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CURRICULUM VITAE

Carol A. Bagnell, Ph.D

Department of Animal Sciences Ph: 848-932-6334; FAX: 732-932-6996

School of Environmental and Biological Sciences cbagnell@sebs.rutgers.edu

Rutgers - The State University of New Jersey http://animalsciences.rutgers.edu/faculty/bagnell

59 Dudley Road – Foran Hall Rm 126

New Brunswick, NJ 08901-8525

EDUCATION

Ph.D 1983 Endocrinology Medical College of Georgia, Augusta, GA

M.S. 1976 Biology West Virginia University, Morgantown, WV

B.A. 1974 Biology Glassboro State College, Glassboro, NJ

PROFESSIONAL EXPERIENCE

2014-present Director, Graduate Program in Endocrinology & Animal Biosciences,

Rutgers University, New Brunswick, NJ

2008-2014 Chair, Dept. of Animal Sciences, Rutgers University

2002- present Professor, Dept. of Animal Sciences, Rutgers University

1995 - 1999 Associate Chair, Dept. of Animal Sciences, Rutgers University

1994 - 2002 Associate Professor, Dept. of Animal Sciences, Rutgers University

1988 - 1989 Visiting Scientist in the laboratory of Dr. Kevin Catt, Endocrinology and

Reproduction Research Branch, NICHD, NIH, Bethesda, MD

1988 – 1994 Assistant Professor, Dept of Animal Sciences, Rutgers University

1987 -1988 Associate Researcher, Pacific Biomedical Research Center (PBRC)/Dept.

of Anatomy and Reproductive Biology, University of Hawaii, Honolulu.

1984 - 1987 Assistant Researcher, PBRC/Dept. of Anatomy and Reproductive

Biology, University of Hawaii; Acting Director, MARC Program

Spring 1983 Visiting Scientist, Institute of Histology and Embryology, University of

Geneva, Switzerland.

1983 - 1984 Postdoctoral Fellow, Dept. of Anatomy and Reproductive Biology and

Dept. of Biochemistry and Biophysics, University of Hawaii

RESEARCH INTERESTS

Studies in my laboratory focus on (1) improving our understanding of maternal programming of

development by testing the lactocrine hypothesis and (2) the role of the hormone relaxin in

reproduction. Our group defined the term ‘lactocrine’ as a means of maternal delivery of milk-borne

bioactive factors into the circulation of offspring as a consequence of nursing. Porcine milk contains

relaxin that is transmitted into the peripheral circulation of neonates only if they are allowed to nurse.

These studies indicate that a window of opportunity for transmission of milk-borne bioactive factors,

including relaxin, from mother to neonate is open during the first few days of life. Data from our

porcine model provide compelling evidence that maternal programming of neonatal female

reproductive tract development requires lactocrine signaling from birth. Current studies focus on the

short-term effects of milk-borne factors on neonatal development as well as the long-term

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consequences of lactocrine signaling on reproductive health and fertility in adulthood. Since all

mammals evolved to nurse, this research has broad implications for understanding maternal

contributions to postnatal reproductive tract programming in both humans and domestic animals.

GRANT SUPPORT- External

2016-2018 National Institute of Food and Agriculture/US Department of Agriculture:

“Maternal lactocrine programming of female reproductive tract development”,

Funding supplement $554,000, Co-PI with Frank Bartol; ($215,982 to Bagnell).

2013-2017 National Institute of Food and Agriculture/US Department of Agriculture:

“Maternal lactocrine programming of female reproductive tract development”,

$700,000 Co-PI with Frank Bartol; ($325,857 to Bagnell).

2007-2010 US Dept of Agriculture (USDA) Competitive Grants Program: “Molecular

markers and mediators of porcine reproductive tract development”, $343,912 Co-

PI with Frank Bartol, 3-yr renewal; ($152,009 to Bagnell).

2003-2007 USDA Competitive Grants Program: “Molecular markers and mediators of

porcine uterine development”, $297,869 Co-PI with Frank Bartol; ($169,139 to

Bagnell).

1999-2004 USDA Competitive Grants Program: “The role of relaxin in porcine uterine

growth and remodeling”, $180,000 PI.

1993-1997 USDA Competitive Grants Program: "Intraovarian role of relaxin in follicular

development", $239,000 PI.

1993-1995 Johnson & Johnson Discovery Award: "Cell adhesion molecules in the ovary:

Gene expression and immunolocalization", $20,000 PI.

1988-1991 NIH, FIRST Award 1 R29 HD 22885. Paracrine Control of Follicular Growth

and Ovulation", $157,500 PI.

1985-1988 NIH, New Investigator Research Award 1 R23 HD 20624. "Paracrine Control of

Follicular Growth and Ovulation", $107,500 PI.

1984-1985 NIH, NIGMS, MARC program subproject "Production and biological action of

relaxin in the ovarian follicle", $10,434 PI.

GRANT SUPPORT – Internal

USDA/NIFA – Cooperative State Research Service - Hatch Funding

2016-2021 “Role of milk-borne factors in neonatal reproductive tract development”. Project #

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NJ 06175; $10,000.

2010-2015 “Role of milk-borne factors in neonatal reproductive tract development”. Project #

NJ 06153; $10,000.

2004-2009 “Relaxin and estrogen interaction in porcine cervical development”. $10,000.

2003-2008 “Relaxin and estrogen interaction in porcine cervical development”. $10,000.

1997-2002 “The role of relaxin in control of porcine ovarian development. $10,000.

1993-1996 “Mechanism and nature of the relaxin receptor in the porcine follicle”. $10,000.

1988-1992 “Mechanism and nature of the relaxin receptor in the porcine follicle”. $10,000.

NJ Agriculture Experiment Station - Equine Initiative Funding

2007-2008 “Effects of nutritional supplements on exercise-induced inflammation and

oxidative stress in horses”, Co-PI with C Williams, $33,419

2006-2007 “Development of an exercise-induced joint inflammation model in horses”, Co-PI

with C Williams, $21, 590

2005-2006 “Joint inflammation in horses and cytokine assay development”, Co-PI with C

Williams, $35,000

2004-2005 “Inflammation in horses and cytokine assay development”, Co-PI with K

McKeever, C Williams, P Ryan, $44,000

2002-2004 “Equine relaxin and receptors: Markers of placental function”,

Total (2 awards): $81,000

1995-2002 "Equine relaxin as a diagnostic tool for assessing placental insufficiency and fetal

well-being in the mare", Total (5 awards): $164,834

Other Internal Funding

2004-2006 Busch Biomedical Research Grant: “Tumor suppressor role of epithelial cadherin

in human ovarian cancer”, $25,000

1990-1995 Biomedical Research Support Awards (4), Total: $25,516

1989-1991 Rutgers University Research Council Awards (3), Total: $6,800

RESEARCH SUPPORT - Other

2006-2021 Bernard and Jane Steinetz Research Fund, supported by the Steinetz Charitable

Lead Unitrust for 15 years starting in 2006; ~$65,000/yr; total income to date:

$832,117

2004 Lindstrom Foundation – gift in support of research, $6,000

2003 Novartis, Inc., East Hanover, NJ. Donation of laboratory equipment, estimated

value $45,000

2001-pres Carl N. Steinetz Memorial Fund. Endowment in support of research, ongoing

$111,591

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TRAINEE SUPPORT – Undergraduate Research

Aresty Undergraduate Research Awards:

2016 Julie Wang: Long term effects of nursing from birth on uterine protein during

pregnancy in the pig; Aresty Research Assistant support

2013 Jessica Lovich: Effects of age and nursing on RXFP1in the neonatal porcine heart;

$1000

2010 Lauren Barron: Influence of nursing on estrogen receptor-alpha and apoptotic-

related proteins in the porcine small intestine; $1000

2010 Kristene Welch: Uterine developmental programming and the impact of lactocrine

signaling; $1000

2009 Nathalie Sanchez: Effects of milk-borne factors on neonatal porcine cardiac

development; $1000

2008 Michael Strug: Role of estrogen and relaxin receptors in increasing mouse

interpubic ligament sensitivity to relaxin; $1000

2007 Megan Dilts: The role of relaxin on connective tissue remodeling and apoptosis in

the neonatal porcine heart and cervix; $1000

Undergraduate Research Fellowships sponsored:

1996- 2001 NJ Commission on Cancer Research Summer Fellowships

1996 "Cell adhesion molecules in cancer cells", $2,800.

1997 "Hormonal control of protease activity in ovarian cancer cells", $2,800.

1999 “Control of MMP activity in NIH-OVCAR ovarian cancer cells”, $2,800

2000 “Mechanism of growth factor action in human ovarian cancer”, $2,800

2001 "Estrogen receptor in growth factor action in ovarian cancer", $2,800

1997-2005 Rutgers University Undergraduate Fellowships (5) Total: $7,500

HONORS/PROFESSIONAL ACTIVITIES

2011 Relaxin 2012 – The 6th International Conference on Relaxin and Relaxin-Related

Peptides, Florence, Italy, Organizing Committee Member

2005 Relaxin 2008 – The 5th International Conference on Relaxin and Relaxin-Related

Peptides, Maui, Hawaii, Organizing Committee Member

2004 Graduate Program Service Award, Department of Animal Sciences, Rutgers

University, New Brunswick, NJ

2003 Distinguished Alumnus Award, Medical College of Georgia School of Graduate

Studies, Augusta, GA

Fall 2001 Sabbatical - Merck Research Laboratories, Rahway, NJ

& 2002 Division of Atherosclerosis and Endocrinology

2000 Relaxin 2004 - The 4th International Conference on Relaxin and Relaxin-Related

Peptides, Organizing Committee Member

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2002- pres Editorial Board, Reproductive Biology and Endocrinology

2002-2005 Editorial Board, Domestic Animal Endocrinology

1999-2003 Editorial Board, Biology of Reproduction

1996-1997 Sixth Annual ESCOP/ACOP Leadership Development Program, participant

1990-present Reviewer of USDA, NSF, NATO and BARD proposals

1988-present Reviewer, manuscripts submitted to American Journal of Physiology,

Endocrinology, Endocrine Journal and Journal of Endocrinology

PROFESSIONAL SOCIETY MEMBERSHIPS

American Assn for the Advancement of Science

Endocrine Society Society for the Study of Reproduction

Sigma Xi Women in Endocrinology

TEACHING EXPERIENCE

Current Teaching

Animal Reproduction (11:067:327; 3 credits; undergraduate)

Fall semesters 1997 – present (20 yrs); Course Coordinator

125-140 students/year

Animal Microtechniques and Tissue Culture (11:067:067:430; 4 credits; undergraduate)

Spring semesters 1989-present (28 yrs); 30-48 students/year

Upper-level laboratory course team-taught with Drs. Jesse and Uzumcu for students majoring

in Animal Sciences, Biotechnology or Biology

Physiology of Reproduction (16:067:502/16:340:502; 3 credits; graduate)

Course coordinator, 1999; Team-taught course every other year 1991 – 2013

Past Teaching – Undergraduate

Preveterinary Clinical Anatomy (11:067:380; 3 credits) 1989-1996 (7 yrs)

Preveterinary Clinical Anatomy Laboratory (11:067:381; 2 credits)

1989-1996; Upper-level courses intended for preveterinary students; 24 students/year

Animal Science (11:067:142; 3 credits)

1991-1996; First-year, introductory course team-taught with 4 other faculty members;

110 students

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Animal Nutrition (11:067:330; 3 credits)

Presented one lecture on nutrition and reproduction in 1991 and 1992

Past Teaching – Graduate

Current Principles of Animal Science (16:067:501; 3 credits; 1993)

Recent Advances in Animal Reproduction (16:067:612, 3 credits)

Team-taught with two other faculty, 1994

Graduate Seminar in Animal Sciences (16:067:693; 1 credit) Coordinator, 1993 and 2003

Teaching Grants

1998-1999 Rutgers University Grant. "Conversion of the Biotech Center Storage Room to a

Student Computing Facility for the Biotechnology and Animal Science Curricula

and Library Instruction", $40,000; (Co-PI with Zylstra and Gardner)

1996-1997 Instructional Computing Award Provost's Office. "Animal Science Departmental

Instructional Computing Proposal", $17,578 (C Bagnell, PI; B Jesse, Co-PI).

Funding of a student computing facility in Bartlett Hall.

1995-1996 Teaching Excellence Center Grant, "Production of Instructional Videos for

Veterinary Anatomy", $3,500 (C. Bagnell, PI)

INVITED SEMINAR PRESENTATIONS

A. Keynote or Plenary Addresses

1. 2017: “Lactocrine signaling and developmental programming” - Plenary Lecture. 10th

International Conference on Pig Reproduction, Columbia, MI, June 14, 2017

2. 2014: “Maternal programming of reproductive tract development: The lactocrine

hypothesis” Keynote Lecture. Dept of Physiology & Center for Reproductive Biology

and Health Retreat, Pennsylvania State University, State College, PA, November 7-8,

2014

3. 2012: “Maternal programming of neonatal development”, Russell Nutrition Symposium,

Rutgers University, New Brunswick, NJ, Nov 13, 2012

4. 2012: “Milk-borne relaxin and reproductive system development”, Relaxin 2012- the 6th

International Conference on Relaxin and Related Peptides, Florence, Italy, Oct 7-12, 2012

5. 2012: “Anti-arthritic actions of relaxin, in combination with estrogens, in joint and bone

tissues”, Relaxin 2012- the 6th International Conference on Relaxin and Related Peptides,

Florence, Italy, Oct 7-12, 2012

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6. 2008: “Milk-borne relaxin and the lactocrine hypothesis for maternal programming of

neonatal tissues”, Relaxin 2008- the 5th International Conference on Relaxin and Related

Peptides, Maui, HI, May 19-23, 2008

7. 2004: “Relaxin and neonatal porcine uterine growth and development”, Relaxin 2004 –

the Fourth International Conference on Relaxin and Related Peptides, Jackson Hole, WY,

September 5-10, 2004

8. 2004: “Relaxin and regulation of porcine uterine development and function”, Plenary

talk, Gordon Research Conference Reproductive Tract Biology, New London, CT

9. 2000: “Relaxin and uterine growth and remodeling”. Relaxin 2000, The 3rd International

Conference on Relaxin and Related Peptides, Broome, Australia

10. 1999: "Relaxin as a biochemical marker of placental insufficiency in the horse".

International Conference on Equine Reproductive Medicine, Celle, Germany

11. 1994: "Porcine relaxin: Gene expression during the cycle and pregnancy". Second

International Congress on the Hormone Relaxin, Adelaide, South Australia

12. 1993: "Sources and biological actions of relaxin in the pig". Plenary talk, 4th International

Conference on Pig Reproduction, Columbia, Missouri

13. 1986: "Paracrine control of follicle development". International Serono Symposium, Paris,

France

B. Other Invited Addresses

1. 2016: “Maternal lactocrine programming of reproductive tract development” Dept of Animal

Sciences, Cornell University, Ithaca, NY

2. 2016:“Role of Nursing from Birth on Reproductive Tract Development”

President’s Research Symposium, Augusta University, Augusta, GA

3. 2013: “Maternal lactocrine programming of neonatal development”, Dept of Dairy Science,

Virginia Polytechnic and State University, Blacksburg, VA, May 7, 2013

4. 2011: “Maternal lactocrine programming of reproductive tract development”, Neonatology

Group, Robert Wood Johnson Medical School, New Brunswick, NJ, November 18, 2011

5. 2009: “Maternal lactocrine programming of reproductive tract development”, Reproductive

Biology Symposium, West Virginia University, Morgantown, WV, July 17, 2009

6. 2008: “Molecular markers and mediators of porcine reproductive tract development: Year 1,

CSREES, USDA National Research Initiative Animal Reproduction Annual Investigator

Meeting. Indianapolis, IN, July 10, 2008

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7. 2006: “Mechanism of relaxin action in reproduction and beyond”, Department of Animal

Sciences, Rutgers University, New Brunswick, NJ, February, 24, 2006

8. 2004: “Equine relaxin: An insurance policy for pregnant mares”, New York University School

of Medicine, Institute of Environmental Medicine, Tuxedo, NY

9. 2004 “Equine relaxin: An insurance policy for pregnant mares”, 2004 New Jersey State

Agricultural Convention, Long Branch, NJ

10. 2003: “Equine relaxin: An insurance policy for pregnant mares”, Equine Research Update,

Rutgers University, New Brunswick, NJ

11. 2003: “A career in endocrinology: From PhD to Professor”, Medical College of GA,

Augusta, GA

12. 2003: “Relaxin: Mechanism of action and marker of placental function”, Cornell University

Ithaca, NY

13. 2002: "Ovarian gene array studies", Division of Endocrinology and Atherosclerosis, Merck

Research Laboratories, Rahway, NJ

14. 2001: "Relaxin and uterine growth and remodeling", Wyeth Ayerst, Women's Health

Research Institute, Radnor, PA

15. 2001: "Equine relaxin: A diagnostic marker of placental insufficiency" Endocrine Research

Interest Group, Rutgers University/UMDNJ, New Brunswick, NJ

16. 2001: "Relaxin and uterine growth and remodeling", Endocrinology Discovery Group, Merck

Research Laboratories, Rahway, NJ

17. 2001: "Equine relaxin: A tool to diagnose placental insufficiency and monitor fetal well-

being" Dept of Animal Sciences, Rutgers University, New Jersey

18. 2001: “Mechanism of relaxin action in uterine growth & remodeling" Dept. of Animal &

Dairy Science, Mississippi State University, Mississippi

19. 2000: “Mechanism of relaxin action in promoting uterine and cervical growth”. Dept of

Genetics and Molecular Biology, JA Burns School of Medicine, University of Hawaii, HI

20. 1999: "Equine relaxin as a diagnostic tool for placental insufficiency". Danish Veterinary

College, Royal Agricultural and Veterinary University of Copenhagen, Denmark

21. 1999: “Equine relaxin: A tool to diagnose placental insufficiency and monitor treatment

efficacy”. MacDonald College, McGill University, Montreal, Canada

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22. 1998:“The role of relaxin in reproductive tissue growth”. Dept. of Physiology, University of

Maryland Medical School, Baltimore, MD

23. 1998: “Equine relaxin - Diagnostic marker of placental insufficiency”. Havermeyer

Foundation Workshop on Equine Placentitis, Lexington, KY

24. 1998: “Trophic effects of relaxin: A role for the IGF system”. Symposium on Reproductive

Biology and Hormone Action, Augusta, GA

25. 1998: "Relaxin: Secretion and effects on the IGF system". Dept. of Biomedical Sciences,

University of Guelph, Ontario Canada

26. 1994: "Relaxin in the developing ovarian follicle". Dept. of Biology, Queens College, Flushing,

NY

27. 1993: "The role of relaxin in growth and remodeling of the ovary". Dept. of Obstetrics and

Gynecology, Loeb Medical Research Center, Ottawa, Ontario

28. 1991: "Paracrine control of the ovary: A role for relaxin". Department of Physiology, Cornell

University, Ithaca, NY

29. 1991: "In situ evidence for differential expression of relaxin mRNA by porcine theca

and granulosa lutein cells", Ottawa Civic Hospital, Ottawa, Ontario

30. 1990: "Ovarian relaxin gene expression". Department of Endocrinology and Physiology, Medical

College of Georgia, Augusta, Georgia

31. 1988: "Development of the corpus luteum - Local Control Factors". Department of Anatomy,

Howard University, Washington, D.C.

32. 1985: "A paracrine role for relaxin in ovulation and at parturition". Department of

Obstetrics and Gynecology, School of Medicine, University of Ottawa

GENBANK SUBMISSIONS

Bartol FF, Wiley A, Bathgate RAD, Bagnell CA. Sus scrofa neonatal uterus cDNA clone

pLGR7s similar to porcine LGR7 (Relaxin receptor). Accession number: CA994861; Short

(284bp) porcine relaxin receptor cDNA; Jan 7, 2003.

Bartol FF, Wiley A, Bathgate RAD, Bagnell CA. Sus scrofa neonatal uterus cDNA clone

pLGR7l similar to porcine LGR7 (Relaxin receptor). Accession number: CA994862; Long

(431bp) porcine relaxin receptor cDNA; Jan 7, 2003.

Bartol FF, Wiley A, Bathgate RAD, Bagnell CA. Sus scrofa neonatal uterus cDNA clone pLGR8

similar to porcine LGR8 (INSL3 receptor). Accession number: CA997681; Porcine INSL3

(198bp) receptor cDNA; Jan 8, 2003.

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PUBLICATIONS IN JOURNALS

Refereed, Research Journal Articles

1. George AF, Rahman KM, Camp ME, Prasad N, Bartol FF, Bagnell CA. 2017. Defining

age- and lactocrine-sensitive elements of the neonatal porcine uterine microRNA-mRNA

interactome. Biol Reprod 96(2): 327-340.

2. Ho TY, Rahman KF, Camp ME, Wiley AA, Bartol FF, Bagnell CA. 2016. Timing and

duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9

and tissue inhibitor of metalloproteinase 1. Domestic Animal Endocrinology 59: 1-10.

3. Rahman KM, Camp ME, Prasad N, McNeel AK, Levy SE, Bartol FF, Bagnell CA. 2016.

Age and nursing affect the neonatal porcine uterine transcriptome. Biol Reprod 94(2):46,

1-13.

4. Harvey C, Chen J, Bagnell CA, Uzumcu M. 2015. Methoxychlor and its metabolite

HPTE inhibit cAMP production and expression of estrogen receptors alpha and beta in rat

granulosa cells in vitro. Reproductive Toxicology 51:72-78.

5. Camp ME, Wiley AA, Boulos MB, Rahman KM, Bartol FF, Bagnell CA. 2014. Effects

of age, nursing, and oral IGF1 supplementation on neonatal porcine cervical

development. Reproduction 148: 441-451

6. Rahman KM, Lovich JE, Lam C, Camp ME, Wiley AA, Bartol FF, Bagnell CA. 2014.

Nursing supports neonatal porcine testicular development. Domestic Animal

Endocrinology 48: 84-92.

7. Miller DJ, Wiley AA, Chen JC, Bagnell CA, Bartol FF. 2013. Nursing for 48 h from

birth supports uterine gland development and endometrial cell compartment-specific gene

expression. Biol Reprod 88 (1):4, 1-10.

8. Frankshun A-L, Chen JC, Barron L, Ho T-Y, Miller DJ, Rahman K, Bartol FF, Bagnell

CA. 2012. Nursing during the first two days of life is essential for the expression of

proteins important for growth and remodeling of the neonatal porcine cervix.

Endocrinology 153(9):4511-4521.

9. Chen JC, Frankshun A-L, Wiley AA, Miller DJ, Welch KA, Ho T-Y, Bartol FF, Bagnell

CA. 2011. Relaxin and milk-borne lactocrine-acting factors affect morphoregulatory

gene and protein expression patterns in the neonatal porcine uterus. Reproduction

141:675-683.

10. Ho T-Y, Santora K, Frankshun A-L, Bagnell CA. 2011. Effects of relaxin and estrogens

on bone remodeling markers, receptor activator of NF-kB ligand (RANKL) and

osteoprotegerin (OPG), in rat adjuvant-induced arthritis. Bone 48:1346-1353.

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11. Frankshun A-L, Ho T-Y, Reimer DC, Chen J, Lasano S, Steinetz BG, Bartol FF, Bagnell

CA. 2011. Characterization and biological activity of relaxin in porcine milk.

Reproduction 141: 373-380.

12. Chen JC, Wiley AA, Ho T-Y, Frankshun A-L, Hord KM, Bartol FF, Bagnell CA. 2010.

Transient estrogen exposure from birth affects uterine expression of developmental

markers in neonatal gilts with lasting consequences in pregnant adults. Reproduction

139:623-630.

13. Lamprecht ED, Bagnell CA, Williams CA. 2009. Inflammatory responses to three

modes of intense exercise in Standardbred mares – a pilot study. Comparative Exercise

Physiology 5: 115-125.

14. Yan W, Chen J, Wiley AA, Bartol FF, Bagnell CA. 2008. Relaxin and estrogen affect

estrogen receptor , vascular endothelial growth factor and relaxin receptor expression in

the neonatal porcine uterus and cervix. Reproduction 135:705-712.

15. Santora K, Rasa C, Visco D, Steinetz BG, Bagnell CA. 2007. Antiarthritic effects of

relaxin, in combination with estrogen, in rat adjuvant-induced arthritis. Journal of

Physiology and Experimental Therapeutics 322(2): 887-893.

16. Ho TY, Yan W, Bagnell CA. 2007. Relaxin-induced matrix metalloproteinase-9

expression is associated with the activation of the NF-kB pathway in human THP-1 cells.

Journal of Leukocyte Biology 81:1303-1310.

17. Masters RA, Crean BD, Yan W, Moss A, Ryan PL, Wiley AA, Bagnell CA, Bartol FF.

2007. Neonatal porcine endometrial development and epithelial proliferation affected by

age and exposure to estrogen and relaxin. Domestic Anim Endocrinol 33: 335-346.

18. Yan W, Wiley AA, Bathgate RAD, Frankshun AL, Lasano S, Crean BD, Steinetz BG,

Bagnell CA, Bartol FF. 2006. Expression of LGR7 and LGR8 by neonatal porcine

uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by

suckling. Endocrinology 147:4303-10.

19. Yan W, Ryan PL, Bartol FF, Bagnell CA. 2006. Uterotrophic effects of relaxin related

to age and estrogen receptor activation in neonatal pigs. Reproduction 131:943-950.

20. Neumann J, Lazaris A, Huang YJ, Karatzas C, Ryan PL, Bagnell CA. 2006. Production

and characterization of recombinant equine prorelaxin. Domestic Animal Endocrinology

31:173-185.

21. Lenhart JA, Ryan PL, Ohleth KM, Palmer SS, Bagnell CA. 2002. Relaxin increases

secretion of tissue inhibitor of matrix metalloproteinase-2 and -9 during uterine and

cervical growth and remodeling in the pig. Endocrinology 143:91-98.

22. Ryan PL, Baum DL, Lenhart JA, Ohleth KM, Bagnell CA. 2001. Expression of uterine

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and cervical epithelial cadherin during relaxin-induced growth in pigs. Reproduction

122:929-937.

23. Lenhart JA, Ryan PL, Ohleth KM, Palmer SS, Bagnell CA. 2001. Relaxin increases

secretion of matrix metalloproteinase-2 and –9 during uterine and cervical growth and

remodeling in the pig. Endocrinology 142:3941-3949.

24. Ryan PL, Bennett-Wimbush K, Vaala WE, Bagnell CA. 2001. Systemic relaxin in

pregnant pony mares grazed on endophyte infected fescue: Effects of fluphenazine

treatment. Theriogenology 56:471-483.

25. Kirkup K, Mallin A, Bagnell CA. 2000. Inhibition of pig granulosa cell adhesion and

growth in vitro by immunoneutralization of epithelial cadherin. J Reprod & Fertility

120:275-281.

26. Lenhart JA, Ryan PL, Ohleth KM, Bagnell CA. 1999. Expression of connexin-26,-32

and -43 gap junction proteins in the porcine cervix and uterus during pregnancy and

relaxin-induced growth. Biol Reprod 61:1452-1459.

27. Ohleth KM, Zhang Q, Lenhart JA, Ryan PL, Bagnell CA. 1999. Trophic effects of

relaxin on reproductive tissue: Role of the IGF system. Steroids 64: 634-639.

28. Ohleth KM and Bagnell CA. 1999. Relaxin secretion and gene expression in porcine

granulosa and theca cells are stimulated during in vitro luteinization. Biol Reprod

60:499-507.

29. Wang-Lee JL, Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. 1998. Regulation of

urokinase- and tissue-type plasminogen activator by relaxin in the uterus and cervix of the

prepubertal gilt. J Reprod Fertility 114: 119-125.

30. Ohleth KM, Zhang Q, Bagnell CA. 1998. Relaxin protein and gene expression in

ovarian follicles of immature pigs. J Molecular Endocrinology 21:179-187.

31. Lenhart JA, Downey BR, Bagnell CA. 1998. Connexin 43 gap junction protein

expression during follicular development in the porcine ovary. Biol Reprod 58:583-590.

32. Ohleth KM, Lenhart JA, Ryan PL, Radecki SV, Bagnell CA. 1997. Relaxin increases

insulin-like growth factors and IGF binding proteins of the pig uterus in vivo.

Endocrinology 138:3652-3658.

33. Ryan PL, Valentine AF, Bagnell CA. 1996. Expression of E-cadherin in the developing

and adult pig ovary. Biol Reprod 55:1091-1097.

34. Ohleth KM and Bagnell CA. 1995. Relaxin-induced deoxyribonucleic acid synthesis in

porcine granulosa cells is mediated by insulin-like growth factor I. Biol Reprod 53:1286-

1292.

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35. Zhang Q and Bagnell CA. 1994. Trophic action of relaxin on porcine theca cells:

Interaction with insulin and IGF-I in vitro. Endocrine Journal 2:349-55.

36. Bagnell CA, Zhang Q, Ohleth K, Connor ML, Downey BR, Tsang BK, Ainsworth L.

1993. Developmental expression of the relaxin gene in the porcine corpus luteum. J

Molec Endocrinol 10:87-97.

37. Zhang Q and Bagnell CA. 1993. Relaxin stimulation of porcine granulosa cell

deoxyribonucleic acid synthesis in vitro: Interactions with insulin and insulin-like growth

factor I. Endocrinology 132:1643-1650.

38. Bagnell CA, Tashima L, Tsark W, Ali SM, McMurtry JP. 1990. Relaxin gene

expression in the sow corpus luteum during the cycle, pregnancy and lactation.

Endocrinology 126:2514-2520.

39. Bagnell CA, Tsark W, Tashima L, Downey BR, Tsang BK, Ainsworth L. 1990. Relaxin

gene expression in the porcine follicle during preovulatory development induced by

gonadotrophins. Molecular Endocrinology 5:211-219.

40. Bagnell CA, Baker NK, McMurtry JP, Brocht DM, Lewis GS. 1990. Control of luteal

relaxin release by prostaglandin F2α: Differences in the sow cycle and pregnancy.

Proceedings of the Society for Experimental Biology and Medicine 194:125-130.

41. Bagnell CA, Ayau E, Downey BR, Tsang BK, Ainsworth L. 1989. Localization of

relaxin during formation of the corpus luteum. Biol Reprod 40:835-41.

42. Bagnell CA, Baker NK, McMurtry JP. 1989. Immunohistochemical localization of

insulin in the chick embryo during development. General and Comparative

Endocrinology 73:293-298.

43. Bagnell CA, Frando LB, Downey BR, Tsang BK, Ainsworth L. 1987. Localization of

relaxin in the pig follicle during preovulatory development. Biol Reprod 37:235-40.

44. Bagnell CA, McMurtry JP, Baker NK, Timtim JL, Bryant-Greenwood GD. 1987.

Detection of relaxin by immunohistochemistry in the corpus luteum during lactation.

Biol Reprod 37:1317-1325.

45. Ali SM, McMurtry JP, Bagnell CA, Bryant-Greenwood GD. 1986.

Immunocytochemical localization of relaxin in corpora lutea of sows throughout the

estrous cycle. Biol Reprod 34:139-43.

46. Koay ESC, Bagnell CA, Bryant-Greenwood GD, Lord SB, D'Cruz A, Larkin LH. 1985.

Immunocytochemical localization of relaxin in human decidua and placenta. J Clin Endo

Metab 60:859-63.

47. Bagnell CA, Mills T, Costoff A, Mahesh VB. 1982. A model for the study of androgen

effects on follicular atresia and ovulation. Biol Reprod 27:903-14.

14

Refereed Journal Articles – Reviews

48. Bagnell CA, Ho TY, George AF, Wiley AA, Miller DJ, Bartol FF. 2017. Maternal lactocrine

programming of porcine reproductive tract development. Molec Reprod and Development,

doi: 10.1002/mrd.22815.

49. Bartol FF, Wiley AA, George AF, Miller DJ, Bagnell CA. 2017. Postnatal reproductive

development and the lactocrine hypothesis. J Anim Science 95(5): 2200-2210.

50. Bartol FF, Wiley AA, Miller DJ, Silva AJ, Roberts KE, Davolt MLP, Chen JC,

Frankshun A-L, Camp ME, Rahman KM, Vallet JL, Bagnell CA. 2013. Lactation

Biology Symposium: Lactocrine signaling and developmental programming. Journal of

Animal Science 91:696-705.

51. Bartol FF and Bagnell CA. 2012. Lactocrine programming of female reproductive tract

development: Environmental connections to the reproductive continuum. Mol Cell

Endocrinol 354:16-21.

52. Bagnell CA, Steinetz BG, Bartol FF. 2009. Milk-borne relaxin and the lactocrine

hypothesis for maternal programming of neonatal tissues. Ann N Y Acad Sci 1160:152-

157.

53. Bartol FF, Wiley AA, Bagnell CA. 2009. Relaxin and maternal lactocrine programming

of neonatal uterine development. Ann N Y Acad Sci 1160:158-163.

54. Chen J, Wiley AA, Kauffold H, Wahner M, Bartol FF, Bagnell CA. 2009. Perinatal

zearalenone exposure affects RXFP1, RXFP2 and morphoregulatory gene expression in

the neonatal porcine uterus. Ann N Y Acad Sci 1160: 188-189.

55. Frankshun AL, Ho TY, Steinetz BG, Bartol FF, Bagnell CA. 2009. Biological activity

of relaxin in porcine milk. Ann N Y Acad Sci 1160:164-168.

56. Ho TY, Dilts MA, Bartol FF, Bagnell CA. 2009. Relaxin promotes matrix

metalloproteinase-2 and decreases Wnt/-catenin expression in the neonatal porcine

heart. Ann N Y Acad Sci 1160:287-288.

57. Ryan PL, Christiansen DL, Hopper RM, Bagnell CA, Vaala WE, LeBlanc MM. 2009.

evaluation of systemic relaxin blood profiles in horses as a means of assessing placental

function in high-risk pregnancies and responsiveness to therapeutic strategies. Ann NY

Acad Sci 1160: 169-178.

58. Wiley AA, Kauffold J, Wähner M, Crean-Harris B, Miller D, Bagnell CA, Bartol FF.

2009. Laser microdissection of neonatal porcine endometrium for tissue specific

evaluation of relaxin receptor (RXFP1) expression in response to perinatal zearalenone

exposure. Ann N Y Acad Sci 1160:190-191.

59. Yan W, Wiley, AA, Bartol FF and Bagnell CA. 2005. Tissue-specific effects of relaxin

15

on the reproductive tract of neonatal gilts. Ann N Y Acad Sci. 1041:132-5.

60. Bagnell CA, Yan W, Wiley AA, Bartol FF. 2005. Effects of relaxin on neonatal porcine

uterine growth and development. Ann N Y Acad Sci. 1041:248-55.

61. Ho TY and Bagnell CA. 2005. Relaxin induces matrix metalloproteinase-9 through

activation of nuclear factor kappa B in human THP-1 cells. Ann N Y Acad Sci.

1041:314-6.

62. Santora K, Rasa C, Ronan J, Visco D, Steinetz B, Bagnell CA. 2005. Effects of relaxin in

a model of rat adjuvant-induced arthritis. Ann N Y Acad Sci. 1041:481-5.

63. Ryan PL, Bennet-Wimbush K, Vaala W, Bagnell CA. 1999. Relaxin as a biochemical

marker of placental insufficiency in the horse: a review. Pferdeheilkunde (Equine Health)

15: 622-626.

64. Bagnell CA, Zhang Q, Downey BR, Ainsworth L. 1993. Sources and biological actions

of relaxin in the pig. J Reprod Fert Suppl 48:127-138.

65. Bagnell CA. 1991. Production and biologic action of relaxin within the ovarian follicle:

An Overview. Steroids 56:242-246.

66. Mahesh VB, Mills TM, Bagnell CA, Conway BA. 1987. Animal models for study of

polycystic ovaries and ovarian atresia. Advances in Expt Medicine and Biology 219:

237-257.

67. Gambrell R, Bagnell CA, Greenblatt R. 1983. Role of estrogens and progesterone in the

etiology and prevention of endometrial cancer. Am J Obstet and Gynecol 146(6): 696-

707.

PUBLICATIONS IN BOOKS

1. Bartol FF, Wiley AA, Bagnell CA. 2008. Epigenetic programming of porcine

endometrial function and the lactocrine hypothesis. Reprod Dom Anim (July) 43(2): 281-

287.

2. Bartol FF, Wiley AA, Bagnell CA. 2006. Uterine development and endometrial

programming. Soc Reprod Fertil Suppl 62:113-130.

3. Lenhart J, Ohleth K, Ryan P , Wang-Lee J, Bagnell CA. 2001. Relaxin and porcine

uterine growth and remodeling. In: Relaxin 2000 edited by GW Tregear, R Ivell, RA

Bathgate and JD Wade, Kluwer Scientific Publishers, Netherlands, pp 83-89.

4. Ryan PL, Bennett-Wimbush K, Vaala WE, Bagnell CA. 2001. Relaxin and placental

dysfunction in the horse. In: Relaxin 2000 edited by GW Tregear, R Ivell, RA Bathgate

and JD Wade, Kluwer Scientific Publishers, Netherlands, pp. 91-99.

16

5. Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 1999. Effect of relaxin on

tissue inhibitor of metalloproteinase-1 and -2 in the porcine uterus and cervix. In: RA

Greenwald, S Zuker, LM Golub (eds). Inhibition of Matrix Metalloproteinases:

Therapeutic Applications, Annals of the NY Acad of Sciences Vol 878: 565-566.

6. Bagnell CA. 1995. Porcine relaxin: Gene expression during the cycle and pregnancy.

In: A MacLennan, G. Tregear G.D. Bryant-Greenwood (eds). Progress in Relaxin

Research. World Scientific Publishing Co., Singapore pp. 93-100.

7. Bagnell CA, Ohleth K, Clark CL, Taylor MJ. 1993. Detection of relaxin secretion and

gene expression in individual porcine luteal cells. In: P.C.K. Leung, A.J.W. Hsueh, and

H.G. Friesen (eds). Molecular Basis of Reproductive Endocrinology. Springer-Verlag,

NY, pp. 264-269.

8. Bagnell CA, Ainsworth L, Bryant-Greenwood GD, Greenwood FC. 1987. Follicular

relaxin: A role in the paracrine control of ovarian function. In: F. Naftolin, A.

DeCherney (eds). The Control of Follicle Development, Ovulation and Luteal Function:

Lessons from In Vitro Fertilization. Raven Press, NY, pp. 35-44.

9. Bagnell CA, McMurtry JP, Lewis GS. 1987. The effect of prostaglandin F on relaxin

release differs in the cyclic and pregnant sow. In: V.B. Mahesh, D.S. Dhinsa, E.

Anderson, S.P. Kalra (eds). Regulation of Ovarian and Testicular Function. Plenum

Press, NY, pp. 715-719.

10. Bagnell CA, Greenwood FC, Bryant-Greenwood GD. 1984. A paracrine role for

follicular relaxin. In: M.R. Sairam and L.E. Atkinson (eds). Gonadal Proteins and

Peptides and Their Biological Significance. World Scientific Publ. Co, Singapore, pp.

299-308.

11. Mahesh VB, Costoff A, Mills T, Bagnell CA. 1982. The polycystic ovary syndrome and

experimental models for the study of its pathogenesis. In: T. Muldoon, V. Mahesh, B.

Perez-Ballester (eds). Recent Advances in Fertility Research, Part A: Developments in

Reproductive Endocrinology. Alan R. Liss, NY, pp. 301.

PUBLICATIONS – in press/ in preparation

George AF and Bagnell CA. 2017. Relaxin. In: M Skinner (ed). Encyclopedia of Reproduction,

2nd Edition, Volume 2, Female Reproduction - Pregnancy, Chapter 91. Elsevier Inc., Waltham,

MA, in press.

George AF, Rahman KM, Miller DJ, Wiley AA, Camp M, Bartol FF, Bagnell CA. Effects of

colostrum, feeding method and oral IGF1 on porcine uterine development. In review in

Reproduction.

George AF, Prasad N, Keel B, Vallet JA, Bartol FF, Bagnell CA. Long-term effects of nursing

on the uterine porcine transcriptome at pregnancy day 13. In preparation.

17

George AF, Vallet JA, Bartol FF, Bagnell CA. Long-term effects of lactocrine deficiency on

proteomic analysis of porcine uterine secretions in early pregnancy. In preparation.

ABSTRACTS

Gray KK, Wiley AA, Miller DJ, Vallet JL, Bagnell CA, Bartol FF. 2017. Lactocrine-deficient

gilts exhibit altered patterns of endometrial development on postnatal day 14. 50th Meeting of

the Society for the Study of Reproduction, Washington, DC, July 2017.

George AF, Miller DJ, Wiley AA, Bartol FF, Bagnell CA. 2017. Nursing for 12 hours from

birth supports neonatal porcine uterine development. 50th Meeting of the Society for the Study of

Reproduction, Washington, DC, July 2017.

George AF, Rahman KM, Camp ME, Prasad N, Bartol FF, Bagnell CA. 2016. Integrated

microRNA-mRNA expression profiling by next generation sequencing reveals age- and

lactocrine-sensitive biological processes in the neonatal porcine uterus. 49th Meeting of the

Society for the Study of Reproduction, San Diego, CA, July 2016.

George AF, Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2015. Colostrum, oral

insulin-like growth factor-1, and pregnant sow serum support neonatal porcine uterine cell

proliferation. 48th Annual Meeting of the Society for the Study of Reproduction, San Juan, PR,

June 2015.

Selected for a 2015 USDA NRI AFRI Merit Award

Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2015. Defining the age-sensitive

neonatal porcine uterine transcriptome. 48th Annual Meeting of the Society for the Study of

Reproduction, San Juan, PR, June 2015.

Ho T, Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2015. Timing of colostrum

consumption and duration of nursing from birth affect neonatal porcine uterine and cervical

MMP9 and TIMP1 expression. 48th Annual Meeting of the Society for the Study of

Reproduction, San Juan, PR, June 2015.

Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2014. Colostrum and oral insulin-

like growth factor-1 support neonatal porcine cervical proliferation and development. 47th

Annual Meeting of the Society for the Study of Reproduction, Grand Rapids, MI, July 2014.

Rahman KM, Camp ME, Prasad N3, McNeel AK, Levy SK, Bartol FF, Bagnell CA. 2014.

Defining the lactocrine-sensitive neonatal porcine uterine transcriptome. 47th Annual Meeting of

the Society for the Study of Reproduction, Grand Rapids, MI, July 2014.

Camp ME, Boulos MB, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2013. Lactocrine

effects on porcine cervical histoarchitecture and cell proliferation. 46th Annual Meeting of the

Society for the Study of Reproduction, Palais de Congress, Montreal, Canada, July 22-26, 2013

18

Rahman KM, Lovich JE, Lam C, Camp ME, Bartol FF, Bagnell CA. 2013. Nursing supports

neonatal porcine testicular development: Lactocrine effects on Sertoli cell number and

proliferation. 46th Annual Meeting of the Society for the Study of Reproduction, Palais de

Congress, Montreal, Canada, July 22-26, 2013

Oral presentation selected for an SSR Agricultural Fellowship Award

Roberts KE, Davolt ML, Miller DJ, Wiley AA, Bagnell CA, Bartol FF. 2013. Identification of

cell compartment-specific gene expression events associated with estrogen receptor-alpha

dependent endometrial development using multispectral imaging and digital image processing.

46th Annual Meeting of the Society for the Study of Reproduction, Palais de Congress, Montreal,

Canada, July 22-26, 2013

Uczkowski HM, Camp ME, Rahman KM, Bartol FF, Bagnell CA. 2012. The effects of nursing

on expression of estrogen receptor alpha in the neonatal porcine brain. University of Sao Paulo,

Faculty of Food Engineering and Animal Science, 20th International Symposium of

Undergraduate Research, Sao Paulo, Brazil, Oct, 2012.

Uczkowski HM, Camp ME, Rahman KM, Bartol FF, Bagnell CA. 2012. Importance of nursing

for estrogen receptor-alpha expression in the neonatal porcine cerebral cortex and hypothalamus.

Annual Meeting of the Society for the Study of Reproduction, Penn State U, PA, August 12-15.

Rahman KM, Chen JC, Camp ME, Bartol FF, Bagnell CA. 2012. Nursing supports expression of

proteins associated with neonatal porcine testicular development. Annual Meeting of the Society

for the Study of Reproduction, Penn State U, PA, August 12-15.

Camp ME, Rahman KM, Bartol FF, Bagnell CA. 2012. A neonatal porcine bioassay for

identification of lactocrine activity in colostrum. Annual Meeting of the Society for the Study of

Reproduction, Penn State U, PA, August 12-15.

Camp ME, Ferio KM, Chen JC, Welch KM, Bartol FF, Bagnell CA. 2011. Defining a Critical

Time Period for Lactocrine Signaling in Support of Neonatal Porcine Cervical Development.

Annual Meeting of the Society for the Study of Reproduction, Portland, OR, July 31-August 4.

Ferio KM, Chen JC, Welch KA, Camp ME, Bartol FF, Bagnell CA. 2011. Age and Duration-

Dependent Effects of Lactocrine Signaling on Markers and Mediators of Uterine Growth and

Remodeling in Neonatal Gilts. Annual Meeting of the Society for the Study of Reproduction,

Portland, OR, July 31-August 4.

Miller DJ, Silva AJ, Wiley AA, Bagnell CA, Bartol FF. 2011. Nursing for 48 h from birth

supports normal Tissue compartment-specific gene expression events and neonatal porcine

endometrial morphogenesis. Annual Meeting of the Society for the Study of Reproduction,

Portland, OR, July 31-August 4.

Selected for a 2011 USDA NRI CSREES Merit Award

Bartol FF, Chen JC, Miller DJ, Frankshun A-L, Wiley AA, Silva AJ, Camp ME, Ferio KM,

Bagnell CA. 2011. The lactocrine hypothesis: Programming reproductive tract development.

Triennial Lactation Symposium (In honor of Dr. Alan Tucker) 2011 ADSA/ASAS Joint Annual

19

Meeting, July 10-14, New Orleans, LA.

Barron LA, Frankshun A-L, Bartol FF, Bagnell CA. 2011. Influence of nursing on estrogen

receptor α and apoptotic-related proteins in the porcine small intestine. SEBS Undergraduate

Research Symposium, Cook Campus, Rutgers University, April 2011.

First prize – 2011 SEBS Undergraduate Research Poster Competition

Bartol FF, Chen JC, Miller DJ, Frankshun A-L, Wiley AA, Silva AJ, Camp ME, Ferio KM,

Bagnell CA. 2011. The lactocrine hypothesis: Programming reproductive tract development. J

Anim Sci 89 (E-Suppl 1):1 (Abstract 3).

Bartol FF, Bagnell CA. 2010. Programming reproductive tract development. J. Anim. Sci. Vol.

88, E-Suppl. 2, P.793 (Abst 917)

Barron LA, Frankshun A-L, Bartol FF, Bagnell CA. 2010. Influence of nursing on markers of

apoptosis in the neonatal porcine small intestine. University of Sao Paulo, Faculty of Food

Engineering and Animal Science, 18th International Symposium of Undergraduate Research, Sao

Paulo, Brazil, Nov, 2010.

Welch KA, Chen J, Frankshun A-L, Bartol FF, Bagnell CA. 2010. The role of milk-borne

factors on matrix metalloproteinase (MMP) 9 protein and gene expression in the neonatal porcine

uterus. University of Sao Paulo, Faculty of Food Engineering and Animal Science, 18th

International Symposium of Undergraduate Research, Sao Paulo, Brazil, Nov, 2010.

Chen JC, Frankshun A-L, Welch KA, Ferio KM, Wiley AA, Ho T-Y, Bartol FF, Bagnell CA.

2010. Lactocrine signaling supports matrix metalloproteinase (MMP) 9 expression in the

neonatal porcine uterus. Annual Meeting of the Society for the Study of Reproduction,

Milwaukee, WI, July 30-August 3.

Selected for a 2010 USDA NRI CSREES Merit Award

Ferio KM, Frankshun A-L, Chen JC, Ho T-Y, Miller DJ, Bartol FF, Bagnell CA. 2010.

Colostrum is important for estrogen receptor- expression in male and female neonatal porcine

reproductive tissues. Annual Meeting of the Society for the Study of Reproduction, Milwaukee,

WI, July 30-August 3.

Frankshun A-L, Chen JC, Barron LA, Ferio KM, Miller DJ, Bartol FF, Bagnell CA. 2010.

Nursing during the first 48 h of life is important for expression of proteins involved in neonatal

porcine cervical development at postnatal day 14. Annual Meeting of the Society for the Study of

Reproduction, Milwaukee, WI, July 30-August 3.

Sanchez N, Chen JC, Miller DJ, Wiley AA, Bartol FF, Bagnell CA. 2010. Effects of lactocrine

signaling and relaxin on estrogen and relaxin receptor expression in the neonatal porcine heart.

Annual Meeting of the Society for the Study of Reproduction, Milwaukee, WI, July 30-August 3.

Silva AJ, Wiley AA, Frankshun A-L, Bagnell CA, Bartol FF. 2010. Defining the porcine milk

proteome. Annual Meeting of the Society for the Study of Reproduction, Milwaukee, WI, July

30-August 3.

20

Welch KA, Chen JC, Frankshun A-L, Bartol FF, Bagnell CA. 2010. The role of milk-borne

factors on matrix metalloproteinase (MMP) 9 expression in the neonatal porcine uterus. SEBS

Undergraduate Research Symposium, Cook Campus, Rutgers University, April 2010.

First prize – 2010 SEBS Undergraduate Research Poster Competition

Sanchez N, Chen JC, Miller DJ, Wiley AA, Bartol FF, Bagnell CA. 2009. The effects of milk-borne

factors on estrogen receptor expression in the neonatal porcine heart. University of Sao Paulo,

Faculty of Food Engineering and Animal Science, 17th International Symposium of Undergraduate

Research, Sao Paulo Brazil, Nov 3, 2009

Chen JC, Frankshun A-F, Wiley AA, Miller DJ, Welch KA, Ho T-Y, Bartol FF, Bagnell CA.

2009. Relaxin and milk-borne lactocrine-acting factors affect morphoregulatory gene expression

patterns in the neonatal porcine uterus. Annual Meeting of the Society for the Study of

Reproduction, Pittsburgh, Pennsylvania, July 18-21.

Frankshun A-L, Chen JC, Miller DJ, Wiley AA, Ho T-Y, Bartol FF, Bagnell CA. 2009. Milk

and relaxin affect expression of proteins important for growth, remodeling and apoptosis of the

neonatal porcine cervix. Annual Meeting of the Society for the Study of Reproduction,

Pittsburgh, Pennsylvania, July 18-21.

Strug M, Frankshun A-L, O’Byrne E, Lasano S, Steinetz BG, Bagnell CA. 2009. Development

of prepubertal mouse interpubic joint sensitivity to estrogen and relaxin. Annual Meeting of the

Society for the Study of Reproduction, Pittsburgh, Pennsylvania, July 18-21.

Strug M., Frankshun A.L., Lasano S., Steinetz B.G., Bagnell C.A. 2008. Role of estrogen and

relaxin receptors in increasing neonatal mouse interpubic ligament sensitivity to relaxin.

University of Sao Paulo, Faculty of Food Engineering and Animal Science, 16th International

Symposium of Undergraduate Research, Sao Paulo Brazil, Nov 3, 2008

Frankshun A, Steinetz B, Bartol FF, Bagnell CA. 2008. Characterization and biological activity of

milk-borne relaxin. Gordon Research Conference on Reproductive Tract Biology, Andover, NH,

Aug 3-8.

Chen J, Wiley AA, Kauffold H, Wahner M, Bartol FF, Bagnell CA. 2008. Perinatal

zearalenone exposure affects RXFP1, RXFP2 and morphoregulatory gene expression in the

neonatal porcine uterus. Gordon Research Conference on Reproductive Tract Biology, Andover,

NH, Aug 3-8.

Lamprecht, ED, Bagnell CA, Williams CA. 2008. Effect of exercise and superoxide dismutase

on systemic antioxidants and nitric oxide in horses. Am. Soc. Anim Sci Proc 86.

Naftolovich R, Ho TY, Frankshun AL, Chen J, Bagnell CA. 2007. In vitro effects of relaxin on

matrix metalloproteinase-2 expression and activity in the porcine neonatal heart. University of

Sao Paulo, Faculty of Food Engineering and Animal Science, 15th International Symposium of

Undergraduate Research, Sao Paulo, Brazil, Nov 28-29, 2007.

21

Chen J, Frankshun A, Ho T, Bartol FF, Bagnell CA. 2007 Estrogen exposure from birth affects

uterine gene expression in neonatal gilts that persists in pregnant adults. 40th Annual Meeting of

the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007.

Lamprecht ED, Bagnell CA, Williams CA. 2007. Inflammatory responses to three modes of

intense exercise in Standardbred mares. Equine Science Society Proceedings 20: 76-77.

Crean BD, Masters RA, Yan W, Wiley AA, Bagnell CA, Bartol FF. 2006 Porcine uterine

expression of MSX1 and MSX2: Effects of relaxin, estrogen and ICI 182,780 in the neonatal

endometrium. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NE,

July 27-Aug 1, 2006.

Ho T, Santora K, Yan W, Visco D, Bagnell CA. 2006 Relaxin and estrogen regulate the bone

remodeling markers, receptor activator of nuclear factor-kappa B ligand (RANKL) and

osteoprotegerin (OPG) in rat adjuvant-induced arthritis. 39th Annual Meeting of the Society for

the Study of Reproduction, Omaha, NE, July 27-Aug 1, 2006.

Ho T, Yan W, Wiley AA, Bartol FF, Bagnell CA. 2005 Evolution of the Hoxa/Wnt Axis and

estrogen regulation of Wnt7a expression in the neonatal porcine uterus. 38th Annual Meeting of

the Society for the Study of Reproduction, Quebec, Canada, July 24-27.

Santora K, O’Byrne E, Visco D, Steinetz BG, Bagnell CA. 2005. Relaxin decreases tumor

necrosis factor in chronic and acute rat models of joint inflammation. 38th Annual Meeting of

the Society for the Study of Reproduction, Quebec, Canada, July 24-27.

Yan W, Lasano S, Steinetz BG, Bartol FF, Bagnell CA. 2005. Presence of relaxin in the milk of

lactating sows and its transmission to neonatal pigs via suckling. 38th Annual Meeting of the

Society for the Study of Reproduction, Quebec, Canada, July 24-27.

Masters RA, Crean BD, Yan W, Wiley AA, Bagnell CA, Bartol FF. 2005. Distribution of active

beta-catenin in neonatal porcine uterine tissues affected by age and exposure to estrogen and relaxin.

38th Annual Meeting of the Society for the Study of Reproduction, Quebec, Canada, July 24-27.

Yan W, Wiley AA, Bartol FF, Bagnell CA. 2004. Tissue-specific response to relaxin in the

reproductive tract of neonatal gilts: LGR7 expression and regulation by relaxin. Relaxin 2004 –

the Fourth International Conference on Relaxin and Related Peptides, Jackson Hole, WY,

September 5-10, 2004.

Santora K, Rasa C, Ronan J, Visco D, Steinetz B, Bagnell CA. 2004. Effects of relaxin in a

model of rat adjuvant-induced arthritis. Relaxin 2004 – the Fourth International Conference on

Relaxin and Related Peptides, Jackson Hole, WY, September 5-10, 2004.

Ho TY, Bagnell CA. 2004. Relaxin induces matrix metalloproteinase-9 through activation of

nuclear factor kappa B in human THP-1 cells. Relaxin 2004 – the Fourth International

Conference on Relaxin and Related Peptides, Jackson Hole, WY, September 5-10, 2004.

22

Yan W, Wiley, AA, Bartol FF, Bagnell CA. 2004. Tissue-specific response to relaxin in the

reproductive tract of neonatal gilts: LGR7 expression and regulation by relaxin. Gordon

Research Conference – Reproductive Tract Biology, June 6-11, 2004, New London, CT.

Yan W, Bagnell CA. 2003. Effects of relaxin on estrogen receptor and vascular endothelial growth

factor expression in the cervix and vagina of neonatal pigs. Soc for Theriogenology, Sept 16 –20,

2003, Columbus, OH.

Wiley A, Bartol FF, Bathgate RA, Bagnell CA. 2003. Relaxin (LGR7) and insulin-like peptide-3

(LGR8) receptor expression in neonatal porcine uterine tissues. Biol Reprod 68(1): 156.

Yan W, Ryan PL, Bagnell CA. 2002. Tissue-specific effects of relaxin on the reproductive tract of

neonatal pigs: Estrogen receptor-dependent and independent actions. Biol Reprod 66(1): 202.

Neumann J, Liu SW, Bagnell CA. 2002. Relaxin increases vascular endothelial growth factor

production through a cAMP-dependent mechanism in the human monocyte cell line, THP-1.

Biol Reprod 66(1): 200.

Bagnell CA, Neumann J, Ryan PL. 2002. Equine relaxin: A diagnostic marker of placental

insufficiency and fetal well-being. Advances in Therapeutic Agents Discovery and

Development, January 29, Rutgers University, New Brunswick, NJ.

Neumann J, Huang Y-J, Ryan PL, Bagnell CA. 2001. Production and characterization of

recombinant equine relaxin. Biol Reprod 64(1): 599.

Malkiewicz S, Bagnell CA. 2001. Mechanism of growth factor action in an ovarian cancer cell

line. Rutgers Undergraduate Fellows Program, April 25, Rutgers University, New Brunswick,

NJ.

Neumann J, Huang Y-J, Bagnell CA. 2000. Strategies for the production of recombinant equine

relaxin. Equine Research Update, Dec 9, Rutgers University, New Brunswick, NJ.

Ryan P, Vaala W, Bagnell CA. 2000. Relaxin and placental dysfunction in the horse. Relaxin

2000 – 3rd International Meeting on relaxin and relaxin-like peptides. Oct 22-27, Broome,

Australia.

Lenhart JA, French KA, Bagnell CA. 2000. Effect of relaxin on vascular endothelial growth

factor in the porcine uterus and cervix. Biol Reprod 62 (1):492.

Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 2000. Matrix metalloproteinase-2 in

the porcine uterus and cervix: Effects of relaxin. 21st Century Workshop on Animal

Biotechnology, April 7, Rutgers University, New Brunswick, NJ.

Lenhart JA, Ryan PL, Ohleth KM, Bagnell CA. 1999. Differential expression of connexin-26, -

32 and -43 gap junction proteins in the porcine cervix during relaxin-induced growth and

remodeling. Biol Reprod 60 (1): 250.

23

Ryan P, Bennet-Wimbush K, Loch W, Vaala W, Bagnell CA. 1998. Effects of fescue toxicosis

and fluphenazine on relaxin concentrations in pregnant pony mares. American Association of

Equine Practitioners Proceedings 44: 60-61.

Ryan P, Vaala W, Bagnell CA. 1998. Evidence the equine relaxin in a good indicator of

placental insufficiency in the mare. AAEP Proceedings 44: 62-63.

Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 1998. Effect of relaxin on tissue

inhibitor of metalloproteinase (MMP)-1 and -2 in the porcine uterus and cervix. NY Academy of

Sciences Conference, Inhibition of MMPs: Therapeutic Applications, Tampa, FL.

McGonigle KM, Lenhart JA, McConochie RM, Bagnell CA. 1998. Effects of relaxin on the

porcine granulosa cell matrix metalloproteinase system. XII Ovarian Workshop, Houston, TX.

Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 1998. Effect of relaxin on matrix

metalloproteinase-2 in the porcine uterus and cervix. Biol Reprod 58 (1):326.

Kirkup KM and Bagnell CA. 1998. Immunoneutralization of epithelial cadherin inhibits

porcine granulosa cell DNA synthesis. Biol Reprod 58 (1):33.

Lenhart JA, McGonigle KM, Ohleth KM, Ryan PL, Bagnell CA.1997. Matrix metalloproteinase

activity is modulated by relaxin in porcine granulosa cells and the uterus. Biol Reprod 56(1):209.

Ohleth KM and Bagnell CA. 1997. Relaxin secretion from porcine theca and granulosa cells is

stimulated by in vitro luteinization. Biol Reprod 56(1):253.

Ryan PL, Vaala WE, Bagnell CA. 1997. Equine relaxin: Hormonal measurement of placental

insufficiency in the at-risk pregnant mare. Biol Reprod 56(1):437.

Ryan PL, Vaala WE, Bagnell CA. 1997. Equine relaxin: A diagnostic tool for assessing at risk

pregnancies and parturient complications in the mare. 15th Equine Nutrition and Physiology

Symposium, Fort Worth, Texas, May 29-31, 1997.

Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. 1996. Connexin 43 gap junction expression

increases in the porcine cervix and uterus during relaxin-induced growth and remodeling. Biol

Reprod 54(1):250.

Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. 1996. The effect of relaxin in vivo on porcine

ovarian follicular fluid proteoglycan levels and matrix metalloproteinases. XIth Ovarian

Workshop, London, Ontario.

Ohleth KM, Lenhart JA, Ryan PL, Bagnell CA. 1996. Effect of relaxin on the porcine uterine

insulin-like growth factor system in vivo. Biol Reprod 54(1):291.

Ryan PL, Baum DL, Lenhart JA, Ohleth KM, Bagnell CA. 1996. Relaxin regulates epithelial

cadherin expression in porcine reproductive tissue in vivo. Biol Reprod 54(1):547.

24

Lenhart JA, Bagnell CA. 1995. Localization of connexin 43 gap junction protein during

follicular development in the porcine ovary. Biol Reprod 52(1):101.

Ohleth KM and Bagnell CA. 1995. Expression of E-cadherin in the developing and adult pig

ovary. Biol Reprod 52(1):146.

Ohleth KM, Bagnell CA. 1994. Effect of relaxin on IGF-I secretion by cultured porcine

granulosa cells. Biol Reprod 50(1):273.

Zhang Q, Bagnell CA. 1994. Relaxin induction of tyrosine phosphorylation in porcine granulosa

cells. Biol Reprod 50(1):108.

Ohleth KM, Bagnell CA. 1993. A relaxin-like protein in the avian ovary. Biol Reprod 48(1):93.

Zhang Q, Bagnell CA. 1993. Effect of tyrosine kinase inhibitors on relaxin-induced DNA

synthesis in cultured porcine granulosa cells. Biol Reprod 48(1):493.

Zhang Q, Bagnell, CA. 1993. Autocrine action of relaxin on porcine theca interna cell DNA

synthesis: Interactions with hormones of the insulin-like family in vitro. Presented at the Fourth

International Conference on Pig Reproduction, Columbia, Missouri.

Bagnell CA, Feldman MR, Ohleth KM, Blaschuk O, Ainsworth L. 1992. The

immunohistochemical localization of clusterin in the developing porcine ovary. Biol Reprod

46(1):216.

Zhang, Q, Ohleth KM, Bagnell CA. 1992. Biological action of relaxin in the developing pig

follicle: Effects on cell proliferation and deoxyribonucleic acid (DNA) synthesis in vitro. Biol

Reprod 46(1):217.

Bagnell CA, Zhang Q, Ohleth K, Downey BR, Ainsworth L. 1991. Developmental expression

of the relaxin gene in the porcine corpus luteum. Biol Reprod 44(1):189.

Bagnell CA, Ohleth K, Clark CL, Taylor MT. 1991. Simultaneous detection of relaxin

secretion and gene expression in individual porcine luteal cells. Presented at the Serono

Symposium "Molecular Basis of Reproductive Endocrinology" in Vancouver, British Columbia.

Bagnell CA. 1990. Identification of immunoreactive relaxin in the neurohypophysis of the pig.

Biol Reprod 42(1):184.

Bagnell CA, Tsark W, Tashima L, Downey BR, Tsang BK, Ainsworth L. 1989. Relaxin gene

expression during ovarian follicular development in the pig. 71st Annual Meeting of the

Endocrine Society, Seattle, Washington, p 205.

Bagnell CA, Ali SM, McMurtry JP. 1988. In situ localization of relaxin messenger RNA in the

pig corpus luteum in the cycle, pregnancy and lactation. Biol Reprod 38(1):179.

25

Bagnell CA, Ayau E, Downey BR, Tsang BK, Ainsworth L. 1988. Localization of relaxin

during formation of the corpus luteum. Presented at the 1988 Ovarian Workshop in Tacoma,

Washington.

Bagnell CA, Frando LB, Bryant-Greenwood GD, Downey BR, Tsang BK, Ainsworth, L. 1986.

Localization of relaxin in the pig follicle during preovulatory development. Biol Reprod

34(1):16.

Bagnell CA, Greenwood FC, Bryant-Greenwood GD. 1985. Paracrine relaxin: A role in the

ovarian follicle of the pig and rat. J. Endocrinology 107S:141.

Bagnell CA, Baker NK, Bryant-Greenwood GD. 1985. Immunohistochemical localization of

relaxin in the rat ovary during lactation. Biol Reprod 32(1):90.

Bryant-Greenwood GD, Bagnell CA, Koay ESC, Greenwood FC. 1984. Paracrine role for

follicular and decidual relaxins. Presentation of paper at Montebello Symposium on Gonadal

Proteins and Peptides, Montebello, Canada.

Bagnell CA, Bryant-Greenwood GD. 1984. Plasminogen activator during follicular

development in rat and pig granulosa cells. Presented at the 5th Biennial Ovarian Workshop,

1984, Laramie, Wyoming.

Bagnell CA, Mills T, Stadt H, Gerardot R, Mahesh VB. 1983. Inhibition of Aromatase: A

possible mechanism of androgen-induced atresia. Presented at the 65th Annual Endocrine

Society Meeting, San Antonio, Texas.

Bagnell CA, Mills T, Costoff A, Mahesh, VB 1982. Comparison of histology and ovulation as

measures of ovarian function using a rat model developed to study follicular growth and atresia.

Presented at the Annual Meeting of the Society for Experimental Biology and Medicine,

Southeastern Section, Augusta, GA.

Bagnell CA, Mills T, Costoff A, Mahesh VB. 1981. A model for the study of androgen effects

on follicular atresia. Southeastern Meeting of Endocrinology, Emory University, Atlanta, GA.

POSTDOCTORAL FELLOWS and STUDENTS MENTORED

Dr. Peter Ryan, Postdoctoral Fellow, 1994-1997

Present address: Professor, Dept of Animal & Dairy Science, Mississippi State U.

Dr. Frank Petersen, Research Associate, 2004-2006

Present address: NJ Dept of Agriculture, Division of Animal Health, Trenton, NJ

Dr.Teh-Yuan Ho, Postdoctoral Fellow, 2003-2004; Research Associate 2005-present

26

Graduate students – Primary advisor (current location in parentheses):

Student Yrs Deg Project/Thesis Title

Ashley George 2013 - Ph.D. Role of nursing in maternal programming of

neonatal uterine development

Meredith Camp 2009-2014 Ph.D. Lactocrine signaling and neonatal porcine

reproductive tract development

(Food and Drug Administration, Washington, DC)

Henry Bignell 2011-2014 M.S. Glutamine supplementation on the lipid profile of

colostrum, milk and neonatal adipose tissue

(Cornell University, County Agent)

Kathleen Rahman 2008-2014 Ph.D. Milk-borne bioactive factors: Effects on neonatal

porcine reproductive tissues and uterine function

in adults (started in my lab 9/09)

(Former Teaching Instructor, Rutgers U)

Joseph Chen 2005-2011 Ph.D. Regulation of porcine uterine programming: Effects

of neonatal estrogen and relaxin exposure

(Siemens Healthcare Diagnostics)

Amy Frankshun 2005-2011 Ph.D. The lactocrine role of relaxin in the developing

porcine cervix

(Food and Drug Administration, Rockville, MD)

Emily Lamprecht 2004-2010 Ph.D. Inflammatory responses of horses to intense

exercise and effects of nutritional supplementation

(Cargill Animal Nutrition)

Wenbo Yan 1999-2005 Ph.D. Relaxin action in the reproductive tract: Interaction

with estrogen signaling pathways

(Biology Dept, Nyack College, NY)

Karen Santora 2002-2005 M.S. Effects of relaxin on arthritis and inflammation

(Merck and Company)

Jennifer Neumann 1999-2002 M.S. Production and characterization of recombinant

equine relaxin

(Physician in North Carolina)

27

Graduate students – Primary advisor (con’t):

Student Yrs Deg Project/Thesis Title

Judy Lenhart 1992-1999 Ph.D. Role of relaxin in the control of reproductive tissue

growth. Awards: First Prize, 1996 Cook College

Graduate Research Poster Competition; 1997 GSNB

Teaching Award; (Celgene Corporation)

Kathleen Ohleth 1992-1997 Ph.D. Relaxin: Control of secretion and effects on the

insulin-like growth factor system

(Precise Publications, CEO)

Zhang Qi, M.D. 1989-1994 Ph.D. Role of relaxin in porcine follicular development

and ovulation

(MD, Pathologist)

Graduate students – Member of the thesis committee:

Student Yrs Deg Graduate Program Major Advisor

Chelsee Holloway in progress Ph.D Endo & Anim Biosci L. Quadro

Ali Yasrebi in progress M.S. Endo & Anim Biosci T. Roepke

Seher Yirtici 2016 M.S. Endo & Anim Biosci M. Uzumcu

Jennifer Yang 2016 Ph.D. Endo & Anim Biosci T. Roepke

Allyson Agostini-Dreyer 2014 Ph.D. Nutritional Sciences W. Cohick

Alison Golinski 2013 Ph.D. Endo & Anim Biosci H. John-Alder

Jushen Cheng 2011 M.S. Endo & Anim Biosci W. Cohick

Kristy Longpre 2011 Ph.D. Endo & Anim Biosci L. Katz

Norell Hadzimichalis 2008 Ph.D. Cell & Neurobiology G. Merrill

Brian Leibowitz 2008 Ph.D. Endo & Anim Biosci W. Cohick

AnneMarie Armenti 2007 M.S. Animal Sciences M. Uzumcu

Alvaro Arjona 2006 Ph.D. Animal Sciences D. Sarkar

Jodie Fleming 2006 Ph.D. Animal Sciences W. Cohick

Jill Lindia 2004 M.S. Animal Sciences L. Katz

Meagan Shearer 2003 M.S. Animal Sciences L. Katz

Kim McMunn 2001 M.S. Animal Sciences L. Katz

Bojing Wang 2001 M.S. Animal Sciences W. Cohick

Daniela Maina 1999 Ph.D. Animal Sciences L. Katz

Heather Billings 1998 Ph.D. Animal Sciences L. Katz

Steve Leili 1997 Ph.D. Animal Sciences C. Scanes

Michelle Lane 1996 Ph.D. Animal Sciences B. Jesse

Luquan Wang 1996 Ph.D. Animal Sciences B. Jesse

Gretchen Ritacco 1996 M.S. Animal Sciences P. Schoknecht

Wei-Lun Hung 1995 M.S. Animal Sciences J.P. Advis

Gloria Regisford 1994 Ph.D. Animal Sciences L. Katz

28

Graduate students – External examiner for Ph.D. defense:

Student Yr Institution Thesis Title

Lifu Song 1998 University of Guelph Effects of equine relaxin on the activity of

Guelph, Ontario equine ovarian stromal cells in vitro

J Willcox 2012 University of Guelph The neuroprotective effects of relaxin-2 and

Guelph, Ontario relaxin 3

Undergraduate students - George H. Cook Honors Program

Mindy Feldman, 1991-1992

Thesis: Localization of cadherins in the developing pig follicle

Brian Karolewski, 1992-1993

Thesis: Temporal expression of clusterin gene and protein in the developing ovary

Kuntal Joshi, 1993-1994

Thesis: Cadherin function in the ovarian follicle

Anthony Valentine, 1994-1995

Thesis: Cell adhesion molecules in the porcine ovary: Epithelial cadherin expression

during development.

*First Prize - 1995 Cook College Undergraduate Research Poster Competition

Daniel Baum, 1995-1996

Thesis: Regulation of E-cadherin expression in ovarian cells.

*First Prize - 1996 Cook College Undergraduate Research Poster Competition.

Kathryn McGonigle, 1997-98 Rutgers University Undergraduate Fellow

Thesis: Ovarian Growth: Effects of relaxin and estrogen on connective tissue proteases.

1997 Summer NJ Commission on Cancer Research Fellow

Amy Mallin, 1998-99 Merck/Rutgers Undergraduate Research Fellow

Thesis: Role of E-cadherin in ovarian cell adhesion, apoptosis and cell communication.

Stephanie Dondzil, 1998-99

Thesis: Hormonal control of connective tissue protease activity in ovarian cancer cells.

1999 Summer NJ Commission on Cancer Research Fellow

Kelli French, 1999-2000 Rutgers Undergraduate Research Fellow

Thesis: Characterization of VEGF in porcine reproductive tissues

Stefanie Malkiewicz, 2000-2001 Rutgers Undergraduate Research Fellow

Thesis: Mechanism of growth factor action in an ovarian cancer cell line

2000 Summer NJ Commission on Cancer Research Fellow

29

Undergraduate students - George H. Cook Honors Program (con’t)

Tamiko Yamamoto, 2004-2005 J & J/Rutgers Undergraduate Research Fellow

Thesis: Cross talk between relaxin and estrogen receptor in uterine tissue remodeling

Megan Dilts, 2007-2008 Aresty Undergraduate Research Scholar

Thesis: The role of relaxin on connective tissue remodeling and apoptosis in the neonatal porcine

heart and cervix.

Michael Strug, 2008-2009 Aresty Undergraduate Research Scholar

Thesis: Role of estrogen and relaxin receptors on mouse interpubic ligament sensitivity to relaxin.

Nathalie Sanchez, 2009-2010 Aresty Undergraduate Research Scholar

Thesis: Effects of milk-borne factors on neonatal porcine cardiac development

*First prize – 2009 SEBS Undergraduate Research Poster Competition

Lauren Barron, 2010-2011 Aresty Undergraduate Research Scholar

Thesis: Gut closure in neonatal pigs: Role of colostrum

*First prize – 2011 SEBS Undergraduate Research Poster Competition

Kristene Welch, 2010-2011 Aresty Undergraduate Research Scholar

Thesis: Uterine developmental programming and the impact of lactocrine signaling

*First prize – 2010 SEBS Undergraduate Research Poster Competition

Monica Boulos, 2012-2013 GH Cook Honors Scholar

Thesis: Effects of nursing on porcine cervical development

Nikesh Patel, 2014-2015 GH Cook Honors Scholar

Thesis: Neonatal porcine hepatic cholesterol and triglycerides: Effects of Aminogut

Jessica Lovich, 2014-2015 GH Cook Honors Scholar

Thesis: Effects of duration of nursing from birth on neonatal uterine gene expression

Mary Nasr, 2015-2016 GH Cook Honors Scholar

Thesis: Effects of age and nursing on neonatal porcine small intestine development

Undergraduate Students – Independent Research

Helen Uczkowski, 2011 Douglass STEM Summer Research Experience

Jerika Boulware, 2012 and 2013 Rodkin Science Scholar in support of summer research

Jennifer Wang, 2016-2017 Aresty Program Research Assistant

Project title: Long term effects of nursing from birth on uterine protein during pregnancy in the pig

Summer Internship for Biotechnology High School Students – sponsored Jo Belluardo and

Anya Stoupine during Summer 2008 for a 4 week internship in my laboratory.

30

Cooperative Education Advisor for more than 25 undergraduates since 1988

Academic Advisor for undergraduates majors in Animal Sciences, Biology and

Biotechnology ~ 30 students annually

Independent Research in Animal Sciences (Problems in Animal Sciences; 11:067:494-495)

1989-present; Two students per year

Douglas Project SUPER advisor

1999; Heather Jensen

SERVICE

Professional Service

2017 USDA Grant Review Panel – Animal Reproduction, Member

2009 USDA Grant Review Panel – Animal Reproduction, Member

2008 USDA Grant Review Panel - Animal Reproduction, Member

2007-2008 Society for the Study of Reproduction (SSR), Nominating Committee

Member

2007-2008 SSR, Awards Committee, Member

2000-2001 SSR, Future Meetings Committee, Member

2000 USDA Review Panel – Animal Reproductive Efficiency, Member

1993-1994 SSR, Membership Committee, 1995/96 Chair

1993 NIH-Biochemical Endocrinology Study Section, ad hoc member

1992 NIH Special Study Section - Small Business Innovation Research, ad hoc

member

Rutgers University Activities

2017-2020 Graduate School New Brunswick, Executive Council, Member

2015-2016 TA-GA Professional Development Fund Committee, Member

2008-2011 Busch Biomedical Research Program, Grant reviewer

2007 -pres Graduate School New Brunswick, Biological Sciences Area Committee

2004-2006 Graduate School New Brunswick, Committee of Review

1999-pres University Biosafety Committee, Member

1997-1998 Faculty Panel - Detenurement/dismissal FAS faculty

1996-1999 University Senate, Member

School of Environmental and Biological Sciences Activities

2017-pres SEBS/NJAES Advisory Council, Member

2015-2016 Search Committee for faculty hires in the NJ Institute for Food, Nutrition

and Health, Member

2015 Search Committee for Dept of Ecology, Evolution and Natural Resources,

Assistant Extension Specialist, Chair

31

School of Environmental and Biological Sciences Activities (con’t)

2010 Search Committee for Associate Director of the NJ Institute for Food,

Nutrition and Health, Member

2007 Biochemistry Task Force Committee, Member

2006 Agricultural Experiment Station Budget Committee, Member

2005-2006 College Appointments and Promotions Committee, Co-chair

2003-2005 College Appointments and Promotions Committee, Member

2003-2007 College Faculty Financial Aid Committee

2003 College Grievance Committee, Chair

2002-2008 Special Projects & Tuition Differential Advisory Committee

2000-2001 Cook College Organizational Structural Leadership Strategy Team,

Co-chair

1999-2000 Junior/Senior Colloquium Committee, Member

1994-1998 College Planning Committee, Member

1993-1999 Curriculum and Educational Policy Committee, Member

1992-1993 College Affirmative Action Committee, Chair

1990-2006 G.H. Cook Honors Program Committee, Member

1991 Rutgers Guidance Counselor Program, invited speaker

1991-1993 College Library Representative

Animal Science Department/Biotech Center Activities

2009- pres Pioneers In Endocrinology, organizing committee, Member

2008, 2009 Peer Evaluation Committee (PEC) for Biotech Center, Member

2007, 2016 PEC Committee for Animal Sciences, Chair

2017 PEC Committee for Animal Sciences, Chair

2005 Committee to review Candidate for promotion and tenure, Chair

2002 Committee to review Candidate for promotion to Professor I, Member

1999-2001 Animal Science Chair Advisory Panel, Member

1995-1999 Associate Chair of the Department of Animal Sciences

1993-1995 Departmental Safety Representative

Departmental Committees:

2002-pres Faculty Mentoring Committee for Dr. Mehmet Uzumcu, Chair

1999-pres Faculty Mentoring Committee for Dr. Wendie Cohick, Chair

1996 Evaluating & Rewarding Excellence in Teaching, Chair

1993-1998 Johnson & Johnson Seminar in Reproduction Committee, Chair

Faculty Search Committees:

2015-2016 Endocrine-Epigenetics faculty search, Chair

2008-2009 Endocrine Cluster hire, Ad hoc member

2002-2003 Endocrinology faculty hire, Member

2000-2001 Transgenic faculty hire, Member

2000-2001 Genomics faculty hire, Member

1996-1997 Animal Biotechnologist hire, Chair

1994-1995 Instructor in Reproduction, Chair

1993-1994 Nutrition/genetics faculty hire, Member

32

Graduate Program in Endocrinology and Animal Biosciences

(formerly called Animal Sciences, until 2007)

2014- pres Graduate Program Director

2015, 2017 SEBS Excellence Fellowship Committee, Member

2007-2009 Admissions Committee, Chair

1999-pres TA/GA Appointments Committee, Chair

1995-2009 Academic Standards Committee, Member

1992-1995 Academic Standards Committee, Chair

1990-1992 Admissions Committee, Member

Other Outreach:

Bagnell CA. Sp 2016. Got Milk? Explorations GH Cook Campus Magazine, p.10.

The News Kids, Summer 2015

Television interview by elementary school student journalists in The News Kids program in

Princeton, NJ. Met with students and discussed research on the importance of mother’s milk in

programming development conducted on the Cook Campus farm and in the laboratory.

cv\bagnell 12-8-2017