Curriculum Vitae and Bibliography Caterina Giannini, MD · Personal Information Curriculum Vitae and Bibliography Caterina Giannini, MD Place of Birth: Citizenship: Work Address:

Personal Information

Curriculum Vitae and Bibliography

Caterina Giannini, MD

Place of Birth:

Citizenship:

Work Address:

Present Academic Rank and Position Consultant - Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

Professor of Laboratory Medicine And Pathology - Mayo Clinic College of Medicine and Science

10/2002 - Present

07/2008 - Present

Professor of Neurosurgery - Mayo Clinic College of Medicine and Science 11/2014 - Present

Education

Liceo Classico Statale N. Machiavelli - Diploma, Maturita Classica 1978

University Hospital of Pisa, Italy - MD 1978 - 1984

Department of Neurology, University Hospital of Pisa, Italy - Resident, Neurology 1984 - 1986

University of Verona - Resident, Neurology 1986 - 1987

Peripheral Nerve Center, Mayo Graduate School of Medicine, Mayo Clinic College 1987 - 1989 of Medicine - Research Fellowship

University of Verona - Ph.D., Neurological Science 1988 - 1992

Peripheral Nerve Center, Mayo Graduate School of Medicine, Mayo Clinic College 1989 - 1992 of Medicine - Special Research Associate

Department of Pathology and Laboratory Medicine, Mayo Graduate School of Medicine, Mayo Clinic College of Medicine - Resident, Anatomic Pathology

Department of Pathology and Laboratory Medicine, Mayo Graduate School of Medicine, Mayo Clinic College of Medicine - Fellow, Neuropathology

1992 - 1994

1994 - 1996

Caterina Giannini, MD Page 2 of 57

Certification

Board Certifications

American Board of Pathology

Anatomic Pathology 1997 - Present

Federation Licensing Examination (FLEX)

FLEX 1993 - Present

Foreign Medical Graduate Examination in Medical Sciences

FMGEMS 1991 - Present

Italian Board of Neurology

Neurology 1988 - Present

Italian National Board of Medicine

Internal Medicine 1984 - Present

Mayo Clinic Quality Academy

Mayo Clinic Quality Fellow: Bronze Level Certification 2011

Licensure

Italy 1603 (Medical) 01/1985 - Present

Minnesota 37359 (Medical) 09/1994 - Present

Honors and Awards

Summa Cum Laude - Medical School, University of Pisa 01/1984

Outstanding Resident - Ordine dei Medici, Lucca, Italy 01/1987

Rotary International Scholarship - Awarding Organization 01/1987 - 01/1988

Hobart KB Allebach Fellowship in Pathology Outstanding Resident - Mayo Clinic

01/1994

Arthur Purdy Stout Society yearly student price - Awarding Organization 01/1995

Previous Professional Positions and Major Appointments

Consultant in Anatomic Pathology and Neuropathology - Regional Hospital of Treviso, Treviso, Italy

1996 - 1999

Assistant Professor in Laboratory Medicine And Pathology - Mayo Clinic College of Medicine and Science

07/1999 - 09/2004

Senior Associate Consultant - Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

10/1999 - 10/2002

Associate Professor in Laboratory Medicine And Pathology - Mayo Clinic College of Medicine and Science

10/2004 - 06/2008

Professional and Community Memberships, Societies, and Services


Professional Memberships and Services

American Association of Neuropathologists

Member 01/1994 - Present

Moderator 06/2018

International Academy of Pathology

Italian Division

Neuropathology Club


Italian Association of Neuropathology


Peripheral Nerve Society


Society for Neuro-Oncology


United States and Canadian Academy of Pathology


Journal Responsibilities

Journal Editorial Responsibilities

Acta Neuropathologica

Editorial Board Member 06/2013 - Present

Journal Other Responsibilities

Acta Neuropathologica Communications

Ad Hoc Reviewer 01/2013 - Present

American Journal of Surgical Pathology

Ad Hoc Reviewer

Reviewer 01/2000 - Present

Brain Pathology


Brain Tumor Pathology

Ad Hoc Reviewer


Journal of Neuro-Oncology


Journal of Neuropathology and Experimental Neurology

Ad Hoc Reviewer


Journal of Rheumatology

Ad Hoc Reviewer


Modern Pathology

Ad Hoc Reviewer


Educational Activities


Teaching Intramural

Leader of the weekly rounds Neurooncology group, Regional Hospital of Treviso Treviso, Italy

09/1996 - 09/1999

Leader of the monthly review group Pediatric Neurooncology Group of the Veneto Region Italy

01/1997 - 09/1999

Classification and grading of glial tumors in children Department of Pediatric Oncology, University of Padova Padova, Italy

04/1997

Tumori cerebrali dell'infanzia Professore a contratto Scuola di Specializzazione in Neuropsichiatria Infantile, Universita' degli Studi di Padova Italy

01/1998 - 01/1999

Meningeal Infections - Pathology Department of Anatomic Pathology, University of Verona Verona, Italy

04/1998

Classification and grading of diffuse gliomas Course of Diagnostic Histopathology of Central and Peripheral Nervous System Neoplasms Department of Pathology, Regional Hospital of Treviso Treviso, Italy

05/1998

Neuroradiological Correlations in Surgical Neuropathology Course of Diagnostic Histopathology of Central and Peripheral Nervous System Neoplasms Department of Pathology, Regional Hospital of Treviso Treviso, Italy

05/1998

Pathology Course: Tumors of the Nervous System 1 hour contact per year Mayo School of Health-Related Sciences, Program in Physical Therapy Rochester, Minnesota

01/1999 - Present

Central nervous sytem neoplasms: neuroradiological correlations in differential diagnosis Department of Neurology, University of Verona Verona, Italy

04/1999

Viral and Bacterial CNS Infections - Pathology Department of Anatomic Pathology, University of Verona Verona, Italy

04/1999

Neuro-oncology Work Conference - Multidisciplinary Weekly Conference, (Neurology, neurosurgery, neuroradiology, neuropathology and neurooncology), St. Marys Hospital Rochester, Minnesota

10/1999 - Present

Monday Night Slide Conference 1-2 hours contact per year Department of Pathology Rochester, Minnesota

01/2000 - Present

Leigh's Disease CPC conference Department of Neurology Rochester, Minnesota

04/2000


Pathology of the Optic Nerve Department of Ophthalmology Rochester, Minnesota

04/2000

Optic Nerve for the Surgical Pathologist Department of Pathology Rochester, Minnesota

05/2000

Optic nerve choristoma and optic nerve aspergillosis, unusual lesions involving the optic nerve Neurology-Neurosurgery Grand Round Rochester, Minnesota

05/2000

Astrocytic tumors: WHO 2000 classification, differential diagnosis and pitfalls Department of Pathology Rochester, Minnesota

05/2000

Astrocytomas: diagnostic work-up, grading and pitfalls ASCP teleconference # 2080

06/2000

Introduction to surgical neuropathology Department of Pathology Rochester, Minnesota

08/2000

Classification and grading of gliomas (astrocytic neoplasms) Department of Pathology Rochester, Minnesota

11/2000

Diffuse axonal injury vs Anoxic injury - case discussion Mortality & Morbidity Conference - Department of Neurosurgery Rochester, Minnesota

11/2000

Head Trauma - Case discussion Mortality & Morbidity Conference - Department of Neurosurgery Rochester, Minnesota

12/2000

Pathology Course, Year II - Path-Neuro Unit: Tumors of the Nervous System; Peripheral Nerve Diseases 3 hours contact per year Mayo Medical School Rochester, Minnesota

01/2001 - Present

Tumors of the Nervous System: Neuroimaging and Pathology - Correlation and Differential Diagnosis Department of Pathology Rochester, Minnesota

01/2001

Cerebral toxoplasmosis in SLE - Case discussion. Grand Rounds, Department of Rheumatology Rochester, Minnesota

02/2001

Sciatic nerve neuromuscular choristoma Neurology/Neurosurgery Grand Rounds

07/2001

Ectopic craniopharyngioma of the CPA in Gardner syndrome Neurology/Neurosurgery Grand Round

02/2002

Primary CNS vasculitis involving the cauda equina Neurology/Neurosurgery Grand Round

02/2002


Erdheim-Chester Disease 09/2002

Neurology/Neurosurgery Grand Round

Practical Surgical Pathology Course, Case 11: Reactive gliosis, differential diagnosis in Surgical Neuropathology MML, Rochester MN Rochester, Minnesota

09/2003

Neurology and Neurosurgery Grand Round: Aortic dissection presenting as coma MML, Rochester MN

12/2003

Neurology and Neurosurgery Grand Round: Cerebral sarcoidosis presenting as sagittal sinus thrombosis-case discussion MML, Rochester MN

01/2004

Neurology and Neurosurgery Grand Round: Diffuse astrocytoma (Grade 3 (of 4) fibrillary astrocytoma) MML, Rochester MN

02/2005

Pediatric Tumor Board: Atypical Teratoid/Rhabdoid tumor MML, Rochester MN

03/2005

Neurology and Neurosurgery Grand Round: Sarcoidosis of the CNS MML, Rochester MN

03/2005

Neurology and Neurosurgery Grand Round: Primary CNS angiitis (Granulomatous vasculitis) and Cerebral amyloid angiopathy associated with granulomatous vasculitis MML, Rochester MN

06/2005

Neurology Subspecialty Conference: Intracortical ependymoma as a case of chronic seizures MML, Rochester MN

07/2005

Neurology and Neurosurgery Grand Round: Supratentorial high grade ependymoma in adults MML, Rochester MN

08/2005

Neurology and Neurosurgery Grand Round: Primary CNS Angiitis MML, Rochester MN

08/2005

Neurology Department Clinicopathological conference: Grade 3 fibrillary astrocytoma presenting with seizures MML, Rochester MN

11/2005


Mentorship

Miller, Dylan (Associate Consultant) Description: Dr. Giannini has mentored Dr. Miller in a multidisciplinary project focusing on Primary CNS vasculitis. Current Status: Pathology Consultant in Salt Lake City, Utah. Outcome: A main pathological paper: "Biopsy findings in Primary Angiitis of the Central Nervous System" Miller DV, Salvorani C, Hunder GG, Brown RD, Parisi JE, Christianson TJ, Giannini C. has been submitted for review to Brain Pathology. Two additonal collaborative publications resulted from the collaboration: 1. Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Weigand SD, Miller DV, Giannini C, Meschia JF, Huston J 3rd, Hunder GG. Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol. 2007 Nov; 62(5):442-51. 2. Salvarani C, Giannini C, Miller DV, Hunder G. Giant cell arteritis: Involvement of intracranial arteries. Arthritis Rheum. 2006 Dec 15;55(6):985-9.

Rynearson, Amanda (Research Technician) Description: Dr. Giannini has mentored Amanda primarily in the area of tissue banking and tranlational research. Under Dr. Giannini's supervision, she also completed a project. Current Status: Physician Assistant Student in Madison, WI. Outcome: Rynerson AL, Giannini C, Rodriguez F, Passe SM, Randolph JL, Blanchard TW, McElwain T, Marler RJ, Jenkins RB. A subset of canine oligodendroglial tumors share genetic similarities with human oligodendrogliomas., which resulted in a poster presentation at the Society of Neuro-Oncology, in Houston TX, November 2007 (manuscript in preparation).

Cady, Francois (Haematopathology Fellow) Description: Together with Dr. A Dogan, a hematopathologist, Dr. Giannini mentored Dr. Cady on a project looking at molecular genetic characteristics of primary CNS lymphoma. Current Status: Outcome: The project was presented at the US-Canadian Academy of Pathology Annual Meeting (2007). A manuscript has been recently submitted for consideration for publication to the J Clin Oncol. Cady FM, Law ME, Giannini C, Porter AB, O'Neill BP, Decker PA, Kurtin PJ, Dogan A, Remstein ED. Del(6)(q22) and BCL6 rearrangements in primary central nervous system lymphoma (PCNSL) are indicators of an aggressive clinical course. J Clin Oncol.

Porter, Alyx (Neurology Resident) Description: Dr. Giannini mentored Dr. Porter on a project looking at the effect of corticosteroids on primary CNS lymphoma, possibly interfering iwth diagnosis. Current Status: Neuro-Oncology Consultant at Mayo Clinic Arizona. Outcome: The project was presented at the American Academy of Neurology (2007) and led to a manuscript at present under review in Ann Neurol. Porter AB, Giannini C, Kaufmann T, Lucchinetti CF, Wu W, Decker PA, Atkinson JL, O'Neill BP. Primary Central Nervous System Lymphoma (PCNSL) can bee histologically diagnosed after previous corticosteroid use. A pilot study to determine whether corticosteroids prevent the diagnosis of PCNSL Ann Neurol.

01/2003 - 01/2006

01/2004 - 01/2011

01/2006 - 01/2007

01/2007 - 01/2008


Rodriguez, Fausto (Research Fellow) Description: Dr. Rodriguez before was a Pathology Resident from 2002-2005 and a Neuropathology Fellow from 2005-2007. He completed an NINDS training grant. Dr. Giannini was a research training Senior Faculty and Primary Research Mentor of Dr. Rodriguez under the NINDS T32 NS07494 Research training program in Neuro-Oncology (Director Dr. BP O'Neill). Current Status: Assistant Professor Neuropathology Department at Johns Hopkins in Baltimore, MD. Outcome: Projects completed under Dr. Giannini's supervision during Dr. Rodriguez's residency, fellowship and training training grant: 1. Rodriguez F, Scheithauer BW, Ockner DM, Giannini C. Am J Surg Pathol 2004; 28:139-42. 2. Rodriguez FJ, Crum BA, Krauss WE, Scheithauer BW, Giannini C. Mod Pathol. 2005; 18:710-8. 3. Rodriguez F, Link MJ, Driscoll, CL, Giannini C. Neurosarcoidosis mimicking meningioma Arch Neurol. 2005; 62:148-9. 4. Rodriguez FJ, Brown RD, Mohr JP, Piepgras DG, Thielen K, Blume RS, Connolly H, Petty G, Giannini C. Embolic atrial myxoma with neoplasti caneurysm formation and hemorrhage: a diagnostic challenge. Neuropathol Appl Neurobiol. 2006;32:213-6. 5. Links Leenstra JL, Rodriguez FJ, Frechette CM, Giannini C, Stafford SL, Pollock BE, Schild SE, Scheithauer BW, Jenkins RB, Buckner JC, Brown PD. Central neurocytoma: management recommendations based on a 35- year experience. Int J Radiat Oncol Biol Phys. 2007; 67:1145-54. 6. Rodriguez FJ, Eberhard C, O'Neill BP, Slezak J, Burger PC, Goldthwaite P, Wu W, Giannini C. Histopathologic grading of adult medulloblastomas. Cancer. 2007;109:2557-65. 7. Rodriguez FJ, Atkinson JL, Giannini C. Massive sellar and parasellar schwannoma. Arch Neurol. 2007;64:1198-9. 8. Rodriguez FJ, Thibodeau SN, Jenkins RB, Schowalter KV, Caron BL, O'Neill BP, David James C, Passe S, Slezak J, Giannini C. MGMT Immunohistochemical Expression and Promoter Methylation in Human Glioblastoma. Appl Immunohistochem Mol Morphol. 2008;16:59-65. 9. Rodriguez FJ, Perry A, Gutmann DH, O'Neill BP, Leonard J, Bryant S and Giannini C. Gliomas in neurofibromatosis type 1: a clinicopathological study of 100 patients.

01/2007 - 01/2008

Van Gompel, Jamie (Fellow) Description: Dr. Giannini has mentored Dr. Van Gompel in mulitple projects regarding esthesioneuroblastoma, carcinoid tumor and cortical ependymoma, an unusual variant of ependymoma occuring supratentorially with a superficial location and associated with relatively favorable prognosis. Current Status: Senior Associate Consultant Department of Neurosurgery at Mayo Clinic in Rochester, MN. Outcome: The collaboration resulted in multiple peer-reviewed publications: Van Gompel JJ, Giannin C, Olsen KD, Moore E, Piccirilli M, Foote RL, Buckner JC, Link MJ. Long-term outcome of esthesioneuroblastoma; hyams grade predicts patient survival. J Neurol Surg B Skull Base. 2012 Oct;73(5):331-6. Noe K, Sulc V, Wong-Kisiel L, Wirrell E, Van Gompel JJ, Wetjen N, Britton J, So E, Cascino GD, Marsh WR, Meyer F, Horinek D, Giannini C, Watson R, Brinkmann BH, Stead M, Worrell GA. Long-term outcomes after nonlesional extratemporal lobe epilepsy surgery. JAMA Neurol. 2013 Aug;70(8):1003-8. Mallory GW, Fang S, Giannini C, Van Gompel JJ, Parney IF. Brain carcinoid metastases: outcomes and prognostic factors. J Neurosurg. 2013 Apri;118(4):889-95. Zakaria T, Noe K, So E, Cascino GD, Wetjen N, Van Gompel JJ, Marsh WR, Meyer FB, Giannini C, Watson RE, Worrell GA. Scalp and intracranial EEG in medically intractable extratemporal epilepsy with normal MRI. ISRN Neurol. 2012; 2012:942849. Van Gompel JJ, Koeller KK, Meyer FB, Marsh WR, Burger PC, Roncaroli F, Worrell GA, Giannini C. Cortical ependymoma; an unusual epileptogenic lesion. J Neurosurg. 2011 Apr;114(4):1187-94. Van Gompel JJ, Stead SM, Giannini C, Meyer FB, Marsh WR, Fountain T, So E, Cohen-Gadol A, Lee KH, Worrell GA. Phase I trial: safety and feasibility of intracranial electroencephalography using hybrid subdural electrodes containing macro- and microelectrode arrays. Neursurg Focus. 2008 Sep;25(3):E23.

01/2009 - 01/2013


Bernardo, Christine (Visiting Physician) Description: Dr. Giannini mentored Dr. Bernardo in her approach to Neuropathology and Neuro-Oncology. She also mentored her in a project on intravascular mucinosis, a rare cause of stroke. Current Status: Attending pathologist at St. Luke's Hospital Manilo, Phillippines. Outcome: Bernardo MC, Graff-Radford J, Menke J, Hallemeier C, Boes CJ, Lewis M, Scheithauer B, Giannini C. Erratum to: Intravascular mucinosis: a rare cause of cerebral infarction. Acta Neuropathol. 2011 Sep; 122(3):379.

Jentoft, Mark (Fellow) Description: Dr. Jentoft was a neuropathology fellow. Current Status: Senior Associate Consultant in Department of Pathology at Mayo Clinic Rochester. Outcome: Menke JR, Jentoft ME, Dogan A, Avent JM, Miller DV, Giannini C. Periventricular white matter immunoglobulin lambda light chain depostion disease diagnosed by proteomic analysis. Acta Neuropathol. 2012 Aug; 124(2):293-5. Jentoft M, Giannini C, Rossi S, Mota R, Jenkins RB, Rodriguez FJ. Oligodendroglial tumors with marked desmoplasia; clinicopathologic and moelcular features of 7 cases. Am J Surg Pathol. 2011 Jun; 35(6):845-52. Jentoft M, Giannini C, Cen L, Scheithauer BW, Hoesley B, Sarkaria JN, Abell-Aleff PC, Rodriguez EF, Li Y, Rodriguez FJ. Phenotypic variations in NF1-associated low grade astrocytomas: possible role for increased mTOR activation in a subset. Int J Clin Exp Pathol. 2010 Dec 12;4(1):43-57.

Kisibash, Sani (Fellow) Description: Dr. Giannini has mentored Dr. Kisibash in a project regarding TMZ response of anaplastic astrocytomas, with/without IDH1 mutation. Current Status: Hematology/Oncology Fellow Mayo Clinic Rochester Outcome: Paper in review.

Leeper, Heather (Fellow) Description: Dr. Giannini is mentoring Dr. Leeper in a project regarding natural history of low grade (WHO grade II) gliomas and molecular subtyping. Current Status: Neuro-oncology fellow at Mayo Clinic Rochester. Outcome:

Ida, Cristiane (Fellow) Description: Dr. Giannini has mentored Dr. Ida in multiple projects related to neuro-oncology and in particular pleomorphic xanthoastrocytoma resulting in multiple publications and meeting presentations. Current Status: Neuropathology Fellow at Mayo Clinic in Rochester, MN. Outcome: Ida CM, Vrana JA, Rodriguez FJ, Jentoft ME, Caron AA, Jenkins SM, Giannini C. Immunohistochemistry is highly sensitive and specific for detection of BRAF V600E mutation in pleomorphic xanthoastrocytoma. Acta Neuropathologica Communications 2013, 1:20. Ida CM, Lambert SR, Rodriguez FJ, Voss JS, McCann BE, Seys AR, Halling KC, Collins VP, Giannini C. BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern. J Neuropathol Exp Neurol. 2012 Jul;71(7):631-9.

01/2010 - 01/2011

01/2010 - 01/2012

01/2012 - Present

01/2012 - Present

01/2012 - 01/2014

Academic Career Development

DLMP Faculty 15 - Blogs & Podcasts Anatomic Pathology Division Meeting Rochester, Minnesota

04/2017

DLMP Faculty 15 - Copyright Anatomic Pathology Division Meeting Rochester, Minnesota

05/2017


Institutional/Departmental Administrative Responsibilities, Committee Memberships and Other Activities

Mayo Clinic

Department of Education Administration

Mayo Clinic College of Medicine and Science

Alumni Member 01/1994 - Present

Mayo Clinic Committees

Mayo Clinic Research Committee

Biospecimens Subcommittee

Chair 01/2007 - 06/2011

Mayo Clinic in Rochester

Department of Laboratory Medicine and Pathology

Continuous Improvement Committee

Consultant Satisfaction

Division of Anatomic Pathology


Neuropathology

Working Group Leader

Tissue Registry

Co-Director 01/2006 - Present

Mayo Clinic Cancer Center

Mayo Clinic Cancer Center - Rochester

Neuro-Oncology Program

Executive Committee Member 01/2003 - Present

Mayo Clinic Rochester Committees

Mayo Clinic Rochester - Executive Board

Research Committee

Biospecimen Trust Oversight Group (BTOG)

Member 01/2007 - 06/2011

Biospecimens Subcommittee

Member 01/2005 - 01/2007

Chair 01/2007 - 06/2011

Presentations Extramural

National or International

Invited

Nerve fiber regeneration after focal nerve injury: pathologic events and mechanisms XIth International Congress of Neuropathology Kyoto, Japan

Axoglial dysjunction: a critical appraisal of definition, techniques and previous results Peripheral Neuropathy Association St. Paul, Minnesota

Ultrastructural morphometric analysis of human sural nerve biopsies European Association for the Study of Diabetes Stockholm, Sweden

09/1990

06/1994

09/1995


La biopsia di nervo periferico Congresso Nazionale della Societa' Italiana di Anatomia Patologica Pisa, Italy

I tumori del nervo periferico XLVII Congresso Nazionale della Societa' Italiana di Neurochirurgia Trieste, Italy

Neuropatologia chirurgica e neuroradiologia, interdipendenza e sinergia Congresso Nazionale della Societa' Italiana di Neurologia Verona, Italy

Microglia in Brain Tumors, Special Course on Microglia in Neuropathology Course Directors DW Dickson and RA Sobel American Association of Neuropathologists Denver, Colorado

Conventional Histopathology in Classification and Prognostication of Astrocytic Tumores. Course Organizer C. Raffel Society of Neuro-Oncology San Diego, California

Frank B. Walsh Session North American Neuro-Ophthalmology Society Meeting Snowbird, Utah

Gliomas of childhood - Childhood Brain Tumor Symposium Societa' Italiana Anatomia Patologica e Citologia Genova, Italy

Surgical neuropathology of evacuated intracerebral hematomas Societa' Italiana Anatomia Patologica e Citologia Florence, Italy

Case presentation: Maturing ganglioneuroma Presented at the 46th Diagnostic Slide Session American Association of Neuropathology

International Symposium: Multidisciplinary Approach to brain and spinal cord tumors Diffuse gliomas, a practical approach to diagnosis. Workshop with multisciplinary discussion of 8 cases (4 hour). Manila, Philippines

Symposium: Recurrent gliomas, therapeutic approaches. Biology of malignant gliomas. Genoa, Italy

Case presentation presented at the 47th Diagnostic Slide Session American Association of Neuropathology, held in conjunction with International Society of Neuropathology

Gliomas: An Update; Clinical Trials in NeuroOncology: Central Review and Tissue Banking; Case Presentation and Discussion NeuroOncology in the Philippines: A Research Retreat and Annual Meeting Manila, Philippines

Neurooncology Trial Activity Alliance for Clinical Trial in Oncology Chicago, Illinois

05/1997

10/1998

10/1999

06/2002

11/2002

02/2003

10/2003

09/2004

06/2005

01/2006

02/2006

09/2006

01/2013

03/2013


Pleomorphic xanthoastrocytoma: An Update; Low grade gliomas; Classification and grading Janpanese Society of Neuropathology Tokushima, Japan

Lower Grade Diffuse Gliomas:integrated histological and molecular diagnosis Advanced course on Surgical Neuropathology: the next generation step in brain tumor classification Trento, Italy

Gliomi di basso grada: inquadramento istopatologico ed epidemiologia 2014 XXennale della Neurochirurgia di Bolzano Bolzano, Italy

PCNS lymphoma & so called prelymphomatous conditionandmoderator of a session Platform presentation AANP Annual Meeting Denver, Colorado

PXA chapter update and HPC chapter update panel member WHO Classification of Tumours of the Central Nervous System Heidelberg, Germany

Grade II and III Gliomas: New Insights Department of Pathology, Penrose Hospital Colorado Springs, Colorado

Update on Mayo Brain SPORE Pathology Core Panel Member Winter SPORE meeting Boston, Massachusetts

Embryonal Tumors WHO CNS Tumor Classification 2016: Update and Practical Implications Treviso, Italy

Grade II-III Gliomas WHO CNS Tumor Classification 2016: Update and Practical Implications Treviso, Italy

PXA and MEW Entities WHO CNS Tumor Classification 2016: Update and Practical Implications Treviso, Italy

Update on Pathology activities for Alliance NeuroOncology trials Alliance for Clinical Trials in Oncology November 2016 Group Meeting Chicago, Illinois

WHO 2016 classification of CNS tumors: an update High Light Lecture University of Manchester Manchester, United Kingdom

WHO 2016 classification of CNS tumors Tutorial 2017 Mayo Clinic Pathology Update: A Tribute to the Career of Kevin O. Leslie, MD Scottsdale, Arizona

Mayo Brain SPORE - Pathology Core NIH Brain SPORE workshop Durham, North Carolina

05/2014

10/2014

12/05/2014 - 12/06/2014

06/2015

06/2015

10/2015

03/31/2016

05/2016

05/2016

05/2016

11/04/2016

11/2016

01/2017

03/21/2017


Invited Faculty at the Walsh Society Panel Member North American Neuro-Ophthalmology Society - Walsh Society City: Washington DC Washington, District of Columbia

An overview on histopathology, genetics and molecular biology High Light Lecture Cerebral Gliomas: Combined Therapeutical Strategies Venice, Italy

Update of NeuroOncology Activities of the Neuropathology Cadre Alliance for Clinical Trials in Oncology November 2017 Group Meeting Chicago, Illinois

Update of NeuroOncology Activities of the Neuropathology Cadre Panel Member Alliance for Clinical Trials in Oncology November 2017 Group Meeting. Chicago, Illinois

NeuroOncology lecture and Slide seminar High Light Lecture 3rd Annual Conference of the Neuropathology Society of India (NPSICON 2018) Lucknow, India

Oral

Ciclo di recupero del RTF nel morbo di Parkinson: analisi delle componenti tardive R2-R3 Societa' Italiana di EEG e Neurofisiologia Clinica Viareggio, Italy

Ciclo di recupero del RTF nella sindrome di Meige: analisi delle componenti tardive R2-R3. Societa' Italiana di EEG e Neurofisiologia Clinica Viareggio, Italy

Evaluation of basic mechanisms of inhibitory phenomena of recovery cycle of trigemino facial reflex Congresso Societa' Italiana di Neuroscienze Pisa, Italy

Numbers and sizes oh MF and UMF regenerating after single crush, multiple crush and autologous graft 3rd European meeting of Neuropathology Verona, Italy

Defective attachment of myelin at nodes of Ranvier in a variety of congenital neuropathy Peripheral Neuropathy Association Oxford, United Kingdom

Defective attachment of myelin at nodes of Ranvier in a variety of congenital neuropathy Peripheral Neuropathy Association Oxford, United Kingdom

Pericyte degeneration and basement membrane reduplication of endoneurial microvessels is associated with severity of diabetic polyneuropathy 118th Annual meeting of the American Neurological Association Boston, Massachusetts

04/02/2017

05/2017

11/2017

11/03/2017

02/17/2018

01/1986

01/1986

01/1986

09/1988

08/1990

08/1990

10/1993


Basement membrane reduplication and pericyte degeneration of endoneurial microvessels compared in diabetic and other neuropathies XIIth International Congress of Neuropathology Toronto, Ontario, Canada

Case presentation: Intracranial fibromatosis 36th Diagnostic Slide Session - American Association of Neuropathology San Antonio, Texas

Case presentation: Malignant peripheral nerve sheath tumor with glandular differentiation. Diagnostic Slide Session - Canadian Association of Neuropathology Jasper, Alberta, Canada

Case presentation: Erdheim-Chester disease. 37th Diagnostic Slide Session, American Association of Neuropathology Vancouver, British Columbia, Canada

Classification and grading of diffuse gliomas Presented at the Course of Diagnostic histopathology of central and peripheral nervous system neoplasms Department of Pathology, Regional Hospital of Treviso Trevixo, Italy

Neuroradiological Correlations in Surgical Neuropathology Presented at the Course of Diagnostic histopathology of central and peripheral nervous system neoplasms Department of Pathology, Regional Hospital of Treviso Treviso, Italy

Case Presentation - Slide seminar SL # 15, Brain Tumors XXII International Congress of the International Academy of Pathology Nice, France

Practical Surgical Pathology Course; Case 8: meningioma, classification and grading MML, Rochester, MN

Case presentation: Optic Nerve Choristoma 42nd Diagnostic Slide Session - American Association of Neuropathology Chicago, Illinois

09/1994

06/1995

09/1995

06/1996

05/1998

05/1998

10/1998

07/2000

06/2001

Case 11: reactive gliosis, differential diagnosis in Surgical Neuropathology 07/2002

Case presentation: Solitary fibrous tumor of the CP angle with salivary gland heterotopia 44th Diagnostic Slide Session - American Association of Neuropathology Orlando, Florida

Case presentation: Embolic/metastatic cardiac myxoma 45th Diagnostic Slide Session - American Association of Neuropathology Cleveland, Ohio

Practical Surgical Pathology Course: Case 24: Esthesioneuroblastoma MML, Rochester MN

International Surgical Pathology Course Case discussion of 5 cases MML, Rochester MN Treviso, Italy

Practical Surgical Pathology Course Case discussion MML, Rochester MN

06/2003

06/2004

09/2005

05/2006

09/2006


Brain SPORE - Pathology Core Activities SPORE Winter Meeting Scottsdale, Arizona

Glial Tumors and Presentation of 8 Clinicopatological Cases Corso Neuropatologia per Specializzandi di Anatomia Patologica Rome, Italy

Case Presentation USCAP Annual Meeting Vancouver, British Columbia, Canada

Case 3 - Evening Seminar AANP Chicago, Illinois

Update on Alliance Clinical Trials - NeuroOncology Alliance for Clinical Trials in Oncology Summer 2012 Group Meeting Chicago, Illinois

Slide Review Johns Hopkins Neuropathology Visit Baltimore, Maryland

Mayo Brain Spore Pathology Core Mid-Winter Brain Spore Retreat Birmingham, Alabama

Cerebral Amyloid Angiopathy USCAP Academy of Pathology Baltimore, Maryland

TCGA LGG Data Analysis TCGA LGG Data Analysis Workshop Houston, Texas

A New IDH1/2 PCR Assay for One-Step Detection of 12 IDH1 and IDH2 Mutation in Glioma 4th Quadriennal Meeting World Federation of Neurooncology San Francisco, California

Update on NeuroOncology Trials Alliance for Clinical Trials in Oncology Fall Meeting Chicago, Illinois

Update on Mayo brain spore pathology core activities SPORE Mid-Winter Retreat San Francisco, California

Classification & Grading of Diffuse Gliomas Who's Next? Haarlem, Netherlands

Pleomorphic Xanthoastrocytoma: An UPdate; Low grade gliomas; Classification & grading Japanese Society of Neuropathology Tokushima, Japan

Report on NeuroOncology Group Activity Alliance for Clinical Trials on Oncology May 2014 Group Meeting Chicago, Illinois

Diagnostic Slide Session Annual Meeting of American Association of Neuropathologists Portland, Oregon

01/2012

02/2012

03/2012

06/2012

06/2012

08/2012

02/2013

03/2013

10/2013

11/2013

11/2013

01/2014

05/2014

05/2014

05/2014

06/2014


Update on molecular advances in adult diffuse gliomas Oncologia Conferencias de Invierno Buenos Aires, Argentina

WHO Classification and grading of adult diffuse gliomas Oncologia Conferencias de Invierno Buenos Aires, Argentina

Report on Alliance NeuroOncology Clinical Trials Alliance for Clinical Trials in Oncology November 2014 Group Meeting Chicago, Illinois

SPORE Pathology Core & Porject Support Update Round Table SPORE winter retreat Houston, Texas

BRAF mutations Conference / MeetingPanel Member and Plenary Annual USCAP Meeting (2015 Neuropathology Evening Specialty Conference) Boston, Massachusetts

Central Nervous System Lymphoma Conference / MeetingPanel Member and Plenary Annual USCAP Meeting (AANP Companion Society Meeting (CSM)) Boston, Massachusetts

NeuroOncology Pathology Cadre Update Alliance for Clinical Trials in Oncology May 2015 Group Meeting Chicago, Illinois

TBD Asian Society for Neurooncology Manila, Philippines

Pathology and Neurooncology Committee - Trial Update Round Table; Conference/Meeting Alliance for Clinical Trials in Oncology - November 2015 Group Meeting Rosemont - Chicago, Illinois

Short course Peripheral Nerve Panel member / conference/meeting USCAP Seattle, Washington

2016 WHO classification of CNS tumors: An Update Italian Association of Neuropathology Rome, Italy

Pleomorphic xanthoastrocytoma & Diagnostic Slide Seminar Moderator Abstract & Moderator American Association of Neuropathologists Balitmore, Maryland

Pleomorphic Xanthoastrocytoma: a chromosomal array analysis 11th European Congress of Neuropathology Bordeaux, France

Recurrent Copy Number Alterations in Classic and Anaplastic Pleomorphic Xanthoastrocytoma: characterization of 40 cases by SNP array Society for NeuroOncology Annual Meeting Scottsdale, Arizona

PN short course USCAP 2017 San Antonio, Texas

08/2014

08/2014

11/2014

01/2015

03/2015

03/2015

05/2015

09/2015

11/2015

03/16/2016

05/26/2016 - 05/28/2016

06/17/2016

07/06/2016 - 07/09/2016

11/17/2016 - 11/20/2016

03/09/2017


TBD Abstract World Federation of Neurooncology Societies Zurich, Switzerland

Update of the NeuroOncology Cadre Conference/Meeting Alliance for Clinical Trials in Oncology

DSS slide seminar moderator American association of neuropathologists Garden Grove, California

Clinical and molecular analyses of long-term survivors of glioblastoma Abstract 22nd Annual Scientific Meeting and Education Day San Francisco., California

Vascular Lesions of the Central Nervous System Mimicking Vasculitis AANP Companion Society Meeting USCAP Annual Meeting Vancouver, British Columbia, Canada

Electron Microscopy in the diagnosis of CNS tumors: dead or alive? USCAP 2018 SOCIETY OF ULTRASTRUCTURAL PATHOLOGY COMPANION MEETING USCAP Annual Meeting Vancouver, British Columbia, Canada

SC05 short course presentation USCAP Annual Meeting Vancouver, British Columbia, Canada

Poster

Angiocentric Glioma 15th International Symposium Pediatric NeuroOncology Toronto, Ontario, Canada

Interlaboratory Reproducibility of Mutant IDH1 Testing 17th Annual Meeting of Society for NeuroOncology Washington, District of Columbia

Phase II Trial of Pre-Irradiation and Concurrent Temozolomide in Patients with Newly Diagnosed Anaplastic Oligodendrogliomas and Mixed Anaplastic Oligodendrogliomas 17th Annual Meeting of Society for NeuroOncology Washington, District of Columbia

Immunohistochemistry is Highly Sensitive and Specific for Detection of BRAF V600E Mutation in Pleomorphic Xanthoastrocytoma Annual Meeting of AANP Charleston, South Carolina

Thalamic Pilocytic Astrocytomas 16th International Symposium on Pediatric Neurooncology Singapore

05/2017

05/2017

06/2017

11/2017

03/2018

03/2018

03/2018

06/2012

11/2012

11/2012

06/2013

07/2014


Grading Considerations for Meningeal Solitary Fibrous Tumor/HemangiopericytomaGenome-wide Methylation Profiling of Low-grade and Anaplastic Pleomorphic Xanthoastrocytoma abstracts USCAP Annual Meeting Vancouver, British Columbia, Canada

Regional

Invited

Frank B. Walsh Session 29th Annual North American Neuro-Ophthalmology Society Meeting Snowbird, Utah

Diagnosis of diffuse gliomas, something old, something new Lake Superior Society of Pathology Duluth, Minnesota

Molecular Diagnosis of diffuse gliomas: a practical approach Italian Association of Neuropathology Saluzzo, Italy

Honorary Symposium for Dr. PJ Dyck and Dr. AG Engel Centennial Celebration of the Mayo Neurology Department

Role of Brain Biopsy in Clinical Neurology Italian Society of Neurology Florence, Italy

Oral

Classification and grading of glial tumors in children Department of Pediatric Oncology, University of Padova Padova, Italy

Meningeal Infections Department of Anatomic Pathology, University of Verona Verona, Italy

Neuroradiological Correlations in Surgical Neuropathology Department of Neurosurgery, Mayo Clinic Rochester, Minnesota

Central nervous system neoplasms: neuroradiological correlations in differential diagnosis Department of Neurology, University of Verona Verona, Italy

Viral and Bacterial CNS Infections Department of Anatomic Pathology, University of Verona Verona, Italy

Anterior cerebral artery aneurysm, subarachnoid hemorrhage and vasospasm - case discussion. Mortality and Morbidity Conference Deparment of Neurosurgery Rochester, Minnesota

Nonspecific dysembrioplastic neuroepithelial tumor - Case discussion - Seizure Conference Department of Neurology Rochester, Minnesota

Pediatric Tumor Pathology Board - Case Discussion - Anaplastic ependymoma Rochester, Minnesota

03/2018

02/2003

02/2004

05/2005

05/2006

10/2007

04/1997

04/1998

06/1998

04/1999

04/1999

02/2001

03/2001

03/2001


Distal internal carotid artery aneurysm, intraparenchymal and subarachnoid hemorrhage - case discussion. Mortality and Morbidity Conference Department of Neurosurgery Rochester, Minnesota

Histiocytosis X of the infundibulum - Case discussion - Pediatric Tumor Board, Mayo Clinic

07/2001

04/2002

Late-infantile ceroid lipofuscinoisis - Neurology CPC 04/2002

Autopsy Brain Examination Histology Laboratory

08/2002

Choroid Plexus Carcinoma - Case Discussion - Pediatric Tumor Board 10/2002

Visiting Professorship

Visiting Professorships

Visiting Professor at University of Michigan Lecture and slide seminar University of Michigan Detroit, Michigan

03/2015

Diffuse Gliomas & The New WHO Classification Visiting Professor University of Manchester and ISPNO 2016 Manchester, United Kingdom

06/2016

Clinical Practice, Interests, and Accomplishments

Neuropathology: diagnostic surgical neuropathology with a special interest in NeuroOncology, Peripheral Nerve Pathology and autopsy neuropathology, Surgical Pathology: frozen section practice.

Research Interests Biology and pathology of peripheral nerve. Biology and pathology of primary peripheral and central nervous system neoplasms.

Research Grants Awarded

Active Grants

Federal

Co-Investigator Mechanisms of acquired temozolomide resistance in glioblastoma multiforme. Funded by National Cancer Institute. (R01 CA 176830)

04/2013 - 03/2018

Co-Investigator Impact of 18F-FDOPA-PET on neurosurgery and radiotherapy of glioma patients - Restructured - years 3-6: Impact of 18F-FDOPA-PET on neurosurgery and radiotherapy of glioma patients. Funded by National Cancer Institute. (R01 CA 178200)

07/2013 - 04/2019

Co-Investigator Integral qMS-PCR MGMT Analysis and Central Pathology Review: Alliance for Clinical Trials in Oncology Operations Center. Funded by National Cancer Institute. (U10 CA 180821)

04/2014 - 02/2019

Core Director Core C - Pathology and Tissue Procurement Core: Mayo SPORE in Brain Cancer. Funded by National Cancer Institute. (P50 CA 108961)

09/2011 - 08/2018


Completed Grants

Federal

Principal Investigator

Core B: Tissue and Pathology Component: Molecular Markers of Glioma Initiation & Progression. Funded by National Cancer Institute.

06/2001 - 05/2006

(P01 CA 85799)

Co-Investigator The North Central Cancer Treatment Group. Funded by National Cancer Institute. (U10 CA 25224-OLD)

03/2001 - 12/2006

Co-Investigator Scientific Leadership - Disease and Modality Committee Leadership: North Central Cancer Treatment Group. Funded by National Cancer Institute. (U10 CA 25224)

04/2007 - 12/2014

Co-Investigator Epigenetic regulation of temozolomide responsiveness in glioblastoma. Funded by National Cancer Institute. (R01 CA 127716)

01/2008 - 12/2012

Co-Investigator The Cancer Genome Atlas (TCGA) Pilot Program. Funded by SAIC- Frederick, Inc.. ( 28XS094)

03/2008 - 03/2013

Co-Investigator International Case-Control Study of Malignant Glioma. Funded by National Institutes of Health

03/2009 - 12/2015

Co-Investigator International Case-Control Study of Malignant Glioma. Funded by National Cancer Institute. (R01 CA 139020)

03/2010 - 12/2015

Co-Investigator Measles Virotherapy and radiovirotherapy in the Treatment of recurrent gliomas . Funded by National Cancer Institute. (R01 CA 154348)

01/2011 - 12/2016

Co-Investigator The role of a histone H4 phosphorylation in nucleosome assembly & drug resistance. Funded by National Cancer Institute. (R01 CA 157489 -01)

04/2011 - 03/2016

Co-Investigator Support to The Cancer Genome Atlas Program (TCGA). Funded by National Institutes of Health. ( 12XS460TO6)

05/2013 - 03/2014

Collaborator Xenograft Model for Studying Amplified EGFR in GBM. Funded by National Cancer Institute. (R01 NS 49720)

08/2004 - 05/2006

Collaborator The role of a histone H4 phosphorylation in drug resistance. Funded by National Cancer Institute. (R01 CA 157489)

06/2012 - 07/2016

Consultant Overcoming therapy resistance in GBM-PR05: Overcoming therapy resistance in GBM. Funded by National Cancer Institute. (R01 CA 141121)

06/2009 - 11/2014

Foundation

Co-Investigator Multiple Sclerosis Lesion Project. Funded by National Multiple Sclerosis Society. (RG3185-B-3)

04/2005 - 06/2013

Mayo Clinic

Co-Investigator Mass spectrometry based proteomic analysis of pituitary adenomas. Funded by SGP - Small Grants Program <$10K

05/2012 - 05/2014


Bibliography

Peer-reviewed Articles

1. Rossi B, Sartucci F, Giannini C, Siciliano G. Analisi delle risposte tardive del riflesso trigemino faciale. RivItal EEG e Neurofis Clin fasc 1/2/3/. 1984; 4: 201-3.

2. Rossi B, Giannini C, Siciliano G, Sartucci F. The role of the tactile-pressure afferents in the habituation phenomenon of trigemino-facial reflex. Acta Neurol Scand. 1985 Dec; 72(6):602-5. PMID: 4096201

3. Muratorio A, Rossi B, Siciliano G, Giannini C. Tecniche di valutazione EMG della fatica muscolare. Medicina dello Sport. 1986; 39:387-93.

4. Monaco S, Lucci B, Laperchia N, Tezzon F, Curro-Dossi B, Nardelli E, Giannini C, Rizzuto N. Polyneuropathy in hypereosinophilic syndrome. Neurology. 1988 Mar; 38(3):494-6. PMID: 2831471

5. Crisci C, Gomez MR, Hohberger GG, Giannini C, Dyck PJ. Is conjunctival biopsy useful for the diagnosis of neuroaxonal dystrophy. Ann Neurol. 1989; 26:691. PMID: 2486065

6. Dyck PJ, Engelstad JK, Giannini C, Lais AC, Minnerath SR, Karnes JL. Resistance to axonal degeneration after nerve compression in experimental diabetes. Proc Natl Acad Sci U S A. 1989 Mar; 86(6):2103-6. PMID: 2928319 PMCID: 286856

7. Piaggesi A, Pasca S, Giannini C, Rossi B, Giampietro O, Angelotti M, Pulitano L, Navalesi R. Neuroelectric procedure does not discriminate between painful and paresthetic diabetic neuropathy. Funct Neurol. 1989 Apr-Jun; 4(2):141-6. PMID: 2737502

8. Vitali C, Tavoni A, Rossi B, Bibolotti E, Giannini C, Puzzuoli L, Cacialli R, Pasero G. Evidence of neuromuscular hyperexcitability features in patients with primary fibromyalgia. Clin Exp Rheumatol. 1989 Jul-Aug; 7(4):385-90. PMID: 2591111

9. Giannini C, Lais AC, Dyck PJ. Number, size, and class of peripheral nerve fibers regenerating after crush, multiple crush, and graft. Brain Res. 1989 Oct 23; 500(1-2):131-8. PMID: 2605486

10. Rossi B, Vitali C, Siciliano G, Giannini C, Pingitore R. Myokymic syndrome with impaired muscular relaxation: further evidence of a possible paraneoplastic genesis. Clin Neurol Neurosurg. 1990; 92(2):169- 75. PMID: 2163802

11. Yoshikawa H, Dyck PJ, Poduslo JF, Giannini C. Polyglucosan body axonal enlargement increases myelin spiral length but not lamellar number. J Neurol Sci. 1990 Aug; 98 (1):107-17 PMID: 2230827

12. Giannini C, Dyck PJ. The fate of Schwann cell basement membranes in permanently transected nerves. Journal of Neuropathology & Experimental Neurology. 1990 Nov; 49(6):550-63. PMID: 2230836

13. Dyck PJ, Lais AC, Giannini C, Engelstad JK. Structural alterations of nerve during cuff compression. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):9828-32. PMID: 2263633 PMCID: 55267

14. Giannini C, Monaco S, Kirschfink M, Rother KO, Lorbacher de Ruiz H, Nardelli E, Bonetti B, Salviati A, Zanette GP, Rizzuto N. Inherited neuroaxonal dystrophy in C6 deficient rabbits. J Neuropathol Exp Neurol. 1992 Sep; 51(5):514-22. PMID: 1517772

15. Giannini C, Dyck PJ. Ultrastructural morphometric features of human sural nerve endoneurial microvessels. Journal of Neuropathology & Experimental Neurology. 1993 Jul; 52(4):361-9. PMID: 8355025

16. Bonetti B, Monaco S, Giannini C, Ferrari S, Zanusso G, Rizzuto N. Human peripheral nerve macrophages in normal and pathological conditions. J Neurol Sci. 1993 Sep; 118(2):158-68. PMID: 8229064

17. Suarez GA, Giannini C, Smith BE, Windebank AJ, Litchy WJ, Dyck PJ. Localized hypertrophic neuropathy. Mayo Clin Proc. 1994 Aug; 69 (8):747-8 PMID: 8035630

18. Giannini C, Dyck PJ. Ultrastructural morphometric abnormalities of sural nerve endoneurial microvessels in diabetes mellitus. Ann Neurol. 1994 Sep; 36(3):408-15. PMID: 8080248

19. Giannini C, Dyck PJ. Basement membrane reduplication and pericyte degeneration precede development of diabetic polyneuropathy and are associated with its severity. Ann Neurol. 1995 Apr; 37(4):498-504. PMID: 7717686


20. Albers JW, Anderson H, Arezzo JC, Asbury A, Bolton C, Boulton AJM, Bril V, Brown M, Brownlee M, Canal N, Chalk C, Donaghy M, Dyck PJ, Feasby T, Giannini C, Goto Y, Grant I, Greene D, Griffin J. Diabetic polyneuropathy in controlled clinical trials - consensus report of the Peripheral Nerve Society. Ann Neurol. 1995 Sep; 38:478-482. PMID: 7668839

21. Giannini C, Wright A, Dyck PJ. Polyneuropathy associated with nerve angiomatosis and multiple soft tissue tumors. A newly recognized syndrome. Am J Surg Pathol. 1995 Nov; 19(11):1325-32. PMID: 7573695

22. Passarin MG, Monaco S, Ferrari S, Giannini C, Rizzuto N, Moretto G. Cytoskeletal changes in cultured human fibroblasts following exposure to 2,5-hexanedione. Neuropathol Appl Neurobiol. 1996 Feb; 22(1):60- 7. PMID: 8866784

23. Suarez GA, Giannini C, Bosch EP, Barohn RJ, Wodak J, Ebeling P, Anderson R, McKeever PE, Bromberg MB, Dyck PJ. Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis. Neurology. 1996 Feb; 46(2):559-61. PMID: 8614534

24. Giannini C, Scheithauer BW, Wenger DE, Unni KK. Pigmented villonodular synovitis of the spine: a clinical, radiological, and morphological study of 12 cases. J Neurosurg. 1996 Apr; 84: (4)592-7. PMID: 8613850 DOI: 10.3171/jns.1996.84.4.0592

25. Giannini C. Ultrastructural morphometric analysis of human sural nerve biopsies. Diabet Med Review. 1996 Jul; 13(7):675-6.

26. Giannini C, Dyck PJ. Axoglial dysjunction: a critical appraisal of definition, techniques, and previous results. Microscopy Research & Technique. 1996 Aug 1; 34(5):436-44. PMID: 8837019

27. Dyck PJ, Giannini C. Pathologic alterations in the diabetic neuropathies of humans: a review. Journal of Neuropathology & Experimental Neurology. 1996 Dec; 55(12):1181-93. PMID: 8957441

28. Giannini C, Scheithauer BW, Jenkins RB, Erlandson RA, Perry A, Borell TJ, Hoda RS, Woodruff JM. Soft- tissue perineurioma. Evidence for an abnormality of chromosome 22, criteria for diagnosis, and review of the literature. Am J Surg Pathol. 1997 Feb; 21(2):164-73. PMID: 9042282

29. Engelstad JK, Davies JL, Giannini C, O'Brien PC, Dyck PJ. No evidence for axonal atrophy in human diabetic polyneuropathy. Journal of Neuropathology & Experimental Neurology. 1997 Mar; 56(3):255-62. PMID: 9056539

30. Giannini C, Scheithauer BW. Classification and grading of low-grade astrocytic tumors in children. Brain Pathol. 1997 Apr; 7(2):785-98. PMID: 9161729

31. Perry A, Giannini C, Scheithauer BW, Rojiani AM, Yachnis AT, Seo IS, Johnson PC, Kho J, Shapiro S. Composite pleomorphic xanthoastrocytoma and ganglioglioma: report of four cases and review of the literature. Am J Surg Pathol. 1997 Jul; 21: (7)763-71. PMID: 9236832

32. Kovacs K, Giannini C, Scheithauer BW, Stefaneanu L, Lloyd RV, Horvath E. Pituitary Changes in Ataxia- Telangiectasia Syndrome: An Immunocytochemical, In Situ Hybridization, and DNA Cytometric Study of Three Cases. Endocr Pathol. 1997 Autumn; 8(3):195-203. PMID: 12114723

33. Dal Cin P, Dei Tos AP, Qi H, Giannini C, Furlanetto A, Longatti PL, Marynen P, Van den Berghe H. Immature teratoma of the pineal gland with isochromosome 12p. Acta Neuropathol (Berl). 1998 Jan; 95: (1) 107-10. PMID: 9452829

34. Evidente VG, Adler CH, Giannini C, Conley CR, Parisi JE, Fletcher GP. Erdheim-Chester disease with extensive intraaxial brain stem lesions presenting as a progressive cerebellar syndrome. Mov Disord. 1998 May; 13(3):576-81. PMID: 9613758

35. Giannini C, Dei Tos AP. [Neuropathological diagnosis and its therapeutic implication: how to avoid excessive treatment]. Pathologica (Italian). 1998 Aug; 90: (4)408-11.

36. Giannini C, Scheithauer BW, Hellbusch LC, Rasmussen AG, Fox MW, McCormick SR, Davis DH. Peripheral nerve hemangioblastoma. Mod Pathol. 1998 Oct; 11(10):999-1004. PMID: 9796730

37. Calle-Rodrigue RD, Giannini C, Scheithauer BW, Lloyd RV, Wollan PC, Kovacs KT, Stefaneanu L, Ebright AB, Abboud CF, Davis DH. Prolactinomas in male and female patients: a comparative clinicopathologic study. Mayo Clin Proc. 1998 Nov; 73(11):1046-52. PMID: 9818037 DOI: 10.4065/73.11.1046

38. Giannini C, Scheithauer BW, Steinberg J, Cosgrove TJ. Intraventricular perineurioma: case report. Neurosurgery. 1998 Dec; 43(6):1478-81; discussion 1481-2. PMID: 9848865


39. Dei Tos AP, Dal Cin P, Sciot R, Furlanetto A, Da Mosto MC, Giannini C, Rinaldo A, Ferlito A. Synovial sarcoma of the larynx and hypopharynx. Ann Otol Rhinol Laryngol. 1998 Dec; 107(12):1080-5. PMID: 9865642

40. Giannini C, Scheithauer BW, Burger PC, Christensen MR, Wollan PC, Sebo TJ, Forsyth PA, Hayostek CJ.

Cellular proliferation in pilocytic and diffuse astrocytomas. J Neuropathol Exp Neurol. 1999 Jan; 58(1):46- 53. PMID: 10068313

41. Giannini C, Scheithauer BW, Burger PC, Brat DJ, Wollan PC, Lach B, O'Neill BP. Pleomorphic xanthoastrocytoma: what do we really know about it? Cancer. 1999 May 1; 85(9):2033-45. PMID: 10223246

42. Brat DJ, Giannini C, Scheithauer BW, Burger PC. Primary melanocytic neoplasms of the central nervous system. Am J Surg Pathol. 1999 Jul; 23(7):745-54. PMID: 10403296

43. Losi L, Buonamici L, Dal Cin P, Giannini C, Dei Tos P, Calbucci F, Eusebi V. [Cytogenetics of tumors of the central nervous system: a case study and review of the literature]. Pathologica Review Italian. 1999 Aug; 91 (4):249-55.

44. Giannini C, Di Paola F. [Brain tumors: update 6 years after the publication of the WHO blue book]. Pathologica Review Italian. 1999 Dec; 91(6):423-33.

45. Vege KD, Giannini C, Scheithauer BW. The immunophenotype of ependymomas. Appl Immunohistochem Mol Morphol. 2000 Mar; 8: (1)25-31. PMID: 10937045

46. Finckh U, Alberici A, Antoniazzi M, Benussi L, Fedi V, Giannini C, Gal A, Nitsch RM, Binetti G. Variable expression of familial Alzheimer disease associated with presenilin 2 mutation M239I. Neurology. 2000 May 23; 54(10):2006-8. PMID: 10822446

47. Giannini C, Scheithauer BW, Weaver AL, Burger PC, Kros JM, Mork S, Graeber MB, Bauserman S, Buckner JC, Burton J, Riepe R, Tazelaar HD, Nascimento AG, Crotty T, Keeney GL, Pernicone P, Altermatt H. Oligodendrogliomas: reproducibility and prognostic value of histologic diagnosis and grading. J Neuropathol Exp Neurol. 2001 Mar; 60(3):248-62. PMID: 11245209

48. Giannini C, Hebrink D, Scheithauer BW, Dei Tos AP, James CD. Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma. Neurogenetics. 2001 Jul; 3(3):159-62. PMID: 11523567

49. Perry A, Giannini C, Raghavan R, Scheithauer BW, Banerjee R, Margraf L, Bowers DC, Lytle RA, Newsham IF, Gutmann DH. Aggressive phenotypic and genotypic features in pediatric and NF2-associated meningiomas: a clinicopathologic study of 53 cases. J Neuropathol Exp Neurol. 2001 Oct; 60(10):994-1003. PMID: 11589430

50. Egensperger R, Scheithauer BW, Horvath E, Kovacs K, Giannini C, Young WF, Lloyd R, Atkinson J, Nippoldt TB. Cushing's disease due to plurihormonal adrenocorticotropic hormone and gonadotropin- producing pituitary adenoma. Acta Neuropathol. 2001 Oct; 102(4):398-403. PMID: 11603817

51. Hirose T, Giannini C, Scheithauer BW. Ultrastructural features of pleomorphic xanthoastrocytoma: a comparative study with glioblastoma multiforme. Ultrastruct Pathol. 2001 Nov-Dec; 25(6):469-78. PMID: 11783911

52. Giannini C, Scheithauer BW, Lopes MB, Hirose T, Kros JM, VandenBerg SR. Immunophenotype of pleomorphic xanthoastrocytoma. Am J Surg Pathol. 2002 Apr; 26(4):479-85. PMID: 11914626

53. Giannini C, Reynolds C, Leavitt JA, Schultz GA, Garrity JA, Ebersold MJ, Scheithauer BW, Salomao DR. Choristoma of the optic nerve: case report. Neurosurgery. 2002 May; 50(5):1125-8. PMID: 11987274

54. Maher CO, Spinner RJ, Giannini C, Scheithauer BW, Crum BA. Neuromuscular choristoma of the sciatic nerve. Case report. J Neurosurg. 2002 Jun; 96: (6)1123-6. PMID: 12066915 DOI: 10.3171/jns.2002.96.6.1123

55. Dedeurwaerdere F, Giannini C, Sciot R, Rubin BP, Perilongo G, Borghi L, Ballotta ML, Cornips E, Demunter A, Maes B, Tos APD. Primary peripheral PNET/Ewing's sarcoma of the dura: a clinicopathologic entity distinct from central PNET. Mod Pathol. 2002 Jun; 15(6):673-8. PMID: 12065782

56. Link MJ, Driscoll CLW, Giannini C. Isolated, giant cerebellopontine angle craniopharyngioma in a patient with Gardner syndrome: Case report. Neurosurgery. 2002 Jul; 51(1):221-5. PMID: 12182421


57. Achim C, Auer R, Bergeron C, Cardozo A, Deprez M, de Vos R, Duyckaerts C, Egensperger R, Esiri M, Frosch MP, Giannini C, Goebel HH, Graeber MB, Graham DI, Gray F, Haltia M, Hashizume Y, Ikeda K, Ironside JW, Kreutzberg GW, Lantos P, Lowe J, Ludwin S, Matsumoto Y, Olsson Y, Sasaki A, Scheithauer BW, Takahashi H, Tolnay M, Trojanowski JQ, Troost D, de F Webster H. Global democratic consensus on neuropathological disease criteria. Lancet Neurol. 2002 Oct; 1(6):340. PMID: 12849392

58. Pollock BE, Stafford SL, Utter A, Giannini C, Schreiner SA. Stereotactic radiosurgery provides equivalent tumor control to Simpson Grade 1 resection for patients with small- to medium-size meningiomas. Int J Radiat Oncol Biol Phys. 2003 Mar 15; 55(4):1000-5. PMID: 12605979

59. Wijdicks EFM, Manno EM, Fulgham JR, Giannini C. Cerebral angiitis mimicking posterior leukoencephalopathy. J Neurol. 2003 Apr; 250(4):444-8. PMID: 12700910

60. Cohen-Gadol AA, Pichelmann MA, Link MJ, Scheithauer BW, Krecke KN, Young WF Jr, Hardy J, Giannini C. Granular cell tumor of the sellar and suprasellar region: clinicopathologic study of 11 cases and literature review. Mayo Clin Proc. 2003 May; 78: (5)567-73. PMID: 12744543 DOI: 10.4065/78.5.567

61. Phuong LK, Allen C, Peng KW, Giannini C, Greiner S, TenEyck CJ, Mishra PK, Macura SI, Russell SJ, Galanis EC. Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme. Cancer Res. 2003 May 15; 63 (10):2462-9 PMID: 12750267

62. McWilliams RR, Giannini C, Hay ID, Atkinson JL, Stafford SL, Buckner JC. Management of brain metastases from thyroid carcinoma: a study of 16 pathologically confirmed cases over 25 years. Cancer. 2003 Jul 15; 98(2):356-62. PMID: 12872357

63. McIver JI, Link MJ, Giannini C, Cohen-Gadol AA, Driscoll C. Choroid plexus papilloma and meningioma: Coincidental posterior fossa tumors - Case report and review of the literature. Surg Neurol. 2003 Oct; 60 (4):360-5. PMID: 14505866

64. Giannini C. Gliomas of childhood. Pathologica. 2003 Oct; 95(5):237. PMID: 14988987

65. Rodriguez F, Scheithauer BW, Ockner DM, Giannini C. Solitary fibrous tumor of the cerebellopontine angle with salivary gland heterotopia: a unique presentation. Am J Surg Pathol. 2004 Jan; 28(1):139-42. PMID: 14707876

66. Chang BS, Piao X, Giannini C, Cascino GD, Scheffer I, Woods CG, Topcu M, Tezcan K, Bodell A, Leventer RJ, Barkovich AJ, Grant PE, Walsh CA. Bilateral generalized polymicrogyria (BGP) - A distinct syndrome of cortical malformation. Neurology. 2004 May 25; 62(10):1722-8. PMID: 15159468

67. Moro M, Giannini C, Scheithauer BW, Lloyd RV, Restall P, Eagleton C, Law AJ, Kovacs K. Combined sellar fibrosarcoma and prolactinoma with neuronal metaplasia: report of a case unassociated with radiotherapy. Endocr Pathol. 2004 Summer; 15 (2):149-58 PMID: 15299201

68. Aldape KD, Ballman K, Furth A, Buckner JC, Giannini C, Burger PC, Scheithauer BW, Jenkins RB, James CD. Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance. J Neuropathol Exp Neurol. 2004 Jul; 63(7):700-7. PMID: 15290895

69. Allen C, McDonald C, Giannini C, Peng KW, Rosales G, Russell SJ, Galanis E. Adenoviral vectors expressing fusogenic membrane glycoproteins activated via matrix metalloproteinase cleavable linkers have significant antitumor potential in the gene therapy of gliomas. J Gene Med. 2004 Nov; 6(11):1216-27. PMID: 15459967 DOI: 10.1002/jgm.616

70. Lee SB, Jones LK, Giannini C. Brainstem infarcts as an early manifestation of Streptococcus anginosus meningitis. Neurocrit Care. 2005; 3 (2):157-60 PMID: 16174887 DOI: 10.1385/NCC:3:2:157

71. Rodriguez F, Link MJ, Driscoll CL, Giannini C. Neurosarcoidosis mimicking meningioma. Arch Neurol. 2005 Jan; 62(1):148-9. PMID: 15642863 DOI: 10.1001/archneur.62.1.148

72. Maramattom BV, Giannini C, Manno EM, Wijdicks EF. Wegener's granulomatosis and vertebro-basilar thrombosis. Cerebrovasc Dis. 2005; 20: (1)65-8. PMID: 15980626 DOI: 10.1159/000086494

73. Giannini C, Sarkaria JN, Saito A, Uhm JH, Galanis E, Carlson BL, Schroeder MA, James CD. Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme. Neuro Oncol. 2005 Apr; 7: (2)164-76. PMID: 15831234 PMCID: 1871885 DOI: 10.1215/S1152851704000821


74. Rodriguez FJ, Crum BA, Krauss WE, Scheithauer BW, Giannini C. Venous congestive myelopathy: a mimic of neoplasia. Mod Pathol. 2005 May; 18(5):710-8. PMID: 15578073 DOI: 10.1038/modpathol.3800350

75. Tu PH, Giannini C, Judkins AR, Schwalb JM, Burack R, O'Neill BP, Yachnis AT, Burger PC, Scheithauer BW, Perry A. Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: A primary low- grade CNS lymphoma that mimics meningioma. J Clin Oncol. 2005 Aug 20; 23(24):5718-27. PMID: 16009945

76. McDonald JM, See SJ, Tremont IW, Colman H, Gilbert MR, Groves M, Burger PC, Louis DN, Giannini C,

Fuller G, Passe S, Blair H, Jenkins RB, Yang H, Ledoux A, Aaron J, Tipnis U, Zhang W, Hess K, Aldape K. The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors. Cancer. 2005 Oct 1; 104(7):1468-77. PMID: 16088966 DOI: 10.1002/cncr.21338

77. Wetjen NM, Link MJ, Reimer R, Nichols DA, Giannini C. Clinical presentation and surgical management of dissecting posterior inferior cerebellar artery aneurysms: 2 case reports. Surg Neurol. 2005 Nov; 64(5):462- 7. PMID: 16253703

78. Patrick TA, Giannini C, Ebersold MJ, Link MJ. Iatrogenic cerebellar implantation of a vestibular schwannoma. Case report. J Neurosurg. 2006 Mar; 104(3):452-6. PMID: 16572663 DOI: 10.3171/jns.2006.104.3.452

79. Sarkaria JN, Carlson BL, Schroeder MA, Grogan P, Brown PD, Giannini C, Ballman KV, Kitange GJ, Guha

A, Pandita A, James CD. Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response. Clin Cancer Res. 2006 Apr 1; 12(7 Pt 1):2264-71. PMID: 16609043 DOI: 10.1158/1078-0432.CCR-05-2510

80. Colman H, Giannini C, Huang L, Gonzalez J, Hess K, Bruner J, Fuller G, Langford L, Pelloski C, Aaron J, Burger P, Aldape K. Assessment and prognostic significance of mitotic index using the mitosis marker phospho-histone H3 in low and intermediate-grade infiltrating astrocytomas. Am J Surg Pathol. 2006 May; 30(5):657-64. PMID: 16699322 DOI: 10.1097/01.pas.0000202048.28203.25

81. Maramattom BV, Giannini C, Manno EM, Wijdicks EF, Campeau NG. Gliomatosis cerebri angiographically mimicking central nervous system angiitis: case report. Neurosurgery. 2006 Jun; 58 (6):E1209; discussion E1209 PMID: 16723870 PMCID: 0 DOI: 10.1227/01.NEU.0000216258.35308.AA

82. Krishnan S, Brown PD, Ballman KV, Fiveash JB, Uhm JH, Giannini C, Jaeckle KA, Geoffroy FJ, Nabors LB, Buckner JC, North Central Cancer Treatment Group. Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177. Int J Radiat Oncol Biol Phys. 2006 Jul 15; 65(4):1192-9. Epub 2006 Apr 19. PMID: 16626884 DOI: 10.1016/j.ijrobp.2006.01.018

83. Jenkins RB, Blair H, Ballman KV, Giannini C, Arusell RM, Law M, Flynn H, Passe S, Felten S, Brown PD, Shaw EG, Buckner JC. A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res. 2006 Oct 15; 66(20):9852-61. PMID: 17047046 DOI: 10.1158/0008-5472.CAN-06-1796

84. Boeve BF, Baker M, Dickson DW, Parisi JE, Giannini C, Josephs KA, Hutton M, Pickering-Brown SM, Rademakers R, Tang-Wai D, Jack CR Jr, Kantarci K, Shiung MM, Golde T, Smith GE, Geda YE, Knopman DS, Petersen RC. Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic study. Brain. 2006 Nov; 129 (Pt 11):3103-14 Epub 2006 Oct 09 PMID: 17030535 DOI: 10.1093/brain/awl268

85. Salvarani C, Giannini C, Miller DV, Hunder G. Giant cell arteritis: Involvement of intracranial arteries. Arthritis Rheum. 2006 Dec 15; 55(6):985-9. PMID: 17139651 DOI: 10.1002/art.22359

86. Allen C, Vongpunsawad S, Nakamura T, James CD, Schroeder M, Cattaneo R, Giannini C, Krempski J, Peng KW, Goble JM, Uhm JH, Russell SJ, Galanis E. Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity. Cancer Res. 2006 Dec 15; 66(24):11840-50. PMID: 17178881 DOI: 10.1158/0008-5472.CAN-06-1200

87. Ballman KV, Buckner JC, Brown PD, Giannini C, Flynn PJ, LaPlant BR, Jaeckle KA. The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme. Neuro Oncol. 2007 Jan; 9(1):29-38. Epub 2006 Nov 15 PMID: 17108063 PMCID: 1828103 DOI: 10.1215/15228517-2006-025


88. Sarkaria JN, Yang L, Grogan PT, Kitange GJ, Carlson BL, Schroeder MA, Galanis E, Giannini C, Wu W, Dinca EB, James CD. Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel. Mol Cancer Ther. 2007 Mar; 6 (3):1167-74. PMID: 17363510

89. Pang NK, Bartley GB, Giannini C. Primary Ewing sarcoma of the orbit in an adult. Ophthal Plast Reconstr Surg. 2007 Mar-Apr; 23(2):153-4. PMID: 17413636 DOI: 10.1097/IOP.0b013e318032e4fd

90. Leenstra JL, Rodriguez FJ, Frechette CM, Giannini C, Stafford SL, Pollock BE, Schild SE, Scheithauer BW, Jenkins RB, Buckner JC, Brown PD. Central neurocytoma: management recommendations based on a 35- year experience. Int J Radiat Oncol Biol Phys. 2007 Mar 15; 67: (4)1145-54. PMID: 17187939 DOI: 10.1016/j.ijrobp.2006.10.018

91. Kros JM, Gorlia T, Kouwenhoven MC, Zheng PP, Collins VP, Figarella-Branger D, Giangaspero F, Giannini C, Mokhtari K, Mork SJ, Paetau A, Reifenberger G, van den Bent MJ. Panel review of anaplastic oligodendroglioma from European Organization For Research and Treatment of Cancer Trial 26951: assessment of consensus in diagnosis, influence of 1p/19q loss, and correlations with outcome. J Neuropathol Exp Neurol. 2007 Jun; 66(6):545-51. PMID: 17549014 DOI: 10.1097/01.jnen.0000263869.84188.72

92. Rodriguez FJ, Eberhart C, O'Neill BP, Slezak J, Burger PC, Goldthwaite P, Wu W, Giannini C. Histopathologic grading of adult medulloblastomas. Cancer. 2007 Jun 15; 109(12):2557-65. PMID: 17487854

DOI: 10.1002/cncr.22717

93. Amador N, Scheithauer BW, Giannini C, Raffel C. Acute cerebellitis presenting as tumor. Report of two cases. J Neurosurg. 2007 Jul; 107(1 Suppl):57-61. PMID: 17644922

94. O'Neill BP, Vernino S, Dogan A, Giannini C. EBV-associated lymphoproliferative disorder of CNS associated with the use of mycophenolate mofetil. Neuro Oncol. 2007 Jul; 9: (3)364-9. PMID: 17522336 PMCID: 1907424 DOI: 10.1215/15228517-2007-004

95. Rodriguez FJ, Atkinson JL, Giannini C. Massive sellar and parasellar schwannoma. Arch Neurol. 2007 Aug; 64(8):1198-9. PMID: 17698713 DOI: 10.1001/archneur.64.8.1198

96. Kumar G, Kang CA, Giannini C. Neurosarcoidosis presenting as a cerebellar mass. J Gen Intern Med. 2007 Sep; 22(9):1373-6. Epub 2007 Jul 06. PMID: 17619108 PMCID: 2219770 DOI: 10.1007/s11606-007-0272-7

97. Buckner JC, O'Fallon JR, Dinapoli RP, Schomberg PJ, Farr G, Schaefer P, Giannini C, Scheithauer BW, Ballman KV. Prognosis in patients with anaplastic oligoastrocytoma is associated with histologic grade. J Neurooncol. 2007 Sep; 84 (3):279-86 Epub 2007 Apr 13 PMID: 17431544 DOI: 10.1007/s11060-007-9370-y

98. Schiff D, Brown PD, Giannini C. Outcome in adult low-grade glioma: the impact of prognostic factors and treatment. Neurology. 2007 Sep 25; 69(13):1366-73. PMID: 17893297 DOI: 10.1212/01.wnl.0000277271.47601.a1

99. Milligan BD, Giannini C, Link MJ. Ganglioglioma in the cerebellopontine angle in a child. Case report and review of the literature. J Neurosurg. 2007 Oct; 107(4 Suppl):292-6. PMID: 17941493

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Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Weigand SD, Miller DV, Giannini C, Meschia JF, Huston J 3rd, Hunder GG. Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol. 2007 Nov; 62(5):442-51. PMID: 17924545 DOI: 10.1002/ana.21226

Rodriguez FJ, Thibodeau SN, Jenkins RB, Schowalter KV, Caron BL, O'neill BP, James CD, Passe S, Slezak J, Giannini C. MGMT immunohistochemical expression and promoter methylation in human glioblastoma. Appl Immunohistochem Mol Morphol. 2008 Jan; 16: (1)59-65. PMID: 18091318 DOI: 10.1097/PAI.0b013e31802fac2f

Lucchetta M, Favero M, Schiavon F, Cagnin A, Manara R, Rotilio A, Orvieto E, Giannini C, Briani C. Wegener's granulomatosis confined to nervous system. BMJ Case Reports. 2008.

Foy AB, Giannini C, Raffel C. Allergic reaction to a bovine dural substitute following spinal cord untethering. Case report. J Neurosurg Pediatr. 2008 Feb; 1(2):167-9. PMID: 18352792 DOI: 10.3171/PED/2008/1/2/167

Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG. Primary central nervous system vasculitis with prominent leptomeningeal enhancement: a subset with a benign outcome. Arthritis Rheum. 2008 Feb; 58: (2)595-603. PMID: 18240248 DOI: 10.1002/art.23300


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Salvarani C, Brown RD Jr, Calamia KT, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG. Efficacy of tumor necrosis factor alpha blockade in primary central nervous system vasculitis resistant to immunosuppressive treatment. Arthritis Rheum. 2008 Feb 15; 59(2):291-6. PMID: 18240197 DOI: 10.1002/art.23337

Rodriguez FJ, Perry A, Gutmann DH, O'Neill BP, Leonard J, Bryant S, Giannini C. Gliomas in neurofibromatosis type 1: a clinicopathologic study of 100 patients. J Neuropathol Exp Neurol. 2008 Mar; 67: (3)240-9. PMID: 18344915 PMCID: 3417064 DOI: 10.1097/NEN.0b013e318165eb75

Keegan BM, Giannini C, Parisi JE, Lucchinetti CF, Boeve BF, Josephs KA. Sporadic adult-onset leukoencephalopathy with neuroaxonal spheroids mimicking cerebral MS. Neurology. 2008 Mar 25; 70(13 Pt 2):1128-33. Epub 2008 Feb 20. PMID: 18287567 DOI: 10.1212/01.wnl.0000304045.99153.8f

Porter AB, Giannini C, Kaufmann T, Lucchinetti CF, Wu W, Decker PA, Atkinson JL, O'Neill BP. Primary central nervous system lymphoma can be histologically diagnosed after previous corticosteroid use: a pilot study to determine whether corticosteroids prevent the diagnosis of primary central nervous system lymphoma. Ann Neurol. 2008 May; 63(5):662-7. PMID: 18481293 DOI: 10.1002/ana.21366

Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J, Meschia JF, Giannini C, Miller DV, Hunder GG. Primary CNS vasculitis with spinal cord involvement. Neurology. 2008 Jun 10; 70(24 Pt 2):2394-400. PMID: 18541872 DOI: 10.1212/01.wnl.0000314687.69681.24

Yang L, Clarke MJ, Carlson BL, Mladek AC, Schroeder MA, Decker P, Wu W, Kitange GJ, Grogan PT, Goble JM, Uhm J, Galanis E, Giannini C, Lane HA, James CD, Sarkaria JN. PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel. Clin Cancer Res. 2008 Jun 15; 14: (12)3993-4001. PMID: 18559622 PMCID: 3972037 DOI: 10.1158/1078-0432.CCR-07-4152

Giannini C, Burger PC, Berkey BA, Cairncross JG, Jenkins RB, Mehta M, Curran WJ, Aldape K. Anaplastic oligodendroglial tumors: refining the correlation among histopathology, 1p 19q deletion and clinical outcome in Intergroup Radiation Therapy Oncology Group Trial 9402. Brain Pathol. 2008 Jul; 18(3):360-9. Epub 2008 Mar 26. PMID: 18371182 DOI: 10.1111/j.1750-3639.2008.00129.x

Lucchinetti CF, Gavrilova RH, Metz I, Parisi JE, Scheithauer BW, Weigand S, Thomsen K, Mandrekar J, Altintas A, Erickson BJ, Konig F, Giannini C, Lassmann H, Linbo L, Pittock SJ, Bruck W. Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis. Brain. 2008 Jul; 131: (Pt 7) 1759-75. PMID: 18535080 PMCID: 2442427 DOI: 10.1093/brain/awn098

Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG. Angiography-negative primary central nervous system vasculitis: a syndrome involving small cerebral vessels. Medicine (Baltimore). 2008 Sep; 87: (5)264-71. PMID: 18794709 DOI: 10.1097/MD.0b013e31818896e1

Fealey ME, Edwards WD, Giannini C, Piepgras DG, Cloft H, Rihal CS. Complications of endovascular polymers associated with vascular introducer sheaths and metallic coils in 3 patients, with literature review. Am J Surg Pathol. 2008 Sep; 32(9):1310-6. PMID: 18636015 DOI: 10.1097/PAS.0b013e318165582a

Claassen DO, Parisi JE, Giannini C, Boeve BF, Dickson DW, Josephs KA. Frontotemporal dementia mimicking dementia with Lewy bodies. Cogn Behav Neurol. 2008 Sep; 21(3):157-63. PMID: 18797258 DOI: 10.1097/WNN.0b013e3181864a09

Allen C, Paraskevakou G, Iankov I, Giannini C, Schroeder M, Sarkaria J, Puri RK, Russell SJ, Galanis E. Interleukin-13 displaying retargeted oncolytic measles virus strains have significant activity against gliomas with improved specificity. Mol Ther. 2008 Sep; 16: (9)1556-64. PMID: 18665158 PMCID: 2748750 DOI: 10.1038/mt.2008.152

Allen C, Paraskevakou G, Iankov I, Giannini C, Schroeder M, Sarkaria J, Puri RK, Russell SJ, Galanis E. Interleukin-13 Displaying Retargeted Oncolytic Measles Virus Strains Have Significant Activity Against Gliomas With Improved Specificity. Mol Ther. 2008 Sep; 16: (9)1556-1564. PMID: 28189011 DOI: 10.1038/mt.2008.152

Van Gompel JJ, Stead SM, Giannini C, Meyer FB, Marsh WR, Fountain T, So E, Cohen-Gadol A, Lee KH, Worrell GA. Phase I trial: safety and feasibility of intracranial electroencephalography using hybrid subdural electrodes containing macro- and microelectrode arrays. Neurosurg Focus. 2008 Sep; 25: (3)E23. PMID: 18759625 PMCID: 2841515 DOI: 10.3171/FOC/2008/25/9/E23


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Rodriguez FJ, Gamez JD, Vrana JA, Theis JD, Giannini C, Scheithauer BW, Parisi JE, Lucchinetti CF, Pendlebury WW, Bergen HR, Dogan A. Immunoglobulin derived depositions in the nervous system: novel mass spectrometry application for protein characterization in formalin-fixed tissues. Lab Invest. 2008 Oct; 88 (10):1024-37. Epub 2008 Aug 18. PMID: 18711355 DOI: 10.1038/labinvest.2008.72

Cady FM, O'Neill BP, Law ME, Decker PA, Kurtz DM, Giannini C, Porter AB, Kurtin PJ, Johnston PB, Dogan A, Remstein ED. Del(6)(q22) and BCL6 rearrangements in primary CNS lymphoma are indicators of an aggressive clinical course. J Clin Oncol. 2008 Oct 10; 26(29):4814-9. Epub 2008 Jul 21. PMID: 18645192 PMCID: 2653136 DOI: 10.1200/JCO.2008.16.1455

Kleinschmidt-DeMasters BK, Damek DM, Lillehei KO, Dogan A, Giannini C. Epstein Barr virus-associated primary CNS lymphomas in elderly patients on immunosuppressive medications. J Neuropathol Exp Neurol. 2008 Nov; 67(11):1103-11. PMID: 18957891 DOI: 10.1097/NEN.0b013e31818beaea

Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG. Primary central nervous system vasculitis: comparison of patients with and without cerebral amyloid angiopathy. Rheumatology (Oxford). 2008 Nov; 47: (11)1671-7. PMID: 18753193 DOI: 10.1093/rheumatology/ken328

Porter AB, Bernold DM, Giannini C, Foote RL, Link MJ, Olsen KD, Moynihan TJ, Buckner JC. Retrospective review of adjuvant chemotherapy for esthesioneuroblastoma. J Neurooncol. 2008 Nov; 90 (2):201-4 Epub 2008 July 17 PMID: 18633576 DOI: 10.1007/s11060-008-9645-y

Rodriguez FJ, Scheithauer BW, Giannini C, Bryant SC, Jenkins RB. Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: a comparative morphologic and molecular genetic study. Cancer. 2008 Nov 15; 113: (10)2779-89. PMID: 18816605 PMCID: 2597667 DOI: 10.1002/cncr.23899

Rodriguez FJ, Giannini C, Asmann YW, Sharma MK, Perry A, Tibbetts KM, Jenkins RB, Scheithauer BW, Anant S, Jenkins S, Eberhart CG, Sarkaria JN, Gutmann DH. Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypes. J Neuropathol Exp Neurol. 2008 Dec; 67: (12)1194-204. PMID: 19018242 PMCID: 2730602 DOI: 10.1097/NEN.0b013e31818fbe1e

Brown PD, Krishnan S, Sarkaria JN, Wu W, Jaeckle KA, Uhm JH, Geoffroy FJ, Arusell R, Kitange G, Jenkins RB, Kugler JW, Morton RF, Rowland KM Jr, Mischel P, Yong WH, Scheithauer BW, Schiff D, Giannini C, Buckner JC, North Central Cancer Treatment Group Study N0177. Phase III trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177. J Clin Oncol. 2008 Dec 01; 26: (34)5603-9. PMID: 18955445 PMCID: 2651097 DOI: 10.1200/JCO.2008.18.0612

Miller DV, Salvarani C, Hunder GG, Brown RD, Parisi JE, Christianson TJ, Giannini C. Biopsy findings in primary angiitis of the central nervous system. Am J Surg Pathol. 2009 Jan; 33(1):35-43. PMID: 18941399 DOI: 10.1097/PAS.0b013e318181e097

Rodriguez FJ, Scheithauer BW, Erickson LA, Jenkins RB, Giannini C. Ectopic low-grade adrenocortical carcinoma in the spinal region: immunohistochemical and molecular cytogenetic study of a pediatric case. Am J Surg Pathol. 2009 Jan; 33: (1)142-8. PMID: 18941403 PMCID: 3427599 DOI: 10.1097/PAS.0b013e318180deda

Uhm J, Ballman K, Wu W, Giannini C, Krauss J, Buckner J, James C, Scheithauer B, Behrens R, Flynn P, Schaefer P, Dakhil S. Phase II Evaluation of Gefitinib in Patients With Newly Diagnosed Grade 4 Astrocytoma: Mayo/North Central Cancer Treatment Group study N0074 Int J Radiat Oncol Biol Phys. 2009. PMID: 0

Jicha GA, Glantz J, Clarke MJ, Lehwald LM, Russo DP, Giannini C, Wald JT, Uhm J, Kumar N, Aksamit AJ, Wetmore CJ. Primary diffuse leptomeningeal gliomatosis. Eur Neurol. 2009; 62(1):16-22. Epub 2009 May 04. PMID: 19407451 DOI: 10.1159/000216838

Josephs KA, Ahlskog JE, Parisi JE, Boeve BF, Crum BA, Giannini C, Petersen RC. Rapidly progressive neurodegenerative dementias. Arch Neurol. 2009 Feb; 66: (2)201-7. PMID: 19204156 PMCID: 2764283 DOI: 10.1001/archneurol.2008.534

Kitange GJ, Carlson BL, Mladek AC, Decker PA, Schroeder MA, Wu W, Grogan PT, Giannini C, Ballman KV, Buckner JC, James CD, Sarkaria JN. Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model. J Neurooncol. 2009 Mar; 92: (1)23- 31. PMID: 19011762 PMCID: 2790867 DOI: 10.1007/s11060-008-9737-8


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Neder L, Scheithauer BW, Turel KE, Arnesen MA, Ketterling RP, Jin L, Moynihan TJ, Giannini C, Meyer FB. Desmoplastic small round cell tumor of the central nervous system: report of two cases and review of the literature. Virchows Arch. 2009 Apr; 454 (4):431-9 Epub 2009 Mar 05 PMID: 19263077 DOI: 10.1007/s00428-009- 0750-x

Vogelbaum MA, Berkey B, Peereboom D, Macdonald D, Giannini C, Suh JH, Jenkins R, Herman J, Brown P, Blumenthal DT, Biggs C, Schultz C, Mehta M. Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. Neuro Oncol. 2009 Apr; 11(2):167-75. Epub 2008 Sep 08. PMID: 18779504

PMCID: 2718988 DOI: 10.1215/15228517-2008-073

Galanis E, Jaeckle KA, Maurer MJ, Reid JM, Ames MM, Hardwick JS, Reilly JF, Loboda A, Nebozhyn M, Fantin VR, Richon VM, Scheithauer B, Giannini C, Flynn PJ, Moore DF Jr, Zwiebel J, Buckner JC. Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study. J Clin Oncol. 2009 Apr 20; 27: (12)2052-8. PMID: 19307505 PMCID: 2669764 DOI: 10.1200/JCO.2008.19.0694

Schomas DA, Laack NN, Rao RD, Meyer FB, Shaw EG, O'Neill BP, Giannini C, Brown PD. Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro Oncol. 2009 Aug; 11: (4)437-45. PMID: 19018039 PMCID: 2743224 DOI: 10.1215/15228517-2008-102

Wrensch M, Jenkins RB, Chang JS, Yeh RF, Xiao Y, Decker PA, Ballman KV, Berger M, Buckner JC, Chang S, Giannini C, Halder C, Kollmeyer TM, Kosel ML, LaChance DH, McCoy L, O'Neill BP, Patoka J, Pico AR, Prados M, Quesenberry C, Rice T, Rynearson AL, Smirnov I, Tihan T, Wiemels J, Yang P, Wiencke JK. Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat Genet. 2009 Aug; 41(8):905-8. Epub 2009 Jul 05. PMID: 19578366 PMCID: 2923561 DOI: 10.1038/ng.408

Bell ML, Rao S, So EL, Trenerry M, Kazemi N, Stead SM, Cascino G, Marsh R, Meyer FB, Watson RE, Giannini C, Worrell GA. Epilepsy surgery outcomes in temporal lobe epilepsy with a normal MRI. Epilepsia. 2009 Sep; 50: (9)2053-60. PMID: 19389144 PMCID: 2841514 DOI: 10.1111/j.1528-1167.2009.02079.x

Carlson BL, Grogan PT, Mladek AC, Schroeder MA, Kitange GJ, Decker PA, Giannini C, Wu W, Ballman KA, James CD, Sarkaria JN. Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts. Int J Radiat Oncol Biol Phys. 2009 Sep 01; 75: (1)212-9. PMID: 19695438 PMCID: 2773462 DOI: 10.1016/j.ijrobp.2009.04.026

Drucker KL, Kitange GJ, Kollmeyer TM, Law ME, Passe S, Rynearson AL, Blair H, Soderberg CL, Morlan BW, Ballman KV, Giannini C, Jenkins RB. Characterization and gene expression profiling in glioma cell lines with deletion of chromosome 19 before and after microcell-mediated restoration of normal human chromosome 19. Genes Chromosomes Cancer. 2009 Oct; 48: (10)854-64. PMID: 19544381 PMCID: 3190979 DOI: 10.1002/gcc.20688

Rodriguez FJ, Mota RA, Scheithauer BW, Giannini C, Blair H, New KC, Wu KJ, Dickson DW, Jenkins RB. Interphase cytogenetics for 1p19q and t(1;19)(q10;p10) may distinguish prognostically relevant subgroups in extraventricular neurocytoma. Brain Pathol. 2009 Oct; 19: (4)623-9. PMID: 18710393 PMCID: 2742575 DOI: 10.1111/j.1750-3639.2008.00206.x

Rossi S, Rodriguez FJ, Mota RA, Dei Tos, Di Paola, Bendini M, Agostini S, Longatti P, Jenkins RB, Giannini C. Primary leptomeningeal oligodendroglioma with documented progression to anaplasia and t (1;19)(q10;p10) in a child. Acta Neuropathol. 2009 Oct; 118(4):575-7. Epub 2009 Jun 27. PMID: 19562354 DOI: 10.1007/s00401-009-0565-5

Rodriguez FJ, Scheithauer BW, Burger PC, Jenkins S, Giannini C. Anaplasia in pilocytic astrocytoma predicts aggressive behavior. Am J Surg Pathol. 2010 Feb; 34: (2)147-60. PMID: 20061938 DOI: 10.1097/PAS.0b013e3181c75238

Abou Zeid NE, Burns JD, Wijdicks EF, Giannini C, Keegan BM. Atypical acute hemorrhagic leukoencephalitis (Hurst's disease) presenting with focal hemorrhagic brainstem lesion. Neurocrit Care. 2010 Feb; 12 (1):95-7 PMID: 19847676 DOI: 10.1007/s12028-009-9293-x

Sukov WR, Cheville JC, Giannini C, Carlson AW, Shearer BM, Sinnwell JP, Ketterling RP. Isochromosome 12p and polysomy 12 in primary central nervous system germ cell tumors: frequency and association with clinicopathologic features. Hum Pathol. 2010 Feb; 41(2):232-8. Epub 2009 Oct 03. PMID: 19801160 DOI: 10.1016/j.humpath.2009.07.017


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Young NP, Weinshenker BG, Parisi JE, Scheithauer B, Giannini C, Roemer SF, Thomsen KM, Mandrekar JN, Erickson BJ, Lucchinetti CF. Perivenous demyelination: association with clinically defined acute disseminated encephalomyelitis and comparison with pathologically confirmed multiple sclerosis. Brain. 2010 Feb; 133: (Pt 2)333-48. PMID: 20129932 PMCID: 2822631 DOI: 10.1093/brain/awp321

Rodriguez FJ, Giannini C. Oligodendroglial tumors: diagnostic and molecular pathology. Semin Diagn Pathol. 2010 May; 27(2):136-45. PMID: 20860317

Pasol J, Sternau L, Luetmer P, Giannini C. Rapid progressive unilateral visual loss in an elderly man. J Neuroophthalmol. 2010 Jun; 30(2):188-92. PMID: 20523195 DOI: 10.1097/WNO.0b013e3181e1f85c

Bower RS, Burrus TM, Giannini C, Erickson BJ, Meyer FB, Pirko I, Mauermann ML. Teaching NeuroImages: demyelinating disease mimicking butterfly high-grade glioma. Neurology. 2010 Jul 13; 75: (2) e4-5. PMID: 20625159 PMCID: 2923494 DOI: 10.1212/WNL.0b013e3181e7ca1b

Jaeckle KA, Ballman KV, Giannini C, Schomberg PJ, Ames MM, Reid JM, McGovern RM, Safgren SL, Galanis E, Uhm JH, Brown PD, Hammack JE, Arusell R, Nikcevich DA, Morton RF, Wender DB, Buckner JC. Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM. J Neurooncol. 2010 Aug; 99 (1):73-80 Epub 2010 Jan 09 PMID: 20063115 PMCID: 2897141 DOI: 10.1007/s11060- 009-0103-2

Rao AA, Laack NN, Giannini C, Wetmore C. Pleomorphic xanthoastrocytoma in children and adolescents. Pediatr Blood Cancer. 2010 Aug; 55(2):290-4. PMID: 20582976 DOI: 10.1002/pbc.22490

Chacko J, Brock W, Brown H, Luetmer P, Giannini C. Blurred vision and eye pain in a middle-aged woman. J Neuroophthalmol. 2010 Sep; 30(3):284-7. PMID: 20818207 DOI: 10.1097/WNO.0b013e3181ecdc45

Pittock SJ, Debruyne J, Krecke KN, Giannini C, van den Ameele J, De Herdt V, McKeon A, Fealey RD, Weinshenker BG, Aksamit AJ, Krueger BR, Shuster EA, Keegan BM. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain. 2010 Sep; 133(9):2626- 34. Epub 2010 Jul 17. PMID: 20639547 DOI: 10.1093/brain/awq164

Lopez JI, Scheithauer BW, Giannini C, Torp SH. Concurrent solitary fibrous tumor and low-grade fibrillary astrocytoma of the cerebellum. Clin Neuropathol. 2010 Sep-Oct; 29(5):301-6. PMID: 20860893

Lewis-Tuffin LJ, Rodriguez F, Giannini C, Scheithauer B, Necela BM, Sarkaria JN, Anastasiadis PZ. Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype. PLoS One. 2010 Oct 27; 5: (10)e13665. PMID: 21060868 PMCID: 2965143 DOI: 10.1371/journal.pone.0013665

Kitange GJ, Carlson BL, Schroeder MA, Decker PA, Morlan BW, Wu W, Ballman KV, Giannini C, Sarkaria JN. Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance. J Neurooncol. 2010 Nov; 100: (2)177-86. PMID: 20443131 PMCID: 3233976 DOI: 10.1007/s11060-010-0186-9

Sarkaria JN, Galanis E, Wu W, Dietz AB, Kaufmann TJ, Gustafson MP, Brown PD, Uhm JH, Rao RD, Doyle L, Giannini C, Jaeckle KA, Buckner JC. Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks. Clin Cancer Res. 2010 Nov 15; 16: (22)5573-80. PMID: 20921209 PMCID: 2982871 DOI: 10.1158/1078-0432.CCR-10-1453

Vaphiades MS, Gupta S, Palmer CA, Luetmer P, Giannini C. Progressive bilateral visual and hearing loss in an elderly woman. J Neuroophthalmol. 2010 Dec; 30(4):372-5. PMID: 21107125 DOI: 10.1097/WNO.0b013e3181f50ba2

Jenkins RB, Wrensch MR, Johnson D, Fridley BL, Decker PA, Xiao Y, Kollmeyer TM, Rynearson AL, Fink S, Rice T, McCoy LS, Halder C, Kosel ML, Giannini C, Tihan T, O'Neill BP, Lachance DH, Yang P, Wiemels J, Wiencke JK. Distinct germ line polymorphisms underlie glioma morphologic heterogeneity. Cancer Genet. 2011 Jan; 204: (1)13-8. PMID: 21356187 PMCID: 3062955 DOI: 10.1016/j.cancergencyto.2010.10.002

Ball BG, Wetmore C, Giannini C, Wetjen NM, Meyer FB. Opticochiasmatic apoplexy in a five-year-old. Pediatr Neurosurg. 2011; 47(4):279-83. Epub 2012 Mar 23. PMID: 22456272 DOI: 10.1159/000334309

Jentoft M, Giannini C, Cen L, Scheithauer BW, Hoesley B, Sarkaria JN, Abell-Aleff PC, Rodriguez EF, Li Y, Rodriguez FJ. Phenotypic variations in NF1-associated low grade astrocytomas: possible role for increased mTOR activation in a subset. Int J Clin Exp Pathol. 2011; 4(1):43-57.

Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG. Rapidly progressive primary central nervous system vasculitis. Rheumatology (Oxford). 2011 Feb; 50: (2)349-58. PMID: 20959356 DOI: 10.1093/rheumatology/keq303


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Puffer RC, Daniels DJ, Giannini C, Pichelmann MA, Rose PS, Clarke MJ. Synovial sarcoma of the spine: A report of three cases and review of the literature. Surg Neurol Int. 2011 Feb 21; 2: 18. PMID: 21394244 PMCID: 3052469 DOI: 10.4103/2152-7806.76939

Alzaga Fernandez AG, Shirka R, Skarf B, Silver B, Matloob SJ, Ober MD, Luetmer P, Giannini C. Bilateral simultaneous central retinal vein occlusions in an otherwise healthy adult. J Neuroophthalmol. 2011 Mar; 31 (1):78-82. PMID: 21317733 DOI: 10.1097/WNO.0b013e31820d0a34

Giannini C, Oelkers MM, Edwards WD, Aubry MC, Muncil MM, Mohamud KH, Sandleback SG, Nowak JM, Bridgeman A, Brown ME, Cheville JC. Maintaining clinical tissue archives and supporting human research: challenges and solutions. Arch Pathol Lab Med. 2011 Mar; 135(3):347-53. PMID: 21366459 DOI: 10.1043/2010- 0044-SA.1

Rodriguez EF, Scheithauer BW, Giannini C, Rynearson A, Cen L, Hoesley B, Gilmer-Flynn H, Sarkaria JN, Jenkins S, Long J, Rodriguez FJ. PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma. Acta Neuropathol. 2011 Mar; 121: (3)407-20. PMID: 21113787 PMCID: 3417062 DOI: 10.1007/s00401-010-0784-9

Schmitt WR, Carlson ML, Giannini C, Driscoll CL, Link MJ. Radiation-induced sarcoma in a large vestibular schwannoma following stereotactic radiosurgery: case report. Neurosurgery. 2011 Mar; 68(3):E840-6; discussion E846. PMID: 21209595 DOI: 10.1227/NEU.0b013e31820780b1

Van Gompel JJ, Koeller KK, Meyer FB, Marsh WR, Burger PC, Roncaroli F, Worrell GA, Giannini C. Cortical ependymoma: an unusual epileptogenic lesion. J Neurosurg. 2011 Apr; 114: (4)1187-94. PMID:

21235315 PMCID: 3271434 DOI: 10.3171/2010.12.JNS10846

Johnson DR, Kimmel DW, Burch PA, Cascino TL, Giannini C, Wu W, Buckner JC. Phase II study of subcutaneous octreotide in adults with recurrent or progressive meningioma and meningeal hemangiopericytoma. Neuro Oncol. 2011 May; 13: (5)530-5. PMID: 21558077 PMCID: 3093340 DOI: 10.1093/neuonc/nor044

Bernardo MC, Graff Radford J, Menke J, Hallemeier C, Boes CJ, Lewis M, Scheithauer B, Giannini C. Intravascular mucinosis: a rare cause of cerebral infarction. Acta Neuropathol 2011 Jun; 121 (6):785-8 Epub 2011 May 04 PMID: 21541761 DOI: 10.1007/s00401-011-0829-8

Hasselblatt M, Gesk S, Oyen F, Rossi S, Viscardi E, Giangaspero F, Giannini C, Judkins AR, Fruhwald MC, Obser T, Schneppenheim R, Siebert R, Paulus W. Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression. Am J Surg Pathol. 2011 Jun; 35(6):933-5. PMID: 21566516 DOI: 10.1097/PAS.0b013e3182196a39

Jentoft M, Giannini C, Rossi S, Mota R, Jenkins RB, Rodriguez FJ. Oligodendroglial tumors with marked desmoplasia: clinicopathologic and molecular features of 7 cases. Am J Surg Pathol. 2011 Jun; 35(6):845- 52. PMID: 21552114 DOI: 10.1097/PAS.0b013e3182189693

Uhm JH, Ballman KV, Wu W, Giannini C, Krauss JC, Buckner JC, James CD, Scheithauer BW, Behrens RJ, Flynn PJ, Schaefer PL, Dakhill SR, Jaeckle KA. Phase II evaluation of gefitinib in patients with newly diagnosed Grade 4 astrocytoma: Mayo/North Central Cancer Treatment Group Study N0074. Int J Radiat Oncol Biol Phys. 2011 Jun 1; 80 (2):347-53 Epub 2010 May 25 PMID: 20510539 PMCID: 5753591 DOI: 10.1016/j.ijrobp.2010.01.070

Braggio E, McPhail ER, Macon W, Lopes MB, Schiff D, Law M, Fink S, Sprau D, Giannini C, Dogan A, Fonseca R, O'Neill BP. Primary central nervous system lymphomas: a validation study of array-based comparative genomic hybridization in formalin-fixed paraffin-embedded tumor specimens. Clin Cancer Res. 2011 Jul 01; 17: (13)4245-53. PMID: 21562036 PMCID: 3131452 DOI: 10.1158/1078-0432.CCR-11-0395

Jaeckle KA, Decker PA, Ballman KV, Flynn PJ, Giannini C, Scheithauer BW, Jenkins RB, Buckner JC. Transformation of low grade glioma and correlation with outcome: an NCCTG database analysis. J Neurooncol. 2011 Aug; 104 (1):253-9 Epub 2010 Dec 12 PMID: 21153680 PMCID: 5738240 DOI: 10.1007/s11060- 010-0476-2

Flanagan EP, Hunderfund AL, Giannini C, Meissner I. Addition of magnetic resonance imaging to computed tomography and sensitivity to blood in pituitary apoplexy. Arch Neurol. 2011 Oct; 68: (10)1336-7. PMID: 21987552 DOI: 10.1001/archneurol.2011.247


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Sarkaria JN, Galanis E, Wu W, Peller PJ, Giannini C, Brown PD, Uhm JH, McGraw S, Jaeckle KA, Buckner JC. North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2011 Oct 01; 81: (2)468-75. PMID: 20864273 PMCID: 3010479 DOI: 10.1016/j.ijrobp.2010.05.064

Salvarani C, Brown RD Jr, Calamia KT, Christianson TJ, Huston J 3rd, Meschia JF, Giannini C, Miller DV, Hunder GG. Primary central nervous system vasculitis presenting with intracranial hemorrhage. Arthritis Rheum. 2011 Nov; 63: (11)3598-606. PMID: 22038406 DOI: 10.1002/art.30594

Fuehrer NE, Hammack JE, Morris JM, Kaufmann TJ, Giannini C. Teaching NeuroImages: granulomatous angiitis of the CNS associated with Hodgkin lymphoma. Neurology. 2011 Nov 8; 77(19):e110-1. PMID: 22067969 DOI: 10.1212/WNL.0b013e318236eefb

Lucchinetti CF, Popescu BF, Bunyan RF, Moll NM, Roemer SF, Lassmann H, Bruck W, Parisi JE, Scheithauer BW, Giannini C, Weigand SD, Mandrekar J, Ransohoff RM. Inflammatory cortical demyelination in early multiple sclerosis. N Engl J Med. 2011 Dec 08; 365: (23)2188-97. PMID: 22150037 PMCID: 3282172 DOI: 10.1056/NEJMoa1100648

Corradi D, Alquati S, Bertoni F, Bartoli V, Dei Tos, Wenger D, Giannini C. A small intraneural epithelioid malignant peripheral nerve sheath tumour of the median nerve simulating a benign lesion: description of a case and review of the literature. Pathol Oncol Res. 2012 Jan; 18(1):101-6. Epub 2011 Jan 1. PMID: 21197591 DOI: 10.1007/s12253-010-9348-5

Rodriguez FJ, Giannini C. Diagnostic neuropathology of tumors of the central nervous system. Handb Clin Neurol. 2012; 104:77-107. PMID: 22230437 DOI: 10.1016/B978-0-444-52138-5.00007-4

Bower RS, Daugherty WP, Giannini C, Parney IF. Intracranial phosphaturic mesenchymal tumor, mixed connective tissue variant presenting without oncogenic osteomalacia. Surg Neurol Int. 2012; 3:151. PMID: 23372968 PMCID: 3551505 DOI: 10.4103/2152-7806.104745

Hoover JM, Kumar R, Bledsoe JM, Giannini C, Krauss WE. Intramedullary melanotic schwannoma. Rare Tumors. 2012; 4(1):7-10.

Zakaria T, Noe K, So E, Cascino GD, Wetjen N, Van Gompel JJ, Marsh WR, Meyer FB, Giannini C, Watson RE, Worrell GA. Scalp and intracranial EEG in medically intractable extratemporal epilepsy with normal MRI. ISRN Neurol. 2012; 2012:942849. PMID: 22792484 PMCID: 3389725 DOI: 10.5402/2012/942849

Sedney CL, Morris JM, Giannini C, Link MJ, Swetz KM. Radiation-associated sarcoma of the skull base after irradiation for pituitary adenoma. Rare Tumors. 2012 Jan 2; 4(1):e7 Epub 2012 Jan 30. PMID: 22532923 PMCID: 3325752 DOI: 10.4081/rt.2012.e7

Friday BB, Anderson SK, Buckner J, Yu C, Giannini C, Geoffroy F, Schwerkoske J, Mazurczak M, Gross H, Pajon E, Jaeckle K, Galanis E. Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study. Neuro Oncol. 2012 Feb; 14(2):215-21. Epub 2011 Nov 16. PMID: 22090453 PMCID: 3266383 DOI: 10.1093/neuonc/nor198

Ball BG, Luetmer PH, Giannini C, Mokri B, Kumar N, Piepgras DG. Ventral "spinal epidural meningeal cysts"--not epidural and not cysts? Case series and review of the literature. Neurosurgery. 2012 Feb; 70 (2):320-8; discussion 328. PMID: 21822155 DOI: 10.1227/NEU.0b013e318230968c

Giannini C. In memoriam: Bernd Walter Scheithauer (1946-2011). Acta Neuropathol. 2012 Mar; 123(3):461 -2. PMID: 0 DOI: 10.1007/s00401-011-0917-9

Rodriguez FJ, Folpe AL, Giannini C, Perry A. Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathol. 2012 Mar; 123: (3)295-319. PMID: 22327363 PMCID: 3629555 DOI: 10.1007/s00401-012-0954-z

Schiff D, Lam EM, Parisi JE, Giannini C, Uhm JH, Keegan BM, Kantarci OH. A 21-year-old woman with multiple cancers and a new brain lesion. Neurology. 2012 Mar 6; 78(10):743-9. PMID: 22391604 DOI: 10.1212/WNL.0b013e318248e59c

Scarisbrick IA, Radulovic M, Burda JE, Larson N, Blaber SI, Giannini C, Blaber M, Vandell AG. Kallikrein 6 is a novel molecular trigger of reactive astrogliosis. Biol Chem. 2012 Apr; 393: (5)355-67. PMID: 22505518 PMCID: 3335747 DOI: 10.1515/hsz-2011-0241

Abou Zeid N, Pirko I, Erickson B, Weigand SD, Thomsen KM, Scheithauer B, Parisi JE, Giannini C, Linbo L, Lucchinetti CF. Diffusion-weighted imaging characteristics of biopsy-proven demyelinating brain lesions. Neurology. 2012 May 22; 78: (21)1655-62. PMID: 22573639 PMCID: 3359505 DOI: 10.1212/WNL.0b013e3182574f66


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Giannini C, Salvarani C, Hunder G, Brown RD. Primary central nervous system vasculitis: pathology and mechanisms. Acta Neuropathol. 2012 Jun; 123(6):759-72. Epub 2012 Mar 16. PMID: 22421812 DOI: 10.1007/s00401-012-0973-9

Ida CM, Lambert SR, Rodriguez FJ, Voss JS, Mc Cann, Seys AR, Halling KC, Collins VP, Giannini C. BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern. J Neuropathol Exp Neurol. 2012 Jul; 71(7):631-9. PMID: 22710963 DOI: 10.1097/NEN.0b013e31825c448a

Jenkins RB, Xiao Y, Sicotte H, Decker PA, Kollmeyer TM, Hansen HM, Kosel ML, Zheng S, Walsh KM, Rice T, Bracci P, McCoy LS, Smirnov I, Patoka JS, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, Chang SM, Berger MS, Caron AA, Fink SR, Halder C, Rynearson AL, Fridley BL, Buckner JC, O'Neill BP, Giannini C, Lachance DH, Wiencke JK, Eckel-Passow JE, Wrensch MR. A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet. 2012 Oct; 44: (10)1122-5. PMID: 22922872 PMCID: 3600846 DOI: 10.1038/ng.2388

Van Gompel JJ, Giannini C, Olsen KD, Moore E, Piccirilli M, Foote RL, Buckner JC, Link MJ. Long-term outcome of esthesioneuroblastoma: hyams grade predicts patient survival. J Neurol Surg B Skull Base. 2012 Oct; 73: (5)331-6. PMID: 24083125 PMCID: 3578642 DOI: 10.1055/s-0032-1321512

Compton JJ, Laack NN, Eckel LJ, Schomas DA, Giannini C, Meyer FB. Long-term outcomes for low-grade intracranial ganglioglioma: 30-year experience from the Mayo Clinic. J Neurosurg. 2012 Nov; 117: (5)825- 30. PMID: 22957524 DOI: 10.3171/2012.7.JNS111260

Ho CY, Bar E, Giannini C, Marchionni L, Karajannis MA, Zagzag D, Gutmann DH, Eberhart CG, Rodriguez FJ. MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2. Neuro Oncol. 2013 Jan; 15(1):69-82. Epub 2012 Nov 15. PMID: 23161775 PMCID: 3534421 DOI: 10.1093/neuonc/nos269

Huveldt D, Lewis-Tuffin LJ, Carlson BL, Schroeder MA, Rodriguez F, Giannini C, Galanis E, Sarkaria JN, Anastasiadis PZ. Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasion. PLoS One. 2013; 8: (2)e56505. PMID: 23457577 PMCID: 3572988 DOI: 10.1371/journal.pone.0056505

Youland RS, Kitange GJ, Peterson TE, Pafundi DH, Ramiscal JA, Pokorny JL, Giannini C, Laack NN, Parney IF, Lowe VJ, Brinkmann DH, Sarkaria JN. The role of LAT1 in (18)F-DOPA uptake in malignant gliomas. J Neurooncol. 2013 Jan; 111: (1)11-8. PMID: 23086431 PMCID: 3907171 DOI: 10.1007/s11060-012-0986-1

Drucker KL, Paulsen AR, Giannini C, Decker PA, Blaber SI, Blaber M, Uhm JH, O'Neill BP, Jenkins RB, Scarisbrick IA. Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma. Neuro Oncol. 2013 Mar; 15: (3)305-18. PMID: 23307575 PMCID: 3578488 DOI: 10.1093/neuonc/nos313

Mallory GW, Fang S, Giannini C, Van Gompel JJ, Parney IF. Brain carcinoid metastases: outcomes and prognostic factors. J Neurosurg. 2013 Apr; 118(4):889-95. Epub 2013 Feb 08. PMID: 23394337 DOI: 10.3171/2013.1.JNS121556

Chen S, Tanaka S, Giannini C, Morris J, Yan ES, Buckner J, Lachance DH, Parney IF. Gliomatosis cerebri: clinical characteristics, management, and outcomes. J Neurooncol. 2013 Apr; 112: (2)267-75. PMID: 23341100 PMCID: 3907195 DOI: 10.1007/s11060-013-1058-x

van den Bent MJ, Hartmann C, Preusser M, Strobel T, Dubbink HJ, Kros JM, von Deimling A, Boisselier B, Sanson M, Halling KC, Diefes KL, Aldape K, Giannini C. Interlaboratory comparison of IDH mutation detection. J Neurooncol. 2013 Apr; 112(2):173-8. Epub 2013 Jan 29. PMID: 23358936 DOI: 10.1007/s11060-013- 1056-z

Rykken JB, Diehn FE, Hunt CH, Eckel LJ, Schwartz KM, Kaufmann TJ, Wald JT, Giannini C, Wood CP. Rim and flame signs: postgadolinium MRI findings specific for non-CNS intramedullary spinal cord metastases. AJNR Am J Neuroradiol. 2013 Apr; 34(4):908-15. Epub 2012 Oct 18. PMID: 23079405 DOI: 10.3174/ajnr.A3292

Rice T, Zheng S, Decker PA, Walsh KM, Bracci P, Xiao Y, McCoy LS, Smirnov I, Patoka JS, Hansen HM, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, Chang SM, Berger MS, Caron A, Fink S, Kollmeyer T, Rynearson A, Voss J, Kosel ML, Fridley BL, Lachance DH, Eckel-Passow JE, Sicotte H, O'Neill BP, Giannini C, Wiencke JK, Jenkins RB, Wrensch MR. Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. Neuro Oncol. 2013 May; 15(5):535-41. Epub 2013 Jan 29. PMID: 23361564 PMCID: 3635511 DOI: 10.1093/neuonc/nos324


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Ida CM, Vrana JA, Rodriguez FJ, Jentoft ME, Caron AA, Jenkins SM, Giannini C. Immunohistochemistry is highly sensitive and specific for detection of BRAF V600E mutation in pleomorphic xanthoastrocytoma. Acta Neuropathol Commun. 2013 May 30; 1:20. PMID: 24252190 PMCID: 3893490 DOI: 10.1186/2051-5960-1-20

Leep Hunderfund AN, Zabad RK, Aksamit AJ, Morris JM, Meyer FB, Thorell WE, Parisi JE, Giannini C. Diffuse anaplastic leptomeningeal oligodendrogliomatosis mimicking neurosarcoidosis. Neurol Clin Pract. 2013 Jun; 3: (3)261-265. PMID: 23914328 PMCID: 3721246 DOI: 10.1212/CPJ.0b013e318296f23d

Cen L, Carlson BL, Pokorny JL, Mladek AC, Grogan PT, Schroeder MA, Decker PA, Anderson SK, Giannini C, Wu W, Ballman KV, Kitange GJ, Sarkaria JN. Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models. Neuro Oncol. 2013 Jun; 15: (6)735-46. PMID: 23479134 PMCID: 3661094 DOI: 10.1093/neuonc/not010

Sathananthan M, Sathananthan A, Scheithauer BW, Giannini C, Meyer FB, Atkinson JL, Erickson D. Sellar meningiomas: an endocrinologic perspective. Pituitary. 2013 Jun; 16(2):182-8. PMID: 22644157 DOI: 10.1007/s11102-012-0399-3

Takahashi R, Giannini C, Sarkaria JN, Schroeder M, Rogers J, Mastroeni D, Scrable H. p53 isoform profiling in glioblastoma and injured brain. Oncogene. 2013 Jun 27; 32: (26)3165-74. PMID: 22824800 PMCID:

3904233 DOI: 10.1038/onc.2012.322

Pafundi DH, Laack NN, Youland RS, Parney IF, Lowe VJ, Giannini C, Kemp BJ, Grams MP, Morris JM, Hoover JM, Hu LS, Sarkaria JN, Brinkmann DH. Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study. Neuro Oncol. 2013 Aug; 15: (8)1058-67. PMID: 23460322 PMCID: 3714146 DOI: 10.1093/neuonc/not002

Youland RS, Schomas DA, Brown PD, Nwachukwu C, Buckner JC, Giannini C, Parney IF, Laack NN. Changes in presentation, treatment, and outcomes of adult low-grade gliomas over the past fifty years. Neuro Oncol. 2013 Aug; 15: (8)1102-10. PMID: 23814262 PMCID: 3714159 DOI: 10.1093/neuonc/not080

Noe K, Sulc V, Wong-Kisiel L, Wirrell E, Van Gompel JJ, Wetjen N, Britton J, So E, Cascino GD, Marsh WR, Meyer F, Horinek D, Giannini C, Watson R, Brinkmann BH, Stead M, Worrell GA. Long-term outcomes after nonlesional extratemporal lobe epilepsy surgery. JAMA Neurol. 2013 Aug; 70: (8)1003-8. PMID: 23732844

PMCID: 3920594 DOI: 10.1001/jamaneurol.2013.209

Galanis E, Anderson SK, Lafky JM, Uhm JH, Giannini C, Kumar SK, Kimlinger TK, Northfelt DW, Flynn PJ, Jaeckle KA, Kaufmann TJ, Buckner JC. Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): a north central cancer treatment group trial. Clin Cancer Res. 2013 Sep 01; 19: (17)4816-23. PMID: 23833308 PMCID: 3869574 DOI: 10.1158/1078-0432.CCR-13-0708

Salvarani C, Hunder GG, Morris JM, Brown RD Jr, Christianson T, Giannini C. Abeta-related angiitis: comparison with CAA without inflammation and primary CNS vasculitis. Neurology. 2013 Oct 29; 81: (18) 1596-603. PMID: 24078731 PMCID: 3806912 DOI: 10.1212/WNL.0b013e3182a9f545

Child ND, Braksick SA, Flanagan EP, Keegan BM, Giannini C, Kantarci OH. Amyloid-beta-related angiitis presenting as a uveomeningeal syndrome. Neurology. 2013 Nov 12; 81: (20)1796-8. PMID: 24132378 DOI: 10.1212/01.wnl.0000435560.00234.a7

Youland RS, Brown PD, Giannini C, Parney IF, Uhm JH, Laack NN. Adult low-grade glioma: 19-year experience at a single institution. Am J Clin Oncol. 2013 Dec; 36: (6)612-9. PMID: 22892428 PMCID: 4361933 DOI: 10.1097/COC.0b013e31825d580a

Ida CM, Vrana JA, Rodriguez FJ, Jentoft ME, Caron AA, Jenkins SM, Giannini C. Immunohistochemistry is highly sensitive and specific for detection of BRAF V600E mutation in pleomorphic xanthoastrocytoma Acta Neuropathologica Communications. 2014; 2: (1)20.

Wijdicks EF, Giannini C. Wrong side dilated pupil. Neurology. 2014 Jan 14; 82(2):187. PMID: 24419978 DOI: 10.1212/WNL.0000000000000025

Call JA, Naik M, Rodriguez FJ, Giannini C, Wu W, Buckner JC, Parney IF, Laack NN. Long-term outcomes and role of chemotherapy in adults with newly diagnosed medulloblastoma. Am J Clin Oncol. 2014 Feb; 37: (1)1-7. PMID: 23111362 PMCID: 4361934 DOI: 10.1097/COC.0b013e31826b9cf0

Mahan MA, Shin AY, Bishop AT, Giannini C, Spinner RJ. Traumatic intraneural bone fracture fragment. J Surg Orthop Adv. 2014 Spring; 23(1):45-8. PMID: 24641897


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Cairncross JG, Wang M, Jenkins RB, Shaw EG, Giannini C, Brachman DG, Buckner JC, Fink KL, Souhami L, Laperriere NJ, Huse JT, Mehta MP, Curran WJ Jr. Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH. J Clin Oncol. 2014 Mar 10; 32 (8):783-90 Epub 2014 Feb 10 PMID: 24516018 PMCID: 3940537 DOI: 10.1200/JCO.2013.49.3726

Nozile-Firth K, Wirrell E, Giannini C. Bizarre semiology and medically intractable seizures. Semin Pediatr Neurol. 2014 Jun; 21: (2)154-9. PMID: 25149953 DOI: 10.1016/j.spen.2014.04.024

Giannini C, Dogan A, Salomao DR. CNS lymphoma: a practical diagnostic approach. J Neuropathol Exp Neurol. 2014 Jun; 73(6):478-94. PMID: 24806301 DOI: 10.1097/NEN.0000000000000076

Burkholder DB, Sulc V, Hoffman EM, Cascino GD, Britton JW, So EL, Marsh WR, Meyer FB, Van Gompel JJ, Giannini C, Wass CT, Watson RE Jr, Worrell GA. Interictal scalp electroencephalography and intraoperative electrocorticography in magnetic resonance imaging-negative temporal lobe epilepsy surgery. JAMA Neurol. 2014 Jun; 71: (6)702-9. PMID: 24781216 PMCID: 4183227 DOI: 10.1001/jamaneurol.2014.585

Flanagan EP, Krecke KN, Marsh RW, Giannini C, Keegan BM, Weinshenker BG. Specific pattern of gadolinium enhancement in spondylotic myelopathy. Ann Neurol. 2014 Jul; 76: (1)54-65. PMID: 24838831 DOI: 10.1002/ana.24184

Halling G, Giannini C, Britton JW, Lee RW, Watson RE Jr, Terrell CL, Parney IF, Buckingham EM, Carpenter JE, Grose C. Focal encephalitis following varicella-zoster virus reactivation without rash in a healthy immunized young adult. J Infect Dis. 2014 Sep 01; 210: (5)713-6. PMID: 24604820 PMCID: 4202304 DOI: 10.1093/infdis/jiu137

Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, Aldape K, Brat D, Collins VP, Eberhart C, Figarella-Branger D, Fuller GN, Giangaspero F, Giannini C, Hawkins C, Kleihues P, Korshunov A, Kros JM, Lopes MB, Ng HK, Ohgaki H, Paulus W, Pietsch T, Rosenblum M, Rushing E, Soylemezoglu F, Wiestler O, Wesseling P. International society of neuropathology-haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathol. 2014 Sep; 24(5):429-35. PMID: 24990071

Kizilbash SH, Giannini C, Voss JS, Decker PA, Jenkins RB, Hardie J, Laack NN, Parney IF, Uhm JH, Buckner JC. The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma. J Neurooncol. 2014 Oct; 120: (1)85-93. PMID: 24993250 PMCID: 4229369 DOI: 10.1007/s11060-014-1520-4

Oldenburg MS, Carlson ML, Van Abel KM, Giannini C, Jacob J, Rivas A, Driscoll CL, Link MJ. Cavernous hemangiomas of the internal auditory canal and cerebellopontine angle. Otol Neurotol. 2015 Jan; 36(1):e30- 4. PMID: 25105799 DOI: 10.1097/MAO.0000000000000519

Brinjikji W, Morris JM, Brown RD, Thielen KR, Wald JT, Giannini C, Cloft HJ, Wood CP. Neuroimaging Findings in Cardiac Myxoma Patients: A Single-Center Case Series of 47 Patients. Cerebrovasc Dis. 2015; 40: (1-2)35-44. PMID: 26068450 DOI: 10.1159/000381833

Popescu BF, Guo Y, Jentoft ME, Parisi JE, Lennon VA, Pittock SJ, Weinshenker BG, Wingerchuk DM, Giannini C, Metz I, Bruck W, Shuster EA, Carter J, Boyd CD, Clardy SL, Cohen BA, Lucchinetti CF. Diagnostic utility of aquaporin-4 in the analysis of active demyelinating lesions. Neurology. 2015 Jan 13; 84: (2)148-58. PMID: 25503621 PMCID: 4336081 DOI: 10.1212/WNL.0000000000001126

Salvarani C, Brown RD Jr, Christianson T, Miller DV, Giannini C, Huston J 3rd, Hunder GG. An update of the Mayo Clinic cohort of patients with adult primary central nervous system vasculitis: description of 163 patients. Medicine (Baltimore). 2015 May; 94(21):e738. PMID: 26020379 PMCID: 4616419 DOI: 10.1097/MD.0000000000000738

Salvarani C, Brown RD Jr, Christianson TJ, Huston J 3rd, Giannini C, Miller DV, Hunder GG. Adult primary central nervous system vasculitis treatment and course: analysis of one hundred sixty-three patients. Arthritis Rheumatol. 2015 Jun; 67: (6)1637-45. PMID: 25708615 DOI: 10.1002/art.39068

Collins VP, Jones DTW, Giannini C. Pilocytic astrocytoma: pathology, molecular mechanisms and markers. Acta Neuropathol (Berl). 2015 Jun; 129(6):775-88.

Eckel-Passow JE, Lachance DH, Molinaro AM, Walsh KM, Decker PA, Sicotte H, Pekmezci M, Rice T, Kosel ML, Smirnov IV, Sarkar G, Caron AA, Kollmeyer TM, Praska CE, Chada AR, Halder C, Hansen HM, McCoy LS, Bracci PM, Marshall R, Zheng S, Reis GF, Pico AR, O'Neill BP, Buckner JC, Giannini C, Huse JT, Perry A, Tihan T, Berger MS, Chang SM, Prados MD, Wiemels J, Wiencke JK, Wrensch MR, Jenkins RB. Glioma Groups Based on 1p19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med. 2015 Jun 25; 372: (26)2499-508. PMID: 26061753 PMCID: 4489704 DOI: 10.1056/NEJMoa1407279


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Johnson DR, Fogh SE, Giannini C, Kaufmann TJ, Raghunathan A, Theodosopoulos PV, Clarke JL. Case- Based Review: Newly Diagnosed Glioblastoma Neuro-Oncology Practice.2015;2:(3)106-111.

Salvarani C, Brown RD Jr, Christianson TJ, Huston J 3rd, Giannini C, Miller DV, Muratore F, Hunder GG. Mycophenolate mofetil in primary central nervous system vasculitis. Semin Arthritis Rheum. 2015 Aug; 45: (1)55-9. PMID: 25800827 DOI: 10.1016/j.semarthrit.2015.02.008

Ma DJ, Galanis E, Anderson SK, Schiff D, Kaufmann TJ, Peller PJ, Giannini C, Brown PD, Uhm JH, McGraw S, Jaeckle KA, Flynn PJ, Ligon KL, Buckner JC, Sarkaria JN. A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K. Neuro Oncol. 2015 Sep; 17 (9):1261-9 Epub 2014 Dec 18 PMID: 25526733 PMCID: 4588750 DOI: 10.1093/neuonc/nou328

Vogelbaum MA, Hu C, Peereboom DM, Macdonald DR, Giannini C, Suh JH, Jenkins RB, Laack NN, Brachman DG, Shrieve DC, Souhami L, Mehta MP. Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131. J Neurooncol. 2015 Sep; 124 (3):413-20 Epub 2015 June 19 PMID: 26088460 PMCID: 4584176 DOI: 10.1007/s11060-015-1845-7

Ida CM, Rodriguez FJ, Burger PC, Caron AA, Jenkins SM, Spears GM, Aranguren DL, Lachance DH, Giannini C. Pleomorphic Xanthoastrocytoma: Natural History and Long-Term Follow-Up. Brain Pathol. 2015 Sep; 25: (5)575-86. PMID: 25318587 PMCID: 4400218 DOI: 10.1111/bpa.12217

Copeland WR, Van Gompel JJ, Giannini C, Eckel LJ, Koeller KK, Link MJ. Can Preoperative Imaging Predict Tumor Involvement of the Anterior Clinoid in Clinoid Region Meningiomas? Neurosurgery. 2015 Oct; 77: (4)525-9; discussion 530. PMID: 26120799 DOI: 10.1227/NEU.0000000000000873

Ariai MS, Eggers SD, Giannini C, Driscoll CL, Link MJ. Solitary Metastasis to the Facial/Vestibulocochlear Nerve Complex: Case Report and Review of the Literature. World Neurosurg. 2015 Oct; 84: (4)1178.e15-8. PMID: 26074432 DOI: 10.1016/j.wneu.2015.05.071

Leeper HE, Caron AA, Decker PA, Jenkins RB, Lachance DH, Giannini C. IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas. Oncotarget. 2015 Oct 6; 6 (30):30295-305 PMID: 26210286 PMCID: 4745799 DOI: 10.18632/oncotarget.4497

Brown PD, Anderson SK, Carrero XW, O'Neill BP, Giannini C, Galanis E, Shah SA, Abrams RA, Curran WJ Jr, Buckner JC, Shaw EG. Adult patients with supratentorial pilocytic astrocytoma: long-term follow-up of prospective multicenter clinical trial NCCTG-867251 (Alliance). Neurooncol Pract. 2015 Dec; 2 (4):199-204 Epub 2015 Aug 06 PMID: 26640699 PMCID: 4669035 DOI: 10.1093/nop/npv031

Graff-Radford J, Josephs KA, Parisi JE, Dickson DW, Giannini C, Boeve BF. Globular Glial Tauopathy Presenting as Semantic Variant Primary Progressive Aphasia. JAMA Neurol. 2016 Jan; 73: (1)123-5. PMID: 26571405 PMCID: 5300744 DOI: 10.1001/jamaneurol.2015.2711

Vaubel RA, Chen SG, Raleigh DR, Link MJ, Chicoine MR, Barani I, Jenkins SM, Aleff PA, Rodriguez FJ, Burger PC, Dahiya S, Perry A, Giannini C. Meningiomas With Rhabdoid Features Lacking Other Histologic Features of Malignancy: A Study of 44 Cases and Review of the Literature. J Neuropathol Exp Neurol. 2016 Jan; 75: (1)44-52. PMID: 26705409 PMCID: 5009417 DOI: 10.1093/jnen/nlv006

Amirian ES, Armstrong GN, Zhou R, Lau CC, Claus EB, Barnholtz-Sloan JS, Il'yasova D, Schildkraut J, Ali- Osman F, Sadetzki S, Johansen C, Houlston RS, Jenkins RB, Lachance D, Olson SH, Bernstein JL, Merrell RT, Wrensch MR, Davis FG, Lai R, Shete S, Amos CI, Scheurer ME, Aldape K, Alafuzoff I, Brannstrom T, Broholm H, Collins P, Giannini C, Rosenblum M, Tihan T, Melin BS, Bondy ML. The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium. Am J Epidemiol. 2016 Jan 15; 183: (2)85-91. PMID: 26656478 PMCID: 4706682 DOI: 10.1093/aje/kwv235

Yamada S, Kipp BR, Voss JS, Giannini C, Raghunathan A. Combined "Infiltrating Astrocytoma/Pleomorphic Xanthoastrocytoma" Harboring IDH1 R132H and BRAF V600E Mutations. Am J Surg Pathol. 2016 Feb; 40: (2)279-84. PMID: 26414224 DOI: 10.1097/PAS.0000000000000515

Flanagan EP, Kaufmann TJ, Krecke KN, Aksamit AJ, Pittock SJ, Keegan BM, Giannini C, Weinshenker BG. Discriminating long myelitis of neuromyelitis optica from sarcoidosis. Ann Neurol. 2016 Mar; 79: (3)437-47.

PMID: 26677112 DOI: 10.1002/ana.24582

Nauen D, Haley L, Lin MT, Perry A, Giannini C, Burger PC, Rodriguez FJ. Molecular Analysis of Pediatric Oligodendrogliomas Highlights Genetic Differences with Adult Counterparts and Other Pediatric Gliomas. Brain Pathol. 2016 Mar; 26: (2)206-14. PMID: 26206478 PMCID: 4724334 DOI: 10.1111/bpa.12291


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Bandopadhayay P, Ramkissoon LA, Jain P, Bergthold G, Wala J, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH, Han HJ, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P, Pages M, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S, Haas-Kogan DA, Phillips JJ, Santagata S, Stiles CD, Bradner JE, Jabado N, Goren A, Grill J, Ligon AH, Goumnerova L, Waanders AJ, Storm PB, Kieran MW, Ligon KL, Beroukhim R, Resnick AC. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nat Genet. 2016 Mar; 48: (3)273-82. PMID: 26829751 PMCID: 4767685 DOI: 10.1038/ng.3500

Fritchie KJ, Jin L, Rubin BP, Burger PC, Jenkins SM, Barthelmess S, Moskalev EA, Haller F, Oliveira AM, Giannini C. NAB2-STAT6 Gene Fusion in Meningeal Hemangiopericytoma and Solitary Fibrous Tumor. J Neuropathol Exp Neurol. 2016 Mar; 75: (3)263-71. PMID: 26883114 DOI: 10.1093/jnen/nlv026

Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AAN, Giannini C, Li KKW, Ng HK, Yao Y, Kumabe T, Tominaga T, Grajkowska WA, Perek-Polnik M, Low DCY, Seow WT, Chang KTE, Mora J, Pollack IF, Hamilton RL, Leary S, Moore AS, Ingram WJ, Hallahan AR, Jouvet A, Fevre-Montange M, Vasiljevic A, Faure-Conter C, Shofuda T, Kagawa N, Hashimoto N, Jabado N, Weil AG, Gayden T, Wataya T, Shalaby T, Grotzer M, Zitterbart K, Sterba J, Kren L, Hortobagyi T, Klekner A, Laszlo B, Pocza T, Hauser P, Schuller U, Jung S, Jang WY, French PJ, Kros JM, van Veelen MC, Massimi L, Leonard JR, Rubin JB, Vibhakar R, Chambless LB, Cooper MK, Thompson RC, Faria CC, Carvalho A, Nunes S, Pimentel J, Fan X, Muraszko KM, Lopez-Aguilar E, Lyden D, Garzia L, Shih DJH, Kijima N, Schneider C, Adamski J, Northcott PA, Kool M, Jones DTW, Chan JA, Nikolic A, Garre ML, Van Meir EG, Osuka S, Olson JJ, Jahangiri A, Castro BA, Gupta N, Weiss WA, Moxon-Emre I, Mabbott DJ, Lassaletta A, Hawkins CE, Tabori U, Drake J, Kulkarni A, Dirks P, Rutka JT, Korshunov A, Pfister SM, Packer RJ, Ramaswamy V, Taylor MD. Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis. Lancet Oncol. 2016 Apr; 17 (4):484-495 Epub 2016 Mar 12 PMID: 26976201 PMCID: 4907853 DOI: 10.1016/S1470-2045(15)00581-1

Salvarani C, Morris JM, Giannini C, Brown RD Jr, Christianson T, Hunder GG. Imaging Findings of Cerebral Amyloid Angiopathy, Abeta-Related Angiitis (ABRA), and Cerebral Amyloid Angiopathy-Related Inflammation: A Single-Institution 25-Year Experience. Medicine (Baltimore). 2016 May; 95: (20)e3613. PMID: 27196463 PMCID: 4902405 DOI: 10.1097/MD.0000000000003613

Hughes J, D Hughes J, Retzlaff A, Sims J, O'Brien E, Giannini C, Huston J 3rd, Van Gompel JJ. Adenoid Cystic Carcinoma Metastatic to the Pituitary: A Case Report and Discussion of Potential Diagnostic Value of Magnetic Resonance Elastography in Pituitary Tumors. World Neurosurg. 2016 Jul; 91:669.e11-4 Epub 2016 Mar 24 PMID: 27018011 DOI: 10.1016/j.wneu.2016.03.044

Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon RE, Lipp ES, Dunham C, Hukin J, Eisenstat DD, Fulton D, van Landeghem FK, Santi M, van Veelen ML, Van Meir EG, Osuka S, Fan X, Muraszko KM, Tirapelli DP, Oba-Shinjo SM, Marie SK, Carlotti CG, Lee JY, Rao AA, Giannini C, Faria CC, Nunes S, Mora J, Hamilton RL, Hauser P, Jabado N, Petrecca K, Jung S, Massimi L, Zollo M, Cinalli G, Bognar L, Klekner A, Hortobagyi T, Leary S, Ermoian RP, Olson JM, Leonard JR, Gardner C, Grajkowska WA, Chambless LB, Cain J, Eberhart CG, Ahsan S, Massimino M, Giangaspero F, Buttarelli FR, Packer RJ, Emery L, Yong WH, Soto H, Liau LM, Everson R, Grossbach A, Shalaby T, Grotzer M, Karajannis MA, Zagzag D, Wheeler H, von Hoff K, Alonso MM, Tunon T, Schuller U, Zitterbart K, Sterba J, Chan JA, Guzman M, Elbabaa SK, Colman H, Dhall G, Fisher PG, Fouladi M, Gajjar A, Goldman S, Hwang E, Kool M, Ladha H, Vera-Bolanos E, Wani K, Lieberman F, Mikkelsen T, Omuro AM, Pollack IF, Prados M, Robins HI, Soffietti R, Wu J, Metellus P, Tabori U, Bartels U, Bouffet E, Hawkins CE, Rutka JT, Dirks P, Pfister SM, Merchant TE, Gilbert MR, Armstrong TS, Korshunov A, Ellison DW, Taylor MD. Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis. J Clin Oncol. 2016 Jul 20; 34: (21)2468-77. PMID: 27269943 PMCID: 4962737 DOI: 10.1200/JCO.2015.65.7825

Carter JM, Howe BM, Hawse JR, Giannini C, Spinner RJ, Fritchie KJ. CTNNB1 Mutations and Estrogen Receptor Expression in Neuromuscular Choristoma and Its Associated Fibromatosis. Am J Surg Pathol. 2016 Oct; 40: (10)1368-74. PMID: 27259010 DOI: 10.1097/PAS.0000000000000673


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Konakondla S, Jayarao M, Skrade J, Giannini C, Workman MJ, Morgan CJ. Subependymal giant cell astrocytoma in a genetically negative tuberous sclerosis complex adult: Case report. Clin Neurol Neurosurg. 2016 Nov; 150:177-180. PMID: 27690251 DOI: 10.1016/j.clineuro.2016.09.015

Korfel A, Schlegel U, Johnson DR, Kaufmann T, Giannini C, Hirose T. Case-Based Review: Primary CNS Lymphoma Neuro-Oncology Practice.2016;In Press:

Graffeo CS, Leeper HE, Perry A, Uhm JH, Lachance DJ, Brown PD, Ma DJ, Van Gompel JJ, Giannini C, Johnson DR, Raghunathan A. Revisiting adjuvant radiotherapy after gross total resection of World Health Organization grade II meningioma World Neurosurgery. 2017; 103:655-63.

Graffeo CS, Perry A, Copeland WR III, Giannini C, Neff BA, Driscoll CLW, Link MJ. Synchronous tumors of the cerebellopontine angle World Neurosurgery. 2017; 98:632-43.

Prasad NK, Tubbs RS, Amrami KK, Dyck PJB, Mauermann ML, Giannini C, de Divitiis O, Spinner RJ. Can Intraneural Perineuriomas Occur Intradurally? An Anatomic Perspective. Neurosurgery. 2017 Feb 01; 80 (2):226-234 PMID: 28173435 DOI: 10.1093/neuros/nyw028

Peacock JG, Harmsen WS, Link MJ, Van Gompel JJ, Giannini C, Olsen KD, Garces YI, Neben Wittich MA, Ma DJ, Park SS, Foote RL. Risk of Delayed Lymph Node Metastasis in Clinically N0 Esthesioneuroblastoma. J Neurol Surg B Skull Base. 2017 Feb; 78 (1):68-74 Epub 2016 July 06 PMID: 28180046 PMCID: 5288109 DOI: 10.1055/s-0036-1584904

Graffeo CS, Perry A, Copeland WR 3rd, Giannini C, Neff BA, Driscoll CL, Link MJ. Synchronous Tumors of the Cerebellopontine Angle. World Neurosurg. 2017 Feb; 98:632-643 Epub 2016 Nov 12 PMID: 27836701 DOI: 10.1016/j.wneu.2016.11.002

Vaubel RA, Caron AA, Yamada S, Decker PA, Eckel Passow JE, Rodriguez FJ, Nageswara Rao AA, Lachance D, Parney I, Jenkins R, Giannini C. Recurrent copy number alterations in low-grade and anaplastic pleomorphic xanthoastrocytoma with and without BRAF V600E mutation. Brain Pathol. 2017 Feb 9 Epub 2017 Feb 09 PMID: 28181325 PMCID: 5807227 DOI: 10.1111/bpa.12495

Korfel A, Schlegel U, Johnson DR, Kaufmann TJ, Giannini C, Hirose T. Case-based review: Primary central nervous system lymphoma Neuro-Oncology Practice. 2017 Mar; 4 (1):46-59

Bale TA, Oviedo A, Kozakewich H, Giannini C, Davineni PK, Ligon K, Alexandrescu S. Intracranial myxoid mesenchymal tumors with EWSR1-CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? Brain Pathol. 2017 Mar 09; PMID: 28281318 DOI: 10.1111/bpa.12504

Johnson DR, Diehn FE, Giannini C, Jenkins RB, Jenkins SM, Parney IF, Kaufmann TJ. Genetically Defined Oligodendroglioma Is Characterized by Indistinct Tumor Borders at MRI. AJNR Am J Neuroradiol. 2017 Apr; 38 (4):678-684 Epub 2017 Jan 26 PMID: 28126746 DOI: 10.3174/ajnr.A5070

Shankar GM, Abedalthagafi M, Vaubel RA, Merrill PH, Nayyar N, Gill CM, Brewster R, Bi WL, Agarwalla PK, Thorner AR, Reardon DA, Al-Mefty O, Wen PY, Alexander BM, van Hummelen P, Batchelor TT, Ligon KL, Ligon AH, Meyerson M, Dunn IF, Beroukhim R, Louis DN, Perry A, Carter SL, Giannini C, Curry WT Jr, Cahill DP, Barker FG 2nd, Brastianos PK, Santagata S. Germline and somatic BAP1 mutations in high- grade rhabdoid meningiomas. Neuro Oncol. 2017 Apr 1; 19 (4):535-545 PMID: 28170043 PMCID: 5464371 DOI: 10.1093/neuonc/now235

Pekmezci M, Rice T, Molinaro AM, Walsh KM, Decker PA, Hansen H, Sicotte H, Kollmeyer TM, McCoy LS, Sarkar G, Perry A, Giannini C, Tihan T, Berger MS, Wiemels JL, Bracci PM, Eckel-Passow JE, Lachance DH, Clarke J, Taylor JW, Luks T, Wiencke JK, Jenkins RB, Wrensch MR. Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT. Acta Neuropathol. 2017 Jun; 133 (6):1001-1016 Epub 2017 Mar 02 PMID: 28255664 PMCID: 5432658 DOI: 10.1007/s00401-017-1690-1

Buckner J, Giannini C, Eckel-Passow J, Lachance D, Parney I, Laack N, Jenkins R. Management of diffuse low-grade gliomas in adults - use of molecular diagnostics. Nat Rev Neurol. 2017 Jun; 13: (6)340-351. PMID: 28497806 DOI: 10.1038/nrneurol.2017.54


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Cavalli FMG, Remke M, Rampasek L, Peacock J, Shih DJH, Luu B, Garzia L, Torchia J, Nor C, Morrissy AS, Agnihotri S, Thompson YY, Kuzan-Fischer CM, Farooq H, Isaev K, Daniels C, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska WA, Perek-Polnik M, Vasiljevic A, Faure-Conter C, Jouvet A, Giannini C, Nageswara Rao AA, Li KKW, Ng HK, Eberhart CG, Pollack IF, Hamilton RL, Gillespie GY, Olson JM, Leary S, Weiss WA, Lach B, Chambless LB, Thompson RC, Cooper MK, Vibhakar R, Hauser P, van Veelen MC, Kros JM, French PJ, Ra YS, Kumabe T, Lopez-Aguilar E, Zitterbart K, Sterba J, Finocchiaro G, Massimino M, Van Meir EG, Osuka S, Shofuda T, Klekner A, Zollo M, Leonard JR, Rubin JB, Jabado N, Albrecht S, Mora J, Van Meter TE, Jung S, Moore AS, Hallahan AR, Chan JA, Tirapelli DPC, Carlotti CG, Fouladi M, Pimentel J, Faria CC, Saad AG, Massimi L, Liau LM, Wheeler H, Nakamura H, Elbabaa SK, Perezpena- Diazconti M, Chico Ponce de Leon F, Robinson S, Zapotocky M, Lassaletta A, Huang A, Hawkins CE, Tabori U, Bouffet E, Bartels U, Dirks PB, Rutka JT, Bader GD, Reimand J, Goldenberg A, Ramaswamy V, Taylor MD. Intertumoral Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 2017 Jun 12; 31 (6):737-754.e6 PMID: 28609654 DOI: 10.1016/j.ccell.2017.05.005

Graffeo CS, Leeper HE, Perry A, Uhm JH, Lachance DJ, Brown PD, Ma DJ, Van Gompel JJ, Giannini C, Johnson DR, Raghunathan A. Revisiting Adjuvant Radiotherapy After Gross Total Resection of World Health Organization Grade II Meningioma. World Neurosurg. 2017 Jul; 103:655-663 Epub 2017 Apr 24 PMID: 28450233 DOI: 10.1016/j.wneu.2017.04.095

Brown PD, Ballman KV, Cerhan JH, Anderson SK, Carrero XW, Whitton AC, Greenspoon J, Parney IF, Laack NNI, Ashman JB, Bahary JP, Hadjipanayis CG, Urbanic JJ, Barker FG 2nd, Farace E, Khuntia D, Giannini C, Buckner JC, Galanis E, Roberge D. Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC.3): a multicentre, randomised, controlled, phase 3 trial. Lancet Oncol. 2017 Aug; 18 (8):1049-1060 Epub 2017 July 04 PMID: 28687377 PMCID: 5568757 DOI: 10.1016/S1470-2045(17)30441-2

Akkus Z, Ali I, Sedlar J, Agrawal JP, Parney IF, Giannini C, Erickson BJ. Predicting Deletion of Chromosomal Arms 1p/19q in Low-Grade Gliomas from MR Images Using Machine Intelligence. J Digit Imaging. 2017 Aug; 30 (4):469-476 PMID: 28600641 PMCID: 5537096 DOI: 10.1007/s10278-017-9984-3

Vaubel RA, Kollmeyer TM, Caron AA, Barr Fritcher EG, Voss JS, Liang H, Jenkins RB, Giannini C, Kipp BR. Synchronous gemistocytic astrocytoma IDH-mutant and oligodendroglioma IDH-mutant and 1p/19q- codeleted in a patient with CCDC26 polymorphism. Acta Neuropathol. 2017 Aug; 134 (2):317-319 Epub 2017 May 26 PMID: 28550371 DOI: 10.1007/s00401-017-1727-5

Galanis E, Anderson SK, Miller CR, Sarkaria JN, Jaeckle K, Buckner JC, Ligon KL, Ballman KV, Moore DF Jr, Nebozhyn M, Loboda A, Schiff D, Ahluwalia MS, Lee EQ, Gerstner ER, Lesser GJ, Prados M, Grossman SA, Cerhan J, Giannini C, Wen PY, Alliance for Clinical Trials in Oncology and ABTC. Phase I/II Trial of Vorinostat Combined with Temozolomide and Radiation Therapy for Newly Diagnosed Glioblastoma: Final Results of Alliance N0874/ABTC 02. Neuro Oncol. 2017 Aug 22 [Epub ahead of print] PMID: 29016887 DOI: 10.1093/neuonc/nox161

Lassaletta A, Zapotocky M, Mistry M, Ramaswamy V, Honnorat M, Krishnatry R, Guerreiro Stucklin A, Zhukova N, Arnoldo A, Ryall S, Ling C, McKeown T, Loukides J, Cruz O, de Torres C, Ho CY, Packer RJ, Tatevossian R, Qaddoumi I, Harreld JH, Dalton JD, Mulcahy-Levy J, Foreman N, Karajannis MA, Wang S, Snuderl M, Nageswara Rao A, Giannini C, Kieran M, Ligon KL, Garre ML, Nozza P, Mascelli S, Raso A, Mueller S, Nicolaides T, Silva K, Perbet R, Vasiljevic A, Faure Conter C, Frappaz D, Leary S, Crane C, Chan A, Ng HK, Shi ZF, Mao Y, Finch E, Eisenstat D, Wilson B, Carret AS, Hauser P, Sumerauer D, Krskova L, Larouche V, Fleming A, Zelcer S, Jabado N, Rutka JT, Dirks P, Taylor MD, Chen S, Bartels U, Huang A, Ellison DW, Bouffet E, Hawkins C, Tabori U. Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas. J Clin Oncol. 2017 Sep 1; 35 (25):2934-2941 Epub 2017 July 20 PMID: 28727518 PMCID: 5791837 DOI: 10.1200/JCO.2016.71.8726

Ida CM, Butz ML, Jenkins RB, Sarkaria JN, Kitange GJ, Giannini C, Kipp BR. Real-Time Methylation- Specific Polymerase Chain Reaction for MGMT Promoter Methylation Clinical Testing in Glioblastoma: An Alternative Detection Method for a Heterogeneous Process. Am J Clin Pathol. 2017 Oct 01; 148 (4):296-307 PMID: 28967952 DOI: 10.1093/ajcp/aqx073

Johnson DR, Guerin JB, Giannini C, Morris JM, Eckel LJ, Kaufmann TJ. 2016 Updates to the WHO Brain Tumor Classification System: What the Radiologist Needs to Know. Radiographics. 2017 Nov-Dec; 37 (7):2164-2180 Epub 2017 Oct 13 PMID: 29028423 DOI: 10.1148/rg.2017170037


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Takami H, Graffeo CS, Perry A, Raghunathan A, Jenkins RB, Giannini C, Burns TC. Giant Cell Ependymoma of Lateral Ventricle: Case Report, Literature Review, and Analysis of Prognostic Factors and Genetic Profile. World Neurosurg. 2017 Dec; 108:997.e9-997.e14 Epub 2017 Sept 21 PMID: 28943417 DOI: 10.1016/j.wneu.2017.09.088

Kiyofuji S, Perry A, Graffeo CS, Giannini C, Link MJ. The dangers of the "Head Down" position in patients with untreated pituitary macroadenomas: case series and review of literature. Pituitary. 2017 Dec 13 [Epub ahead of print] PMID: 29236218 DOI: 10.1007/s11102-017-0851-5

Nagy G, McCutcheon BA, Giannini C, Link MJ, Pollock BE. Radiation-Induced Cavernous Malformations After Single-Fraction Meningioma Radiosurgery. Oper Neurosurg (Hagerstown). 2017 Dec 21 [Epub ahead of print] PMID: 29281070 DOI: 10.1093/ons/opx254

Swanson AA, Giannini C, Folpe AL, Van Dyke DL, Amrami KK, Michalak WA, Vaubel RA. Low-grade fibromyxoid sarcoma arising within the median nerve. Neuropathology. 2018 Jan 3 Epub 2018 Jan 03 PMID: 29314300 DOI: 10.1111/neup.12453

Schiff D, Jaeckle KA, Anderson SK, Galanis E, Giannini C, Buckner JC, Stella P, Flynn PJ, Erickson BJ, Schwerkoske JF, Kaluza V, Twohy E, Dancey J, Wright J, Sarkaria JN. Phase 1/2 trial of temsirolimus and sorafenib in the treatment of patients with recurrent glioblastoma: North Central Cancer Treatment Group Study/Alliance N0572. Cancer. 2018 Jan 3 Epub 2018 Jan 03 PMID: 29313954 DOI: 10.1002/cncr.31219

Johann PD, Bens S, Oyen F, Wagener R, Giannini C, Perry A, Raisanen JM, Reis GF, Nobusawa S, Arita K, Felsberg J, Reifenberger G, Agaimy A, Buslei R, Capper D, Pfister SM, Schneppenheim R, Siebert R, Fruhwald MC, Paulus W, Kool M, Hasselblatt M. Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup. Am J Surg Pathol. 2018 Jan 10 [Epub ahead of print] PMID: 29324471 DOI: 10.1097/PAS.0000000000001023

Youland RS, Pafundi DH, Brinkmann DH, Lowe VJ, Morris JM, Kemp BJ, Hunt CH, Giannini C, Parney IF, Laack NN. Prospective trial evaluating the sensitivity and specificity of 3,4-dihydroxy-6-[18F]-fluoro-L- phenylalanine (18F-DOPA) PET and MRI in patients with recurrent gliomas. J Neurooncol. 2018 Jan 13 [Epub ahead of print] PMID: 29330751 DOI: 10.1007/s11060-018-2750-7

Sarkaria JN, Hu LS, Parney IF, Pafundi DH, Brinkmann DH, Laack NN, Giannini C, Burns TC, Kizilbash SH, Laramy JK, Swanson KR, Kaufmann TJ, Brown PD, Agar NYR, Galanis E, Buckner JC, Elmquist WF. Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data. Neuro Oncol. 2018 Jan 22; 20 (2):184-191 PMID: 29016900 PMCID: 5777482 DOI: 10.1093/neuonc/nox175

Sahm F, Reuss DE, Giannini C. WHO 2016 classification: changes and advancements in the diagnosis of miscellaneous primary CNS tumours. Neuropathol Appl Neurobiol. 2018 Feb; 44 (2):163-171 PMID: 28295484 DOI: 10.1111/nan.12397

Salvarani C, Brown RD Jr, Christianson TJH, Huston J 3rd, Ansell SM, Giannini C, Hunder GG. Primary central nervous system vasculitis associated with lymphoma. Neurology. 2018 Feb 2 Epub 2018 Feb 02 PMID: 29429967 DOI: 10.1212/WNL.0000000000005062

Non-Peer-reviewed Articles

1. Giannini C. Nerve fiber regeneration after focal nerve injury: pathologic events and mechanisms. Proc. XIth International Congress of Neuropathology, Kyoto Sept 2-8 1990, Neuropath. Suppl. 4, 706-709, 1991.

2. Giannini C, Garre ML, Oka H, Scheithauer BW. Atypical teratoid/rhabdoid tumor of the central nervous system: an aggressive pediatric brain tumor. Pathology Case Review. 1998;3(6):301-8.

3. Giannini C, Scheithauer BW. Classification and grading of diffuse gliomas. Pathology Case Review. 1998;3:274-80.

4. Uhm JH, Johnson D, Porter Umphrey AB, Giannini C, Parney IF, Rhodes DJ, Zahasky KM, Vora SA, Buckner JC, Lachance DH. Low-Grade Glioma (Adult) AskMayoExpert Clinical Answers.02/12/2016;


Book Chapters

1. Dyck PJ, Giannini C, Lais A. Pathologic alterations of nerves. In: Dyck PJ, Thomas PK, Griffin JW, Low PA, Poduslo JF, editors. Peripheral Neuropathy. 3rd Edition. Volume 1. Philadelphia: W. B. Saunders Co.; 1993. p. 514-95.

2. Giannini C, Scheithauer BW. Classification and grading of gliomas. Neuro-Oncology part II. In: Handbook of Clinical Neurology. CJ Vecht, Ed. Vinken & Bruyen, 1997, Vol 68, pp 1-31.

3. Giannini C, Dyck PJ. Pathologic alterations in human diabetic polyneuropathy. In: Dyck PJ, Thomas PK, editors. Diabetic Neuropathy. 2nd Edition. Philadelphia: W. B. Saunders Company; 1999. p. 270-95.

4. Giannini C, Dyck PJ. Pathophysiology of nerve compression. In: Dyck PJ, Thomas PK, editors. Diabetic Neuropathy. 2nd Edition. Philadelphia: W. B. Saunders Company; 1999. p. 509-15.

5. Scheithauer BW, Giannini C, Woodruff JM. Perineurioma. In: WHO Classification of Tumors - Pathology & Genetics Tumors of the Nervous System. Kleihues P, Cavanee WK, Ed. IARC Press 2000:45-51.

6. Burger PC, Scheithauer BW, Paulus W, Szymas J, Giannini C. Pilocytic astrocytoma. In: WHO Classification of Tumors - Pathology & Genetics Tumors of the Nervous System. Kleihues P, Cavanee WK, Ed. IARC Press 2000:45-51.

7. Kepes JJ, Louis DN, Giannini C, Paulus W. Pleomorphic xanthoastrocytoma. In: WHO Classification of Tumors - Pathology & Genetics Tumors of the Nervous System. Kleihues P, Cavanee WK, Ed. IARC Press 2000:52-54.

8. Ludwig J, Adams VI, Edwards WD, Giannini C, Waters BL. Alphabetic listing of diseases and conditions. In: Ludwig J, editor. Handbook of autopsy practice. 3rd Edition. Totowa: Humana Press; 2002. p. 169-547.

9. Giannini C, Okazaki H. Nervous system. In: Ludwig J, editor. Handbook of autopsy practice. 3rd Edition. Totowa: Humana Press; 2002. p. 65-84.

10. Dyck PJ, Dyck PJB, Giannini C, Sahenk Z, Windebank AJ, Engelstad J. Peripheral nerves. In: Graham DI, Lantos PL, editors. Greenfield's neuropathology. 7th Edition. Volume 2. London: Arnold; 2002. p. 551-675.

11. Giannini C, Okasaki H. The nervous system, Part I, Chapter 6. In: Handbook of Autopsy Practice, 3rd Ed. Ludwig J, Ed. Humana Press Totowa, NJ 2002; 65-84.

12. Giannini C, Scheithauer BW. Tumors of the peripheral nervous system (including the craniospinal nerve roots). In: Nelson JS, et al, editors. Principles and practice of neuropathology. 2nd Edition. Oxford: Oxford University Press; 2003. p. 425-47.

13. Giannini C. Tumors and tumor-like conditions of peripheral nerve. In: Dyck PJ, Thomas PK, editors. Peripheral Neuropathy. 4th Edition. Volume 2. Philadelphia: Elsevier Saunders; 2005. p. 2585-606.

14. Rao RD, Brown PD, Giannini C, Maher CO, Meyer FB, Galanis E, Erickson BJ, Buckner JC. Central nervous system tumors. In: Chang AE, et al, editors. Oncology: an evidence-based approach. New York: Springer; 2006. p. 487-505.

15. Giannini C, Rushing EJ, Hainfeliner JA. Haemangiopericytoma. In: Louis DN, et al, editors. WHO classification of tumours of the central nervous system. 4th Edition. Lyon: International Agency for Research on Cancer; 2007. (World Health Organization Classification of Tumours.). p. 178-80.

16. Giannini C, Paulus W, Louis DN, Liberski P. Pleomorphic xanthoastrocytoma. In: Louis DN, et al, editors. WHO classification of tumours of the central nervous system. 4th Edition. Lyon: International Agency for Research on Cancer; 2007. (World Health Organization Classification of Tumours.). p. 22-4.

17. Giannini C, Okazaki H. Nervous system. In: Waters BL editor. Handbook of autopsy practice. 4th Edition. Totowa: Springer; 2009. p. 51-68.

18. Fogelson JL, Link MJ, Olsen KD, Moore EJ, Giannini C, Foote RL, Buckner JC. Esthesioneuroblastoma: management and outcome. In: Kaye AH , Laws ER. Brain tumors. 3 ed. New York: Elsevier Saunders; 2012. p. 767-78.

19. Zuccoli G, Pipitone N, Giannini C, Salvarani C. Central nervous system vasculitis. In: Massimo Filippi. Oxford Textbook of Neuroimaging Oxford University Press; Oct 2015.

20. Salvarani C, Brown RD Jr, Giannini C, Hunder GG. Adult primary central nervous system vasculitis. In: Systemic vasculitides: current status and perspectives. Springer; 2016. p. 245-57.


Editorials

1. Scheithauer BW, Giannini C. Surgical Pathology. Path Case Review. 1998;3(6):271-3.

2. Scheithauer BW, Giannini C, Guest Editors. Surgical Neuropathology in: Pathology Case Reviews, Ed-in- Chief Steven G. Silverberg Neuropathol. 1998 Nov; 3, #6.

Commentaries

1. Giannini C, Meyer FB. Biopsies and neuropathology. J Neurosurg. 2010 Aug; 113(2):167-8; discussion 168- 9. PMID:20136395 DOI:10.3171/2009.12.JNS091534

2. Mahan MA, Giannini C, Spinner RJ. Letter to the editor: fibrolipoma. J Neurosurg Spine. 2013 Sep; 19 (3):392-3. Epub 2013 Jul 26 PMID:23889185 DOI:10.3171/2012.11.SPINE12909

Abstracts

1. Rossi B, Giannini C, Siciliano G, Sartucci F. The role of the tactile pressure imput in the habituation phenomenon of the trigemino-facial reflex. Electroenceph. Clin. Neurophysiol. 61,3,S209, 1985. (XIth International Congress of EEG and Clinical Neurophysiology, London U.K, August 25-30, 1985).

2. Cavallaro T, Giannini C, Mezzina C, Radin E, Monaco S, Rizzuto N. The Crow-Fukase syndrome. Ital. J. Neurol. Sci. 8:177,1987 (XXII Congresso della Associazione Italiana di Neuropatologia, Padova, Italy, June 4-6, 1987).

3. Giannini C, Lais A, Dyck PJ. Numbers and sizes oh MF and UMF regenerating after single crush, multiple crush and autologous graft. Clin Neuropathol 7; 166, 1988 (3rd European meeting of Neuropathology, Verona, September 27-29, 1988) .

4. Yoshikawa H, Giannini C, Poduslo JF, Dyck PJ. Polyglucosan body axonal enlargement increases myelin spiral length but not lamellar number. (Abstract 831p). Neurology. 1990 Apr; 40(4 Suppl 1):344.

5. Giannini C, Dyck PJ. Schwann cell basement membrane fate in permanent nerve transection. Ital. J. Neurol. Sci. 11:201,1990; (XXVI Congresso della Associazione Italiana di Neuropatologia, Sestri Levante, Genova, May 24-26, 1990).

6. Giannini C, Englestad J, Dyck PJ. Basement membrane reduplication and pericyte degeneration of endoneurial microvessels compared in diabetic and other neuropathies. (Abstract no. P37-8). Brain Pathol. 1991; 4:560.

7. Ferrari S, Bonetti B, Monaco S, Giannini C, Nardelli E, Tedesco F, Rizzuto N. Endoneural injection of anti- MAG, IgM: morphological and immunohistochemical study. Clinic.Neuropathol. 10;152,1991; (XXVII Congresso della Associazione Italiana di Neuropatologia, Taormina, 23-25 May, 1991).

8. Bonetti B, Monaco S, Giannini C, Nardelli E, Ferrari S, Moretto G, Rizzuto N. Resident macrophages of human PNS constitutively express HLA-DR, CR3 and CD4. Ital. J. Neurol. Sci. Supp.12;15, 1991 (XXVII Congresso nazionale della Societa' Italiana di Neurologia, Sorrento October 21-26, 1991).

9. Ferrari S, Nardelli E, Moretto G, Monaco S, Bonetti B, Giannini C, Steck AJ, Rizzuto N. Anti-GM1 ganglioside antibodies recognize different nervous tissue elements. Ital. J. Neurol. Sci. Suppl.12;16, 1991 (XXVII Congresso nazionale della Societa' Italiana di Neurologia, Sorrento 21-26 1991 Oct).

10. Giannini C, Monaco S, Nardelli E, Tedesco F, Kirschfink M, Bonetti B, Ferrari S, Moretto G, Zanette G, Rizzuto N. Inherited neuroaxonal dystrophy in C6 deficient rabbits. Ital. J. Neurol. Sci. Suppl.12;97, 1991 (XXVII Congresso nazionale della Societa' Italiana di Neurologia, Sorrento 21-26 1991 Oct).

11. Nardelli E, Monaco S, Ferrari S, Bonetti B, Giannini C, Anzini P, Zanette G, Bhakdi S, Tedesco F, Steck AJ. Experimental autoimmune neuropathy and antigangliosides antibodies. J.Neuroimmunol. Suppl.1; 53, 1991 (3rd Congress of International Society of Neuroimmunology, Jerusalem October 27- 1991 Nov 1).

12. Giannini C, Dyck PJ. Basement membrane reduplication and pericyte degeneration of endoneurial microvessels compared in diabetic and other neuropathies. Brain Pathol 4; 560, 1994 (XIIth International congress of Neuropathology Toronto, Canada September 17-23, 1994).

13. Aksamit AJ, Giannini C, Lloyd R, Fletcher G, Parisi J. Progressive multifocal leukoencephalopathy: clearing of virus associated with extensive inflammation and MRI gadolinium enhancement. Ann Neurol 38:346, 1995.


14. Giannini C, Wenger D, Unni KK, Scheithauer BW. Pigmented villonodular synovitis of the spine. J Neuropath Exp Neurol 54; issue 5, 1995; (71st Annual meeting of the American Association of Neuropathology, San Antonio, June 7-11, 1995).

15. Suarez GA, Giannini C, Bosch EP, Barohn RJ, Wodak J, Ebeling P, Anderson R, McKeever PE, Bromberg MB, Dyck PJ. Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis. Peripheral Nerve Society Meeting, Antalya, Turkey, October 6-9, 1995.

16. Perry A, Giannini C, Scheithauer BW, Seo IS, Johnson PC. Combined pleomorphic xanthoastrocytomas and ganglioglioma: report of three cases. (Abstract 827). Lab Invest. 1996 Jan; 74:142A.

17. Perry A, Giannini C, Scheithauer BW, Seo IS, Johnson PC. Combined pleomorphic xanthoastrocytomas and ganglioglioma: report of three cases. (Abstract 827). Mod Pathol. 1996 Jan; 9:142A.

18. Calle-Rodriguez R, Scheithauer BW, Lloyd RV, Giannini C, Kovacs K, Ebright A, Davis DH, Abboud C. Prolactinomas: a clinicopathologic and proliferative marker study. (Abstract 258). Lab Invest. 1996 Jan; 74:47A.

19. Calle-Rodriguez R, Scheithauer BW, Lloyd RV, Giannini C, Kovacs K, Ebright A, Davis DH, Abboud C. Prolactinomas: a clinicopathologic and proliferative marker study. (Abstract 258). Mod Pathol. 1996 Jan; 9:47A.

20. Calle-Rodrigue R, Scheithauer BW, Lloyd RV, Giannini C, Kovacs K. Prolactinomas: a clinicopathologic and proliferation marker study. Lab Investig 75, 47A, 1996; (Annual meeting United States and Canadian Academy of Pathology, Washington DC, USA, March 23-29, 1996).

21. Giannini C, Parisi JE. Unknown Case Presentation. Annual Meeting of the American Association of Neuropathologists, Vancouver BC, Canada, 1996 Jun.

22. Giannini C, Scheithauer BW, Burger PC, Christensen MR, Wollan PC, Sebo TJ, Forsyth PA, Hayostek CJ. The MIB-1 LI in pilocytic and diffuse astrocytomas. J Neuropath Exp Neurol 55; issue 5, 1996; (72nd Annual Meeting of the American Association of Neuropathology, Vancouver, Canada, June 11-16, 1996).

23. Giannini C, Wollan P, Scheithauer BW, Sebo TJ, Hill E, Plummer T. The MIB-1 labeling index: a critical assessment of staining and quantification methods. Lab Invest. 1997; 76(1):150A.

24. Kovacs K, Giannini C, Scheithauer BW, Stefaneanu L, Lloyd R, Horvath E. The pituitary gland in ataxia- telangiectasia syndrome. A histologic, immunocytochemical and in situ hybridization study of three cases. Lab Invest. 1997; 76(1):150A.

25. Brat DJ, Giannini C, Scheithauer BW, Burger PC. Primary CNS melanocytic neoplasms. Lab Invest 76, 149A; (Annual Meeting United States and Canadian Academy of Pathology, Orlando, FL, USA, March 1-7, 1997).

26. Evidente VH, Adler C, Conley C, Giannini C, Parisi J, Fletcher J. Progressive cerebellar syndrome due to Erdheim-Chester disease. (Abstract p06.106). Neurology. 1997 Mar; 48(3 Suppl):A433.

27. Giannini C, Scheithauer BW, Burger PC, Lach B, O'Neill BP. Prognostic factors in pleomorphic xanthoastrocytoma. J Neuropath Exp Neurol 56; 606, 1997; (73rd Annual Meeting of the American Association of Neuropathology, Pittsburgh, June 10-15, 1997).

28. Giannini C, Scheithauer BW, Davis DH, Fox MW, Rasmussen AG, Hellbusch LC, Mccormick SR. Hemangioblastoma of peripheral nerve. Lab Invest. 1998; 78(1):159A.

29. Hirose T, Giannini C, Scheithauer BW, Lopes B, Vandenberg SR. Pleomorphic xanthoastrocytoma: an ultrastructural study. Arch Anat Cytol Path Clin Exp Path, 46; 540, 1998; (XXII International Congress of the International Academy of Pathology, Nice, France, October 18 -23, 1998).

30. Vege KS, Giannini C, Scheithauer BW. The immunophenotype of ependymoma. Lab Invest. 1998; 78 (1):162A.

31. Giannini C, Scheithauer BW, Davis DH, Fox MW, Rasmussen AG, Hellbusch LC, McCormick SR. Hemangioblastoma of peripheral nerve. Lab Invest 77, 159A, 1998; (Annual meeting, United States and Canadian Academy of Pathology, Boston, Massachusetts, USA, February 28- 1998 Mar 6).

32. Vege KS, Giannini C, Scheithauer BW. The immunophenotype of ependymoma. Lab Investig 77, 162A, 1998; (Annual meeting, United States and Canadian Academy of Pathology, Boston, Massachusetts, USA, February 28- 1998 Mar 6).


33. Giannini C, Lopes B, Scheithauer BW, Hirose T, Vandenberg SR, Kros M. Immunophenotype of pleomorphic xantoastrocytoma. J Neuropath Exp Neurol 57; 501, 1998; (74th Annual meeting of the American Association of Neuropathology, Minneapolis, MN, USA, June 18-21, 1998).

34. Cenacchi G, Roncaroli F, Giannini C, Cerasoli S, Giangaspero F. Non embryonal malignant tumors of CNS with neuronal differentiation. J Neuropath Exp Neurol 57; 519, 1998; (74th Annual meeting of the American Association of Neuropathology, Minneapolis, MN, USA, June 18-21, 1998).

35. Giannini C, Scheithauer BW, Mork SJ, Keeney GL, Nascimento AG, Tazelaar HD, Crotty T, Riepe R, Pernicone P, Altermatt H, Kros JM, Graeber M, Bausermann S, Burger PC, Weaver A. Oligodendrogliomas: reproducibility of grading parameters. J Neuropath Exp Neurol 58; 519, 1999; (75th Annual meeting of the American Association of Neuropathology, Portland, OR, USA, June 17-20, 1999).

36. Giannini C, Weaver A, Scheithauer BW, Burger P, Kros M, Mork S, Graeber M, Bauserman S, Burton J, Buckner J. Prognostic factors in oligodendroglioma. Lab Invest. 2000 Jan; 80(1):194A.

37. Giannini C, Scheithauer BW, Mork SJ, Keeney GL, Nascimento AG, Tazelaar HD, Crotty T, Riepe R, Pernicone P, Altermatt H, Kros JM, Graeber M, Bausermann S, Burger PC. Prognostic factors in oligodendroglioma. Annual meeting, United States and Canadian Academy of Pathology, New Orleans, Lousiana, USA, March 25-31, 2000.

38. Giannini C, Scheithauer BW, Mork SJ, Keeney GL, Nascimento AG, Tazelaar HD, Crotty T, Riepe R, Pernicone P, Altermatt H, Kros JM, Graeber M, Bausermann S, Burger PC. Prognostic factors in oligodendroglioma. J Neuropath Exp Neurol 50, 2000. 76th Annual meeting of the American Association of Neuropathology. Atlanta, GA, 2000 Jun 8-11.

39. Sciot R, Giannini C, Dei Tos AP. Primary peripheral PNET/Ewing's sarcoma of the dura: a clinicopathologic entity distinct from central PNET. Brain Pathol; (XIV International Congress of Neuropathology, Birmingham, England, UK, September 3-6, 2000).

40. Giannini C, Hebrink D, Scheithauer BW, Tos APD, James CD. Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma (PXA). Lab Invest. 2001 Jan; 81(1):207A.

41. Giannini C, Hebrink D, Dei Tos AP, Scheithauer BW, James CD. Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma. Annual meeting, United States and Canadian Academy of Pathology. Atlanta, GA, USA, March 3-9, 2001.

42. Buckner J, Jaeckle K, Galanis E, Uhm J, O'Neill B, Moynihan T, Brown P, Sarkaria J, Schomberg P, Erickson B, Schaefer P, Flynn P, Reid J, Jenkins R, James C, Scheithauer BW, Giannini C, O'Fallon JR. North Central Cancer Treatment Group (NCCTG) Neuro-Oncology Program. (Abstract). 14th International Conference on Brain Tumor Research and Therapy. Asheville, NC. 2001 May.

43. Buckner J, Jaeckle K, Galanis E, Uhm J, O'Neill B, Moynihan T, Brown P, Sarkaria J, Schomberg P, Erickson B, Schaefer P, Flynn P, Reid J, Jenkins R, James C, Scheithauer BW, Giannini C, O'Fallon JR. North Central Cancer Treatment Group (NCCTG) neuro-oncology program. Neuro-oncol. 2001 Oct; 3(Suppl

1) :S6-7. Abstract no. 22.

44. Buckner JC, Scheithauer BW, Dinapoli RP, Votava HJ, Giannini C, Iturria N, O'Fallon J. Comparison of mixed anaplastic oligoastrocytoma and high-grade astrocytoma in North Central Cancer Treatment Group (NCCTG) clinical trials of high-grade glioma (Abstract 305). Program/Proc Am Soc Clin Oncol. 2002; 21 (1):77a.

45. O'Neill BP, Aksamit AJ, Giannini C. Primary CNS lymphoma (PCNSL), progressive multifocal leukoencephalopathy (PML), and JC virus (JCV); coincidental intersection or interaction? (Abstract 433). Ann Oncol. 2002; 13(Suppl 2):124.

46. Rao RD, Scheithauer BW, Giannini C, Iturria NL, O'Fallon JR, Schaefer PL, Buckner JC. Prognostic significance of histologic subtyping in high grade astrocytoma: North Central Cancer Treatment Group (NCCTG) results (Abstract 283). Program/Proc Am Soc Clin Oncol. 2002; 21(1):71a.

47. Pollock BE, Stafford SL, Utter A, Gorman DA, Giannini C, Schreiner SA. Radiosurgery is equivalent to complete tumor resection (Simpson Grade 1) for patients with small- to moderate-sized meningiomas. American Association of Neurological Surgeons; 2002, Chicago, IL.

48. O'Neill BP, Caselli RJ, Aksamit AJ, Giannini C. Simultaneous cerebral lymphoma infiltration and progressive multifocal leukoencephalopathy (PML). Ann Neurol, 2002; 52:S79.


49. Phuong LK, Peng KW, Allen C, Giannini C, TenEyck CJ, Russell SJ, Galanis E. Use of a vaccine strain of measles virus genetically engineered to produce CEA as a novel therapeutic agent against glioblastoma multiforme. (Abstract). Molecular Therapy. 2002; 5(5):S302.

50. Pandita A, Hebrink D, Mohammadzadeh G, Micaleff J, Frederick L, Giannini C, Guha A, James CD. Analysis of EGFR amplification in paired cell lines and xenografts established from human glioblastomas. Proc Annu Meet Am Assoc Cancer Res. 2002 Mar; 43:298.

51. O'Neill BP, Kurtin PJ, Aksamit AJ, Giannini C. Simultaneous cerebral chronic lymphocytic leukemia (CLL) infiltration and progressive multifocal leukoencephalopathy (PML): coincidence or interaction? (Abstract 298). Neuro-oncol. 2002 Sep; 4(Suppl 1):S70.

52. Phuong LK, Allen C, Peng KW, Giannini C, TenEyck CJ, Russell S, Galanis E. Use of a vaccine strain of measles virus genetically engineered to produce CEA as a novel therapeutic agent against glioblastoma multiforme (Abstract 324). Neuro-oncol. 2002 Sep; 4(Suppl 1):S76.

53. Pandita A, Zadeh G, Hebrink D, Schroeder M, Micaleff J, Frederick L, Qian BP, Giannini C, Guba A, James CD. Investigating EGFR amplification in xenografts and their derived cell lines established from human glioblastomas (Abstract 140). Neuro-oncol. 2002 Oct; 4(4):345.

54. Sarkaria JN, Carlson BL, Schroeder M, Giannini C, Ballman K, James D (2003) Evaluation of the radiosensitizing effects of OSI-774 or RAD001 in serially transplantable orthotopic GBM xenograft lines. 2003 AACR-NCI-EORTC International Conference Molecular Targets and Cancer Therapeutics. Clinical Cancer Research 9: page 6211s, abstract C31.

55. Khoo TK, Fealey R, Giannini C, Atkinson J. Chordoid glioma of the third ventricle: a case of a rare tumor with resultant pituitary dysfunction. Society of Hospital Medicine (SHM) midwest chapter, Chicago, Sept 12- 13,. 2003;

56. Rao RD, Jenkins RB, Scheithauer BW, O'Fallon JR, Furth AF, Iturria N, Giannini C, Schaefer P, Buckner JC. Correlations between phenotype and cytogenetic aberrations in high grade astrocytomas Proc Am Soc Clin Oncol. 2003; 22:106. Abstract no. 422.

57. McWilliams RR, Giannini C, Hay ID, Atkinson JL, Stafford SL, Buckner JC. Management of brain metastases from thyroid cancer: a study of 16 pathologically confirmed cases over twenty-five years. (Abstract 448). Proc Am Soc Clin Oncol. 22:112, 2003.

58. Buckner JC, Scheithauer BW, O'Fallon JR, Schaefer P, Giannini C, Ballman K, Jenkins R. P53, EGFR, and PTEN as markers of diagnosis and prognosis in patients with anaplastic glioma enrolled in NCCTG clinical trials. Proc Am Soc Clin Oncol. 2003; 22:98.

59. McDonald JM, Tremont-Lukats I, Hess K, Groves M, Colman H, Burger P, Louis DN, Giannini C, Fuller G, Passe S, Jenkins R, Zhang W, Aldape K. Histologic features and 1p/19q loss are independent predictors of survival in anaplastic oligodendroglioma (AO) (Abstract PA-11). Neuro-oncol. 2003 Oct; 5(4):327.

60. Carlson BL, Schroeder MA, Mladek AC, Giannini C, James CD, Sarkaria JN. Radiosensitization by OSI-774 of serially transplantable human GBM xenografts (Abstract MO-01). Neuro-oncol. 2003 Oct; 5(4):321.

61. Leenstra JL, Brown PD, Frechette CM, Giannini C, Stafford SL, Pollock BE, Schild SE, Schild SE.. Central neurocytomas, the Mayo Clinic experience (Abstract 2123) International Journal of Radiation Oncology, Biology, Physics. 2004; 60: (1 Suppl)S407-8.

62. Tu P, Giannini C, Burack R, O'Neill BP, Yachnis AT, Perry A. Marginal zone lymphoma (maltoma) of the CNS: a clinico-pathologic and genetic series of 7 cases (Abstract 34). Journal of Neuropathology & Experimental Neurology. 2004 May; 63(5):518.

63. Rodriguez FJ, Crum B, Scheithauer BW, Mokri B, Giannini C. Vascular malformations-type intramedullary changes in spinal cord biopsied for suspicion of neoplasia (Abstract 152). Journal of Neuropathology & Experimental Neurology. 2004 May; 63(5):548.

64. Buckner JC, Aldape KD, Ballman K, Scheithauer BW, Burger PC, Giannini C, Schaefer PL, Jenkins RB, James CD. Immunohistochemical detection of EGFRvIII and prognostic significance in patients with malignant glioma enrolled in NCCTG clinical trials (Abstract 1508). Program/Proceedings of the American Society of Clinical Oncology. 2004 Jul 15; 22(14S):109s.


65. Jaeckle K, Ballman K, Uhm J, O'Fallon J, Schomberg P, Scheithauer B, Giannini C, Flynn P, Buckner J. Relationship of adminstration of enzyme-inducing anticonvulsants (EIAC) to survival in patients with glioblastoma: a North Central Cancer Treatment Group (NCCTG) study (Abstract TA-27). Neuro-oncol. 2004 Oct; 6(4):376.

66. Jaeckle K, Ballman K, O'Fallon J, Scheithauer B, Giannini C, Moynihan T, Buckner J. Response to pre- radiation chemotherapy as a predictor of survival in patients with newly diagnosed malignant astrocytoma: a North Central Cancer Treatment Group (NCCTG) study. Neuro-oncol. 2004 Nov; 6(4):376. Abstract no. TA- 26.

67. Jaeckle K, Ballman K, Schomberg P, Uhm J, Scheithauer B, Giannini C, Felton S, Brown P, Buckner J. Pillot Trial of CPT11 During RT Followed by CPT11 and BCNU in Newly Diagnosed Glioblastoma (GBM): Updated Results and Correlative Laboratory Analysis Proc Am Soc Clin Oncol. 2005; 23:117s.

68. Krishnan S, Brown P, Ballman K, Fiveash J, Uhm J, Giannini C, Geoffroy F, Nabors L, Buckner J. Phase I trial of erlotinib with radiation therapy (RT) in patients with glioblastoma multiforme (GBM) (Abstract 1513). J Clin Oncol. 2005 Jun; 23(16S part I):117s.

69. Jenkins R, Blair H, Flynn H, Passe S, Law M, Ballman K, Giannini C, Buckner J. A t (1;19)(q10:p10) mediates the combined deletions of 1p and 19q in human oligodendrogliomas Proc Am Assoc Canc Res. 2006; 57:30s.

70. Keegan M, Giannini C, Parisi JE, Lucchinetti CF, Boeve BF, Josephs KA. Adult onset, sporadic leukodystrophy with neuroaxonal spheroids mimicking cerebral MS (Abstract M-16). Ann Neurol. 2006; 60 (Suppl 10):S39.

71. Rodriguez FJ, Thibodeau SN, Jenkins RB, Showalter KV, O'Neill BP, James CD, Giannini C. MGMT promoter methylation status and expression in human glioblastoma (Abstract 1334). Lab Invest. 2006 Jan; 86(Suppl 1):287A.

72. Jenkins RB, Ballman KV, Giannini C, Arusell RM, Blair H, Flynn H, Passe S, Brown PD, Shaw EG, Buckner JC. NCCTG 94-72-53: Diagnostic and prognostic significance of a t(1;19)(q10;p10) in patients (pts) with low- grade oligodendroglioma and astrocytoma. (Abstract 1505). J Clin Oncol. 2006; 24(18s, pt 1):59s.

73. Porter Umphrey A, Giannini C, Kaufmann TJ, Lucchinetti CF, Atkinson JLD, O'Neill BP. Primary central nervous system lymphoma (PCNSL) can be diagnosed with concurrent corticosteroid (CS) use. A pilot study to determine effect of CS on the diagnosis of PCNSL (Abstract M-37). Ann Neurol. 2006; 60(Suppl 10):S44.

74. Buckner JC, Ballman K, Schaefer P, Furth AF, Giannini C, Scheithauer BW, Galanis E, Jaeckle KA. NCCTG 96-94-53: clinical variables associated with overall survival (OS), progression-free survival (PFS), 6 month progression-free survival (PFS6), immediate progression (ImmProg), and response in patients enrolled in recurrent glioma clinical trials(Abs J Clin Oncol. 2006 Jun; 24(18S):63s.

75. Vogelbaum MA, Berkey B, Peereboom D, Giannini C, Jenkins R, Suh J, Brown P, Blumenthal D, Biggs C, Mehta M. RTOG 0131: phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligodendrogliomas: relationship between 1p/19q status and progression-free survival (Abstract 1517). J Clin Oncol. 2006 Jun; 24(18S):62s.

76. Omarzai Y, Castellano-Sanchez A, Brathwaite C, Melnick S, Giannini C, Popoiti R. Low-grade leptomeningeal glioneuronal neoplasm. Mod Pathol. 2006 Sep; 19(Suppl 3):146.

77. Salvarani C, Brown RD, Calamia KT, Weigand S, Christianson T, Huston J, Meschia JF, Giannini C, Miller DV, Hunger GC. Primary central nervous system vasculitis presenting with meningeal enhancement on MRI: a newly recognized benign subset (Abstract 1160). Arthritis Rheum. 2006 Sep; 54(9 Suppl):S488.

78. O'Neill BP, Dogan A, Giannini C. EBV-asociated lymphoproliferative disorder of CNS associated with the use of mycophenolate mofetil (Abstract IM-16). Neuro-oncol. 2006 Oct; 8(4):429.

79. Kumar G, Kang CA, Giannini C. Neurosarcoidosis presenting as a cerebellar tumor: "a great mimicker" (Abstract PA-18). Neuro-oncol. 2006 Oct; 8(4):460.

80. Porter Umphrey A, Giannini C, Kaufmann T, Lucchinetti C, Atkinson JLD, O'Neill BP. Primary central nervous system lymphoma (PCNSL) can be diagnosed with concurrent corticosteroid (CS) use: a pilot study to determine whether CS affects the diagnosis of PCNSL (Abstract TA-45). Neuro-oncol. 2006 Oct; 8(4):449.


81. Jaeckle KA, Decker PA, Ballman KV, Flynn PJ, Giannini C, Scheithauer BW, Jenkins RB, Buckner JC. Progressive anaplastic transformation of infiltrative gliomas: a correlative clinicopathologic study of primary and recurrent tumors from patients treated on North Central Cancer Treatment Group (NCCTG) trials (Abstract PA-14). Neuro-oncol. 2006 Oct; 8(4):459.

82. Misra A, Smirnov I, VandenBerg S, Ware M, Hong C, Hirose Y, Mirvish E, Kapp L, Kharbanda S, Nigro J, Pan E, Prestegarden L, Yeh R, Costello J, Yates A, Pearl D, Scheithauer B, Burger P, Giannini C, Phillips H, Aldape K, Feuerstein BG. PTEN loss is a better indicator of survival than histologic grade in consensus grade 2 and 3 astrocytomas. Neuro-oncol. 2006 Oct; 8(4):461.

83. Jaeckle K, Maurer M, Reid J, Ames M, Giannini C, Moore D, Zwiebel J, Buckner J, Galanis E. Results of a Phase II Trial of Vorinostat in Patients With Recurrent Glioblastoma: Evidence of Post-Treatment Histone Acetylation in Tumor Tissue and Pharmacokinetic Analysis: North Central Cancer Treatment Group (NCCTG) Study N047B. 6th international Congress on Targeted Therapies Aug 24-26,. 2007.

84. Cady FM, Law ME, Porter-Umphrey AB, O'Neill BP, Giannini C, Remstein ED, Dogan A. The frequency of specific chromosomal abnormalities in primary central nervous system lymphoma (PCNSL) differs from systemic diffuse large B-cell lymphoma (DLBL), suggesting a distinct pathogenesis. Mod Pathol. 2007 Mar; 20(Suppl 2):235A.

85. Cady FM, Law ME, Porter-Umphrey AB, O'Neill BP, Giannini C, Remstein ED, Dogan A. The frequency of specific chromosomal abnormalities in primary central nervous system lymphoma (PCNSL) differs from systemic diffuse large B-cell lymphoma (DLBL), suggesting a distinct pathogenesis. Lab Invest. 2007 Mar; 87(Suppl 1):235A.

86. Kleinschmidt-DeMasters BK, Damek DA, Dogan A, Giannini C. EBV-driven primary CNS lymphomas (PCNSLs) are seen in Elderly Patients on a variety of immunosuppressive drugs for a variety of autoirnmune/collagen vascular diseases. FASEB J. 2007 Apr; 21(5):A391.

87. Barker JV, Scheithauer BW, Giannini C, Moss J, Farrar M, Katsarou A, Perry A, Roncaroli F. Papillary meningioma: clinicopathological features of 42 cases. Neuropathol Appl Neurobiol. 2007 Apr; 33(2):260.

88. Giannini C, Cady FM, Law ME, Porter AB, O'Neill BP, Remstein E, Dogan A. The frequency of IGH-BCL6 translocations in PCNSL is less than that seen in systemic DLBCL, suggesting a distinct pathogenesis. FASEB J. 2007 Apr; 21(5):A28.

89. Kleinschinidt-DeMasters BK, Damek DA, Dogan A, Giannini C. EBV-driven primary CNS lymphomas (PCNSLs) are seen in elderly patients on a variety of immunosuppressive drugs for a variety of autoimmune/collagen vascular diseases. J Neuropathol Exp Neurol. 2007 May; 66(5):441.

90. Giannini C, Cady FM, Law ME, Porter AB, O'Neill BP, Remstein E, Dogan A. The frequency of IGH-BCL6 translocations in PCNSL is less than that seen in systemic DLBCL, suggesting a distinct pathogenesis. J Neuropathol Exp Neurol. 2007 May; 66(5):428-9.

91. Galanis E, Jaeckle K, Maurer M, Reid J, Ames M, Giannini C, Hardwick J, Moore D, Zwiebel J, Buckner J. NCCTG Phase II Trial of vorinostat (suberoylanilide hydroxamic acid, SAHA) in Recurrent Glioblastoma Multiforme (GBM). Proc Am Soc Clin Oncol. 2007 Jun 20; 25(182).

92. Rynearson A, Giannini C, Rodriguez F, Passe S, Blanchard T, McElwain T, Marler R, Jenkins R. A subset of spontaneous canine oligodendroglial tumors share genetic similarities with human oligodendrogliomas. Neuro-oncol. 2007 Oct; 9(4):536.

93. Giannini C, Burger P, Won MH, Cairncross G, Jenkins RB, Mehta M, Curran W, Aldape K. Anaplastic oligodendroglial tumors: Refining the correlation among histopathology, 1p 19q deletion, and clinical outcome in intergroup radiation therapy oncology group trial 9402. Neuro-oncol. 2007 Oct; 9(4):548.

94. Kitange G, Carlson B, Schroeder M, Morlan B, Decker P, Ballman K, Giannini C, Sarkaria J. CD74 is preferentially overexpressed in short cultured cells from temozolomide-resistant glioblastoma xenografts and the expression in patient samples is associated with poor overall survival. Neuro-oncol. 2007 Oct; 9(4):493.

95. Rodriguez F, Perry A, Gutmann D, O'Neill B, Leonard J, Bryant S, Giannini C. Central nervous system tumors in patients with neurofibromatosis type 1: Clinicopathologic study of 100 patients. Neuro-oncol. 2007 Oct; 9(4):544.


96. Sarkaria J, Kitange G, Carlson B, Mladek A, Decker P, Schroeder M, Wu WT, Grogan P, Giannini C, Ballman K, Buckner J, James D. Methylation of discrete CpG sites within the MGMT promoter provide a superior predictor of temozolomide sensitivity in the mayo GBM xenograft panel. Neuro-oncol. 2007 Oct; 9 (4):550.

97. Schiff D, Sarkaria J, Decker P, Buckner J, Galanis E, Dancey J, Giannini C, Brown P, Wiesenfeld M, Jaeckle K. Phase I study of temsirolimus (CCI-779) and sorafenib in recurrent glioblastoma: North central cancer treatment group (NCCTG) N0572. Neuro-oncol. 2007 Oct; 9(4):518.

98. Lewis-Tuffin L, Sarkaria J, Giannini C, Tran N, Berens M, Anastasiadis P. The relationship of E-cadherin expression and Src-dependent phosphorylation of p120 catenin to gliomagenesis and invasion. Neuro-oncol. 2007 Oct; 9(4):514.

99. Raffel C, Galanis E, Giannini C, Kreofsky C, Russell S. Treatment of medulloblastoma with modified measles virus. Neuro-oncol. 2007 Oct; 9(4):562.

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Rodriguez F, Giannini C, Blair H, Wu K, Dickson D, New K, Jenkins R. Well-differentiated extraventricular neurocytoma with 1p and 19q loss in different cell clones. Neuro-oncol. 2007 Oct; 9(4):546.

Cady FM, Law ME, Giannini C, Porter AB, O'Neill BP, Decker PA, Kurtin PJ, Remstein ED, Dogan A. Del(6) (q22) and BCL6 rearrangements in primary central nervous system lymphoma (PCNSL) are indicators of an aggressive clinical course. Blood. 2007 Nov; 110(11):465A.

Rodriguez FJ, Scheithauer B, Giannini C, Bryant SC, Jenkins RB. Epithelial and pseudoepithelial morphology in glioblastoma: Comparative pathologic and molecular study of different subtypes. Mod Pathol. 2008 Jan; 21(Suppl 1):323A.

Rodriguez FJ, Scheithauer BW, Giannini C, Bryant SC, Jenkins RB. Epithelial and pseudoepithelial morphology in glioblastoma: Comparative pathologic and molecular study of different subtypes. Lab Invest. 2008 Jan; 88(Suppl 1):323A.

van Gompel JJ, Stead M, Giannini C, Meyer F, Marsh R, Lee K, So E, Cascino G, Worrell GA. Phase 1 trial: safety and feasibility of intracranial electroencephalography using hybrid electrodes containing macro and micro-electrode arrays. Epilepsia. 2008; 49(Suppl 7):383.

Jaeckle K, Anderson K, Sarkaria J, Decker P, Buckner J, Galanis E, Dancey J, Giannini C, Brown P, Wiesenfeld M, Schiff D. Phase I/II Trial of Sorafenib and CCI-779 in Patients with Recurrent Glioblastoma (GBM). 7th International Congress on Targeted Therapies. 2008.

Rodriguez FJ, Collier LS, Green LE, Bender A, Giannini C, Largaespada DA, Jenkins RB. Experimental gliomas in mice using the Sleeping Beauty (SB) transposon system: neuropathologic aspects. J Neuropathol Exp Neurol. 2008 May; 67(5):496.

Rivera AL, Pelloski CE, Giannini C, Aldape KD. Retrospective survival comparison of patients with cerebral versus cerebellar glioblastomas. J Neuropathol Exp Neurol. 2008 May; 67(5):502.

Templeton K, Kitange G, Passe S, Rynearson A, Rodriguez F, Giannini C, Jenkins RB. Candidate genes on chromosome 19q examined in chromosome 19-complemented glioma cell lines and primary tumors by Rtpcr. Neuro-oncol. 2008 Oct; 10(5):803-4.

Rodriguez EF, Scheithauer BW, Giannini C, Rynearson A, Rodriguez FJ. PTEN (10q) loss occurs in a subset of pilocytic astrocytomas with anaplastic transformation. Mod Pathol. 2009 Jan; 22(Suppl 1):1514.

Rodriguez EF, Scheithauer BW, Giannini C, Rynearson A, Rodriguez FJ. PTEN (10q) loss occurs in a subset of pilocytic astrocytomas with anaplastic transformation. Lab Invest. 2009 Jan; 89(Suppl 1):1514.

Schiff D, Brown P, Shaw E, Giannini C, Farace E, Jenkins R, Grossman S, Jaeckle K, O'Neill A. An intergroup phase III study of radiation therapy with or without temozolomide for symptomatic or progressive low grade gliomas. Neuro-oncol. 2009 Apr; 11(2):228.

Cady FM, Remstein ED, O'Neill BP, Giannini C, Porter AB, Decker PA, Dogan A. Del(6)(Q22) and Bcl6 rearrangements detected by interphase fluorescence in situ hybridization (Fish) are unfavorable cytogenetic abnormalities in immunocompetent (Ic) patients with primary CNS lymphoma (PCNSL). Neuro-oncol. 2009 Apr; 11(2):231.

Jenkins RB, Decker P, Kollmeyer T, Giannini C, Ballman K, Yang P. Differential association of chromosome 19 Snp variants with oligodendroglioma: a case-case comparison. Neuro-oncol. 2009 Apr; 11(2):227.


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Schiff D, Sarkaria J, Decker P, Buckner J, Galanis E, Dancey J, Giannini C, Brown P, Wiesenfeld M, Jaeckle K. Feasibility/tolerability results from a phase I/II study of temsirolimus (CCI-779) and sorafenib in recurrent glioblastoma: North Central Cancer Treatment Group (NCCTG) N0572. Neuro-oncol. 2009 Apr; 11 (2):232.

Donev K, Dogan A, Law M, O'Neill B, Giannini C. CNS immunodeficiency-associated lymphoproliferative disorders: clinicopathologic and cytogenetic features. J Neuropathol Exp Neurol. 2009 May; 68(5):589.

Giannini C, Roncaroli F, VanGompel J, Marsh R, Cascino G, Burger P. Cortical ependymoma: a distinct entity from angiocentric glioma? J Neuropathol Exp Neurol. 2009 May; 68(5):584-5.

Jentoft M, Giannini C, Scheithauer B, Abell-Aleff P, Rodriguez F. NF1-associated low grade gliomas: an ultrastructural study. J Neuropathol Exp Neurol. 2009 May; 68(5):583.

Van Gompel JJ, Meyer FB, Koeller K, Marsh WR, Cascino GD, Worrell GA, Giannini C. Cortical ependymoma: an unusual epileptogenic lesion. Epilepsia. 2009 Nov; 50(Suppl 11):459.

O'Neill BP, Braggio E, Remstein ED, Giannini C, Decker PA, Kurtz DM, Dogan A, Fonseca R. Brief report: array comparative genomic hybridization (ACGH) confirms fluorescent in situ hybridization (FISH) 6q deletion in poor-prognosis diffuse large b-cell, CD20-positive primary central nervous system lymphoma (PCNSL). Neuro-oncol. 2009 Dec; 11(6):915.

Rodriguez FJ, Scheithauer BW, Burger PC, Jenkins S, Giannini C. Histologic anaplasia in sporadic and NF1-associated pilocytic astrocytomas predicts unfavorable behavior. Neuro-oncol. 2009 Dec; 11(6):964.

Sarkaria JN, Galanis E, Gustafson MP, Dietz AB, Wu W, Brown PD, Uhm JH, Giannini C, Jaekle KA, Buckner JC. Effect of combined therapy with temsirolimus (CCI-779), temozolomide (TMZ), and radiation (RT) in newly diagnosed glioblastoma multiforme (GBM) patients on immune suppression: Results from NCCTG N027D. J Clin Oncol. 2010; 28(15s):183s.

Naik M, Call JA, Rodriguez FJ, Giannini C, Buckner JC, Parney IF, Laack NN. Medulloblastoma in adults: a retrospective review of prognostic factors and treatment outcomes. Int J Radiat Oncol Biol Phys. 2010; 78 (Suppl S):S261.

Laack N, Galanis E, Geoffroy F, Leinweber C, Buckner J, Anastasiadis P, Sarkaria J, Giannini C, Qin R, Wu W, Jaeckle K. Phase I/Randomized Phase II Trial of Bevacizumab in Combination With Sorafenib in Patients With Recurrent Glioblastoma Multiforme. ASCO. 2010.

Giannini C, Oelkers MM, Edwards WD, Aubry MC, Muncil MM, Mohamud KH, Sandleback SG, Nowak JM, Bridgeman AJ, Heelis P, Brown ME, Cheville JC. Maintaining clinical tissue archives and supporting human research: challenges and solutions. Mod Pathol. 2010 Feb; 23(Suppl 1):1858.

Giannini C, Oelkers MM, Edwards WD, Aubry MC, Muncil MM, Mohamud KH, Sandleback SG, Nowak JM, Bridgeman AJ, Heelis P, Brown ME, Cheville JC. Maintaining clinical tissue archives and supporting human research: challenges and solutions. Lab Invest. 2010 Feb; 90(Suppl 1):1868.

Jentoft ME, Giannini C, Rossi S, Mota R, Hoesley BL, Jenkins RB, Rodriguez FJ. Oligodendroglial tumors with desmoplasia: a case series. Mod Pathol. 2010 Feb; 23(Suppl 1):1677.

Jentoft ME, Giannini C, Rossi S, Mota R, Hoesley BL, Jenkins RB, Rodriguez FJ. Oligodendroglial tumors with desmoplasia: a case series. Lab Invest. 2010 Feb; 90(Suppl 1):1677.

Giannini C, Rodriguez F, Eberhart C, Salomao D. Choroidal findings in neurofibromatosis type 1 (NF1). J Neuropathol Exp Neurol. 2010 May; 69(5):104.

Galanis E, Jaeckle K, Anderson S, Kaufmann T, Uhm J, Giannini C, Kumar S, Northfelt D, Flynn P, Buckner J. NCCTG phase II trial of bevacizumab in combination with sorafenib in recurrent GBM. J Clinc Oncol. 2010 May; 28(15s):2018.

Johnson DR, Kimmel DW, Burch PA, Cascino TL, Giannini C, Wu WT, Buckner JC. Phase II study of octreotide in recurrent or progressive meningioma and meningeal hemangiopericytoma. Neuro-oncol. 2010 Nov; 12(Suppl 4):41.

Friday BB, Buckner J, Anderson SK, Giannini C, Kugler J, Mazurczac M, Flynn P, Gross H, Pajon E, Jaeckle K, Galanis E. Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma multiforme: a north central cancer treatment group study. Neuro-oncol. 2010 Nov; 12(Suppl 4):70.


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Pafundi DH, Brinkmann DH, Parney IF, Giannini C, Laack NN, Kemp B, Lowe V, Sarkaria JN, Yan ES. Biopsy validation of (18)F-FDOPA-PET uptake and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: preliminary results of a prospective pilot study. Int J Radiat Oncol Biol Phys. 2011; 81(S):S182.

Jentoft M, Giannini C, Cen L, Scheithauer BW, Hoesley B, Sarkaria JN, Abell-Aleff PC, Li Y, Rodriguez FJ. Phenotypic variations in NF1-associated low grade gliomas: possible role for increased MTOR activation in a subset. Mod Pathol. 2011 Feb; 24(Suppl 1):381A-2A.

Ida C, Rodriguez F, Voss J, Mc Cann B, Jenkins S, Halling K, Giannini C. Cerebellar low grade astrocytomas with diffuse growth pattern. J Neuropathol Exp Neurol. 2011 Jun; 70(6):508.

Alghamdi S, Castellano-Sanchez AA, Brathwaite C, Melnick S, Sandberg D, Olavarria G, Khatib Z, Giannini C, Burger P. Diffuse low grade leptomeningeal glio-neuronal tumor not an oligodendrogliomatosis: clinic- pathologic features of 2 cases. J Neuropathol Exp Neurol. 2011 Jun; 70(6):538.

Rice T, Zheng SC, Xiao YY, Decker PA, McCoy LS, Smirnov I, Patoka JS, Hansen HM, Wiemels JL, Tihan T, Prados MD, Chang SM, Berger MS, Pico A, Rynearson A, Voss J, Caron A, Kosel ML, Fridley BL, Lachance DH, O'Neill BP, Giannini C, Wiencke JK, Jenkins RB, Wrensch MR. Associations of glioma risk loci by IDH mutation status. Neuro-oncol. 2011 Nov; 13(3):27.

Giannini C, Bernardo MC, Menke J, Graff Radford JG, Hallemeier C, Boes CJ, Lewis M, Scheithauer BW. Intravascular mucinosis, a rare cause of cerebral infarction in cancer patients. Neuro-oncol. 2011 Nov; 13 (3):92.

Galanis E, Anderson SK, Lafky JM, Kaufmann TJ, Uhm JH, Giannini C, Kumar SK, Northfelt DW, Flynn PJ, Jaeckle KA, Buckner JC. NCCTG phase II trial of bevacizumab in combination with sorafenib (BEV/SOR) in recurrent glioblastoma (RGBM). Neuro-oncol. 2011 Nov; 13(3):62.

Eckel LJ, Keating GF, Wetjen NM, Giannini C, Wetmore C. Pilomyxoid astrocytoma of the pons. Neuro- oncol. 2011 Nov; 13(3):140.

Mihalcik SA, Jentoft M, Giannini C, Scheithauer B, Laack N. Primary tumors of the pineal region: a retrospective study of prognosis, recurrence, and the role of therapy. Neuro-oncol. 2011 Nov; 13(3):92.

Ma D, Galanis E, Schiff D, Wu W, Peller PJ, Giannini C, Brown PD, Uhm JH, McGraw S, Jaeckle KA, Flynn PJ, Buckner JC, Sarkaria JN. NCCTG N057K phase II trial of everolimus, temozolomide and radiotherapy in patients with newly diagnosed glioblastoma: a north central cancer treatment group trial. J Clin Oncol. 2012; 30(suppl; abstr 2031).

Ida CM, Minehan KJ, Jenkins SM, Laack NN, Scheithauer BW, Giannini C. Pleomorphic xanthoastrocytoma: a single institution experience. Mod Pathol. 2012 Feb; 25:431A.

Ida CM, Minehan KJ, Jenkins SM, Laack NN, Scheithauer BW, Giannini C. Pleomorphic xanthoastrocytoma: a single institution experience. Lab Invest. 2012 Feb; 92:431A.

Bosch EP, Tracy J, Goodman B, Dyck PJB, Toro C, Giannini C. Facial onset sensory and motor neuronopathy: a neurodegenerative TDP-43 proteinopathy? Neurology. 2012 Apr; 78.

Youland R, Giannini C, Parney I, Laack N. Outcomes from a large, modern series of adult low-grade gliomas from 1992 to 2011. American Journal Of Clinical Oncology-cancer Clinical Trials. 2012 Apr; 35 (2):191-2.

Jentoft M, Guo Y, Parisi J, Popescu B, Lennon V, Pittock S, Giannini C, Claudia L. Aquaporin-4 immunohistochemistry aids pathological diagnosis of neuromyelitis optica spectrum disorder. J Neuropathol Exp Neurol. 2012 Jun; 71(6):552-3.

Keating G, Eckel L, Giannini C, Wetjen N, Patton A. Desmoplastic infantile gangliogliomas - clinical features at diagnosis, peri-operatively, and ongoing followup. Neuro-oncol. 2012 Jun; 14:154.

Eckel L, Keating G, Giannini C, Wetjen N, Patton A. Desmoplastic infantile gangliogliomas - imaging appearance discretely different from previously described. Neuro-oncol. 2012 Jun; 14:142.

Ho CY, Bar E, Giannini C, Karajannis M, Zagzag D, Eberhart C, Rodriguez F. Identification of biologically relevant targets in pilocytic astrocytoma by microrna profiling. J Neuropathol Exp Neurol. 2012 Jun; 71 (6):577-8.


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Menke J, Jentoft M, Dogen A, Avent J, Miller D, Giannini C. Immunoglobulin lambda light chain deposition disease presenting as a periventricular white matter lesion. J Neuropathol Exp Neurol. 2012 Jun; 71(6):585.

Laack NN, Galanis E, Leinweber C, Buckner JC, Giannini C, Geoffroy FJ, Jaeckle KA, Sarkaria JN. Phase I randomized phase II trial of either dasatinib or placebo combined with standard chemo-radiotherapy for newly diagnosed glioblastoma multiforme (GBM): Final results of phase I study. J Clin Oncol. 2012 Jun 20; 30(18 suppl). Abstract no. 2032.

Youland R, Khwaja S, Schomas D, Brown P, Giannini C, Wetjen N, Laack N. A 40-year review of pediatric low-grade gliomas at Mayo Clinic: changes with modern imaging. Pediatr Blood Cancer. 2012 Jul; 58 (7):1081.

Salvarani C, Giannini C, Brown RD Jr, Christianson TJH, Hunder GG. A beta-related angiitis: comparison with patients with amyloid cerebral angiopathy without inflammation. Arthritis Rheum. 2012 Oct; 64 (10):S1085.

van den Bent M, Hartmann C, Preusser M, Strobel T, Dubbink HJ, Kros JM, von Deimling A, Boisselier B, Sanson M, Halling KC, Diefes KL, Aldape K, Giannini C. Interlaboratory comparison of idh mutation detection. Neuro-oncol. 2012 Oct; 14:107.

Jenkins RB, Xiao YY, Sicotte H, Decker PA, Kollmeyer TM, Hansen HM, Kosel ML, Zheng SC, Walsh KM, Rice T, Bracci P, Smirnov I, Patoka JF, Hsuang G, Wiemels JL, Tehan T, Pico AR, Prados MD, Berger MS, Caron AA, Fink SR, Halder C, Rynearson AL, Fridley BL, O'Neill BP, Giannini C, Lachance DH, Wienke JK, Eckel-Passow JE, Wrensch MR. New low frequency risk loci in the 8q24.21 (ccdc26) region are strongly associated with risk of oligodendroglial tumors and idh1/2 mutated astrocytomas. Neuro-oncol. 2012 Oct; 14:50.

Vogelbaum MA, Wang MH, Peereboom DM, Macdonald DR, Giannini C, Suh JH, Jenkins RB, Laack NN, Brackman DG, Shrieve DC, Souhami L, Mehta MP. Rtog 0131: phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligodendrogliomas: updated survival and progression free survival analysis. Neuro-oncol. 2012 Oct; 14:75-6.

Cairncross G, Wang M, Jenkins R, Shaw E, Giannini C, Brachman D, Buckner J, Fink K, Mehta M, Curran W. IDH status predicts benefit from pcv with radiation therapy in anaplastic oligodendroglioma (RTOG 9402). Int J Radiat Oncol Biol Phys. 2012 Nov 1; 84(3):S5.

Jaeckle KA, Schiff D, Anderson SK, Galanis E, Stella PJ, Flynn PJ, Sarkaria JN, Giannini C, Erickson BJ, Buckner JC. NCCTG (Alliance) N0572: A phase II trial of sorafenib and temsirolimus in recurrent glioblastoma (GBM) patients who progress following prior RT/temozolomide (TMZ) and VEGF inhibitors (VEGFi). J Clin Oncol. 2013; 31(15s):117s.

Galanis E, Sarkaria JN, Anderson SK, Wu W, Jaeckle KA, Giannini C, Buckner JC, Wen PY, Alliance for. Phase I/II trial of vorinostat combined with temozolomide (TMZ) and radiation therapy (RT) for newly diagnosed glioblastoma (GBM) (N0874-ABTC0902, Alliance): Final results of the phase I trial. J Clin Oncol. 2013; 31(15s):125s.

Giannini C, Morris JM, Hunder GG, Parisi JE, Christianson TJ, Brown RD, Salvarani C. Cerebrovascular a- beta amyloid in surgical specimens: clinicopathological correlates. Mod Pathol. 2013 Feb; 26:416A.

Giannini C, Morris JM, Hunder GG, Parisi JE, Christianson TJ, Brown RD, Salvarani C. Cerebrovascular a- beta amyloid in surgical specimens: clinicopathological correlates. Lab Invest. 2013 Feb; 93:416A.

Iankov I, Allen C, Parney I, Giannini C, Galanis E. Gene expression profiling identifies predictive markers of response to oncolytic measles virus therapy. Mol Ther. 2013 Jun; 21:S160.

Ida C, Vrana J, Rodriguez F, Jentoft M, Caron A, Jenkins S, Giannini C. Immunohistochemical analysis of BRAF V600E mutation in pleomorphic xanthoastrocytoma is an accurate detection method. J Neuropathol Exp Neurol. 2013 Jun; 72(6):562.

Warad D, Wetjen N, Giannini C, Nageswara Rao A. Primary anaplastic pilocytic astrocytoma: a brief report and literature review. Pediatr Blood Cancer. 2013 Jun; 60:S77.

Girardi H, Monville F, Poggionovo C, Catteau A, Giry M, Voos J, Jenkins RB, Mokhtari K, Peyro-Saint-Paul H, Giannini C. A new idh1/2 pcr assay for one-step detection of 12 idh1 and idh2 mutations in glioma. Eur J Cancer. 2013 Sep; 49:S213.


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Hardie JG, Kizilbash S, Buckner J, Pulley I, Giannini C, Uhm J, Laack N. Factors contributing to survival in patients with anaplastic astrocytoma: a retrospective study of patients treated at a single institution. Int J Radiat Oncol Biol Phys. 2013 Oct 1; 87(2):S104.

Salvarani C, Brown RD Jr, Christianson TJH, Huston J III, Calamia K, Giannini C, Hunder GG. Primary central nervous system vasculitis: treatment and course. Arthritis Rheum. 2013 Oct; 65:S702-3.

Girardi H, Monville F, Carpentier S, Giry M, Voss J, Jenkins R, Boisselier B, Frayssinet V, Poggionovo C, Catteau A, Mokhtari K, Sanson M, Peyro-Saint-Paul H, Giannini C. A new idh1/2 pcr assay for one-step detection of 12 idh1 and idh2 mutations in glioma. Neuro-oncol. 2013 Nov; 15:158.

Walsh KM, Decker PA, Eckel-Passow JE, Molinaro AM, Hansen HM, Rice T, Zheng SC, Kollmeyer T, Berger MS, Chang SM, Prados MD, Rynearson A, Caron A, Kosel ML, Lachance DH, O'Neill BP, Giannini C, Wiencke JK, Jenkins RB, Wrensch MR. Glioma risk snps in egfr and ccdc26 are associated with specific tumor expression signatures. Neuro-oncol. 2013 Nov; 15:91.

Ashman J, Drazkowski J, Zimmerman R, Lidner T, Giannini C, Porter A, Patel N. Intractable seizures secondary to meningioangiomatosis controlled with single fraction stereotactic radiosurgery. Neuro-oncol. 2013 Nov; 15:178.

Hardie J, Laack N, Kizilbash S, Buckner J, Giannini C, Uhm J, Parney I, Jenkins R, Decker P, Voss J. Recurrence patterns in anaplastic astrocytoma: a retrospective study of patients treated at the Mayo Clinic. Neuro-oncol. 2013 Nov; 15:181. Abstract no. RT-016.

Kurokawa C, Iankov I, Aderca I, Petell C, Middha S, Giannini C, Parney I, Galanis E. Pre-existing antiviral state can impact oncolytic infection in glioblastoma patients treated with oncolytic measles virus. Mol Ther. 2014 May; 22:S248.

Kohorst M, Warad D, Keating G, Childs S, Giannini C, Wetjen N, Nageswara Rao A. Outcomes of children and young adults with recurrent pilocytic astrocytoma treated with multiple surgical resections. Neuro-oncol. 2014 Jun; 16:63.

Giannini C, Fratkin J, Wyatt-Ashmead J, Abell Aleff P. Rhabdoid-like meningioma: a case report. J Neuropathol Exp Neurol. 2014 Jun; 73(6):608.

Jenkins RB, Decker P, Kosel M, Eckel-Passow J, Walsh KM, Smirnov IV, Caron A, Kollmeyer T, Rice T, Hansen HM, Molinaro AM, McCoy LS, Bracci PM, Cabriga BS, Marshall R, Pekmezci M, Zheng SC, O'Neill B, Buckner J, Giannini C, Perry A, Tihan T, Berger MS, Chang SM, Prados M, Wiemels J, Wiencke J, Wrensch M, Lachance D. Mutation-based molecular glioma classification: prevalence and association with germline risk snps. Neuro-oncol. 2014 Jul; 16.

Salvarani C, Brown RD Jr, Christianson TJH, Huston J III, Muratore F, Giannini C, Hunder GG. Mycophenolate mofetil in the treatment of primary central nervous system vasculitis. Arthritis & Rheumatology. 2014 Oct; 66:S1208.

Sarkaria J, Ma D, Schroeder M, Carlson B, Giannini C, Parney I. Development of a panel of patient-derived xenograft (pdx) models from brain metastases. Neuro-oncol. 2014 Nov; 16.

Ma D, Galanis E, Peller P, Ligon K, Giannini C, Sarkaria J. Genetic profiling for early everolimus sensitivity in newly diagnosed glioblastoma patients enrolled on ncctg n057k. Neuro-oncol. 2014 Nov; 16.

Eckel-Passow J, Lachance D, Walsh K, Decker P, Sicotte H, Pekmezci M, Molinaro A, Rice T, Kosel M, Smirnov I, Sarkar G, Caron A, Kollmeyer T, Giannini C, Huse J, Tihan T, Wiemels J, Wiencke J, Wrensch M, Jenkins R. Tert promoter mutation, idh mutation and 1p/19q codeletion define five glioma molecular groups with specific clinical characteristics and germline variant associations. Neuro-oncol. 2014 Nov; 16.

Carter J, Spinner R, Hawse J, Giannini C, Fritchie K. Ctnnb1 mutations and estrogen receptor beta expression in neuromuscular choristoma and associated fibromatosis. Lab Invest. 2015 Feb; 95:15A.

Carter J, Spinner R, Hawse J, Giannini C, Fritchie K. Ctnnb1 mutations and estrogen receptor beta expression in neuromuscular choristoma and associated fibromatosis. Mod Pathol. 2015 Feb; 28:15A.

Fritchie K, Jin L, Rubin B, Burger P, Oliveira A, Giannini C. Nab2-stat6 gene fusion in meningeal hemangiopericytoma and solitary fibrous tumor. Lab Invest. 2015 Feb; 95:431A.

Fritchie K, Jin L, Rubin B, Burger P, Oliveira A, Giannini C. Nab2-stat6 gene fusion in meningeal hemangiopericytoma and solitary fibrous tumor. Mod Pathol. 2015 Feb; 28:431A.


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Galanis E, Anderson SK, Anastasiadis P, Tran DD, Jeyapalan SA, Anderson DM, Kaufmann TJ, Giannini C, Buckner JC, Schiff D. Ncctg n0872 (alliance): a randomized placebo- controlled phase ii trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma (gbm). J Clin Oncol. 2015 May 20; 33 (15).

Laack NN, Galanis E, Anderson SK, Leinweber C, Buckner JC, Giannini C, Geoffroy FJ, Johnson DR, Lesser GJ, Jaeckle KA, Sarkaria JN. Randomized, placebo-controlled, phase ii study of dasatinib with standard chemo-radiotherapy for newly diagnosed glioblastoma (gbm), ncctg n0877 (alliance). J Clin Oncol. 2015 May 20; 33(15).

Laack NN, Galanis E, Anderson SK, Leinweber C, Buckner JC, Giannini C, Geoffroy FJ, Johnson DR, Lesser GJ, Jaeckle KA, Sarkaria JN. Randomized, placebo-controlled, phase ii study of dasatinib with standard chemo-radiotherapy for newly diagnosed glioblastoma (gbm), ncctg n0877 (alliance). J Clin Oncol. 2015 May 20; 33(15).

Chang SM, Zhang PX, Cairncross JG, Gilbert MR, Bahary JP, Dolinskas C, Aldape KD, Chakravarti A, Schiff D, Jaeckle KA, Brown PD, Barger G, Werner-Wasik M, Shih HA, Brachman D, Penas-Prado M, Robins HI, Belanger K, Schultz CJ, Mehta MP. Results of nrg oncology/rtog 9813: a phase iii randomized study of radiation therapy (rt) and temozolomide (tmz) versus rt and nitrosourea (nu) therapy for anaplastic astrocytoma (aa). J Clin Oncol. 2015 May 20; 33(15).

Leach CB, Jaeckle KA. What do young adults with cancer indicate as their primary need for financial grant support? J Clin Oncol. 2015 May 20; 33(15).

Vizcaino MA, Giannini C, Rodriguez F. Braf (v600e) analysis by immunohistochemistry in 204 low-grade glial and glioneuronal tumors. J Neuropathol Exp Neurol. 2015 Jun; 74(6):620-1.

Giannini C, Ligon K, Miller R, Tollefson H, Korinek M, Holmes D, Jenkiins S, Galanis E, Buckner J. Central pathology review by whole slide imaging in glioblastoma clinical trials. J Neuropathol Exp Neurol. 2015 Jun; 74(6):595.

Yamada S, Kipp B, Voss J, Giannini C, Raghunathan A. Combined idh1-r132h mutant "infiltrating astrocytoma/pleomorphic xanthoastrocytoma'' with concurrent braf v600e mutation. J Neuropathol Exp Neurol. 2015 Jun; 74(6):607.

Vaubel R, Chen S, Raleigh D, Link M, Chicoine M, Barani I, Dahiya S, Perry A, Giannini C. Meningiomas with focal rhabdoid features lacking other histologic features of malignancy: a study of 37 cases. J Neuropathol Exp Neurol. 2015 Jun; 74(6):591.

Ida C, Butz M, Jenkins R, Sarkaria J, Kitange G, Giannini C, Kipp B. Mgmt promoter methylation testing in glioblastoma: detection of a heterogeneous methylation process. J Neuropathol Exp Neurol. 2015 Jun; 74 (6):594-5.

Nauen D, Haley L, Lin MT, Perry A, Giannini C, Burger P, Rodriguez F. Molecular cytogenetic analysis of pediatric oligodendrogliomas. J Neuropathol Exp Neurol. 2015 Jun; 74(6):621.

Salvarani C, Morris JM, Giannini C, Christianson TJH, Brown RD Jr, Hunder GG. Imaging findings of cerebral amyloid angiopathy, abeta-related angiitis (abra) and cerebral amyloid angiopathy-related inflammation: a single institution 25 year experience Arthritis & Rheumatology. 2015 Oct; 67: (Suppl 10).

Elwood K, Warad D, Daniels D, Giannini C, Laack N, Khan S, Raghunathan A, Vilmarie R, Nageswara Rao A. Thalamic glial tumors in children and adolescents: a single institution experience. Pediatr Blood Cancer. 2015 Nov; 62:S280.

Arnett A, Zhang Y, Seaberg M, Pafundi D, Brinkmann D, Giannini C, Laack N. Utilization of 18f-dopa-pet imaging for neurosurgical planning and target delineation in the treatment of pediatric gliomas. Pediatr Blood Cancer. 2015 Nov; 62:S271.

Paolini M, Kipp BR, Sukov WR, Raghunathan A, Barr Fritcher EG, Aranda DM, SantaCruz K, Al-Dandan S, Fisher P, McDonald W, Bondurant CP, Darkow GV, Giannini C, Parisi JE, Jentoft ME. Atypical teratoid/rhabdoid tumors (at/rts) of the sellar region in adults: characterization of five cases Laboratory Investigation. 2016 Feb; 96:435A.


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Paolini M, Kipp BR, Sukov WR, Raghunathan A, Barr Fritcher EG, Aranda DM, SantaCruz K, Al-Dandan S, Fisher P, McDonald W, Bondurant CP, Darkow GV, Giannini C, Parisi JE, Jentoft ME. Atypical teratoid/rhabdoid tumors (at/rts) of the sellar region in adults: characterization of five cases Modern Pathology. 2016 Feb; 29:435A.

Thomas C, Hovestadt V, Schrimpf D, Johann P, Bens S, Oyen F, Vogel H, Giangaspero F, Antonelli M, Riemenschneider M, Bernardo MC, Giannini C, Din NU, Perry A, Keyvani K, van Landeghem F, Sumerauer D, Hauser P, Capper D, Korshunov A, Jones DTW, Pfister S, Schneppenheim R, Siebert R, Fruhwald MC, Kool M, Hasselblatt M. Atypical teratoid rhabdoid tumors and poorly differentiated chordomas: distinct molecular entities with smarcb1/ini1 loss and dismal prognosis Neuro-oncology. 2016 Jun; 18:3.

Nageswara Rao A, Kohorst M, Warad D, Ligon K, Daniels D, Raghunathan A, Sinai C, Ligon A, Giannini C. Braf alterations in pediatric pilocytic astrocytomas with recurrences/progression Neuro-oncology. 2016 Jun; 18:83-4.

Kratz A, Sahm F, Schrimpf D, Jones DT, Reuss D, Kolsche C, Huang K, Wefers AK, Hovestadt V, Gramatzki D, Felsberg JR, Koch A, Thomale U, Reifenberger G, Becker A, Hans V, Prinz M, Staszewski O, Acker T, Dohmen-Scheufler H, Hartmann C, Mueller W, Tuffaha MSA, Paulus W, Hess K, Brokinkel B, Schittenhelm J, Monoranu C, Kessler AF, Buslei R, Deckert M, Mawrin C, Kohlhof P, Hewer E, Olar A, Rodriguez F, Giannini C, NageswaraRao AA, Weller M, Pohl U, Brandner S, Pfister SM, von Deimling A, Capper D. Combined alterations in mapk pathway genes, cdkn2a/b and atrx characterize anaplastic pilocytic astrocytoma Neuro-oncology. 2016 Jun; 18:63.

Cupit M, Kohorst M, Warad D, Li Z, Rodriguez V, Giannini C, Laack N, Daniels D, Nageswara Rao A. Quality of life outcomes in children with pilocytic astrocytomas: a cross-sectional study Neuro-oncology. 2016 Jun; 18:148.

Vaubel R, Caron A, Yamada S, Rodriguez F, NageswaraRao A, Lachance D, Parney I, Jenkins R, Giannini C. Recurrent genetic alterations in classic and anaplastic pleomorphic xanthoastrocytoma: characterization of 36 cases by snp array Journal Of Neuropathology And Experimental Neurology. 2016 Jun; 75: (6)593.

Paolini M, Kipp B, Sukov W, Raghunathan A, Fritcher EB, Aranda D, SantaCruz K, Al-Dandan S, Fisher P, McDonald W, Darkow GV, Bondurant C, Giannini C, Parisi J, Jentoft M. Sellar atypical teratoid/rhabdoid tumors (at/rts): review of reported cases Journal Of Neuropathology And Experimental Neurology. 2016 Jun; 75: (6)611.

Brown PD, Ballman KV, Cerhan JH, Anderson SK, Carrero XW, Whitton AC, Greenspoon J, Parney I, Laack, Ashman J, Bahary JP, Hadjipanayis CG, Urbanic J, Barker FG, Farace E, Khuntia D, Giannini C, Buckner JC, Galanis E, Roberge D. NCCTG N107C/CEC.3 (Alliance/Canadian Cancer Trials Group): Phase III Trial of Post-Operative Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease International Journal of Radiation Oncology*Biology*Physics.2016;96:(2 supp)S1-268.

Bond KM, Hughes JD, Porter AL, Orina JN, Fang SN, Giannini C, Parney IF. Adult pilocytic astrocytoma: an institutional series and systematic literature review for extent of resection and recurrence Neuro-oncology. 2016 Nov; 18:163.

Brown PD, Ballman KV, Cerhan J, Anderson SK, Carrero XW, Whitton AC, Greenspoon J, Parney IF, Laack NN, Ashman JB, Bahary JP, Hadjipanayis CG, Urbanic JJ, Barker FG, Farace E, Khuntia D, Giannini C, Buckner JC, Galanis E, Roberge D. N107c/cec.3: a phase III trial of post-operative stereotactic radiosurgery (srs) compared with whole brain radiotherapy (wbrt) for resected metastatic brain disease International Journal Of Radiation Oncology Biology Physics. 2016 Dec 1; 96: (5)937.

Rossi S, Toffolatti L, Signori R, Boscato E, Zanatta L, Volpato AG, Valori L, Cacciatore M, Peciarolo A, Ascani S, Pizzato C, Grotto P, Marton E, Giannini C, Longatti P. Clinicopathological features of c11orf95- rela positive ependymomas in a series of adult and young patients with long follow-up Laboratory Investigation. 2017 Feb; 97: (Suppl 1)436A.

Rossi S, Toffolatti L, Signori R, Boscato E, Zanatta L, Volpato AG, Valori L, Cacciatore M, Peciarolo A, Ascani S, Pizzato C, Grotto P, Marton E, Giannini C, Longatti P. Clinicopathological features of c11orf95- rela positive ependymomas in a series of adult and young patients with long follow-up Modern Pathology. 2017 Feb; 30: (Suppl 2)436A.

Swanson A, Giannini C, Folpe A, Van Dyke D, Vaubel R. Low-grade fibromyxoid sarcoma arising within the median nerve Journal Of Neuropathology And Experimental Neurology. 2017 Jun; 76: (6)508.


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Paolini M, Krauss W, Giannini C, Clarke M, Raghunathan A. Subependymomas of the spinal cord: a report of four cases Journal Of Neuropathology And Experimental Neurology. 2017 Jun; 76: (6)518.

Youland RS, Pafundi DH, Brinkmann DH, Lowe VJ, Morris JM, Hunt CH, Kemp BJ, Giannini C, Parney IF, Laack NN. Prospective trial utilizing 3,4-dihydroxy-6-[18f]-fluoro-l-phenylalanine (18f-dopa) pet-guided biopsy and resection of recurrent glioma International Journal Of Radiation Oncology Biology Physics. 2017 Oct 1; 99 (2 Suppl):E117

Burgenske D, Eckel-Passow J, Decker P, Kosel M, Youland R, Remonde D, Kollmeyer T, Sicotte H, Caron A, Giannini C, Lachance D, Jenkins R, Sarkaria J. Clinical and molecular analyses of long-term survivors of glioblastoma Neuro-Oncology. 2017 Nov; 19(Suppl 6):98

Johnson D, Giannini C, Caron A, Lachance D, Kaufmann T. Presence and pattern of calcification on ct strongly predict glioma subtype Neuro-Oncology. 2017 Nov; 19(Suppl 6):152-3

Eckel-Passow JE, Decker PA, Hughes EG, Kollmeyer T, Kosel ML, Burgenske DM, Sarkaria JN, Giannini C, Kipp BR, Lachance DH, Jenkins RB. Clinical sensitivity and specificity of Illumina methylation array for classifying adult gliomas into WHO groups Society for Neuro-Oncology Annual Scientific Meeting.2017;


Letters

1. Giannini C, Scheithauer BW. Villonodular synovitis - response. J Neurosurg. 1996 Sep; 85(3):528.

2. Rodriguez FJ, Brown RD, Mohr JP, Piepgras DG, Thielen K, Blume RS, Connolly H, Petty G, Giannini C. Embolic atrial myxoma with neoplastic aneurysm formation and haemorrhage: a diagnostic challenge. Neuropathol Appl Neurobiol. 2006 Apr; 32(2):213-6. PMID:16599950 DOI:10.1111/j.1365-2990.2006.00721.x

3. Rossi S, Rodriguez F, Dei Tos, Di Paola, Bendini M, Jenkins R, Giannini C. Re: Diffuse leptomeningeal glioneuronal tumors: a new entity? Brain Pathol. 2009 Oct; 19(4):745; author reply 746. PMID:19744049 DOI:10.1111/j.1750-3639.2009.00330.x

4. Keegan BM, Giannini C, Pittock SJ. Reply: A new case of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) with initial normal magnetic resonance imaging. Brain. 2011 Aug; 134:e183.

5. Menke JR, Jentoft ME, Dogan A, Avent JM, Miller DV, Giannini C. Periventricular white matter immunoglobulin lambda light chain deposition disease diagnosed by proteomic analysis. Acta Neuropathol. 2012 Aug; 124(2):293-5. Epub 2012 Jul 04. PMID:22760528 DOI:10.1007/s00401-012-1008-2

6. Giannini C, Fratkin JD, Wyatt-Ashmead J, Aleff PC. Rhabdoid-like meningioma with inclusions consisting of accumulations of complex interdigitating cell processes rather than intermediate filaments. Acta Neuropathol. 2014; 127(6):937-9. Epub 2014 Apr 2 PMID:24691783 DOI:10.1007/s00401-014-1273-3

7. Giannini C, Spengel KC, Abell Aleff PC, Rivera M, Wald JT. 24-Year-Old Woman with Recent Onset Back Pain. Brain Pathol 2015 Nov; 25 (6):786-7 PMID:26526948 DOI:10.1111/bpa.12324

8. Hasselblatt M, Thomas C, Hovestadt V, Schrimpf D, Johann P, Bens S, Oyen F, Peetz-Dienhart S, Crede Y, Wefers A, Vogel H, Riemenschneider MJ, Antonelli M, Giangaspero F, Bernardo MC, Giannini C, Ud Din N, Perry A, Keyvani K, van Landeghem F, Sumerauer D, Hauser P, Capper D, Korshunov A, Jones DT, Pfister SM, Schneppenheim R, Siebert R, Fruhwald MC, Kool M. Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis. Acta Neuropathol 2016 Jul; 132 (1):149-51 Epub 2016 Apr 11 PMID:27067307 DOI:10.1007/s00401-016-1574-9

9. Vaubel R, Giannini C, Rodriguez F, Burger PC, Dahiya S, Perry A. Rhabdoid meningioma: grading and prognostic significance of this uncommon variant reply Journal Of Neuropathology And Experimental Neurology 2017 May; 76 (5):415-6

10. Pratt D, Natarajan SK, Banda A, Giannini C, Vats P, Koschmann C, Mody R, Chinnaiyan A, Venneti S. Circumscribed/non-diffuse histology confers a better prognosis in H3K27M-mutant gliomas. Acta Neuropathol 2018 Feb; 135 (2):299-301 Epub 2018 Jan 04 PMID:29302777 DOI:10.1007/s00401-018-1805-3

11. Louis DN, Wesseling P, Paulus W, Giannini C, Batchelor TT, Cairncross JG, Capper D, Figarella-Branger D, Lopes MB, Wick W, van den Bent M. cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC). Acta Neuropathol 2018 Mar; 135 (3):481-484 Epub 2018 Jan 25 PMID:29372318 DOI:10.1007/s00401-018-1808-0

12. Louis DN, Giannini C, Capper D, Paulus W, Figarella-Branger D, Lopes MB, Batchelor TT, Cairncross JG, van den Bent M, Wick W, Wesseling P. cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant. Acta Neuropathol 2018 Mar 1 Epub 2018 Mar 01 PMID:29497819 DOI:10.1007/s00401-018-1826-y

Miscellaneous

1. Wenger DE, McLeod RA, Krecke KN, Giannini C, Scheithauer BW. Pigmented villonodular synovitis of the spine. (Scientific Exhibit). Radiologic Society of North America. Chicago, IL, 1995 Nov.

Forthcoming

1. Akkus A, Ali I, Sedlar J, Kline TL, Parney IF, Giannini C, Erickson BJ. Predicting 1p19q Chromosomal Deletion of Low-Grade Gliomas from MR Images using Deep Learning IEEE Transactions on Image Processing (submitted)

2. Buckner JC, Giannini C, Eckel-Passow J, Lachance DH, Parney IF, Laack NN, Jenkins RB. Low-grade Glioma Management Utilizing Molecular Diagnostics Nature Reviews Neurology (submitted)


3. McKenzie G, Howe B, Giannini C, Rose P, Wenger DE. Primary intra-osseous psammomatous melanotic schwannoma of the sacrum: A rare lesion with intra-lesional fat Skeletal Radiology

* Indicates that the primary author was a mentee of this author.

Documents

Curriculum Vitae and Bibliography Caterina Giannini, MD · Personal Information Curriculum Vitae and Bibliography Caterina Giannini, MD Place of Birth: Citizenship: Work Address: