine S-transferase theta 1 (Gstt1) mismatch does not account for post liver transplant de novo autoimmune hepatitis T Grammatikopoulos, MG Mytilinaiou, DP Bogdanos, RJ Thompson, ... Hepatology 50 (4), 635A-636A, 2009

4 2009

Generation of liver/kidney microsomal-1 antibody in HCV infection: The role of molecular mimicry DP Bogdanos, M Lenzi, M Okamoto, Y Ma, L Muratori, R Williams, ... Journal of Hepatology 32, 92, 2000

4 2000

Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides AV Kundzer, MV Volkova, DP Bogdanos, S Rödiger, P Schierack, ... Immunologic research 56 (2-3), 457-464, 2013

3 2013

TRAF1-C5 affects quality of life in patients with primary biliary cirrhosis J Raszeja-Wyszomirska, E Wunsch, A Kempinska-Podhorodecka, ... Clinical and Developmental Immunology 2013, 2013

3 2013

Tuberculosis is not a risk factor for primary biliary cirrhosis: a review of the literature DS Smyk, DP Bogdanos, A Pares, C Liaskos, C Billinis, AK Burroughs, ... Tuberculosis research and treatment 2012, 2012

3 2012

Oral inverted ductal papilloma: Report of a case with immunohistochemical study A Epivatianos, D Antoniades, T Zaraboukas, AK Poulopoulos Open Pathology Journal 2, 1-5, 2008

3 2008

17 Functional impairment of CD25+ CD4+ regulatory T cells characterizes autoimmune hepatitis type 2 Y Ma, MS Longhi, DP Bogdanos, G Mieli-Vergani, D Vergani Hepatology 38, 163, 2003

3 2003

Cross-reactivity between mycobacterium gordonae and PDC-E2, the major target of anti-mitochondrial antibody, is present in Spanish but not British patients with PBC DP Bogdanos, A Pares, UC Sharma, L Caballeria, Y Ma, AK Burroughs, ... Journal of Hepatology 34, 19, 2001

3 2001

Autoantibodies to soluble liver antigen/UGA suppressor tRNA-associated antigenic protein are specific to autoimmune liver disease.

3 2000

D-P Bogdanos, CV

55

Y Ma, M Okamoto, MG Thomas, R Durr, DP Bogdanos, R Williams, ... Hepatology 32 (4), 310A-310A, 2000

Ursodeoxycholic Acid Influences the Expression of but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary Cirrhosis M Milkiewicz, J Kopycińska, A Kempińska-Podhorodecka, T Haas, ... Journal of immunology research 2014, 2014

2 2014

Crohn’s disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: Implications for the pathogenesis of the human disease C Liaskos, V Spyrou, D Roggenbuck, LV Athanasiou, T Orfanidou, ... Autoimmunity 46 (6), 388-394, 2013

2 2013

Development of a recombinant cell-based indirect immunofluorescence assay for the determination of autoantibodies against soluble liver antigen in autoimmune hepatitis C Radzimski, C Probst, B Teegen, K Rentzsch, IM Blöcker, C Dähnrich, ... Clinical and Developmental Immunology 2013, 2013

2 2013

Anti-asialoglycoprotein receptor antibody measured by ELISA is a specific marker of liver autoimmunity and mirrors disease activity in patients with autoimmune hepatitis MG Mytilinaiou, D Roggenbuck, A Grammatikopoulos, E Davies, ... Hepatology 54, 919A-919A, 2011

2 2011

Fetomaternal alloimmunity as a cause of liver disease D Smyk, T Grammatikopoulos, A Daponte, EI Rigopoulou, DP Bogdanos Autoimmunity Highlights 2 (1), 21-28, 2011

2 2011

Infectious triggers of primary biliary cirrhosis: do we know enough? D Smyk, EI Rigopoulou, Z Yoh, A Koutsoumpas, H Baum, DP Bogdanos Current trends in immunology, Volume 11, 35-49, 2010

2 2010

How common are connective tissue disorders in patients with autoimmune hepatitis? EI Rigopoulou, G Dalekos, DP Bogdanos Seminars in arthritis and rheumatism 36 (5), 332, 2007

2 2007

626 In vitro immunosuppressive effect of vitamin D3 in primary biliary cirrhosis C Almerighi, DP Bogdanos, V Cholongitas, I Carey, E Meda, MJ Hussain, ... Journal of Hepatology 44, S232-S233, 2006

2 2006

AUTOIMMUNE LIVER DISEASE/SYSTEMIC LUPUS ERYTHEMATOSUS OVERLAP SYNDROME IN CHILDREN: PH2-10 M Samyn, D Bogdanos, Y Ma, B Portmann, D Vergani, G Mieli-Vergani Journal of Pediatric Gastroenterology and Nutrition 40 (5), 681, 2005

2 2005

Overlap syndromes from pediatrics to adulthood D BOGDANOS, D VERGANI, G MIELI‐VERGANI Journal of Gastroenterology and Hepatology 19 (s7), S284-S286, 2004

2 2004

D-P Bogdanos, CV

56

Immunodominant HLA-A2 restricted CD8 T cell epitope in autoimmune hepatitis type 2. MS Longhi, Y Ma, DP Bogdanos, G Mieli-Vergani, D Vergani Hepatology 40 (4), 422A-422A, 2004

2 2004

P0295 virus-self crossreactivity inducing De Novo autoimmune hepatitis eight-years after liver transplantation DP Bogdanos, Y Ma, N Hadzic, B Portmann, G Mieli-Vergani, D Vergani Journal of Pediatric Gastroenterology and Nutrition 39, S169, 2004

2 2004

Virus/self double reactivity characterises the humoral immune responsein autoimmune hepatitis-2 DP Bogdanos, M Okamoto, Y Ma, R Williams, G Mieli-Vergani, D Vergani Journal of Hepatology 32, 45, 2000

2 2000

Double reactivity to Ecoli/pyruvate dehydrogenase complex-E2characterises primary biliary cirrhosis DP Bogdanos, A Grasso, M Okamoto, P Butler, R Williams, H Baum, ... Journal of Hepatology 32, 39, 2000

2 2000

Cross-reactive immunity explains thyroid autoimmunity in Liver/Kidney Microsomal-1 positive hepatitis C virus infected patients DP Bogdanos, M Lenzi, Y Ma, P Aluigi, F Lari, L Muratori, R Williams, ... Hepatology 30 (4), 460A-460A, 1999

2 1999

Anti-GP2 antibodies in inflammatory bowel disease patients with ileal pouch P Pavlidis, A Forbes, DP Bogdanos Journal of Crohn's and Colitis 7 (11), e602-e603, 2013

1 2013

Polarisation of Major Histocompatibility Complex ii host genotype with pathogenesis of European brown hare syndrome virus C Iacovakis, Z Mamuris, KA Moutou, A Touloudi, AS Hammer, G Valiakos, ...

1 2013

Primary biliary cirrhosis-specific antimitochondrial antibodies in neonatal haemochromatosis DS Smyk, MG Mytilinaiou, T Grammatikopoulos, AS Knisely, ... Clinical and Developmental Immunology 2013, 2013

1 2013

Serum autoantibodies: from identification to clinical relevance DP Bogdanos Clinical and Developmental Immunology 2013, 2013

1 2013

Risk Factors for Autoimmune Hepatitis: From Genes and Pregnancy to Vaccinations and Pollutants DS Smyk, DP Bogdanos, EI Rigopoulou

1 2013

Antibodies to GP2, the major zymogen granule membrane glycoprotein, in inflammatory bowel diseases reply D Roggenbuck, D Reinhold, T Wex, U von Arnim, P Malfertheiner, ... Gut 61 (1), 164-165, 2012

1 2012

Innate Immunity in Gastrointestinal Disorders: Basic and Therapeutic Concepts

1 2012

D-P Bogdanos, CV

57

H Tilg, R Blumberg, S Enders, A Kaser, M Manns Digestive Diseases 30 (Suppl. 1), 1-1, 2012

Emerging issues in the immunopathogenesis, diagnosis and clinical management of primary biliary cirrhosis associated with systemic sclerosis DP Bogdanos, AK Burroughs, C Rigamonti, D Smyk, EI Rigopoulou, ... INTECH Open Access Publisher, 2012

1 2012

Pr3-ANCA in Inflammatory Bowel Disease: A Useful Marker to Differentiate Ulcerative Colitis From Crohn's Disease? M Mahler, A Seaman, DP Bogdanos, P Pavlidis, Z Shums, A Forbes, ... Gastroenterology 140 (5), S-692, 2011

1 2011

P05 B-cell epitope mapping of anti-ro-52 responses in patients with primary biliary cirrhosis MG Mytilinaiou, W Meyer, L Komorowski, C Probst, E Davies, D Vergani, ... Gut 59 (Suppl 2), A13-A14, 2010

1 2010

S1191 Molecular Mimicry and Immunological Crossreactivity Between Measles Virus and Human Intestinal Proteins is Not a Feature of Crohn's Disease AL Koutsoumpas, D Polymeros, Z Tsiamoulos, G Karamanolis, ... Gastroenterology 138 (5), S-200, 2010

1 2010

678 DIAGNOSTIC AND CLINICAL APPLICATION OF A NEW LINE IMMUNOASSAY THAT SIMULTANEOUSLY DETECTS THE MULTIPLE NUCLEAR DOT SPECIFIC ANTIGENS IN PRIMARY BILIARY CIRRHOSIS M Mytilinaiou, W Meyer, A Janssen, P Pavlides, C Probst, NK Gatselis, ... Journal of Hepatology 50, S249, 2009

1 2009

676 FINE SPECIFICITY OF ANTI-NUP62 T-HELPER 1 CELL (TH1) IMMUNE RESPONSE IN PRIMARY BILIARY CIRRHOSIS F Meda, MS Longhi, DP Bogdanos, P Invernizzi, Y Ma, G Mieli-Vergani, ... Journal of Hepatology 50, S248, 2009

1 2009

869 ANALYSIS OF SPECIFIC AUTOANTIBODY PROFILES IN PRIMARY BILIARY LIVER CIRRHOSIS A Janssen, W Meyer, T Scheper, L Komorowski, C Probst, ... Journal of Hepatology 48, S326-S327, 2008

1 2008

[452] CHRONIC HEPATITIS C IS CHARACTERISED BY AN C Liaskos, DP Bogdanos, N Gatselis, M Homer, Z Shums, D Murphy, ... Journal of Hepatology 46, S172, 2007

1 2007

[670] A NEW SUBSTRATE FACILITATES THE DETECTION OF AUTOIMMUNE HEPATITIS SPECIFIC ANTI-SMOOTH MUSCLE ANTIBODIES DP Bogdanos, L Komorowski, C Liaskos, ET Davies, G Mieli-Vergani, ... Journal of Hepatology 46, S253-S254, 2007

1 2007

[25] IDENTIFICATION OF HLA-DR3 RESTRICTED CD4 T-CELL EPITOPES ON SOLUBLE LIVER ANTIGEN IN AUTOIMMUNE HEPATITIS TYPE 1

1 2007

D-P Bogdanos, CV

58

F Meda, P Wang, MS Longhi, DP Bogdanos, G Mieli-Vergani, D Vergani, ... Journal of Hepatology 46, S13, 2007

Anti-chromatin antibodies identify patients with overlap primary biliary cirrhosis/autoimmune hepatitis syndrome. S Leoni, Z Shuns, DP Bogdanos, HM Smith, MA Heneghan, GL Norman, ... Hepatology 40 (4), 461A-461A, 2004

1 2004

P0294 HLA DR7 POSITIVE PATIENTS WITH TYPE 2 AUTOIMMUNE HEPATITIS ARE CHARACTERISED BY A PROLONGED CLINICAL COURSE J Underhill, DP Bogdanos, MS Longhi, S Bansal, G Mieli-Vergani, ... Journal of Pediatric Gastroenterology and Nutrition 39, S169, 2004

1 2004

Anti-SLA antibodies preferentially recognise conformational epitopes in autoimmune liver disease Y Ma, DP Bogdanos, R Williams, G Mieli-Vergani, D Verganil Journal of Hepatology 34, 210, 2001

1 2001

Thyroid peroxidase is a molecular mimicry target of anti-hepatitis C virus humoral response DP Bogdanos, M Lenzi, M Okamoto, Y Ma, P Aluigi, F Lari, L Muratori, ... Journal of Hepatology 32, 103, 2000

1 2000

Treatment with interferon-alpha unmasks cross-reactive immunity between hepatitis C virus and thyroid peroxidase, the major target antigen in thyroid ayutoimmunity. DP Bogdanos, M Lenzi, Y Ma, PAF Lari, L Muratori, R Williams, ... Hepatology 30 (4), 363A-363A, 1999

1 1999

ENHANCED DETECTION AND CHARACTERIZATION OF PRIMARY BILIARY CIRRHOSIS PATIENTS WITH NEW M2 EP (MIT3), gp210, AND sp100 ELISA ASSAYS GL Norman, L Lee, Z Shums, DP Bogdanos, HJ Worman, EL Krawitt, ...

1

Bacterial Infections in Liver EI Rigopoulou, DS Smyk, T Orfanidou, DP Bogdanos, ME Gershwin Liver Immunology, 123-144, 2014

2014

Su1201 Diagnostic and Clinical Significance of the Pancreatic Autoantibodies Anti-GP2 and Anti-Cuzd1 in Inflammatory Bowel Diseases P Pavlidis, A Koutsoumpas, FA Sulttan, MG Mytilinaiou, A Forbes, ... Gastroenterology 5 (144), S-425-S-426, 2013

2013

Glycoprotein 2 Antibodies in Inflammatory Bowel Disease: No Association With Disease Phenotype? Response M Kovacs, G Veres JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 56 (1), E6-E6, 2013

2013

New sensitive technique for the detection of anti-smooth muscle antibodies in autoimmune hepatitis C Liaskos, MG Mytilinaiou, A Grammatikopoulos, DS Smyk, T Orfanidou, ...

2012

D-P Bogdanos, CV

59

HEPATOLOGY 56, 991A-992A, 2012