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Prof. Charles O. A . Omwandho, Ph.D., Curriculum Vitae CURRICULUM VITAE Charles Odero Aono Omwandho B.Sc. Hons, M.Sc. (Nairobi), Ph.D. (Newcastle, Australia) Associate Professor of Biochemistry Department of Biochemistry University of Nairobi P. O. Box 30197, Nairobi, Kenya Phone: +254-020-4442534, Fax 254-020-4442841 Email: [email protected] //[email protected]

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Page 1: CURRICULUM VITAE · Prof. Charles O. A. Omwandho, Ph.D., Curriculum Vitae 2 2. TABLE OF CONTENTS Header 001 Table of contents 002 Personal Information 003 Educational background 003

Prof. Charles O. A . Omwandho, Ph.D., Curriculum Vitae

CURRICULUM VITAE

Charles Odero Aono Omwandho B.Sc. Hons, M.Sc. (Nairobi), Ph.D. (Newcastle, Australia)

Associate Professor of Biochemistry

Department of Biochemistry

University of Nairobi

P. O. Box 30197, Nairobi, Kenya

Phone: +254-020-4442534, Fax 254-020-4442841

Email: [email protected] //[email protected]

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2. TABLE OF CONTENTS Header 001 Table of contents 002 Personal Information 003 Educational background 003 Scholarships and Awards 04-5 Additional Honours 006 Employment record/Administrtive Responsibilities 06-7 University Teaching Experience 008 Internal and External Examinations 09-12 Reviews to International Journals 012 Services to University of Nairobi Committees 13-14 Current Research Interests 014 Supervision of Honours and graduate Students, UoN & elsewhere 15-17 Publications 18-25 Selected Workshops attended/facilitated 25-26 Invitations as Visiting Scientist/ Professor /Consultant 26-27 Ongoing scientific responsibilities (global) 027 Contributions to Scientific leadership 27-29 Membership to professional associations 029 Grants, material and cash donations received 29-30 Referees 031

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1. PERSONAL INFORMATION

Date and Place of Birth: December 5, 1961 - Kisumu, Kenya

Nationality: Kenyan

Marital Status: Married with 3 children

Languages Spoken: English, Swahili, Luo

3. EDUCATIONAL BACKGROUND 1992 – 1996: University of Newcastle Australia:

Doctor of Philosophy (Ph.D), in Reproductive Immunochemistry; Thesis Title: “Ovine Placental Immunologlobulins: Purification, Partial Characterization and Some in vitro Biological Activities”.

1986 – 1989: University of Nairobi. Master of Science (M.Sc.) in Biochemistry, Thesis Title: “Effects of Albendazole Therapy on Serum Proteins and Leukocyte Counts of Hydatid Patients”

1983 – 1986: University of Nairobi. Bachelor of Science (B.Sc.)

Upper 2nd Class Honours (Biochemistry and Zoology). 1980- 1981: High School (Maranda High School, Bondo) 1976-1979: Secondary Education (Kisumu Day Sec. School, Kisumu)

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4. SCHOLARSHIPS AND AWARDS WON

a) Scholarships/Awards 1983 – 1986: Kenya Government scholarship to pursue B.Sc

Degree at the University of Nairobi, Kenya

1986 – 1987: University of Nairobi scholarship to pursue M.Sc degree in Biochemistry at the University of Nairobi, Kenya.

1989: German Academic Exchange (DAAD) scholarship to complete Master of Science (M.Sc.) Degree at the University of Nairobi, Kenya.

Sept. 1990: International Cell Research Organization (ICRO)/UNESCO

scholarship to undertake a one month training course on Biological membranes and Liposomes at Shangai Institute of Biochemistry and Molecular Biology, Shanghai, China

Dec 1991: Japanese government (Monbusho) scholarship to pursue

Ph.D at Tokushima University, Japan: scholarship declined in favour of one from Australia (See below).

Dec 1991: Australian Government “Equity and Merit” scholarship to

pursue Ph.D at the University of Newcastle, New South Wales, Australia.

Aug 1994: World Placental associations fellowship to attend a conference on “Placenta” in Sydney, Australia.

July 1996: World Placental Associations Fellowship to attend a conference on “Trophoblast” in Banff, Canada.

May-July 1999: German Academic Exchange (DAAD) fellowship to carry out short-term research at Bielefeld Institute of Reproductive Medicine, Bielefeld, Germany.

May 2001: International Programme for Chemical Sciences (IPICS)

Fellowship to attend an intensive course in structural Biology and Bionformatics at Buea University, Cameroon.

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August 2001: International Programme for Chemical Sciences (IPICS) Fellowship to attend an intensive course in Structural Biology and Bioinformatics at Lunds University, Sweden.

November 2001: Federation of African Societies for Biochemistry and Molecular biology (FASBMB) / International Union of Biochemistry and Molecular Biology (IUBMB) fellowship to attend and present a paper titled” Is ovine placental IgG toxic to human natural killer cells?” at the International Union of Biochemistry and Molecular Biology/ and The South African Societies for Biochemistry and Molecular Biology special meeting on “The Biochemical and Molecular basis of disease” at Cape Town University, South Africa

May – July 2003: German Academic Exchange (DAAD) Fellowship to carry out short-term research at Justus Liebig University, Giessen, Germany.

Oct, 1, 2005 - March, 31, 2006: A six month Konrad/NIH Fellowship through Prof. Joan S.

Hunt( Host) , a University Distinguished Professor and Vice Chancellor for Research, Kansas University Medical School, U.S.A.to take a six month Sabbatical as a visiting Professor to department of Anatomy and Cell Biology, Kansas University Medical School, Kansas, U.S.A.

b) Special Awards

July 1996: Kodak Eastman Young Investigator Award Banff,Canada)

in recognition of my contribution to reproductive medicine and to present a paper titled“Re-association of human and ovine placental eluate immunoglobulins with acidified trophoblast vesicles

January 2006: Invitation Fellowship (10 months) by Japanese Society for

Promotion of Science JSPS. The ten-month award (1st December 2006 to 31st September 2007) was taken at the National Institute of Animal Health, Tsukuba, Japan.

August 2008: Special Award of Alexander von Humboldt foundation

fellowship for a six month research stay at Justus Liebig University of Giessen, Germany

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Additional Honours

May 2010: Nominated to be considered for inclusion in the Who’s who in the World by Who’s who selection Committee of the Marquis Who’s who, 890 Mountain Ave, New providence, NJ, USA 07974, 908-673-1000

5. EMPLOYMENT RECORD

Oct 16’ 2006 to date: Associate Professor, Department of Biochemistry,

University of Nairobi, Kenya.

Nov 13 ‘02–Oct 15’ 2006: Senior Lecturer, Department of Biochemistry, University of Nairobi, Kenya.

Jan 1998 – Nov 12’ 2002: Lecturer, Department of Biochemistry, University of Nairobi, Kenya.

April 1993 – Sept 1996: Part time Research Assistant to Professor T. K. Roberts, Biological Sciences Department, University of Newcastle, Australia.

July 1995: Part time (relief) Lecturer of Immunology to third year B.Sc. Students at the University of Newcastle, Australia.

April 1992 – Sept 1996: Part time Tutor in Biochemistry, Immunology and Cell Biology, University of Newcastle, New South Wales, Australia

Aug 1991 – Jan 1998: Tutorial Fellow, Department of Biochemistry, University of Nairobi, Kenya.

Oct 1989 – July 1991: Graduate Assistant, Biochemistry Department, University of Nairobi, Kenya.

Sept. 1986 – Nov 1986: Graduate Teacher at Dagoretti High School, Nairobi, Kenya

Jan 1982 – Sept 1983: Untrained High School Teacher at Ogada Secondary School, Kisumu.

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6. ADMINISTRATIVE RESPONSIBILITIES

March 2009 to date: Associate Dean, Pre-clinical Departments: Schools of

Medicine, Pharmacy, Dental and Nursing Sciences, University of Nairobi

Higher Acting Capacities

31st December- 22 February 2010: Acting Dean, School of Medicine, University of Nairobi

6-15 June 2009: Acting Dean, School of Medicine, University of Nairobi

Acted Chairman, Department of Biochemistry, University of Nairobi on the following dates

June 24 - 29 2004

July 31 - August 6 2004

Jan 17 - 22 Jan 2005

March 22 - March 24 2005

Duties included Supervision of day- to day running of departmental affairs including

Teaching and examinations

Attending to administrative meetings at the Schools of Medicine, Dental

Sciences, Pharmacy, Veterinary Science, Agriculture and Science)

Approving purchasing orders for laboratory and departmental animal house

consumables

Attending appointment committee meetings at the College of Biological and

Physical Sciences and College of health Sciences

Receiving departmental visitors including the Principal and Vice Chancellor on

which occasions I would conduct a guided tour of the department to show

research facilities, ongoing research and highlight departmental strains with

regard to facilities required for optimal departmental function.

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7. UNIVERSITY TEACHING EXPERIENCE

Taught the following: - a) Combined MB.ChB I, BDS I and B.Pharm I

Commonly taught courses

Introduction to Biomolecules

Cell structure and Organelle functions

Amino acid structure and Chemical reactions

Peptide bond formation

Protein structure and Function

Protein Purification techniques

Biological membranes

Introduction to Enzymology and Enzyme Kinetics Carbohydrate and Lipid metabolism

Biochemistry of Vitamins

Biochemical endocrinology

Drug metabolism

Clinical Enzymology

Integration of Metabolism

b) B.Sc III Biochemistry

Molecular Immunology

Biochemical techniques and Instrumentation

c) Master of Science in Biochemistry

Protein structure in relation to function MB503

Biochemical techniques and Instrumentation MB504

Molecular Immunology MB507.

d) Masters of medicine in Psychiatry

Neurochemistry

e) Master of Science in Reproductive Biology

Reproductive Immunology

f) Supervision of B.Sc. III projects g) Coordination of Academic Programmes:

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Assistant course co-ordinator, combined MB.Ch.B I, BDS I and B.Pharm. I (1998-2001)

Course co-ordinator, Combined MB.ChB I, BDS I and B.Pharm I (2002-2006)

8. INTERNAL AND EXTERNAL EXAMINATIONS

a) Regular Examinations at the University of Nairobi I have examined all the courses taught at the University of Nairobi (see No. 6 above)

b) Higher degree theses examined at the University of Nairobi Examined numerous M.Sc. and Ph.D. theses and sat on many Post-graduate Examination Boards at the University of Nairobi, Kenya as shown below: -

1998: Served as a member of the Examination Board during the Oral defense and supervised correction for Ms. Jemimah A. Oduma’s Ph.D thesis titled “the effect of Heptchlor-organo Chlorine Pesticide on the reproductive Perfomance of Female Sprague Dawley Rats.” Degree awarded in November 1998: Department of Animal Physiology, University of Nairobi, Kenya.

1999: Served as a member of the Examination Board during the Oral Examination (Defense) of Mr. Nicholas k. Gikonyo’s Ph.D thesis titled “Semiochemical Basis of Feeding Preferences on water buck kobus Defassa Buffallo Syncerus caffer and ox, by some Glossina morsitans group of Tsetse flies.” Degree awarded in November 1999: Department of Chemistry, University of Nairobi, Kenya.

2000: Served as Internal examiner and a member of the Examination board for John Munderu Muchiri’s M.Sc thesis titled “Elution and partial Characterisation of Immunoglobulins bound to Goat Placenta.” Degree awarded in November 2000: Department of Biochemistry, University of Nairobi, Kenya.

2000: Served as a member of the Examination Board during the Oral Examination (Defense) of Mr. K. R. Oluoch’s M.Sc thesis titled: “Identification of DNAs located on a sub-telomeric fragment to Theileria parva genome.” Degree awarded in November 2000: Department of Biochemistry, University of Nairobi, Kenya.

2001: Served as Internal Examiner and a member of the Examination board for Mr. Washington Ochieng’s M.Sc. thesis, titled, “Pathogenesis and Immune Responses in HIV-1 infected infants and children in Kenya.” Degree awarded in November 2001: Department of Biochemistry, University of Nairobi, Kenya.

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2001: Served as board member during the Oral Examination (Defense) of Amos Mr. Kungu Mbugua’s M.Sc thesis titled “Isolation and characterization of Trypanosoma Congolense gene encoding an antigen recognised by infective serum from Cape buffalo.” Degree awarded in November 2001: Department of Zoology, University of Nairobi, Kenya.

2001: Served as internal Examiner for Mr. Moses Sichangi’s M.sc thesis titled “Analysis of Endogenous Retrovirus-like particle expression in normal male olive baboon (papio Anubis) reproductive tissues.” Degree awarded in November 2001: Department of Animal physiology, University of Nairobi, Kenya.

2002: Served as a member of the examination board during the Post humous examination of the late W. Njoroge’s MSc thesis titled “Early diagnosis and vertical transmission of HIV-1 in children born to HIV-1 seropositive mothers in rural Western Kenya. Degree awarded posthumously in November 2002: Department of Biochemistry, University of Nairobi, Kenya.

2002: Served as internal examiner for Daudi K. Langat’s Ph.D thesis titled “Molecular characterization of Paan-AG, An HLA-G_like gene expressed in baboon (Papio anubis) Placenta”. Degree awarded in November 2002: Department of Animal Physiology, University of Nairobi, Kenya

2003: Served as internal examiner for PhD thesis for Ms Abubakar Laila Uweso titled “Molecular characterization of the lectin-trypsin complex from midgut of the testse fly Glossina Fuscipes.” Degree awarded in November 2003: Department of Biochemistry, University of Nairobi, Kenya

2004: Served as internal examiner for MSc thesis of Fredrick Onyango Onono titled “T-cell responses in the cattle immunised with a prototype anti-sporozoite sub-unit vaccine against theileria parva Degree awarded in May 2004: Department of Biochemistry, University of Nairobi, Kenya

2004: Served as an internal examiner for the MSc. Thesis of Humphrey K. Njaanake titled “Comparison of the effects of two praziquantel doses versus two metrifonate doses in Schistosoma haematobium (Mazeras strain) infection in hamsterns” degree awarded in November 2004: Department of Zoology, Univeristy of Nairobi, Kenya

2005: Served as a board member during the Oral defence of Ph.D thesis of Mutahi W. titled, “comparison of Praziquantel and metriofonate doses in field trials in school children in Machakos and Mwea Districts of Kenya”. Degree awarded in February 2005: Department of Zoology, University of Nairobi, Kenya

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2005: Served as Internal Examiner for an M.Sc. thesis of Patrick Onyango Ogola titled “Hormonal correlates and effects of maternal life History traits on natal dispersal among male yellow baboons, Papio Cynocephalus in Amboseli National Park”. Degree awarded in November 2005: Department of Animal Physiology, University of Nairobi, Kenya

2005: Served as internal examiner for M.Sc. of George Otieno Mala titled “Quantitation and partial characterization of placental bound immunoglobulin-G (IGg) in normal and pathological human placentae.” Degree awarded in November 2005: Department of Biochemistry, University of Nairobi, Kenya

2005: Served as internal examiner for M.Sc. thesis of Carolyne Wasonga titled “Effects of edible Basidiomycetes fruit body extracts on induced liver tumor in mice” . Degree warded in November 2006: Department of Biochemistry, University of Nairobi, Kenya

2006: Served as internal examiner for M.Sc. thesis of Mr. Ezekiel Onyonka Mecha titled “Natural killer cells and selected enzyme /metabolite profiles in HIV infection and progression to AIDS. Degree to be awarded in November 2007: Department of Biochemistry, University of Nairobi, Kenya

2007: Served as a board member during the Oral defence of M.Sc. thesis of Ms. Margaret Oeph’s. titled, “Isolation of soil actinomyecetes from different sites and screening for their anti-microbial activity” Degree to be awarded in 2008: Department of Botany, University of Nairobi, Kenya

2009: Served as a board member during the Oral defence of Mercy Wanjiku Kamau’s M.Sc. thesis. titled, “In vitrostudy of the effect of organic extracts of Enzoy in isolated rabbit heart and jejunum” Degree to be awarded in December 2009: Department of Medical Physiology, University of Nairobi, Kenya

2010: Served as a board member during the Oral defence of Isaac Chogii’s M.Sc. thesis. titled, “Potential of synthetically modified surface exudates as anti-plasmodial Principals” Degree to be awarded in September 2010: Department of Chemistry, University of Nairobi, Kenya

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c) External Examinations at Other Universities

i) Regular

July 2006: Appointed External Examiner in Biochemistry, department of Pre-clinical Sciences, Kenyatta University, Kenya (ii) June 2008: Appointed External Examiner; department of Biochemistry, Makerere University, Kampala, Uganda (iii) February 2010: Appointed External Examiner; School of Biomedical Sciences, Maseno University, Kenya

ii) Theses 2005: Appointed External Examiner by The University of Newcastle, Australia to examine the M.Sc. thesis of Mr. Hai LIN titled “ Delta haemolysin Production of long-term Staphylococcus epidermidis cultures. Degree awarded in 2005: Biological Sciences Department, University of Newcastle, Callaghan, NSW 2308, Australia 2008: Appointed External Examiner by Kenyatta University, Kenya to examine M.Sc. thesis of Mr. Kang’ethe Stanley Kamwati titled “Role of Cryptosporidium as a cause of diarrhoea among children attending Mathare North Health Centre, Nairobi”. Degree awarded in 2008: Department of Biochemistry and Biotechnology, Kenyatta University, Kenya 2008: Appointed External Examiner by Kenyatta University, Kenya to examine M.Sc. thesis of Mr. Martin Ndonga Matu titled “Lactobacillus ssp colonization after treatment for bacterial vaginosis and their inhibitory potential to the BVA associated Bacteria”. Degree to be awarded in 2008: Department of Biochemistry and Biotechnology, Kenyatta University, Kenya 2008: Appointed External Examiner by Kenyatta University, Kenya to examine M.Sc. thesis of Mr. Peter Kimani Chege titled “Evaluation of trypanocidal activity in selected medicinal plants in Kenya using trypanosoma evansi as a model”. Degree to be awarded in 2008: Department of Biochemistry and Biotechnology, Kenyatta University, Kenya

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9. REVIEWS TO INTERNATIONAL JOURNALS

Serving as a reviewer to European Journal of Obstetrics and Gynecology and Reproductive Biology (2004-to date)

Served as co-opted (adhoc) Reviewer to Journal of Bioscience ( 2002)

10. SERVICE TO UNIVERSITY OF NAIROBI COMMITTEES

a) Department of Biochemistry

June 2008 to date: serving as Chairman, Departmental complaints and general purpose committee Charged with

1. Handling complaints from students, staff and other stake holders at the department

2. Harmonization of training at the department 3. Overseeing income generating projects at the department 4. Evaluation of projects at the department 5. Internal moderation of examinations at the department 6. Improving and updating departmental strategic plan 7. Continuous monitoring and evaluation of departmental processes to maintain

ISO 9001/2008 Standards 8. Other matters as requested by Chairman of department

Chairman, Strategic Planning Committee, Department of Biochemistry (2005 to date)

Department’s representative to College of Biological and Physical Sciences Strategic Planning Committee (2005 to date)

Department’s chairman and representative to Nairobi International Trade fair (1997-2003)

Departmental representative to College of Biological and Physical Sciences, BPS environmental protection Committee (2000- to data)

b) Pre-clinical departments of The Faculties of Medicine and Veterinary Medicine at Chiromo Campus

Member; Ethical Evaluation Committee for Biomedical Research Proposals (2005- to date)

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c) College of Biological and Physical Sciences

Chairman, College Show Committee (CBPS) and Representative to the University of Nairobi Show Committee (2002 to 2006).

Served as a board member in numerous appointment Committees for academic and non teaching staff (2003 to date)

d) College of Health Sciences

Chairman, College Committee on Customer satisfaction (February 2010- to date)

Co-ordinator Faculty of Medicine and Representative to College of Health Sciences’ Organizing Committee at the Kenyan Universities Exhibition at KICC (2004)

College Representative to the Steering Committee of the University of Nairobi’s Science and Technology Park (2005 to date)

College delegate to University Academic Staff Union, UASU (2005 to 2007)

e) Special tasks undertaken for University of Nairobi

June 2005: Helped to develop 5 year Strategic plans for the department of Biochemistry and College of Biological and Physical Sciences at Garden Hotel Machakos. “Co-authored Strategic themes and objectives” for the C.B.P.S document

July 2005: Helped to develop the 5 year Strategic plan for Office of Dean, Faculty of Science and refined the 5 year strategic plan for the College of Biological and Physical Sciences of the University of Nairobi at Kaskazi Beach Hotel Mombasa “Co-authored Strategic themes and objectives”

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11. CURRENT RESEARCH INTERESTS

Immunological Role of Placenta and Blocking Factors in Post Implantation Pregnancy focusing on the role of symmetric and asymmetric placental IgG

Natural killer (NK) cells as markers of HIV-infection and Immunbiology during progression to AIDS and prognosis during ant-retroviral therapy.

Mushroom polysaccharide extracts in management of laboratory induced carcinogenesis.

Role of TGF-beta in endometriosis

12. SUPERVISON OF HONOURS AND GRADUATE STUDENTS AT UNIVERSITY OF NAIROBI AND ELSEWHERE

a) Honours students

2005: Supervised Honours project of Albert Nyangwansa titled “Detection of Symmetric and asymmetric IgG composition in non pregnant sheep” at the Department of Biochemistry, University of Nairobi

2005: Supervise Honours project for Maureen Juma titled “ Effects of basidiomyecetes extracts on enzyme marker levels during hepatocellular carcinoma induction and progression in mice” Department of Biochemistry, University of Nairobi

2006: Supervised Honours project of Dorine Nkatha Raiboni titled “Symmetric/Asymmetric IgG composition in serum and retro-placental blood of oviparous women” Department of Biochemistry, University of Nairobi

2006: Supervised Honour project of Samwel Kinuthia Gaithe titled “Effect of selected edible basidiomycete fruit body extracts on induced liver tumours in mice” Department of Biochemistry, University of Nairobi

2006: Supervised Honour project of Angela Njeri titled” Effect of Aloe vera on propagation of trypanosomes in trypanosome infected mice” Department of Biochemistry, University of Nairobi

2009: Supervised Honour project of Munywoki Sammy Mutisya titled” Effect of Chromium and Cinnamon supplementation on glucose and lipid levels in non-insulin dependent type 2 diabetes” Department of Biochemistry, University of Nairobi

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2009: Supervised Honour project of Ashmi Kirit Dodia” Recurrent pregnancy loss associated with anti-phospholipid syndrome and systemic lupus erythematosus” Department of Biochemistry, University of Nairobi

b) M.Sc. Students

Served as Principal University supervisor for the M.Sc. project of Mr. John Munderu Muchiri titled “Elution and Partial Characterisation of Immunoglobulins bound to Goat Placenta”. Degree awarded in November 2000: Department of Biochemistry, University of Nairobi, Kenya

Served as Principal University Supervisor for M.Sc. research project of Mr. Fred Onyango Onono. Project titled “T-cell responses in cattle immunized with a prototype anti-sporozoite sub-unit vaccine against Theileria parva.” Degree awarded in May 2004: Department of Biochemistry, University of Nairobi, Kenya

Served as Principal University supervisor for Mr. George Otieno Mala’s M.Sc. research project titled “Quantitation and partial characterization of placental bound immunoglobulin-G (IGg) in normal and pathological human placentae. Letter of award granted in 2005: (To graduate later): Department of Biochemistry, University of Nairobi.

Served as Principal University Supervisor for M.Sc research project of Carolyne Wasonga titled “Effect of edible Basidiomycetes fruit body extracts on induced liver tumor in mice”. Degree awarded in November 2006: Dapartment of Biochemistry, University of Nairobi, Kenya

Served as Principal University Supervisor for M.Sc. research project of Mr. Ezekiel Mecha titled “Natural Killer Cells and selected enzyme/metabolite profiles as markers of HIV infection and progression to AIDS. Degree awarded in November 2007: Department of Biochemistry, University of Nairobi, Kenya

Served as Principal University Supervisor for M.Sc. research project of Mr. Lemmy Wachira titled “Antigen/antibody interactions on goat placenta: Department of Biochemistry, University of Nairobi, Kenya (On leave)

c) Ph.D. students at The University of Nairobi, Kenya and elsewhere

Co-supervised Ph.D. project of Dr. Hilda Ohara titled “Induction of enhanced anti-sperm mucosal immune responses in the female genital tract of baboons; Papio Anubis (suspended).

Supervised development and launching of Ph.D project for Mr. Washington Ochieng titled “ Impact, surveillance and characterization of molecular diversity of HIV-1 subtypes and inter-subtype recombinations in Kenya in the year

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2002/2003. Mr. Ochieng subsequently moved on scholarship and has since successfully completed his Ph.D in The Federal Republic of Germany

Currently supervising Ph.D project of Ezekiel Mecha titled “Characterization of the TGF-beta signalosome and TGF-beta dependent endometrial cell proliferation; Justus Liebig University of Giessen, Giessen, Germany

Currently supervising Ph.D project of Leslie Sui titled “ Role of TGF beta in endometriosis. Department of Obstetrics and Gynecology, Justus Liebig University of Giessen, Germany

Currently supervising Ph.D project of Kennedy Muinamia titled “ Schistosoma mansoni tegument associated proteins as possible vaccine candidates against Schistosoma mansoni infection in humans. Department of Biochemistry, University of Nairobi, Kenya

Currently supervising development of Ph.D project proposal development for Ms. Faith Onditi titled “ Congenital infection in baboon foetus born to mothers with malaria

Additional Intellectual support for Ph.D students outside Kenya

I had a productive working collaboration with Dr. Susanne S Gruessner in 2003 through 2005 and together, we generated a number of publications some of which contributed towards achievement of the impact factors required for her Ph.D. Dr. Gruessner graduated with a Ph.D in February 2006 at Justus-Liebig Univeresity of Giessen in The Federal Republic of Germany

I provided intellectual support to Antje Zimmermann, a Ph.D student at Justus-Liebig University of Giessen, Germany on role of “Thrombophilic disorders in miscarriage”

I provided intellectual support to Y Shen, a Ph.D student in Germany who was in the year 2003 developing favourable culture conditions for eggs recovered from human ovaries following hCG stimulation at Justus Liebig University in Germany. I, in this respect, suggested that she includes a section in her Ph.D project to identify the kind of proteins secreted by maturing ova in culture as a way of selecting high quality ova for in vitro fertilization and good embryos for post-fertilization transfer into recipient women

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13. PUBLICATIONS

Total publications: 54 + 3 submitted papers

Publication summary 2 theses

25 abstracts

2 full papers published as Conference proceedings

25 papers in Refereed Journals

3 papers submitted to refereed journals

a) Theses

Omwandho CA (1989): Effects of Albendazole therapy on serum proteins and Leukocyte Counts of Hydatid patients. M.Sc. Thesis (Degree awarded in 1992).

Omwandho CA (1996): Ovine placental Immunoglobulins: purification, partial Characterization and some in vitro Biological Activities. Ph.D Thesis ( Degree awarded in February 1998).

b) Abstracts 1. Omwandho C. A., Falconer, J., Roberts TK (1994): Purification and

characterization of immunoglobulins bound to placenta of sheep. Proceedings of the first international conference of World placental Associations, Sydney, Australia: In Placenta 1994: A53 pp 15.

2. Omwandho C. A., Peters, C., Falconer, J., Roberts TK (1994): Sheep placental

IgG inhibits human Natural killer cell cytotoxicity: In Proceedings of the First International Conference of World Placental Associations, Sydney, Australia: Placenta 1994: A54 pp 15.

3. Roberts, TK., Omwandho, CA., Peters, C., Falconer, J (1995): Inhibition of human

Natural Killer cell cytoxicity by sheep placental IgG: In proceedings of the sixth International Congress of Immunology, July 1995 Washington DC. American Journal of Reproductive Immunology 1995 Abstract P327.

4. Omwandho, CA., Falconer, J., Roberts TK (1996): Re-association of human and

ovine placental eluate immunoglobulins with acidified trophoblast vesicles: In proceedings of the 13th Rochester Trophoblast association and Thomas Wegmann Memorial Symposium on Reproductive Immunology, Banff, Canada. Abstract C17 American Journal of Reproductive Immunology.

5. Omwandho, CA., Peters, C., Falconer, J., Roberts, T.K., and Tumbo-Oeri, A. G.

(2001): Is placental IgG toxic to natural killer cells? In proceedings of the International Union of Biochemistry and Molecular Biology/South African Societies

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for Biochemistry and Molecular Biology Special meeting on the Biochemical and Molecular Basis of Disease Cape Town, South Africa (19th to 23rd November 2001. Abstract No. P155.

6. Susanne E. M. Gruessner, Volker Klingmueller, Charles O. A. Omwandho, Rainer

M. Bohle, Hans Rudolf Tinneberg (2004). Detection of Vascular responses to Hypoxia in the pre-term ovine fetus: a preliminary study using 3 – D Doppler spectroscopy. In Proceedings of the 51 st Annual Scientific Meeting of The Society for Gynecologic Investigation, March 24-27, 2004 ,Houston, Texas, USA. Journal of Society for Gynecological Investigations 11: (Suppl No2.): A 504, pp243.

7. Gruessner S, Omwandho C, Klingnueller V, Tinneberg HR (2004) Partielle unde

komplette Reduktion de uterinen Perfusion beim Schaffeten – 2D- vs 3D- Doppler – Spektralanalysen. Archives of Gynecology and Obstetrics, Sept 2004, Vol 270 (Suppl 1): S10.

8. Gruessner S, Omwandho C. A. O., V. Klingmueller, Bohle R., Tinneberg H.R.

(2004) 2D – vs 3D – Spektralanalyse vaskulärer Gefäßreaktionen bei fetaler Hypoxämie im Tier experiment. Ultrasound in Medicine 2004 Okt; Vol 25 (Suppl 1).

9. S. Gressner, C. A. Omwandho, V. Klingmueller, R. M. Bohle (2004): Effect of

intermittent uterine occlusion on hemodynamic changes in pre-term and near term ovine twin fetuses. In: Special Issue of 14th World Congress on Ultrasound in Obstetrics and Gynecology (Stockholm, Sweden 31st August to 4th September 2004 Ultrasound in Obstetrics and Gynecology 24: 341

10. S. Gruessner, C. A. Omwandho, V. Klingmueller, R. M., Bohle, H.-R Tinneberg (2005). Cerebro and cardiovascular responses and oxygen consumption during prolonged hypoxia in fetal sheep. In Proceedings of the 15th World Congress on Ultrasound in Obstetrics and Gynecology (ISUOG 2005), 25th –29th September 2005, Vancouver, Canada. Ultrasound in Obstetrics and Gynecology 26: 449

11. Gruessner S, Omwandho C, Klingmueller V, Tinneberg HR. Partielle und komplette Reduktion der uterinen Perfusion beim Schaffeten – 2D- vs. 3D-Doppler- Spektralanalysen. 55. Kongreß der DGGG- Deutsche Gesellschaft für Gynäkologie und Geburtshilfe, 14.-17. Sept. 2004, Hamburg, Germany. (In Proceedings of the 55th Congress of German Society for Gynecology and Obstetrics)

12. Gruessner S, Omwandho C.A.O., Klingmueller V, Bohle R., Tinneberg H.R. 2D- vs 3D- Spektralanalyse vaskulärer Gefäßrektionen bei fetaler Hypoxämie im Tierexperiment. 28. Dreiländertreffen DEGUM, SGUM, ÖGUM, 6.-9. Oktober 2004, Hannover, Germany. (In Proceedings of the 28th meeting of combined Swiss, German and Austrian Societies for Gynecology and Obstetrics)

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13. Daudi K Langat, Pedro J Morales, Charles O. Omwandho, Asgerally T Fazleabas, Joan S. Hunt. Polymorphisms in Paan-AG promoter influences NF-kB binding and transcriptional activity in HEK293 cells. (In proceedings of the 39th Meeting of the society for the study of Reproduction. July 2006, Omaha, Nebraska, U.S.A. Abstract No. 13, Biology of Reproduction, Special Issue, August 2006, pp 73-4

14. E. Mecha, J. Mukuria, G.Foglia and C. Omwandho (2006). Natural killer cells,

CD4+/CD8+ cell ratios and selected liver and kidney function enzyme and metabolite levels in HIV infection and progression to AIDS. Abstract Number CDA0053, XVI International AIDS Conference, Sydney, Australia

15. Daudi K Langat, Pedro J Morales, Charles O Omwandho, Asgerally T Fazleabas

and Joan S Hunt. Polymorphisms in Paan-AG promoter influences NF-kB binding and transcriptional activity in HEK293 cells. (In proceedings of the 94th American Association of Immunology Annual Meeting: May18-22, Miami Beach, Florida). The Journal of Immunology 2007, 178:42.12

16. Takayuki Kubota, Makiko Yokayama, Masato Kishima, Satoko Watanabe, Masato

Ohota, Hirokazu Hikono, Charles O.A. Omwandho and Shigeki Inumaru. Gene expression of chicken interleukine-4 by baculovirus. In Special Issue 8th International Veterinary Immunology Symposium. Ouro Preto-Brazil, August 15th-19th 2007):. Veterinary Immuinology and Immunopathology Vol 128: Issues 1-3, pp309

17. Gruessner S, Bohle RM, Heckmann M, Omwandho CA, Alzen G. Fetal

malformations: comparison of MR imaging and ultrasonography for diagnosis. Ultrasound in Obstetrics and Gynecology 2007 Sept 21;30(4): 464

18. Gruessner S, Bohle RM, Heckmann M, Omwandho CAO, Alzen G. Prenatal and

postnatal management of congenital cystic adenomatoid lung malformation diagnosed by ultrasound and MR imaging:two case reports. Ultrasound in Obstetrics and Gynecology 2007 Sept 21; 30 (4): 565

19. Carolyne GO Wasonga, Sheila A Okoth, Joseph C Mukuria and Charles OA

Omwandho. Mushroom polysaccharide extracts delay progression of carcinogenesis in mice. (In proceedings of 17th International Mushroom Congress: 20-24May 2008, Cape Town, South Africa)

20. Charles O.A. Omwandho, Susanne E. Gruessner, John Falconer, Timothy K

Roberts, Hans Rudolf Tinneberg (2008). Is intravenous immunoglobulin, IVIG a multi-head magic bullet? In proceedings of 5th African Association of Phyisiological Sciences Congress, 27th July – 1st August 2008, Nairobi, Kenya)

21. Charles O.A. Omwandho, Susanne E. Gruessner, John Falconer, Hans Rudolf

Tinneberg, Timothy K Roberts (2008). (2008). Is ovine placental IgG toxic to human peripheral blood natural killer cells? In proceedings of 5th African Association of Phyisiological Sciences Congress, 27th July – 1st August 2008, Nairobi, Kenya)

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22. Carolyn G. Wasonga , Sheila A. Okoth , Joseph C. Mukuria and Charles

O.A.Omwandho (2008). Mushroom polysaccharide extracts delay progression of carcinogenesis in mice (In proceedings of 5th African Association of Phyisiological Sciences Congress, 27th July – 1st August 2008, Nairobi, Kenya)

23. Mecha E, Ayienda C, Mukuria J, Foglia G, Omwandho C (2008). Human natural

killer cell activity is positively associated with CD4+ T cell counts in asymptomatic HIV-1 patients (In proceedings of 5th African Association of Phyisiological Sciences Congress, 27th July – 1st August 2008, Nairobi, Kenya)

24. Mecha E, Omwandho C, Mukuria J, Ayienda C, Mongina C. Natural killer cell

number and function is well preserved in asymptomatic human immuno-deficiency virus type 1 (HIV-1) but its activity and number decreases when CD4+ T-cell counts fall. (Presented in Mexico in August 2008

25. Konrad L. Omwandho C.A, von Hobe A. –K, Sui C, Kloeppels K, Hersemeyer K,

Tinneberg H. –R (2010). Are cell lines a suitable model for studying endometriosis?. (In proceedings of 14th World Congress of Gynecological Endocrinology, ISGE, March 4 - 7,2010, Firenza Italy)

c) Full papers published as conference proceedings

1. Omwandho, CA., Okello, G. B. A. and Tumbo-Oeri, AG (1990): Effects of lbendazole therapy on leukocyte counts in hydatid patients; In: Proceedings of the 11th KEMRI/KETRI Scientific. Conference. Nairobi (Kofi-Tsekpo)Ed. Pp. 171 – 179.

2. J. M. Muchiri, C.A. Omwandho, A.G.Tumbo – Oeri, E. O. Wango, T. K. Roberts

2000). Elution of Goat Placental Immunoglobulins. In proceedings of the Sixth Biochemical Society of Kenya Annual Scientific Conference. pp. 12 –14.

d) Publications In Refereed Journals 1. Oloowokere, JO., Konji, VN., Makawiti, DW., Kiaira, JK., Kamau, JMZ and

Omwandho, CA (1991): Defects in resting metabolic rates and mitochondrial respiration in Kwashiokor and Dietary obese rats. Journal of Camparative Physiology B 161: 319 – 322.

2. Oloowokere, JO., Makawiti, DW., Konji. VN., Omwandho, CA (1991):

Experimental Kwashiokor and Obesity: Differences in Energy Metabolism and relative Organ body weight Ratios. International Journal of Biochemie Physics 1: 26 – 28.

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3. Oloowokere, JO., Konji, VN., Omwandho, CA., Makawiti, DW (1991): Changes in Mitochondrial Oxidative phosphorylation characteristics in Dietary obese rats. Biokemistri 1: 65 – 70.

4. Konji, VN., Makawiti, DW., Kiaira, JK., Omwandho, CA., Oloowokere, JO (1993):

Defects in respiration in mitochondria isolated from liver of goats infected with Trypanosoma Congolense. International Journal of Biochemie Physics 2: 152 – 154.

5. Omwandho, CA., Hall, AL., Falconer, J., Roberts, TK., (1997) Elution and partial

characterization of immunoglobulins bound to ovine placenta. Immunology and Cell Biology 75: 231 – 237.

6. Omwandho, CA, Tinneberg HR, Tumbo-Oeri, AG., Roberts TK., Falconer J

(2000). Recurrent Pregnancy losses and the role of Immunotherapy. Archives of Gynecology and Obstetrics 264; 3-12

7. John M.Muchiri, Charles O. A. Omwandho, Aloys G. Tumbo-Oeri, Emmanuel O.

Wango, Timothy K. Roberts, and Hans R. Tinneberg (2000). Purification and partial characterization of goat placental IgG: a possible model for the study of human maternal foetal interaction: African Journal of Health Sciences 7: 136 – 139.

8. Omwandho, CA., Tinneberg H.R., Tumbo Oeri AG., Roberts TK., Falconer J

(2001): Immunological role of placenta, Blocking factors and NK Cells in the post implantation pregnancy. African Journal of Health Sciences 8: 2 – 16.

9. Omwandho, CA., Peters C., Falconer, J., Roberts TK (2001): Ovine and Human

placental IgG inhibit human natural killer cell cytotoxicity in vitro. African Journal of Health Sciences 8: 47 – 54.

10. Tumbo-Oeri AG, Omwandho CA, Muchiri JM (2001). Possible Immunological

basis for recurrent spontaneous abortions: a review. East African Medical Journal 78(11): 586-589

11. Tumbo – Oeri AG., Omwandho CA (2002): Cellular and molecular interactions in HIV infections: A review. East African Medical Journal 79(5) : 249 – 253.

12. Charles O. A. Omwandho, Susanne E. M. Gruessner, Timothy K. Roberts,

Hans R Tinneberg (2004). Intravenous Immunoglobulin (IVIG): Modes of action in the clinical management of Recurrent Pregnacy loss and selected Autoimmune disorders. Clinical Chemistry and Laboratory Medicine 42 (4): 359 – 370.

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13. Jaeger M, Grussner SE, Omwandho CO, Klein K, Tinneberg HR, Klingmuller V (2004) Cranial Sonography for Newborn Screening: A 10 year retrospective Study in 11, 887 Newborns. Fortschr Rontg;Rofo (Research in Radiology) 176 (6): 852 – 858.

14. Susanne E. M. Gruessner, Charles O. A. Omwandho, Thomas Dreyer, Renate

Blutters-Sawatzki, Alfred Reiter, Hans R. Tinnerberg, Rainer M. Bohle (2004): Management of stage I cervical sarcoma botryoides in childhood and adolescence. European Journal of Pediatrics 163: 452 – 456

15. C. A. Omwandho, J. Falconer, S. E. Gruessner, E. Mecha, A.G. Tumbo-Oeri, H-

R Tinneberg and T. K. Roberts (2005). Human placental immunoglobulins show unique re-association patterns with isologous and third party acid treated trophoblast microvesicles in vitro. East African Medical Journal 82(6): 290 – 293.

16. C. A. Omwandho., S. E. Gruessner, J. Falconer, E. Mecha, A. G. Tumbo –Oeri, H,

R. Tinneberg and T. K. Roberts (2005). Immunoglobulin G (lgG) bound to ovine placenta is eluted by surgical cannulation and acid perfusion in situ. East African Medical Journal 82 (9): 468 – 472

17. Charles O. A. Omwandho, Susanne E. M. Gruessner, Hans R Tinnerberg

(2006). Early Pregnancy loss and neonatal deaths associated with Klebsiella pneumonia infection: A mini Review of possible Occupational Health Risk. Archives of Gynecology and Obstetrics 273 (5): 258 – 260

18. Omwandho C A. Gruessner E. E. Falconer J, Tumbo-Oeri AG, Mala G, Mecha

E, Tinneberg H. R., Roberts TK (2006) Ovine Placental eluate Immunoglobulins recognize isologous and third party acid treated trophpblast microvesicle antigens in Vitro . Journal of the South African Veterinary Association 77 (1): 24 – 27

19. Daudi K. Langat, Pedro J. Morales, Charles O.Omwandho, Asgerally T.

Fazleabas (2007). Polymorphisms in the Paan-AG promoter influence NF-kappa B binding and transcriptional activity. Immunogenetics 59(5) 359-366

20. Suwandinata F, Tinneberg HR, Omwandho COA, Bohle R. M, Gruessner S. E.

(2007) Management of vulvar melanoma and review of literature. European Journal of Gynecological Oncology 3: 220-224

21. Ferdhy Suryadi Suwandinata, Susanne E.M. Gruessner, Charles O.A.

Omwandho, Hans Rudolf Tinneberg. Pregnancy preserving myomectomy: preliminary report on a new surgical technique. European Journal of Contraception and Reproductive Health Care 2008;1- 4

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22. Carolyne GO Wasonga, Sheila A Okoth, Joseph C Mukuria and Charles OA Omwandho (2008). Mushroom polysaccharide extracts delay progression of carcinogenesis in mice. Journal of Experimental Therapeutics and Oncology 7:147-152

23. Frank Oehmke, Julia Weyand, Andreas Hackethat, Lutz Konrad, Charles

Omwandho, Hans-Rudolf Tinneberg (2009). Impact of endometriosis on quality of life: A pilot study. Gynecological Endocrinology 25(11): 722-725

24. Charles Omwandho, Lutz Konrad, Gulden Halis, Frank Oehmke, Hans-Rudolf

Tinneberg (2010). Role of TGF-beta in normal human endometrium and endometriosis Human Reproduction 25 (1): 101-109

25. Charles O.A. Omwandho, Takayuki Kubota (2010). Salmonella enteritidis: A mini

review of contamination routes and limitations to effective control. Japanese Agricultural Quarterly Journal 44 (1) 7-16

e) Papers submitted to refereed Journals

1. E. O. Mecha, C. A. Omwandho, A. G. Tumbo-Oeri, T. K. Roberts, Heat shock

proteins in disease and health (Submitted to East African Medical Journal)

2. Antje Zimmerman, Susanne E. M. Gruessner, Charles O.A. Omwandho, Bettina

Kemkes-Matthes. Thrombophilic disorders and miscarriage. (Submitted to European Journal of Obstetrics and Gynecology and Reproductive Biology)

3. Susanne E. Gruessner, Charles O.A. Omwandho, Philipp Soergel, Peter Hillemanns, Matthias Heckmann (Submitted to Maternal-Fetal and Neonatal Medicine)

f) Papers in preparation 1. Halis Guelden, Omwandho Charles, Hopp Karsten, Ebert Andreas. Expression

of EGF-receptors in chorionic villi of women with hypertension in pregnancy 2. Susanne E.M.Gruessner, Charles O. A. Omwandho, and Hans – R Tinneberg.

Doppler velocimetry and Fetal heart rate in pregnancies complicated with pre-eclampsia and Hellp syndrome

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3. Susanne E. M. Gruessner, Charles O. A. Omwandho, Rosengarten B, Hans – R Tinneberg, Klingmuller V. Measurement of flow velocity in fetal lambs by 3D- Spectroscopy.

14. SELECTED WORKSHSOPS ATTENDED / FACILITATED

a) Workshops Attended Nov 1988: Two week (NORAD KEN 046) sponsored practical course on

practical applications of DNA techniques in microbiology at Kabete Campus of the University of Nairobi

Sept. 1990: International Cell Research Organization (ICRO)/ UNESCO

one month training workshop on Biological membranes and Liposomes at Shangai Institute of Biochemistry and Molecular Biology, Shangai, China

May 13th-19th 2001: An intensive course in Structural Biology and Bioinformatics (Buea University Cameroon): Certificate Awarded. Aug. 1st - 17th 2001: Advanced Course in Structural Biology and Bioinformatics (Lunds University, Sweden): Certificate Awarded. Nov. 12th - 16th 2001: Proteomics workshop (University of Cape Town, South Africa). Nov. 17th - 19th 2001: Biochemical Education Workshop (University of Cape Town, South Africa).

b) Workshops Facilitated

August 1st –6th 2004: A ‘Facilitator’ in a Proteomics and Molecular Biochemistry Workshop at the departments of Botany/ Biochemistry University of Nairobi, and department of Molecular Biology and Biochemistry, University of Herdfordshire, United Kingdom.

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28th Feb – 11-3-2005; A facilitator in a Protein/Molecular Biology workshop at the departments of Botany/ Biochemistry University of Nairobi, and department of Molecular Biology and Biochemistry, University of Herdfordshire, United Kingdom.

19th-30th August 2009: A facilitator in a Laboratory Techniques course for

Laboratory Technologists and Lecturers of Technology

Institutes at the Department of Biochemistry University of Nairobi, Kenya

15. INVITATIONS AS A VISITING SCIENTIST / PROFESSOR OR CONSULTANT

a) Visiting Scientist / Professor 1. 2000: Invited guest scientist (one day) during an Annual Scientific Review of the

Scientific findings at the Institute of Primate Research Karen, for the period 1999-2000. The review was centred on the Institute’s findings in the areas of Virology, Reproductive Biology,Infectious diseases. Conservation and Primate Medicine.

2. May-July 1999: Invited as a guest scientist to undertake short-term research in

reproductive Biochemistry and Immunology at Bielefeld Institute of Reproductive Medicine, Bielefeld, Germany. Host: Prof. Hans. –R Tinneberg

3. 1st May - 31st July 2003: Invited as a guest scientist to undertake short-term

research in reproductive Biochemistry and Immunology at Justus Liebig University, Giessen, Germany. Host: Prof. Hans. –R Tinneberg: Director, University Women’s Hospital, Justus Liebig University, Giessen, Germany.

4. August 2004. Invited Guest Scientist to the department of Anatomy and Cell

Biology, Kansas University Medical School, Kansas, U.S.A. The aim of this invitation was to facilitate development of common research initiatives in reproductive immunology and biochemistry centred on concepts relating to HLA-G expression on the human placenta and associated reproductive implications. Host: Prof. Joan S. Hunt, a University Distinguished Professor, and Assistant Dean, School of Reproductive Medicine, Kansas University Medical School, Kansas, U.S.A.

5. 1st October 2005 - 31st March 2006: A six month offer of Sabbatical as a visiting

Professor to department of Anatomy and Cell Biology, Kansas University Medical School, Kansas U.S.A. Host: Prof. Joan S. Hunt, a University Distinguished Professor and Vice Chancellor for Research, Kansas University Medical School, Kansas, U.S.A.

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6. January 2006: Invitation Fellowship by Japanese Society for Promotion of Science JSPS, (a highly competitive fellowship available globally to Senior or Mid Term Scientists with excellent research records). The ten-month award (1st December 2006 to 31st September 2007) was tenable at department of drug formulation development, National Institute of Animal Health, Tsukuba, Japan. The aim was to use gene manipulation technology to produce avian cytokines to be used as adjuvants in production of IgA for use in liposome coated oral vaccines to salmonella infections in chicken

7. July 2008: Awarded special grant by Alexander von Humboldt Senior fellowship for a

six month research stay at Justus Liebig University of Giessen Germany. Host: Prof. Hans. –R Tinneberg: Director, University Women’s Hospital, Justus Liebig University, Giessen, and Philips University of Marburg, Germany

b) Invitations as a Consultant

January 2004: Invited by the Director for Research Programmes on Sustainable Use of Dryland Biodiversity (RPSUD) to serve as a Consultant in selection of applications to be funded (up to US $ 20,000) by the Swedish International Agency for Development (SIDA) and Swedish Agency for Research Cooperation with Developing countries (SAREC).

16. ONGOING SCIENTIFIC RESPONSIBILITIES

1. Reviewer: European Journal of Obstetrics & Gynaecology and Reproductive Biology in the areas of pregnancy loss and abortions, recurrent pregnancy loss, placental physiology and pathology, and pre-eclampsia (2004- to date).

17. CONTRIBUTIONS TO SCIENTIFIC LEADERSHIP

a). One of my articles “Omwandho, CA, Tinneberg HR, Tumbo-Oeri, AG., Roberts

TK., Falconer J (2000). Recurrent Pregnancy losses and the role of Immunotherapy. Archives of Gynaecology and Obstetrics 264; 3-12” Was listed number THREE of THE ONLY SIX SCIENTIFIC PUBLICATIONS FROM AROUND THE WORLD (year 2004) that were reviewed to develop an insurance Policy document based on use of intravenous immunoglobulin for experimental immunotherapy in the management of reproductive failure by CareFirst/BlueCross/ Blue Shield Insurance Companies in United States of America. This paper is still listed as a resource at this site (June 2010)

b). Five of my papers listed below have been listed as resource materials at the

“British Library Direct” web site (2004 to date)

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C. A. Omwandho., S. E. Gruessner, J. Falconer, E. Mecha, A. G. Tumbo –Oeri, H, R. Tinneberg and T. K. Roberts (2005). Immunoglobulin G (lgG) bound to ovine placenta is eluted by surgical cannulation and acid perfusion in situ. East African Medical Journal 82 (9): 468 – 472

Charles OA., Omwandho, Susanne E.M. Grussner, Timothy K. Roberts, Hans Tinneberg (2004). Intravenous Immunoglobulin (IVIG): Modes of action in the clinical management of Recurrent Pregnancy loss and selected Autoimmune disorders Clinical Chemistry and Laboratory Medicine 42 (4): 359-370

Tumbo-Oeri AG, Omwandho CA (2002) Cellular and molecular interactions in HIV infections: a review. East African Medical Journal 79: 249-253 (ISSN 0012-835X)

Omwandho, CA, Tinneberg HR., Tumbo-Oeri Ag., Roberts TK., Falconer J (2001): Immunological role of plancenta, Blocking factors and NK cells in the post implantation pregnancy. African Journal of Health Sciences 8: 2-16. (ISSN 1022-9272)”

Tumbo-Oeri AG, Omwandho CA, Muchiri JM (2001) Possible immunological basis for recurrent spontaneous abortions: a review East African Medical Journal 78 (11)586-589 (ISSN 0012-835X)

c). One of my papers “Charles OA., Omwandho, Susanne E.M. Grussner, Timothy

K. Roberts, Hans Tinneberg (2004). Intravenous Immunoglobulin (IVIG): Modes of action in the clinical management of Recurrent Pregnancy loss and selected Autoimmune disorders Clinical Chemistry and Laboratory Medicine 42 (4): 359-370

Was in the year 2004 listed in position 1 of 10 articles at the “Cytotect Biotest“ ”Disease and Treatment Map” website. The same article was later listed number 2 of 100 at the same website in the year 2005/6

d) One of my papers below:

Susanne E. M. Gruessner, Charles O. A. Omwandho, Thoma Dreyer, Renate Blutters-Sawatzki, Alfred Reiter, Hans R. Tinnerberg, Rainer M. Bohle (2004): Management of stage I cervical sarcoma botryoides in childhood and adolescence. European Journal of pediatrics 163: 452 – 456

Is among “selected publications” (number 13 of 29) articles catalogued by Borstel in the “Central Directory of National Reference for Clinical and Experimental pathology” in the years 2006 &2007

e) My papers are currently listed in a number of global databanks including

BioInfoBank Library on “latest papers on antigens Immunology” (CA Omwandho,

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J Falconer, SE Gruessner, E Mecha, AG Tumbo-Oeri, TK Roberts, HR Tinneberg: Human placental Immunoglobulins show unique re-association patterns with isologous and third party acid treated trophoblast microvesicles in vitro. East African Medical Journal 82(6): 290-193

f) My papers are widely cited by other researchers around the world

18. MEMBERSHIP TO PROFESSIONAL ASSOCIATIONS

1. Member, Kenya Society for Immunology 2. Member, Biochemical Society of Kenya 3. Member, Africa Biotechnology Stake holder’s Forum (ABSF) 4. Member, Bionet Africa 5. Member, Federation of African Societies for Biochemistry and Molecular Biology 6. Member, Kenya Physiological Society

19. GRANTS, MATERIAL AND CASH DONATIONS RECEIVED

1996-2002: 11,000 Australian $ (US$ 8,000) worth in material and fine laboratory reagents. Prof. Tim Roberts, Senior Assistant Dean, School of Mathematics and Science, University of Newcastle, New South Wales, Australia

2002: DM 12,000-(US$8,000): Prof. Hans –R Tinneberg, Bielefeld Institute

of Reproductive Medicine, Bielefeld, Germany

2003: 2,200 Euros (US$4,800) worth of reagents from Prof. Hans – R Tinneberg, Director, University Women’s Hospital and President, Justus Liebig University of Giessen Germany and European College of Obstetrics and Gynecology.

2004: The late Professor Peter Campbell (Signatory to FASBMB account); US$ 560 in laboratory reagents.

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2004: US$ 3,250 (travel & Accommodation) grant – Prof. Joan Hunt Distinguished Professor and Assistant Dean, School of Reproductive Medicine, University of Kansas, Kansas, United States of America (appropriation in aid).

2004: US US$ 2,283 in laboratory reagents from Harding Montgomery, Berkshire, England

2005: US$12,000 and round trip air ticket to and from Kansas to participate in collaborative research for six months at the University

of Kansas Medical School, USA between 1st October 2005 to 31st March 2006:Donated by Professor Joan Hunt, The Vice-Chancellor for research at Kansas University Medical School, Kansas, United States of America (appropriation in aid)

2006: Approx.. 3,800,000 Japanese Yen Award (plus round trip air ticket) from Japanese society for promotion of Science to support a ten month stay at the National Insitute for Animal Health in Tsukuba Japan(appropriation in aid)

2009: 20, 000.00 Euros (approx. K.shs 2, 080,000.00 ) Equipment Grant from Alexander von Humboldt Foundation of Germany

2009: 1,058.00 Euros ( approx imately Ksh 110,000.00) Book donation from Alexander von Humboldt foundation of Germany

20. ADDITIONAL EQUIPMENT SOURCED FOR UNIVERSITY OF NAIROBI

2009: The following laboratory equipment were donated by Prof. Hans Rudolf Tinneberg, Director, University Women’s Hospitals, Justus Liebig University of Giessen and Philips University of Marburg, Germany

Mobile Laminar Flow (designed for level III laboratory use)

Microplate reader and Printer

Orbital shaker

Heater/Stirrer

5 sets of micropittes and tips

Micropipette stand

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21. ACADEMIC AND PROFESSIONAL REFEREES 1. Prof. T. K. Roberts,

Biological Sciences Department University of Newcastle, NSW 2308, Australia

2. Prof. Hans-R Tinnerberg,

Director, University Women’s Hospital, Justus-Liebig University, Klinikstrasse 28, D-35392 Giessen, Germany

3. Prof. Richard Mibey,

Vice-chancellor, Moi University, P.O. Box 3900, Eldoret, Kenya.