登记号 CTR20140661 试验状态 主动暂停

申办者联系人 康越 首次公示信息日期 2014-12-26

申办者名称 AbbVie Inc./AbbVie Inc.AbbVie Ireland NL B.V./AbbVie Ireland NL B.V.艾

伯维医药贸易（上海）有限公司/

一、题目和背景信息

登记号 CTR20140661

适应症 糖尿病肾病

试验通俗题目 Atrasentan的糖尿病肾病研究

试验专业题目 评价 Atrasentan 对Ⅱ型糖尿病肾病受试者肾脏预后影响的

随机多国家多中心双盲平行安慰剂对照研究 SONAR：

Atrasentan的糖尿病肾病研究

试验方案编号 M11-352

受理号 企业选择不公示

药物名称 Atrasentan (ABT-627)

药物类型 化学药物

二、申办者信息

申办者名称 AbbVie Inc./AbbVie Inc.

AbbVie Ireland NL B.V./AbbVie Ireland NL B.V.

艾伯维医药贸易（上海）有限公司/

联系人姓名 康越

联系人电话 021-62631384 联系人 Email yue.kang@abbvie.com

联系人邮政地址 上海市南京西路

288号创兴金融中

心 17楼

联系人邮编 200003

经费来源 完全自筹

三、临床试验信息

1、试验目的

评价与安慰剂相比, Atrasentan对 2型糖尿病肾病受试者血清肌酐倍增所需时

间或终末期肾病（ESRD）出现时间的影响。此外，本研究评估与安慰剂相比,

Atrasentan对下述结果的影响：心血管发病率和死亡率、尿白蛋白排泄率、估

算的肾小球滤过率变化，还评估对Ⅱ型糖尿病肾病受试者生活质量的影响。

2、试验设计

试验分类 安全性和有效性

试验分期 III期

设计类型 平行分组

随机化 随机化

盲法 双盲

试验范围 国际多中心试验

3、受试者信息

年龄 18岁至

85岁

性别 男+女

健康受试者 无

入选标准 1.受试者身患Ⅱ型糖尿病，在筛选期之前 3个月内，至少接受一

种降糖药物和 ACEi/或 ARB（RAS抑制剂）治疗。受试者不能为Ⅰ

型糖尿病患者（定义为：在 35岁之前发病，并在 1型糖尿病确诊

后 12月内需要长期胰岛素治疗）。

2.HbA1c ≤ 12%

3.为了进入准备期，根据实验室筛选指标，受试者必须满足下述

标准：估算的 GFR 为 25~75mL/min/1.73m2，UACR≥300、<5000 mg/g

（eGFR在 60~75 mL/min/1.73m2 之间的受试者人数应占总人群的

10%以下；血清白蛋白≥3.0g/dL（30 g/L）；BNP≤200pg/mL（200

ng/L）；SBP≥100、≤160 mmHg；血钾>3.0（3 mmol/L）、≤5.5

mEq/L（5.5 mmol/L）；

4.为了进入强化期，根据准备期最后一次访视结果，受试者必须

满足下述标准：接受 RAS抑制剂 MTLDD剂量已治疗 4周，且未调

整过剂量；在筛选时，接受 RAS抑制剂 MTLDD 剂量治疗、但未接

受利尿剂治疗（除非有医疗禁忌症）的受试者必须进入至少两周

的准备期。

5.为了进入双盲治疗期，根据强化期最后一次访视结果，受试者

必须满足下述标准：在强化期内，已接受 RAS抑制剂 MTLDD剂量

治疗过 6周，且未曾调整过剂量；接受任一剂量利尿剂，除非经

研究者判断有医疗禁忌症或临床不能耐受（即：低血压或低钾血

症）；从强化期开始的 6周强化期间，体重变化<3kg，血清 BNP

绝对值<300pg/mL（300 ng/L）；在强化期结束时，受试者不得发

生 AKI事件（定义为：在强化期第 6周访视时即访视 E5，血清肌

酐相对基线变化升高 0.5 mg/dL以上，相对基线升高率大于 20%）。

排除标准 1.在筛选前 6个月内，有中度或重度外周水肿、与外伤无关的肺

水肿或面部水肿等病史的受试者，或有粘液性水肿病史的受试者；

2. 有肺动脉高血压病史且需要输氧治疗和/或内皮素受体拮抗剂

或磷酸二酯酶治疗的受试者；或有任一种肺病（比如：慢性阻塞

性肺病、肺气肿、肺纤维化）且需要输氧治疗的受试者；

3. 受试者已有记录诊断为心衰，或因心衰或与心衰相符的症状（运

动性呼吸困难、脚肿、端坐呼吸、发作性夜间呼吸困难；其他原

因未能解释这些症状）而住院，且治疗心衰的药物或其他治疗措

施有变化。

4. 已知受试者罹患非糖尿病肾病（肾结石除外）；

5. 在过去 6个月内，受试者有症状性低血压病史；

目标入组人数

国际多中心试验：总体 4148人中国 280人

实际入组人数

国际多中心试验:总体 3668人,中国 203人;

4、试验分组

试验药 序号 名称 用法

1. Atrasentan

(ABT-627)

薄膜衣片；规格 0.75mg；口服，一

日一次，48个月。

对照药 序号 名称 用法

1. 安慰剂 薄膜衣片；口服，一日一次，48个

月。

5、终点指标

主要终点指标

及评价时间

序

号

指标 评价时间 终点指标选择

1 首次出现肾脏复合终点所

需时间：血清肌酐倍增（30

天血清肌酐确认）或 ESRD

发病（需要长期透析或肾

移植或肾死亡）。

大约 48个月 有效性指标+

安全性指标

次要终点指标

及评价时间

序

号

指标 评价时间 终点指标选择

1 UACR从基线至随机分组

第 24个月访视时的变化；

从第 0天至第 24

个月

有效性指标+

安全性指标

2 从随机分组起治疗 3个月

后，eGFR下降 30%所需时

间；

大约 24个月 有效性指标+

安全性指标

3 出现心肾复合终点所需时

间：血清肌酐倍增、ESRD、

CV死亡、非致命性心肌梗

死、非致命性卒中；

大约 48个月 有效性指标+

安全性指标

4 出现 CV复合终点所需时

间：CV死亡、非致命性心

肌梗死和非致命性卒中；

大约 48个月 有效性指标+

安全性指标

6、数据安全监

察 委 员 会

（DMC）

有

7、为受试者购

买试验伤害保

险

有

四、第一例受试者入组日期

2015-02-02 国内

2013-06-12 国际

五、试验终止日期

2017-11-10 国内

2017-11-10 国际

六、研究者信息

1、主要研究者信息

姓

名

侯凡凡 职称 教授，主任医师，中国科学

院院士

电

话

020-61641591 Email ffhouguangzhou@163.com

邮

政

广东省广州市广州大道北 1838号 邮编 510515

地

址

单

位

名

称

南方医科大学南方医院

2、各参加机构信息

序

号

机构名称 主要研究者 国家 省（州） 城市

1 南方医科大学南

方医院

侯凡凡 中国 广东省 广州

2 广东省人民医院 史伟 中国 广东省 广州

3 复旦大学附属华

山医院

郝传明 中国 上海 上海

4 北京大学人民医

院

左力 中国 北京 北京

5 北京大学人民医

院

纪立农 中国 北京 北京

6 北京协和医院 李玉秀 中国 北京 北京

7 北京大学第一医

院

郭晓蕙 中国 北京 北京

8 北京大学第三医

院

王松 中国 北京 北京

9 上海交通大学医

学院附属仁济医

院

倪兆慧 中国 上海 上海

1

0

武汉大学人民医

院

丁国华 中国 湖北省 武汉

1

1

上海交通大学医

学院附属瑞金医

院

陈楠 中国 上海 上海

1

2

山东省立医院 赵家军 中国 山东省 济南

1

3

青岛大学附属医

院

徐岩 中国 山东省 青岛

1

4

第四军医大学第

一附属医院（西京

医院）

姬秋和 中国 陕西省 西安

1

5

第四军医大学第

一附属医院（西京

医院）

孙世仁 中国 陕西省 西安

1

6

中国人民解放军

第三军医大学第

一附属医院

吴雄飞 中国 重庆 重庆

1

7

南京医科大学第

一附属医院

邢昌赢 中国 江苏省 南京

1

8

西安交通大学第

一附属医院

施秉银 中国 陕西省 西安

1

9

佛山市第一人民

医院

肖观清 中国 广东省 佛山

2

0

华中科技大学同

济医学院附属同

济医院

徐钢 中国 湖北省 武汉

2

1

四川大学华西医

院

付平 中国 四川省 成都

2

2

东南大学附属中

大医院

刘必成 中国 江苏省 南京

2

3

复旦大学附属中

山医院

丁小强 中国 上海 上海

2

4

上海市第六人民

医院

贾伟平 中国 上海 上海

2

5

首都医科大学附

属北京同仁医院

杨金奎 中国 北京 北京

2

6

大连医科大学附

属第二医院

苏本利 中国 辽宁省 大连

2

7

中山大学附属第

三医院

翁建平 中国 广东省 广州

2

8

北京大学第一医

院

赵明辉 中国 北京 北京

2

9

上海长征医院 郁胜强 中国 上海 上海

3

0

Apex Medical

Research, Inc.

Ahmed

Azazuddin

United

States

Illinois Chicago

3

1

Farmington

Research LLC

Amin Mohammad United

States

Missouri Farmington

3

2

Biolab Research,

LLC

Belledonne

Mario

United

States

MARYLAND Rockville

3

3

California

Institute of

Renal Research

Belo Diogo United

States

CALIFORNIA Chula Vista

3

4

Academic Medical

Research

Institute

El-Shahawy

Mohamed

United

States

California Los Angeles

3

5

California

Institute of

Renal Research

Fadda George United

States

California La Mesa

3

6

East West

Medical Research

Fitz-Patrick

David

United

States

Hawaii Honolulu

Institute

3

7

Brookview Hills

Research

Associates, LLC

Greenwood

Gregory

United

States

North

Carolina

Winston-Sa

lem

3

8

Hypertension and

Renal Research

Group

Herman

Theodore

United

States

New York Orchard

Park

3

9

North Shore

Diabetes and

Endocrine

Associates

Hershon

Kenneth

United

States

NEW YORK New Hyde

Park

4

0

North America

Research

Institute

Jamal Aamir United

States

CALIFORNIA Azusa

4

1

Metabolic

Research

Institute, Inc.

Kaye William United

States

FLORIDA West Palm

Beach

4

2

Northeast

Clinical

Research

Centers, LLC

Kopyt Nelson United

States

Pennsylvan

ia

Bethlehem

4

3

South Texas

Kidney

Specialists, PA

Mangoo-Karim

Roberto

United

States

Texas McAllen

4

4

Model Clinical

Research

Mersey James United

States

MARYLAND Baltimore

4

5

Hurley Medical

Center

Osama Sayed United

States

Michigan Flint

4

6

Clinical

Advancement

Center, PLLC

Pergola Pablo United

States

Texas San Antonio

4

7

Creighton

University

Medical Center

Rendell Marc United

States

Nebraska Omaha

4

8

Tulane

University

Health Sciences

Center

Simon Eric United

States

Louisiana New Orleans

4

9

Pines Clinical

Research, Inc.

Zeig Steven United

States

Florida Pembroke

Pines

5

0

Metrolina

Nephrology

Associates, PA

Chuang Peale United

States

North

Carolina

Charlotte

5 Sansum Clinic Elder John United California Santa

1 States Barbara

5

2

Desert Medical

Group, Inc.

Jardula

Michael

United

States

California Palm

Springs

5

3

Texas Tech

University

Health Sciences

Center

Ahmed Vaqar United

States

Texas Lubbock

5

4

George

Washington

University

Medical Faculty

Associates

Cohen Scott United

States

District of

Columbia

Washington

5

5

MetroHealth

Medical Center

Sedor John United

States

Ohio Cleveland

5

6

Rhode Island

Hospital

Bayliss George United

States

Rhode

Island

Providence

5

7

Axis Clinical

Trials

Hazan Lydie United

States

California Los Angeles

5

8

FPA Family

Health Care

Clinical Studies

Link Michael United

States

FLORIDA Kissimmee

5

9

Down East

Medical

Associates, P.A.

Lawrence Mary United

States

North

Carolina

Morehead

6

0

University of

Cincinnati,

College of

Medicine

El-Khatib

Mahmoud

United

States

Ohio Cincinnati

6

1

Gwinnett

Biomedical

Research

Lalwani Tarik United

States

Georgia Lawrencevi

lle

6

2

San Diego

Coastal

Endocrinology

Group, aMC

Argoud Georges United

States

California Chula Vista

6

3

PrimeCare

Medical Group

Doshi Ankur United

States

Texas Houston

6

4

Green Clinic LLC Nammour

Michael

United

States

Louisiana Ruston

6

5

Eastern

Nephrology

Associates, PLCC

Montero Manuel United

States

North

Carolina

New Bern

6

6

St. Jude

Hospital

Gilbert John United

States

California Fullerton

6

7

University of

Chicago

Bakris George United

States

Illinois Chicago

6

8

Emory University

Hospital

Guasch Antonio United

States

Atlanta Georgia

6

9

Providence

Clinical

Research

Sligh Teresa United

States

North

Hollywood

California

7

0

University of

Tennessee Health

Sciences Center

Kovesdy Csaba United

States

Memphis Tennessee

7

1

Hypertension and

Nephrology

Associates PA

Liss Kenneth United

States

Eatontown New Jersey

7

2

Endocrinology

Associates, Inc.

Christofides

Elena

United

States

Columbus Ohio

7

3

Louisiana State

University

Health Sciences

Center

Reisin Efrain United

States

New Orleans Louisiana

7

4

Clinical

Research

Development

Associates, LLC

Scott David United

States

Rosedale New York

7

5

University of

Mississippi

Medical Center

Juncos Luis United

States

Jackson Mississipp

i

7

6

Capital

Nephrology

Medical Group

Atray Naveen United

States

Sacramento California

7

7

East Carolina

University

Nephrology

Research

Hames Melanie United

States

Greenville North

Carolina

7

8

Boice-Willis

Clinic, P.A.

Jere Charles United

States

Rocky Mount North

Carolina

7

9

My Kidney

Center, LLC

Bedros Fadi United

States

Manhattan Kansas

8

0

Jersey Shore

University

Medical Center

Asnani Sunil United

States

Neptune New Jersey

8

1

Sierra Nevada

Nephrology

Consultants

Vicks Steven United

States

Reno Nevada

8 Stamford Brown Eric United Connecticu Stamford

2 Nephrology States t

8

3

Briggs Clinical

Research, LLC

Gaona, Sr.

Raul

United

States

Texas San Antonio

8

4

National

Research

Institute

Frias Juan United

States

California Los Angeles

8

5

Cooper

Nephrology

McFadden

Christopher

United

States

New Jersey Camden

8

6

Herman Clinical

Research, LLC

Herman Lee United

States

Georgia Suwanee

8

7

Columbia

Nephrology

Associates, PA

Buerkert John United

States

South

Carolina

Columbia

8

8

Apex Medical

Research,

MI,Inc.

Arif Ahmed United

States

Michigan Flint

8

9

Alta

Pharmaceutical

Research Center,

Inc.

Miller Alan United

States

GEORGIA Dunwoody

9

0

University of

Utah

Beddhu

Srinivasan

United

States

Utah Salt Lake

City

9

1

Central Florida

Internists

Khan Muhammad United

States

Florida St. Cloud

9

2

Remedica LLC Tatu Horia United

States

Michigan Rochester

9

3

Lucita M. Cruz MD Cruz Lucita United

States

California Norwalk

9

4

Knoxville Kidney

Center, PLLC

Newman George United

States

Tennessee Knoxville

9

5

West Virginia

University,

School of

Medicine

Schmidt

Rebecca

United

States

West

Virginia

Morgantown

9

6

Nephrology

Associates of

Northern

Virginia, Inc.

Assefi Ali United

States

VIRGINIA Fairfax

9

7

Kaufman, New

York, NY

Kaufman Allen United

States

New York New York

9

8

Lee County

Internal

Medicine

Associates

Bohm Guillermo United

States

Florida Fort Myers

9

9

California

Institute of

Renal Research

Boiskin Mark United

States

CALIFORNIA San Diego

1

0

0

Nephrology

Associates P.C.

Brantley Roman United

States

Alabama Birmingham

1

0

1

Houston

Nephrology Group

Chatha Rupi United

States

Texas Houston

1

0

2

Hanson Clinical

Research Center

Hanson Lenita United

States

Florida Port

Charlotte

1

0

3

South Florida

Nephrology

Group, PA

Jacob Radu United

States

Florida Coral

Springs

1

0

4

Seacoast Kidney

and Hypertension

Specialists,

PLLC

Joshi Sucharit United

States

New

Hampshire

Portsmouth

1

0

5

Oregon Health

and Science

University

Rueda Jose United

States

Oregon Portland

1

0

6

Palm Research

Center, Inc.

Nakhle Samer United

States

Nevada Las Vegas

1

0

7

Preferred

Primary Care

Physicians, Inc

Purighalla

Raman

United

States

Pennsylvan

ia

Pittsburgh

1

0

8

Anne Arundel

Medical Center

(AAMC)

Welker James United

States

Maryland Annapolis

1

0

9

Diagnostic

Clinic Of

Houston

Varghese

Freemu

United

States

Texas Houston

1

1

0

University of

Louisville

Jacobs

Alfred

United

States

Kentucky Louisville

1

1

1

Texas Health

Physicians Group

Arauz-Pacheco

Carlos

United

States

Texas Dallas

1

1

2

Thomas Jefferson

University

Hospital

Jabbour Serge United

States

Pennsylvan

ia

Philadelph

ia

1 Renal Medicine Kumar Jayant United New Mexico Albuquerqu

1

3

Associates States e

1

1

4

NYU Langone

Medical Center

Wissner-Green

e Loren

United

States

New York New York

1

1

5

East Texas

Nephrology

Associates

Nazeer Imran United

States

Texas Lufkin

1

1

6

Rogosin

Institute

Perlman Alan United

States

New York New York

1

1

7

Drexel

University

College of

Medicine

Ahmed Ziauddin United

States

Pennsylvan

ia

Philadelph

ia

1

1

8

Arizona Kidney

Disease and

Hypertension

Center

Desai Sachin United

States

Arizona Phoneix

1

1

9

Carolina Health

Specialists

Eagerton

Donald

United

States

South

Carolina

Myrtle

Beach

1

2

0

Penn State,

Milton S.

Hershey Medical

Center

Farooq Umar United

States

Pennsylvan

ia

Hershey

1

2

1

Diabetes

Associates

Medical Group

Madu Ivy-Joan United

States

California Orange

1

2

2

Fletcher Allen

Health Care,

Burlington,

Vermont

Solomon

Richard

United

States

Vermont Burlington

1

2

3

APEX Research of

Riverside

Lee Joseph United

States

CALIFORNIA Riverside

1

2

4

Univ of Texas

Health Science

Center at San

Antonio

Bansal Shweta United

States

Texas San Antonio

1

2

5

University of

New Mexico

Adolphe Allen United

States

New Mexico Albuquerqu

e

1 University of Dixon Brad United Iowa Iowa City

2

6

Iowa States

1

2

7

Temple

University

Hospital

Benjamin

Joseph

United

States

Pennsylvan

ia

Philadelph

ia

1

2

8

North Texas

Endocrine Center

Bressler Peter United

States

Texas Dallas

1

2

9

Northside

Internal

Medicine DEXA

Cathcart

Harold

United

States

Washington Spokane

1

3

0

Kaiser

Foundation

Health Plan of

Georgia, Inc.

Muoneke

Rosemary

United

States

Georgia Duluth

1

3

1

Atlanta

Nephrology

Referral Center

Sharon Zeev United

States

Georgia Decatur

1

3

2

San Antonio

Kidney Disease

Center

Physicians

Group, PLLC

Gouge Steven United

States

Texas San Antonio

1

3

3

Ladan

Golestaneh, MD,

MS

Golestaneh

Laden

United

States

New York Bronx

1

3

4

Maine Research

Associates

Weiss Robert United

States

Maine Auburn

1

3

5

Mohammed Ismail,

MD, Inc.

Ismail

Mohammad

United

States

California Paramount

1

3

6

Four Rivers

Clinical

Research, Inc.

De La Rosa,

Raymond

United

States

Kentucky Paducah

1

3

7

Internal

Medicine

Specialists

Rodriguez-Ara

ya Eduardo

United

States

Louisiana New Orleans

1

3

8

Community

Clinical

Research Center

Bakdash Wa'el United

States

Indiana Anderson

1

3

9

Independent

Clinical

Research

Butt Salman United

States

Texas McKinney

1

4

0

Yale Univ School

of Medicine

Dahl Neera United

States

Connecticu

t

New Haven

1

4

1

San Marcus

Research Clinic,

Inc.

Acosta Idalia United

States

Florida Miami

1

4

2

Compass

Research, LLC

Stoica

George

United

States

Florida Orlando

1

4

3

Texas Renal Care Ijaz Adeel United

States

TEXAS Greenville

1

4

4

Pines Care

Research Center,

Inc.

Moya

Hechevarria

Jaynier

United

States

Florida Pembroke

Pines

1

4

5

Cleveland Clinic

Foundation

Taliercio

John

United

States

Ohio Cleveland

1

4

6

Ochsner Clinic

Foundation

Reichel Ronald United

States

Louisiana New Orleans

1

4

7

NY Clinical

Trials

Bloom Scott United

States

New York New York

1

4

8

Erie County

Medical Center

Gundroo Aijaz United

States

New York Buffalo

1

4

9

Angiocardiac

Care of Texas, PA

Karim Amin United

States

Texas Houston

1

5

0

SUNY Downstate

Medical Center

Markell

Mariana

United

States

New York Brooklyn

1

5

1

Sensenbrenner

Primary Care,

Charlotte, NC

Sensenbrenner

John

United

States

NORTH

CAROLINA

Charlotte

1

5

2

Pentucket

Medical

Associates, LLC

Dulude Emily United

States

Massachuse

tts

Haverhill

1

5

3

Crescent City

Clinical

Research Center,

LLC

Wise Jonathan United

States

Louisiana Metairie

1 Diagnostic Tulloch Brian United Texas Houston

5

4

Clinic Of

Houston

States

1

5

5

National

Institute of

Clinical

Research

Joshi Sudhir United

States

California Bakersfiel

d

1

5

6

Kidney

Innovations

Levine Andrew United

States

Texas Weslaco

1

5

7

Renaissance

Renal Research

Institute, LLC

Khairullah

Quresh

United

States

Michigan Detroit

1

5

8

Kidney Care

Center

Awua-Larbi

Stella

United

States

Illinois Joliet

1

5

9

Kidney and

Hypertension

Care Center

Khan Mehreen United

States

Texas Houston

1

6

0

Meridien

Research Group

Chaykin Louis United

States

Florida Bradenton

1

6

1

Premier Research

Associate, Inc

De la Calle

Gilda

United

States

Florida Hialeah

1

6

2

Nephrology

Associates

Research Center

Minga Todd United

States

Florida Panama City

1

6

3

NorthShore

University

HealthSystem

Sarav Menaka United

States

Illinois Evanston

1

6

4

Innovative

Medical Research

of South

Florida, Inc.

Schlessinger

Fabiola

United

States

Florida Aventura

1

6

5

University of

Florida

Hall Karen United

States

Florida Gainesvill

e

1

6

6

Southern Utah

Kidney and

Hypertension

Center

Leon-Forero

Carlos

United

States

Utah Saint

George

1

6

7

AKDHC Medical

Research

Services, LLC

Nica Romanita United

States

Arizona Prescott

1

6

8

California Renal

Research

Network, LLC

Minasian Raffi United

States

California Glendale

1

6

9

Professional

Health Care of

Pinellas

Saba Fadi United

States

Florida St.

Petersburg

1

7

0

Clinical

Research of

Brandon, LLC

Alvarez German United

States

Florida Brandon

1

7

1

Audie L. Murphy

VA Hospital,

STVHCS

Fanti Paolo United

States

Texas San Antonio

1

7

2

Pentucket

Medical

Associates, LLC

Tarkan Joshua United

States

Massachuse

tts

Newburypor

t

1

7

3

VAMC Cincinnati Thakar

Charuhas

United

States

Ohio Cincinnati

1

7

4

Emory University

and Atlanta VA

Medical Center

Phillips

Lawrence

United

States

Georgia Decatur

1

7

5

Zablocki VA

Medical Center

Blumenthal

Samuel

United

States

Wisconsin Milwaukee

1

7

6

VA Long Beach

Healthcare

System

Levin Ellis United

States

CALIFORNIA Long Beach

1

7

7

CEREHA Elbert Alicia Argenti

na

Avellaneda Avellaneda

1

7

8

Instituto de

Investigaciones

Clinicas Bahia

Blanca

Vogel Daniel Argenti

na

Buenos

Aires

Buenos

Aires

1

7

9

Instituto de

Investigaciones

Medicas Alfredo

Lanari

Zucchini

Alfredo

Argenti

na

Buenos

Aires

Buenos

Aires

1

8

0

Consultorios

Asociados de

Endocrinologia /

Inv Clin

Aplicado

Maffei Laura Argenti

na

Buenos

Aires

Buenos

Aires

1 Hospital Greloni Argenti Buenos Buenos

8

1

Italiano de

Buenos Aires

Gustavo na Aires Aires

1

8

2

CEMIC (Centro

Educacion Medica

e Investigacion

Clinica)

Diaz Carlos Argenti

na

Buenos

Aires

Buenos

Aires

1

8

3

Instituto

Latinoamericano

de

Investigaciones

Medicas

Ulla Maria Argenti

na

Cordoba Cordoba

1

8

4

Fundacion J.

Robert Cade

Juncos Luis Argenti

na

Cordoba Cordoba

1

8

5

Blossom DMO Garcia Nestor Argenti

na

Cordoba Cordoba

1

8

6

Instituto

Cardiologia de

Corrientes Juana

Francisca Cabral

Farias Eduardo Argenti

na

Corrientes Corrientes

1

8

7

Centro de Salud

Renal Junin

S.R.L.

Vallejos

Augusto

Argenti

na

Junin Junin

1

8

8

Instituto de

Nefrologia

Pergamino S.R.L.

Cusumano Ana Argenti

na

Pergamino Pergamino

1

8

9

Investigaciones

Clinicas Tucuman

Santos Juan Argenti

na

San Miguel

de Tucuman

San Miguel

de Tucuman

1

9

0

Royal Prince

Alfred Hospital

Chadban Steve Austral

ia

New South

Wales

Camperdown

1

9

1

Renal Research Roger Simon Austral

ia

New South

Wales

Gosford

1

9

2

Liverpool

Hospital

Suranyi

Michael

Austral

ia

New South

Wales

Liverpool

1

9

3

The Prince of

Wales Hospital

Endre Zoltan Austral

ia

New South

Wales

Randwick

1

9

Royal North

Shore Hospital

Pollock Carol Austral

ia

New South

Wales

St Leonards

4

1

9

5

Nambour General

Hospital

Gray Nicholas Austral

ia

Queensland Nambour

1

9

6

Southern

Adelaide

Diabetes

Endocrine

Services

Stranks

Stephen

Austral

ia

South

Australia

Daw Park

1

9

7

Royal Melbourne

Hospital

Toussaint

Nigel

Austral

ia

Victoria Parkville

1

9

8

Fremantle

Hospital

Davis Tim Austral

ia

Western

Australia

Fremantle

1

9

9

Sir Charles

Gairdner

Hospital

Chan Doris Austral

ia

Western

Australia

Nedlands

2

0

0

Box Hill

Hospital

Fraenkel

Margaret

Austral

ia

Box Hill Box Hill

2

0

1

Concord

Repatriation and

General Hospital

Gallagher

Martin

Austral

ia

Concord Concord

2

0

2

Launceston

General Hospital

Cooke Duncan Austral

ia

Launceston Launceston

2

0

3

John Hunter

Hospital

Acharya

Shamasunder

Austral

ia

New Lambton New Lambton

2

0

4

St. Vincents

Hospital

Melbourne

MacIsaac

Richard

Austral

ia

Victoria Victoria

2

0

5

CHR de la

Citadelle

Warling Xavier Belgium Liege Liege

2

0

6

Cliniques

Universitaires

Saint Luc

Jadoul Michel Belgium Brussels Brussels

2

0

7

Onze Lieve Vrouw

Hospital

Van Vlem Bruno Belgium Aalst Aalst

2

0

Universitair

Ziekenhuis

Gillard Pieter Belgium Leuven Leuven

8 Leuven

2

0

9

Centro de

Estudos em

Diabetes e

Hipertensao

Forti Adriana

Costa

Brazil Ceara Fortaleza

2

1

0

Hospital Geral

de Goiania

Rassi Nelson Brazil Goias Goiania

2

1

1

Hospital Sao

Lucas-PUCRS

D'Avila

Domingos

Brazil Rio Grande

do Sul

Porto

Alegre

2

1

2

Irmandade da

Santa Casa de

Misericordia de

Porto Alegre

Keitel Elizete Brazil Rio Grande

do Sul

Porto

Alegre

2

1

3

Clinica de

Endocrinologia

Fraige Filho

Fadlo

Brazil Sao Paulo Sao Paulo

2

1

4

University

Federal de Sao

Paulo

Chacra Antonio Brazil Sao Paulo Sao Paulo

2

1

5

IPEC - Instituto

de Pesquisa

Clinica

Salles, Joao

Eduardo

Brazil Sao Paulo Sao Paulo

2

1

6

Instituto Dante

Pazzanese de

Cardiologia

Amodeo Celso Brazil Sao Paulo Sao Paulo

2

1

7

The Bailey

Clinic

Bailey Gordon Canada Alberta Red Deer

2

1

8

St. Paul's

Hospital

Levin Adeera Canada British

Columbia

Vancouver

2

1

9

Clinical

Research

Solutions Inc.

Jolly

Shivinder

Canada Ontario Kitchener

2

2

0

OTT Healthcare

Inc.

Tam Paul Canada Ontario Scarboroug

h

2

2

1

Toronto East

General Medical

Centre

Chow Stephen Canada Ontario East York

2

2

LMC Diabetes and

Endocrinology

Bajaj

Harpeet

Canada Ontario Brampton

2

2

2

3

LMC Diabetes and

Endocrinology

Khandwala

Hasnain

Canada Ontario Etobicoke

2

2

4

LMC Diabetes and

Endocrinology

Aronson Ronnie Canada Ontario Toronto

2

2

5

Co-Medica

Research

Network, Inc

Steele Andrew Canada Ontario Courtice

2

2

6

Humber River

Regional

Hospital

Nesrallah

Gihad

Canada Ontario Toronto

2

2

7

JBN Medical

Diagnostic

Services Inc.

Berlingieri

Joseph

Canada Ontario Burlington

2

2

8

St. Joseph's

Healthcare

Rabbat

Christian

Canada Ontario Hamilton

2

2

9

Medicor Research

Inc.

Goluch Richard Canada Ontario Sudbury

2

3

0

Centre de Sante

et de Services

Sociaux

Champlain

Cournoyer

Serge

Canada Quebec Greenfield

Park

2

3

1

Hospital

Maisonneuve-Ros

emont

Pichette

Vincent

Canada Quebec Montreal

2

3

2

CHUM - Hopital

Saint-Luc

Roy Louise Canada Quebec Montreal

2

3

3

CALMED Castillo

Alvaro

Chile La Serena La Serena

2

3

4

Servicios

Medicos Godoy

Limitada

Godoy Gonzalo Chile Santiago Santiago

2

3

5

Biomedica

Research Group

Gutierrez

Vicente

Chile Santiago Santiago

2

3

6

Hospital Clinico

Regional Dr.

Guillermo Grant

Munoz Rodrigo Chile Concepcion Concepcion

Benavente

2

3

7

Hospital del

Salvador

Gonzalez

Fernando

Chile Providenci

a, Santiago

Providenci

a, Santiago

2

3

8

Petr Bucek

s.r.o.

Bucek Petr Czech

Republi

c

Frydek-Mis

tek

Frydek-Mis

tek

2

3

9

Masarykova

mestska

nemocnice

Oplustilova

Alexandra

Czech

Republi

c

Jilemnice Jilemnice

2

4

0

Fakultni

Nemocnice

Ostrava

Valkovsky Ivo Czech

Republi

c

Ostrava-Po

ruba

Ostrava-Po

ruba

2

4

1

Diabetologicka

ambulance

Pavlickova

Jirina

Czech

Republi

c

Pardubice Pardubice

2

4

2

PeMedica.CZ,

s.r.o.

Petr Martin Czech

Republi

c

Prague Prague

2

4

3

Vseobecna

fakultni

nemocnice v

Praze (VFN)

Tesar Vladimir Czech

Republi

c

Prague Prague

2

4

4

Fakultni

Nemocnice

Kralovske

Vinohrady FNKV

Rychlik Ivan Czech

Republi

c

Prague 10 Prague 10

2

4

5

Milan Kvapil

s.r.o.

Bartaskova

Dagmar

Czech

Republi

c

Prague 4 Prague 4

2

4

6

Nemocnice Trebic Chmelickova

Hana

Czech

Republi

c

Trebic Trebic

2

4

7

Slagelse

Hospital

Gaede Peter Denmark Slagelse Slagelse

2

4

8

University

Hospital of

Frederiskberg

Urhammer Soren Denmark Frederiksb

erg

Frederiksb

erg

2

4

9

Roskilde

Hospital

Ostergaard Ove Denmark Rosklide Rosklide

2

5

Regional

Hospital

Oczachowska-K

ulik, Anna Ewa

Denmark Holstebro Holstebro

0 Holstebro

2

5

1

Aarhus

University

Hospital, Skejby

Povlsen Johan Denmark Aarhus C Aarhus C

2

5

2

Steno Diabetes

Center

Rossing Peter Denmark Gentofte Gentofte

2

5

3

Terveystalo Oulu Strand Jorma Finland Oulu Oulu

2

5

4

Tampere

University

Hospital

Lahtela Jorma Finland Tampere Tampere

2

5

5

Turku University

Hospital

Kantola Ilkka Finland Turku Turku

2

5

6

CHU de Grenoble -

Hopital Albert

Michallon

Zaoui Philippe France Grenoble Grenoble

2

5

7

CHU de Nice Esnault

Vincent

France Nice Nice

2

5

8

Clinique du

Landy

Urena Torres

Pablo

France Saint Ouen Saint Ouen

2

5

9

Hopital de la

Conception

Dussol

Bertrand

France Marseille Marseille

2

6

0

Hospital

European,

Georges Pompidou

Thervet Eric France Paris Paris

2

6

1

Dimokritio

University

Hospital of

Alexandroupoli

Passadakis

Ploumis

Greece Alexandrou

polis

Alexandrou

polis

2

6

2

Interbalkan

Medical Center

Papadimitriou

Menelaos

Greece Thessaloni

ki

Thessaloni

ki

2

6

3

University

General Hospital

of Patras

Goumenos

Dimitrios

Greece Patras Patras

2

6

4

University

General Hospital

Liakopoulos

Vasilios

Greece Thessaloni

ki

Thessaloni

ki

2

6

5

University

General Hospital

of Ioannina

Siamopoulos

Konstantinos

Greece Ionnina Ionnina

2

6

6

SISMANOGLEIO

General Hospital

of Komotini

Mavromatidis

Konstantinos

Greece Komotini Komotini

2

6

7

General Hospital

of Athens,

Evangelismos

Apostolou

Theofanis

Greece Athens Athens

2

6

8

Universitaetskl

inikum Aachen

Muehlfeld Anja Germany Aachen Aachen

2

6

9

Klinische

Forschung Berlin

GbR

Schenkenberge

r Isabella

Germany Berlin Berlin

2

7

0

Charite Campus

Mitte

Budde

Klemens

Germany Berlin Berlin

2

7

1

Universitaetkli

nikum Dresden

Hugo Christian Germany Dresden Dresden

2

7

2

Studienzentrum

Karlstrasse GmbH

Dellanna

Frank-Hans

Germany Duesseldor

f

Duesseldor

f

2

7

3

St.

Josefskrankenha

us

Hasslacher

Christoph

Germany Heidelberg Heidelberg

2

7

4

Nephrologisches

Zentrum

Pistrosch

Frank

Germany Hoyerswerd

a

Hoyerswerd

a

2

7

5

Universitaetskl

inikum Jena

Wolf Gunter Germany Jena Jena

2

7

6

Ludwig

Maximiliam

Universitaet

Muenchen

Vielhauer

Volker

Germany Munich Munich

2

7

7

Diabetologische

Schwerpunktprax

is Pirna

Kosch

Christine

Germany Pirna Pirna

2

7

8

Bieler, Riesa,

DE

Bieler Tasso Germany Riesa Riesa

2 Diabetologische Segiet Thomas Germany Speyer Speyer

7

9

Schwerpunktprax

is

2

8

0

Robert-Bosch-Kr

ankenhaus

Alscher Mark Germany Stuttgart Stuttgart

2

8

1

Universitaetskl

inikum Wuerzburg

Wanner

Christoph

Germany Wuerzburg Wuerzburg

2

8

2

Cork University

Hospital

Eustace Joesph Ireland Cork Cork

2

8

3

St. Vincent's

University

Hospital

O'Shea Donal Ireland Dublin 4 Dublin 4

2

8

4

The Adelaide and

Meath Hospital

Lavin Peter Ireland Dublin 24 Dublin 24

2

8

5

Connolly

Hospital

Sreenan Seamus Ireland Dublin 15 Dublin 15

2

8

6

Maccabi Health

Services

Cohen Josef Israel Rishon Le

zion

Rishon Le

zion

2

8

7

Ziv Medical

Center

Adawi Faiad Israel Safed Safed

2

8

8

Ha'Emek Medical

Center

Mazen Elias Israel Afula Afula

2

8

9

Carmel Medical

Center

Frajewicki

Victor

Israel Haifa Haifa

2

9

0

Barzilai Medical

Center

Yagil Yoram Israel Ashkelon Ashkelon

2

9

1

The Edith

Wolfson Medical

Center

Bar-Dayan

Yosefa

Israel Holon Holon

2

9

2

Meir Medical

Center

Nacasch

Naomi

Israel Kfar Saba Kfar Saba

2

9

3

IRCCS Fondazione

Salvatore

Maugeri

Esposito Ciro Italy Pavia Pavia

2

9

4

Azienda ASST

Paga Giovanni

XXIII

Ruggenenti

Piero

Italy Bergamo Bergamo

2

9

5

Azi Soc

Sanitaria

Territoriale

Rombola

Giuseppe

Italy Varese Varese

2

9

6

Azienda

Ospedaliera

Sant' Andrea

Pugliese

Giuseppe

Italy Rome Rome

2

9

7

Universita della

Campania Luig

Capasso

Giovabattista

Italy Naples Naples

2

9

8

Ospedale S.

Maria della

Pieta di Naples

Nappi Felice Italy Naples Naples

2

9

9

Policlinico

Universitario

degli Federico

II di Naples

Russo Domenico Italy Naples Naples

3

0

0

Azienda

Ospedaliera

Bianchi

Melacrino

Morelli

Marino

Francesco

Italy Reggio

Calabria

Reggio

Calabria

3

0

1

Nakadori General

Hospital

Awasaki

Hiroshi

Japan Akita-shi Akita-shi

3

0

2

National

Hospital

Organization

Asahikawa

Medical Center

Hirano

Fuminori

Japan Asahikawa-

shi

Asahikawa-

shi

3

0

3

Shimizu Internal

Medicine Clinic

Taya Noriyasu Japan Asahikawa-

shi

Asahikawa-

shi

3

0

4

National

Hospital

Organization

Chiba-East-Hosp

ital

Nishimura

Motonobu

Japan Chiba-shi Chiba-shi

3

0

5

Fukuoka

University

Chikushi

Hospital

Kobayashi

Kunihisa

Japan Chikushino

-shi

Chikushino

-shi

3

0

6

Kyushu Central

Hospital of

Mutual Aid

Association

Goto Daisuke Japan Fukuoka Fukuoka

3

0

7

Japanese Red

Cross Fukuoka

Hospital

Sasaki

Nobuhiro

Japan Fukuoka-sh

i

Fukuoka-sh

i

3

0

8

Funabashi

Municipal

Medical Center

Iwaoka Hideaki Japan Fukuyama-s

hi

Fukuyama-s

hi

3

0

9

Anzai Clinic Anzai Jiichi Japan Hakodate Hakodate

3

1

0

Harada Clinic Harada

Hiroyuki

Japan Hakodate-s

hi

Hakodate-s

hi

3

1

1

Takahashi

Hospital, Social

Medical

Corporation

Tsutsui

Masahiro

Japan Hakodate-s

hi

Hakodate-s

hi

3

1

2

Hamamatsu

Medical Center

Nagayama Koji Japan Hamamatsu-

shi

Hamamatsu-

shi

3

1

3

Higashihiroshim

a Medical Center

Kishimoto

Rui

Japan Higashihir

oshima

Higashihir

oshima

3

1

4

Iwata City

Hospital

FURUYA

Ryuichi

Japan Iwata-shi Iwata-shi

3

1

5

Rinku General

Medical Center

KASHINE

Susumu

Japan Izumisano-

shi

Izumisano-

shi

3

1

6

Shimane

University

Hospital

Yamamoto

Masahiro

Japan Izumo Izumo

3

1

7

Tempozan Clinic

of Internal

Medicine

Hashiguchi

Yasuhiro

Japan Kagoshima Kagoshima

3

1

8

Kawanishi City

Hospital

Ueda

Shinichiro

Japan Kawanishi-

shi

Kawanishi-

shi

3

1

9

St. Marianna

University

School of

Shibagaki Yugo Japan Kawasaki-s

hi

Kawasaki-s

hi

Medicine

Hospital

3

2

0

Kokura Memorial

Hospital

Kanai

Hidetoshi

Japan Kitakyushu Kitakyushu

3

2

1

Kobe City

Medical Center

West Hospital

Nakamura

Takehiro

Japan Kobe-shi Kobe-shi

3

2

2

Showa General

Hospital

Fujita Akira Japan Kodaira-sh

i

Kodaira-sh

i

3

2

3

Itabashi Clinic Itabashi Naoki Japan Koga-shi Koga-shi

3

2

4

Koshigaya

Municipal

Hospital

Makita

Yuichiro

Japan Koshigaya Koshigaya

3

2

5

Dokkyo Medical

University

Koshigaya

Hospital

Takeda Tetsuro Japan Koshigaya-

shi

Koshigaya-

shi

3

2

6

Kumamoto Medical

Center

ONO Keiko Japan Kumamoto-s

hi

Kumamoto-s

hi

3

2

7

Kawasaki Medical

School Hospital

Kashihara

Naoki

Japan Kurashiki-

shi

Kurashiki-

shi

3

2

8

St. Mary's

Hospital

SATO Yuichi Japan Kurume-shi Kurume-shi

3

2

9

Rakuwakai Otowa

Hosptial

YAMAGUCHI

Yukinari

Japan Kyoto Kyoto

3

3

0

Kyoto City

Hospital

Iehara

Noriyuki

Japan Kyoto-shi Kyoto-shi

3

3

1

Takeda General

Hospital

Azuma Nobuyuki Japan Kyoto-shi Kyoto-shi

3

3

2

Matsue Red Cross

Hospital

Sato Toshiaki Japan Matsue-shi Matsue-shi

3

3

Saiseikai

Matsuyama

Miyaoka

Hiroaki

Japan Matsuyama-

shi

Matsuyama-

shi

3 Hospital

3

3

4

Chita Kosei

Hospital

Nimura

Toshinori

Japan Mihama-cho Mihama-cho

3

3

5

Miyazaki

Prefectural

Miyazaki

Hospital

Ikeda Naoko Japan Miyazaki-s

hi

Miyazaki-s

hi

3

3

6

Ato Internal

Medicine Clinic

Ato Keita Japan Muroran Muroran

3

3

7

Chubu Rosai

Hospital

Nakashima

Eitaro

Japan Nagoya-shi Nagoya-shi

3

3

8

Meitetsu

Hospital

Okamoto Hideki Japan Nagoya-shi Nagoya-shi

3

3

9

NHO Nagoya

Medical Center

Yambe Yuko Japan Nagoya-shi Nagoya-shi

3

4

0

Nakakinen Clinic Osonoi Takeshi Japan Naka Naka

3

4

1

Saiseikai

Niigata Daini

Hospital

Suzuki

Katsunori

Japan Niigata-sh

i

Niigata-sh

i

3

4

2

Kobari General

Clinic

Watanabe

Shuichi

Japan Noda Noda

3

4

3

Jiyugaoka Yamada

Clinic

Yamada

Daishiro

Japan Obihiro Obihiro

3

4

4

Obihiro Dai-ichi

Hospital

Sakai Takashi Japan Obihiro-sh

i

Obihiro-sh

i

3

4

5

Takagi Hospital Ono Yasuhiro Japan Okawa-shi Okawa-shi

3

4

6

Osaka Gyoumeikan

Hospital

Makino Shinya Japan Osaka Osaka

3

4

7

Osaka General

Medical Center

Umayahara

Yutaka

Japan Osaka-shi Osaka-shi

3

4

8

Otsu Municipal

Hospital

Isono Motohide Japan Otsu-shi Otsu-shi

3

4

9

Ibaraki Seinan

Medical Center

Hospital

Iitsuka

Tadashi

Japan Sakai-mach

i

Sakai-mach

i

3

5

0

Asama General

Hospital

Naka Motoji Japan Saku-shi Saku-shi

3

5

1

Sanuki Municipal

Hospital

Inoue

Toshihiko

Japan Sanuki-shi Sanuki-shi

3

5

2

Sapporo Medical

Center NTT EC

Nagai Sou Japan Sapporo-sh

i

Sapporo-sh

i

3

5

3

Manda Memorial

Hospital

Tsuchida

Kenichi

Japan Sapporo-sh

i

Sapporo-sh

i

3

5

4

Suruga Clinic Yamauchi Akira Japan Shizuoka Shizuoka

3

5

5

Shunan City

Shinnanyo

Hospital

Matsutani

Akira

Japan Shunan-shi Shunan-shi

3

5

6

Takamatsu Red

Cross Hospital

ISHIKO

Tamayo

Japan Takamatsu Takamatsu

3

5

7

Takatsuki Red

Cross Hospital

Kaneko Shizuka Japan Takatsuki-

shi

Takatsuki-

shi

3

5

8

Tamana Central

Hospital

Matsuda

Hirofumi

Japan Tamana-shi Tamana-shi

3

5

9

Tokushima

University

Hospital

Matsuhisa

Munehide

Japan Tokushima Tokushima

3

6

0

Tokyo Kamata

Medical Center

TAKEMOTO

Ikutake

Japan Tokyo Tokyo

3

6

1

National Center

for Global

Health and

Medicine

Hospital

TSUJIMOTO

Tetsuro

Japan Tokyo Tokyo

3

6

2

MAKITA General

Hospital

Kosuge

Keiichiro

Japan Tokyo Tokyo

3

6

3

The Institute

for Adult

Diseases

Onishi Yukiko Japan Tokyo Tokyo

3

6

4

Tokyo-Eki

Center-Building

Clinic

Kiyosue

Arihiro

Japan Tokyo Tokyo

3

6

5

JA Toride

Medical Center

Maeda

Yoshitaka

Japan Toride-shi Toride-shi

3

6

6

Toyota Memorial

Hospital

Shinoda Junji Japan Toyota-shi Toyota-shi

3

6

7

Mie Central

Medical Center

Tanaka

Tsuyoshi

Japan Tsu Tsu

3

6

8

Fujii Clinic Fujii Shinya Japan Ube Ube

3

6

9

National

Hospital

Organization

Shinshu Ueda

Medical Center

Tanaka Yukio Japan Ueda Ueda

3

7

0

Urasoe Sogo

Hospital

Ishikawa Kazuo Japan Urasoe-shi Urasoe-shi

3

7

1

Okamoto Internal

Medicine Office

Imura Mitsuo Japan Yaizu Yaizu

3

7

2

National

Hospital

Organization

Yokohama Medical

Center

Ujihara Makoto Japan Yokohama-s

hi

Yokohama-s

hi

3

7

3

Tokui Internal

Medicine Clinic

Tokui Mikiya Japan Yokohama-s

hi

Yokohama-s

hi

3

7

4

Nakajima Naika

Clinic

MUKASA Koji Japan Yokosuka-s

hi

Yokosuka-s

hi

3 Korea University Kim Nan Hee Korea, Ansan Ansan

7

5

Ansan Hospital Republi

c Of

3

7

6

Korea University

Ansan Hospital

Cha Dae-Ryong Korea,

Republi

c Of

Ansan Ansan

3

7

7

Soonchunhayng

University

Bucheon Hospital

Mok Ji Oh Korea,

Republi

c Of

Bucheon-si Bucheon-si

3

7

8

Dong-A

University

Hospital

Suh Sung Korea,

Republi

c Of

Busan Busan

3

7

9

Inje University

Busan Paik

Hospital

Park Jeong

Hyun

Korea,

Republi

c Of

Busan Busan

3

8

0

Chungbuk

National

University

Hospital

Oh Tae Keun Korea,

Republi

c Of

Cheongju-s

i

Cheongju-s

i

3

8

1

Chuncheon Sacred

Heart Hospital

Choi Moon-Gi Korea,

Republi

c Of

Chuncheon Chuncheon

3

8

2

Kyungpook

National

University

Hospital

Lee In-Kyu Korea,

Republi

c Of

Daegu Daegu

3

8

3

Daegu Catholic

University

Medical Center

Shon Ho Sang Korea,

Republi

c Of

Daegu Daegu

3

8

4

Keimyung

University

Dongsan Hospital

Cho Ho Chan Korea,

Republi

c Of

Daegu Daegu

3

8

5

Yeungnam

University

Medical Center

Lee Hyoung Woo Korea,

Republi

c Of

Daegu Daegu

3

8

6

Chungnam

National

University

Hospital

Lee Kang-Wook Korea,

Republi

c Of

Daejeon Daejeon

3

8

7

Myongji Hospital Lee Jae Hyuk Korea,

Republi

c Of

Goyang Goyang

3

8

8

Hanyang

University Guri

Hospital

Yi, Joo Hark Korea,

Republi

c Of

Guri Guri

3

8

9

Chosun

University

Hospital

Kim Sang Yong Korea,

Republi

c Of

Gwangju Gwangju

3

9

0

Wonkwang

University

School Of

Medicine &

Hospital

Cho, Chung Gu Korea,

Republi

c Of

Iksan Iksan

3

9

1

Gachon

University Gil

Hospital

Kim Byung-Joon Korea,

Republi

c Of

Incheon Incheon

3

9

2

Jeju National

University

Hospital

Lee Sang Ah Korea,

Republi

c Of

Jeju-si Jeju-si

3

9

3

Chonbuk National

University

Hospital

Park Tae-Sun Korea,

Republi

c Of

Jeonju Jeonju

3

9

4

Pusan National

University

Hospital

Kim In-Joo Korea,

Republi

c Of

Pusan Pusan

3

9

5

Seoul National

University

Bundang Hospital

Jang Hak-Chul Korea,

Republi

c Of

Seongnam Seongnam

3

9

6

Bundang Cha

Hospital

Cho Yong-Wook Korea,

Republi

c Of

Seongnam Seongnam

3

9

7

Gangnam

Severance

Hospital

Ahn Chul Woo Korea,

Republi

c Of

Seoul Seoul

3

9

8

Hallym

University

Kangdong Sacred

Heart Hospital

Kim Doo-Man Korea,

Republi

c Of

Seoul Seoul

3

9

9

Samsung Medical

Center

Lee Moon-Kyu Korea,

Republi

c Of

Seoul Seoul

4

0

0

Seoul National

University

Hospital

Park Kyong-Soo Korea,

Republi

c Of

Seoul Seoul

4

0

1

Gangdong

Kyunghee

University

Hospital

Ahn Kyu Jeung Korea,

Republi

c Of

Seoul Seoul

4 Kyunghee Woo Jeong-Taek Korea, Seoul Seoul

0

2

University

Medical Center

Republi

c Of

4

0

3

The Catholic

Univ. of Korea

Seoul, St.

Mary's Hospital

Yoon Kun-Ho Korea,

Republi

c Of

Seoul Seoul

4

0

4

Korea Universtiy

Guro Hospital

Choi Kyung Korea,

Republi

c Of

Seoul Seoul

4

0

5

Korea University

Anam Hospital

Kim Sin-Gon Korea,

Republi

c Of

Seoul Seoul

4

0

6

The Catholic

University of

Korea St. Paul's

Hospital

Kim Byung Soo Korea,

Republi

c Of

Seoul Seoul

4

0

7

Asan Medical

Center

Kim Min Seon Korea,

Republi

c Of

Seoul Seoul

4

0

8

Severance

Hospital

Kim Beom Seok Korea,

Republi

c Of

Seoul Seoul

4

0

9

Ajou University

Hospital

Lee Kwan-Woo Korea,

Republi

c Of

Suwon Suwon

4

1

0

Uijeongbu St.

Mary's Hospital

Yoon Sun Ae Korea,

Republi

c Of

Uijeongbu Uijeongbu

4

1

1

Ulsan University

Hospital

Nam-Goong

II-Seong

Korea,

Republi

c Of

Ulsan Ulsan

4

1

2

Yonsei

University Wonju

Severance

Christian

Hospital

Chung Choon

Hee

Korea,

Republi

c Of

Wonju Wonju

4

1

3

Hospital

Selayang

Wong Hin Seng Malaysi

a

Batu Caves Batu Caves

4

1

4

Hospital Serdang Goh Bak Leong Malaysi

a

Kajang Kajang

4

1

University Sains

Malaysia

Mohamed

Mafauzy

Malaysi

a

Kota Bharu Kota Bharu

5

4

1

6

Hospital Raja

Perempuan Zainab

II

Hassen Wan

Hasnul Halimi

Malaysi

a

Kota Bharu Kota Bharu

4

1

7

Hospital Kuala

Lumpur

Ahmad Ghazali Malaysi

a

Kuala

Lumpur

Kuala

Lumpur

4

1

8

Hospital

Universiti

Kebangsaan

Malaysia

Sukor Norlela Malaysi

a

Kuala

Lumpur

Kuala

Lumpur

4

1

9

Hospital Tengku

Ampuan Afzan

Nik Ahmad Nik Malaysi

a

Kuantan Kuantan

4

2

0

Hospital Melaka Shalini

Vijayasingham

Malaysi

a

Melaka Melaka

4

2

1

Hospital Pulua

Pinang c/o

Penang Medical

College

Aziz Nor

Azizah

Malaysi

a

Pulau

Pinang

Pulau

Pinang

4

2

2

Hospital

Putrajaya

Hussein

Zanariah

Malaysi

a

Putrajaya Putrajaya

4

2

3

Hospital Tuanku

Jafaar

Adam Noor Malaysi

a

Seremban Seremban

4

2

4

Hospital Taiping Ramanathan GR Malaysi

a

Taiping Taiping

4

2

5

Hospital Taiping Vaithilingam

Indralingan

Malaysi

a

Taiping Taiping

4

2

6

Centro de

Investigacion

Clinica del

Pacifico

Leguizamo-Dim

as Aniceto

Mexico Acapulco Acapulco

4

2

7

Clinica San

Cosme

Chew Wong

Alfredo

Mexico Aguascalie

ntes

Aguascalie

ntes

4

2

8

Instituto de

Diabetes

Obesidad y

Nutricion S.C.

Sauque Reyna

Leobardo

Mexico Cuernavaca

, Morelos

Cuernavaca

, Morelos

4

2

9

Investigacion

Nefrologica S.C.

Bochicchio-Ri

cardelli

Tomasso

Mexico Cuernavaca

, Morelos

Cuernavaca

, Morelos

4

3

0

Instituto

Jalisciense de

Investigacion en

Diabetes

Obesidad

Gonzalez-Galv

ez Guillermo

Mexico Guadalajar

a

Guadalajar

a

4

3

1

Area Medica

SANEFRO

Renoirte Lopez

Karina

Mexico Guadalajar

a

Guadalajar

a

4

3

2

Instituto

Nacioanl de

Ciencias Medicas

Nutricion S.

Zubiran

Nino, Jose

Antonio

Mexico Mexico City Mexico City

4

3

3

Instituto

Nacional de

Cardiologia

Madero Rovalo

Magdalena

Mexico Mexico City Mexico City

4

3

4

Hospital

Universitario

Dr. Jose

Eleuterio

Gonzalez

Gonzalez

Gonzalez Jose

Mexico Monterrey,

N.L.

Monterrey,

N.L.

4

3

5

Hospital y

Clinica OCA

Rico Hernandez

Raul

Mexico Monterrey,

Nuevo Leon

Monterrey,

Nuevo Leon

4

3

6

Unidad de

Prevencion y

Atencion

Cardiometabolic

a (UPAC)

Carranza-Madr

igal Jaime

Mexico Morelia,

Michoacan

Morelia,

Michoacan

4

3

7

Hospital Central

Dr. Ignacio

Morones Prieto

Chevaile-Ramo

s Jose

Mexico San Luis

Potosi

San Luis

Potosi

4

3

8

Universitair

Medisch Centrum

Groningen

Gansevoort Ron Netherl

ands

Groningn Groningn

4

3

9

Albert

Schweitzer

Ziekenhuis

Smak Gregoor

Peter

Netherl

ands

Dordrecht Dordrecht

4

4

0

Ziekenhuis Groep

Twente

Laverman

Gozewijn

Netherl

ands

Almelo Almelo

4

4

1

Gelre Hospital

Apeldoorn

Barendregt JNM

(Jos)

Netherl

ands

Apeldoorn Apeldoorn

4

4

2

Meander Medisch

Centrum

Luik Peter Netherl

ands

Amersfoort Amersfoort

4

4

3

Auckland City

Hospital

Pilmore Helen New

Zealand

Auckland Auckland

4

4

4

Dunedin Hospital Schollum John New

Zealand

Dunedin Dunedin

4

4

5

Waikato Hospital Rabindranath

Kannaiyan

New

Zealand

Hamilton Hamilton

4

4

6

Taranaki Base

Hospital

Hayat Ashik New

Zealand

New

Plymouth

New

Plymouth

4

4

7

North Shore

Hospital

Miller Steven New

Zealand

Takapuna Takapuna

4

4

8

Instituto

Endocronolocigo

Farfan E.I.R.L

Farfan-Aspilc

ueta Julio

Peru Arequipa Arequipa

4

4

9

Exacta Lab SAC Burga Nunez

Jose

Peru Arequipa Arequipa

4

5

0

Instituto

Delgado de

Investigacion

Medica

Delgado-Butro

n Cesar

Peru Arequipa Arequipa

4

5

1

Hospital

Nacional Alberto

Sabogal

Sologuren

Herrada Orue

Benjamin

Peru Callao Callao

4

5

2

Hospital

Nacional Adolfo

Guevara Velasco

Essalud

Zea-Nunez

Carlos Antonio

Peru Cusco Cusco

4

5

3

Centro de

Investigacion y

Atencion

Cardiovascular

SAC.

Calderon

Ticona Jorge

Peru Lima Lima

4

5

4

Clinica de

Diabetes S.A.C.

Zapata-Rincon

Luis

Peru Lima Lima

4

5

5

Centro Medico

Clinica San

Judas Tadeo

Dextre

Espinoza

Augusto

Peru Lima Lima

4

5

6

Hospital

Nacional

Arzobispo Loayza

Medina-Santan

der Boris

Peru Lima Lima

4

5

7

Clinica Virgen

Maria

Auxiliadora

Vargas-Gonzal

es Rolando

Peru Piura Piura

4

5

8

NZOZ

Specjalistyczny

Osrodek

Arciszewska

Malgorzata

Poland Bialystok Bialystok

4

5

9

NZOZ Diab Serwis

S.C.

Popenda

Grazyna

Poland Chorzow Chorzow

4

6

0

NZOZ SALVIA Madej Andrzej Poland Katowice Katowice

4

6

1

Krakowskie

Centrum Medyczne

Sp. z o.o.

Kowalczyk-Mic

halek Martyna

Poland Krakow Krakow

4

6

2

NZOZ Centrum

Medyczne

ProMiMed Sp. z

o.o., sp.k

Necki Miroslaw Poland Krakow Krakow

4

6

3

SPZOZ

Uniwersytecki

Szpital

Kliniczny nr 1

Nowicki Michal Poland Lodz Lodz

4

6

4

NZOZ Przychodnia

Specjalistyczna

MEDICA

Skokowska Ewa Poland Lublin Lublin

4

6

5

Centrum Medyczne

Medyk

Mazur

Stanislaw

Poland Rzeszow Rzeszow

4

6

6

Samodzielny

Publiczny

Szpital

Kliniczny Nr 2

PUM w Szczecini

Ciechanowski

Kazimierz

Poland Szczecin Szczecin

4 Centrum Uslug Wruk Michal Poland Szczecinek Szczecinek

6

7

Medycznych

Dializa

4

6

8

Medica pro

Familia Sp. z

o.o. S.K.A

Klodawska

Katarzyna

Poland Warsaw Warsaw

4

6

9

Hospital Curry

Cabral,PT

Ferreira

Annibal

Portuga

l

Lisbon Lisbon

4

7

0

Associacao

Protectora dos

Diabeticos de

Portugal

Brine Rita Portuga

l

Lisbon Lisbon

4

7

1

Centro

Hospitalar do

Porto

Cabrita

Antonio

Portuga

l

Porto Porto

4

7

2

Health

Preventive

Services

Comulada-Rive

ra Angel

Puerto

Rico

Bayamon Bayamon

4

7

3

Instituto Renal

del Este

Galindo Ramos

Eugenia

Puerto

Rico

Caguas Caguas

4

7

4

Caparra Internal

Medicine

Matta Fontanet

Evelyn

Puerto

Rico

Rio Grande Rio Grande

4

7

5

University of

Puerto Rico

Burgos-Calder

on Rafael

Puerto

Rico

Rio Piedras Rio Piedras

4

7

6

PR Renal Health

and Research

INC.

Calderon-Orti

z, Ricardo

Puerto

Rico

Toa Baja Toa Baja

4

7

7

O.D. Medica SRL Tivadar Simona Romania Bucharest Bucharest

4

7

8

Centrul Medical

Unirea SRL

Hancu Nicolae Romania Cluj-Napoc

a

Cluj-Napoc

a

4

7

9

Spitalul Clinic

Judetean de

Urgenta

Cluj-Napoca

Duma Livia Romania Cluj-Napoc

a

Cluj-Napoc

a

4

8

0

Spitalul Clinic

Judetean de

Urgenta

Constanta

Tuta Liliana Romania Constanta Constanta

4

8

1

Milena Sante SRL Mistodie

Cristina

Romania Galati Galati

4

8

2

Consultmed SRL Pintilei Ella Romania Iasi Iasi

4

8

3

Municipal

Clinical

Hospital

Bako Gabriel Romania Oradea Oradea

4

8

4

Spitalul

Judetean de

Urgenta Pitesti

Tutescu

Adriana

Romania Pitesti Pitesti

4

8

5

SC Centrul

Medical

Munteanu

Mircea

Romania Timisoara Timisoara

4

8

6

Sptalul Clinic

Judetean de

Urgenta

Timisoara

Petrica Ligia Romania Timisoara Timisoara

4

8

7

Sptalul Clinic

Judetean de

Urgenta

Timisoara

Timar Romulus Romania Timisoara Timisoara

4

8

8

City Hospital No

6

Kuzin Anatoly Russian

Federat

ion

Chelyabins

k

Chelyabins

k

4

8

9

Gatchina Central

District

Clinical

Hospital

Yavdosyuk

Andrey

Russian

Federat

ion

Gatchina Gatchina

4

9

0

Irkutsk State

Medical Academy

of Postgraduate

Education

Bardymova

Tatiana

Russian

Federat

ion

Irkutsk Irkutsk

4

9

1

Kazan State

Medical

University

Sigitova Olga Russian

Federat

ion

Republic of

Tatarstan

Kazan

4

9

2

Kazan State

Medical

University

Maksudova

Adelya

Russian

Federat

ion

Republic of

Tatarstan

Kazan

4

9

3

Kirov City

Clinical

Hospital 1

Solovev Oleg Russian

Federat

ion

Kirov Kirov

4 Krasnoyarsk Rechkova Elena Russian Krasnoyars Krasnoyars

9

4

Interdistrict

Clinical

Emergency Care

Hospital

Federat

ion

k k

4

9

5

Endocrinology

Research Center

Shamkhalova

Minara

Russian

Federat

ion

Moscow Moscow

4

9

6

Moscow -

Out-patient

Clinic #3

Pikalova

Natalia

Russian

Federat

ion

Moscow Moscow

4

9

7

City Hosp 33 of

Leninskiy

District of City

Nizhniy Novgorod

Pichkov Dmitry Russian

Federat

ion

Nizhniy

Novgorod

Nizhniy

Novgorod

4

9

8

Scientific

Instituti of

Clinical and

Experimental

Lymphology

Klimontov

Vadim

Russian

Federat

ion

Novosibirs

k

Novosibirs

k

4

9

9

Orenburg State

Medical Academy

Sayfutdinov

Rustam

Russian

Federat

ion

Orenburg Orenburg

5

0

0

Perm Regional

Hospital for War

Veterans

Koziolova

Natalya

Russian

Federat

ion

Perm Perm

5

0

1

Republican

Hospital named

after V. A.

Baranov

Barysheva Olga Russian

Federat

ion

Petrozavod

sk

Petrozavod

sk

5

0

2

City Out-patient

Clinic #17

Lantseva Olga Russian

Federat

ion

Saint-Pete

rsburg

Saint-Pete

rsburg

5

0

3

City Clinical

Hospital # 38

named after N.A.

Semashko

Zrazhevskiy

Konstantin

Russian

Federat

ion

Saint-Pete

rsburg

Saint-Pete

rsburg

5

0

4

St. Petersburg

Medical Univ na

I.P. Pavlov

Karonova

Tatiana

Russian

Federat

ion

Saint-Pete

rsburg

Saint-Pete

rsburg

5

0

5

City Clinical

Hospital # 31

Essaian Ashot Russian

Federat

ion

Saint-Pete

rsburg

Saint-Pete

rsburg

5

0

GBOU VPO Saratov

State Medical

Shvarts Yuri Russian

Federat

Saratov Saratov

6 University ion

5

0

7

Smolensk State

Medical Academy

Reshedko

Galina

Russian

Federat

ion

Smolensk Smolensk

5

0

8

Federal State

Institution

Sardinov

Ruslan

Russian

Federat

ion

Republic of

Tatarstan

St.

Petersburg

5

0

9

Siberian State

Medical

University

Samoylova

Yulia

Russian

Federat

ion

Tomsk Tomsk

5

1

0

Research

Institute for

Cardiology

Mordovin

Viktor

Russian

Federat

ion

Tomsk Tomsk

5

1

1

Regional

Clinical

Hospital of

Yaroslavl Region

Marasaev

Vyacheslav

Russian

Federat

ion

Republic of

Tatarstan

Yaroslavl

5

1

2

Tan Tock Seng

Hospital

Liew Adrian Singapo

re

Singapore Singapore

5

1

3

Khoo Teck Puat

Hospital

Yeoh Lee Ying Singapo

re

Singapore Singapore

5

1

4

National

University

Hospital

Teo, Boon Wee Singapo

re

Singapore Singapore

5

1

5

Metabolic Center

of Dr K.Raslova,

ltd

Raslova

Katarina

Slovaki

a

Bratislava Bratislava

5

1

6

Medispektrum,

sro

Ilavska

Adriana

Slovaki

a

Bratislava Bratislava

5

1

7

FMC Dialysis

Services

Fekete Jozef Slovaki

a

Bratislava Bratislava

5

1

8

Slovenska

Zdravotnica

Univerzita

Oksa Adrian Slovaki

a

Bratislava Bratislava

5

1

9

ProVitae-Medica

l Centre

Zachar Andrej Slovaki

a

Bratislava Bratislava

5

2

0

FMC-dialyzacne

sluzby, spol.s

r.o

Obetkova Ida Slovaki

a

Hlohovec Hlohovec

5

2

1

Medikol s.r.o. Kolesarova Eva Slovaki

a

Kosice Kosice

5

2

2

AGTO spol.

s.r.o.

Tkac Ivan Slovaki

a

Kosice Kosice

5

2

3

FMC Dialyzacne

sluzby s.r.o.

Rosenberger

Jaroslav

Slovaki

a

Kosice Kosice

5

2

4

SMOLKO s.r.o. Smolko Peter Slovaki

a

Kosice Kosice

5

2

5

Interna SK

s.r.o.

Fulopova Alla Slovaki

a

Svidnik Svidnik

5

2

6

Groote Schuur

Hospital

Okpechi Ikechi South

Africa

Western

Cape

Cape Town

5

2

7

Langeberg

Clinical Trials

Trokis Julien South

Africa

Western

Cape

Cape Town

5

2

8

Dr P J Sebastian Sebastian

Peter

South

Africa

KwaZulu-Na

tal

Durban

5

2

9

Newkwa Medical

Centre

Ramlachan

Padaruth

South

Africa

KwaZulu-Na

tal

Durban

5

3

0

St. Augustine's

Hospital

Naiker

Puvanesveri

South

Africa

KwaZulu-Na

tal

Durban

5

3

1

Centre for

Diabetes and

Endocrinology

Distiller

Lawrence

South

Africa

Gauteng Johannesbu

rg

5

3

2

Makan, Lenasia,

SA

Makan Hemant South

Africa

Lenasia Lenasia

5

3

3

Paarl Research

Centre

Coetzee

Kathleen

South

Africa

Western

Cape

Paarl

5

3

4

Soweto Clinical

Trial Centre

Bhorat Asad South

Africa

Soweto Soweto

5

3

Clinical

Projects

van Zyl Louis South

Africa

Western

Cape

Worcester

5 Research

5

3

6

Complejo

Hospitalario

Universitario de

A Coruna

Soto Gonzalez

Alfonso

Spain A Coruna A Coruna

5

3

7

Hospital

Universitario

Germans Trias i

Pujol

Bonet Jose Spain Badalona -

Barcelona

Badalona -

Barcelona

5

3

8

Hospital Parc de

Salut del Mar

Pascual Santos

Julio

Spain Barcelona Barcelona

5

3

9

Hospital

Universitario

Bellvitge

Grinyo Josep Spain Barcelona Barcelona

5

4

0

Hospital

Universitario

Vall d'Hebron

Seron Daniel Spain Barcelona Barcelona

5

4

1

Fundacion

Puigvert

Calero

Gonzalez

Francesca

Spain Barcelona Barcelona

5

4

2

Hospital

Universitario de

Basurto

Arrieta

Lezarna Javier

Spain Bilbao Bilbao

5

4

3

Hospital da

Costa

Cigarran

Guldris

Secundino

Spain Burela Burela

5

4

4

Hospital

Universitario

Reina Sofia

Santamaria

Olmo Rafael

Spain Cordoba Cordoba

5

4

5

Hospital

Universitario de

Gran Canarias

Dr. Negrin

Rodriguez-Per

ez Jose

Spain Las Palmas Las Palmas

5

4

6

Hospital

Universitario

Arnau de

Vilanova

Fernandez

Giraldez

Elvira

Spain Lleida Lleida

5

4

7

Hospital

Universitario

Fundacion

Alcorcon

Fernandez

Juarez Gema

Spain Madrid Madrid

5

4

Fundacion

Jimenez Diaz

Egido Jesus Spain Madrid Madrid

8

5

4

9

Hospital Clinico

San Carlos

Herrero Calvo

Jose

Spain Madrid Madrid

5

5

0

Hospital

Universitario 12

de Octubre

Praga Terente

Manuel

Spain Madrid Madrid

5

5

1

Hospital

Universitarrio

Puerta de Hierro

Majadahonda

Marques Vidas

Maria

Spain Madrid Madrid

5

5

2

Hospital

Universitario

Virgen de la

Victoria

Valera Cortes

Ildefonso

Spain Malaga Malaga

5

5

3

Hospital

Universitario

Marques de

Valdecilla

Fernandez

Fresnedo Gema

Spain Santander

(Cantabria

)

Santander

(Cantabria

)

5

5

4

Hospital

Universitario

Nuestra Senora

de Candelaria

Navarro

Gonzalez Juan

Spain Tenerife Tenerife

5

5

5

Hospital General

Univ de Valencia

Galan Antonio Spain Valencia Valencia

5

5

6

Hospital

Universitario

Dr. Peset

Gorriz Jose Spain Valencia Valencia

5

5

7

Hospital

Universitari i

Politecnin la Fe

Hernandez-Jar

as Julio

Spain Valencia Valencia

5

5

8

Hospital de

Txagorritxu

Minguela

Pesquera Jose

Ignacio

Spain Vitoria Vitoria

5

5

9

Orebro

Universitetssju

khus

Hellberg Olof Sweden Orebro Orebro

5

6

0

Uppsala

University

Hospital

Fellstrom

Bengt

Sweden Uppsala Uppsala

5

6

1

Hualien Tzu Chi

Hospital

Wu Du-An China Taiwan Hualien

5

6

2

Far Eastern

Memorial

Hospital

Jiang Ju-Ying China Taiwan New Taipei

5

6

3

Cardinal Tien

Hospital

Dee Pei China Taiwan New Taipei

5

6

4

China Medical

University

Hospital

Chen Ching-Chu China Taiwan Taichung

5

6

5

Taichung

Veterans General

Hospital

Sheu Wayne China Taiwan Taichung

5

6

6

Chung Shan

Medical

University

Huang

Chien-Ning

China Taiwan Taichung

5

6

7

Kuang Tien

General Hospital

Tseng

Shih-Ting

China Taiwan Taichung

5

6

8

Taichung

Hospital

Sheen Yi-Jing China Taiwan Taichung

5

6

9

Chi-Mei Medical

Center

Tien Kai-Jen China Taiwan Tainan

5

7

0

Cathay General

Hospital

Lin Ching-Ling China Taiwan Taipei

5

7

1

Taipei Medical

University

Hospital

Wu Mai-Szu China Taiwan Taipei

5

7

2

MacKay Memorial

Hospital

Chien Ming-Nan China Taiwan Taipei

5

7

3

Baskent

University

School of

Medicine

Sezer Siren Turkey Ankara Ankara

5

7

4

Akdeniz

University

School of

Medicine

Sari Ramazan Turkey Ankara Ankara

5

7

5

Adnan Menderes

University

Yenicerioglu

Yavuz

Turkey Aydin Aydin

5

7

6

Istanbul

University

Medical Faculty

Satman Ilhan Turkey Istanbul Istanbul

5

7

7

Istanbul

University

Medical Faculty

Yildiz

Alaattin

Turkey Istanbul Istanbul

5

7

8

Kocaeli

University

Medical Faculty

Kalender

Gonullu Betul

Turkey Kocaeli Kocaeli

5

7

9

Chernivtsi

Regional

Clinical

Hospital

Zub Lilia Ukraine Chernivtsi Chernivtsi

5

8

0

Ukrainian State

Institution of

Medical and

Social Problems

Panina

Svitlana

Ukraine Dnipropetr

ovsk

Dnipropetr

ovsk

5

8

1

Ivano-Frankivsk

Regional

Clinical

Hospital

Legun Oleg Ukraine Ivano-Fran

kivsk

Ivano-Fran

kivsk

5

8

2

Kharkiv City

Clinical

Emergency

Hospital

Bilchenko

Oleksandr

Ukraine Kharkiv Kharkiv

5

8

3

Kharkov City

Clinical

Hospital #27

Zolotaikina

Viktoriia

Ukraine Kharkiv Kharkiv

5

8

4

SI Institute of

Therapy AMS of

Ukraine n.a.

Mala L.T.

Topchii Ivan Ukraine Kharkiv Kharkiv

5

8

5

VP Komissarenko

National Academy

of Medical

Sciences

Korpachev

Vadym

Ukraine Kiev Kiev

5

8

6

Kiev Regional

Clinical

Hospital

Shen Andriy Ukraine Kyiv Kyiv

5

8

7

Polyclinic of

Administration

of Medical

Services

Mankovskyy

Borys

Ukraine Kyiv Kyiv

5 Communal Petrosyan Ukraine Odesa Odesa

8

8

Institution

Odesa Regional

Clinical

Hospital

Olena

5

8

9

Transcarpathian

Regional Clin.

Hos. Named after

Andriy Novak

Stryzhak Vasyl Ukraine Uzhgorod Uzhgorod

5

9

0

Clinic of

Scientific

Research

Institute for

Hadicapped

Shevchuk

Sergii

Ukraine Vinnytsya Vinnytsya

5

9

1

Vinnytsya

National Medical

University n.a.

M.I. Pyrogov

Stanislavchuk

Mykola

Ukraine Vinnytsya Vinnytsya

5

9

2

Regional

Clinical

Hospital of

Zhytomyr

Kuskalo Petro Ukraine Zhytomyr Zhytomyr

5

9

3

Belfast City

Hospital

Maxwell Peter United

Kingdom

Belfast Belfast

5

9

4

Ninewells

Hospital

Brennan

Geraldine

United

Kingdom

Dundee Dundee

5

9

5

South Glasgow

Universita Hospi

Mark Patrick United

Kingdom

Glasgow Glasgow

5

9

6

Kings College

Hospital

Kon, Sui Phin United

Kingdom

London London

5

9

7

Guy's Hospital Gnudi Luigi United

Kingdom

London London

5

9

8

The Royal Free

Hospital

Patel Dipesh United

Kingdom

London London

5

9

9

North Middlesex

Hospital NHS

Trust

Tindall Hilary United

Kingdom

London London

6

0

Salford Royal

NHS Foundation

Kalra Phillip United

Kingdom

Salford Salford

0 Trust

6

0

1

Queen Mary

Hospital

Sydney Tang 中国 Hong Kong Hong Kong

6

0

2

Prince of Wales

Hospital

Risa Ozaki 中国 Hong Kong Hong Kong

6

0

3

Queen Mary

Hospital

Kathryn Tan 中国 Hong Kong Hong Kong

6

0

4

河北医科大学第

二医院

傅淑霞 中国 河北省 石家庄

6

0

5

宁波市第二医院 罗群 中国 浙江省 宁波

6

0

6

郑州大学第一附

属医院

刘章锁 中国 河南省 郑州

七、伦理委员会信息

序号 名称 审查结论 审查日期

1 南方医科大学南方医院医学伦理

委员会

同意 2014-10-23

八、试验状态

主动暂停 艾伯维因收集的终点事件远低于预期，决定提前终止研究